Abstract: The present invention relates to a rational hive structure (1) comprising a nest comb box (2) delimiting a brood chamber for bees; a top cover (4) located in an upper portion of the hive structure to close an upper access to the hive structure; a lower closure element (5) located in a lower portion of the hive structure to close a bottom access to the hive structure; and a plurality of comb frames (6) in the form of substantially flat bodies extending in a main plane. Each comb frame includes peripheral element or bars (7) delimiting an inner comb area (8), wherein the inner comb area (8) has an overall dimension of at least 15 dm2.