Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

Abstract: A polyimide oligomer of formula (1a), (1b), a copolymer thereof, or a combination thereof wherein each G1 is independently the same or different, and is a cation group; each G2 is independently the same or different, and is an anion group; each D is independently the same or different, and is a single bond or C1-20 divalent hydrocarbon group; each V is independently the same or different, and is a tetravalent C4-40 hydrocarbon group; each R is independently the same or different, and is a C1-20 divalent hydrocarbon group; each n is independently the same or different, and is 1 to 1000, provided that the total of all values of n is greater than 4; and t is 2 to 1000.

Abstract: The present disclosure provides oral, chewable dosage forms that are suitable for delivery of one or more active ingredients to a consumer, particularly a human individual. The dosage forms can be configured as multicomponent compositions formed of a first component including a gummy composition, at least one further component including a composition that is different from the gummy composition, and an active ingredient. The gummy composition and the second composition can be co-deposited to form multicomponent dosage forms wherein a gummy shell at least partially surrounds a core that is solid or liquid at standard temperature.

Abstract: Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

Abstract: Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.

Abstract: Described herein are gummy compositions and products. In one aspect the gummy compositions include: (I) one or more gelating agents; (II) at least one fruit juice and/or fruit extract; and (III) 0.15-2 wt % caffeine. In a further aspect the invention provides a gummy composition comprising: (I) one or more gelating agents; (II) at least one fruit juice and/or fruit extract; (III) at least one vitamin; and (IV) 0.15-2 wt % caffeine. Also described herein are gummy products composed of the gummy compositions as well as methods of making and using the gummy compositions.

Abstract: The present invention relates to a novel bone graft and methods for producing the graft. The bone graft can be used for surgical, plastic and/or cosmetic bone replacement for a patient in need thereof. The bone graft is made of a scaffold or matrix of sheet material having a 3-dimensional pattern of a continuous network of voids and/or indentations for enhancing new bone growth.

Abstract: The present invention relates to a chewing gum comprising at least one polyethylene (PE) polymer in an amount from about 15% to about 99% by weight of the elastomeric polymer content of said chewing gum, at least one synthetic elastomer chosen from the group of Polyisobutylene (PIB), Butyl Rubber, Polyisoprene and Styrene Butadiene Rubber (SBR) in an amount from about 1% to about 85% by weight of the elastomeric polymer content of said chewing gum and wherein said at least one polyethylene polymer has a molecular weight (Mw) above 25,000 g/mol.

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a polymer matrix and one or more flavorants and/or active ingredients embedded in the polymer matrix. The polymer matrix can include a copolymer of ethylene and one or more vinyl monomers or zein. For example, the polymer can be ethylene-vinyl acetate copolymer and/or ethylene-vinyl alcohol copolymer. In some cases, the oral product can include tobacco and/or nicotine.

Abstract: A method and machine for coating confectionary product cores, whereby a mass of cores for coating is loaded into a chamber of a rotary drum and coated to form a shell on each core; forming the shell including at least one step of spraying the cores with sweet syrup, followed by at least one step of drying the syrup sprayed onto the cores; the drying step being performed by reducing the pressure in the chamber to less than ?0.2 bar, and heating the sprayed cores to a maximum of 35° C. using electromagnetic radiation, preferably microwaves.

Abstract: Low density chewing gums having a density of less than 0.60 g/cc comprise at least 50% polymer and less than 40% bulking agent and filler combined. The low density chewing gum may be produced by mixing the ingredients with supercritical fluid carbon dioxide and cooling the mixture. The mixture may optionally be cut into pieces and coated.

Abstract: A chewing gum contains a water-insoluble gum base portion containing a polyolefin thermoplastic elastomer; a water-soluble bulk portion; and at least one flavor component, which is cud-forming and chewable at mouth temperature.

Abstract: A photo-degradable chewing gum base composition including an elastomer; and a block copolymer of vinyl acetate and methylphenylsilane having a structure of formula (I)— wherein m and p are integers in the range of 1 to 500, and n is an integer in the range of 2 to 100, is disclosed. The block copolymer facilitates environmental degradation of improperly disposed chewing gum cuds. Also described is a method of preparing a photo-degradable chewing gum composition.

Abstract: Delayed release in chewing gum of an active ingredient, such as a sweetener or a food acid, is provided by encapsulating solid particles of the active ingredient in a polydiorganosiloxane. The resulting polydiorganosiloxane-encapsulated active ingredient includes a continuous phase with the polydiorganosiloxane and a disperse phase with the solid particles of the active ingredient. When incorporated into a chewing gum, the polydiorganosiloxane-encapsulated active ingredient provides a more delayed release than conventional poly(vinyl acetate)-encapsulated active ingredients.

Abstract: A gum base comprising: a) a hydrophilic precursor component comprising hydrolysable units; and b) a copolymer of a hydrophilic monomer with a second monomer selected from vinyl acetate, isobutylene, isoprene, butyl rubber or styrene butadiene. This chewing gum base contributes to the ability of the chewing gum compositions and chewing gum products to degrade over time after chewing by imparting the chewing gum with increased hydrophilic properties.

Abstract: Architecture that provides model-based systems management in virtualized and non-virtualized environments. A security component provides security models which define security requirements for services. A management component applies one or more of the security models during the lifecycle of virtual machines and services. The lifecycle can include initial deployment, expansion, moving servers, monitoring, and reporting. The architecture creates a formal description model of how a virtual machine or a service (composition of multiple virtual machines) is secured. The security requirements information can also be fed back to the general management system which uses this information in its own activities such as to guide the placement of workloads on servers can be security related.

Abstract: A chewing gum comprising at least one active pharmaceutical ingredient (API) with a core onto which is applied at least one inner polymer film coating and thereafter onto which is applied at least one outer hard coating. A preferred API is nicotine. Flavoring agents may be incorporated in the core, in the at least one inner polymer film coating and/or in the at least one outer hard coating. The gums formed exhibit a long lasting effect of flavoring agent(s) and result in the domination of flavoring agents in the coating(s) over flavoring agent(s) in the core, thereby (a) avoiding problems of chemical or pharmaceutical incompatibility between an API in the core and flavoring agent(s) in the coating(s) and (b) achieving an increased control of the release of the API and of non-active excipients.

Abstract: In some embodiments there is a composition including a thermally stabilized active composition and a high molecular weight polymer. The thermally stabilized active composition is resistance to degradation at higher temperatures such as those used for conducting extrusion with high molecular weight polyvinyl acetate.

Abstract: A chewable confectionery dental composition delivering to the mouth a unit dose of a plaque reducing enzyme the composition comprising an enzyme and a non-cariogenic sweetener, the enzyme being incorporated in the composition at a temperature less than about 80° C.

Abstract: The present invention relates to a chewing gum base formulation comprising a biocompatible particulate polymer having an average particle size of from about 200 ?m to about 2000 ?m wherein the polymer fibrillates when subjected to a shear stress such as that encountered during chewing.

Abstract: A compressed chewing gum tablet including a chewing gum center, the gum center including a compression of gum base granules and chewing gum additives. The chewing gum additives include sweeteners and flavors. At least a first part of the gum base granules have granules of flavor incorporated gum base and at least a second part of the gum base granules have granules of conventional gum base.

Abstract: The invention provides a chewing gum base containing a homogeneous composition in solid form comprising a) from 50 to 90% by weight of polyvinyl acetate and b) from 10 to 50% by weight of vinyl acetate-vinyl laurate copolymer, the weight percentage based on the total weight of the composition.

Abstract: A gum base which, when formulated into a chewing gum, provides a gum cud removable from environmental surfaces, contains 40-95 wt. % polyethylene having a weight average molecular weight of 2000 to 23000 daltons.

Abstract: A chewing gum comprising at least one active pharmaceutical ingredient (API) with a core onto which is applied at least one inner polymer film coating and thereafter onto which is applied at least one outer hard coating. A preferred API is nicotine. Flavoring agents may be incorporated in the core, in the at least one inner polymer film coating and/or in the at least one outer hard coating. The gums formed exhibit a long lasting effect of flavoring agent(s) and result in the domination of flavoring agents in the coating(s) over flavoring agent(s) in the core, thereby (a) avoiding problems of chemical or pharmaceutical incompatibility between an API in the core and flavoring agent(s) in the coating(s) and (b) achieving an increased control of the release of the API and of non-active excipients.

Abstract: A chewing gum, when chewed, produces a cud having improved removability from environmental surfaces by virtue of its linear viscoelastic shear rheology. The cud has a specified temperature dependent storage modulus differential (? log G?/?T) at 25° C. and 60° C. Specifically, the cud has a temperature dependent storage modulus differential less than 0.050.

Abstract: The invention relates to chewing gum comprising at least two different biodegradable polymers. According to the invention, a chewing gum comprising at least two different biodegradable polymers exhibits an improved texture prior to any adding of for example softeners. It has been realized that the desired chewing gum texture properties, contrary to every expectation and any prior art disclosures, may be actually be obtained when combining biodegradable chewing gum polymers, for example in the gum base or in the final gum.

Abstract: The present invention provides gum base compositions and chewing gum compositions having non stick or reduced-stick properties and/or increased degradability. Methods of preparing the gum base and chewing gum compositions, as well as methods of use, are provided.

Abstract: The present invention provides gum base compositions and chewing gum compositions having non stick or reduced-stick properties and/or increased degradability. Methods of preparing the gum base and chewing gum compositions, as well as methods of use, are provided.

Abstract: The present invention provides gum base compositions and chewing gum compositions having non stick or reduced-stick properties and/or increased degradability. The compositions include a terpolymer of methylvinyl ether, maleic anhydride and maleic acid, which provide increased degradability. Methods of preparing the gum base and chewing gum compositions, as well as methods of use, are provided.

Abstract: The invention provides a chewing gum base containing a homogeneous composition in solid form comprising a) from 50 to 90% by weight of polyvinyl acetate and b) from 10 to 50% by weight of vinyl acetate-vinyl laurate copolymer, the weight percentage based on the total weight of the composition.

Abstract: The present invention provides gum base compositions and chewing gum compositions having non stick or reduced-stick properties and/or increased degradability. Methods of preparing the gum base and chewing gum compositions, as well as methods of use, are provided.

Abstract: The present invention relates to a chewing gum base for use in chewing gum compositions wherein the chewing gum base contributes to the ability of the chewing gum compositions to degrade over time after chewing, and also the chewing gum compositions containing the chewing gum base. The chewing gum base comprises a hydrophilic precursor component having a particular molecular weight and/or a particular average particle size.

Abstract: Lactobacillus delbrueckii having antifungal activity is provided as novel lactic acid bacteria having antifungal activity. The Lactobacillus delbrueckii is Lactobacillus delbrueckii ANTI MUFFA FERM BP-10663 (FERM P-19705). The Lactobacillus delbrueckii has antifungal activity against mold of genus Penicillium and is excellent in probiotic activity even when used solo.

Abstract: A chewing gum includes a polyester having as polyester-forming components in condensed form: (a) a dicarboxylic acid, (b) a diol and (c) a compound having at least three groups capable of ester formation in an amount of from 0.1 to 10.0% by weight, based on the total weight of components (a), (b) and (c). The polyester includes components (a) and (b) in an amount of at least 90% by weight, based on the total weight of the polyester. The chewing gum includes the polyester in an amount of at least 5% by weight of the chewing gum. The chewing gum further includes a sweetening agent and/or a flavoring agent in an amount of 10 to 95% by weight of the chewing gum. The molar ratio between aromatic acids and aliphatic acids of the dicarboxylic acid is between 0 and 1:4.2.

Abstract: In some embodiments there is a composition including a thermally stabilized active composition and a high molecular weight polymer. The thermally stabilized active composition is resistance to degradation at higher temperatures such as those used for conducting extrusion with high molecular weight polyvinyl aceate.

Abstract: A chewing gum contains a water-insoluble gum base portion containing a solution-polymerized styrene-butadiene random copolymer elastomer which is cud-forming and chewable at mouth temperature; a water-soluble bulk portion; and at least one flavor component.

Abstract: The invention relates to chewing gum comprising at least two different biodegradable polymers. According to the invention, a chewing gum comprising at least two different biodegradable polymers exhibits an improved texture prior to any adding of for example softeners. It has been realized that the desired chewing gum texture properties, contrary to every expectation and any prior art disclosures, may actually be obtained when combining biodegradable chewing gum polymers, for example in the gum base or in the final gum.

Abstract: The invention provide a gum base composition which has an excellent chewing texture and is disintegratable and biodegradable comprising biodegradable ingredients, including a lactic acid polymer comprising a poly-L-lactic acid polymer and/or other lactic acid polymers having a glass transition temperature higher than 50° C. in an amount of from 5% by weight to 60% by weight, and an emulsifying plasticizer in an amount of from 1% by weight to 20% by weight. The weight average molecular weight of the lactic acid polymer to be used is preferably 50,000 to 200,000.

Abstract: An amphiphilic polymeric material which has a straight or branched chain polymer backbone and a multiplicity of side chains attached to the backbone, wherein the backbone is a copolymer of at least one ethylenically-unsaturated aliphatic hydrocarbon monomer and maleic anhydride, or is a terpolymer of maleic anhydride, ethylene, and a further ethylenically unsaturated monomer. A method of synthesising said polymeric material is also provided, together with chewing gum bases, compositions and emulsions comprising amphiphilic polymeric materials.

Abstract: Chewing gum base including i. 1 to 99% by weight of a polymeric material which has a straight or branched chain carbon-carbon backbone and a multiplicity of side chains, and is substantially insoluble in water; ii. from 0-6% by weight wax; iii. up to 99% by weight of an elastomeric material different to the polymeric material; and iv. 0 to 20% by weight of an elastomer plasticiser; in which the total amount of polymeric material and elastomeric material is at least 10% by weight of the chewing gum base. A chewing gum composition including this chewing gum base, and methods of manufacture, are also provided.

Abstract: The present invention provides a chewing gum composition comprising a chewing gum base, a biologically active ingredient, a polymeric material and one or more sweetening and flavouring agents, wherein the polymeric material is amphiphilic, has a straight or branched chain carbon-carbon backbone and a multiplicity of side chains attached to the backbone. A method of making the chewing gum composition is also provided.

Abstract: The invention relates to a confectionery product comprising a polymer system, flavor and sweetener, at least about 70% by weight of said polymer system comprising polyvinyl acetate (PVAc) and less than 10% by weight of said polymer system comprises polymer having a molecular weight (Mw) of greater than about 50000 g/mol.

Abstract: The present invention provides a degradable chewing gum base, degradable chewing gum, and methods of making a degradable chewing gum base and degradable chewing gum. The degradable chewing gum base includes at least one polymer or oligomer with at least two ionic groups. The polymers and oligomers possess the chewing characteristics and texture traditionally desired in a chewing gum while simultaneously providing materials which, when exposed to environmental conditions, break down to non-toxic molecules readily assimilated by nature.

Abstract: The present invention relates to optimization of flavored polymeric compositions and methods of producing optimized flavored polymeric compositions. More specifically, the invention relates to flavored polymeric compositions comprising “flavor enhancing agents” alone or in combination with other flavorants as well as polymeric articles made from the same, wherein articles made from such polymeric compositions are not intended to be consumed, significantly destructed, masticated or fully or partially dissolved to release flavor.

Abstract: A molten plastic extruded from extruding means 10 is formed into a strand 50 by a die 40, passed through an inner side of a cylindrical guide 60 erected vertically, thereafter, the strand 50 is successively cut uniformly to a constant length by a cutter 90 to form a pellet. A refrigerant for air cooling is circulated at a surrounding of the strand 50 passing through the inner side of the cylindrical guide 60 by cooling means 100 of the strand without being leaked to outside air.

Abstract: The present invention relates to a chewing gum comprising at least one polyethylene (PE) polymer in an amount from about 15% to about 99% by weight of the elastomeric polymer content of said chewing gum, at least one synthetic elastomer chosen from the group of Polyisobutylene (PIB), Butyl Rubber, Polyisoprene and Styrene Butadiene Rubber (SBR) in an amount from about 1% to about 85% by weight of the elastomeric polymer content of said chewing gum and wherein said at least one polyethylene polymer has a molecular weight (Mw) above 25,000 g/mol.

Abstract: Polyvinyl acetate polymers produced by mass polymerization or suspension polymerization are stabilized against blocking by addition of minor amounts of a silicon oxide compound during the pelletization process of mass polymerized polymers and prior to or during fluidized bed drying in the case of suspension polymerized polymers. The free flowing polymers are suitable for use as chewing gum bases, and for other uses.

Abstract: The invention relates to new derivatives of 2-methyl-3-furanthiol which are useful as flavoring ingredients to confer meaty, juicy taste to a large variety of edible consumer products, chewing gums and oral care products, without imparting thereto undesirable off-notes typical of prior known furanthiol derivatives.

Abstract: The invention relates to chewing gum comprising at least one biodegradable polyester copolymer obtained by the polymerization of two or more cyclic esters by ring-opening, said at least one biodegradable polyester copolymer having a molecular weight of less than 150000 g/mol and said chewing gum further comprising chewing gum ingredients. According to the invention, an improved release of chewing gum ingredients has been obtained when a texture acceptable biodegradable polyester copolymer are applied as a chewing gum polymer.

Abstract: The invention relates to a confectionery product comprising at least one transparent module (TM) and at least one form stable support module (SM) and where said transparent module comprises gum base. By applying a transparent gum base comprising module, also referred throughout the application as a transparent module (TM), a whole new experience is present for the consumer. In some embodiments the confectionery may act and feel like an ordinary confectionery from the moment it is placed in the mouth but at the same time it gives the consumer an advantageous visual impression prior to placing it in the mouth.