Abstract: An enteral nutritional product containing either bovine .kappa.-casein or human .kappa.-casein at a concentration greater than that found in human or bovine milk and sufficient to inhibit infection of mammalian cells by human rotavirus.

Abstract: The salty taste of a food or beverage is enhanced by adding to the food or beverage a dehydrated composition containing from about 15% to about 65% by weight of an ammonium salt and from about 35% to about 85% by weight of a proteolyzed protein. The dehydrated composition contains from about 0.2% to about 3% free lysine and from about 0.2% to about 3% free arginine.

Abstract: A granular particulate composition, which may be employed to coat an exterior surface of a food, particularly meat, to provide for fluid retention, is prepared by combining individual particles of aggregated solids of intracellular starch, undenatured milk protein and uncoagulated egg albumen, the individual particles being formed by at least one of the milk protein, egg albumen and intracellular starch solids. The granular composition may be prepared by drying an aqueous mixture of egg albumen, milk protein, and intracellular starch under conditions of temperature which substantially avoid coagulation of the albumen, denaturation of the protein and gelatinization of the starch to obtain a mixture dried suitably for being formed into granules and by forming the dried mixture into granules.

Abstract: A liquid enteral nutritional product has been formulated which has utility, for example, for persons with cancer who are not currently undergoing radiation therapy and/or chemotherapy. The nutritional product is characterized by a fatty acid profile wherein, by weight: (a) the ratio of the sum of the n-3 to n-6 fatty acids is in the range of 1.37 to 1.70; (b) Eicosapentaenoic Acid (23:6n-3) is about 2.7-3.0% of total fatty acids.; and (c) Docosahexaenoic Acid (22:6n-3) is about 1.3-1.4% of total fatty acids. Preferably the nutritional product also contains intact protein, .beta.-carotene, carnitine and taurine.

Abstract: A novel and low allergenic nutrient composition is discribed. The composition contains Kappa-caseinglycomacropeptide and, optionally, one or more other amino acid sources selected from amino acids, peptides, or proteins, as nitrogen sources. The nutrient composition provides a favorable taste, no allergenicity, a high nutritive value, good absorptivity and digestibility, and a superior antiinfective effect. It can be served as formulas, enteral feeding nutrients, tube feeding nutrients, or nutritious supplements.

Abstract: Production of human procollagen or collagen in cells which ordinarily do not produce these molecules is effected by constructing expression systems compatible with mammary glands of non-human mammals. For example, expression systems can be microinjected into fertilized oocytes and reimplanted in foster mothers and carried to term in order to obtain transgenic non-human mammals capable of producing milk containing recombinant human procollagen or collagen. Human procollagen or collagen produced in this manner can be made of a single collagen type uncontaminated by other human or non-human collagens.

Abstract: There is disclosed an antimicrobial agent comprising one or more of antimicrobial peptides derived from lactoferrins, and one or more of specific compounds and/or at least an antibiotic, and a method for treating matters with said antimicrobial agent. The antimicrobial agent has a potent antimicrobial activity against wide variety of microorganisms, thus it is useful not only as a medication, but also useful for making antimicrobial treatment of matters such as foods, non-medical products, and the like with safety and great efficiency.

Abstract: There is disclosed a stable animal feed supplement suspension which is prepared by forming a stable liquid gel in concentrated food industry by-products such as by-products of the dairy industry, such as whey permeates, delactosed whey, and by-products of the fermentation industry, such as whey and corn sweet water. These by-products have not been used with any significant success in animal feed supplements, despite their low cost and disposal problems. A major disadvantage is their limited solubility, and the resultant instability of concentrates of the by-products. The invention comprises the treatment of the protein-rich by-products with a mild enzymatic treatment which stabilizes the by-products against protein gelation, and the thermal, and/or enzymatic treatment of the lactose-rich by-products to avoid separation of the lactose from concentrates.

Abstract: There is disclosed a solid animal feed supplement which is prepared in concentrated food industry by-products such as by-products of the dairy industry, such as whey permeates, delactosed whey, and by-products of the fermentation industry, such as whey and corn sweet water. The invention comprises the treatment of the protein-rich by-products with a mild enzymatic treatment which stabilizes the by-products against protein gelation, and the thermal, and/or enzymatic treatment of the lactose-rich by-products to avoid separation of the lactose from concentrates. The by-products can then be concentrated to high solids content, in excess of 50 weight percent, and the resultant concentrates can be treated with gelation agents, preferably phosphoric acid and lime to solidify the by-product. Feed nutrients such as fats, urea, sodium bicarbonate, calcium carbonate, calcium sulfate, etc., or drugs such as monisan, can be added before solidification forming useful solid animal feed supplements.

Abstract: A method and composition for producing an edible casing from an aqueous gelatin plasticizer composition which is given specific through-put parameters by means of a elongated rotating extruder which terminates in a die extruder for forming a film. The aqueous gelatin composition may also contain chitosan and/or hydroxypropylcellulose. Optionally, cross-linking agents, coloring agents, flavoring agents, preservatives and/or antioxidants may be included.

Abstract: Biodegradation additive characterized in that it consists of a mixture of (i) at least one assimilable nitrogen source composed of at least one unsubstituted or substituted amino acid; (ii) at least one phosphorus source, the ratio of nitrogen to phosphorus ranging from 2 to 100, said additive being subjected to a treatment to make it oleophilic. The invention also concerns an additive in accordance with any of the foregoing claims for the biodegradation of hydrocarbons.

Abstract: A protein hydrolyzate is produced from mucosa tissue of pigs, cattle or sheep by providing an aqueous mixture of the tissue, hydrolyzing the tissue with a proteolytic enzyme at a salt concentration of less than 0.1 molar to produce a digest solution containing a protein hydrolyzate and polyanions including heparin, adsorbing the polyanions on an anion exchange resin, recovering the anion exchange resin containing adsorbed polyanions to provide a digest solution containing less than 2.9 u/ml residual heparin and recovering the protein hydrolyzate from the digest solution by screening or dehydration. The protein hydrolyzate contains less than 15% ash, between 9.5 and 11.5% total Kjeldahl nitrogen and between 5.0 and 7.0% alpha amino nitrogen. The protein hydrolyzate may be used in nutritional formulations such as to promote weight gain in newly weaned livestock and in medical formulations such as peritoneal dialysis fluids and formulations for use in enteral and parenteral mutrition.

Abstract: Processes for stabilizing protein in acid pH media are provided as well as the compositions produced thereby. Acidified protein compositions exhibiting protein stability for extended periods of time are also provided. The processes of the present invention promote chemical reaction between protein and galactomannan to achieve protein stability in acid pH media.

Abstract: The RIAL biopreparation contains free and fixed amino acids, lipids, macronutrients and microelements, compounds of non-metals, carbohydrates and moisture in the following proportions, 30-40, 30-55, 0.01-2, 2-6, 0.5-1.5, 8-12, 0.001-0.1, 4-10 wt.-%, respectively. The method for feeding various groups of animals, poultry and bees involves introducing the RIAL biopreparation into their basic ration. The dose of the preparation used in animal breeding is 10-100 mg/kg of body weight. In poultry farming, the dose is 330-625 g/t of feed. In apiculture, the RIAL preparation is introduced into sugar syrup in a dose of 50-150 mg/l of syrup.

Abstract: A process for isolating the metalloprotein lactoferrin and the enzyme lactoperoxidase from milk and milk products on an industrial scale is disclosed. The process includes the steps of adsorbing these proteins to a cation exchanger by passing milk or the milk derivatives over the cation exchanger at a high superficial velocity (more than 500 cm per hour) and at a high liquid load (100-600 bed volumes per hour); eluting these proteins, separately or simultaneously, by elution with one or more salt solutions, so as to form one or more eluates; and optionally followed by drying of the eluates.

Abstract: Disclosed is a milk protein partial hydrolysate prepared by enzymatic hydrolysis and infant formula prepared therefrom. The hydrolysate has reduced antigenicity and is prepared from a mixture of whey protein and casein wherein the degree of hydrolysis is between 4 and 10%.

Abstract: This invention pertains to protein compositions having reduced-hygroscopic properties which comprise a homogeneous premixture of (a) a hygroscopic protein and (b) an effective amount of a protein complexing agent to reduce the hygroscopic properties of the protein. The reduced-hygroscopic protein compositions may be used directly or may be incorporated in effective amounts into edible carriers to provide a wide variety of edible compositions. This invention also pertains to methods for preparing these improved protein compositions and the edible compositions in which they may be employed.

Abstract: A pet food premix product is provided, comprising a mixture of about 40 to 70 wt % of non-rendered meat and the balance at least one farinaceous and/or plant proteinaceous carrier substrate. One or more meats may be employed. A process is provided by which meat can be efficiently dehydrated and starch can be partially or completely gelatinized, then incorporated into an extruded dry or moist food at levels from 5 to 50% of a total formulation ration. The premix, when incorporated into an extruded pet food product, will increase its operational performance while delivering nutrients and palatability to the pet food product. In addition, a dried bakery product, is provided, which is useful as the farinaceous carrier substrate in the fabrication of the pet food premix product. The dried bakery product provides a naturally low pH pet food product having a pH in the range of about 5.7 to 6.4 and also unexpectedly provides an energy reduction in extrusion of pet food containing this ingredient.

Abstract: A low buffer nutritional composition which is useful to reduce the incidence of colonization of pathogenic bacteria.

Abstract: A grillable/broilable food product is disclosed. The product is based upon meat, fish or other seafood, poultry or vegetables, and is coated with an edible artificial skin forming composition which reduces sticking or charring of the food product to or on a hot surface. The composition utilizes a blend of an alkyl cellulose ether and a protein, e.g. a plasma protein, and optionally a gum or browning agent, and a flavorant.

Abstract: A grillable/broilable food product is disclosed. The product is based upon meat, fish or other seafood, poultry or vegetables, and is coated with an edible artificial skin forming composition which reduces sticking or charring of the food product to or on a hot surface.The composition utilizes a blend of an alkyl cellulose ether and a protein, e.g. a plasma protein, and optionally a gum or browning agent, and a flavorant.

Abstract: A plastein material is made by reversing the normal hydrolytic activity of a serine protease. The protease produces a plastein material by acting on a proteinaceous substrate. The substrate is preferably whey, casein or soy protein.

Abstract: The invention provides biodegradable, thermoplastic compositions made of the reaction product of soybean protein and a carbohydrate filler, a reducing agent, a plasticizer, water, and optional additives as desired. The composition has a high degree of flowability for processing by extrusion and injection molding into solid articles that are biodegradable with a high degree of tensile strength and water resistance.

Abstract: A liquid enteral nutritional product contains a protein system of, by weight, about 50-90% of a soy protein hydrolysate having a degree of hydrolysis in the range of 14 to 17% and not more than 50% of one or more intact protein sources. The nutritional product may also contain an emulsifier, Iota carrageenan and Kappa carrageenan.

Abstract: A non-heating type food binder which contains one or more natural proteins containing an amine acid unit with an --OH group or an --NH2 group and one or more powdery products selected from the group consisting of a hydroxide of an alkaline earth metal, an oxide of an alkaline earth metal, powdery calcined or burned eggshell, powdery calcined or burned shell, powdery calcined or burned bones and the mixtures thereof. The binding is achieved through the formation of bonds forming bridge linkage between a bivalent ion with the groups of the protein amino acid units of the protein of the binder and of the food. The food binder provides good binding properties without introducing undesirable taste or flavor and is easy to use.

Abstract: A method of providing enteral nutritional support to a person who is currently undergoing chemotherapy and/or radiation therapy involves including in the person's diet an enteral nutritional product having a protein system which includes a soy protein hydrolysate. The nutritional product is very low in folic acid, contains .beta.-carotene, and has a ratio of n-6 to n-3 fatty acids that is in the range of about 1.3:1 to 2.5:1.

Abstract: A process for producing an .alpha.-lactalbumin-enriched fraction from whey is disclosed. The process involves heating pH-adjusted whey to a temperature sufficient to cause aggregation of .beta.-lactoglobulin molecules, and fractioning the whey using ultrafiltration or microfiltration, the .alpha.-lactalbumin-enriched fraction obtained by the process is useful for making breast milk substitutes and other nutritional compositions.

Abstract: The present invention is a process for flash flow processing a feedstock including a protein, a maltodextrin or a polydextrose and fructose and the product resulting therefrom.

Abstract: A partially denatured whey protein product with a protein content of 65-95% by weight relative to the dry matter, a protein denaturization level of 55-80%, and a mean particle size in the range from 30 to 60 .mu.m, in particular 40-50 .mu.m. The product is suitable for use in foods as an additive with an emulsifying action and good organoleptic properties, particularly in cold-prepared emulsions.

Abstract: A modified cultured yeast product for human and animal consumption is produced by combining yeast cream and yeast centrate to produce a cream/centrate mixture, autolyzing the mixture, inactivating by heating the mixture and optionally drying. After autolysis, hydrolysis may be carried out by the use of acids, alkalis or enzymes. The yeast cream and yeast centrate are preferably produced by culturing Kluveromyces marxianus or Candida intermedia in a whey permeate and separating yeast cream and yeast centrate from the cultured whey permeate. The cream and centrate are combined such that the ratio of total solids of cream to total solids of centrate is between about 0.3 and 1.6 and preferably about 1:1.

Abstract: Enteral nutritional support for a person infected with human immunodeficiency virus is provided by including in the diet a nutritional product which contains a soy protein hydrolysate having a degree of hydrolysis in the range of about 14 to 17 and a molecular weight partition, as determined by size exclusion chromatography, wherein 30-60% of the particles have a molecular weight in the range of 1500-5000 Daltons. The nutritional product also contains a source of intact protein. The nutritional product has a ratio, by weight, of n-6 to n-3 fatty acids of about 1.3:1 to 2.5:1. The nutritional product also contains a source of dietary fiber.

Abstract: A proteinaceous product comprises a stable, substantially clear, thermally irreversible gel formed by the reaction product of protein and reducing sugar, preferably containing from 2 to 25% gel-forming protein by weight. Particles or pieces of edible material may be embedded in the gel, or the gel may be divided into pieces and incorporated as an ingredient in a food product, and the product can be rendered commercially sterile while remaining substantially clear. Such products can be produced by a process which comprises reacting an aqueous dispersion of a protein or proteinaceous material with a reducing sugar or source thereof in the presence of a denaturing agent (e.g. a chaotropic agent), and/or denaturing conditions (e.g. alkaline pH).

Abstract: The invention concerns ready-to-use glazing agents with the composition:5-25 wt. % of liquid vegetable oil;5-15 wt. % of casein or its salts;0.005-10 wt. % of emulsifier;0.1-8.0 wt. % of a compound giving a browning upon heating, preferably by a Maillard-type of reaction andbalance: water.The composition is sterilizable and has a shelf-life after sterilization of more than 3 months.

Abstract: The present invention relates to low-fat or fat-free substances which can be used as replacements for fat (i.e., fat substitutes or fat extenders), both per se as well as in the preparation of food products. Specifically, the present invention relates to gel systems which have been size reduced to mimic fat. The gel systems are based on gels which are produced from undenatured whole milk protein and carrageenan. These gels are broken and sized by shear to produce particles which are under two microns in size. Particles of this size are described as having a "fatty mouth feel" which means that the particles have a fat-like organoleptic character. The gel systems of the present invention may be used to replace some or all of the fats which are normally present in a variety of food products. The present invention also relates to processes for producing the fat substitutes and to food products containing the fat substitutes.

Abstract: A feed for swine containing a casein digestion product of which a principal component is casein phosphopeptide, and a method of breeding a swine which comprises feeding a feed for swine containing 0.01 to 1 part by weight of a casein digestion product of which a principal component is casein phosphopeptide per 100 parts by weight of usual feed for swine. By feeding the feed for swine of the invention, the absorption of minerals, such as calcium and iron is promoted in pregnant sows, resulting in the improvement in the blood properties and milk quality. Piglets are slao improved in the blood properties and ossification degree by feeding the feed for swine of the invention.

Abstract: Non-yeast protein is mixed with yeast, and enzymatic hydrolysis is carried out with yeast autolytic enzymes and optionally added exogenous enzymes to produce a yeast extract containing hydrolyzed non-yeast protein. More specifically, a mixture of yeast cells and 5 to 50% of cereal and/or animal non-yeast protein source is maintained at 40.degree. to 50.degree. C. for 5 to 15 hours and then at 55.degree. to 65.degree. C. for 1 to 5 hours to allow enzymatic hydrolysis to produce a water-soluble fraction. The water-soluble fraction is separated and concentrated. The non-yeast protein source may be one or more of maize gluten, corn gluten, wheat gluten, soya bean meal, whey solids, dried red blood, oat bran and wheat bran. By appropriate selection of the non-yeast protein, a yeast extract with specific flavor can be produced for use as a taste additive in the food industry.

Abstract: Collagen beads prepared by adding spherical droplets of an aqueous liquid of collagen to an aqueous solution of tannin. The collagen beads show a uniform grain size and have either a two-layered structure consisting of an aqueous liquid sustained inside a solidified outer surface or a completely solidified form.

Abstract: Processes for stabilizing protein in acid pH media are provided as well as the compositions produced thereby. Acidified protein compositions exhibiting protein stability for extended periods of time are also provided. The processes of the present invention promote chemical reaction between protein and galactomannan to achieve protein stability in acid pH media.

Abstract: A composition intended for use in dietetics, reanimation and therapeutics is provided. The composition includes lactoserum minipeptides, casein minipeptides, and casein minipeptides without phosphopeptides. The selected minipeptides are present in an amount sufficient to assure a proper balance between a level of sulfur-containing amino acids and a level of phosphorus bound to proteins.

Abstract: Disclosed is a milk protein partial hydrolysate prepared by enzymatic hydrolysis and infant formula prepared therefrom. The hydrolysate has reduced antigenicity and is prepared from a mixture of whey protein and casein wherein the degree of hydrolysis is between 4 and 10%.

Abstract: The invention provides a process for improving HCl-hydrolysed protein by subjecting an aqueous solution thereof to hydrolysis (of monochloropropanediols and dichloropropanols) at a pH between 5.5 and 8.0 at a temperature between 20.degree. and 180.degree. C. for a period between 10 days to 15 minutes. Preferably the pH lies between 6.5 and 8.0, the temperature lies between 80.degree. and 120.degree. C. and the aqueous mixture contains 10 to 85% of solid material Also it is preferred to carry out the hydrolysis is carried out in the presence of 0.1 to 10% (w.w.) of added phosphate, C2-C6 carboxylic acid or salt thereof.

Abstract: The invention pertains to a process for preparing a phenylalanine-free dietetic product comprising L-amino acids, and optionally comprising carbohydrates, minerals, trace elements and/or vitamins, for persons afflicted with phenylketonuria particularly adults, juveniles and pregnant women. The process comprises preparing a wet batch by dispersing in water the L-amino acids, some or all of the optional components, and at least one fatty material as an emulsifier, after which the wet batch is spray-dried. The spray-dried wet batch is then mixed with additional vitamins and/or carbohydrates and at least one fatty material as a separation agent to produce a mass. The mass thus produced is processed into cores for dragees or tablets, and the dragee or tablet cores are provided with coatings or dragee covers. The dietetic product is used as a nutrition supplement.

Abstract: Lactoferrin hydrolyzates, having a decomposition rate between 6%-20% as measured by formol titration, for use as an antibacterial agent, and which have remarkably more potent activity than unhydrolyzed lactoferrin; and lactoferrin hydrolyzates, having a decomposition rate between 4-50% as measured by formol titration, for use as a tyrosinase inhibition agent, are obtainable by conventional methods for hydrolysis with acids or enzymes, and are stable to heating.

Abstract: In accordance with the present invention, there is provided a method for simultaneously producing: natural muscle protein having very low fat and cholesterol content; stabilized myoglobin pigment; broth with superior gelling, emulsifying and film forming properties; high quality animal fat; and bone meal with consistent calcium and phosphate content. The above products are produced from comminuted animal carcass by-products which are divided into a solid-phase fraction and a solution-phase fraction. The broth, fat and bone meal products are prepared from the solid-phase fraction, and the protein and pigment products are prepared from the solution-phase fraction.

Abstract: The articles are made by mixing an animal protein product of meat, from which the fat has been removed by extraction with a gas in liquid or overcritical state, and starchy grain or vegetable material, plus other additives if necessary, into a mixture of semifluid to pasty consistency. The mixture obtained is extruded, with the addition of water, to form a substantially plastically workable material which is put into the desired shape by means of injection molding. The method may be used for making articles such as disposable tableware and cutlery for households and the catering trade, packaging, or casings.

Abstract: A formulation and process is provided for the production of firm, irreversible protein-containing elastic gels which can be used in the production of food analogs including kamaboko or seafood analogs. In this process a mixture of calcium caseinate, sodium hexametaphosphate, and either a carrageenan or a combination of lactalbumin and egg albumin, are blended in an aqueous mixture to form a homogeneous blend. The blend, upon heating to form a uniformly viscous solution, is subsequently cooled to form an edible gel.

Abstract: An improved method of preserving the flavor in a food product, such as a low calorie food bar, is characterized by stabilizing the flavoring by plating the flavoring on synthetic amorphous silica. An improved flavoring system for a food product contains aspertame and/or proteinaceous material in combination with a flavoring plated on synthetic amorphous silica.

Abstract: Method for instantaneous gelling or coagulation, in the absence of coagulant agent, at a pH higher than its isoelectric pH, of a coagulable protein at said isoelectric pH, characterized in that an aqueous solution is used as starting product, wherein the aqueous solution is in a nondenatured status, and contains at least one such coagulable protein, the alkaline ion content of said solution is adjusted to a predetermined value, and is brought to a concentration at least equal to 1.5% at a temperature selected as desired between 20.degree. and 100.degree. C. The predetermined value is such that the protein coagulates instantaneously, at the above concentration and pH, and temperature; to obtain the coagulum. Application of such coagulums to obtain semi-solid or solid food products containing animal proteins such as milk proteins or vegetable proteins such as soya proteins.

Abstract: An enzymatic hydrolysate having a high di- and tripeptide content is prepared by subjecting to enzymatic proteolysis a protein mixture preliminarily prepared by means of a thermal treatment. The hydrolysate having a high di- and tripeptide content is extracted by liquid-solid separation, followed by ultrafiltration. The hydrolysate is then subjected to a sterilization and drying operation.

Abstract: Non-phosphorylated peptides and phosphopeptides useful as alimentary products or medicaments are produced by proteolytic enzyme hydrolysis of a casein-based material. Membrane ultrafiltration is used to separate phosphopeptides which are retained by the membrane in a retentate from the non-phosphorylated peptides which pass through the membrane in an ultrafiltrate. The phosphopeptides in the retentate are disaggregated and are subjected to further membrane ultrafiltration where the phosphopeptides pass through the membrane and are separated from the enzyme. The non-phosphorylated peptides have nutritive value and can be used to form compositions for providing nutrition. The phosphopeptides form salts, which have dietetic uses, with macroelements such as calcium and/or magnesium and/or oligoelements such as iron and zinc.