Heterocyclic Patents (Class 426/536)
  • Patent number: 5932267
    Abstract: Compounds of the formula (1) ##STR1## wherein X and Y are each N or NH, Z is O or OH, (1) when X=N and Y=NH, Z=O, and *1 and *3 are double bonds, (2) when X=NH and Y=N, Z=O, and *2 and *3 are double bonds, (3) when X=N and Y=N, Z=OH, and *2 and *4 are double bonds, and R is a side chain derived from an amino acid; for example, the amino acid is glycine with R=H, alanine with R=CH.sub.3, glutamic acid with R=CH.sub.2 CH.sub.2 COOH, lysine with R=CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 NH.sub.2, or leucine with R=CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3, and/or an analogues thereof are useful for imparting a "thick, sour" taste to foods.
    Type: Grant
    Filed: July 31, 1997
    Date of Patent: August 3, 1999
    Assignee: Ajinomoto Co., Inc.
    Inventors: Keigo Shima, Tsutomu Harada, Eiichiro Suzuki, Yutaka Honda
  • Patent number: 5853784
    Abstract: Volatile flavour molecules having a particular cyclic enolone structure are stabilised by complexation with alkaline earth metal ions. These complexes are stable until exposed to certain conditions of temperature and/or moisture.
    Type: Grant
    Filed: October 16, 1997
    Date of Patent: December 29, 1998
    Assignee: British-American Tobacco Company Limited
    Inventors: Marcos Pery Campos, Rosemary Elizabeth O'Reilly
  • Patent number: 5783244
    Abstract: The invention relates to flavoring compositions characterized by an effective amount of gamma-jasmolactone having the formula ##STR1## as well as the use of these flavorings or gamma-jasmolactone per se for imparting, enhancing or improving the flavor, in particular the fruity character of foodstuffs and drinks.
    Type: Grant
    Filed: February 2, 1993
    Date of Patent: July 21, 1998
    Assignee: Unilever Patent Holdings B.V.
    Inventors: Anton Vlas, Hans Julius Wille
  • Patent number: 5780090
    Abstract: Tripeptides containing a hydrophobic amino acid residue and at least one acidic amino acid residue, together with amino acid derivatives having a structure of the N-lactoyl-X type, where X represents an amino acid residue, are very useful flavoring ingredients for the preparation of flavoring compositions and flavored food products upon which they confer a remarkable fullness and mouthfeel.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: July 14, 1998
    Assignee: Firmenich SA
    Inventors: Eric Frerot, Sina Dorothea Escher
  • Patent number: 5756136
    Abstract: Encapsulation of a flavor or active agent in a matrix of whey protein yields an encapsulation composition which results in the controlled release of the flavor or active agent and which may be incorporated in a yeast-leavened dough without causing a deleterious effect on the rising of the dough.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: May 26, 1998
    Assignee: McCormick & Company, Inc.
    Inventors: Mark Black, Lewis M. Popplewell, Michael A. Porzio
  • Patent number: 5688546
    Abstract: A seasoning composition containing food and an amino acid derivative that imparts a "thick, sour taste" to the food.
    Type: Grant
    Filed: July 19, 1995
    Date of Patent: November 18, 1997
    Assignee: Ajinomoto Co., Inc.
    Inventors: Keigo Shima, Tsutomu Harada, Eiichiro Suzuki, Yutaka Honda
  • Patent number: 5676993
    Abstract: The present invention is directed to a means of enhancing the cocoa flavor to a fat matrix by adding thereto about 0.3 g to about 4.0 g phenylalanine, 0.75 g to about 2.0 g leucine, and about 0.5 g to about 3.0 g reducing sugar and optionally about 0.05 g to about 0.8 g alanine for each 100 g of unroasted fat matrix and roasting the same, and to the products produced therefrom.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 14, 1997
    Assignee: Hershey Foods Corporation
    Inventors: Julia J. Watterson, Kenneth B. Miller, Joseph J. Furjanic, David A. Stuart
  • Patent number: 5631038
    Abstract: Ingestible compounds which are substantially tasteless and which have been found to be effective reducers or eliminators of undesirable tastes for eatables.
    Type: Grant
    Filed: November 21, 1994
    Date of Patent: May 20, 1997
    Assignee: Bioresearch, Inc.
    Inventors: Robert J. Kurtz, William D. Fuller
  • Patent number: 5580545
    Abstract: Taste modifier comprising a flavone derivative as an active ingredient of the general formula (I): ##STR1## wherein R.sub.1, R.sub.3, R.sub.4, R.sub.6 and R.sub.8 are independently a methoxy group or an hydrogen atom, R.sub.2 and R.sub.7 are methoxy groups, and R.sub.5 is a methoxy group or an hydroxy group, and a method of modifying taste, comprising adding a taste-modifying effective amount of the flavone derivative (I) to a product used in a mouth or an orally ingestible product. Various factors associated with taste can be modified, for example, the derivative can enhance sourness, reduce saltiness, inhibit unpleasant lasting of sweetness, enhance refreshing flavor and its continuity, reduce flavor associated with acetic acid, and enhance body, deliciousness and savor associated with the combination of these tastes.
    Type: Grant
    Filed: April 14, 1995
    Date of Patent: December 3, 1996
    Assignee: San-Ei Gen F.F.I., Inc.
    Inventors: Tsutomu Washino, Kazuhiko Oosaki, Masamitsu Moriwaki, Katsumasa Fujii, Chiyoki Yukawa, Tatsuo Akai, Kenshi Mitsunaga
  • Patent number: 5545424
    Abstract: 4-(1-menthoxymethyl)-2-phenyl-1,3-dioxolane or a derivative thereof represented by formula (I): ##STR1## wherein R.sup.1 represents a hydrogen atom, a hydroxy group or a lower alkoxy group; R.sup.2 and R.sup.3, which may be the same or different, each represents a hydrogen atom, a hydroxy group, a lower alkoxy group, or, when taken together, R.sup.2 and R.sup.3 represent a methylene dioxy group; useful in flavor compositions.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: August 13, 1996
    Assignees: Takasago International Corporation, Takasago Institute For Interdisciplinary Science Inc.
    Inventors: Tetsuo Nakatsu, Carter B. Green, Gary A. Reitz, Raphael K. L. Kang
  • Patent number: 5416069
    Abstract: Novel naphthofuran derivatives of the formula ##STR1## wherein R represents hydrogen, methyl or ethyl. The compounds of formula I are valuable (amber) odorants and also flavorants. Odorant and flavorant compositions employing (I) as well as processes for making them are also described.
    Type: Grant
    Filed: July 14, 1994
    Date of Patent: May 16, 1995
    Assignee: Givaudan-Roure Corporation
    Inventor: Peter Naegeli
  • Patent number: 5372834
    Abstract: Described is the use of one or more of the acids: aconitic acid, gluconic acid and/or succinic acid taken alone or further together with sclareolide in augmenting or enhancing the organoleptic properites of foodstuffs particularly with respect to imparting a umami effect and/or imparting of mouthfeel and fullness to the flavor of foodstuffs in the absence of amino acids except sulfur-bearing amino acids, salts thereof, pyrrolidone carboxylic acid, salts thereof and nucleotides.
    Type: Grant
    Filed: June 24, 1994
    Date of Patent: December 13, 1994
    Assignee: International Flavors & Fragances Inc.
    Inventors: Lawrence L. Buckholz, Jr., Lewis G. Scharpf
  • Patent number: 5366747
    Abstract: Described is the use of one or more of the acids: aconitic acid, gluconic acid and/or succinic acid taken alone or further together with sclareolide in augmenting or enhancing the organoleptic properites of foodstuffs particularly with respect to imparting a umami effect and/or imparting of mouthfeel and fullness to the flavor of foodstuffs in the absence of amino acids except sulfur-bearing amino acids, salts thereof, pyrrolidone carboxylic acid, salts thereof and nucleotides.
    Type: Grant
    Filed: December 17, 1993
    Date of Patent: November 22, 1994
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Lawrence L. Buckholz, Jr., Lewis G. Scharpf
  • Patent number: 5277919
    Abstract: Chewing gum compositions having improved dipeptide-sweetener stability are provided. The chewing gums of the invention contain dipeptide sweetener(s) and at least one benzaldehyde acetal. Cherry-flavored and chocolate-cherry flavored chewing gums having improved dipeptide-sweetener stability are also provided.
    Type: Grant
    Filed: February 7, 1992
    Date of Patent: January 11, 1994
    Assignee: Wm. Wrigley Jr. Company
    Inventors: Michael J. Greenberg, Sonya D. Johnson, Gordon N. McGrew
  • Patent number: 5232735
    Abstract: Sweetness inhibitors which are substantially tasteless have been found to be bitter taste inhibitors or blockers. Conversely, bitter taste inhibitors which are substantially tasteless have been found to be sweet taste inhibitors or blockers.
    Type: Grant
    Filed: June 1, 1990
    Date of Patent: August 3, 1993
    Assignee: Bioresearch, Inc.
    Inventors: Robert J. Kurtz, William D. Fuller
  • Patent number: 5179077
    Abstract: The invention concerns the novel compound, 4-methyl-3-pentyl-2 (5H)-furanone, I, a process for the manufacture of I and fragrance and flavor compositions containing I.
    Type: Grant
    Filed: September 27, 1991
    Date of Patent: January 12, 1993
    Assignee: Givaudan Corporation
    Inventors: Peter M. Muller, Hans-Jakob Wild
  • Patent number: 5167972
    Abstract: A chewing gum composition having improved stability of sweetener is disclosed. At least one cinnamic aldehyde acetal is substituted for cinnamic aldehyde in gums containing peptide sweeteners such as aspartame, alitame and combinations thereof. Of the acetals, most preferred is cinnamic aldehyde propylene glycol acetal. This acetal is particularly useful in cinnamon and fruit-flavored gums and especially in sugarless gum. Cinnamic aldehyde acetal is also added to other oral compositions, such as foods, drugs and toothpaste.
    Type: Grant
    Filed: September 4, 1990
    Date of Patent: December 1, 1992
    Assignee: Wm. Wrigley Jr. Company
    Inventors: Michael J. Greenberg, Sonya D. Johnson
  • Patent number: 5145703
    Abstract: The invention relates to new thio-alkanones of the formula ##STR1## in which X represents an oxygen or sulphur atom,R.sub.1 represents hydrogen or a C.sub.1 -C.sub.2 -alkyl group and the broken lines represent a single bond or no bond,to a process for their preparation and their use as flavorings.
    Type: Grant
    Filed: May 16, 1991
    Date of Patent: September 8, 1992
    Assignee: Haarmann & Reimer
    Inventors: Roland Emberger, Matthias Gunter, Rudolf Hopp, Manfred Kopsel, Walter Kuhn, Peter Werkhoff
  • Patent number: 5112803
    Abstract: Described is a process for the preparation of compositions of matter containing octalactones defined according to the structure: ##STR1## which includes the stereoisomers having the structures: ##STR2## by means of the sequential steps of (i) fermentation of caprylic acid or the ethyl ester of caprylic acid defined according to the generic structure: ##STR3## wherein R is hydrogen or ethyl using a microorganism selected from the group consisting of:Mortierella isabellina, ATCC 44583;Mortierella isabellina, ATCC 38063;Syncephalastrum racemosum, NRRL A-5889;Mortierella isabellina, IFO 7884;Mortierella ramanniana var. angulispora, IFO 8187;Mortierella isabellina, CBS 221.
    Type: Grant
    Filed: June 21, 1991
    Date of Patent: May 12, 1992
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Mohamad I. Farbood, Lynda B. McLean, James A. Morris, Henry A. Bondarovich
  • Patent number: 5079023
    Abstract: The use of acetals as aldehyde generators in foodstuff applications is disclosed.
    Type: Grant
    Filed: July 17, 1989
    Date of Patent: January 7, 1992
    Assignee: Hercules Incorporated
    Inventor: Robert S. DeSimone
  • Patent number: 5045336
    Abstract: The sweetness of an ingestible product or oral composition containing a sweetening sugar or sugar alcohol in relatively large quantities can be reduced and thereby the flavor enhanced by incorporation of at least one compound of the general formula (I) ##STR1## in which m represents 0.
    Type: Grant
    Filed: May 14, 1986
    Date of Patent: September 3, 1991
    Assignee: Amstar Sugar Corporation
    Inventors: Michael G. Lindley, Elner B. Rathbone
  • Patent number: 5032513
    Abstract: A process for the preparation of gamma and delta lactones from organic carboxylic acids or derivatives thereof is disclosed. The process comprises cultivating, under aerobic conditions, a fungus of the genus Mucor in a suitable medium containing the carboxylic acid or a derivative thereof.
    Type: Grant
    Filed: June 1, 1988
    Date of Patent: July 16, 1991
    Assignee: BASF Corporation
    Inventors: Gregory V. Page, Robert G. Eilerman
  • Patent number: 5021402
    Abstract: Cyclic ethers of formula ##STR1## wherein the dotted line indicates the location of a single or double bond and the symbol R represents an isopropenyl radical or a 1-ethoxy-1-methylethyl radical, are novel compounds with useful organoleptic properties. They can be used as active ingredients in perfuming compositions and perfumed products to which they confer rosy-fruity type odor notes. In addition, they possess flavor qualities which render these compounds useful for flavoring foodstuffs and drinks and, namely, mango-type drinks.A process for the preparation of the compounds of formula (I) is also disclosed.
    Type: Grant
    Filed: November 21, 1989
    Date of Patent: June 4, 1991
    Assignee: Firmenich SA
    Inventors: Anthony F. Morris, Regula Naef, Sina Escher, Alain Velluz
  • Patent number: 4999207
    Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) the sweetness of foodstuffs and beverages sweetened with non-neutrative sweeteners, e.g., aspartame is enhanced by admixing with the non-neutrative sweetener, prior to addition to the beverage or foodstuff, sclareolide; and(iii) bitter nuances imnparted by the use of potassium chloride in salt substitutes are substantially covered by means of admixing salt substitutes with sclareolide.
    Type: Grant
    Filed: January 2, 1990
    Date of Patent: March 12, 1991
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Lawrence Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf
  • Patent number: 4988532
    Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) the sweetness of foodstuffs and beverages sweetened with non-neutrative sweeteners, e.g., aspartame is enhanced by admixing with the non-neutrative sweetener, prior to addition to the beverage or foodstuff, sclareolide; and(iii) bitter nuances imparted by the use of potassium chloride in salt substitutes are substantially covered by means of admixing such salt substitutes with sclareolide.
    Type: Grant
    Filed: August 7, 1990
    Date of Patent: January 29, 1991
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Lawrence Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf
  • Patent number: 4988527
    Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) sweetness of foodstuffs and beverages caused by non-neutrative sweeteners e.g.
    Type: Grant
    Filed: August 7, 1990
    Date of Patent: January 29, 1991
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Lawrence L. Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf, Eugene W. Seitz
  • Patent number: 4966783
    Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) the sweetness of foodstuffs and beverages sweetened with non-neutrative sweeteners, e.g., aspartame is enhanced by admixing with the non-neutrative sweetener, prior to addition to the beverage or foodstuff, sclareolide; and(iii) bitter nuances imparted by the use of potassium chloride in salt substitutes are substantially covered by means of admixing such salt substitutes with sclareolide.
    Type: Grant
    Filed: June 8, 1990
    Date of Patent: October 30, 1990
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Lawrence Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf
  • Patent number: 4960597
    Abstract: Described is a process for the preparation of compositions of matter containing unsaturated lactones defined according to the generic structure: ##STR1## wherein R represents C.sub.6 alkyl or alkenyl; and X represents C.sub.2, C.sub.4 or C.sub.6 alkylene or alkenylene; with the provisos that R is C.sub.6 alkyl when X is alkenylene and R is C.sub.6 alkenyl when X is alkylene by means of the sequential steps of (i) fermentation of castor oil or ricinoleic acid using a microorganism selected from the group consisting of:Candida petrophilum, ATCC 20226;Candida oleophila, ATCC 20177;Candida sp., ATCC 20504; andCandida sake, ATCC 28137whereby gamma hydroxydecanoic acid and a mixture of other acids defined according to the generic structure: ##STR2## is formed wherein Y represents an oxo-saturated, oxo-unsaturated or di-unsaturated C.sub.9, C.sub.11 or C.sub.
    Type: Grant
    Filed: December 2, 1988
    Date of Patent: October 2, 1990
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Mohamad I. Farbood, James A. Morris, Mark A. Sprecker, Lynda J. Bienkowski, Kevin P. Miller, Manfred H. Vock, Myrna L. Hagedorn
  • Patent number: 4960603
    Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) sweetness of foodstuffs and beverages caused by non-neutrative sweetners e.g.
    Type: Grant
    Filed: June 8, 1990
    Date of Patent: October 2, 1990
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Lawrence L. Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf, Eugene W. Seitz
  • Patent number: 4950495
    Abstract: Described is the tetrahydro-5-isopropyl-2-methyl-2-thiophene acetonitrile of our invention having the structure: ##STR1## and organoleptic uses thereof in augmenting or enhancing the aroma or taste of perfume compositions, colognes, perfumed articles, foodstuffs and chewing gums.
    Type: Grant
    Filed: July 14, 1989
    Date of Patent: August 21, 1990
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Richard M. Boden, Joseph A. McGhie
  • Patent number: 4927652
    Abstract: The present invention is concerned with a process for the extraction of lactones from a lactone-containing lipid material, by contracting a medium, having a temperature near the critical temperature of the medium, and having a pressure near the critical pressure of the medium, with the lipid material, and subsequently removing the medium, wherein the medium, upon contacting, has a temperature T (in .degree.C.), and pressure P (in bar), such that:-25<=T* <=18.5-40<=P* <=300T*xP*<=1900where T*=T-Tc, P*=P-P.sub.c, T.sub.c is the critical temperature (in .degree.C.), and P.sub.c is the critical pressure (in bar) of the medium. Under the extraction conditions as applied in the process according to the present invention a low yield, combined with a high selectivity is obtained, resulting in a relatively small extracted fraction, which is substantially enriched in lactones.
    Type: Grant
    Filed: December 13, 1988
    Date of Patent: May 22, 1990
    Assignee: Lever Brothers Company
    Inventor: Petrus G. M. Haring
  • Patent number: 4917913
    Abstract: Described is the use of sclareolide in augmenting or enhancing the organoleptic properties of foodstuffs whereby:(i) richness and creaminess is added to low fat ice cream by admixing therewith the sclareolide;(ii) the sweetness of foodstuffs and beverages sweetened with non-neutrative sweeteners, e.g., aspartame is enhanced by admixing with the non-neutrative sweetener, prior to addition to the beverage or foodstuff, sclareolide; and(iii) bitter nuances imparted by the use of potassium chloride in salt substitutes are substantially covered by means of admixing such salt substitutes with sclareolide.
    Type: Grant
    Filed: September 29, 1989
    Date of Patent: April 17, 1990
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Lawrence Buckholz, Jr., Mohamad I. Farbood, Nicolas Kossiakoff, Lewis G. Scharpf
  • Patent number: 4900740
    Abstract: N,N'-disubstituted guanidines containing a tetrazolyl or glycine moiety are provided as high potency sweetening agents.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: February 13, 1990
    Assignee: The NutraSweet Company
    Inventors: George W. Muller, Eric Walters, Grant DuBois
  • Patent number: 4889735
    Abstract: Furanic esters of formula ##STR1## wherein R designates a linear or branched, saturated or unsaturated C.sub.2 -C.sub.6 alkyl radical, are novel compounds having useful organoleptic properties and, consequently, can be used advantageously in the manufacture of flavor compositions, and in the aromatization of foodstuffs, beverages, pharmaceutical preparations and tobacco products.
    Type: Grant
    Filed: August 8, 1988
    Date of Patent: December 26, 1989
    Assignee: Firmenich S.A.
    Inventors: Wilhelm Pickenhagen, Alain Velluz
  • Patent number: 4889736
    Abstract: The present invention is concerned with a flavor concentrate containing a precursor of biacetyl, which concentrate is characterized in that it contains 0.1-99 wt. % precursor compound(s) having the following structural formula: ##STR1## in which X is ##STR2## and in which R.sub.1, R.sub.2, R.sub.5 and R.sub.6 can differ from each other or can be identical and consist of a methyl or ethyl group.It has been found that the present precursor compounds release biacetyl upon heating. By using the present precursor compounds in food products problems attached to the use of very volatile diketones in food products may be overcome.
    Type: Grant
    Filed: May 10, 1988
    Date of Patent: December 26, 1989
    Assignee: Lever Brothers Company
    Inventors: Tamme S. M. Doornbos, Petrus Haring, Arnoldus Van Der Heijden
  • Patent number: 4883884
    Abstract: Described is the tetrahydro-5-isopropyl-2-methyl-thiophene acetonitrile of our invention having the structure: ##STR1## and organoleptic uses thereof in augmenting or enhancing the aroma or taste of perfume compositions, colognes, perfumed articles, foodstuffs and chewing gums.
    Type: Grant
    Filed: November 18, 1988
    Date of Patent: November 28, 1989
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Richard M. Boden, Joseph A. McGhie
  • Patent number: 4880641
    Abstract: A compound of the general formula, ##STR1## wherein R.sub.1 and R.sub.2 independently are --H, --CH.sub.3, or --CH.sub.2 CH.sub.3 ; and R.sub.3 is alkyl of from 1 to 10 carbons or aryl of from 6 to 10 carbons.
    Type: Grant
    Filed: May 6, 1988
    Date of Patent: November 14, 1989
    Assignee: Hercules Incorporated
    Inventors: Brian Byrne, Louise M. L. Lawter
  • Patent number: 4758680
    Abstract: A compound of the general formula, ##STR1## wherein R.sub.1 and R.sub.2 independently are --H, --CH.sub.3, or --CH.sub.2 CH.sub.3 ; and R.sub.3 is alkyl of from 1 to 10 carbons or aryl of from 6 to 10 carbons.
    Type: Grant
    Filed: November 9, 1987
    Date of Patent: July 19, 1988
    Assignee: Hercules Incorporated
    Inventors: Brian Byrne, Louise M. L. Lawter
  • Patent number: 4671959
    Abstract: Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of:(i) Nutmeg Oil;(ii) Mace Extract;(iii) Neroli Oil;(iv) Valerian Oil;(v) Myristicin;(vi) Isoelemicin; and(vii) Elemicin.Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfumed article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.
    Type: Grant
    Filed: May 2, 1986
    Date of Patent: June 9, 1987
    Assignees: Yale University, International Flavors & Fragrances Inc.
    Inventors: Craig B. Warren, Marina A. Munteanu, Gary E. Schwartz, Carlos Benaim, Henry G. Walter, Jr., Ronald S. Leight, Donald A. Withycombe, Braja D. Mookherjee, Robert W. Trenkle
  • Patent number: 4670463
    Abstract: Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of:(i) Nutmeg Oil;(ii) Mace Extract;(iii) Neroli Oil;(iv) Valerian Oil;(v) Myristicin;(vi) Isoelemicin; and(vii) Elemicin.Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfume article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.
    Type: Grant
    Filed: May 2, 1986
    Date of Patent: June 2, 1987
    Assignees: Yale University, International Flavors & Fragrances Inc.
    Inventors: Craig B. Warren, Marina A. Munteanu, Gary E. Schwartz, Carlos Benaim, Henry G. Walter, Jr., Ronald S. Leight, Donald A. Withycombe, Braja D. Mookherjee, Robert W. Trenkle
  • Patent number: 4670264
    Abstract: Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of:(i) Nutmeg Oil;(ii) Mace Extract;(iii) Neroli Oil;(iv) Valerian Oil;(v) Myristicin;(vi) Isoelemicin; and(vii) Elemicin.Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfumed article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.
    Type: Grant
    Filed: November 21, 1985
    Date of Patent: June 2, 1987
    Assignees: International Flavors & Fragrances Inc., Yale University
    Inventors: Craig B. Warren, Marina A. Munteanu, Gary E. Schwartz, Carlos Benaim, Henry G. Walter, Jr., Ronald S. Leight, Donald A. Withycombe, Braja D. Mookherjee, Robert W. Trenkle
  • Patent number: 4642240
    Abstract: Food acceptable sweetness modifying compounds comprising certain aromatic amino acids and foodstuff compositions containing the same.
    Type: Grant
    Filed: March 25, 1985
    Date of Patent: February 10, 1987
    Assignee: General Foods Corporation
    Inventors: Ronald E. Barnett, Ronald G. Yarger
  • Patent number: 4634548
    Abstract: The invention is concerned with novel bicyclic epoxides, a process for their manufacture and novel fragrance and flavor compositions containing the same.
    Type: Grant
    Filed: January 9, 1984
    Date of Patent: January 6, 1987
    Assignee: Givaudan Corporation
    Inventors: Daniel Helmlinger, Mario Pesaro
  • Patent number: 4590284
    Abstract: A compound of the general formula, ##STR1## wherein R.sub.1 and R.sub.2 independently are --H, --CH.sub.3, or --CH.sub.2 CH.sub.3 ; and R.sub.3 and R.sub.4 are independently alkyl or alkenyl of from 1 to 10 carbons, or aryl of from 6 to 10 carbons, or R.sub.4 =hydrogen.
    Type: Grant
    Filed: April 29, 1985
    Date of Patent: May 20, 1986
    Assignee: Hercules Incorporated
    Inventors: Brian Byrne, Louise M. L. Lawter
  • Patent number: 4571345
    Abstract: Compounds of the formula: ##STR1## wherein n is 0 or 1, R is lower alkyl (substituted or unsubstituted), R' is H or lower alkyl, and R" is a branched alkyl, alkyl-cycloalkyl, cycloalkyl, polycycloalkyl (poly=2 or more, fused or non-fused), phenyl or alkyl-substituted phenyl, and physiologically acceptable cationic and acid addition salts thereof, which compounds are potent sweeteners. These derivatives of gem-diaminoalkanes are many times sweeter than sugar and are free from undesirable flavor qualities. Furthermore, they possess an unanticipated high degree of solubility compared with known synthetic sweeteners. In addition, the compounds possess high stability so that they can be used in all types of beverages and in conventional food processing. Sweetening compositions and sweetened edible compositions of these compounds are also provided.
    Type: Grant
    Filed: June 13, 1983
    Date of Patent: February 18, 1986
    Assignee: Cumberland Packing Corp.
    Inventors: Michael S. Verlander, William D. Fuller, Murray Goodman
  • Patent number: 4570648
    Abstract: Novel esters, of the general formula ##STR1## wherein R represents C.sub.1-4 -alkyl or C.sub.2-4 -alkenyl and one of the three broken lines represents an additional bond,are disclosed. Also disclosed are novel odorant and/or flavouring compositions containing esters or formula I, a process and intermediates for the manufacture of the esters of formula I and the use of esters of formula I as odorant and/or flavouring substances.
    Type: Grant
    Filed: September 7, 1982
    Date of Patent: February 18, 1986
    Assignee: Givaudan Corporation
    Inventor: Hanspeter Schenk
  • Patent number: 4568470
    Abstract: Described for use in augmenting or enhancing the aroma or taste of consumable materials including perfume compositions, colognes and perfumed articles, foodstuffs, chewing gums, toothpastes and medicinal products are the cis and/or trans isomers of the macrocyclic lactone defined according to the structure: ##STR1## produced according to the process of first reacting the ester defined according to the structure: ##STR2## with the alkenol having the structure: ##STR3## in order to produce the di-unsaturated ester having the structure: ##STR4## and then causing the said diester to undergo an internal metathesis to form the compound having the structure: ##STR5##
    Type: Grant
    Filed: January 15, 1985
    Date of Patent: February 4, 1986
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Augustinus G. Van Loveren, Marie R. Hanna, Domenick Luccarelli, Jr., David R. Bowen, Manfred H. Vock, Wilhelmus J. Wiegers
  • Patent number: 4549029
    Abstract: Novel substituted tetrahydrofurans having a six-membered ring in the 4 position and methyl substituents in the 2 and 4 positions possess organoleptic properties described as fruity, citrus-like and reminiscent of grapefruit. These compounds are useful in fragrances and flavors.
    Type: Grant
    Filed: April 5, 1983
    Date of Patent: October 22, 1985
    Assignee: Givaudan Corporation
    Inventor: Alan R. Hochstetler
  • Patent number: 4537702
    Abstract: Perfume and flavoring compositions, perfumed articles and materials respectively flavored foods, drugs, toothpaste, and tobacco products containing 10-isopropyl-2.7-dimethyl-oxaspiro[4.5]deca-3.6-diene having formula ##STR1## as essential compound for imparting thereto an olfactive note of the cassis type as well as this compound per se.
    Type: Grant
    Filed: May 10, 1983
    Date of Patent: August 27, 1985
    Assignee: Naarden International N.V.
    Inventors: Antonius J. A. van der Weerdt, Harrie Renes
  • Patent number: 4522765
    Abstract: Described is di(7-octenyl) carbonate having the structure: ##STR1## and the use thereof as an intermediate in producing the compound having the structure: ##STR2## useful in perfumery.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: June 11, 1985
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Wilhelmus J. Wiegers, Augustinus G. Van Loveren, Marie R. Hanna, Domenick Luccarelli, Jr., David R. Bowen, Manfred H. Vock