Abstract: Bioabsorbable biocompatible polymers which provide a good match between their properties and those of certain tissue structures are provided. The bioabsorbable biocompatible polymers can be prepared with tensile strengths, elongation to breaks, and/or tensile modulus (Young's modulus) values of the tissues of the cardiovascular, gastrointestinal, kidney and genitourinary, musculoskeletal, and nervous systems, as well as those of the oral, dental, periodontal, and skin tissues. Methods for processing the bioabsorbable biocompatible polymers into tissue engineering devices are also provided.

Abstract: A non-invasive, in vivo method for measuring sub-clinical or clinical inflammation or irritation of mammalian skin from exposure of the skin to a topical skin care product, exposure to an external aggression or combinations thereof is disclosed. In one embodiment, the method includes the steps of collecting eicosanoid from the skin using a non-invasive collection device and analyzing levels of eicosanoid collected from the skin. A kit for measuring a marker of skin irritation or inflammation is also disclosed. The kit includes a non-invasive collection device for collecting secretions from the skin surface, and an immunoassay for measuring level of eicosanoid in the secretions.

Abstract: Biocidal polyester fabrics, fibers and other materials, and methods of preparation. Heterocyclic N-halamine precursor moieties are covalently linked to the polyester material. The fabrics or fibers obtain antimicrobial activity after washing with a source of oxidative halogen such as a chlorine bleach by conversion of the precursor moieties into N-halamine functionalities. The antimicrobial activity can be repeatedly regenerated by further washing with aqueous oxidative halogen. The biocidal polyester fabrics, fibers, and other materials will be effective in reducing, or eliminating entirely, pathogenic and odor-causing microorganisms.

Abstract: An apparatus and method are described for treating one or more yarn strands before or after the strand is dyed. The apparatus preferably includes a modified space dyeing apparatus having a dye applicator modified to be used as a treatment composition applicator for treating a yarn strand. The apparatus enables a high speed yarn dyeing and treatment method. Also described is a method and composition for treating yarn with a polyphenolic derivative composition to form a bleach-resistant yarn.

Abstract: The object of the present invention is to provide: a hybrid material for regeneration of living body tissue, which can retain sufficient mechanical strength for a term needed to regenerate the tissue, and which simultaneously has moderate biodegradation absorbability which enables degradation and disappearance rapidly after the regeneration of the tissue. As means for solving the problems, the hybrid material for regeneration of living body tissue, according to the present invention, comprises a naturally-occurring polymer and a biodegradation-absorbable synthetic polymer, wherein the biodegradation-absorbable synthetic polymer exists in a fibrous form in a sponge including the naturally-occurring polymer, and wherein the naturally-occurring polymer is crosslinked.

Abstract: A hair covering which comprises a woven or nonwoven substrate comprising synthetic or natural materials, which are impregnated, or coated, or both, with a mutable dye is described.

Abstract: A cleaning wipe comprising a nonwoven fabric wherein the nonwoven fabric is impregnated with a cleaning composition.

Abstract: Silk clothes for protecting affected parts (incised wound, burn, tumor, bedsore, etc.) which also contribute to the prevention of suppurating. These clothes are composed of a knitted woven silk fabric or non-woven silk fabric (silk floss, etc.) containing either Sasa veitchii or a parabenzoic acid ester or both of the same and being adhered to a non-woven fabric made of cellulose, etc.

Abstract: A fire resistant fabric material comprising a substrate having an ionic charge which is coated with a coating having essentially the same ionic charge. The coating consists essentially of a filler material comprising clay and a binder material. The substrate is preferably fiberglass, the filler material may further comprise at least one additional filler selected from the group consisting of decabromodiphenyloxide, antimony trioxide, fly ash, charged calcium carbonate, mica, glass microspheres and ceramic microspheres and mixtures thereof and the binder material is preferably acrylic latex.

Abstract: Compositions for use in inhibiting the production of exoproteins from Gram positive bacteria, such as harmful proteins produced by Staphylococcus species, are described. The compositions are particularly useful for inhibiting the production of TSST-1, alpha-toxin and/or enterotoxins A, B and C from S. aureus bacteria. The compositions include alkyl polyglycoside and a pharmaceutically acceptable carrier. The alkyl polyglycoside typically has an HLB of at least 10 and/or an average number of carbon atoms in the alkyl chain of 8 to 12.

Abstract: A floor cleaning sheet (1) impregnated with an aqueous detergent is used as attached to a cleaning part (11) of a cleaning tool (10) having a handle (12) of stick form connected to the cleaning part (11). The surface layer of the floor cleaning sheet (1) which is to be brought into contact with a floor comprises nonwoven fabric formed by fiber entanglement of a fiber web and has a static friction resistance of 900 to 2500 cN against #1200-grit sandpaper.

Abstract: A packaged pre-moistened wet wipe comprising a web of nonwoven fibers bonded with a water soluble and/or dispersible polymeric binder in contact with an aqueous composition which is substantially free of boric acid and contains a sufficient amount of a water-binding compound, which preferably is a salt of an organic or inorganic acid, to prevent the dissolution/redispersion of the water soluble/dispersible components of the binder composition while imbuing the nonwoven with a wet tensile strength that is at least as great as that afforded by a 4 wt % boric acid solution.

Abstract: A treated substrate with improved availability of a beneficial component for transfer to a target surface and methods for making the same are described. The substrate has a contacting surface with a beneficial component that is transferred from the contacting surface to a target surface during use of the article. The beneficial component is applied to the article in such a way as to “Top-Bias” the component on or near the contacting surface of the article.

Abstract: A deodorant fibrous material contains (1) as a first deodorant material, at least one deodorant component selected from inorganic type and polyorganic acid, ester or salt type components, (2) as a second deodorant material, at least one hydrazine compound and (3) a synthetic resin binder. The deodorant fibrous material can be produced by applying to a fibrous material by a padding or coating method, a liquid composition containing the above components (1)-(3), followed by subsequent heat treatment.

Abstract: A coated filter bag for use in cold or hot drinks, in particular, a novel method for administration of pharmaceutical actives, supplemental nutrients, genetically derived materials, or other beneficial agents using a coated filter bag that includes at least one agent that solubilizes when in contact with liquid and is dispersed in the proper dosage amount into the liquid for oral consumption.

Abstract: Cyclodextrins and other ecapsulating oligosaccharides can be bound to fibrous and/or polysaccharidic carriers by ionic bonds. The ionic bonds can be produced by introducing cationic or anionic groups into the cyclodextrins, and where appropriate, by introducing oppositely charged groups in the carrier material. The products can be used for odor control in the fibrous material.

Abstract: A wet cleaning sheet 1 comprises an aqueous liquid-retaining layer 4 having an aqueous liquid-containing polymer and a chemical-containing layer 2 or 9 containing a chemical which causes the polymer to release the aqueous liquid. The aqueous liquid-retaining layer 4 and the chemical-containing layer 2 or 9 are formed and/or arranged in such a manner that they are kept out of substantial contact under no load applied but brought into contact with each other with a prescribed load applied whereby the aqueous liquid is gradually released from the polymer by the action of the chemical.

Abstract: A covering for soft furnishing is impregnated with an insecticide, such as permethrin. The concentration of permethrin is sufficient to kill house dust mites and deter larger insects such as fleas and ticks. The insecticide is released from the covering over an operational period so as to encourage the absorption of the insecticide into surrounding soft furnishings. The covering is manufactured from machined fabric, such as knitted voile, having interstices sufficiently small to reduce the rate of insecticide release over the operational period.

Abstract: The invention relates to microbicidal wallcoverings and methods of making the same.

Abstract: Tissue engineering scaffolds comprising collagen or a collagen-like peptides incorporated within or between polymeric fibers and methods for their production are provided.

Abstract: A protective glove includes a coating of dehydrated material on its inside surface. The dehydrated material, in contact with perspiration from a hand wearing the glove, soothes the hand. Some methods of placing the coating onto the inside surface of the glove include spraying or dipping with a solution that includes Aloe Vera.

Abstract: This invention relates to antimicrobial polyester-containing articles and methodology for the preparation of antimicrobial polyester-containing articles utilizing chitosan and chitosan-metal complexes as the antimicrobial agent.

Abstract: A cosmetic towelette is provided which includes a water-insoluble substrate and a fluid cosmetic composition impregnated into the substrate. The composition has a viscosity ranging from 0 cps to about 100 cps. The composition includes a water phase, a sunscreen phase and a surfactant system. The sunscreen phase is immiscible with the water phase and contains at least 25% organic sunscreen agent. Towelettes impregnated with the composition impart an effective SPF to the skin when applied thereto.

Abstract: A novel article and method are disclosed including a heated disposable wash cloth. In one aspect, the invention provides a novel article and method including a wash cloth structure having from about 75 to about 89 weight percent of a thermoretentive oil-in-water emulsion. In one aspect, the fiber content contains a 50/50 ratio of rayon and polyester compositionally part of the wash cloth substrate structure. The novel article and method of the present invention are effective in maintaining extended warmth on the skin and providing moisturization of the skin surface for up to 6 hours after washing.

Abstract: An article is provided for cleansing surfaces, the article includes a curvilinear pouch formed from a plurality of walls, at least one of the walls being water permeable, and at least one of the walls being formed from at least one web of non-woven entangled fibers, the fibers being entangled in a direction perpendicular to a major longitudinal axis of the web. An effervescent cleanser composition which is an anhydrous dry solid activatable by water to generated gases is held within the pouch, and upon generation of gases the pouch walls billow outwardly. Orientation of the entangled fibers in the direction of the minor axis minimizes puckering of the article in use.

Abstract: A drug carrier, and methods of making and using the same. The drug carrier includes a scaffold including a plurality of layers and a fiber system interconnecting the plurality of layers, wherein the layers define internal and superficial positions for the scaffold; and a drug releasably engaged with the scaffold according to a controlled release profile, wherein the drug is releasably engaged at at least one of the internal or superficial positions. Optionally, the scaffold is a three-dimensional fiber scaffold including at least three systems of fibers, wherein two of the three fiber systems define the plurality of layers, wherein one of the at least three fiber systems interconnects the plurality of layers, and wherein the three dimensions of the scaffold define internal and superficial positions within the scaffold. The drug carrier design is versatile, such that drug release profiles can be customized for a given application.

Abstract: An insecticide-impregnated fabric that remains sufficiently effective at killing and repelling disease vector insects after repeated washings with detergent and water is described. The fabric is impregnated with an insecticide composition containing an insecticide, a cyclodextrin, and a binding agent. The resulting fabric is useful for providing personal protection against disease-carrying insect vectors, particularly when assembled as a bednet in regions of the world where malaria is prevalent, and will remain effective for a longer period of time before re-impregnation is necessary.

Abstract: Method for arresting local bleedings by topical use of FVIIa and a hemostatic composition containing FVIIa.

Abstract: A dermatological delivery system comprising a topically acceptable, inert support selected from the group consisting of cotton, rayon, polyester, polypropylene, wood pulp, mohair, nylon fleece, and neoprene foam, or combination thereof, impregnated with an about 0.1% to about 2% solution of metronidazole; the solution having a major solvent component comprising water, ethanol or a mixture of water and ethanol, the support being operable to permit application of the solution to the skin.

Abstract: Provided herein are moist towelettes useful for cleansing, among other things, hard surfaces and human skin. The moist towelettes of the invention comprise a towelette portion which is moistened with a liquid composition of matter wherein the liquid composition includes an alkylene carbonate as one of its components. According to one preferred form of the invention, the liquid composition from which the towelettes are made moist are alcohol-free. In another embodiment, a substantial portion of the alcohol in a given formulation is replaced with an alkylene carbonate component. Preferred alkylene carbonate components include propylene carbonate, butylene carbonate, and glycerine carbonate.

Abstract: The invention consists of a care-system for the cosmetic treatment of skin through layering of a care-material-containing surface element on the skin portions to be treated, at least inclusive of a textile surface, which is compressed, essentially liquid-free, as well as a liquid, wherein the textile product and/or the liquid care-material are exhibited and the textile product for absorption of liquid is expandable to a care material-containing surface element. The care system of the invention demonstrates that through a simple and hygienic application that it can be applied with little time consumption.

Abstract: The present invention relates to substrates such as wipe articles for use in combination with substances, such as ingredients and formulations, for delivery to the human body or for use on inanimate surfaces such as those found in households and/or workplace. The substrate utilizes shear responsive micropockets that store substances, and controllably release said substances when shear forces are applied thereto, while in contact with the target surface. Shear responsive micropockets are fine scale three-dimensional compartments in the surface of the substrate such that applying shear forces along the surface of said substrate while said substrate is in contact with said target surface, said shear forces cause walls of said micropockets to substantially deform, and release said substance, to said target surface.

Abstract: A novel device for the delivery of one or more active agents to a subject is disclosed. The device includes a water-soluble or water-dispersible polymeric carrier, an adhesive, one or more active agents and a support layer. Methods of manufacturing and use of said device also are disclosed.

Abstract: Biodegradable and/or bioabsorable fibrous articles and methods for using the articles in medical applications are disclosed. The biodegradable and/or bioabsorable fibrous articles, which are formed by elctrospinning fibers of biodegradable and/or bioabsorbable fiberizable material, comprise a composite (or asymmetric composite) of different biodegradable and/or bioabsorbable fibers. Articles having specific medical uses include an adhesion-reducing barrier and a controlled delivery system. The methods include methods for reducing surgical adhesions, controlled delivery of a medicinal agent and providing controlled tissue healing.

Abstract: This invention relates to antimicrobial fabrics which are treated with a specific durable and regenerable halamine/chlorine system and methods of removing residual active chlorine from the target textile surface without reducing the antimicrobial activity of the textile. Such methods comprise contacting an amine-treated fabric first with a halogen-based bleach (or other halogenated liquid) to produce halamines at the fabric surface, and subsequently washing the resultant halogenated fabric with a reducing agent which removes the residual, unbonded halogen (such as chlorine) from the fabric surface but does not, surprisingly, remove the halamine halogen. The remaining halamine halogen thus provides the desired antimicrobial activity.

Abstract: An elongated biopolymer structure containing fibrin, and having at least one portion stretched in at least one stretching direction. In addition to fibrin, the elongated structure can also contain biopolymers such as fibrinogen, polysaccharides and collagen. Also provided are processes for making the structure as well as articles comprising the structure, having various shapes. The articles are useful for directing wound healing and cell growth, especially in the field of tissue engineering.

Abstract: Polyurethane elastomer yams (particularly spandex) containing certain silver-based antimicrobial formulations therein are provided. This invention relates to polyurethane elastomer yams (particularly spandex) containing certain silver-based antimicrobial formulations therein. Such formulations comprise antimicrobial compounds, such as, preferably, triclosan and/or silver-containing ion-exchange resins, such as zirconium phosphate, glass, and/or zeolite compounds. The inventive spandex yarns exhibit excellent antimicrobial qualities as well as surprisingly good anti-tack/frictional characteristics. As a result, antimicrobial spandex yams are provided which exhibit ease in processing, particularly in further knitting, weaving, etc., to produce fabrics therefrom. Such fabrics are also encompassed within this invention.

Abstract: A class of water insoluble iodophors comprising complexes of iodine with various nylons such as nylon-4,6, nylon-6, nylon-6,6 or other polyamides is disclosed. These nylons complexed with iodine can be made in various forms such as powders, pellets, molded objects, granules, films, monofilaments, and either non-woven or woven fabrics. These nylon based iodophors and other water insoluble iodophors herein disclosed can find product applications in the fields of air treatment, water treatment, public hygiene and medicine.

Abstract: Multi-layer substrates for a premoistened wipe capable of controlled fluid release comprise a reservoir layer and a surface contact layer, wherein the reservoir and surface contact layers have certain blends of hydrophilic and hydrophobic fibers, as well as certain basis weights. Premoistened wipes for treating and/or cleaning a surface comprise the multi-layer substrate and a liquid composition impregnated into the multi-layer substrate, wherein the liquid composition comprises a surfactant system and/or a solvent system. Methods of treating and/or cleaning a surface comprise the step of contacting the surface with a premoistened wipe of the present invention.

Abstract: A wound dressing and method for treating a wound with a wound dressing are provided. In particular, the wound dressing contains a fibrous component, for example, made from silk fibers or wool fibers for attracting and capturing proteases from a wound site that may interfere with the healing of the wound.

Abstract: A package containing at least one soft fibrous wipe laminate; the wipe laminate comprising a nonwoven wipe layer formed from a nonwoven web comprised predominantly of thermoplastic polymer, copolymer or blend fibers; and a backing layer bonded to the wipe layer where the nonwoven fibrous web has bonded regions and unbonded regions the unbonded region forming the arcuate mounds.

Abstract: A package containing at least one soft fibrous wipe laminate; the wipe laminate comprising a nonwoven wipe layer formed from a nonwoven web comprised predominantly of thermoplastic polymer, copolymer or blend fibers; and a backing layer bonded to the wipe layer where the nonwoven fibrous web has bonded regions and unbonded regions the unbonded region forming the arcuate mounds.

Abstract: Disclosed are methods for securing the intersection formed by two or more crossed strands. The intersection defines at least two sections. The practice of the disclosed methods includes bending a securing material, such as a suture or other suitably biocompatible material, through at least two of the sections formed by the intersection, and joining them to secure the intersection. Also disclosed are devices formed by using securing material to secure the intersection of crossed strands of a medical device, such as a woven stent. The secured intersection or intersections of the resultant device enhance the structural integrity of the device, and may serve to eliminate the possible unwinding or release of unsecured, or free, strand ends. Radiopaque materials, in addition to polymers, may be used as securing material.

Abstract: A method for cell selection is disclosed. The method uses an azlactone-functional support, which is derivatized with and covalently coupled to a substance that is biologically active with a desired type of whole cell. The method allows the whole cells in the mixture to interact with and bind to the coupled biologically active substance, after which a remainder of the mixture is removed from the support. Optionally, one can elute the bound whole cells from the coupled biologically active substance to produce a purified collection of the whole cells.

Abstract: The invention relates to an acarcid-resistant carpet wherein an acaracidal compound is fixed at or near the base of the carpet tufts over which an adhesive layer is applied to the carpet tufts into a primary backing material. The invention further relates to methods of making such carpet.

Abstract: The present invention relates to materials which absorb human body odor, or odors associated with humans, prevent production of human body odors, or odors associated with humans, and prevent the detection of human body odors, and odors associated with humans, by animals, The materials comprise polyester fibers and antimicrobial acetate fibers. The materials can be made into, for example, twill, fleece, jerseys and hunting garments, apparel, protective garments and hunting accessories made therefrom.

Abstract: An apparatus comprising a substrate comprising an absorbent material and a composition contained within the substrate, the composition comprising at least an antibacterial agent and a spermicidal agent.

Abstract: A treatment device may comprise a cover defining a cavity, wherein the cavity is configured to receive a part of a body. The cover may comprise at least one sheet having a composite structure. The composite structure may comprise at least two layers and at least one adhesive matrix situated between the two layers. At least one of the two layers may be permeable to a solvent, and the two layers may be permanently bonded to the adhesive matrix. The adhesive matrix may contain at least one active agent that is soluble in the solvent. When the active agent is dissolved in the solvent, the active agent may be released from at least one side of the cover.

Abstract: The present invention relates to absorbent articles including non-aqueous compositions for protecting the barrier function of the skin. The compositions can be applied to the bodyfacing surfaces of absorbent articles so that the compositions come into contact with the skin. The compositions of the invention have improved stability on the bodyfacing surfaces after processing. The compositions of the invention provide several benefits including prevention and alleviation of skin irritations associated with the use of absorbent articles. The compositions can include emollients, viscosity enhancers and extracted botanical actives.

Abstract: The present invention relates to the use of 4-hydroxyisothiazole compounds as antimicrobially active substances, certain new 4-hydroxyisothiazole compounds and a process for their preparation.