Synthetic Or Natural Resin Patents (Class 436/85)
  • Patent number: 11814460
    Abstract: The present disclosure provides pyridyl hydroxyl amine catalyst compounds and systems containing the compounds. The present disclosure is also directed to polymerization processes to produce polyolefin polymers from catalyst systems including one or more olefin polymerization catalysts, at least one activator, and an optional support.
    Type: Grant
    Filed: October 19, 2021
    Date of Patent: November 14, 2023
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Alex E. Carpenter, Danielle G. Singleton, Tzu-Pin Lin
  • Patent number: 11649256
    Abstract: The present disclosure provides catalyst compounds represented by Formula (I): where Q is OR13, SR13, NR13R14, PR13R14, or a heterocyclic ring; each R1-14 is independently hydrogen, C1-C40 hydrocarbyl, substituted C1-C40 hydrocarbyl, a heteroatom, or a heteroatom-containing group, or multiple R1-14 are joined together to form a C4-C62 cyclic, heterocyclic, or polycyclic ring structure, or combination(s) thereof; each X1 and X2 is independently C1-C20 hydrocarbyl, substituted C1-C20 hydrocarbyl, a heteroatom, or a heteroatom-containing group, or X1 and X2 join together to form a C4-C62 cyclic, heterocyclic, or polycyclic ring structure; and Y is a hydrocarbyl. The present disclosure also provides catalyst systems including an activator, a support, and a catalyst of the present disclosure. The present disclosure also provides polymerization processes including introducing olefin monomers to a catalyst system.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: May 16, 2023
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Gursu Culcu, Catherine A. Faler, Crisita Carmen H. Atienza, David A. Cano, John R. Hagadorn
  • Patent number: 11619590
    Abstract: A composition and method for the photometric determination of a film-forming amine in liquid by adding an indicator reagent to an aqueous system that is pH dependent, combining a water soluble non-ionic polymer to modify the physical properties of the aqueous system, and adding an acidic buffer to said aqueous system to lower pH and activate said indicator, said water soluble polymer keeping the filming amine/indicator complex in solution despite the acidic buffer and preventing it from precipitating out.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: April 4, 2023
    Assignee: Taylor Water Technologies LLC
    Inventors: Brian Trice, Heather Drake
  • Patent number: 11454619
    Abstract: Systems for quantifying one or more target analyte concentrations in a process solution are provided and can be used, for example, in methods for quantifying a target analyte concentration. These systems and methods include continuous and batchwise automated titration methods that use titration chemistries to measure the target analyte concentration in the process solution using a multiwavelength detector. The methods provide for efficient and robust automated titration methods for a variety of target analytes and can include methods that analyze more than one analyte and that provide for a dynamic range for measurement of more than one target analyte concentration.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: September 27, 2022
    Assignee: Ecolab USA Inc.
    Inventors: Paul R. Kraus, John Wilhelm Bolduc, Robert J. Ryther
  • Patent number: 11285465
    Abstract: The present disclosure provides catalyst compounds including a nonsymmetric bridged amine bis(phenolate), catalyst systems including such, and uses thereof. Catalyst compounds, catalyst systems, and processes of the present disclosure can provide high comonomer content and high molecular weight polymers having narrow Mw/Mn values, contributing to good processability for the polymer itself and for the polymer used in a composition.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: March 29, 2022
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Crisita Carmen H. Atienza, David A. Cano, Catherine A. Faler, Margaret T. Whalley
  • Patent number: 11090625
    Abstract: An apparatus and a method to withdraw samples from a polymerization plant using a defined sequence of steps combined with locking devices for valves opened by a single key.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: August 17, 2021
    Assignee: Basell Poliolefine Italia S.r.l.
    Inventors: Pier Luigi Di Federico, Martin Andries De Zeeuw
  • Patent number: 11072687
    Abstract: Disclosed is a curable sealant composition including: (i) a thiol-terminated prepolymer and/or monomers thereof, wherein the thiol-terminated prepolymer is a polythioether or a polysulfide; (ii) an “ene” crosslinker having a molecular weight of about 100 to about 5000; and (iii) a pH indicator molecule including a quantum dot functionalized with a pH-responsive ligand. Methods for determining a sufficient cure state of a composition by combining the thiol-terminated prepolymer and/or monomers thereof and the “ene” crosslinker with a pH indicator molecule, including a quantum dot functionalized with a pH-responsive ligand, and (ii) then subjecting a resultant mixture of (i) to curing conditions until the mixture changes its color are also disclosed.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: July 27, 2021
    Assignee: THE BOEING COMPANY
    Inventors: Katherine L. Frank, Andrew M. Zweig
  • Patent number: 10557044
    Abstract: This invention provides slippery liquid-infused porous surfaces (SLIPS) using nanoporous or microporous and chemically reactive polymer multilayers. This approach permits fabrication of slippery anti-fouling coatings on complex surfaces and provides new means to manipulate the mobilities of contacting aqueous fluids. The results expand the range of tools that can be used to manipulate the behaviors of SLIPS and open the door to new applications of this emerging class of soft materials.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: February 11, 2020
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: David Lynn, Uttam Manna, Matthew Carter
  • Patent number: 9851342
    Abstract: The present invention provides a method of deterioration analysis that enables detailed analysis of the deterioration, especially of the surface, of a polymer material containing at least two diene polymers. The present invention relates to a method of deterioration analysis including: irradiating a polymer material containing at least two diene polymers with high intensity x-rays; and measuring x-ray absorption while varying the energy of the x-rays, to analyze the deterioration of each diene polymer.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: December 26, 2017
    Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventors: Fusae Kaneko, Hiroyuki Kishimoto
  • Patent number: 9598668
    Abstract: A substrate having a pattern of two or more materials exhibiting different grafting efficiencies for a temperature-responsive polymer that varies its interaction with water in a temperature range of 0 to 80° C. by electron beam irradiation under the same conditions is grafted with the temperature-responsive polymer by simultaneously irradiating the surfaces of the materials with electron beams to obtain a temperature-responsive cell culture substrate. According to this method, a temperature-responsive cell culture substrate having a surface (1) that allows cells to adhere thereto and to grow thereon during cell culturing and that allows the adhering and grown cells to be detached therefrom by changing the culturing temperature and a surface (2) that does not allow the cells to adhere thereto at all can be obtained by a simple process.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: March 21, 2017
    Assignee: CELLSEED INC.
    Inventors: Manabu Mizutani, Hiroya Watanabe, Yuriko Kitano
  • Publication number: 20150147816
    Abstract: Provided is a method of evaluating a resin capable of quantitatively evaluating a deterioration degree of the resin with high accuracy and ease. The method includes evaluating the resin based on a shift of a characteristic peak representing a deterioration degree of the resin, the peak being observed in thermal analysis of the resin by a temperature increase, to lower temperatures.
    Type: Application
    Filed: November 19, 2014
    Publication date: May 28, 2015
    Applicant: CHIYODA CORPORATION
    Inventors: Zhixiong You, Ryuichi Kanai, Yoichi Umehara, Takeshi Minami
  • Patent number: 8946327
    Abstract: Provided is a method for producing synthetic amylospheroids efficiently, the method including agitating a liquid containing amyloid ?-peptides in the presence of a plasticizer. Amylospheroid refers to an assembly of amyloid ?-peptides that selectively can induce cell death of functionally mature neurons. Amylospheroid is considered to play a central role in the development of Alzheimer's disease and dementia with Lewy bodies.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: February 3, 2015
    Assignee: Tao Health Life Pharma Co., Ltd.
    Inventor: Minako Hoshi
  • Publication number: 20150031138
    Abstract: The present invention provides materials, devices, and methods related to determination of an analyte. In some embodiments, an analyte may be determined by monitoring, for example, a change in an optical signal of a luminescent material (e.g., particle) upon exposure to an analyte. The present invention may be particularly advantageous in that some embodiments may comprise an emissive species useful as an internal reference standard. Methods of the invention may also be useful in the quantitative determination of an analyte. In some cases, the present invention may allow for selective determination of an analyte.
    Type: Application
    Filed: August 8, 2014
    Publication date: January 29, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy M. Swager, Jessica H. Liao
  • Patent number: 8940538
    Abstract: The present invention relates to an apparatus for quantifying the binding and dissociation kinetics of molecular interactions of small molecular bio materials with high sensitivity almost without the influence of a change in the reflective index resulting from a buffer solution by making polarized incident light incident on the binding layer of a bio material, formed in a thin dielectric film, so that the polarized incident light satisfies a p-wave non-reflecting condition and a quantifying method using the same.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: January 27, 2015
    Assignee: Korea Research Institute of Standards and Science
    Inventors: Hyun Mo Cho, Gal Won Che, Yong Jai Cho
  • Publication number: 20150017731
    Abstract: Disclosed is a test apparatus of accelerated photo-degradation measuring a degradation caused by photo-degradation in a material or a product by light containing UV light and visible light that simulate the solar light-inducing degradation. The apparatus includes a light irradiating unit configured to irradiate light using at least one electrodeless plasma lamp; a light condensing unit configured to collect light emitted from the light irradiating unit and irradiate the light uniformly into the surface of the specimen for the material or the product; and a specimen holder configured to fix the specimen, and the specimen holder being fixed at a predetermined position or rotated. Further, the at least one electrodeless plasma lamp generates light having a light power spectrum similar to a solar light in a region of UV light and short-wavelength visible light corresponding to a range of about 300-500 nm.
    Type: Application
    Filed: January 16, 2013
    Publication date: January 15, 2015
    Inventor: Doo Jin Byun
  • Patent number: 8912002
    Abstract: Provided is a method for high concentration cation exchange metathesis of divalent ions such as calcium with univalent ions such as sodium or potassium. Due to the difference between ionic valences between the exchanged ions, the provided process behavior is strongly dependent upon the selection of resin properties and to total solution normality. A combination of resin properties and solution normality is provided to achieve the cation exchange.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: December 16, 2014
    Assignee: Cyanco Holding Corporation
    Inventors: Marcus Rajchel, Michael F. Ray
  • Patent number: 8912001
    Abstract: Provided is a method for high concentration cation exchange metathesis of divalent ions such as calcium with univalent ions such as sodium or potassium. Due to the difference between ionic valences between the exchanged ions, the provided process behavior is strongly dependent upon the selection of resin properties and to total solution normality. A combination of resin properties and solution normality is provided to achieve the cation exchange.
    Type: Grant
    Filed: April 12, 2011
    Date of Patent: December 16, 2014
    Assignee: Cyanco Holding Corporation
    Inventors: Marcus Rajchel, Michael F. Ray
  • Publication number: 20140349407
    Abstract: The present invention provides a method of deterioration analysis that enables detailed analysis of the deterioration, especially of the surface, of a polymer material containing at least two diene polymers. The present invention relates to a method of deterioration analysis including: irradiating a polymer material containing at least two diene polymers with high intensity x-rays; and measuring x-ray absorption while varying the energy of the x-rays, to analyze the deterioration of each diene polymer.
    Type: Application
    Filed: November 2, 2012
    Publication date: November 27, 2014
    Inventors: Fusae Kaneko, Hiroyuki Kishimoto
  • Patent number: 8834954
    Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: September 16, 2014
    Assignee: SIO2 Medical Products, Inc.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Publication number: 20140242623
    Abstract: We disclose methods and compositions for preparation of stimuli-responsive plastics that are capable of responding to chemical and/or physical signals in their environment. In one embodiment the plastics consist of patterned mixtures of poly(phthalaldehyde) polymers in which each polymer contains a different end-capping group (also called a “trigger”), responsive to a different signal. Other embodiments use different polymers and different triggers. The plastics may be homogeneous in composition, but each polymer within the plastic is capable of responding to a different signal and depolymerizing once this signal reacts with the trigger. This process of depolymerization enables the plastic to alter its physical features non-linearly to external signals: i.e., the degree of change in physical form is much larger than the intensity of the initial signal.
    Type: Application
    Filed: May 10, 2011
    Publication date: August 28, 2014
    Inventors: Scott T. Phillips, Wanji Seo, Jessica Robbins, Michael Olah, Kyle Schmid, Anthony Michael DiLauro
  • Patent number: 8796033
    Abstract: A method for analyzing a minute quantity of a material included in a different material is performed in short extraction treatment without taking a long time and the minute content is rapidly analyzed. The method of analyzing a minute content includes mounting on a sample table a sample piece of a material having a minute content of a different material to be analyzed; dropping onto the sample table a solvent for extracting the minute content from the sample piece, so that the solvent is disposed between the sample table and the sample piece; maintaining at room temperature the solvent between the sample table and the sample piece, and, with the solvent maintained between the sample table and the sample piece, extracting the material of the minute content from the sample piece; and analyzing the content extracted from the sample piece.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: August 5, 2014
    Assignee: Mitsubishi Denki Kabushiki Kaisha
    Inventors: Jiro Naka, Hiroshi Kurokawa, Junji Kobayashi, Satoru Toyama, Noriko Hirano, Eiji Hara
  • Patent number: 8722416
    Abstract: An analytical method comprising performing a first fractionation of a polymer sample based on differences in crystallizability to provide a first set of sample fractions, performing a first analysis on the first set of sample fractions, performing a second fractionation of the first set of sample fractions to produce a second set of sample fractions, performing a second analysis on the second set of sample fractions, and synchronizing the first fractionation and second fractionation to provide about concurrent analysis of the polymer sample.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: May 13, 2014
    Assignee: Chevron Phillips Chemical Company LP
    Inventors: Youlu Yu, Chung C. Tso, Paul J. DesLauriers
  • Publication number: 20140099723
    Abstract: The present invention provides a deterioration analysis method capable of analyzing in detail deterioration of a polymer material, and in particular deterioration in the surface condition of a polymer material with low conductivity. The present invention relates to a deterioration analysis method including irradiating a polymer material with a metal coating having a thickness of 100 ? or less formed thereon, with high intensity X-rays, and measuring X-ray absorption while varying the energy of the X-rays, to analyze deterioration of the polymer.
    Type: Application
    Filed: October 4, 2013
    Publication date: April 10, 2014
    Applicant: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventors: Fusae KANEKO, Hiroyuki KISHIMOTO
  • Patent number: 8679850
    Abstract: The present invention concerns a method of detecting cationic polymers comprising: obtaining a target water sample containing a cationic polymer; adding a polymer dispersant solution and a phosphate solution to the target water sample, the polymer dispersant solution is comprised of a polymer dispersant with calcium and magnesium hardness and the phosphate solution is comprised of a phosphate; standing the target water sample; and measuring the turbidity of the target water sample; comparing the turbidity of said target water sample with a calibration curve of the turbidity of samples containing known concentrations of cationic polymers to determine the concentration of cationic polymers in said target water sample.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: March 25, 2014
    Assignee: General Electric Company
    Inventors: Guixi Zhang, Sijing Wang, Hong Xu, Xiaofeng Tang
  • Patent number: 8669113
    Abstract: The present invention relates to methods, monitors and systems measuring lysophosphatidylcholine, its derivatives and/or procalcitonin as well as at least one clinical marker (e.g. temperature or respiration rate) and/or at least one biomarker for the early detection of sepsis in a subject.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: March 11, 2014
    Assignee: Becton, Dickinson and Company
    Inventors: Song Shi, Richard L. Moore, James Garrett
  • Patent number: 8618226
    Abstract: A method for determining the styrene microblock content of a copolymer sample, the method comprising: (i) pyrolyzing the copolymer sample to form polymer fragments of the polymer sample; (ii) analyzing the fragments to determine the relative amounts of styrene monomer fragments, styrene dimer fragments, and styrene trimer fragments, where the relative amounts of the fragments include the amount of any given fragment relative to the total of the monomer fragments, dimer fragments, and trimer fragments; and (iii) using the relative amounts of the styrene monomer fragments, styrene dimer fragments, and styrene trimer fragments to predict the polystyrene microblock content from a mathematical model that is based upon the relative styrene monomer fragments, relative styrene dimer fragments, relative styrene trimer fragments, and microblock content of a copolymer having known microblock content.
    Type: Grant
    Filed: May 21, 2012
    Date of Patent: December 31, 2013
    Assignee: Bridgestone Corporation
    Inventors: Waruna Chethiya Bandara Kiridena, Mindaugas Rackaitis, Terrence Eugene Hogan, Dennis R. Brumbaugh, William L. Hergenrother
  • Publication number: 20130260469
    Abstract: The present invention is seen to provide a new methodology, testing system designs and concept to enable in situ real time monitoring of the cure process. Apparatus, system, and method for the non-destructive, in situ monitoring of the time dependent curing of advanced materials using one or more differential ultrasonic waveguide cure monitoring probes. A differential ultrasonic waveguide cure monitoring probe in direct contact with the material to be cured and providing in situ monitoring of the cure process to enable assessment of the degree of cure or cure level in a non-cure related signal variances (e.g., temperature) independent calibrated response manner. A differential ultrasonic waveguide cure monitoring probe including a transducer coupled to a waveguide and incorporating correction and calibration methodology to accurately and reproducibly monitor the cure process and enable assessment of cure level via ultrasonic reflection measurements.
    Type: Application
    Filed: September 20, 2012
    Publication date: October 3, 2013
    Applicant: Materials And Sensors Technologies, Inc.
    Inventors: Borislav B. DJORDJEVIC, Lawrence L. Rouch
  • Patent number: 8512796
    Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed, for example using material outgassed from a surface to inspect the properties of a surface coating.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: August 20, 2013
    Assignee: Si02 Medical Products, Inc.
    Inventors: John T. Felts, Thomas E. Fisk, Robert S. Abrams, John Ferguson, Jonathan R. Freedman, Robert J. Pangborn, Peter J. Sagona
  • Patent number: 8486705
    Abstract: The invention provides methods and apparatus for characterizing complex polymeric mixture of interest. Candidate solutions are eliminated from a solution space using one or more experimental measurements of a polymeric mixture of interest. The elimination step can be repeated one or more times using different experimental measurements produced by various chemical and physical protocols, so that the remaining candidate solutions converge to describe the actual polymeric mixture under investigation. Once the composition of the complex polymeric mixture has been characterized, the information thus generated can be used to facilitate, for example, the manufacture of a bio-equivalent of the complex polymeric mixture.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: July 16, 2013
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventor: Sasisekharan Raguram
  • Patent number: 8476076
    Abstract: A method and apparatus for chromatography of a polyolefin polymer by flowing a solution of the polyolefin polymer through liquid flowing through a graphitic carbon liquid chromatography stationary phase. The method can be used to determine the monomer to comonomer ratio of a polyolefin copolymer such as a copolymer of ethylene and 1-octene or a copolymer of propylene and ethylene.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: July 2, 2013
    Assignee: Dow Global Technologies LLC
    Inventors: Freddy A. Van Damme, John W. Lyons, William L. Winniford, Alexander Willem deGroot, Matthew D. Miller
  • Patent number: 8455265
    Abstract: A surface grafted conjugated polyelectrolyte (CPE) is formed by coupling a CPE by a coupling moiety to the surface of a substrate. The substrate can be of any shape and size, and for many uses of the surface grafted CPE, it is advantageous that the substrate is a nanoparticle or microparticle. Surface grafted CPEs are presented that use silica particles as the substrate, where a modified silane coupling agent connects the surface to the CPE by a series of covalent bonds. Two methods of preparing the surface grafted CPEs are presented. One method involves the inclusion of the surface being modified by the coupling agent and condensed with monomers that form the CPE in a grafted state to the substrate. A second method involves the formation of a CPE with terminal groups that are complimentary to functionality that has been placed on the surface of the substrate by reaction with a coupling agent. The surface grafted CPEs are also described for use as biosensors and biocides.
    Type: Grant
    Filed: February 29, 2008
    Date of Patent: June 4, 2013
    Assignee: STC.UNM
    Inventors: David G. Whitten, Sireesha Chemburu, Thomas Corbitt, Linnea Ista, Gabriel Lopez, Kirk S. Schanze, Motokatsu Ogawa, Eunkyung Ji
  • Publication number: 20130122597
    Abstract: A multi-purpose reagent composition is used for simultaneously determining concentrations of at least two analytes in a water sample. The two analytes are selected from the group consisting of free chlorine, pH, anionic polymer, and phosphates. In one embodiment, the multi-purpose reagent composition is for simultaneously determining the concentration of free chlorine and pH and comprises a free chlorine sensitive dye and pH indicator. In another embodiment, the reagent composition is for simultaneously determining of free chlorine and anionic polymer and includes a free chlorine sensitive dye, a pH buffer, cationic dye, and organic co-solvent. Thus, the pairs of free chlorine and pH or free chlorine and anionic polymer are determined using a single reagent composition. The reagent composition can also be the main reagent for one analyte analysis when it is used alone and also function as an ancillary reagent when it is combined with a second reagent composition for the determination of another analyte.
    Type: Application
    Filed: August 3, 2010
    Publication date: May 16, 2013
    Inventors: Caibin Xiao, Bingzhi Chen, Chunbo Yu, Hong Xu
  • Patent number: 8420759
    Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has ?13C value of greater than ?22‰.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: April 16, 2013
    Assignees: The Goodyear Tire & Rubber Company, Danisco US, Inc.
    Inventors: Frank J. Feher, Gregory M. Whited, Gopal K. Chotani, Fernando Valle, Carol Fioresi, Karl J. Sanford, Joseph C. McAuliffe, Marguerite Cervin, Aaron S. Puhala, Andrei Miasnikov, Ilana S. Aldor
  • Patent number: 8394638
    Abstract: A system may include a means for administering a therapeutic agent to a subject; a means for administering a first pharmaceutically-acceptable taggant to the subject at least substantially concurrent with the therapeutic agent, the first pharmaceutically-acceptable taggant having a pharmacokinetic profile; and a means for administering a second pharmaceutically-acceptable taggant to the subject with the first pharmaceutically-acceptable taggant, the second pharmaceutically-acceptable taggant having a pharmacokinetic profile different from the pharmacokinetic profile of the first pharmaceutically-acceptable taggant.
    Type: Grant
    Filed: November 10, 2008
    Date of Patent: March 12, 2013
    Assignee: The Invention Science Fund I, LLC
    Inventors: Roderick A. Hyde, Muriel Y. Ishikawa, Jordin T. Kare, Eric C. Leuthardt, Dennis J. Rivet, Lowell L. Wood, Jr., Victoria Y. H. Wood
  • Publication number: 20130040394
    Abstract: Provided is a method for high concentration cation exchange metathesis of divalent ions such as calcium with univalent ions such as sodium or potassium. Due to the difference between ionic valences between the exchanged ions, the provided process behavior is strongly dependent upon the selection of resin properties and to total solution normality. A combination of resin properties and solution normality is provided to achieve the cation exchange.
    Type: Application
    Filed: October 12, 2012
    Publication date: February 14, 2013
    Applicant: Cyanco Holding Corporation
    Inventor: Cyanco Holding Corporation
  • Patent number: 8357536
    Abstract: In an embodiment, there is disclosed an inspection method for detecting the presence of imprintable medium on an imprint lithography template. The method includes contacting the imprint lithography template with a marker, the marker being attachable to imprintable medium that may be on the imprint lithography template, the marker being configured to interact with incident radiation when attached to the imprintable medium, directing radiation at the imprint lithography template, and measuring radiation re-directed by the imprint lithography template to attempt to detect presence of a marker that has attached to the imprintable medium, from the interaction of the marker with the incident radiation, and thus detect the presence of imprintable medium to which the marker is attached.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: January 22, 2013
    Assignee: ASML Netherlands B.V.
    Inventor: Sander Frederik Wuister
  • Publication number: 20120296054
    Abstract: A method for determining the styrene microblock content of a copolymer sample, the method comprising: (i) pyrolyzing the copolymer sample to form polymer fragments of the polymer sample; (ii) analyzing the fragments to determine the relative amounts of styrene monomer fragments, styrene dimer fragments, and styrene trimer fragments, where the relative amounts of the fragments include the amount of any given fragment relative to the total of the monomer fragments, dimer fragments, and trimer fragments; and (iii) using the relative amounts of the styrene monomer fragments, styrene dimer fragments, and styrene trimer fragments to predict the polystyrene microblock content from a mathematical model that is based upon the relative styrene monomer fragments, relative styrene dimer fragments, relative styrene trimer fragments, and microblock content of a copolymer having known microblock content.
    Type: Application
    Filed: May 21, 2012
    Publication date: November 22, 2012
    Inventors: Waruna Chethiya Bandara Kiridena, Mindaugas Rackaitis, Terrence Eugene Hogan, Dennis R. Brumbaugh, William L. Hergenrother
  • Publication number: 20120270328
    Abstract: The present invention concerns a method of detecting cationic polymers comprising: obtaining a target water sample containing a cationic polymer; adding a polymer dispersant solution and a phosphate solution to the target water sample, the polymer dispersant solution is comprised of a polymer dispersant with calcium and magnesium hardness and the phosphate solution is comprised of a phosphate; standing the target water sample; and measuring the turbidity of the target water sample; comparing the turbidity of said target water sample with a calibration curve of the turbidity of samples containing known concentrations of cationic polymers to determine the concentration of cationic polymers in said target water sample.
    Type: Application
    Filed: December 21, 2010
    Publication date: October 25, 2012
    Applicant: General Electric Company
    Inventors: Guixi Zhang, Sijing Wang, Hong Xu, Xiaofeng Tang
  • Patent number: 8222039
    Abstract: A process for purification of water soluble polymers is provided. A polymer of interest can be separated from a mixture of polymers, provided the polymer of interest differs from other polymers in the mixture in the number of reactive terminal groups. The process involves derivatizing polymers at the reactive terminal groups with a derivatizing molecule, bearing either (i) two or three cationic or anionic ionizable groups, and a group capable of covalent bonding to the reactive terminal groups or (ii) three or four ionizable groups, at least one of which is capable of covalent bonding to the reactive terminal groups; followed by ion exchange. The process allows removal of PEG from MPEG, and can be used for polymers having an average size greater than 9,000 Da Derivatization may be reversible in order to allow re-use of recovered contaminant polymers.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: July 17, 2012
    Assignee: Biovectra Inc.
    Inventors: James F. Monthony, Li Yang, Kurt E. Kershaw, Christopher D. Winslow, John G. Riley
  • Patent number: 8206993
    Abstract: The diffusion coefficients and relaxation times of mixtures of alkanes follow simple scaling laws based on the chain length of the constituents and the mean chain length of the mixture. These scaling laws are used to determine chain sizes in a mixture from the distribution of the diffusion coefficients. These scaling laws can be used to determine the mean chain lengths (or chain lengths) of a sample (alkanes or mixtures of alkanes) and therefore the constituents of the sample.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: June 26, 2012
    Assignee: Schlumberger Technology Corporation
    Inventor: Denise Freed
  • Patent number: 8183050
    Abstract: The present invention provides methods and compositions useful for the diagnosis or prognosis of a systemic inflammatory condition such as sepsis.
    Type: Grant
    Filed: September 28, 2006
    Date of Patent: May 22, 2012
    Assignee: Becton, Dickinson and Company
    Inventors: Song Shi, Thomas Gentle, Richard Moore
  • Patent number: 8178353
    Abstract: In one aspect, the invention is directed to a method for determining the concentration of anionic polymers or oligomers in industrial water comprising combining a buffer solution and a cationic dye solution, measuring absorbance of the buffer-dye admixture at selected wavelength(s) and determining the polymer or oligomer concentration from the previously determined absorbance values. In alternate embodiments of the invention, the buffer solution may be a multifunctional buffer solution and may be comprised of multiple buffers, masking agents. and/or stabilizing agents and combinations thereof. Other embodiments provide that multiple dyes may be employed.
    Type: Grant
    Filed: May 31, 2007
    Date of Patent: May 15, 2012
    Assignee: General Electric Company
    Inventors: Caibin Xiao, Yangang Liang, Li Zhang
  • Patent number: 8158436
    Abstract: The invention provides methods and apparatus for characterizing complex polymeric mixture of interest. Candidate solutions are eliminated from a solution space using one or more experimental measurements of a polymeric mixture of interest. The elimination step can be repeated one or more times using different experimental measurements produced by various chemical and physical protocols, so that the remaining candidate solutions converge to describe the actual polymeric mixture under investigation. Once the composition of the complex polymeric mixture has been characterized, the information thus generated can be used to facilitate, for example, the manufacture of a bio-equivalent of the complex polymeric mixture.
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: April 17, 2012
    Assignee: Momenta Pharmaceuticals, Inc.
    Inventor: Sasisekharan Raguram
  • Patent number: 8110371
    Abstract: The present invention provides methods for identifying whether or not a patient has, or is at risk of developing drug induced organ damage and methods of treating patients having drug induced organ damage. In particular, the invention relates to a method for identifying whether or not a patent has, or is at risk of developing paracetamol induced liver damage.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: February 7, 2012
    Assignee: The University Court of the University of Edinburgh
    Inventors: James Dear, David John Webb
  • Patent number: 8084214
    Abstract: The present invention intends to provide a high sensitivity method for identifying the type of a protein contained in each cell with a diameter of ten to several tens ?m and a sample treatment solution required for it. The above is achieved by three steps of (1) treating a slice of a diseased tissue with an aqueous solution containing gold particles and a digestive enzyme, and digesting restrictively a protein of interest, (2) measuring a 2-dimensional distribution of fragmented peptides by TOF-SIMS, and (3) visualizing a 2-dimensional distribution of the target protein in the slice of the diseased tissue using the results of the proteome analysis and by means of a numerical analysis.
    Type: Grant
    Filed: April 7, 2008
    Date of Patent: December 27, 2011
    Assignee: Canon Kabushiki Kaisha
    Inventors: Hiroyuki Hashimoto, Manabu Komatsu, Satoru Hatakeyama
  • Publication number: 20110312098
    Abstract: The present invention is directed to methods for assessing the purity of carbon nanotube (CNT) compositions, specifically, a method for assessing the presence of contaminants in a CNT composition using polyaryl ethynyl (PAE) conjugate polymer as an indicator material. Additionally, compositions and kits comprising a polyaryl ethynyl (PAE) conjugate polymer are also provided.
    Type: Application
    Filed: May 19, 2011
    Publication date: December 22, 2011
    Applicant: ZYVEX PERFORMANCE MATERIALS
    Inventors: Weijun Wang, Srinagesh K. Potluri, Yongfeng Wang, Iti Srivastava
  • Publication number: 20110306142
    Abstract: Devices and methods for immobilizing micrometer sized liquid domains onto a chemically functionalized substrate surface are disclosed. A multifunctional polymer is adsorbed at the surface interface of the liquid microdomains, and the liquid microdomains are immobilized by covalent bonding or non-covalent forces such as electrostatic attraction between the adsorbed multifunctional polymer and the functionalized substrate surface.
    Type: Application
    Filed: April 15, 2011
    Publication date: December 15, 2011
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: David M. Lynn, Nicholas L. Abbott, Maren E. Buck, Michael I. Kinsinger
  • Patent number: 8076147
    Abstract: A method and apparatus for chromatography of a polyolefin polymer by flowing a solution of the polyolefin polymer through liquid flowing through a graphitic carbon liquid chromatography stationary phase. The method can be used to determine the monomer to comonomer ratio of a polyolefin copolymer such as a copolymer of ethylene and 1-octene or a copolymer of propylene and ethylene.
    Type: Grant
    Filed: October 2, 2009
    Date of Patent: December 13, 2011
    Assignee: Dow Global Technologies LLC
    Inventors: Freddy Van Damme, John W. Lyons, William L. Winniford, Alexander W. Degroot, Matthew D. Miller
  • Patent number: 8076146
    Abstract: A method for evaluating rubber is provided which can evaluate the degree of crosslinking of a crosslinked rubber product within a short period of time without performing any specific treatment. In the above method, the amount of energy shift of the peak (such as the peak of C12p3/2 of chlorinated butyl rubber) of a constituent element of the rubber is measured by photoelectron spectroscopy, and the degree of crosslinking of the rubber is evaluated from the amount of energy shift. In addition, a method for manufacturing a rubber product is also provided which includes the steps of measuring the amount of energy shift of the peak of a constituent element of the rubber product by a photoelectron spectrometer which is installed in a manufacturing line and then feeding back measurement result to adjust heat molding conditions so as to obtain a desired degree of crosslinking.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: December 13, 2011
    Assignee: Canon Kabushiki Kaisha
    Inventor: Akemi Ishizaki
  • Patent number: 8048679
    Abstract: The present invention provides several methods of determining values of physical or chemical properties of polymers. In these methods, at least two polymer training samples are provided. Characteristics of the polymer microstructures of the training samples are correlated with values of physical or chemical properties of the training samples. These correlations are subsequently applied to the respective characteristics of polymer test samples in order to determine the values of physical or chemical properties of the test samples.
    Type: Grant
    Filed: August 25, 2010
    Date of Patent: November 1, 2011
    Assignee: Chevron Phillips Chemical Company, LP
    Inventors: Paul J. DesLauriers, David C. Rohlfing