Comprising Or Including Means For Cooling Patents (Class 494/14)
  • Patent number: 7591775
    Abstract: A centrifugal separator includes: a sample line; and a rotating apparatus portion including a rotor that has a rotor chamber. The centrifugal separator centrifugally separates a sample by supplying the sample from the sample line into the rotor and driving to rotate the rotor in the rotor chamber and discharges the centrifugally separated sample from the rotor via the sample line. The centrifugal separator includes: a sterilizing apparatus for sterilizing at least a portion with which the sample is brought into contact by making a sterilizing fluid flow through the sample line.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: September 22, 2009
    Assignee: Hitachi Koki Co., Ltd.
    Inventors: Yoshinori Tobita, Masaharu Aizawa, Katsunori Akatsu, Tomohiro Koizumi
  • Publication number: 20090197752
    Abstract: A continuous flow centrifuge system is provided. The system includes a rotor, a stator, a stator housing, upper and lower bearing plates, upper and lower bearings, first and second snap rings, and lip seal. The upper bearing rotatably secures a shaft of the rotor in the upper bearing plate. The first snap ring secures the upper bearing to the rotor shaft. The lip seal is over the upper bearing and forms a rotatable seal with the upper bearing plate. The second snap ring secures the lip seal to an inner diameter of the upper bearing plate. The upper and lower bearing plates are secured to the stator housing so that the rotor is operatively aligned with the stator.
    Type: Application
    Filed: December 18, 2008
    Publication date: August 6, 2009
    Inventors: Kurt Spiegel, Sorin Weissman, Bill Lepse, Blaine J. Marsh
  • Patent number: 7485085
    Abstract: The present application relates to an apparatus and method for heat transfer for thermal cycling.
    Type: Grant
    Filed: January 23, 2004
    Date of Patent: February 3, 2009
    Assignee: Applied Biosystems Inc.
    Inventors: Janice G. Shigeura, legal representative, John Shigeura
  • Publication number: 20080300124
    Abstract: According to an aspect of the present invention, there is provided a centrifuge in which a steam sterilization of a sample flow passage is performed, the centrifuge including: a rotor configured to centrifuging a liquid sample; a drive portion that drives and rotates the rotor; a chamber that accommodates the rotor therein, the chamber having a first and a second penetration holes provided on an upper and a bottom portions thereof, respectively; and a first and a second valves disposed on the first and the second penetration holes, respectively; wherein a cooling gas is introduced through one of the first and the second penetration holes and discharged through the other to cool a periphery of the rotor before or after execution of a centrifuging operation of the liquid sample.
    Type: Application
    Filed: May 30, 2008
    Publication date: December 4, 2008
    Inventors: Katsunori AKATSU, Masaharu Aizawa, Tatsuya Konno
  • Patent number: 7407473
    Abstract: A method and apparatus is disclosed for setting energy saver sleep modes for use in a centrifuge systems. The centrifuge system contains an energy saver touch screen control which can be either manually set or automatically set to turn the centrifuge on or off at predetermined times. This allows the centrifuge system to be readily available to a user, resulting in lower wear and tear being placed on the major systems of the centrifuge and waste less energy.
    Type: Grant
    Filed: April 9, 2003
    Date of Patent: August 5, 2008
    Assignee: Thermo Fisher Scientific (Asheville) LLC
    Inventor: Vincent Saviano
  • Patent number: 7371205
    Abstract: A rotor assembly for centrifuging reaction vessels containing reaction mixtures in a device for asymmetric heating and cooling of reaction mixtures during centrifugation. The rotor contains at least one fan blade used to force ambient gas to pass the reaction mixture. Also provided is a device for asymmetric heating and cooling of reaction mixtures during centrifugation.
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: May 13, 2008
    Assignee: Alphahelix Molecular Diagnostics AB
    Inventors: Leif Andersson, Mats Malmqvist
  • Patent number: 7204795
    Abstract: The invention relates to a deviation ring for paste comprising an annular rebound wall (2) for a self-distributing centrifuge (1). The invention also relates to a corresponding self-distributing centrifuge (1). In the deviation ring, the angle of incidence ? of the tangents of the rebound wall (2) of the deviation ring (4), opposite the distribution slit (3) of the centrifuge (1), in relation to the horizontal, is between 3 and 60° over the entire opening width of the distribution slit (3).
    Type: Grant
    Filed: July 8, 2002
    Date of Patent: April 17, 2007
    Assignee: Westfalia Separator AG
    Inventors: Ernst-Ulrich Himmen, Markus Longerich, Jürgen Scholz, Detlef Freyer, Ulrich Esser
  • Patent number: 7192394
    Abstract: The present invention relates to an air-cooled centrifuge comprising a rotor driven around a rotation axis by a motor and a cooling channel, which surrounds one wall of the rotor, wherein the cooling channel is provided for the air transportable in the cooling channel with an outlet opening, through which air can flow out from the centrifuge, and the outlet opening comprises a first wall, which starts at the outer periphery of the cooling channel and continues in such a way that it has an increasing distance from the rotation axis of the rotor with the simultaneously increasing rotation angle around the rotation axis of the rotor, wherein the outlet opening comprises a second wall, which starts at the outer periphery of the cooling channel and continues in such a way that it has an increasing distance from the rotation axis of the rotor with the simultaneously increasing rotation angle around the rotation axis of the rotor, so that the second wall extends as a straight line or has a curved contour, whose cent
    Type: Grant
    Filed: December 27, 2005
    Date of Patent: March 20, 2007
    Assignee: Thermo Fisher Scientific Inc.
    Inventor: Andreas Karl
  • Patent number: 7081082
    Abstract: Method for separating blood plasma particles from a blood plasma suspension in a self-discharging centrifuge having two or more discharge slits and axially stacked baffle plates, in which the blood plasma particles are separated from the liquid phase by centrifuging and removal of the liquid phase, suctioning off liquid remaining in the drum after separation of the blood plasma particles and discharging the sediment of solid blood plasma particles from the drum by centrifugal force into a collecting container underneath the drum, the drum and the blood plasma sediment being cooled during one or more of the process steps.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: July 25, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jürgen Scholz, Markus Longerich, Ernst-Ulrich Himmen, Ulrich Esser, Rajesh Sharma, Anshuman V. Patwardhan
  • Patent number: 6953424
    Abstract: In a centrifugal separator, a temperature sensor is provided in contact with a vibration isolation rubber that elastically supports an induction motor to a motor base. A Peltier element for heating/cooling the vibration isolation rubber is provided in contact with the vibration isolation rubber. The temperature sensor and the Peltier element is connected to a controller. Based on a detected temperature input from the temperature sensor, the controller controls heat generation or cooling effected by the Peltier element, thereby maintaining an optimum temperature of the vibration isolation rubber to maintain its damping characteristics.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: October 11, 2005
    Assignee: Hitachi Koki Co., Ltd.
    Inventors: Shoji Kusumoto, Hiroyuki Takahashi
  • Patent number: 6866621
    Abstract: A laboratory with a rotor driven by a centrifuge electric motor and a cooling unit driven by an electrical cooling motor, wherein the centrifuge motor is formed as a frequency-controlled induction motor fed from a frequency converter controlled by a control unit and having a centrifuge inverted rectifier that feeds the centrifuge motor and is connected to a d.c. source fed from a mains power rectifier, characterized in that the cooling motor is formed as a frequency-controlled induction motor, and that the frequency converter has a further cooling inverted rectifier connected to the d.c. source parallel to the centrifuge inverted rectifier for feeding the cooling motor.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: March 15, 2005
    Assignee: Eppendorf AG
    Inventors: Heiko Müller, Horst Kache
  • Publication number: 20040176233
    Abstract: The invention relates to a deviation ring for paste comprising an annular rebound wall (2) for a self-distributing centrifuge (1). The invention also relates to a corresponding self-distributing centrifuge (1). In the deviation ring, the angle of incidence ? of the tangents of the rebound wall (2) of the deviation ring (4), opposite the distribution slit (3) of the centrifuge (1), in relation to the horizontal, is between 3 and 60° over the entire opening width of the distribution slit (3).
    Type: Application
    Filed: December 30, 2003
    Publication date: September 9, 2004
    Inventors: Ernst-Ulrich Himmen, Markus Longerich, Jurgen Scholz, Detlef Freyer, Ulrich Esser
  • Patent number: 6783993
    Abstract: The efficient temperation of a sample is achieved when the sample is subjected to centrifugation simultaneously wish heating and optionally also cooling. This is achieved in a device comprising at least a rotor (1) for holding reaction vessels (2), a motor (3), connected to the rotor, a processor (4) for controlling the speed of the rotor, and elements (5 and 6) for heating and cooling the contents of the reaction vessels, wherein the elements (6) for heating cover the apices of the reaction vessels for at least part of the rotational path of the vessels and that the elements for heating operate at a temperature significantly higher than the meeting temperature of the reaction vessels. The invention further relates to a method for performing chemical reactions and in particular a method for performing biochemical reactions involving thermocycling, for example PCR-reactions.
    Type: Grant
    Filed: September 25, 2001
    Date of Patent: August 31, 2004
    Assignee: Alphahelix AB
    Inventor: Mats Malmquist
  • Publication number: 20040142807
    Abstract: A two-tube centrifuge separates light material and heavy material from an input mixture. A hollow drive shaft rotates a central body member about an axis of rotation. Two hollow arm assemblies, each having circular cross-section, are mounted on diametrically opposite sides of the central body. Each arm assembly includes an outer housing tube, an intermediate tube, and an inner tube that is longer than the intermediate tube. An end cap having a removable plug is mounted on the outer end of the housing-tube of each arm assembly. The inner ends of all three tubes are mechanically interlocked in a manner to cantilever mount the inner and intermediate tubes to the central-body with their outer ends spaced from the internal surface of the end cap. An input-mixture path extends through the hollow drive shaft, through the central-body, and into a cylindrical space between the inner and intermediate tubes of each arm assembly.
    Type: Application
    Filed: November 26, 2003
    Publication date: July 22, 2004
    Inventors: Paul J. Cornay, Ernest Peter Tovani, Gary Matzen
  • Publication number: 20040023778
    Abstract: In a centrifugal separator, a temperature sensor is provided in contact with a vibration isolation rubber that elastically supports an induction motor to a motor base. A Peltier element for heating/cooling the vibration isolation rubber is provided in contact with the vibration isolation rubber. The temperature sensor and the Peltier element is connected to a controller. Based on a detected temperature input from the temperature sensor, the controller controls heat generation or cooling effected by the Peltier element, thereby maintaining an optimum temperature of the vibration isolation rubber to maintain its damping characteristics.
    Type: Application
    Filed: July 30, 2003
    Publication date: February 5, 2004
    Applicant: HITACHI KOKI CO., LTD.
    Inventors: Shoji Kusumoto, Hiroyuki Takahashi
  • Patent number: 6605028
    Abstract: A centrifuge system with a temperature control system for controlling the temperature of fractions removed or output from the centrifuge to a collection chamber. In one embodiment, the centrifuge system provides an integral heater element operable by a temperature controller to control the temperature of the collection chamber or dispenser assembly. A temperature sensor is provided to allow the temperature controller to accurately monitor the temperature of the fraction held in chambers or syringes in the dispenser assembly. In a more particular embodiment, the centrifuge system is utilized to separate and extract platelets from blood samples. The heater element is positioned adjacent collection syringes in the dispenser assembly and selectively operated to maintain the temperature of the platelets in the collection syringes within an activation temperature range to activate the platelets and facilitate creation of autologous platelet gel.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: August 12, 2003
    Assignee: Medtronic, Inc.
    Inventor: Victor D. Dolecek
  • Patent number: 6593143
    Abstract: A coaxial-drive centrifuge provides for contactless regulation of sample temperature. The sample is contained in a multi-station chemical-processing circuit that has a metal receptor at each station. On demand, a stationary inductor induces eddy currents in the receptor as it spins by. Dissipation of the eddy current heats the receptor and the surrounding sample. The receptor has a thermal sensor that provides an optical indication of the sample temperature. A stationary contactless reader reads the optical indication. A controller activates the inductor when the reading indicates an actual temperature below a predetermined target temperature. When heating is required, the inductor is pulsed as the receptor is aligned with a gap in the inductor. The chemical-processing circuit is designed for a specific series of chemical reactions, in this case, a polymerase chain reaction (PCR) is implement as an iterated series of three steps.
    Type: Grant
    Filed: July 11, 2000
    Date of Patent: July 15, 2003
    Assignee: Agilent Technologies, Inc.
    Inventor: Gary B. Gordon
  • Publication number: 20020147097
    Abstract: A centrifuge system with a temperature control system for controlling the temperature of fractions removed or output from the centrifuge to a collection chamber. In one embodiment, the centrifuge system provides an integral heater element operable by a temperature controller to control the temperature of the collection chamber or dispenser assembly. A temperature sensor is provided to allow the temperature controller to accurately monitor the temperature of the fraction held in chambers or syringes in the dispenser assembly. In a more particular embodiment, the centrifuge system is utilized to separate and extract platelets from blood samples. The heater element is positioned adjacent collection syringes in the dispenser assembly and selectively operated to maintain the temperature of the platelets in the collection syringes within an activation temperature range to activate the platelets and facilitate creation of autologous platelet gel.
    Type: Application
    Filed: April 9, 2001
    Publication date: October 10, 2002
    Inventor: Victor D. Dolecek
  • Patent number: 6416454
    Abstract: Separation performance in sedimenting centrifuges, particularly generally cylindrical sedimenting centrifuges, and most particularly imperforate basket centrifuges, is controlled and enhanced by identifying a level of mixing that will produce improved separation performance and then varying the bowl-to-feed temperature differential and/or the centrifuge design to produce a desired level and type of mixing while reducing the tendency toward undesirable type of flow.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: July 9, 2002
    Assignee: Kendro Laboratory Products, Inc.
    Inventors: Stephen B. Kessler, Ascher H. Shapiro, William M. Cox
  • Patent number: 6390964
    Abstract: The invention relates to a centrifuge and to a method for operating the centrifuge. The centrifuge comprises a centrifugal drum, an inflow tube leading into the centrifugal drum for feeding a centrifugal material into the centrifugal drum, and a valve mechanism, which can be acted upon by control fluid, for cooling the centrifugal drum. The control fluid is cooled such that it acts as a cooling medium.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: May 21, 2002
    Assignee: Westfalia Separator AG
    Inventor: Wilfried Mackel
  • Publication number: 20020032111
    Abstract: A two-tube centrifuge separates light material and heavy material from an input mixture. A hollow drive shaft rotates a central body member about an axis of rotation. Two hollow arm assemblies, each having circular cross-section, are mounted on diametrically opposite sides of the central body. Each arm assembly includes an outer housing tube, an intermediate tube, and an inner tube that is longer than the intermediate tube. An end cap having a removable plug is mounted on the outer end of the housing-tube of each arm assembly. The inner ends of all three tubes are mechanically interlocked in a manner to cantilever mount the inner and intermediate tubes to the central-body with their outer ends spaced from the internal surface of the end cap. An input-mixture path extends through the hollow drive shaft, through the central-body, and into a cylindrical space between the inner and intermediate tubes of each arm assembly.
    Type: Application
    Filed: April 6, 2001
    Publication date: March 14, 2002
    Inventors: Paul J. Cornay, Ernest Peter Tovani, Gary Matzen
  • Patent number: 6334841
    Abstract: This centrifuge includes a chamber (5), a rotor (6) arranged therein, a device (8) for driving the rotation of the rotor, and a device (11) for cooling the atmosphere of the chamber. The device for cooling the atmosphere of the chamber includes a Ranque vortex tube (30), a cold outlet (33) which is connected to one inlet (66) of the chamber. The centrifuge includes a pressurized-gas supply circuit which is connected to an inlet (32) of the Ranque vortex tube and which is intended to be connected to a source (49) of pressurized gas. Application is to the centrifuging of biological products.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: January 1, 2002
    Assignee: Jouan
    Inventor: Jean Claude Letourneur
  • Patent number: 6241650
    Abstract: This centrifuge includes a chamber (5), a rotor (6) arranged therein, and a device (8) for driving the rotation of the rotor. The device (8) for driving the rotation of the rotor is a pneumatic drive device. The centrifuge includes a circuit for supplying the pneumatic drive device with pressurized gas intended to be connected to a source (49) of pressurized gas. The centrifuge further includes a gas-purification unit (10), one inlet of this unit being connected to an outlet (64) for drawing gas from the chamber and one outlet of this unit being connected to a suction device (21) controlled by the pressurized gas supplied to the pneumatic device (8) for driving the rotor. Application is to the centrifuging of products liable to release dangerous substances, for example toxic or explosive substances.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: June 5, 2001
    Assignee: Jouan
    Inventor: Jeau Claude Letourneur
  • Patent number: 6228016
    Abstract: A simple but still effective sealing device to separate two openings (4, 5), which are arranged at a distance from each other in the outer casing (3) of a shaft suspension unit (1), which supports a shaft (2) of a centrifugal separator in a bearing (8, 9), the shaft extending axially through at least one opening (4) into a space surrounding the shaft (2) in the outer casing (3). The sealing device is provided with sealing elements (12, 13), one connected to the outer casing (3) and one connected to the shaft (2), which surround the shaft (2) and divide the space in two departments (15, 16) connected to one opening each (4, 5, respectively). The sealing elements form between themselves a narrow gap (14) surrounding the shaft (2), which prevents the flow of gas between the departments (15, 16).
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: May 8, 2001
    Assignee: Alfa Laval AB
    Inventors: Aksel Kristensen, Sven-Åke Nilsson, Jouko Pitkämäki, Carl Peder Öhlander, Robert Sandblom
  • Patent number: 6196961
    Abstract: An automatic centrifugal machine comprises a handling apparatus for shifting a test specimen from a predetermined position, a rotor equipped with a bucket accommodating the test specimen, a drive motor for rotating the rotor, a chamber surrounding the rotor, and a refrigerator for cooling the chamber, and the automatic centrifugal machine has a height equal to or less than 1,450 mm. A conveyor line, conveying the test specimen, has a height in a range from 750 mm to 850 mm. The handling apparatus of the test specimen is formed by a link arm mechanism including first and second sliders, first and second arms, and a manipulator hand.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: March 6, 2001
    Assignee: Hitachi Koki Co., Ltd.
    Inventors: Hideki Hoshiba, Masahiro Inaniwa, Hidetaka Osawa, Hiroshi Hayasaka
  • Patent number: 6117063
    Abstract: The invention refers to a device and a method for cooling a bearing of a centrifugal separator. Through a portion (11, 21) adjacent to the bearing extends at least one channel (15, 23), which is arranged to receive a flow of a cooling medium and comprises at least two successive channel portions (23) and at least one connecting portion (24) provided between successive channel portions. The connecting portion (24) is arranged to provide such a mixing of the cooling medium in the flow through the channel that the flow has an essentially uniform velocity profile immediately after the connecting portion.
    Type: Grant
    Filed: June 12, 1998
    Date of Patent: September 12, 2000
    Assignee: Alfa Laval AB
    Inventors: Stefan Szepessy, Jouko Juhani Pitkamaki
  • Patent number: 6068586
    Abstract: A laboratory centrifuge has a housing which can be closed by a casing cover and having in the housing a rotor chamber which contains a motor-driven vertical-axis rotor to accept test tubes. During operation, the test tubes are warmed by friction. To cool the centrifuge, cooling air is pulled in through openings in the lower side of the housing and upward into the rotor chamber by the fan action created by the rotation of the rotor. The air is guided out of the rotor chamber through an air exit in a direction of flow tangential to the perimeter of the rotor in a manner that ensures low turbulence and, thus, low noise. In particular, a slit-like air exit opening is arranged between the casing cover and the top side of the housing.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: May 30, 2000
    Assignee: Kendro Laboratory Products GmbH
    Inventors: Michael Koch, Detlev Demmig, Rudiger Uhlendorf, Sebastian Reich
  • Patent number: 6063019
    Abstract: A centrifuge including a non-rotatable containment vessel, a rotatable centrifuge tube within said vessel, an inlet assembly for dirty gas, an outlet assembly for clean gas, and an outlet assembly for dirty gas, said inlet assembly for the dirty gas and said outlet assembly for the dirty gas being located in close mutual proximity and at or towards one end of the centrifuge tube, the outlet for the clean gas being located at the opposite end of the centrufuge tube, the flow of gas entering the centrifuge tube being reversed within the centrifuge tube so as to increase the residence time of the dirty gas within said centrifuge tube. The centrifuge tube is supported on spaced foil bearings located at predetermined spacings relative to each other and to the ends and center of the centfrifuge tube.
    Type: Grant
    Filed: December 3, 1997
    Date of Patent: May 16, 2000
    Inventor: Brian Wade
  • Patent number: 5904836
    Abstract: High-vacuum oil refinery systems and process are disclosed in this invention. The systems and process enables to carry out vaporization and distillation of oils under the condition of 1-10.sup.-4 Torr of high vacuum and at the temperature of not higher than 360.degree. C. and thereby removing possibility of thermal cracking while heating to be vaporized and easily produces high quality oil. The vaporized gases are centrifugally separated and liquefied by specific gravity using high-vacuum gas specific gravity centrifugal separators and thereby producing high purity oil of uniform quality. The process also carries out vaporization and distillation of the oil at the temperature of not higher than 360.degree. C. so that the process prevents vaporization of sulfur components of the oil, but simply drains the sulfur components along with the concentrated sludge oil and thereby distilling and desulfurizing the crude or heavy oil at the same time without using expensive conventional desulfurizing process.
    Type: Grant
    Filed: February 1, 1996
    Date of Patent: May 18, 1999
    Assignee: Dae Sung Lee
    Inventors: Dae Sung Lee, Ho Keun Shin
  • Patent number: 5897483
    Abstract: A laboratory centrifuge has a housing which can be closed by a casing cover and having in the housing a rotor chamber which contains a motor-driven vertical-axis rotor to accept test tubes. During operation, the test tubes are warmed by friction. To cool the centrifuge, cooling air is pulled in through openings in the lower side of the housing and upward into the rotor chamber by the fan action created by the rotation of the rotor. The air is guided out of the rotor chamber through an air exit in a direction of flow tangential to the perimeter of the rotor in a manner that ensures low turbulence and, thus, low noise. In particular, a slit-like air exit opening is arranged between the casing cover and the top side of the housing.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: April 27, 1999
    Assignee: Kendro Laboratory Products, GmbH
    Inventors: Michael Koch, Detlev Demmig, Rudiger Uhlendorf, Sebastian Reich
  • Patent number: 5842965
    Abstract: A laboratory centrifuge is known with a centrifuge housing which contains a motor and a rotor connected with the motor through a drive shaft, the motor being held in the motor housing which includes an upper end shield and a lower end shield, and with the motor having a rotor tank arranged above it which has a passage for the drive shaft on the motor side. In order to indicate, starting from here, a laboratory centrifuge which is economical to manufacture and simple to assemble, which can be cooled easily, if necessary, it is proposed that the rotor tank and the upper end shield be made as a single piece.
    Type: Grant
    Filed: November 14, 1996
    Date of Patent: December 1, 1998
    Assignee: Heraeus Instruments GmbH & Co. KG
    Inventors: Heinz-Gerhard Kohn, Rudiger Uhlendorf
  • Patent number: 5772572
    Abstract: A laboratory centrifuge having a housing which can be closed by a casing cover and having in the housing a rotor chamber which contains a motor-driven vertical-axis rotor to accept test tubes is disclosed. During operation, the test tubes are warmed by friction. To cool the centrifuge, cooling air is pulled in through openings in the lower side of the housing and upward into the rotor chamber by the fan action created by the rotation of the rotor. The air is guided out of the rotor chamber through an air exit in a direction of flow tangential to the perimeter of the rotor in a manner that ensures low turbulence and, thus, low noise. In particular, a slit-like air exit opening is arranged between the casing cover and the top side of the housing.
    Type: Grant
    Filed: April 21, 1997
    Date of Patent: June 30, 1998
    Assignee: Heraeus Instruments GmbH & Co. KG
    Inventors: Michael Koch, Detlev Demmig, Rudiger Uhlendorf, Sebastian Reich
  • Patent number: 5724819
    Abstract: A refrigerated centrifuge system. The system includes at least one thermoelectric cooler which is operatively connected to a centrifuge chamber by an egress conduit and an ingress conduit. In one embodiment the egress conduit carries away from the centrifuge to the thermoelectric cooler warm air where it is cooled by the thermoelectric cooler. The cooled air then returns to the centrifuge. In another embodiment the warm air in the centrifuge is first passed through a liquid heat exchanger whereby the warmed air transfers heat to a liquid which then is pumped through an egress conduit to a thermoelectric cooler where the liquid is cooled. The cooled liquid is then pumped back to the liquid heat exchanger through an ingress conduit.
    Type: Grant
    Filed: August 28, 1996
    Date of Patent: March 10, 1998
    Inventors: John W. Boeckel, Michael J. Parisi
  • Patent number: 5653672
    Abstract: A centrifugal separator comprises a rotor 5 capable of accommodating a test sample therein, a cooling container 2 accommodating rotor 5 therein, a thermo-module 7 interposed between cooling container 2 and a radiator 3, and a coil spring 8 interposed between cooling container 2 and radiator 3. By the resilient force acting upward, cooling container 2 is lifted or floated off thermo-module 7 when cooling container 2 is placed on thermo-module 7.
    Type: Grant
    Filed: May 28, 1996
    Date of Patent: August 5, 1997
    Assignee: Hitachi Koki Co., Ltd.
    Inventors: Yoshitaka Niinai, Hiroshi Hayasaka
  • Patent number: 5551241
    Abstract: A thermoelectric cooling design of the type having thermoelectric coolers. Provisions for a centrifuge chamber and improved heat dissipation from the thermoelectric coolers are provided. For improved thermal response, the refrigerated centrifuge chamber is provided with a motor driven fan to drive ambient air horizontally over a plurality of heat sinks mounted horizontally concentric with respect to the rotor of the centrifuge.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 3, 1996
    Inventors: John W. Boeckel, Michael J. Parisi
  • Patent number: 5509881
    Abstract: A method and system of identifying a rotor of a centrifuge employ an approach that uses two tiers of model selection. Firstly, the moment of inertia of a rotor is calculated for a first measured acceleration. The indication of moment of inertia is utilized to disqualify a number of rotor models and to select a subset of models. In a second tier, windage power of the rotor is calculated in a manner that isolates windage from inertial drag. In one embodiment, drive torque is measured with the rotor operated at a high constant speed. Alternatively, windage is calculated using data obtained during a second measured acceleration. The accuracy of the computation is enhanced by taking into account the moment of inertia as one form of resistance to the second acceleration. Based upon the indication of windage power, at least one rotor model within the subset is disqualified. Upon identification of the rotor, the centrifugal process can be maintained at a maximum safe speed.
    Type: Grant
    Filed: July 7, 1994
    Date of Patent: April 23, 1996
    Assignee: Beckman Instruments, Inc.
    Inventor: Thomas D. Sharples
  • Patent number: 5490830
    Abstract: A biohazard centrifuge having an improved air cooling arrangement, wherein a cooling air stream is directed onto and around the rotor chamber of the centrifuge without introducing cooling air thereinto. This results in cooling air being separated from the spinning rotor and reduces the possibility of contamination of the cooling air stream from a leaking sample container. Additionally, further protection to laboratory personnel is afforded by a sealed rotor assembly chamber, and by providing rotor assembly specimen containers or carriers having lids which are easily attached and removed, requiring a simple partial twist to lock the lids into place.
    Type: Grant
    Filed: April 12, 1994
    Date of Patent: February 13, 1996
    Assignee: Global Focus Marketing & Distribution
    Inventors: Charles Lovelady, Bert R. Williams, III
  • Patent number: 5431620
    Abstract: A method and system of determining an operation parameter for a centrifuge includes measuring one or more physical characteristics of a rotor interchangeably supported by a rotor drive. In the preferred embodiment, windage is measured at a first rotational speed and a speed-dependent signal is generated to adjust a vacuum system based upon changes in rotational speed of the rotor. Changes in windage may also be used as a basis for adjusting a refrigeration circuit. Either as an alternative or in addition to monitoring windage, the moment of inertia can be measured and used to adjust adaptive circuitry. For example, the drive circuitry may be adjusted based upon a determination of inertia as the physical characteristic of interest. The method and system isolate inertia and windage as the main forms of resistance to acceleration of the rotor.
    Type: Grant
    Filed: July 7, 1994
    Date of Patent: July 11, 1995
    Assignee: Beckman Instruments, Inc.
    Inventors: Alan L. Schenck, Jin Y. Song
  • Patent number: 5356365
    Abstract: A temperature-controlled centrifuge in which a heat exchanger is attached to the bottom portion of the centrifuge bowl to remove heat from the bowl and materials within the bowl interacting therewith. In one embodiment, a heat exchange plate having a plurality of substantially annular channels is appropriately attached to the bottom of the centrifuge bowl and has a surface which is thus substantially coextensive therewith. Each of these channels are positioned at different radial distances from the central axis of the heat exchange plate and each extends substantially about such axis. An appropriate heat transfer medium may thus be circulated through each of these channels to thereby substantially control a temperature across the entire bottom of the bowl. The heat transfer medium may be provided to each of the channels by a common feed inlet which also allows for the use of flow regulators where appropriate, and the heat transfer medium may also thus be removed from the channels by a common dump line.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: October 18, 1994
    Assignee: Cobe Laboratories, Inc.
    Inventor: Mark J. Brierton
  • Patent number: 5261252
    Abstract: The noise emission from the centrifuge refrigeration system, and in particular, from the condenser fan therein, are minimized by monitoring the time duration during which the refrigeration compressor is asserted and, in accordance with the time duration of compressor assertion, controlling the speed of rotation of the condenser fan.
    Type: Grant
    Filed: October 9, 1992
    Date of Patent: November 16, 1993
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Angelo Peruch
  • Patent number: 4941866
    Abstract: A centrifuge comprises a vacuum chamber (1) accomodating a replaceable rotor (7). The vacuum chamber (1) includes an evaporator (4) connected to a cooling unit (3). A drive (9) of the rotor (7) is journalled in bearings (10), and has a cooling jacket (21). An oil tank (12) with a pump (11) are provided to feed the oil to the bearings (10). The centrifuge also has a heat exchanger (19) for cooling the oil arranged so as to ensure heat transfer between the oil and cooling agent of the cooling unit (3). The pump (11) is connected through the heat exchanger (19) and cooling jacket (21) to the oil tank (12).
    Type: Grant
    Filed: June 29, 1988
    Date of Patent: July 17, 1990
    Inventors: Boris P. Gorodissky, Jury A. Lotts, Lev N. Veretenov
  • Patent number: 4936821
    Abstract: The liquid being handled is introduced through a centrifugal conduit 1, is separated according to the different density and the two liquid phases exit through conduits 4 and 5. The centrifugal separator comprises disks for sealing (6, 11 and 19) which are fixed respectively to the central part of the rotor 7 to the middle disk 12 and to the upper cover 20 of the apparatus against which the moveable shaped rings (8, 13, 14 and 17) press. The movable rings are subjected to the pressure of the liquid being introduced into the separator as well as the pressure of the two liquid phases being separated by centrifugation due to the difference in specific weight. In this manner, a perfect seal between the different phases is ensured, no biasing means are needed and there is no necessity of particular external cooling.
    Type: Grant
    Filed: July 29, 1988
    Date of Patent: June 26, 1990
    Assignee: Frau S.p.A.
    Inventor: Remo Zuccato
  • Patent number: 4810240
    Abstract: The centrifugal separator is provided with an inlet (1) for the liquid in the center, two exits (4 and 5) for the two phases of different density, rotating seals (13,14,15 and 21) which on contact with rings (10,11,12 and 19) resiliently fixed to the fixed upper part of the separator, guarantee a perfect separation of the liquid and the cooling water under pressure.
    Type: Grant
    Filed: November 3, 1987
    Date of Patent: March 7, 1989
    Assignee: Frau S.p.A.
    Inventor: Remo Zuccato
  • Patent number: 4785637
    Abstract: A thermoelectric cooling design of the type having a nonconducting substrate mounting thermoelectric coolers is improved. Provisions for a flexible can and improved heat dissipation from the thermoelectric coolers are provided. For improved thermal response, the refrigerated vacuum can is provided with thin walls of high purity aluminum with the result that deformation of the wall surface, especially the bottom wall surface can occur both with respect to installation. A plurality of can heat sinks are placed on the walls of the can to form a unitary and locally rigid side wall to the can at the point of attachment. At least one thermoelectric cooler is communicated to the can heat sinks at a first side for receiving heat energy from the can. A second discharge heat sink is communicated to each thermoelectric cooler for dissipating heat energy from both the can and the thermoelectric cooler.
    Type: Grant
    Filed: May 22, 1987
    Date of Patent: November 22, 1988
    Assignee: Beckman Instruments, Inc.
    Inventor: Robert Giebeler
  • Patent number: 4690669
    Abstract: A refrigerated centrifuge in which the bowl is removable from the interior of the casing while leaving the refrigeration coil in place.
    Type: Grant
    Filed: November 27, 1985
    Date of Patent: September 1, 1987
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: John F. Williams, Emery L. Wagner
  • Patent number: 4670003
    Abstract: The invention relates to a method and apparatus for investigating samples of materials subjected to high centrifugal forces, generally in excess of 5.times.10.sup.5 g. The sample is encapsulated in a closed microvessel that serves as a magnetic or magnetizable rotor. The centrifuge provides a rotating magnetic field that drives the microvessel to very high speed, thus subjecting the sample to centrifugation. An optical system coupled with the driving system allows for viewing the sample during rotation.
    Type: Grant
    Filed: October 29, 1985
    Date of Patent: June 2, 1987
    Assignee: Sherwood & Vivin Judson
    Inventor: Pavel E. Moroz
  • Patent number: 4531932
    Abstract: The device comprises a single needle circuit having lines for admitting whole blood drawn from a patient to a continuously rotating rotor, re-introducing red cells and collecting plasma, the lines being respectively connected to the three outlets of a coupling static block rigidly attached to the rotor, two photocell-lightsource assemblies being further provided for automatically cyclically switching over the blood pick up and red cells introduction steps in the device steady state condition of operation.
    Type: Grant
    Filed: November 22, 1982
    Date of Patent: July 30, 1985
    Assignee: Dideco S.p.A.
    Inventors: Libero Luppi, Alessandro Calari
  • Patent number: 4512759
    Abstract: A device for the separation of particles from a stream of gas by centrifugal action, comprising a driven rotatable hollow conically diverging body 1,2 and a feeding apparatus for directing the contaminated gas stream toward the inside wall of said body in the region of its narrowest portion so that the particles will be deposited against said wall and will gradually move toward the widest portion of said conical body; the stream of gas being controlled such that within the body a toroidal eddy forms for the recirculation of the contaminated gas stream.
    Type: Grant
    Filed: February 9, 1983
    Date of Patent: April 23, 1985
    Assignee: Thomassen International B.V.
    Inventors: Aloysius J. W. O. Alink, Berend P. van Marle
  • Patent number: 4498896
    Abstract: A heatable centrifuge is formed of a rotor rotatable about a central axis. The rotor includes a dish shaped portion concentric to the central axis and a jacket portion extending upwardly from the outer peripheral edge of the dish shaped portion and disposed in parallel with the central axis. Preferably, the dish shaped portion is formed of an electrically insulating and heat insulating ceramic material and the jacket portion is formed of a high strength electrically conductive material. Sample containers are symmetrically arranged with the rotor supported with an insert within the jacket portion. Conductive heating members, such as electro-magnets, are arranged about the outer surface of the jacket portion for transmitting heat through the jacket portion to the material being centrifuged.
    Type: Grant
    Filed: October 21, 1975
    Date of Patent: February 12, 1985
    Assignee: Messerschmitt-Bolkow-Blohm
    Inventor: Hans Leis
  • Patent number: 4377253
    Abstract: A coupling assembly for centrifuges is described comprising a rotatable part and a fixed part, a plurality of tubular conduits provided in the fixed part and a corresponding multiplicity of feed and/or discharge passages in the rotatable part, each communicating at one end with one of the tubular conduits and at the other end with the interior of the centrifuging device. The passages are defined in the lateral portion of respective cup-like elements arranged along the axis of the fixed part in fluid-tight connection with each other and with the fixed part.
    Type: Grant
    Filed: January 2, 1981
    Date of Patent: March 22, 1983
    Assignee: Syglo International S.A.
    Inventor: Robert Bruneel