Abstract: This invention relates to mono cyclopentadienyl pyridyl hydroxyl amine catalyst compounds represented by Formula I(a) or I(b): wherein: M is a group 3-12 metal; R1 is a hydrocarbyl group or a silyl group; R2, R3, R4, R5, R6, R7, R8, R9, and R10 are independently selected from the group consisting of hydrogen, hydrocarbyl, alkoxy, silyl, amino, aryloxy, halogen and phosphino, wherein any two adjacent R groups may be joined to form a saturated or unsaturated single or multicyclic hydrocarbyl ring or heterocyclic ring; and each X1 and X2 is independently an anionic leaving group or X1 and X2 may be joined together to form a dianionic group.

Abstract: The present disclosure provides pyridyl hydroxyl amine catalyst compounds and systems containing the compounds. The present disclosure is also directed to polymerization processes to produce polyolefin polymers from catalyst systems including one or more olefin polymerization catalysts, at least one activator, and an optional support.

Abstract: The present disclosure provides catalyst compounds represented by Formula (I): where Q is OR13, SR13, NR13R14, PR13R14, or a heterocyclic ring; each R1-14 is independently hydrogen, C1-C40 hydrocarbyl, substituted C1-C40 hydrocarbyl, a heteroatom, or a heteroatom-containing group, or multiple R1-14 are joined together to form a C4-C62 cyclic, heterocyclic, or polycyclic ring structure, or combination(s) thereof; each X1 and X2 is independently C1-C20 hydrocarbyl, substituted C1-C20 hydrocarbyl, a heteroatom, or a heteroatom-containing group, or X1 and X2 join together to form a C4-C62 cyclic, heterocyclic, or polycyclic ring structure; and Y is a hydrocarbyl. The present disclosure also provides catalyst systems including an activator, a support, and a catalyst of the present disclosure. The present disclosure also provides polymerization processes including introducing olefin monomers to a catalyst system.

Abstract: A composition and method for the photometric determination of a film-forming amine in liquid by adding an indicator reagent to an aqueous system that is pH dependent, combining a water soluble non-ionic polymer to modify the physical properties of the aqueous system, and adding an acidic buffer to said aqueous system to lower pH and activate said indicator, said water soluble polymer keeping the filming amine/indicator complex in solution despite the acidic buffer and preventing it from precipitating out.

Abstract: Systems for quantifying one or more target analyte concentrations in a process solution are provided and can be used, for example, in methods for quantifying a target analyte concentration. These systems and methods include continuous and batchwise automated titration methods that use titration chemistries to measure the target analyte concentration in the process solution using a multiwavelength detector. The methods provide for efficient and robust automated titration methods for a variety of target analytes and can include methods that analyze more than one analyte and that provide for a dynamic range for measurement of more than one target analyte concentration.

Abstract: The present disclosure provides catalyst compounds including a nonsymmetric bridged amine bis(phenolate), catalyst systems including such, and uses thereof. Catalyst compounds, catalyst systems, and processes of the present disclosure can provide high comonomer content and high molecular weight polymers having narrow Mw/Mn values, contributing to good processability for the polymer itself and for the polymer used in a composition.

Abstract: An apparatus and a method to withdraw samples from a polymerization plant using a defined sequence of steps combined with locking devices for valves opened by a single key.

Abstract: Disclosed is a curable sealant composition including: (i) a thiol-terminated prepolymer and/or monomers thereof, wherein the thiol-terminated prepolymer is a polythioether or a polysulfide; (ii) an “ene” crosslinker having a molecular weight of about 100 to about 5000; and (iii) a pH indicator molecule including a quantum dot functionalized with a pH-responsive ligand. Methods for determining a sufficient cure state of a composition by combining the thiol-terminated prepolymer and/or monomers thereof and the “ene” crosslinker with a pH indicator molecule, including a quantum dot functionalized with a pH-responsive ligand, and (ii) then subjecting a resultant mixture of (i) to curing conditions until the mixture changes its color are also disclosed.

Abstract: This invention provides slippery liquid-infused porous surfaces (SLIPS) using nanoporous or microporous and chemically reactive polymer multilayers. This approach permits fabrication of slippery anti-fouling coatings on complex surfaces and provides new means to manipulate the mobilities of contacting aqueous fluids. The results expand the range of tools that can be used to manipulate the behaviors of SLIPS and open the door to new applications of this emerging class of soft materials.

Abstract: The present invention provides a method of deterioration analysis that enables detailed analysis of the deterioration, especially of the surface, of a polymer material containing at least two diene polymers. The present invention relates to a method of deterioration analysis including: irradiating a polymer material containing at least two diene polymers with high intensity x-rays; and measuring x-ray absorption while varying the energy of the x-rays, to analyze the deterioration of each diene polymer.

Abstract: A substrate having a pattern of two or more materials exhibiting different grafting efficiencies for a temperature-responsive polymer that varies its interaction with water in a temperature range of 0 to 80° C. by electron beam irradiation under the same conditions is grafted with the temperature-responsive polymer by simultaneously irradiating the surfaces of the materials with electron beams to obtain a temperature-responsive cell culture substrate. According to this method, a temperature-responsive cell culture substrate having a surface (1) that allows cells to adhere thereto and to grow thereon during cell culturing and that allows the adhering and grown cells to be detached therefrom by changing the culturing temperature and a surface (2) that does not allow the cells to adhere thereto at all can be obtained by a simple process.

Abstract: Provided is a method of evaluating a resin capable of quantitatively evaluating a deterioration degree of the resin with high accuracy and ease. The method includes evaluating the resin based on a shift of a characteristic peak representing a deterioration degree of the resin, the peak being observed in thermal analysis of the resin by a temperature increase, to lower temperatures.

Abstract: Provided is a method for producing synthetic amylospheroids efficiently, the method including agitating a liquid containing amyloid ?-peptides in the presence of a plasticizer. Amylospheroid refers to an assembly of amyloid ?-peptides that selectively can induce cell death of functionally mature neurons. Amylospheroid is considered to play a central role in the development of Alzheimer's disease and dementia with Lewy bodies.

Abstract: The present invention provides materials, devices, and methods related to determination of an analyte. In some embodiments, an analyte may be determined by monitoring, for example, a change in an optical signal of a luminescent material (e.g., particle) upon exposure to an analyte. The present invention may be particularly advantageous in that some embodiments may comprise an emissive species useful as an internal reference standard. Methods of the invention may also be useful in the quantitative determination of an analyte. In some cases, the present invention may allow for selective determination of an analyte.

Abstract: The present invention relates to an apparatus for quantifying the binding and dissociation kinetics of molecular interactions of small molecular bio materials with high sensitivity almost without the influence of a change in the reflective index resulting from a buffer solution by making polarized incident light incident on the binding layer of a bio material, formed in a thin dielectric film, so that the polarized incident light satisfies a p-wave non-reflecting condition and a quantifying method using the same.

Abstract: Disclosed is a test apparatus of accelerated photo-degradation measuring a degradation caused by photo-degradation in a material or a product by light containing UV light and visible light that simulate the solar light-inducing degradation. The apparatus includes a light irradiating unit configured to irradiate light using at least one electrodeless plasma lamp; a light condensing unit configured to collect light emitted from the light irradiating unit and irradiate the light uniformly into the surface of the specimen for the material or the product; and a specimen holder configured to fix the specimen, and the specimen holder being fixed at a predetermined position or rotated. Further, the at least one electrodeless plasma lamp generates light having a light power spectrum similar to a solar light in a region of UV light and short-wavelength visible light corresponding to a range of about 300-500 nm.

Abstract: Provided is a method for high concentration cation exchange metathesis of divalent ions such as calcium with univalent ions such as sodium or potassium. Due to the difference between ionic valences between the exchanged ions, the provided process behavior is strongly dependent upon the selection of resin properties and to total solution normality. A combination of resin properties and solution normality is provided to achieve the cation exchange.

Abstract: Provided is a method for high concentration cation exchange metathesis of divalent ions such as calcium with univalent ions such as sodium or potassium. Due to the difference between ionic valences between the exchanged ions, the provided process behavior is strongly dependent upon the selection of resin properties and to total solution normality. A combination of resin properties and solution normality is provided to achieve the cation exchange.

Abstract: The present invention provides a method of deterioration analysis that enables detailed analysis of the deterioration, especially of the surface, of a polymer material containing at least two diene polymers. The present invention relates to a method of deterioration analysis including: irradiating a polymer material containing at least two diene polymers with high intensity x-rays; and measuring x-ray absorption while varying the energy of the x-rays, to analyze the deterioration of each diene polymer.

Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed.

Abstract: We disclose methods and compositions for preparation of stimuli-responsive plastics that are capable of responding to chemical and/or physical signals in their environment. In one embodiment the plastics consist of patterned mixtures of poly(phthalaldehyde) polymers in which each polymer contains a different end-capping group (also called a “trigger”), responsive to a different signal. Other embodiments use different polymers and different triggers. The plastics may be homogeneous in composition, but each polymer within the plastic is capable of responding to a different signal and depolymerizing once this signal reacts with the trigger. This process of depolymerization enables the plastic to alter its physical features non-linearly to external signals: i.e., the degree of change in physical form is much larger than the intensity of the initial signal.

Abstract: A method for analyzing a minute quantity of a material included in a different material is performed in short extraction treatment without taking a long time and the minute content is rapidly analyzed. The method of analyzing a minute content includes mounting on a sample table a sample piece of a material having a minute content of a different material to be analyzed; dropping onto the sample table a solvent for extracting the minute content from the sample piece, so that the solvent is disposed between the sample table and the sample piece; maintaining at room temperature the solvent between the sample table and the sample piece, and, with the solvent maintained between the sample table and the sample piece, extracting the material of the minute content from the sample piece; and analyzing the content extracted from the sample piece.

Abstract: An analytical method comprising performing a first fractionation of a polymer sample based on differences in crystallizability to provide a first set of sample fractions, performing a first analysis on the first set of sample fractions, performing a second fractionation of the first set of sample fractions to produce a second set of sample fractions, performing a second analysis on the second set of sample fractions, and synchronizing the first fractionation and second fractionation to provide about concurrent analysis of the polymer sample.

Abstract: The present invention provides a deterioration analysis method capable of analyzing in detail deterioration of a polymer material, and in particular deterioration in the surface condition of a polymer material with low conductivity. The present invention relates to a deterioration analysis method including irradiating a polymer material with a metal coating having a thickness of 100 ? or less formed thereon, with high intensity X-rays, and measuring X-ray absorption while varying the energy of the X-rays, to analyze deterioration of the polymer.

Abstract: The present invention concerns a method of detecting cationic polymers comprising: obtaining a target water sample containing a cationic polymer; adding a polymer dispersant solution and a phosphate solution to the target water sample, the polymer dispersant solution is comprised of a polymer dispersant with calcium and magnesium hardness and the phosphate solution is comprised of a phosphate; standing the target water sample; and measuring the turbidity of the target water sample; comparing the turbidity of said target water sample with a calibration curve of the turbidity of samples containing known concentrations of cationic polymers to determine the concentration of cationic polymers in said target water sample.

Abstract: The present invention relates to methods, monitors and systems measuring lysophosphatidylcholine, its derivatives and/or procalcitonin as well as at least one clinical marker (e.g. temperature or respiration rate) and/or at least one biomarker for the early detection of sepsis in a subject.

Abstract: A method for determining the styrene microblock content of a copolymer sample, the method comprising: (i) pyrolyzing the copolymer sample to form polymer fragments of the polymer sample; (ii) analyzing the fragments to determine the relative amounts of styrene monomer fragments, styrene dimer fragments, and styrene trimer fragments, where the relative amounts of the fragments include the amount of any given fragment relative to the total of the monomer fragments, dimer fragments, and trimer fragments; and (iii) using the relative amounts of the styrene monomer fragments, styrene dimer fragments, and styrene trimer fragments to predict the polystyrene microblock content from a mathematical model that is based upon the relative styrene monomer fragments, relative styrene dimer fragments, relative styrene trimer fragments, and microblock content of a copolymer having known microblock content.

Abstract: The present invention is seen to provide a new methodology, testing system designs and concept to enable in situ real time monitoring of the cure process. Apparatus, system, and method for the non-destructive, in situ monitoring of the time dependent curing of advanced materials using one or more differential ultrasonic waveguide cure monitoring probes. A differential ultrasonic waveguide cure monitoring probe in direct contact with the material to be cured and providing in situ monitoring of the cure process to enable assessment of the degree of cure or cure level in a non-cure related signal variances (e.g., temperature) independent calibrated response manner. A differential ultrasonic waveguide cure monitoring probe including a transducer coupled to a waveguide and incorporating correction and calibration methodology to accurately and reproducibly monitor the cure process and enable assessment of cure level via ultrasonic reflection measurements.

Abstract: Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed, for example using material outgassed from a surface to inspect the properties of a surface coating.

Abstract: The invention provides methods and apparatus for characterizing complex polymeric mixture of interest. Candidate solutions are eliminated from a solution space using one or more experimental measurements of a polymeric mixture of interest. The elimination step can be repeated one or more times using different experimental measurements produced by various chemical and physical protocols, so that the remaining candidate solutions converge to describe the actual polymeric mixture under investigation. Once the composition of the complex polymeric mixture has been characterized, the information thus generated can be used to facilitate, for example, the manufacture of a bio-equivalent of the complex polymeric mixture.

Abstract: A method and apparatus for chromatography of a polyolefin polymer by flowing a solution of the polyolefin polymer through liquid flowing through a graphitic carbon liquid chromatography stationary phase. The method can be used to determine the monomer to comonomer ratio of a polyolefin copolymer such as a copolymer of ethylene and 1-octene or a copolymer of propylene and ethylene.

Abstract: A surface grafted conjugated polyelectrolyte (CPE) is formed by coupling a CPE by a coupling moiety to the surface of a substrate. The substrate can be of any shape and size, and for many uses of the surface grafted CPE, it is advantageous that the substrate is a nanoparticle or microparticle. Surface grafted CPEs are presented that use silica particles as the substrate, where a modified silane coupling agent connects the surface to the CPE by a series of covalent bonds. Two methods of preparing the surface grafted CPEs are presented. One method involves the inclusion of the surface being modified by the coupling agent and condensed with monomers that form the CPE in a grafted state to the substrate. A second method involves the formation of a CPE with terminal groups that are complimentary to functionality that has been placed on the surface of the substrate by reaction with a coupling agent. The surface grafted CPEs are also described for use as biosensors and biocides.

Abstract: A multi-purpose reagent composition is used for simultaneously determining concentrations of at least two analytes in a water sample. The two analytes are selected from the group consisting of free chlorine, pH, anionic polymer, and phosphates. In one embodiment, the multi-purpose reagent composition is for simultaneously determining the concentration of free chlorine and pH and comprises a free chlorine sensitive dye and pH indicator. In another embodiment, the reagent composition is for simultaneously determining of free chlorine and anionic polymer and includes a free chlorine sensitive dye, a pH buffer, cationic dye, and organic co-solvent. Thus, the pairs of free chlorine and pH or free chlorine and anionic polymer are determined using a single reagent composition. The reagent composition can also be the main reagent for one analyte analysis when it is used alone and also function as an ancillary reagent when it is combined with a second reagent composition for the determination of another analyte.

Abstract: It has been found that certain cells in culture can convert more than about 0.002 percent of the carbon available in the cell culture medium into isoprene. These cells have a heterologous nucleic acid that (i) encodes an isoprene synthase polypeptide and (ii) is operably linked to a promoter. The isoprene produced in such a cultured medium can then be recovered and polymerized into synthetic rubbers and other useful polymeric materials. The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being derived from non-petrochemical based resources. They can also be analytically distinguished from rubbers that come from natural sources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has ?13C value of greater than ?22‰.

Abstract: A system may include a means for administering a therapeutic agent to a subject; a means for administering a first pharmaceutically-acceptable taggant to the subject at least substantially concurrent with the therapeutic agent, the first pharmaceutically-acceptable taggant having a pharmacokinetic profile; and a means for administering a second pharmaceutically-acceptable taggant to the subject with the first pharmaceutically-acceptable taggant, the second pharmaceutically-acceptable taggant having a pharmacokinetic profile different from the pharmacokinetic profile of the first pharmaceutically-acceptable taggant.

Abstract: Provided is a method for high concentration cation exchange metathesis of divalent ions such as calcium with univalent ions such as sodium or potassium. Due to the difference between ionic valences between the exchanged ions, the provided process behavior is strongly dependent upon the selection of resin properties and to total solution normality. A combination of resin properties and solution normality is provided to achieve the cation exchange.

Abstract: In an embodiment, there is disclosed an inspection method for detecting the presence of imprintable medium on an imprint lithography template. The method includes contacting the imprint lithography template with a marker, the marker being attachable to imprintable medium that may be on the imprint lithography template, the marker being configured to interact with incident radiation when attached to the imprintable medium, directing radiation at the imprint lithography template, and measuring radiation re-directed by the imprint lithography template to attempt to detect presence of a marker that has attached to the imprintable medium, from the interaction of the marker with the incident radiation, and thus detect the presence of imprintable medium to which the marker is attached.

Abstract: A method for determining the styrene microblock content of a copolymer sample, the method comprising: (i) pyrolyzing the copolymer sample to form polymer fragments of the polymer sample; (ii) analyzing the fragments to determine the relative amounts of styrene monomer fragments, styrene dimer fragments, and styrene trimer fragments, where the relative amounts of the fragments include the amount of any given fragment relative to the total of the monomer fragments, dimer fragments, and trimer fragments; and (iii) using the relative amounts of the styrene monomer fragments, styrene dimer fragments, and styrene trimer fragments to predict the polystyrene microblock content from a mathematical model that is based upon the relative styrene monomer fragments, relative styrene dimer fragments, relative styrene trimer fragments, and microblock content of a copolymer having known microblock content.

Abstract: The present invention concerns a method of detecting cationic polymers comprising: obtaining a target water sample containing a cationic polymer; adding a polymer dispersant solution and a phosphate solution to the target water sample, the polymer dispersant solution is comprised of a polymer dispersant with calcium and magnesium hardness and the phosphate solution is comprised of a phosphate; standing the target water sample; and measuring the turbidity of the target water sample; comparing the turbidity of said target water sample with a calibration curve of the turbidity of samples containing known concentrations of cationic polymers to determine the concentration of cationic polymers in said target water sample.

Abstract: A process for purification of water soluble polymers is provided. A polymer of interest can be separated from a mixture of polymers, provided the polymer of interest differs from other polymers in the mixture in the number of reactive terminal groups. The process involves derivatizing polymers at the reactive terminal groups with a derivatizing molecule, bearing either (i) two or three cationic or anionic ionizable groups, and a group capable of covalent bonding to the reactive terminal groups or (ii) three or four ionizable groups, at least one of which is capable of covalent bonding to the reactive terminal groups; followed by ion exchange. The process allows removal of PEG from MPEG, and can be used for polymers having an average size greater than 9,000 Da Derivatization may be reversible in order to allow re-use of recovered contaminant polymers.

Abstract: The diffusion coefficients and relaxation times of mixtures of alkanes follow simple scaling laws based on the chain length of the constituents and the mean chain length of the mixture. These scaling laws are used to determine chain sizes in a mixture from the distribution of the diffusion coefficients. These scaling laws can be used to determine the mean chain lengths (or chain lengths) of a sample (alkanes or mixtures of alkanes) and therefore the constituents of the sample.

Abstract: The present invention provides methods and compositions useful for the diagnosis or prognosis of a systemic inflammatory condition such as sepsis.

Abstract: In one aspect, the invention is directed to a method for determining the concentration of anionic polymers or oligomers in industrial water comprising combining a buffer solution and a cationic dye solution, measuring absorbance of the buffer-dye admixture at selected wavelength(s) and determining the polymer or oligomer concentration from the previously determined absorbance values. In alternate embodiments of the invention, the buffer solution may be a multifunctional buffer solution and may be comprised of multiple buffers, masking agents. and/or stabilizing agents and combinations thereof. Other embodiments provide that multiple dyes may be employed.

Abstract: The invention provides methods and apparatus for characterizing complex polymeric mixture of interest. Candidate solutions are eliminated from a solution space using one or more experimental measurements of a polymeric mixture of interest. The elimination step can be repeated one or more times using different experimental measurements produced by various chemical and physical protocols, so that the remaining candidate solutions converge to describe the actual polymeric mixture under investigation. Once the composition of the complex polymeric mixture has been characterized, the information thus generated can be used to facilitate, for example, the manufacture of a bio-equivalent of the complex polymeric mixture.

Abstract: The present invention provides methods for identifying whether or not a patient has, or is at risk of developing drug induced organ damage and methods of treating patients having drug induced organ damage. In particular, the invention relates to a method for identifying whether or not a patent has, or is at risk of developing paracetamol induced liver damage.

Abstract: The present invention intends to provide a high sensitivity method for identifying the type of a protein contained in each cell with a diameter of ten to several tens ?m and a sample treatment solution required for it. The above is achieved by three steps of (1) treating a slice of a diseased tissue with an aqueous solution containing gold particles and a digestive enzyme, and digesting restrictively a protein of interest, (2) measuring a 2-dimensional distribution of fragmented peptides by TOF-SIMS, and (3) visualizing a 2-dimensional distribution of the target protein in the slice of the diseased tissue using the results of the proteome analysis and by means of a numerical analysis.

Abstract: The present invention is directed to methods for assessing the purity of carbon nanotube (CNT) compositions, specifically, a method for assessing the presence of contaminants in a CNT composition using polyaryl ethynyl (PAE) conjugate polymer as an indicator material. Additionally, compositions and kits comprising a polyaryl ethynyl (PAE) conjugate polymer are also provided.

Abstract: Devices and methods for immobilizing micrometer sized liquid domains onto a chemically functionalized substrate surface are disclosed. A multifunctional polymer is adsorbed at the surface interface of the liquid microdomains, and the liquid microdomains are immobilized by covalent bonding or non-covalent forces such as electrostatic attraction between the adsorbed multifunctional polymer and the functionalized substrate surface.

Abstract: A method for evaluating rubber is provided which can evaluate the degree of crosslinking of a crosslinked rubber product within a short period of time without performing any specific treatment. In the above method, the amount of energy shift of the peak (such as the peak of C12p3/2 of chlorinated butyl rubber) of a constituent element of the rubber is measured by photoelectron spectroscopy, and the degree of crosslinking of the rubber is evaluated from the amount of energy shift. In addition, a method for manufacturing a rubber product is also provided which includes the steps of measuring the amount of energy shift of the peak of a constituent element of the rubber product by a photoelectron spectrometer which is installed in a manufacturing line and then feeding back measurement result to adjust heat molding conditions so as to obtain a desired degree of crosslinking.

Abstract: A method and apparatus for chromatography of a polyolefin polymer by flowing a solution of the polyolefin polymer through liquid flowing through a graphitic carbon liquid chromatography stationary phase. The method can be used to determine the monomer to comonomer ratio of a polyolefin copolymer such as a copolymer of ethylene and 1-octene or a copolymer of propylene and ethylene.