Abstract: A chewing gum for mucosal delivery of cannabinoids, the chewing gum being formulated as an extruded chewing gum including water-soluble chewing gum ingredients mixed into water-insoluble gum base, wherein the gum base includes one or more natural resins in an amount of 10-40% by weight of the gum base, one or more elastomers in an amount of 3-30% by weight of the gum base, and one or more elastomer plasticizers in an amount of 8-50% by weight of the gum base, and wherein the chewing gum includes one or more cannabinoids, and wherein the release rate of the one or more cannabinoids is at least 10% by weight of the one or more cannabinoids within the first 5 minutes upon oral administration.

Abstract: Chewable sustained release compositions and their methods of production are provided. The sustained release compositions contain amphipathic lipids and matrix-forming polymers, which are used to encapsulate various drugs and active ingredients. The chewable sustained release compositions can maintain their sustained release properties even after being fragmented into a plurality of pieces.

Abstract: The invention relates to a chewing gum composition for use in the alleviation of xerostomia induced by radiotherapy treatment, where the chewing gum composition comprises gum base and substantially no flavour ingredients. Moreover, the invention also relates to a dosage regimen for administering the chewing gum composition for use in alleviation of xerostomia induced by radiotherapy treatment. So in one embodiment of the invention the chewing gum composition is administered to a human subject before and/or during and/or after radiotherapy treatment.

Abstract: The invention relates to a chewable tablet including a polymer system, tobacco powder, flavor and sweetener, at least about 70% by weight of the polymer system being polyvinyl acetate (PVAc) and less than 10% by weight of the polymer system being polymer having a molecular weight (Mw) of greater than about 50000 g/mol.

Abstract: An amphiphilic polymeric material which has a straight or branched chain polymer backbone and a multiplicity of side chains attached to the backbone, wherein the backbone is a copolymer of at least one ethylenically-unsaturated aliphatic hydrocarbon monomer and maleic anhydride, or is a terpolymer of maleic anhydride, ethylene, and a further ethylenically unsaturated monomer. A method of synthesizing said polymeric material is also provided, together with chewing gum bases, compositions and emulsions comprising amphiphilic polymeric materials.

Abstract: The present invention relates to rolling compound powders comprising hydrogenated or non-hydrogenated isomaltulose for applying to the surface of chewing gum core materials, chewing gum products comprising such rolling compound powders, processes for reducing the stickiness of compositions of chewing gum core materials by using hydrogenated or non-hydrogenated isomaltulose-containing rolling compound powders in chewing gum preparation processes as well as the use of hydrogenated or non-hydrogenated isomaltulose in rolling compound powders for applying to the surface of chewing gum core materials.

Abstract: A photo-degradable chewing gum base composition including an elastomer; and a block copolymer of vinyl acetate and methylphenylsilane having a structure of formula (I)— wherein m and p are integers in the range of 1 to 500, and n is an integer in the range of 2 to 100, is disclosed. The block copolymer facilitates environmental degradation of improperly disposed chewing gum cuds. Also described is a method of preparing a photo-degradable chewing gum composition.

Abstract: The present invention relates to various polymer compounds and/or formulations and to methods for the synthesis of same. In one embodiment, the present invention is related to polymer compounds and/or formulations that enable one to more easily remove sticky articles (e.g., chewing gum) from various surfaces.

Abstract: Methods and systems for providing easy access to information and sharing are provided. Embodiments of the present invention enable a host to grant access to published content to one or more users in a manner in which the user(s) can scan small portions of information to decide which information is desired. The embodiments described herein enable, for example, a user to see a library of content that is larger than the storage capacity of the computing unit used by the user. The sharing of information is also secured through the use of auto-lock keys and the creation of abstract identities for the host and each user.

Abstract: Architecture that provides model-based systems management in virtualized and non-virtualized environments. A security component provides security models which define security requirements for services. A management component applies one or more of the security models during the lifecycle of virtual machines and services. The lifecycle can include initial deployment, expansion, moving servers, monitoring, and reporting. The architecture creates a formal description model of how a virtual machine or a service (composition of multiple virtual machines) is secured. The security requirements information can also be fed back to the general management system which uses this information in its own activities such as to guide the placement of workloads on servers can be security related.

Abstract: A non-stick chewing gum is disclosed. More specifically, a gum base is mixed with at least one pulverized natural food product that increases removability of the gum cud without sacrificing chewing sensation. In one embodiment, the particle size of the pulverized natural products containing fiber and other components (e.g. beans, fruit, nuts, vegetables, spices, ginseng, etc.) can range from 10 to 2000 microns in dimension before the chewing gum is chewed. The particles of the natural products can generate steric hindrance between the gum base and a contacted surface to reduce interfacial contact area therebetween and further enhance detackification effect of the chewing gum.

Abstract: A chewing gum comprising at least one active pharmaceutical ingredient (API) with a core onto which is applied at least one inner polymer film coating and thereafter onto which is applied at least one outer hard coating. A preferred API is nicotine. Flavoring agents may be incorporated in the core, in the at least one inner polymer film coating and/or in the at least one outer hard coating. The gums formed exhibit a long lasting effect of flavoring agent(s) and result in the domination of flavoring agents in the coating(s) over flavoring agent(s) in the core, thereby (a) avoiding problems of chemical or pharmaceutical incompatibility between an API in the core and flavoring agent(s) in the coating(s) and (b) achieving an increased control of the release of the API and of non-active excipients.

Abstract: A chewing gum comprises a primary chewing gum composition comprising gum base, a sweetener and a flavoring agent and a food acceptable delayed-release modification agent. The delayed-release modification agent reacts with the primary chewing gum composition after a chewed cud of the gum composition is formed, causing the primary gum to exhibit increased environmental acceptability after the chewed cud is discarded.

Abstract: The invention relates to a gum base which, in comparison with known gum bases, has an improved aroma, taste and improved oxidation stability, has only low stickiness, and in addition is simple to process. It is a homogeneous composition containing 15-45% by weight of polyvinyl acetate, 10-30% by weight of vinyl laurate-vinyl acetate copolymers, 15-45% by weight of fillers, 5-30% by weight of waxes or fats, 1-10% by weight of plasticizers and 1-10% by weight of emulsifiers.

Abstract: The present invention relates to a chewing gum base formulation comprising a biocompatible particulate polymer having an average particle size of from about 200 ?m to about 2000 ?m wherein the polymer fibrillates when subjected to a shear stress such as that encountered during chewing.

Abstract: An additive for gum comprising formulations of alkyl dimethicone crosspolymer, which is added to the gum formulations, compositions and products to reduce adhesion of the chewed gum to surfaces and to improve the aesthetic and manufacturing process characteristics of the gum. Gum having the additive is likewise disclosed as are methods of preparing the additives, as well as methods of using the gum having the additives.

Abstract: The invention relates to a non-tack gum base, a chewing gum preparation produced therefrom and also methods for production thereof. It is a homogeneous composition comprising polyvinyl acetate in an amount of 25-90% by weight, vinyl laurate-vinyl acetate copolymer in an amount of 5-70% by weight, and a softener in an amount of 1%-15% by weight, in each case based on the total weight of the composition.

Abstract: A chewing gum base which is cud-forming and chewable at mouth temperature contains a food acceptable tri-block copolymer having the form A-B-A or A-B-C and comprising a soft mid-block which constitutes at least 30 wt. % of the total polymer and hard end-blocks each having a glass transition temperature below 70° C. The tri-block copolymer is optionally plasticized with a compatible di-block copolymer to function as an elastomer system in the gum base.

Abstract: A gum base, which when formulated into a chewing gum provides a gum cud removable from concrete and cement surfaces, contains 3 to 30 wt. % elastomer, 0 to 32 wt. % elastomer solvent and 0 to 8% paraffin wax and has a polarity index of less than 2.00 MPa½ and chewing gums containing the gum base.

Abstract: A gum base which, when formulated into a chewing gum, provides a gum cud removable from environmental surfaces, contains 40-95 wt. % polyethylene having a weight average molecular weight of 2000 to 23000 daltons.

Abstract: The invention relates to a method for producing chewing gum granules. The method comprises at least the steps of feeding a gum composition including at least gum base into an extruder (2), pressurizing the gum composition in the extruder, extruding the gum composition through a die plate (5), and cutting the extruded gum composition in a liquid filled chamber (4). Flavor is added to the composition in the extruder prior to the granulation into cooling liquid. The temperature and pressure of the flavored gum composition is controlled so that the temperature is below 70° C. when the pressure is in the range from 1 to 5 hPa.

Abstract: A chewing gum comprising at least one active pharmaceutical ingredient (API) with a core onto which is applied at least one inner polymer film coating and thereafter onto which is applied at least one outer hard coating. A preferred API is nicotine. Flavoring agents may be incorporated in the core, in the at least one inner polymer film coating and/or in the at least one outer hard coating. The gums formed exhibit a long lasting effect of flavoring agent(s) and result in the domination of flavoring agents in the coating(s) over flavoring agent(s) in the core, thereby (a) avoiding problems of chemical or pharmaceutical incompatibility between an API in the core and flavoring agent(s) in the coating(s) and (b) achieving an increased control of the release of the API and of non-active excipients.

Abstract: The present invention provides gum base compositions and chewing gum compositions having non stick or reduced-stick properties and/or increased degradability. Methods of preparing the gum base and chewing gum compositions, as well as methods of use, are provided.

Abstract: A polymeric material having low tack which has a straight or branched chain carbon-carbon polymer backbone and a multiplicity of side chains attached to the backbone wherein the side chains, which are attached directly to carbon atoms of the polymer backbone, have the formula wherein R1 is H, —C(O)OR4 or —C(O)Q and R2 is —C(O)OR4 or —C(O)Q provided that at least one of R1 and R2 is the group —C(O)Q; R3 is H or —CH3; R4 is H or an alkyl group having from 1 to 6 carbon atoms; Q is a group having the formula —O—(YO)b—(ZO)c—R5? wherein each of Y and Z is, independently, an alkylene group having from 2 to 4 carbon atoms and R5 is H or an alkyl group having from 1 to 4 carbon atoms; a is 3 or 4 and each of b and c is, independently, 0 or an integer of from 1 to 125 provided that the sum b+c has a value in the range of from 10 to 250, preferably from 10 to 120.

Abstract: Disclosed are polymers derived from vinyl acetate, vinyl alcohol and other monomers with elastic and plastic characteristics, which are useful to prepare gum base for chewing gum with a low environmental impact and reduced adherence.

Abstract: A compressed chewing gum tablet and gum base granule for such tablet including at least one elastomer in an amount of about 0% to about 35% by weight of the gum base, at least two resins in an amount of about 15% to about 60% by weight of the gum base, gum base ingredients and where the at least two resins include natural resin in an amount of about of about 5% to about 40% by weight of the gum base, and synthetic resin in an amount of about 10% to about 40% by weight of the gum base.

Abstract: Novel methods of determining efficacy of a treatment of inflammatory diseases of the bowel in mammals are provided. The methods are of use in screening and determining the efficacy of treatments of inflammatory diseases of the bowel, and for determining the efficacy response of individual sufferers of inflammatory diseases of the bowel to a given regime. Kits for carrying out the method are also provided.

Abstract: The present invention relates to compositions and edible orally delivered products, such as confectioneries and chewing gum, which include taste potentiators to enhance the perception of active substances contained therein. More specifically, some embodiments provide potentiator compositions, which include at least one active substance and at least one taste potentiator. The active substance and/or taste potentiator may be encapsulated in some embodiments to modify the release rate of the composition upon consumption.

Abstract: The present invention relates to a gum base formulation suitable for the production of a chewing gum with good sensory properties and good flavor release in combination with anti-adhesive properties in respect of teeth, dentures and the like typical of formulations containing polyvinyl acetate. This gum base formulation does not stick to teeth and it is characterized by having the following composition by weight: (a) elastomers ?8-16% (b) emulsifiers and/or technological auxiliaries 18-30% (c) adjuvants 15-40% (d) vegetable resins and/or vegetable resin esters 26-45% (e) antioxidants 0-2% and by not containing polyvinyl acetate.

Abstract: The present invention relates to compositions and edible orally delivered products, such as confectioneries and chewing gum, which include taste potentiators to enhance the perception of active substances contained therein. More specifically, some embodiments provide potentiator compositions, which include at least one active substance and at least one taste potentiator. The active substance and/or taste potentiator may be encapsulated in some embodiments to modify the release rate of the composition upon consumption.

Abstract: The invention relates to chewing gum comprising at least two different biodegradable polymers. According to the invention, a chewing gum comprising at least two different biodegradable polymers exhibits an improved texture prior to any adding of for example softeners. It has been realized that the desired chewing gum texture properties, contrary to every expectation and any prior art disclosures, may actually be obtained when combining biodegradable chewing gum polymers, for example in the gum base or in the final gum.

Abstract: The invention provide a gum base composition which has an excellent chewing texture and is disintegratable and biodegradable comprising biodegradable ingredients, including a lactic acid polymer comprising a poly-L-lactic acid polymer and/or other lactic acid polymers having a glass transition temperature higher than 50° C. in an amount of from 5% by weight to 60% by weight, and an emulsifying plasticizer in an amount of from 1% by weight to 20% by weight. The weight average molecular weight of the lactic acid polymer to be used is preferably 50,000 to 200,000.

Abstract: The present invention concerns an amphiphilic polymeric material which comprises a straight or branched chain carbon-carbon backbone and a multiplicity of side chains attached to the backbone, wherein the side chains have formula (I). At least one of R1 and R2 is the group —C(O)Q; wherein Q comprises a hydrophilic polymeric group terminated with an amine. Chewing gum bases and chewing gum compositions comprising the amphiphilic polymeric material are provided.

Abstract: The present invention provides a method for continuously producing pieces of liquid-filled gum material, including applying an anti-sticking agent to the rope of liquid-filled gum material before it is individually cut into pieces. The invention further provides for a liquid-filled chewing gum including a liquid-fill composition, and a gum region surrounding the liquid-fill composition, where the gum region includes an anti-sticking agent that reduces the tendency of the gum region to stick to the molds and operating machinery during gum manufacturing.

Abstract: A chewing gum composition includes at least one biodegradable gum base polymer, at least one sweetener and at least one flavor, the composition having low tack effected by a plurality of side chains attached to the backbone of at least one gum base polymer.

Abstract: A packaged confectionary product includes a biodegradable chewing gum composition and a package assembly forming a humidity barrier to the biodegradable chewing gum composition. According to an embodiment of the invention significant reduction of pre-degradation of gum polymers may be obtained if the confectionary product is encapsulated within a package assembly which includes a humidity barrier to the chewing gum composition contained in the package.

Abstract: An edible pet chew that is made of rehydrated hide about an inner fill via a positioning shealth.

Abstract: The invention relates to a chewing gum piece comprising at least one inner filling (2) being enclosed by sugarless chewing gum substance (1), said chewing gum piece being provided with an anti-sticking agent (4), and said chewing gum piece being provided with a coating (6) at least partly encapsulating said chewing gum piece and said anti-sticking agent.

Abstract: The present invention provides gum base compositions and chewing gum compositions having non stick or reduced-stick properties and/or increased degradability. The compositions include a terpolymer of methylvinyl ether, maleic anhydride and maleic acid, which provide increased degradability. Methods of preparing the gum base and chewing gum compositions, as well as methods of use, are provided.

Abstract: The invention relates to a chewing gum comprising at least one biodegradable polymer in an amount of from about 0.1% to about 95%, said biodegradable polymer having a glass transition temperature (Tg) above 37° C. and having a molecular weight (Mn) within the range of approximately 500 to 60000 g/mol and wherein said chewing gum comprises less than approximately 5% by weight of natural resins.

Abstract: The present invention provides gum base compositions and chewing gum compositions having non stick or reduced-stick properties and/or increased degradability. Methods of preparing the gum base and chewing gum compositions, as well as methods of use, are provided.

Abstract: The invention relates to a chewing gum comprising chewing gum ingredients, said chewing gum comprising at least one elastomer and at least one resin, said at least one resin comprising at least one synthetic biodegradable homopolymer resin, the amount of said synthetic biodegradable homopolymer of said chewing gum being from about ½% to 60% by weight of said chewing gum. The obtained non-tack properties combined with acceptable chew feel is according to an embodiment of the invention obtained by a combination of a biodegradable homopolymer and an elastomer in the chewing gum.

Abstract: A chewing gum base essentially free of non-silica fillers, comprising high molecular weight polyisobutylene, optionally amorphous silica and polyvinylacetate and powdered lecithin present in the chewing gum composition and optionally spray-dried flavor in the chewing gum composition.

Abstract: Disclosed is a chewing gum composition capable of eliminating nicotine component from the body of a person chewing the chewing gum. Such a chewing gum composition functions to convert the nicotine produced in a human body after smoking to cotinine and to discharge the cotinine into urine. Accordingly, by chewing the chewing gum of the present invention, not only nicotine can be eliminated from the body, but also the incidence of cancer due to nicotine can be largely reduced.

Abstract: A method is provided for the total manufacture of chewing gum on a continuous basis. The method uses a continuous high efficiency mixer which includes at least one conveyor element that is not located under a feed port.

Abstract: Disclosed are stable portable oral care confectionery compositions which provide enhanced oral malodour benefits. Compositions of the present invention can optionally have one or more additional oral care benefits. The confectionery compositions comprise: (i) greater than about 10 ppm of a first metal cation selected from the metals of groups 5, 6, 7, 8, 9, 10, 11, 12, 14, 16 of the periodic table; (ii) greater than about 10 ppm of a second metal cation different from the first metal cation and selected from the metals of groups 5, 6, 7, 8, 9, 10, 11, 12, 14, 16 of the periodic table; (iii) less than about 10% water; and (iv) a confectionery carrier wherein the ratio of the first metal cation to the second metal cation is in the range of from about 50:1 to about 1:50.

Abstract: Disclosed are stable portable oral care confectionery compositions which provide enhanced oral malodour benefits combined with enhanced anti-calculus benefits, wherein the confectionery compositions comprise: (i) a polyphosphate material with an average anion chain length of greater than or equal to 3; (ii) greater than about 10 ppm of a metal cation selected from the metals of groups 5, 6, 7, 8, 9, 10, 11, 12, 14, 16 of the periodic table; (iii) less than about 10% water; and (iv) a suitable confectionery carrier material wherein the ratio of polyphosphate anion to metal cation is in the range of from about 10:1 to about 1:1.

Abstract: Disclosed are stable, portable, oral care confectionery wherein the confectionery composition has a crunchy texture which acts to reinforce for the consumer the oral care benefit of the product. A crunchy, non-cariogenic oral care confectionery composition comprises: (i) from about 0.1% to about 50%, by weight of the composition, of an oral care active selected from the group consisting of anti-calculus agents; anti-plaque agents; desensitising agents; oral malodour control agents; H2 antagonists; and mixtures thereof; (ii) from about 0.1% to about 50%, by weight of the composition, of a solid particulate wherein the solid particulate has a particle size such that is passes through a 2000 &mgr;m mesh and is retained by a 100 &mgr;m mesh and has an aqueous solubility of at least 1 g per 100 ml at 25° C.

Abstract: An oral care composition comprising: (i) an effective amount of a antibacterial seed or pulp extract from the Citrus plant family; the Vitis plant family; and mixtures thereof; (ii) an oral care active selected from the group consisting of anti-calculus agents; anti-plaque agents; fluoride ion source; desensitizing agents; oral malodor control agents; H2 antagonists; and mixtures thereof; and (iii) a pharmaceutically acceptable carrier.

Abstract: Disclosed are stable oral care compositions, preferably confectionery compositions, which provide enhanced oral malodour benefits combined with one or more additional oral care benefits, wherein the compositions comprise: (i) a polyphosphate material with an average anion chain length of 3 or greater; (ii) greater than about 10 ppm of a first metal cation selected from the metals of groups 5, 6, 7, 8, 9, 10, 11, 12, 14, 16 of the periodic table; (iii) greater than about 10 ppm of a second metal cation selected from the metals of groups 5, 6, 7, 8, 9, 10, 11, 12, 14, 16 of the periodic table; and (iv) a pharmaceutically acceptable carrier, wherein the molar ratio of polyphosphate anion to the total level of first and second metal cation combined is in the range of from about 10:1 to about 1:1 and wherein the molar ratio of the first metal cation to the second metal cation is in the range of from about 50:1 to about 1:50.