Having Biomaterial Component Or Integrated With Living Organism Patents (Class 438/1)
  • Patent number: 10944398
    Abstract: An article of manufacture comprising doped, colloidal nanostructures that are configured to have a plasmonic response to light of a first resonance wavelength.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: March 9, 2021
    Assignee: UChicago Argonne, LLC
    Inventors: Richard Schaller, Benjamin Diroll
  • Patent number: 10920340
    Abstract: A gas phase nanowire growth apparatus including a reaction chamber, a first input and a second input. The first input is located concentrically within the second input and the first and second input are configured such that a second fluid delivered from the second input provides a sheath between a first fluid delivered from the first input and a wall of the reaction chamber.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: February 16, 2021
    Assignee: AlignedBio AB
    Inventors: Greg Alcott, Martin Magnusson, Olivier Postel, Knut Deppert, Lars Samuelson, Jonas Ohlsson
  • Patent number: 10879005
    Abstract: In electronic devices, as a result of miniaturization, the distance between a mounting board and an upper board or a shield case and the like, or the distance between the mounting board and other electronic components mounted adjacent thereto has become smaller. An electronic component is provided with: an element body internally containing a circuit element; and a terminal formed on the element body. The terminal is formed over an end surface of the element body and a surface adjacent to the end surface. An insulating film covering the terminal is formed on the element body. The terminal is exposed from the insulating film at least at a mounting surface of the element body, and a plating film containing tin is formed on a portion of the terminal exposed from the insulating film.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: December 29, 2020
    Assignee: Murata Manufacturing Co., Ltd.
    Inventors: Yoshifumi Maki, Hirotsugu Tomioka, Shinichiro Izumi, Eiji Iso
  • Patent number: 10696769
    Abstract: Provided herein are polymeric compositions having a relaxation time that is a function of pH. The polymeric compositions can include an anionic monomer, a cationic monomer, and a crosslinker. The crosslinker may comprise at least one of a diacrylate crosslinker and a dimethacrylate crosslinker. Also provided herein are methods of pH sensing, and methods of forming a polymeric composition. Kits of parts also are provided that include a polymeric composition. The polymeric compositions may be used to determine the pH of one or more biological tissues and/or liquids.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: June 30, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Gregory James Ekchian, Michael John Cima
  • Patent number: 10589467
    Abstract: Complexity of a geometry of a desired (i.e., target) three-dimensional (3D) object being produced by an additive manufacturing system, as well as atypical behavior of the processes employed by such a system, pose challenges for producing a final version of the desired 3D object with fidelity relative to the desired object. An example embodiment enables such challenges to be overcome as a function of feedback to enable the final version to be produced with fidelity. The feedback may be at least one value that is associated with at least one characteristic of a printed object following processing of the printed object. Such feedback may be obtained as part of a calibration process of the 3D printing system or as part of an operational process of the 3D printing system.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: March 17, 2020
    Assignee: Desktop Metal, Inc.
    Inventors: Jay Tobia, Nihan Tuncer, Aaron Preston, Ricardo Fulop, Michael A. Gibson, Richard Remo Fontana, Anastasios John Hart
  • Patent number: 10580810
    Abstract: A solid-state image sensor includes: a pixel array that includes first pixels, each having first and second photoelectric conversion units, and second pixels, each having third and fourth photoelectric conversion units; first to fourth transfer gates via which a signal charge respectively generated in the first to fourth photoelectric conversion units is respectively transferred to first to fourth charge voltage conversion units. At least one of a gate width, a gate length and an installation position of at least one transfer gate among the first to fourth transfer gates is altered to achieve uniformity in voltage conversion efficiency at the first to fourth charge voltage conversion units.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: March 3, 2020
    Assignee: NIKON CORPORATION
    Inventor: Satoshi Suzuki
  • Patent number: 10529758
    Abstract: A method for forming an image sensor package and an image sensor package are provided. The method includes: providing a first substrate and a second substrate which includes a first surface and a second surface opposite to the first surface, and attaching either surface of the first substrate with the first surface of the second substrate with an adhesive layer; forming a groove at the second surface of the second substrate; providing a base which includes a first surface and a second surface opposite to the first surface, where the first surface of the base is provided with a sensing region and multiple contact pads; and attaching the second surface of the second substrate with the first surface of the base, where a cavity is formed between the groove and the base, and the sensing region is located within the cavity.
    Type: Grant
    Filed: September 21, 2015
    Date of Patent: January 7, 2020
    Assignee: China Wafer Level CSP Co., Ltd.
    Inventors: Zhiqi Wang, Qiong Yu, Wei Wang
  • Patent number: 10472150
    Abstract: Provided herein is a moisture barrier film for packaging, such as tobacco or cigarette packaging. The film comprises polylactic acid (“PLA”) that is both biodegradable and transparent. The film includes multiple layers of PLA, with a base layer having a relatively high melting point compared to two outer layers, which have a relatively low melting point. The outer layers provide heat sealing capabilities to the film. The film is coated with a metal oxide layer comprised of aluminum oxide, titanium oxide, and/or aluminum-titanium oxide using an atomic layer deposition (“ALD”) coating method. The ALD coating to the PLA film results in a moisture transmission rate of less than 4 g/m2/day after the film has been subjected to creasing, which induces cracking of the ALD metal oxide layer.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: November 12, 2019
    Assignee: R.J. REYNOLDS TOBACCO PRODUCTS
    Inventors: Andries Don Sebastian, Sami Ilmari Sneck, Mikko Juhani Söderlund
  • Patent number: 10367467
    Abstract: A composite electronic component includes a capacitor component and an inductor component. A capacitor body has a first end face and a second end face that are opposed to each other in a longitudinal direction and a first side face. At least one of capacitor outer electrodes is provided on the first end face of the capacitor body. An inductor body has a first end face and a second end face that are opposed to each other in the longitudinal direction and a first side face. At least one of inductor outer electrodes is provided on the first end face of the inductor body. The first side face of the capacitor body is opposed to the first side face of the inductor body, and the first end face of the capacitor body and the first end face of the inductor body are positioned in the same direction.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: July 30, 2019
    Assignee: Murata Manufacturing Co., Ltd.
    Inventors: Takanao Mizushima, Kazuhide Kudo
  • Patent number: 10190083
    Abstract: A device for interfacing coatings, the device comprising at least one well each comprising an elastomeric bottom surface. At least one slit is formed on the elastomeric bottom surface. At least one removable divider is removably inserted into the at least one slit, whereby at least one gap is created and the at least one well is divided into at least two compartments. A designated coating is lined on the elastomeric bottom surface of each of the at least two compartments. Removal of the at least one removable divider then causes the at least one gap to close, allowing for the designated coatings lined on the elastomeric bottom surface of each of the at least two compartments to interface with each other.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: January 29, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Elliot En-Yu Hui, Jiang Li, Monica Young Kim, Allison Lee Curtis
  • Patent number: 10084103
    Abstract: A thin film and a method of making a thin film. The thin film comprises a patterned substrate, a smooth film of electric field tuned quantum dots solution positioned on the patterned substrate, and a thin layer of metal positioned on the thin film. The method begins by drop-casting a quantum dots solution onto a patterned substrate to create a thin film. While the quantum dots solution is drying, a linearly increasing electric filed is applied. The thin film is then placed in a deposition chamber and a thin layer of metal is deposited onto the thin film. Also included are a method of measuring the photoinduced charge transfer (PCT) rate in a quantum dot nanocomposite film and methods of forming a Shottky barrier on a transparent ITO electrode of a quantum dot film.
    Type: Grant
    Filed: November 4, 2013
    Date of Patent: September 25, 2018
    Assignee: University of South Florida
    Inventors: Jason Lewis, Xiaomei Jiang
  • Patent number: 10065218
    Abstract: A solidified body forming step includes: a first step of landing a processing surface of a cooling member on a liquid film to solidify the liquid to be solidified located in an area sandwiched between an upper surface and the processing surface; and a second step of releasing the processing surface from the solidified area solidified in the first step. The processing surface has a lower temperature than a freezing point of the liquid to be solidified. Adhesion between the solidified area and the processing surface is smaller than that between the solidified area and the upper surface.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: September 4, 2018
    Assignee: SCREEN Holdings Co., Ltd.
    Inventors: Hiroaki Kitagawa, Katsuhiko Miya
  • Patent number: 9985202
    Abstract: A method of fabricating a memory device, the method including forming a first magnetization layer; forming a tunnel barrier layer on the first magnetization layer; forming a second magnetization layer on the tunnel barrier layer; forming a magnetic tunnel junction (MTJ) structure by patterning the first magnetization layer, the tunnel barrier layer, and the second magnetization layer; and forming a boron oxide in a sidewall of the MTJ structure by implanting boron.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: May 29, 2018
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Jeong-heon Park, Se-chung Oh, Byoung-jae Bae, Jong-chul Park
  • Patent number: 9850951
    Abstract: A bearing component having a ceramic surface, the ceramic surface including a plurality of pores, and at least some of the pores are at least partially filled with a resin comprising a resole phenolic resin.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: December 26, 2017
    Assignee: AKTIEBOLAGET SKF
    Inventors: Karl Preis, Helmut Weninger, Xiaobo Zhou
  • Patent number: 9620558
    Abstract: A solid-state image sensor includes: a pixel array that includes first pixels, each having first and second photoelectric conversion units, and second pixels, each having third and fourth photoelectric conversion units; first to fourth transfer gates via which a signal charge respectively generated in the first to fourth photoelectric conversion units is respectively transferred to first to fourth charge voltage conversion units. At least one of a gate width, a gate length and an installation position of at least one transfer gate among the first to fourth transfer gates is altered to achieve uniformity in voltage conversion efficiency at the first to fourth charge voltage conversion units.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: April 11, 2017
    Assignee: NIKON CORPORATION
    Inventor: Satoshi Suzuki
  • Patent number: 9478410
    Abstract: Disclosed is a method of forming a nitride film on a substrate to be processed (“processing target substrate”) in a processing container. The method includes an adsorption step of supplying a precursor gas including a silicon-containing gas into the processing container, and adsorbing a molecule of the precursor gas onto a surface of the processing target substrate, and a reaction step of supplying a reaction gas including a nitrogen- and hydrogen-containing gas while supplying microwaves from an antenna to generate plasma of the reaction gas just above the processing target substrate, and performing a plasma processing, by the generated plasma, on a surface of the substrate to be processed on which the molecule of the precursor gas has been adsorbed.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: October 25, 2016
    Assignee: Tokyo Electron Limited
    Inventors: Toyohiro Kamada, Noriaki Fukiage, Takayuki Karakawa
  • Patent number: 9419050
    Abstract: A manufacturing method of a semiconductor structure includes the following steps. A temporary bonding layer is used to adhere a carrier to a first surface of a wafer. A second surface of the wafer is adhered to an ultraviolet tape on a frame, and the temporary bonding layer and the carrier are removed. A protection tape is adhered to the first surface of the wafer. An ultraviolet light is used to irradiate the ultraviolet tape. A dicing tape is adhered to the protection tape and the frame, and the ultraviolet tape is removed. A first cutter is used to dice the wafer from the second surface of the wafer, such that plural chips and plural gaps between the chips are formed. A second cutter with a width smaller than the width of the first cutter is used to cut the protection tape along the gaps.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: August 16, 2016
    Assignee: XINTEC INC.
    Inventors: Yen-Shih Ho, Shu-Ming Chang, Yung-Tai Tsai, Tsang-Yu Liu
  • Patent number: 9410911
    Abstract: A structure for a chemical sensing device, the structure comprising at least one electrically conductive element located in, and protruding from, at least one recess. A method of manufacturing the structure includes: (a) providing a template comprising at least one recess having a recess depth; (b) providing an electrically conductive material in the at least one recess; and (c) removing part of the template to decrease the recess depth of the at least one recess, thereby forming said protruding at least one electrically conductive element.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: August 9, 2016
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Kevin Dooley, Richard Coull, Graeme Scott, Lorraine Byrne
  • Patent number: 9297796
    Abstract: Kinked nanowires are used for measuring electrical potentials inside simple cells. An improved intracellular entrance is achieved by modifying the kinked nanowires with phospholipids.
    Type: Grant
    Filed: September 24, 2010
    Date of Patent: March 29, 2016
    Assignee: President and Fellows of Harvard College
    Inventors: Bozhi Tian, Ping Xie, Thomas J. Kempa, Charles M. Lieber, Itzhaq Cohen-Karni, Quan Qing, Xiaojie Duan
  • Patent number: 9024403
    Abstract: An image sensor package and image sensor chip capable of being slenderized while enhancing the reliability with respect to physical impact are provided. The image sensor package includes an image sensor chip provided with a pixel domain at a central portion of an upper surface thereof, a substrate disposed at an upper side of the image sensor chip so as to be flip-chip bonded with respect to the image sensor chip, provided with a hole formed at a position corresponding to the pixel domain, and formed of organic material, a printed circuit board at which the substrate provided with the image sensor chip bonded thereto is mounted, and a solder ball configured to electrically connect the substrate to the printed circuit board.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: May 5, 2015
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Tae Sang Park, Hyo Young Shin
  • Publication number: 20150108425
    Abstract: A method of fabricating a nanoshell is disclosed. The method comprises coating a nanometric core made of a first material by a second material, to form a core-shell nanostructure and applying non-chemical treatment to the core-shell nanostructure so as to at least partially remove the nanometric core, thereby fabricating a nanoshell. The disclosed nanoshell can be used in the fabrication of transistors, optical devices (such as CCD and CMOS sensors), memory devices and energy storage devices.
    Type: Application
    Filed: May 21, 2013
    Publication date: April 23, 2015
    Applicant: Tower Semiconductor Ltd.
    Inventors: Gil Rosenman, Simon Litsyn, Yakov Roizin
  • Publication number: 20150011021
    Abstract: The present disclosure provides biochips and methods of fabricating biochips. The method includes combining three portions: a transparent substrate, a first substrate with microfluidic channels therein, and a second substrate. Through-holes for inlet and outlet are formed in the transparent substrate or the second substrate. Various non-organic landings with support medium for bio-materials to attach are formed on the first substrate and the second substrate before they are combined. In other embodiments, the microfluidic channel is formed of an adhesion layer between a transparent substrate and a second substrate with landings on the substrates.
    Type: Application
    Filed: September 25, 2014
    Publication date: January 8, 2015
    Inventors: Chia-Hua Chu, Allen Timothy Chang, Ching-Ray Chen, Yi-Hsien Chang, Yi-Shao Liu, Chun-Ren Cheng, Chun-Wen Cheng
  • Patent number: 8895965
    Abstract: Provided is a photoelectric conversion element including a photoconductor containing a complex of a conductive polymer and/or polymer semiconductor and a protein containing at least one dye having a long-lived excited state.
    Type: Grant
    Filed: February 22, 2012
    Date of Patent: November 25, 2014
    Assignee: Sony Corporation
    Inventors: Wei Luo, Yuichi Tokita, Yoshio Goto, Seiji Yamada, Satoshi Nakamaru
  • Patent number: 8877112
    Abstract: The present invention relates to an article fabrication system having a plurality of material deposition tools containing one or more materials useful in fabricating the article, and a material deposition device having a tool interface for receiving one of the material deposition tools. A system controller is operably connected to the material deposition device to control operation of the material deposition device. Also disclosed is a method of fabricating an article using the system of the invention and a method of fabricating a living three-dimensional structure.
    Type: Grant
    Filed: January 2, 2014
    Date of Patent: November 4, 2014
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Lawrence Bonassar, Hod Lipson, Daniel L. Cohen, Evan Malone
  • Publication number: 20140312879
    Abstract: A transistor includes at least one conductive layer, at least one gate dielectric layer and at least one semiconducting film deposited on top of a receptor molecule layer previously deposited or covalently linked to the surface of the gate dielectric. The layer of biological material includes single or double layers of phospholipids, layers made of proteins such as receptors, antibodies, ionic channels and enzymes, single or double layers of phospholipids with inclusion or anchoring of proteins such as: receptors, antibodies, ionic channels and enzymes, layers made of oligonucleotide (DNA, RNA, PNA) probes, layers made of cells or viruses, layers made of synthetic receptors for example molecules or macromolecules similar to biological receptors for properties, reactivity or steric aspects.
    Type: Application
    Filed: October 31, 2011
    Publication date: October 23, 2014
    Applicants: UNIVERSITÁ DEGLI STUDI DI BARI, Consiglio Nazionale delle Ricerche Istituto Pro- cessi Chimico Fisici-IPCF
    Inventors: Luisa Torsi, Gerardo Palazzo, Nicola Cioffi, Maria Daniela Angione, Maria Magliulo, Serafina Cotrone, Gaetano Scamarcio, Luigia Sabbatini, Antonia Malllardi
  • Patent number: 8846416
    Abstract: The present disclosure provides biochips and methods of fabricating biochips. The method includes combining three portions: a transparent substrate, a first substrate with microfluidic channels therein, and a second substrate. Through-holes for inlet and outlet are formed in the transparent substrate or the second substrate. Various non-organic landings with support medium for bio-materials to attach are formed on the first substrate and the second substrate before they are combined. In other embodiments, the microfluidic channel is formed of an adhesion layer between a transparent substrate and a second substrate with landings on the substrates.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: September 30, 2014
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Chia-Hua Chu, Allen Timothy Chang, Ching-Ray Chen, Yi-Hsien Chang, Yi-Shao Liu, Chun-Ren Cheng, Chun-Wen Cheng
  • Publication number: 20140273281
    Abstract: The present disclosure provides biochips and methods of fabricating biochips. The method includes combining three portions: a transparent substrate, a first substrate with microfluidic channels therein, and a second substrate. Through-holes for inlet and outlet are formed in the transparent substrate or the second substrate. Various non-organic landings with support medium for bio-materials to attach are formed on the first substrate and the second substrate before they are combined. In other embodiments, the microfluidic channel is formed of an adhesion layer between a transparent substrate and a second substrate with landings on the substrates.
    Type: Application
    Filed: March 13, 2013
    Publication date: September 18, 2014
    Inventors: Chia-Hua Chu, Allen Timothy Chang, Ching-Ray Chen, Yi-Hsien Chang, Yi-Shao Liu, Chun-Ren Cheng, Chun-Wen Cheng
  • Patent number: 8772099
    Abstract: A method of detecting a detection target using a sensor requires a sensor having a transistor selected from the group of field-effect transistors or single electron transistors. The transistor includes a substrate, a source electrode disposed on the substrate and a drain electrode disposed on the substrate, and a channel forming a current path between the source electrode and the drawing electrode; an interaction-sensing gate comprising a specific substance; and a voltage gate. The method includes (a) providing the detection target on the interaction-sensing gate; (b) setting the gate voltage in the voltage gate at a predetermined level; (c) selectively interacting the specific substance with the detection target; (d) when the detection target interacts with the specific substance, changing a gate voltage in the voltage gate to adjust a characteristic of the transistor; and (e) measuring a change in the characteristic of the transistor to determine a presence of the detection target.
    Type: Grant
    Filed: July 24, 2012
    Date of Patent: July 8, 2014
    Assignee: Japan Science and Technology Agency
    Inventors: Kazuhiko Matsumoto, Atsuhiko Kojima, Satoru Nagao, Masanori Katou, Yutaka Yamada, Kazuhiro Nagaike, Yasuo Ifuku, Hiroshi Mitani
  • Publication number: 20140183487
    Abstract: A conductivity type of a protein semiconductor is controlled by controlling total amount of charge in amino acid residues, a p-type protein semiconductor or an n-type protein semiconductor is manufactured, and a pn junction is manufactured using the p-type protein semiconductor and the n-type protein semiconductor. The total amount of charge in amino acid residues is controlled by substituting one or more of an acidic amino acid residue, a basic amino acid residue, and a neutral amino acid residue, which are contained in protein, with an amino acid residue having different properties, chemically modifying one or more of an acidic amino acid residue, a basic amino acid residue, and a neutral amino acid residue, which are contained in the protein, or controlling polarity of a medium surrounding the protein.
    Type: Application
    Filed: May 16, 2012
    Publication date: July 3, 2014
    Applicant: Sony Corporation
    Inventors: Yuichi Tokita, Yoshio Goto, Wei Luo, Satoshi Nakamaru, Seiji Yamada
  • Patent number: 8741679
    Abstract: The NH3 plasma treatment by remote plasma is firstly proposed to replace the covalent bonding process during surface modification procedure that for amine bond generation.
    Type: Grant
    Filed: May 8, 2012
    Date of Patent: June 3, 2014
    Assignee: Chang Gung University
    Inventors: Chao-Sung Lai, Jau-Song Yu, Yu-Sun Chang, Po-Lung Yang, Tseng-Fu Lu, Yi-Ting Lin, Wen-Yu Chuang, Ting-Chun Yu, I-Shun Wang, Jyh-Ping Chen, Chou Chien
  • Publication number: 20140124739
    Abstract: One aspect of the invention provides a self-assembled quantum computer including a plurality of quantum dots coupled by binding domains. Another aspect of the invention provides a method of self-assembling a quantum computer. The method includes: providing a plurality of quantum dots, each of the quantum dots coupled to between one and six binding domains; and facilitating coupling of the quantum dots through the binding domains, thereby self-assembling a quantum computer.
    Type: Application
    Filed: November 8, 2013
    Publication date: May 8, 2014
    Applicant: THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION
    Inventor: Russell J. Deaton
  • Patent number: 8697469
    Abstract: The present invention discloses a protein transistor device, wherein an antibody molecule (antibody-antigen) is bonded to at least two gold nanoparticles in a high reproducible self-assembly way to form molecular junctions, and wherein the two gold nanoparticles are respectively joined to a drain and a source. The protein transistor device can be controlled to regulate current via applying a bias to the gate. The conformational change of the protein molecule will cause the variation of the charge transport characteristics of the protein transistor device. The protein transistor device can be further controlled by different optical fields via conjugating a quantum dot to the molecular junctions. Therefore, the present invention has diversified applications.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: April 15, 2014
    Assignee: National Chiao Tung University
    Inventors: Gue-Wha Huang, Meng-Yen Hung, Yu-Shiun Chen
  • Patent number: 8683367
    Abstract: A method for differentiating between variations of an apparatus design is provided. The method includes digitally characterizing at least two aspects of a first expression wherein the at least two aspects include at least logical data and physical data relating to the first expression, and digitally characterizing the at least two next aspects of at least one next expression other than the first expression wherein the at least two next aspects include at least logical data and physical data relating to the at least one next design expression. The method further includes identifying selected differences between the at least two aspects and the at least two next aspects and displaying the first expression and at least one of the at least one next expression in a visual display wherein the selected differences are presented using at least one visually identifiable distinction.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: March 25, 2014
    Assignee: The Boeing Company
    Inventors: Brent Louis Hadley, Patrick J. Eames, Michael Patrick Sciarra
  • Publication number: 20140073063
    Abstract: The present invention generally relates to nanoscale wires and tissue engineering. Systems and methods are provided in various embodiments for preparing cell scaffolds that can be used for growing cells or tissues, where the cell scaffolds comprise nanoscale wires. In some cases, the nanoscale wires can be connected to electronic circuits extending externally of the cell scaffold. Such cell scaffolds can be used to grow cells or tissues which can be determined and/or controlled at very high resolutions, due to the presence of the nanoscale wires, and such cell scaffolds will find use in a wide variety of novel applications, including applications in tissue engineering, prosthetics, pacemakers, implants, or the like. This approach thus allows for the creation of fundamentally new types of functionalized cells and tissues, due to the high degree of electronic control offered by the nanoscale wires and electronic circuits.
    Type: Application
    Filed: September 4, 2013
    Publication date: March 13, 2014
    Applicant: President and Fellows of Harvard College
    Inventors: Charles M. Lieber, Bozhi Tian, Jia Liu
  • Publication number: 20140048776
    Abstract: The present invention discloses a protein transistor device, wherein an antibody molecule (antibody-antigen) is bonded to at least two gold nanoparticles in a high reproducible self-assembly way to form molecular junctions, and wherein the two gold nanoparticles are respectively joined to a drain and a source. The protein transistor device can be controlled to regulate current via applying a bias to the gate. The conformational change of the protein molecule will cause the variation of the charge transport characteristics of the protein transistor device. The protein transistor device can be further controlled by different optical fields via conjugating a quantum dot to the molecular junctions. Therefore, the present invention has diversified applications.
    Type: Application
    Filed: November 30, 2012
    Publication date: February 20, 2014
    Applicant: NATIONAL CHIAO TUNG UNIVERSITY
    Inventors: Gue-Wha HUANG, Meng-Yen HUNG, Yu-Shiun CHEN
  • Patent number: 8653616
    Abstract: It is aimed to provide a photoelectric conversion device having high adhesion between a first semiconductor layer and an electrode layer as well as high photoelectric conversion efficiency. A photoelectric conversion device comprises an electrode layer, a first semiconductor layer located on the electrode layer and comprising a chalcopyrite-based compound semiconductor of group I-III-VI and oxygen, and a second semiconductor layer located on the first semiconductor layer and forming a pn junction with the first semiconductor layer. In the photoelectric conversion device, the first semiconductor layer has a higher molar concentration of oxygen in a part located on the electrode layer side with respect to a center portion in a lamination direction of the first semiconductor layer than a molar concentration of oxygen in the whole of the first semiconductor layer.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: February 18, 2014
    Assignee: KYOCERA Corporation
    Inventors: Rui Kamada, Shuichi Kasai
  • Patent number: 8636938
    Abstract: The present invention relates to an article fabrication system having a plurality of material deposition tools containing one or more materials useful in fabricating the article, and a material deposition device having a tool interface for receiving one of the material deposition tools. A system controller is operably connected to the material deposition device to control operation of the material deposition device. Also disclosed is a method of fabricating an article using the system of the invention and a method of fabricating a living three-dimensional structure.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: January 28, 2014
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Lawrence Bonassar, Hod Lipson, Daniel L. Cohen, Evan Malone
  • Patent number: 8623496
    Abstract: A method of forming extremely small pores in a substrate that is used, for example, in patch clamp applications is provided that employs an energy absorbing material beyond a back side of the substrate to allow a laser to be focused adjacent the exit side of the substrate so as to generate a pore through the substrate and can also form a crater in the back side of the substrate and in which the pore may propagate from the crater in a drilling direction that can oppose a laser transmission direction.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: January 7, 2014
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Robert H. Blick, Minrui Yu
  • Publication number: 20140000688
    Abstract: A method of a general biological approach to synthesizing compact nanotubes using a biological template is described.
    Type: Application
    Filed: June 10, 2013
    Publication date: January 2, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Xiangnan Dang, Hyunjung Yi, Angela M. Belcher, Paula T. Hammond
  • Patent number: 8618581
    Abstract: A field effect transistor device includes: a reservoir bifurcated by a membrane of three layers: two electrically insulating layers; and an electrically conductive gate between the two insulating layers. The gate has a surface charge polarity different from at least one of the insulating layers. A nanochannel runs through the membrane, connecting both parts of the reservoir. The device further includes: an ionic solution filling the reservoir and the nanochannel; a drain electrode; a source electrode; and voltages applied to the electrodes (a voltage between the source and drain electrodes and a voltage on the gate) for turning on an ionic current through the ionic channel wherein the voltage on the gate gates the transportation of ions through the ionic channel.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: December 31, 2013
    Assignee: International Business Machines Corporation
    Inventors: Hongbo Peng, Stanislav Polonsky, Stephen M. Rossnagel, Gustavo Alejandro Stolovitzky
  • Patent number: 8603836
    Abstract: Disclosed is a transparent carbon nanotube (CNT) electrode using a conductive dispersant. The transparent CNT electrode comprises a transparent substrate and a CNT thin film formed on a surface the transparent substrate wherein the CNT thin film is formed of a CNT composition comprising CNTs and a doped dispersant. Further disclosed is a method for producing the transparent CNT electrode. The transparent CNT electrode exhibits excellent conductive properties, can be produced in an economical and simple manner by a room temperature wet process, and can be applied to flexible displays. The transparent CNT electrode can be used to fabricate a variety of devices, including image sensors, solar cells, liquid crystal displays, organic electroluminescence (EL) displays and touch screen panels, that are required to have both light transmission properties and conductive properties.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: December 10, 2013
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Seon Mi Yoon, Jae Young Choi, Dong Kee Yi, Seong Jae Choi, Hyeon Jin Shin
  • Patent number: 8592227
    Abstract: Embodiments of the present disclosure include hybrid quantum dot/protein nanostructure, hybrid quantum dot/protein nanostructure systems, methods of using hybrid quantum dot/protein nanostructures, and the like.
    Type: Grant
    Filed: May 4, 2011
    Date of Patent: November 26, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Nan Ma, Jianghong Rao
  • Patent number: 8569063
    Abstract: Disclosed is a method for manufacturing a plurality of gold nanoparticles in a plant, the method comprising growing the plant hydroponically, contacting at least a first part of the plant with a substance comprising at least one gold salt, providing an average photosynthetic active radiation (PAR) to at least second part of the plant, waiting a period of time sufficient for formation of a plurality of gold nanoparticles in at least a portion of the plant, thereby manufacturing the plurality of gold nanoparticles in the plant. Disclosed also are, inter alia, a plurality of gold nanoparticles manufactured by such a method; an article of manufacture comprising a plurality of gold nanoparticles manufactured by such a method; and a plurality of triangular gold nanoparticles manufactured by such a method.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: October 29, 2013
    Assignee: Western Kentucky University Research Foundation
    Inventors: Shivendra Vikram Sahi, Ajay Jain
  • Patent number: 8470611
    Abstract: A method of a general biological approach to synthesizing compact nanotubes using a biological template is described.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: June 25, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Xiangnan Dang, Hyunjung Yi, Angela M. Belcher, Paula T. Hammond
  • Patent number: 8460524
    Abstract: Methods and systems for measuring the concentration of an analyte in a blood sample and, more particularly, to methods of chemistry patterning reagent layers for multiple well biosensors. A first capillary is first configured to receive a dispensed reagent layer such that the reagent layer is distributed in a substantially uniform manner within the first capillary. The first capillary may also configured to isolate the first capillary from other capillaries present in the biosensor. After the reagent layer has been dispensed and dried, the first capillary may then be reconfigured to allow the first capillary to receive a blood sample.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: June 11, 2013
    Assignee: Nipro Diagnostics, Inc.
    Inventors: Natasha Popovich, Gary T. Neel, William Milo, Zachary Thomas, Stephen Davies
  • Patent number: 8455966
    Abstract: Provided are transistor devices such as logic gates that are capable of associating a computational state and or performing logic operations with detectable electronic spin state and or magnetic state. Methods of operating transistor devices employing magnetic states are provided. Devices comprise input and output structures and magnetic films capable of being converted between magnetic states.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: June 4, 2013
    Assignee: Intel Corporation
    Inventors: C Michael Garner, Dmitri E. Nikonov
  • Publication number: 20130119499
    Abstract: Apparatus, compositions, methods, and articles of manufacture are disclosed relating to the design and production of biological components and/or their incorporation in devices and systems, including biohybrid photosensitive devices and systems. In some embodiments, biological components include light antenna structures that collect light and emit Stokes-shifted light to a photoactive non-biological component. In some embodiments, the characteristics of biological components are engineered via force-adaptation of an organism or adaptive system. In some embodiments, biological components are modified by removing reaction centers or other structure not contributing to desired performance.
    Type: Application
    Filed: May 8, 2012
    Publication date: May 16, 2013
    Inventors: Jeffrey T. LaBelle, Vincent B. Pizziconi
  • Publication number: 20130098762
    Abstract: A patch clamp system providing precise and rapid temperature control of constrained cell membranes employs the thermal element attached to the substrate of the patch clamp. In one embodiment, the thermal element is a Peltier device fabricated on a silicon membrane wafer bonded to the substrate of the patch clamp.
    Type: Application
    Filed: October 21, 2011
    Publication date: April 25, 2013
    Inventor: Robert H. Blick
  • Publication number: 20130039859
    Abstract: Passivated semiconductor nanoparticles and methods for the fabrication and use of passivated semiconductor nanoparticles is provided herein.
    Type: Application
    Filed: September 23, 2010
    Publication date: February 14, 2013
    Inventors: Lianhua Qu, Gregory Miller
  • Patent number: 8357547
    Abstract: A method of manufacturing a semiconductor bio-sensor comprises providing a substrate, forming a first dielectric layer on the substrate, forming a patterned first conductive layer on the first dielectric layer, the patterned first conductive layer including a first portion and a pair of second portions, forming a second dielectric layer, a third dielectric layer and a fourth dielectric layer in sequence over the patterned first conductive layer, forming cavities into the fourth dielectric layer, forming vias through the cavities, exposing the second portions of the patterned first conductive layer, forming a patterned second conductive layer on the fourth dielectric layer, forming a passivation layer on the patterned second conductive layer, forming an opening to expose a portion of the third dielectric layer over the first portion of the patterned first conductive layer, and forming a chamber through the opening.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: January 22, 2013
    Assignee: Macronix International Co., Ltd.
    Inventors: Ming-Tung Lee, Shih-Chin Lien, Chia-Huan Chang