Heterocyclic Patents (Class 426/536)
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Patent number: 5932267Abstract: Compounds of the formula (1) ##STR1## wherein X and Y are each N or NH, Z is O or OH, (1) when X=N and Y=NH, Z=O, and *1 and *3 are double bonds, (2) when X=NH and Y=N, Z=O, and *2 and *3 are double bonds, (3) when X=N and Y=N, Z=OH, and *2 and *4 are double bonds, and R is a side chain derived from an amino acid; for example, the amino acid is glycine with R=H, alanine with R=CH.sub.3, glutamic acid with R=CH.sub.2 CH.sub.2 COOH, lysine with R=CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 NH.sub.2, or leucine with R=CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3, and/or an analogues thereof are useful for imparting a "thick, sour" taste to foods.Type: GrantFiled: July 31, 1997Date of Patent: August 3, 1999Assignee: Ajinomoto Co., Inc.Inventors: Keigo Shima, Tsutomu Harada, Eiichiro Suzuki, Yutaka Honda
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Patent number: 5853784Abstract: Volatile flavour molecules having a particular cyclic enolone structure are stabilised by complexation with alkaline earth metal ions. These complexes are stable until exposed to certain conditions of temperature and/or moisture.Type: GrantFiled: October 16, 1997Date of Patent: December 29, 1998Assignee: British-American Tobacco Company LimitedInventors: Marcos Pery Campos, Rosemary Elizabeth O'Reilly
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Patent number: 5783244Abstract: The invention relates to flavoring compositions characterized by an effective amount of gamma-jasmolactone having the formula ##STR1## as well as the use of these flavorings or gamma-jasmolactone per se for imparting, enhancing or improving the flavor, in particular the fruity character of foodstuffs and drinks.Type: GrantFiled: February 2, 1993Date of Patent: July 21, 1998Assignee: Unilever Patent Holdings B.V.Inventors: Anton Vlas, Hans Julius Wille
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Patent number: 5780090Abstract: Tripeptides containing a hydrophobic amino acid residue and at least one acidic amino acid residue, together with amino acid derivatives having a structure of the N-lactoyl-X type, where X represents an amino acid residue, are very useful flavoring ingredients for the preparation of flavoring compositions and flavored food products upon which they confer a remarkable fullness and mouthfeel.Type: GrantFiled: March 12, 1997Date of Patent: July 14, 1998Assignee: Firmenich SAInventors: Eric Frerot, Sina Dorothea Escher
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Patent number: 5756136Abstract: Encapsulation of a flavor or active agent in a matrix of whey protein yields an encapsulation composition which results in the controlled release of the flavor or active agent and which may be incorporated in a yeast-leavened dough without causing a deleterious effect on the rising of the dough.Type: GrantFiled: June 2, 1995Date of Patent: May 26, 1998Assignee: McCormick & Company, Inc.Inventors: Mark Black, Lewis M. Popplewell, Michael A. Porzio
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Patent number: 5688546Abstract: A seasoning composition containing food and an amino acid derivative that imparts a "thick, sour taste" to the food.Type: GrantFiled: July 19, 1995Date of Patent: November 18, 1997Assignee: Ajinomoto Co., Inc.Inventors: Keigo Shima, Tsutomu Harada, Eiichiro Suzuki, Yutaka Honda
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Patent number: 5676993Abstract: The present invention is directed to a means of enhancing the cocoa flavor to a fat matrix by adding thereto about 0.3 g to about 4.0 g phenylalanine, 0.75 g to about 2.0 g leucine, and about 0.5 g to about 3.0 g reducing sugar and optionally about 0.05 g to about 0.8 g alanine for each 100 g of unroasted fat matrix and roasting the same, and to the products produced therefrom.Type: GrantFiled: June 7, 1995Date of Patent: October 14, 1997Assignee: Hershey Foods CorporationInventors: Julia J. Watterson, Kenneth B. Miller, Joseph J. Furjanic, David A. Stuart
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Patent number: 5631038Abstract: Ingestible compounds which are substantially tasteless and which have been found to be effective reducers or eliminators of undesirable tastes for eatables.Type: GrantFiled: November 21, 1994Date of Patent: May 20, 1997Assignee: Bioresearch, Inc.Inventors: Robert J. Kurtz, William D. Fuller
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Patent number: 5580545Abstract: Taste modifier comprising a flavone derivative as an active ingredient of the general formula (I): ##STR1## wherein R.sub.1, R.sub.3, R.sub.4, R.sub.6 and R.sub.8 are independently a methoxy group or an hydrogen atom, R.sub.2 and R.sub.7 are methoxy groups, and R.sub.5 is a methoxy group or an hydroxy group, and a method of modifying taste, comprising adding a taste-modifying effective amount of the flavone derivative (I) to a product used in a mouth or an orally ingestible product. Various factors associated with taste can be modified, for example, the derivative can enhance sourness, reduce saltiness, inhibit unpleasant lasting of sweetness, enhance refreshing flavor and its continuity, reduce flavor associated with acetic acid, and enhance body, deliciousness and savor associated with the combination of these tastes.Type: GrantFiled: April 14, 1995Date of Patent: December 3, 1996Assignee: San-Ei Gen F.F.I., Inc.Inventors: Tsutomu Washino, Kazuhiko Oosaki, Masamitsu Moriwaki, Katsumasa Fujii, Chiyoki Yukawa, Tatsuo Akai, Kenshi Mitsunaga
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Patent number: 5545424Abstract: 4-(1-menthoxymethyl)-2-phenyl-1,3-dioxolane or a derivative thereof represented by formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom, a hydroxy group or a lower alkoxy group; R.sup.2 and R.sup.3, which may be the same or different, each represents a hydrogen atom, a hydroxy group, a lower alkoxy group, or, when taken together, R.sup.2 and R.sup.3 represent a methylene dioxy group; useful in flavor compositions.Type: GrantFiled: October 12, 1994Date of Patent: August 13, 1996Assignees: Takasago International Corporation, Takasago Institute For Interdisciplinary Science Inc.Inventors: Tetsuo Nakatsu, Carter B. Green, Gary A. Reitz, Raphael K. L. Kang
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Patent number: 5416069Abstract: Novel naphthofuran derivatives of the formula ##STR1## wherein R represents hydrogen, methyl or ethyl. The compounds of formula I are valuable (amber) odorants and also flavorants. Odorant and flavorant compositions employing (I) as well as processes for making them are also described.Type: GrantFiled: July 14, 1994Date of Patent: May 16, 1995Assignee: Givaudan-Roure CorporationInventor: Peter Naegeli
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Patent number: 5372834Abstract: Described is the use of one or more of the acids: aconitic acid, gluconic acid and/or succinic acid taken alone or further together with sclareolide in augmenting or enhancing the organoleptic properites of foodstuffs particularly with respect to imparting a umami effect and/or imparting of mouthfeel and fullness to the flavor of foodstuffs in the absence of amino acids except sulfur-bearing amino acids, salts thereof, pyrrolidone carboxylic acid, salts thereof and nucleotides.Type: GrantFiled: June 24, 1994Date of Patent: December 13, 1994Assignee: International Flavors & Fragances Inc.Inventors: Lawrence L. Buckholz, Jr., Lewis G. Scharpf
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Patent number: 5366747Abstract: Described is the use of one or more of the acids: aconitic acid, gluconic acid and/or succinic acid taken alone or further together with sclareolide in augmenting or enhancing the organoleptic properites of foodstuffs particularly with respect to imparting a umami effect and/or imparting of mouthfeel and fullness to the flavor of foodstuffs in the absence of amino acids except sulfur-bearing amino acids, salts thereof, pyrrolidone carboxylic acid, salts thereof and nucleotides.Type: GrantFiled: December 17, 1993Date of Patent: November 22, 1994Assignee: International Flavors & Fragrances Inc.Inventors: Lawrence L. Buckholz, Jr., Lewis G. Scharpf
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Patent number: 5277919Abstract: Chewing gum compositions having improved dipeptide-sweetener stability are provided. The chewing gums of the invention contain dipeptide sweetener(s) and at least one benzaldehyde acetal. Cherry-flavored and chocolate-cherry flavored chewing gums having improved dipeptide-sweetener stability are also provided.Type: GrantFiled: February 7, 1992Date of Patent: January 11, 1994Assignee: Wm. Wrigley Jr. CompanyInventors: Michael J. Greenberg, Sonya D. Johnson, Gordon N. McGrew
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Patent number: 5232735Abstract: Sweetness inhibitors which are substantially tasteless have been found to be bitter taste inhibitors or blockers. Conversely, bitter taste inhibitors which are substantially tasteless have been found to be sweet taste inhibitors or blockers.Type: GrantFiled: June 1, 1990Date of Patent: August 3, 1993Assignee: Bioresearch, Inc.Inventors: Robert J. Kurtz, William D. Fuller
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Patent number: 5179077Abstract: The invention concerns the novel compound, 4-methyl-3-pentyl-2 (5H)-furanone, I, a process for the manufacture of I and fragrance and flavor compositions containing I.Type: GrantFiled: September 27, 1991Date of Patent: January 12, 1993Assignee: Givaudan CorporationInventors: Peter M. Muller, Hans-Jakob Wild
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Patent number: 5167972Abstract: A chewing gum composition having improved stability of sweetener is disclosed. At least one cinnamic aldehyde acetal is substituted for cinnamic aldehyde in gums containing peptide sweeteners such as aspartame, alitame and combinations thereof. Of the acetals, most preferred is cinnamic aldehyde propylene glycol acetal. This acetal is particularly useful in cinnamon and fruit-flavored gums and especially in sugarless gum. Cinnamic aldehyde acetal is also added to other oral compositions, such as foods, drugs and toothpaste.Type: GrantFiled: September 4, 1990Date of Patent: December 1, 1992Assignee: Wm. Wrigley Jr. CompanyInventors: Michael J. Greenberg, Sonya D. Johnson
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Patent number: 5145703Abstract: The invention relates to new thio-alkanones of the formula ##STR1## in which X represents an oxygen or sulphur atom,R.sub.1 represents hydrogen or a C.sub.1 -C.sub.2 -alkyl group and the broken lines represent a single bond or no bond,to a process for their preparation and their use as flavorings.Type: GrantFiled: May 16, 1991Date of Patent: September 8, 1992Assignee: Haarmann & ReimerInventors: Roland Emberger, Matthias Gunter, Rudolf Hopp, Manfred Kopsel, Walter Kuhn, Peter Werkhoff
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Patent number: 5112803Abstract: Described is a process for the preparation of compositions of matter containing octalactones defined according to the structure: ##STR1## which includes the stereoisomers having the structures: ##STR2## by means of the sequential steps of (i) fermentation of caprylic acid or the ethyl ester of caprylic acid defined according to the generic structure: ##STR3## wherein R is hydrogen or ethyl using a microorganism selected from the group consisting of:Mortierella isabellina, ATCC 44583;Mortierella isabellina, ATCC 38063;Syncephalastrum racemosum, NRRL A-5889;Mortierella isabellina, IFO 7884;Mortierella ramanniana var. angulispora, IFO 8187;Mortierella isabellina, CBS 221.Type: GrantFiled: June 21, 1991Date of Patent: May 12, 1992Assignee: International Flavors & Fragrances Inc.Inventors: Mohamad I. Farbood, Lynda B. McLean, James A. Morris, Henry A. Bondarovich
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Patent number: 5079023Abstract: The use of acetals as aldehyde generators in foodstuff applications is disclosed.Type: GrantFiled: July 17, 1989Date of Patent: January 7, 1992Assignee: Hercules IncorporatedInventor: Robert S. DeSimone
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Patent number: 5045336Abstract: The sweetness of an ingestible product or oral composition containing a sweetening sugar or sugar alcohol in relatively large quantities can be reduced and thereby the flavor enhanced by incorporation of at least one compound of the general formula (I) ##STR1## in which m represents 0.Type: GrantFiled: May 14, 1986Date of Patent: September 3, 1991Assignee: Amstar Sugar CorporationInventors: Michael G. Lindley, Elner B. Rathbone
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Patent number: 5032513Abstract: A process for the preparation of gamma and delta lactones from organic carboxylic acids or derivatives thereof is disclosed. The process comprises cultivating, under aerobic conditions, a fungus of the genus Mucor in a suitable medium containing the carboxylic acid or a derivative thereof.Type: GrantFiled: June 1, 1988Date of Patent: July 16, 1991Assignee: BASF CorporationInventors: Gregory V. Page, Robert G. Eilerman
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Patent number: 5021402Abstract: Cyclic ethers of formula ##STR1## wherein the dotted line indicates the location of a single or double bond and the symbol R represents an isopropenyl radical or a 1-ethoxy-1-methylethyl radical, are novel compounds with useful organoleptic properties. They can be used as active ingredients in perfuming compositions and perfumed products to which they confer rosy-fruity type odor notes. In addition, they possess flavor qualities which render these compounds useful for flavoring foodstuffs and drinks and, namely, mango-type drinks.A process for the preparation of the compounds of formula (I) is also disclosed.Type: GrantFiled: November 21, 1989Date of Patent: June 4, 1991Assignee: Firmenich SAInventors: Anthony F. Morris, Regula Naef, Sina Escher, Alain Velluz
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Patent number: 4999207Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) the sweetness of foodstuffs and beverages sweetened with non-neutrative sweeteners, e.g., aspartame is enhanced by admixing with the non-neutrative sweetener, prior to addition to the beverage or foodstuff, sclareolide; and(iii) bitter nuances imnparted by the use of potassium chloride in salt substitutes are substantially covered by means of admixing salt substitutes with sclareolide.Type: GrantFiled: January 2, 1990Date of Patent: March 12, 1991Assignee: International Flavors & Fragrances Inc.Inventors: Lawrence Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf
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Patent number: 4988532Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) the sweetness of foodstuffs and beverages sweetened with non-neutrative sweeteners, e.g., aspartame is enhanced by admixing with the non-neutrative sweetener, prior to addition to the beverage or foodstuff, sclareolide; and(iii) bitter nuances imparted by the use of potassium chloride in salt substitutes are substantially covered by means of admixing such salt substitutes with sclareolide.Type: GrantFiled: August 7, 1990Date of Patent: January 29, 1991Assignee: International Flavors & Fragrances Inc.Inventors: Lawrence Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf
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Patent number: 4988527Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) sweetness of foodstuffs and beverages caused by non-neutrative sweeteners e.g.Type: GrantFiled: August 7, 1990Date of Patent: January 29, 1991Assignee: International Flavors & Fragrances Inc.Inventors: Lawrence L. Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf, Eugene W. Seitz
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Patent number: 4966783Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) the sweetness of foodstuffs and beverages sweetened with non-neutrative sweeteners, e.g., aspartame is enhanced by admixing with the non-neutrative sweetener, prior to addition to the beverage or foodstuff, sclareolide; and(iii) bitter nuances imparted by the use of potassium chloride in salt substitutes are substantially covered by means of admixing such salt substitutes with sclareolide.Type: GrantFiled: June 8, 1990Date of Patent: October 30, 1990Assignee: International Flavors & Fragrances Inc.Inventors: Lawrence Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf
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Patent number: 4960597Abstract: Described is a process for the preparation of compositions of matter containing unsaturated lactones defined according to the generic structure: ##STR1## wherein R represents C.sub.6 alkyl or alkenyl; and X represents C.sub.2, C.sub.4 or C.sub.6 alkylene or alkenylene; with the provisos that R is C.sub.6 alkyl when X is alkenylene and R is C.sub.6 alkenyl when X is alkylene by means of the sequential steps of (i) fermentation of castor oil or ricinoleic acid using a microorganism selected from the group consisting of:Candida petrophilum, ATCC 20226;Candida oleophila, ATCC 20177;Candida sp., ATCC 20504; andCandida sake, ATCC 28137whereby gamma hydroxydecanoic acid and a mixture of other acids defined according to the generic structure: ##STR2## is formed wherein Y represents an oxo-saturated, oxo-unsaturated or di-unsaturated C.sub.9, C.sub.11 or C.sub.Type: GrantFiled: December 2, 1988Date of Patent: October 2, 1990Assignee: International Flavors & Fragrances Inc.Inventors: Mohamad I. Farbood, James A. Morris, Mark A. Sprecker, Lynda J. Bienkowski, Kevin P. Miller, Manfred H. Vock, Myrna L. Hagedorn
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Patent number: 4960603Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) sweetness of foodstuffs and beverages caused by non-neutrative sweetners e.g.Type: GrantFiled: June 8, 1990Date of Patent: October 2, 1990Assignee: International Flavors & Fragrances Inc.Inventors: Lawrence L. Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf, Eugene W. Seitz
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Patent number: 4950495Abstract: Described is the tetrahydro-5-isopropyl-2-methyl-2-thiophene acetonitrile of our invention having the structure: ##STR1## and organoleptic uses thereof in augmenting or enhancing the aroma or taste of perfume compositions, colognes, perfumed articles, foodstuffs and chewing gums.Type: GrantFiled: July 14, 1989Date of Patent: August 21, 1990Assignee: International Flavors & Fragrances Inc.Inventors: Richard M. Boden, Joseph A. McGhie
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Patent number: 4927652Abstract: The present invention is concerned with a process for the extraction of lactones from a lactone-containing lipid material, by contracting a medium, having a temperature near the critical temperature of the medium, and having a pressure near the critical pressure of the medium, with the lipid material, and subsequently removing the medium, wherein the medium, upon contacting, has a temperature T (in .degree.C.), and pressure P (in bar), such that:-25<=T* <=18.5-40<=P* <=300T*xP*<=1900where T*=T-Tc, P*=P-P.sub.c, T.sub.c is the critical temperature (in .degree.C.), and P.sub.c is the critical pressure (in bar) of the medium. Under the extraction conditions as applied in the process according to the present invention a low yield, combined with a high selectivity is obtained, resulting in a relatively small extracted fraction, which is substantially enriched in lactones.Type: GrantFiled: December 13, 1988Date of Patent: May 22, 1990Assignee: Lever Brothers CompanyInventor: Petrus G. M. Haring
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Patent number: 4917913Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) the sweetness of foodstuffs and beverages sweetened with non-neutrative sweeteners, e.g., aspartame is enhanced by admixing with the non-neutrative sweetener, prior to addition to the beverage or foodstuff, sclareolide; and(iii) bitter nuances imparted by the use of potassium chloride in salt substitutes are substantially covered by means of admixing such salt substitutes with sclareolide.Type: GrantFiled: September 29, 1989Date of Patent: April 17, 1990Assignee: International Flavors & Fragrances Inc.Inventors: Lawrence Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf
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Patent number: 4900740Abstract: N,N'-disubstituted guanidines containing a tetrazolyl or glycine moiety are provided as high potency sweetening agents.Type: GrantFiled: October 2, 1987Date of Patent: February 13, 1990Assignee: The NutraSweet CompanyInventors: George W. Muller, Eric Walters, Grant DuBois
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Patent number: 4889735Abstract: Furanic esters of formula ##STR1## wherein R designates a linear or branched, saturated or unsaturated C.sub.2 -C.sub.6 alkyl radical, are novel compounds having useful organoleptic properties and, consequently, can be used advantageously in the manufacture of flavor compositions, and in the aromatization of foodstuffs, beverages, pharmaceutical preparations and tobacco products.Type: GrantFiled: August 8, 1988Date of Patent: December 26, 1989Assignee: Firmenich S.A.Inventors: Wilhelm Pickenhagen, Alain Velluz
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Patent number: 4889736Abstract: The present invention is concerned with a flavor concentrate containing a precursor of biacetyl, which concentrate is characterized in that it contains 0.1-99 wt. % precursor compound(s) having the following structural formula: ##STR1## in which X is ##STR2## and in which R.sub.1, R.sub.2, R.sub.5 and R.sub.6 can differ from each other or can be identical and consist of a methyl or ethyl group.It has been found that the present precursor compounds release biacetyl upon heating. By using the present precursor compounds in food products problems attached to the use of very volatile diketones in food products may be overcome.Type: GrantFiled: May 10, 1988Date of Patent: December 26, 1989Assignee: Lever Brothers CompanyInventors: Tamme S. M. Doornbos, Petrus Haring, Arnoldus Van Der Heijden
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Patent number: 4883884Abstract: Described is the tetrahydro-5-isopropyl-2-methyl-thiophene acetonitrile of our invention having the structure: ##STR1## and organoleptic uses thereof in augmenting or enhancing the aroma or taste of perfume compositions, colognes, perfumed articles, foodstuffs and chewing gums.Type: GrantFiled: November 18, 1988Date of Patent: November 28, 1989Assignee: International Flavors & Fragrances Inc.Inventors: Richard M. Boden, Joseph A. McGhie
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Patent number: 4880641Abstract: A compound of the general formula, ##STR1## wherein R.sub.1 and R.sub.2 independently are --H, --CH.sub.3, or --CH.sub.2 CH.sub.3 ; and R.sub.3 is alkyl of from 1 to 10 carbons or aryl of from 6 to 10 carbons.Type: GrantFiled: May 6, 1988Date of Patent: November 14, 1989Assignee: Hercules IncorporatedInventors: Brian Byrne, Louise M. L. Lawter
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Patent number: 4758680Abstract: A compound of the general formula, ##STR1## wherein R.sub.1 and R.sub.2 independently are --H, --CH.sub.3, or --CH.sub.2 CH.sub.3 ; and R.sub.3 is alkyl of from 1 to 10 carbons or aryl of from 6 to 10 carbons.Type: GrantFiled: November 9, 1987Date of Patent: July 19, 1988Assignee: Hercules IncorporatedInventors: Brian Byrne, Louise M. L. Lawter
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Patent number: 4671959Abstract: Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of:(i) Nutmeg Oil;(ii) Mace Extract;(iii) Neroli Oil;(iv) Valerian Oil;(v) Myristicin;(vi) Isoelemicin; and(vii) Elemicin.Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfumed article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.Type: GrantFiled: May 2, 1986Date of Patent: June 9, 1987Assignees: Yale University, International Flavors & Fragrances Inc.Inventors: Craig B. Warren, Marina A. Munteanu, Gary E. Schwartz, Carlos Benaim, Henry G. Walter, Jr., Ronald S. Leight, Donald A. Withycombe, Braja D. Mookherjee, Robert W. Trenkle
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Patent number: 4670463Abstract: Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of:(i) Nutmeg Oil;(ii) Mace Extract;(iii) Neroli Oil;(iv) Valerian Oil;(v) Myristicin;(vi) Isoelemicin; and(vii) Elemicin.Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfume article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.Type: GrantFiled: May 2, 1986Date of Patent: June 2, 1987Assignees: Yale University, International Flavors & Fragrances Inc.Inventors: Craig B. Warren, Marina A. Munteanu, Gary E. Schwartz, Carlos Benaim, Henry G. Walter, Jr., Ronald S. Leight, Donald A. Withycombe, Braja D. Mookherjee, Robert W. Trenkle
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Patent number: 4670264Abstract: Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of:(i) Nutmeg Oil;(ii) Mace Extract;(iii) Neroli Oil;(iv) Valerian Oil;(v) Myristicin;(vi) Isoelemicin; and(vii) Elemicin.Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfumed article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.Type: GrantFiled: November 21, 1985Date of Patent: June 2, 1987Assignees: International Flavors & Fragrances Inc., Yale UniversityInventors: Craig B. Warren, Marina A. Munteanu, Gary E. Schwartz, Carlos Benaim, Henry G. Walter, Jr., Ronald S. Leight, Donald A. Withycombe, Braja D. Mookherjee, Robert W. Trenkle
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Patent number: 4642240Abstract: Food acceptable sweetness modifying compounds comprising certain aromatic amino acids and foodstuff compositions containing the same.Type: GrantFiled: March 25, 1985Date of Patent: February 10, 1987Assignee: General Foods CorporationInventors: Ronald E. Barnett, Ronald G. Yarger
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Patent number: 4634548Abstract: The invention is concerned with novel bicyclic epoxides, a process for their manufacture and novel fragrance and flavor compositions containing the same.Type: GrantFiled: January 9, 1984Date of Patent: January 6, 1987Assignee: Givaudan CorporationInventors: Daniel Helmlinger, Mario Pesaro
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Patent number: 4590284Abstract: A compound of the general formula, ##STR1## wherein R.sub.1 and R.sub.2 independently are --H, --CH.sub.3, or --CH.sub.2 CH.sub.3 ; and R.sub.3 and R.sub.4 are independently alkyl or alkenyl of from 1 to 10 carbons, or aryl of from 6 to 10 carbons, or R.sub.4 =hydrogen.Type: GrantFiled: April 29, 1985Date of Patent: May 20, 1986Assignee: Hercules IncorporatedInventors: Brian Byrne, Louise M. L. Lawter
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Patent number: 4571345Abstract: Compounds of the formula: ##STR1## wherein n is 0 or 1, R is lower alkyl (substituted or unsubstituted), R' is H or lower alkyl, and R" is a branched alkyl, alkyl-cycloalkyl, cycloalkyl, polycycloalkyl (poly=2 or more, fused or non-fused), phenyl or alkyl-substituted phenyl, and physiologically acceptable cationic and acid addition salts thereof, which compounds are potent sweeteners. These derivatives of gem-diaminoalkanes are many times sweeter than sugar and are free from undesirable flavor qualities. Furthermore, they possess an unanticipated high degree of solubility compared with known synthetic sweeteners. In addition, the compounds possess high stability so that they can be used in all types of beverages and in conventional food processing. Sweetening compositions and sweetened edible compositions of these compounds are also provided.Type: GrantFiled: June 13, 1983Date of Patent: February 18, 1986Assignee: Cumberland Packing Corp.Inventors: Michael S. Verlander, William D. Fuller, Murray Goodman
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Patent number: 4570648Abstract: Novel esters, of the general formula ##STR1## wherein R represents C.sub.1-4 -alkyl or C.sub.2-4 -alkenyl and one of the three broken lines represents an additional bond,are disclosed. Also disclosed are novel odorant and/or flavouring compositions containing esters or formula I, a process and intermediates for the manufacture of the esters of formula I and the use of esters of formula I as odorant and/or flavouring substances.Type: GrantFiled: September 7, 1982Date of Patent: February 18, 1986Assignee: Givaudan CorporationInventor: Hanspeter Schenk
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Patent number: 4568470Abstract: Described for use in augmenting or enhancing the aroma or taste of consumable materials including perfume compositions, colognes and perfumed articles, foodstuffs, chewing gums, toothpastes and medicinal products are the cis and/or trans isomers of the macrocyclic lactone defined according to the structure: ##STR1## produced according to the process of first reacting the ester defined according to the structure: ##STR2## with the alkenol having the structure: ##STR3## in order to produce the di-unsaturated ester having the structure: ##STR4## and then causing the said diester to undergo an internal metathesis to form the compound having the structure: ##STR5##Type: GrantFiled: January 15, 1985Date of Patent: February 4, 1986Assignee: International Flavors & Fragrances Inc.Inventors: Augustinus G. Van Loveren, Marie R. Hanna, Domenick Luccarelli, Jr., David R. Bowen, Manfred H. Vock, Wilhelmus J. Wiegers
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Patent number: 4549029Abstract: Novel substituted tetrahydrofurans having a six-membered ring in the 4 position and methyl substituents in the 2 and 4 positions possess organoleptic properties described as fruity, citrus-like and reminiscent of grapefruit. These compounds are useful in fragrances and flavors.Type: GrantFiled: April 5, 1983Date of Patent: October 22, 1985Assignee: Givaudan CorporationInventor: Alan R. Hochstetler
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Patent number: 4537702Abstract: Perfume and flavoring compositions, perfumed articles and materials respectively flavored foods, drugs, toothpaste, and tobacco products containing 10-isopropyl-2.7-dimethyl-oxaspiro[4.5]deca-3.6-diene having formula ##STR1## as essential compound for imparting thereto an olfactive note of the cassis type as well as this compound per se.Type: GrantFiled: May 10, 1983Date of Patent: August 27, 1985Assignee: Naarden International N.V.Inventors: Antonius J. A. van der Weerdt, Harrie Renes
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Patent number: 4522765Abstract: Described is di(7-octenyl) carbonate having the structure: ##STR1## and the use thereof as an intermediate in producing the compound having the structure: ##STR2## useful in perfumery.Type: GrantFiled: June 22, 1984Date of Patent: June 11, 1985Assignee: International Flavors & Fragrances Inc.Inventors: Wilhelmus J. Wiegers, Augustinus G. Van Loveren, Marie R. Hanna, Domenick Luccarelli, Jr., David R. Bowen, Manfred H. Vock