Abstract: The invention described here provides ready-to-use (RTU) pharmaceutical compositions in single unit dose packaging, such compositions including ascorbic acid compound(s), such as sodium ascorbate, and one or more pharmaceutically acceptable excipients (e.g., a carrier and optionally other agents, such as a tonicity agent, a chelator, or both). The compositions provided by the invention are stable when stored at 20° C. to 25° C.±2° C. for at least about 3 months. Compositions provided by the invention comprise an osmolality of between about 270 mOsm/kg to about 340 mOsm/kg and do not require dilution or further manipulation prior to use. In certain aspects, the invention comprises methods of using such compositions in the treatment of diseases, conditions, or symptoms related to vitamin C deficiency, such as, in specific embodiments, scurvy.

Abstract: A process for concentrating a maple sap or sweet vegetal water solution is provided. The process comprises collecting the solution in a tank at temperature T1, wherein T1 is between 4° C. and 10° C.; concentrating the solution by means of a reverse osmosis concentrator to produce a high Brix solution of about 15 to about 40 Brix; heating the high Brix solution of about 15 to about 40 Brix to temperature T2, wherein T2 is between 40° C. and 85° C.; and evaporating the high Brix solution by means of a vacuum evaporator at temperature T3 to produce the concentrated product of about 60 to about 70 Brix, wherein T3 is between 55° C. and 80° C. A system for concentrating a maple sap or sweet vegetal water solution is provided, as well as a concentrated product produced by the process of the present invention.

Abstract: The invention described here provides methods of efficiently treating vitamin C deficiency-related diseases and other conditions comprising the administration of pharmaceutical compositions comprising ascorbic acid compound(s), such as sodium ascorbate, and one or more pharmaceutically acceptable excipients (e.g., a carrier and optionally other agents, such as a tonicity agent, a chelator, or both). The methods comprise administration of such compositions in ready-to-use (RTU) form, provided in single unit dose packaging, wherein the compositions are stable when stored at 20° C. to 25° C.±2° C. for at least about 3 months. Compositions provided by the invention comprise an osmolality of between about 270 mOsm/kg to about 340 mOsm/kg and do not require dilution or further manipulation prior to use.

Abstract: Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium.

Abstract: A purified composition of steviol glycoside molecules is described. The composition imparts desirable taste, flavor and flavor modifying properties to food, beverages, and other consumable products.

Abstract: The present invention concerns a process for manufacturing an infant formula product involving: (a) subjecting an aqueous mixture having a protein component and a carbohydrate component to a heat treatment step; (b) mixing the aqueous mixture with a lipid component; (c) subjecting the aqueous mixture having the lipid component, the carbohydrate component and the heat-treated protein component to a homogenization and emulsification step to obtain a homogenized oil-in-water emulsion having a total solids content in the range of 45-73 wt %; (d) conveying the homogenized emulsion into an extruder, independently adding digestible carbohydrates and optionally dietary fibres to the extruder and extruding the contents of the extruder to obtain an extruded material; (e) preparing an infant formula product from the extruded material.

Abstract: Provided herein are compositions and methods for treating, preventing, and reducing the risk of obesity and related diseases and conditions. In particular, provided herein is a composition comprising a dry powder of fruits and vegetables and uses thereof.

Abstract: Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium.

Abstract: Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium.

Abstract: Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium.

Abstract: A fat composition comprises: greater than 70% by weight stearic acid; from 5% to 20% by weight oleic acid; and from 1% to 10% by weight palmitic acid; said percentages of acids referring to acids bound as acyl groups in glycerides in the fat composition and being based on the total weight of C8 to C24 fatty acids; and greater than 40% by weight of StStSt triglycerides and greater than 10% by weight of PSt2 triglycerides based on total triglycerides present in the composition, and a weight ratio of PSt2:StStSt triglycerides of less than 0.5, wherein P is palmitic acid and St is stearic acid. The fat may be used in a marinade.

Abstract: Novel mogrosides and methods for heir purification are provided herein. In addition, compositions comprising said novel mogrosides and methods for preparing the same are provided.

Abstract: A composition and method for ameliorating drug-seeking behavior in drug addicts who have stopped using the addicted-to drug and who have reestablished non-addict physiological chemical balance.

Abstract: A nutritional composition, typically an infant enterically administered nutritional composition, that comprises a milk fat globule membrane component, at least one human milk oligosaccharide and one additional component or a plurality of additional components where the additional component or components include DHA, ARA, Vitamin E, Vitamin C, and sphingomyelin.

Abstract: Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium.

Abstract: The present invention is related to a powderous composition which comprises lutein and which is used in infant food formulations or premixes for infant food formulations.

Abstract: Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium.

Abstract: Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium.

Abstract: Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium.

Abstract: Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium.

Abstract: Disclosed are nutritional compositions including human milk oligosaccharides in combination with long chain polyunsaturated fatty acids and/or carotenoids that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.

Abstract: Provided herein are shelf-stable protein food ingredients, food products comprising the shelf-stable protein food ingredients, methods of their production, and methods of their use. The shelf-stable protein food ingredients comprise cultured fungal biomass and a limited amount of water. Advantageously, the shelf-stable protein food ingredients can be stored, transported, and delivered within the food supply.

Abstract: Provided herein are shelf-stable protein food ingredients, food products comprising the shelf-stable protein food ingredients, methods of their production, and methods of their use. The shelf-stable protein food ingredients comprise cultured fungal biomass and a limited amount of water. Advantageously, the shelf-stable protein food ingredients can be stored, transported, and delivered within the food supply.

Abstract: The present invention provides a betaine compound for use in the prevention of obesity, excessive fat accumulation and/or metabolic disorders associated with either of the foregoing in a subject, wherein the prevention comprises administering the betaine compound directly to the subject during infancy or, alternatively, to the subject's mother during breast-feeding. Also provided are compositions comprising an effective amount of betaine compound together with one or more pharmaceutically or edible acceptable excipients and/or carriers for this use.

Abstract: Beverage compositions having enhanced shelf life are disclosed that contain juice-based compositions, vegetable extracts, ascorbic acid and glutathione. Glutathione at a pH of 4 or less is shown to inhibit browning and color degradation of the beverages without imparting a bad smell and taste that is usually associated with compositions with elevated amounts of glutathione.

Abstract: A vibration device includes a protective cover to transmit light with a predetermined wavelength, a first cylindrical body to hold the protective cover at one end, a plate spring to support the other end of the first cylindrical body, a second cylindrical body to support, at one end, a portion of the plate spring in an outer side portion of a portion that supports the first cylindrical body, and a vibrating body that is provided at the other end of the second cylindrical body to vibrate in an axial direction of the second cylindrical body.

Abstract: A method for alleviating a symptom of multiple sclerosis or other autoimmune or inflammatory disease includes a step of identifying a subject having multiple sclerosis or other autoimmune diseases. A fasting mimicking diet is administered to the subject for a first predetermined time period, the fasting mimicking diet providing less than 50% of the subject's normal caloric intake. A non-fasting diet is administered to the subject for a second time period following the first time period. The non-fasting diet provides the subject greater than 60 percent of the subject's normal caloric intake but a calorie intake necessary for the subject to return to a normal healthy weight.

Abstract: The present application relates to probiotic confection-based compositions comprising lactic acid-producing bacteria and oil-based compositions comprising the same.

Abstract: A system for modifying a nutrition requirement includes a computing device configured to obtain a user attribute, identify a nutrition requirement as a function of the user attribute, wherein identifying further comprises, receiving a nutrition training set, wherein the nutrition training set relates an aliment to a user attribute, and identifying the nutrition requirement as a function of a nutrition machine-learning process, receive a monitoring element from a monitoring device, modify the nutrition requirement, wherein modifying further comprises, receiving a modification training set, wherein the modification training set relates a monitoring element to a nutrition outcome, and modifying the nutrition requirement as a function of a modification machine-learning process, identify an aliment that fulfills the modified user nutrition requirement, and present an aliment on a display device.

Abstract: Embodiments of the invention provide pharmaceutical compositions and methods for preventing and treating disease and promoting the health in subjects at risk of cardiovascular disease and/or kidney disease. Additional embodiments of the present invention provide compositions and methods useful for treating and preventing a cardiovascular disease or a kidney disease.

Abstract: A vitamin supplement composition that includes a complex with enhanced bioavailability having a vitamin B complex, wherein the vitamin B complex includes: (a) a first vitamin, wherein the first vitamin comprises a form of vitamin B6; (b) a second vitamin, wherein the second vitamin comprises a form of vitamin B9; (c) a third vitamin, wherein the third vitamin comprises a form of vitamin B12; and (d) wherein the first vitamin, the second vitamin, and the third vitamin cooperate synergistically to enhance bioavailability of the same. The present invention further includes a method of administering a vitamin supplement composition to an individual having, for example, MTHFR deficiency.

Abstract: Disclosed in the present application are: a composition containing a green tea extract comprising at least one selected from the group consisting of 7 wt % or more of polysaccharides, less than 20 wt % of catechins, and 10 wt % or more of dietary fibers, relative to a total weight of the green tea extract, the composition having a use for blood glucose control; and a method for preparing the composition. The composition has not only effects of inhibiting activity of glucosidase and amylase but also effects of lowering blood glucose by inhibiting the glucose uptake in small intestinal cells.

Abstract: A solubilisate consisting of curcumin in a quantity of less than or equal to 10% by weight, preferably less than or equal to 7.5% by weight, particularly preferably 6% by weight, and at least one emulsifier having an HLB value in the range between 13 and 18, in particular polysorbate 80 or polysorbate 20 or a mixture of polysorbate 20 and polysorbate 80, wherein the average diameter of the micelles loaded with curcumin is between 5 nm and 40 nm, preferably between 6 nm and 20 nm, particularly preferably between 7 nm and 10 nm.

Abstract: A synthetic nutritional composition comprising a phospholipid and/or a metabolic precursor and/or metabolite thereof for use to promote, support or optimise de novo myelination, in particular the de novo myelination trajectory, and/or brain structure, and/or brain connectivity, and/or intellectual potential and/or cognitive potential, and/or learning potential and/or cognitive functioning in a subject, in particular a formula fed subject.

Abstract: A one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium is provided.

Abstract: A method of making a food product can include forming an emulsion containing a meat and a firming agent that is one or more of plasma, whole egg powder, guar gum, pea fiber, pea protein, carboxymethyl cellulose (CMC) or a modified cereal starch; directing the emulsion through a die to form a meat analog; cooking the meat analog with steam; and cutting the meat analog into thin flakes. The method can include cooling the meat analog before the cutting. The method can include mixing the thin flakes of the meat analog with jelly or gravy to form a blended food composition in which a ratio of the flakes to the jelly or gravy is about 30:70 to about 70:30.

Abstract: A fasting mimicking diet package providing daily meal portions for a predetermined number of days is provided. The fasting mimicking diet package includes a kale cracker composition, a first vegetable broth composition, a mushroom soup composition, a tomato soup composition, a quinoa-containing minestrone soup composition, a bean-containing minestrone soup composition, and a pumpkin soup composition. Characteristically, the daily meal portions are packaged into meal servings or into a total daily serving to be divided into meals.

Abstract: This invention relates generally to multivitamin extrudates. Their production as well as their use.

Abstract: A MATZHU is prepared by using leaves of Gramineae (Graminae) and Bambusoideae plant as raw materials. The MATZHU has a stable emerald color and an average powder particle size of 800 to 10,000 meshes. The MATZHU also has a total amount of dietary fiber of ?60%, a content of lignin of ?20% and a content of minerals of ?7%. The MATZHU includes at least three or more bamboo leaf characteristic components, such as orientin, isoorientin, vitexin, isovitexin, adenosine, ?-hydroxylysine and p-coumaric acid. The method for the MATZHU preparation includes, in turn, performing blanching and color protection, drying and superfine grinding the raw materials. By utilizing the thermal stability and the light stability of the MATZHU, the MATZHU may be used as a raw food material, a functional ingredient, or a dietary supplement.

Abstract: The present invention relates to a nutritional composition, for infants and young children (about 12 to 36 months) in which the sum of the triacylglycerols (TAG) sn-1(3) palmitic acid (PA), myristic acid (MA) and stearic acid (SA) constitutes less than 13.0% of the TAG. The composition promotes absorption of fatty acids and calcium in the gut, improves gut comfort, decreases abdominal pain associated with hard stool formation, promotes regular bowel movements and reduces the incidence and severity of constipation in infants and young children (up to the age of about three years old). The composition also promotes bone mineralization, increasing bone strength and bone mineral density.

Abstract: The present invention relates to compositions that enhances the palatability of pet foods designed for companion animals, e.g. dogs and cats, with renal insufficiency, and for methods of their manufacture.

Abstract: A threefold decrease in ?-amylase inhibition, increase in insulin secretion and glucose uptake increase by the pharmaceutical composition of several naturally occurring substances and vitamins were observed when compared to the control cells, and a c.a. 1-1.5 fold decrease when compared to the positive control. More specifically Mix A and Mix B applied together with VitaminD+K2 shows significant effect on increased insulin secretion and glucose uptake by cells.

Abstract: The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide for use in an infant or a young child for reducing and/or preventing later in life excessive fat mass accumulation and/or a health disorder related to excessive fat mass accumulation, wherein said fucosylated oligosaccharide has at least one fucose group attached by an alpha 1,3 linkage, at least one fucose group attached by an alpha 1,4 linkage, or combinations thereof. The invention also relates to nutritional composition for use to promote healthy growth.

Abstract: A composition and method for the prevention and/or improvement of dry eye syndrome, dryness of eye and/or stiff neck and shoulder, which contains bilberry fruit extract and is effective with less intake are provided. As one aspect of the present invention, the composition for the prevention or improvement of dry eye syndrome or dryness of eye contains a freeze-dried bilberry fruit extract. As another aspect of the present invention, the composition for the prevention or improvement of stiff neck and shoulder contains a freeze-dried bilberry fruit extract. As another aspect of the present invention, a composition for the prevention or improvement of dry eye syndrome, dryness of eye, and stiff neck and shoulder, contains a freeze-dried bilberry fruit extract. As another aspect of the present invention, a method using a bilberry fruit extract for the improvement of stiff neck and shoulder is provided.

Abstract: Composition and use of macro-minerals to lower postprandial glycemic response and reduce body weight are disclosed herein.

Abstract: Provided herein are compositions and methods for treating, preventing, and reversing malnutrition. In particular, provided herein are compositions and methods for facilitating cognitive repair and preventing obesity (e.g. in children).

Abstract: The invention relates to an adsorption system (10) for accumulating flavoring substances, comprising at least one working chamber (12) in which at least one sorption agent is provided as a stationary phase and can be subjected to a flavoring substance-containing fluid which can be conducted through the working chamber as a mobile phase for attaching flavoring substances, wherein a ratio of an average cross-sectional thickness to the total length of the at least one working chamber (12) is at most 0.3. The invention also relates to a method for operating such an adsorption system (10).

Abstract: The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide for use in an infant or young child for preventing a later in life health disorder by preventing premature adiposity rebound. The invention also relates to nutritional composition for use to promote healthy growth.

Abstract: Breath freshening formulations comprising licorice extract and menthol are provided. The breath freshening formulations can provide breath freshening in a confectionary product, through the synergy between licorice extract and menthol. Methods of reducing sulfurous compounds over time via a chewy confectionary product are also provided.

Abstract: The invention is a nutritional composition in unit dosage form for oral administration to an animal or human, which includes at least one ingredient from each of six biological Kingdoms selected from the group consisting of animals, plants, fungi, bacteria, protist and archaea. Each ingredient is co-admixed with every other said ingredient without further addition of synthetic excipients or fillers, and is typically formulated in dried powder form as a drink mix, food or beverage additive or as the fill for hard or soft capsules or other dosage forms including tablets (the compositions of the invention can generally be tableted without addition of ingredients beyond the nutrients themselves).