Plant Cell Or Cell Line, Per Se, Contains Exogenous Or Foreign Nucleic Acid Patents (Class 435/419)
-
Patent number: 8940978Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH741796. The invention thus relates to the plants, seeds and tissue cultures of the variety CH741796, and to methods for producing a corn plant produced by crossing a corn plant of variety CH741796 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH741796.Type: GrantFiled: April 26, 2012Date of Patent: January 27, 2015Assignee: Monsanto Technology LLCInventors: Sandeep Bhatnagar, Mark J. Brinkman, Kevin D. Eichelberger, Sarah Gehlhar, Gregory J. Holland, Daniel J. Lubich, Jeffrey L. McElroy, Laron L. Peters, Duane A. Potrzeba, Hector Ramirez de Leon
-
Patent number: 8940979Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH048856. The invention thus relates to the plants, seeds and tissue cultures of the variety CH048856, and to methods for producing a corn plant produced by crossing a corn plant of variety CH048856 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH048856.Type: GrantFiled: April 26, 2012Date of Patent: January 27, 2015Assignee: Monsanto Technology LLCInventors: James R. Larkins, Gregory J. Holland
-
Patent number: 8940976Abstract: The invention provides seed and plants of tomato hybrid PX 02461513 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of tomato hybrid PX 02461513 and the parent lines thereof, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.Type: GrantFiled: April 6, 2012Date of Patent: January 27, 2015Assignee: Seminis Vegetable Seeds, Inc.Inventors: Teresa Beck Bunn, Giulio Bile
-
Publication number: 20150026844Abstract: Transgenic plants, and a method for making the same, wherein genes encoding the enzyme luciferase and its corresponding substrate luciferin are incorporated into a native plant genome. Once transformed into plant cells, these genes may be regulated such that under certain endogenous or exogenous conditions, their expression in the mature plant results in bioluminescence. Different luciferin/luciferase complexes and/or mechanisms of regulation may be utilized for these transgenic plants, depending on a variety of factors such as plant species and the circumstances under which a biolmuniescent reaction is desired. Phototransformation may be utilized to vary the wavelength of light emitted from the mature plant.Type: ApplicationFiled: September 25, 2014Publication date: January 22, 2015Inventor: Bruce Eric Hudkins
-
Publication number: 20150025227Abstract: Disclosed is an IgG Fc fragment useful as a drug carrier. A recombinant vector expressing the IgG Fc fragment, a transformant transformed with the recombinant vector, and a method of preparing an IgG Fc fragment are disclosed. When conjugated to a certain drug, the IgG Fc fragment improves the in vivo duration of action of the drug and minimizes the in vivo activity reduction of the drug.Type: ApplicationFiled: July 9, 2014Publication date: January 22, 2015Applicant: HANMI SCIENCE CO., LTD.Inventors: Sung Youb JUNG, Jin Sun Kim, Geun Hee Yang, Se Wang Kwon, Gwan Sun Lee
-
Publication number: 20150026840Abstract: To produce a bacterial microcompartment shell, or a designed shell based on naturally occurring bacterial microcompartment shells in a new host organism, a synthetic operon is constructed that contains the desired shell protein genes and translation efficiency is controlled by host specific ribosomal binding sites. Proteins or other molecules can be encapsulated in the microcompartment shells by various methods described herein. The constructs can also be used to express self-assembling sheets comprised of shell proteins.Type: ApplicationFiled: March 14, 2014Publication date: January 22, 2015Applicant: The Regents of the University of CaliforniaInventors: Cheryl A. Kerfeld, Jonathan K. Lassila, James N. Kinney
-
Publication number: 20150024009Abstract: The invention provides an isolated genetically modified non-mammalian organism, wherein the activity of acyl-CoA:sterol acyltransferase/sterol O-acyltransferase (EC 2.3.1.26) and/or diacylglycerol acyltransferase/diacylglycerol O-acyltranferase (EC 2.3.1.20) and/or lecithin cholesterol acyl transferase/phospholipid: diacylglycerol acyltransferase (EC 2.3.1.158) and/or acyl CoA-wax alcohol acyltransferase (EC 2.3.1.75) is reduced or abolished in comparison with a corresponding wildtype organism, methods of use of such an organism, shuttle vehicles for making such an organism and methods for producing such an organism.Type: ApplicationFiled: September 19, 2014Publication date: January 22, 2015Applicant: ORGANOBALANCE GMBHInventors: Christine Lang, Andreas Raab
-
Publication number: 20150023967Abstract: The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain, wherein the first binding domain is capable of binding to epitope cluster3 of BCMA, and the second binding domain is capable of binding to the Tcell CD3 receptor complex. Moreover, the invention provides a nucleic acid sequence encoding the binding molecule, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention provides a process for the production of the binding molecule of the invention, a medical use of said binding molecule and a kit comprising said binding molecule.Type: ApplicationFiled: November 15, 2012Publication date: January 22, 2015Inventors: Peter Kufer, Tobias Raum, Patrick Hoffmann, Roman Kischel, Ralf Lutterbuese, Doris Rau, Paul Adam, Eric Borges, Barbara Hebeis, Susanne Hipp
-
Publication number: 20150023995Abstract: The present invention provides polypeptides having a composite amino acid sequence derived from a consensus sequence representing the capsid proteins of two or more circulating strains of a non-enveloped virus. In particular, the invention provides virus-like particles comprising at least one composite polypeptide. Such virus-like particles have antigenic epitopes of two or more circulating strains of a non-enveloped virus and produce an increase in antisera cross-reactivity to one or more circulating strains of the non-enveloped virus. Methods of making composite virus-like particles and vaccine formulations comprising composite virus-like particles are also disclosed.Type: ApplicationFiled: July 25, 2014Publication date: January 22, 2015Applicant: TAKEDA VACCINES, INC.Inventors: Charles RICHARDSON, Robert F. BARGATZE, Joel HAYNES, Bryan STEADMAN
-
Publication number: 20150024439Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.Type: ApplicationFiled: September 29, 2014Publication date: January 22, 2015Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
-
Publication number: 20150026843Abstract: The present invention relates to isolated polypeptides having proteaseactivity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptidesin e.g. animal feed and detergents.Type: ApplicationFiled: December 20, 2012Publication date: January 22, 2015Inventors: Tine Hoff, Carsten Sjoeholm, Peter Rahbek Oestergaard, Katrine Pontoppidan
-
Publication number: 20150023958Abstract: A fusion polypeptide capable of binding simultaneously to angiopoietin 2, VEGF-C and VEGF-D; or capable of binding simultaneously to VEGF-C and VEGF-D, and methods for the preparation and use thereof.Type: ApplicationFiled: July 21, 2014Publication date: January 22, 2015Inventors: Kwang Hoon LEE, Hyung-Chan Kim, Sang Yeul Han, Seok Kyun Kim, Kyung Eun Kim
-
Publication number: 20150025124Abstract: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lepidoptera order, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides encoding polypeptides from specific protein families and various target polynucleotides set forth in SEQ ID NOS: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, or 50 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity).Type: ApplicationFiled: September 30, 2014Publication date: January 22, 2015Inventors: RAFAEL HERRMANN, MICHAEL LASSNER, ALBERT L. LU, MARK EDWARD NELSON, JAMES KEVIN PRESNAIL, JANET A. RICE
-
Publication number: 20150025228Abstract: Disclosed is an IgG Fc fragment useful as a drug carrier. A recombinant vector expressing the IgG Fc fragment, a transformant transformed with the recombinant vector, and a method of preparing an IgG Fc fragment are disclosed. When conjugated to a certain drug, the IgG Fc fragment improves the in vivo duration of action of the drug and minimizes the in vivo activity reduction of the drug.Type: ApplicationFiled: July 9, 2014Publication date: January 22, 2015Applicant: HANMI SCIENCE CO., LTD.Inventors: Sung Youb JUNG, Jin Sun Kim, Geun Hee Yang, Se Chang Kwon, Gwan Sun Lee
-
Patent number: 8937232Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH858223. The invention thus relates to the plants, seeds and tissue cultures of the variety CH858223, and to methods for producing a corn plant produced by crossing a corn plant of variety CH858223 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH858223.Type: GrantFiled: April 27, 2012Date of Patent: January 20, 2015Assignee: Monsanto Technology LLCInventor: Jon Popi
-
Patent number: 8937226Abstract: The invention provides seed and plants of tomato hybrid PS02326502 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of tomato hybrid PS02326502 and the parent lines thereof, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.Type: GrantFiled: January 5, 2012Date of Patent: January 20, 2015Assignee: Seminis Vegetable Seeds, Inc.Inventor: Giulio Bile
-
Patent number: 8937230Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH806961. The invention thus relates to the plants, seeds and tissue cultures of the variety CH806961, and to methods for producing a corn plant produced by crossing a corn plant of variety CH806961 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH806961.Type: GrantFiled: April 26, 2012Date of Patent: January 20, 2015Assignee: Monsanto Technology LLCInventors: Sandeep Bhatnagar, Mark J. Brinkman, Kevin D. Eichelberger, Sarah Gehlhar, Gregory J. Holland, Daniel J. Lubich, Jeffrey L. McElroy, Laron L. Peters, Duane A. Potrzeba, Hector Ramirez de Leon
-
Patent number: 8937217Abstract: Isolated nucleic acid fragments comprising precursor miRNAs, and artificial miRNAs and their use in down-regulating gene expression are described.Type: GrantFiled: December 16, 2008Date of Patent: January 20, 2015Assignee: E. I. du Pont de Nemours and CompanyInventor: Brian McGonigle
-
Patent number: 8937225Abstract: The invention provides seed and plants of tomato hybrid PS02450650 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of tomato hybrid PS02450650 and the parent lines thereof, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.Type: GrantFiled: January 5, 2012Date of Patent: January 20, 2015Assignee: Seminis Vegetable Seeds, Inc.Inventor: Teresa Beck Bunn
-
Patent number: 8936937Abstract: Modified expression vectors, including Tobacco Mosaic Virus (TMV) expression vectors, methods for modifying such vectors, and uses of the same are disclosed.Type: GrantFiled: January 28, 2008Date of Patent: January 20, 2015Assignee: The Ohio State University Research FoundationInventor: John A. Lindbo
-
Patent number: 8937218Abstract: A transformed soybean plant having a gene encoding a modified seed storage protein introduced therein, obtained by inserting a gene encoding an Alzheimer's disease vaccine to a variable region(s) of a gene encoding a wild-type seed storage protein, is produced, and said vaccine is produced and accumulated in the seeds thereof.Type: GrantFiled: November 26, 2009Date of Patent: January 20, 2015Assignee: Hokko Chemical Industry Co., Ltd.Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Masao Ishimoto, Mikio Shoji, Takeshi Kawarabayashi, Yasuko Utsumi
-
Patent number: 8937219Abstract: The present invention pertains to a novel and extensive analytical platform for selecting genes with a possible commercial phenotype from a large group of candidate genes identified using tools in bioinformatics, data from EST sequencing and DNA array. An aspect of the invention provides methods of producing a transgenic plant having an increased growth compared to its wild type. The method comprises altering in the plant the level of a gene product of at least one gene specifically expressed during different phases of wood formation. This may be done with transgenic methods or by specific crossing methods. Further aspects of the invention provide a plant cell or plant progeny and wood having modulated gene expression according to the invention. Other aspects pertain a DNA construct comprising a nucleotide sequence of the invention and a plant cell or plant progeny comprising the DNA construct.Type: GrantFiled: December 18, 2008Date of Patent: January 20, 2015Assignee: Sweetree Technologies ABInventors: Magnus Hertzberg, Rishikeshi Bhalerao, David Jonsén, Linus Möller, Pär Jonsson
-
Patent number: 8937231Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH327469. The invention thus relates to the plants, seeds and tissue cultures of the variety CH327469, and to methods for producing a corn plant produced by crossing a corn plant of variety CH327469 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH327469.Type: GrantFiled: April 26, 2012Date of Patent: January 20, 2015Assignee: Monsanto Technology LLCInventors: Sandeep Bhatnagar, Mark J. Brinkman, Kevin D. Eichelberger, Sarah Gehlhar, Gregory J. Holland, Daniel J. Lubich, Jeffrey L. McElroy, Laron L. Peters, Duane A. Potrzeba, Hector Ramirez de Leon
-
Publication number: 20150017095Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.Type: ApplicationFiled: July 9, 2014Publication date: January 15, 2015Inventors: Tariq Ghayur, Jijie Gu, Peter Isakson
-
Publication number: 20150020234Abstract: The invention relates to isolated nucleic acids encoding a feruloyl-CoA:monolignol transferase and feruloyl-CoA:monolignol transferase enzymes. The isolated nucleic acids and/or the enzymes enable incorporation of monolignol ferulates into the lignin of plants, where such monolignol ferulates include, for example, p-coumaryl ferulate, coniferyl ferulate, and/or sinapyl ferulate. The invention also includes methods and plants that include nucleic acids encoding a feruloyl-CoA:monolignol transferase enzyme and/or feruloyl-CoA:monolignol transferase enzymes.Type: ApplicationFiled: October 4, 2012Publication date: January 15, 2015Inventors: Curtis Wilkerson, John Ralph, Saunia Withers
-
Publication number: 20150017728Abstract: The present invention provides compositions and methods for targeted cleavage of cellular chromatin in a region of interest and/or homologous recombination at a predetermined site in cells. Compositions include fusion polypeptides comprising a TAL effector binding or a zinc finger domain and an I-TevI homing endonuclease cleavage domain as well as nucleic acid sequence encoding the same. The use of the I-TevI domain allows for monomer endonuclease sequences to achieve cleavage of cellular chromatin and represents an advantage over prior endonucleases which require self-dimerization, and two nucleases with appropriate spacers.Type: ApplicationFiled: September 19, 2012Publication date: January 15, 2015Inventors: Bing Yang, Ting Li, Sheng Huang
-
Publication number: 20150018531Abstract: Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.Type: ApplicationFiled: February 22, 2013Publication date: January 15, 2015Applicant: STEM CENTRX, INC.Inventors: Laura Saunders, Scott J. Dylla, Orit Foord, Robert A. Stull, Michael Torgov, Hui Shao, David Liu
-
Publication number: 20150017695Abstract: The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.Type: ApplicationFiled: September 30, 2014Publication date: January 15, 2015Inventors: Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, John M. Gruber, Anke Krebber, Gjalt W. Huisman
-
Publication number: 20150020242Abstract: A novel promoter useful for altering the color of flowers of a plant, which is selected from the group consisting of: (1) a nucleic acid which comprises the nucleotide sequence represented by SEQ ID NO: 20, SEQ ID NO: 12 or SEQ ID NO: 21; and (2) a nucleic acid which maintains the same promoter activity as that of the nucleotide sequence represented by SEQ ID NO: 20, SEQ ID NO: 12 or SEQ ID NO: 21, and which comprises a nucleotide sequence that is produced by modifying the original nucleotide sequence by the addition, deletion and/or substitution of one or several nucleotide sequences, or can hybridize with a nucleotide acid comprising a nucleotide sequence complementary to the original nucleotide sequence under highly stringent conditions, or has a 90% or more sequence identity to the original nucleotide sequence.Type: ApplicationFiled: February 19, 2013Publication date: January 15, 2015Applicant: SUNTORY HOLDINGS LIMITEDInventors: Yoshikazu Tanaka, Yukihisa Katsumoto
-
Publication number: 20150020241Abstract: The present invention provides non-coding regulatory element polynucleotide molecules isolated from the S-adenosyl methionine synthetase (SAMS3) gene of Arabidopsis thaliana and useful for expressing transgenes in plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the Arabidopsis thaliana regulatory polynucleotide sequences, and methods for preparing and using the same.Type: ApplicationFiled: June 6, 2014Publication date: January 15, 2015Inventors: Wei Wu, Qi Wang, Michael Edgerton, Kim Beazley, Jill Deikman, Michael W. Petersen, Bei Zhang
-
Publication number: 20150018532Abstract: The invention relates to antibodies to Aspergillus species and to methods of producing those antibodies. The invention also relates to the use of such antibodies in identifying the presence of the Aspergillus species and to methods of treating an infection with the Aspergillus species.Type: ApplicationFiled: June 6, 2014Publication date: January 15, 2015Applicant: UNIVERSITY OF EXETERInventor: Christopher THORNTON
-
Publication number: 20150020238Abstract: The present invention provides a synthetic gene encoding the human enterokinase light chain protein, a recombinant vector comprising the synthetic gene encoding the protein, a plant cell transformed with the recombinant vector, a method for producing the human enterokinase light chain protein in a plant by using the recombinant vector, a method for producing a plant producing the human enterokinase light chain protein by transforming a plant cell with the recombinant vector, a plant producing the human enterokinase light chain protein which is produced by the method, and a seed thereof, and a composition for large-scale production of the human enterokinase light chain protein in a plant, in which the composition comprises the synthetic gene encoding the human enterokinase light chain protein.Type: ApplicationFiled: July 19, 2012Publication date: January 15, 2015Applicant: NBM CO., LTD.Inventor: Tae Ho Kwon
-
Patent number: 8933307Abstract: The present invention is in the field of soybean variety WN0913499 breeding and development. The present invention particularly relates to the soybean variety WN0913499 and its progeny, and methods of making WN0913499.Type: GrantFiled: March 17, 2013Date of Patent: January 13, 2015Assignee: Syngenta Participations AGInventors: Kevin Chris Threlkeld, Keith Merle Bilyeu
-
Patent number: 8933297Abstract: The invention provides Nicotiana benthamiana mutant plants which are incapable of forming xylosyl-structures on glycoproteins. In addition, the invention provides methods for the production of heterologous glycoproteins in said mutant plants.Type: GrantFiled: June 10, 2010Date of Patent: January 13, 2015Assignee: Icon Genetics GmbHInventors: Koen Weterings, Gerben Van Eldik
-
Patent number: 8933306Abstract: The present invention is in the field of soybean variety OW1012750 breeding and development. The present invention particularly relates to the soybean variety OW1012750 and its progeny, and methods of making OW1012750.Type: GrantFiled: March 15, 2013Date of Patent: January 13, 2015Assignee: Syngenta Participations AGInventor: Kurt Milan Lindenbaum
-
Patent number: 8933302Abstract: The present invention relates to the isolation of Jatropha curcas curcin genes and tissue-specific promoters and to the production of curcin-deficient Jatropha plants. More specifically, the present invention relates to the isolation of Jatropha curcas Curcin 1, Curcin 2 and Curcin 2 A. The present invention further relates to of the Curcin 1, Curcin 2 A and Curcin 2 genes and more particularly to tissue specific promoters of the Curcin 1 and Curcin 2A genes. The present invention further relates to production of curcin-deficient transgenic jatropha plants by using RNAi technology to suppress curcin gene expression.Type: GrantFiled: June 2, 2010Date of Patent: January 13, 2015Assignee: Temasek Life Sciences Laboratory LiimitedInventors: Zhong Chao Yin, Li Fang Wu, Hui Zhu Mao, Cheng Xiang Qiu
-
Publication number: 20150010961Abstract: The present invention relates to a family 5 glycoside hydrolase variant having endoglucanase activity, polynucleotides encoding the family 5 glycoside hydrolase variant, vectors, host cells comprising the polynucleotides, and methods for using the family 5 glycoside hydrolase variant.Type: ApplicationFiled: September 25, 2014Publication date: January 8, 2015Inventors: John Poland, Justin T. Stege
-
Publication number: 20150013030Abstract: The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having improved tolerance to drought, shade, and low nitrogen conditions, as compared to wild-type or reference plants.Type: ApplicationFiled: March 28, 2014Publication date: January 8, 2015Applicant: Mendel Biotechnology, Inc.Inventors: Jacqueline E Heard, Jose Luis Riechmann, Robert A Creelman, Oliver J Ratcliffe, Roger D Canales, Peter P Repetti, Roderick W Kumimoto, Neal I Gutterson, T. Lynne Reuber, Omaira Pineda, Cai-Zhong Jiang, Karen S Century, Luc Adam, James Z Zhang, Frederick D Hempel, Jeffrey M Libby
-
Publication number: 20150013031Abstract: The present invention relates to methods and compositions for improving the efficiency of Agrobacterium- and Rhizobium-mediated plant cell transformation by use of additional transformation enhancer sequences, such as overdrive or TSS sequences, operably linked to a T-DNA border sequence on a recombinant construct that comprises T-DNA.Type: ApplicationFiled: June 3, 2014Publication date: January 8, 2015Inventors: Larry A. Gilbertson, Xudong Ye
-
Publication number: 20150010547Abstract: Recombinant antibodies (including binding fragments thereof) that bind IgE are described, along with compositions and methods of using the same in the treatment of subjects in need thereof, including subjects afflicted with atopic dermatitis, allergic rhinitis, allergic conjunctivitis, urticaria, gastro-intestinal inflammation, or oral-pharyngeal inflammation. In some embodiments, the antibody is a single chain variable fragment (scFv) or a disulfide linked variable fragment (sdFv). In some embodiments, the subject is a dog, cat, or horse.Type: ApplicationFiled: January 29, 2013Publication date: January 8, 2015Inventor: Bruce Hammerberg
-
Publication number: 20150013033Abstract: The present invention provides an expression cassette containing a polynucleotide coding sequence for a hydroxycinnamoyl-CoA hydratase-lyase (HCHL), which is operably linked to a heterologous promoter. Also provided are methods of engineering plants that have reduced lignification, as well as cells, plant parts, and plant tissues from such engineered plants.Type: ApplicationFiled: July 13, 2012Publication date: January 8, 2015Applicant: The Regents of the University of CaliforniaInventors: Dominique Loqué, Amyerick Guillaume Eudes
-
Publication number: 20150010532Abstract: The invention relates to recombinant nucleic acid and polypeptides encoding collagenase I and collagenase II, methods for the preparation thereof and methods for the use thereof. The invention also encompasses methods related to releasing a composition comprising collagenase prior to therapeutic administration.Type: ApplicationFiled: July 11, 2014Publication date: January 8, 2015Inventor: Wayne K. Herber
-
Publication number: 20150010527Abstract: Plant-expressed human recombinant DNase proteins, nucleic acid constructs for expression of the human recombinant DNase I in plant cells, cells expressing the nucleic acid construct and therapeutic uses thereof are disclosed. Particularly, compositions and methods for treating pulmonary and/or respiratory conditions by inhalation of the plant-expressed human recombinant DNase I are provided.Type: ApplicationFiled: January 31, 2013Publication date: January 8, 2015Inventors: Yoseph Shaaltiel, Uri Hanania, Tali Kizhner, Yulia Matiuhin, Liat Fux, Avidor Shulman
-
Patent number: 8927816Abstract: The present invention is in the field of soybean variety BK1011572 breeding and development. The present invention particularly relates to the soybean variety BK1011572 and its progeny, and methods of making BK1011572.Type: GrantFiled: March 15, 2013Date of Patent: January 6, 2015Assignee: Syngenta Participations AGInventor: Kurt Milan Lindenbaum
-
Patent number: 8927822Abstract: A potato cultivar designated ‘FL 2312’ is disclosed. The invention relates to tubers and seeds of potato cultivar ‘FL 2312’, to plants of potato cultivar ‘FL 2312’, to plant parts of potato cultivar ‘FL 2312’ and to methods for producing progeny of potato cultivar ‘FL 2312’. The invention relates to methods for producing a potato plant containing in its genome one or more transgenes and to the transgenic potato plants and plant parts produced by those methods. This invention relates to potato cultivars or breeding cultivars and plant parts derived from potato variety ‘FL 2312’, to methods for producing other potato cultivars, lines or plant parts derived from potato cultivar ‘FL 2312’ and to potato plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid potato tubers, seeds, plants and plant parts produced by crossing potato cultivar ‘FL 2312’ with another potato cultivar.Type: GrantFiled: September 14, 2012Date of Patent: January 6, 2015Assignee: Frito-Lay North America, Inc.Inventor: Robert W. Hoopes
-
Patent number: 8927821Abstract: The present invention is in the field of soybean variety WN1013087 breeding and development. The present invention particularly relates to the soybean variety WN1013087 and its progeny, and methods of making WN1013087.Type: GrantFiled: March 18, 2013Date of Patent: January 6, 2015Assignee: Syngenta Participations AGInventors: Kevin Chris Threlkeld, Keith Merle Bilyeu
-
Patent number: 8927811Abstract: Polynucleotides and polypeptides incorporated into expression vectors have been introduced into plants and were ectopically expressed. The polypeptides of the invention regulate transcription in these plants and have been shown to confer at least one regulatory activity that results in increased size, biomass, growth rate, and/or yield as compared to a control plan.Type: GrantFiled: August 3, 2007Date of Patent: January 6, 2015Assignee: Mendel Biotechnology, Inc.Inventors: Oliver J. Ratcliffe, Peter P. Repetti, Neal I. Gutterson, Robert A. Creelman
-
Patent number: 8927820Abstract: The present invention is in the field of soybean variety SJ1012477 breeding and development. The present invention particularly relates to the soybean variety SJ1012477 and its progeny, and methods of making SJ1012477.Type: GrantFiled: March 18, 2013Date of Patent: January 6, 2015Assignee: Syngenta Participations AGInventor: Roger L McBroom
-
Patent number: 8927285Abstract: Disclosed are: a microalga highly capable of producing aliphatic hydrocarbons of 16 to 26 carbon atoms; a process for producing oil, which comprises a step of culturing the microalga; oil collected from the microalga; a fuel produced from the microalga; and a method for fixing carbon dioxide, which comprises a step of culturing the microalga. Specifically disclosed is a microalga belonging to the genus Navicula, which is capable of producing aliphatic hydrocarbons of 16 to 26 carbon atoms. More specifically disclosed is a microalga, Navicula oiliticus strain JPCC DA0580 (FERM BP-11201).Type: GrantFiled: March 10, 2010Date of Patent: January 6, 2015Assignee: Electric Power Development Co., Ltd.Inventor: Mitsufumi Matsumoto
-
Patent number: 8927812Abstract: The present invention relates to methods for generating or increasing resistance to at least one fungi, in particular soy bean rust, in a plant or a part of a plant by the expression of RNA which is at least partial complementary and/or identical to the STM1-gene, wherein the RNA is capable to provide ds-RNA and/or siRNA and/or miRNA. Moreover, the invention relates to respective plants, parts thereof and vector constructs capable to provide such RNA and the use of such vector constructs to provide fungal resistant plants.Type: GrantFiled: December 6, 2010Date of Patent: January 6, 2015Assignee: BASF Plant Science Company GmbHInventor: Holger Schultheiβ