Process Patents (Class 494/37)
  • Publication number: 20110118099
    Abstract: A Microtiter plate centrifuge is disclosed. The centrifuge includes a motor assembly, a rotor assembly attached to the motor assembly via a shaft, the rotor assembly including at least two slots, symmetrically positioned, with respect to the shaft and a channel corresponding to each of said slots. The channels extending from the rotor assembly are suitable for holding Microtiter plates in a vertical position. Also included is a bottom plate engaging a brake pad, which when engaged creates sufficient friction to halt rotation of the rotor assembly.
    Type: Application
    Filed: September 9, 2010
    Publication date: May 19, 2011
    Inventors: Michael D. Rosenblum, H. Gerald Young
  • Publication number: 20110105292
    Abstract: A dual feed centrifuge system for separating solids from fluids in a drilling mud, the centrifuge system including: a bowl; a screw conveyor rotatably mounted within the bowl; a first feed pipe mounted within the screw conveyor for feeding a drilling mud through a first feed port in a wall of the screw conveyor to a first annular space between the bowl and the wall of the screw conveyor; and a second feed pipe mounted within the screw conveyor for feeding a drilling mud through a second feed port in the wall of the screw conveyor to a second annular space between the bowl and the wall of the screw conveyor. The multiple feed ports may allow the centrifuge to operate more efficiently with both weighted and unweighted drilling fluids.
    Type: Application
    Filed: June 5, 2009
    Publication date: May 5, 2011
    Applicant: M-I L.L.C.
    Inventors: Albert Walraven, Bradley N. Jones, Leonardo Renzo Vicentini
  • Patent number: 7935042
    Abstract: A centrifugal separator includes a cylindrical bowl having a conical lower end with an opening through which feed liquid is injected during a feed mode of operation. During the feed mode, solids separate from the feed liquid and accumulate along the inner surface of the bowl as the bowl rotates at high speed. After accumulation of the solids, the rotation of the bowl is stopped and residual liquid is drained by gravity from the bowl. In a solids discharge mode of operation, a piston of a piston assembly is urged downward along a vertical axis in response to fluid such as compressed gas or hydraulic liquid. The downward movement of the piston forces accumulated solids from the bowl via the opening in the conical lower end thereof. The solids pass from the bowl and into a passage leading to an outlet port, where the solids exit the separator.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: May 3, 2011
    Assignee: Wagner Development, Inc.
    Inventor: Robert B. Carr
  • Patent number: 7918350
    Abstract: A separation apparatus and method are employed using a separation channel for rotation about an axis. Such channel includes radially spaced apart inner and outer side wall portions and an end wall portion. An inlet conveys fluid into the channel. A barrier is located in the channel intermediate of the inner and outer side wall portions. A first flow path communicates between upstream and downstream sides of the barrier. A collection region may be located downstream of the barrier for communication with the first flow path. An outer side wall section of the channel may be positioned radially outward of an upstream section thereof. The barrier may join the outer side wall portion along a substantial portion of an axial length of the channel. First and second exit flow paths may allow communication with the channel either upstream or downstream of the barrier or both.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: April 5, 2011
    Assignee: Fenwal, Inc.
    Inventors: Kyungyoon Min, Richard I. Brown, Alp Akonur, Julie Moriarty
  • Publication number: 20110077140
    Abstract: An apparatus for separating a volume of composite liquid into at least a first component and a second component comprising a centrifuge having a rotor with a turntable for supporting a separation bag; a central compartment for containing satellite bags, and fitted with a support member for supporting at least one satellite bag so that a liquid contained in the supported satellite bag drains from the supported satellite bag into the separation bag under centrifugation forces when the rotor is set in rotation.
    Type: Application
    Filed: August 14, 2006
    Publication date: March 31, 2011
    Applicant: GAMBRO BCT, INC.
    Inventors: Brian M. Holmes, Johan-Petter Hagström
  • Patent number: 7914477
    Abstract: The present invention provides an apparatus for separating components of a fluid having an outer housing containing a core and other components wherein three separate fluid pathways are provided to allow continuous separation of biological fluids; this apparatus is particularly useful for the administration of extracorporeal photopheresis in that it enhances the collection of the desired blood components, the return of the treated blood, and the speed with which the therapy is administered.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: March 29, 2011
    Assignee: Therakos, Inc.
    Inventors: Dennis Briggs, Steve Gara, Tom Watters, Mike Hutchinson
  • Patent number: 7909751
    Abstract: A centrifugal separator includes a sample line and a rotating apparatus portion including a rotor that has a rotor chamber. The centrifugal separator centrifugally separates a sample by supplying the sample from the sample line into the rotor and driving to rotate the rotor in the rotor chamber and discharges the centrifugally separated sample from the rotor via the sample line. The centrifugal separator includes a sterilizing apparatus for sterilizing at least a portion with which the sample is brought into contact by making a sterilizing fluid flow through the sample line.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: March 22, 2011
    Assignee: Hitachi Koki Co., Ltd.
    Inventors: Yoshinori Tobita, Masaharu Aizawa, Katsunori Akatsu, Tomohiro Koizumi
  • Publication number: 20110059834
    Abstract: The invention refers to a centrifuge for separating whole blood into its blood components and a method for extracting a highly enriched thrombocyte concentrate out of whole blood. For this purpose, the centrifuge comprises a closed loop and/or open-loop control unit as well as a drive unit coupled to the closed loop and/or open-loop control unit, a rotor (12) having at least two container receptacles (14a, 14b; 16a, 16) for removably holding containers (18, 20, 22, 24) being in fluid communication with each other, at least one sensor arranged between the container receptacles (14a, 14b; 16a, 16b) and coupled with the closed loop and/or open-loop control unit for detecting a separation layer. Herein, a motor/gear unit (30a, 30b, 32a, 32b) coupled to the closed loop and/or open-loop control unit is associated with each of the container receptacles (14a, 14b; 16a, 16b).
    Type: Application
    Filed: September 3, 2010
    Publication date: March 10, 2011
    Applicant: ANDREAS HETTICH GMBH & CO. KG
    Inventor: Klaus-Günter EBERLE
  • Publication number: 20110053752
    Abstract: A centrifugal bowl (105) comprises a base (3) that can rotate about an axis of rotation. A filter sieve in the shape of a perforated peripheral side sieve wall (151) extends from an open end to the base, and a plurality of vanes (155a . . . 155f) is disposed in a predominantly radial direction on the inner surface of the perforated peripheral side sieve wall (151).
    Type: Application
    Filed: December 17, 2008
    Publication date: March 3, 2011
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Michiel Allan Aurelius Schallig, Theodoor Stolk, Martinus Bernardus Stapelbroek, Arif Veendijk, Johannes Rogier de Vrind, Peter Christian Eshuis
  • Patent number: 7897054
    Abstract: A flexible, disposable centrifuge bag for receiving and holding a fluid sample, comprising one or more tubes and upper and lower flexible sheets having doughnut shaped configurations. The upper and lower sheets are superimposed and completely sealed together at their outer perimeters to define an outer perimeter of the centrifuge bag. The inner perimeter of the bag defines a central core. The tubes are sandwiched between the upper and lower sheets and extend from the central core of the centrifuge bag. The upper and lower sheets are sealed together at their inner perimeters such that the tubes are sealed between said upper and lower sheets at the inner perimeter. The bag may be used to harvest platelet rich plasma from whole blood in either a batch method or while simultaneously infusing additional aliquots of whole blood into the bag during centrifugation.
    Type: Grant
    Filed: May 21, 2009
    Date of Patent: March 1, 2011
    Assignee: Arteriocyte Medical Systems, Inc.
    Inventors: Victor D. Dolecek, David Malcolm
  • Publication number: 20110037033
    Abstract: The present teachings provide, in part, methods of separating two-dimensional nanomaterials by atomic layer thickness. In certain embodiments, the present teachings provide methods of generating graphene nanomaterials having a controlled number of atomic layer(s).
    Type: Application
    Filed: August 13, 2010
    Publication date: February 17, 2011
    Inventors: Alexander A. Green, Mark C. Hersam
  • Patent number: 7887862
    Abstract: An apparatus and method for separating joined components, purifying liquid, promoting interaction between two or more components and improving combustion. The apparatus has a housing, a rotor inside of the housing, a plurality of protrusions extending from the rotor, a shaft coupled with the rotor and a prime mover for rotating the shaft. Fluid within the housing cavitates as the rotor rotates and the protrusions move through the fluid. Cavitation causes joined components within the fluid to separate, kills undesirable organisms within the fluid, promotes interaction of components within the fluid and improves combustion of a liquid fuel. The fluid and components may also be subjected to abrasion and centrifugal and impact forces for separating the components, purifying the fluid, promoting interaction of the components and improving combustion.
    Type: Grant
    Filed: October 10, 2007
    Date of Patent: February 15, 2011
    Assignee: Industrias Centli S.A. de C.V.
    Inventors: Fernando Roberto Paz Briz, Fernando Roberto Paz Alcazar
  • Publication number: 20110028297
    Abstract: A centrifugal separator includes a sample line and a rotating apparatus portion including a rotor that has a rotor chamber. The centrifugal separator centrifugally separates a sample by supplying the sample from the sample line into the rotor and driving to rotate the rotor in the rotor chamber and discharges the centrifugally separated sample from the rotor via the sample line. The centrifugal separator includes a sterilizing apparatus for sterilizing at least a portion with which the sample is brought into contact by making a sterilizing fluid flow through the sample line.
    Type: Application
    Filed: October 8, 2010
    Publication date: February 3, 2011
    Applicant: HITACHI KOKI CO., LTD.
    Inventors: Yoshinori Tobita, Masaharu Aizawa, Katsunori Akatsu, Tomohiro Koizumi
  • Publication number: 20110021334
    Abstract: A separator that uses centrifugation to fractionate a suspension such as blood comprises a separation container and a buoy. The buoy is carried in the separation container and has a tuned density that is configured to reach an equilibrium position in a suspension. The guide surface is carried on the buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.
    Type: Application
    Filed: October 4, 2010
    Publication date: January 27, 2011
    Applicants: Biomet Biologics, LLC, Hanuman LLC
    Inventors: Michael D. Leach, Randel Dorian, Jacy C. Hoeppner
  • Publication number: 20110021332
    Abstract: A centrifuge comprises a rotor for holding a sample, a rotation chamber for housing the rotor, a motor for rotating the rotor, an oil diffusion pump for reducing a pressure within the rotation chamber, and a control unit for controlling the heater temperature of the oil diffusion pump for a target set temperature. The control unit changes the target set temperature from a first given temperature to a second given temperature that is lower than the first given temperature after a given period of time elapses since the start of control of the heater temperature.
    Type: Application
    Filed: July 27, 2010
    Publication date: January 27, 2011
    Inventors: Kouichi AKATSU, Masahiro Inaniwa, Hisanobu Ooyama, Shinichi Haruki
  • Publication number: 20110009253
    Abstract: The present invention describes a centrifuge system and method for improving the separation of entrained solids from a solution. The system and method introduces compressed gas to a fluid containing entrained solids to reduce the density and viscosity of the fluid to promote the settling of particles within the solution.
    Type: Application
    Filed: January 30, 2009
    Publication date: January 13, 2011
    Inventor: Daniel Guy Pomerleau
  • Publication number: 20110003677
    Abstract: A centrifuge for separating solid-liquid mixtures including: a rotating bowl having a head wall with at least one drain opening for clarified liquid, said bowl having a rotational axis; a weir plate fixed to the head wall of the bowl and rotating with bowl, wherein the weir plate is aligned with the at least one drain opening; a choke plate coupled to and rotating with the rotating bowl, the choke plate having surface axially aligned with the drain opening or the weir plate, wherein said choke plate is movable axially with respect to the head wall, and a gap having between the drain opening or the weir plate, wherein the gap has a radially inward inlet receiving the clarified liquid from the bowl and a radially outward outlet for discharging the clarified liquid from the bowl.
    Type: Application
    Filed: June 3, 2010
    Publication date: January 6, 2011
    Applicant: ANDRITZ S.A.S.
    Inventors: Gernot Krammer, Laurentiu Pasol, Jean-Marc Huyghe
  • Publication number: 20110003675
    Abstract: A method and apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component and automatically washing at least one component on a centrifuge rotor. The method comprises transferring a wash solution from a wash solution bag on the rotor into a separation bag; mixing the wash solution and a separated blood component; separating and then transferring the sedimented wash solution into a wash solution discard bag on the rotor. The separated blood component may be washed a plurality of times. A disposable set of tube-connected bags comprises a primary bag, initially containing whole blood, connected to at component bags for receiving plasma or platelets and also connected to a wash solution bag and a wash solution discard bag. The disposable set may further comprise a red blood cell collection bag connected through a filter.
    Type: Application
    Filed: June 11, 2010
    Publication date: January 6, 2011
    Applicant: CARIDIANBCT, INC.
    Inventor: Victor D. DOLECEK
  • Publication number: 20110003674
    Abstract: The invention provides a sequential centrifuge for centrifuging discrete samples. Methods of more efficiently centrifuging discrete samples sequentially are also provided. The apparatus and methods for sequentially centrifuging discrete samples provide improved operating efficiencies over conventional batch centrifuges. Such advantages include reducing dwell time, increasing system throughput, reducing sample processing system footprint, and improving precision of the analytical process. The sequential centrifuge further provides the capability of handling critical samples without compromising the operating efficiencies achieved in centrifuging discrete samples in a sequential manner.
    Type: Application
    Filed: December 10, 2008
    Publication date: January 6, 2011
    Inventors: William Alan Fox, Charles L. Carrico
  • Publication number: 20100331162
    Abstract: A fraction collector, sample drier that automatically re-fills sample contains is described. Profiles of RPM and/or back EMF decays as a rotating but unpowered rotor comes to a stop are generated. The profiles may be generated for rotors with full, partially filled and empty sample containers. During a drying operation as the non-volatile samples are collected by evaporating the liquids more sample may be loaded while the rotor is spinning. The operation is to unpower the mechanism and measure the decay profile of PPM and/or EMF over time. A threshold may be set so that the lighter rotor will stop more quickly, and if the threshold is crossed the mechanism will load more sample into the containers.
    Type: Application
    Filed: June 28, 2010
    Publication date: December 30, 2010
    Inventor: Herbert J. Hedberg
  • Publication number: 20100311560
    Abstract: A collection device that captures liquid sample that may spill or leak during the process of loading or unloading liquid sample while a centrifuge rotor is spinning. Such capture prevents the leaked liquid sample from coming into contact with sensitive components inside the centrifuge chamber, thereby protecting the centrifuge from damage.
    Type: Application
    Filed: February 11, 2009
    Publication date: December 9, 2010
    Applicant: BECKMAN COULTER, INC.
    Inventor: Horst G. Krischer
  • Publication number: 20100311559
    Abstract: The invention relates to a centrifuge for separating a sample into at least two components, comprising a chamber for receiving a sample to be centrifuged. According to the invention, the centrifuge further comprises a means for controlling the progress of the sample separation is located at the chamber.
    Type: Application
    Filed: December 8, 2008
    Publication date: December 9, 2010
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschäfer, Martin Biehl, Eiad Kabaha, Jürgen Schulz
  • Patent number: 7837608
    Abstract: A method of preventing blockages of flow paths of a separator, the separator processing a fat-containing product such as milk. The method steps include determining a concentration of the fat content of an outflowing product phase from the separator to detect an imminent clogging, and shifting a separation zone in a separator drum of the separator for a defined minimum time period by changing operating parameters.
    Type: Grant
    Filed: October 30, 2005
    Date of Patent: November 23, 2010
    Assignee: Westfalia Separator AG
    Inventors: Siegfried Klapper, Ludger Bähner
  • Patent number: 7837884
    Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: November 23, 2010
    Assignee: Hanuman, LLC
    Inventors: Randel Dorian, Scott R. King, Richard Wood Storrs
  • Patent number: 7828709
    Abstract: A density centrifuge blood processing system comprising a separation chamber rotating about a central rotation axis, the separation chamber being coupled to an elutriation chamber, a first detector for the separation chamber to detect light from an observation region, a computational apparatus distinguishing at least two regions in the observation region and distinguishing incipient spill over of cellular components out of the elutriation chamber as a function of light intensity received from the at least two regions in the separation chamber, and a controller regulating speed of at least one pump or of the separation chamber in response to signals from the computational apparatus to avoid spill over.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: November 9, 2010
    Assignee: CaridianBCT, Inc.
    Inventor: William Sweat
  • Patent number: 7824502
    Abstract: Tubular labels and contaminants can be removed from containers and/or bottles of plastic material to be recycled, by subjecting the containers and/or bottles to a first weak mechanical washing and slow centrifugating action, followed by a separation step for separating the removed labels and contaminants from the containers. The containers are subsequently subjected to a second strong mechanical washing and fast centrifugating action for the removal from the containers and/or bottles of any residual labels and contaminants.
    Type: Grant
    Filed: September 2, 2008
    Date of Patent: November 2, 2010
    Assignee: Previero N. S.r.l.
    Inventor: Flavio Previero
  • Patent number: 7824559
    Abstract: A PRP separator-concentrator comprising a housing, a separation assembly, and a concentration assembly. The concentration assembly has a concentration sump. An axially concentric rigid stationary outlet tube is secured to the housing and extends through the separation assembly to the sump. The separation assembly is attached to and positioned above the concentration assembly to form a combined separator-concentrator assemblage that is rotatable about the outlet tube. The separation assembly includes a separation chamber lined with a depth filter having pores and passageways that are sized to receive and entrap erythrocytes during centrifuging. The concentration chamber has a floor for supporting desiccated beads and a wall with at least one opening closed with a screen. The concentrator can have a distribution of upright screen supports, the upright screen supports having an inner surface and an outer surface, the cylindrical screen being supported on the outer surface of the upright screen supports.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: November 2, 2010
    Assignees: Hanumann, LLC, Biomet Biologics, LLC
    Inventors: Randel Dorian, Michael D. Leach
  • Publication number: 20100273627
    Abstract: A method for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising centrifuging at least two separation bags containing two discrete volumes of a composite liquid respectively, so as to separate therein the first and second components; transferring at least one fraction of a first separated component from the separation bags into satellite bags connected thereto respectively; detecting a characteristic of a component at determined location in each separation bag; and stopping transferring the at least one fraction of the first component from each separation bag into the first satellite bag connected thereto, upon detection of the characteristic of a component at the determined location.
    Type: Application
    Filed: July 8, 2010
    Publication date: October 28, 2010
    Applicant: CARIDIANBCT, INC.
    Inventors: Darryl HUDOCK, Daniel A. JOSEPH, Victor DOLECEK
  • Publication number: 20100267538
    Abstract: A centrifugal blood processing apparatus comprising a centrifuge rotor, a separation chamber, a tubing set for conducting blood components and fluids and having an inlet line, and an outlet line. Apparatus tests flow conditions using a red light-green light sensor to detect non-recoverable hemolysis during priming by identifying a high R/G ratio, preferably a ratio of greater than or equal to fifty (50), prior to the beginning of the first return of blood components to a donor followed by identifying a R/G ratio at least as great as one and one tenth (1.1) together with a green signal less than a predetermined value, preferably less than or equal to one thousand (1000) reflectance units. If these conditions are detected, an alarm is given and the apheresis procedure is discontinued.
    Type: Application
    Filed: April 15, 2009
    Publication date: October 21, 2010
    Applicant: CARIDIANBCT, INC.
    Inventors: Todd Curtis GREEN, Bruce W. GIBBS
  • Publication number: 20100261596
    Abstract: The presently disclosed subject matter proposes an apparatus (42) and a method for transferring energy and/or a substance from a non-rotating means of an apparatus to a rotating device (43)—or vice versa—through the intermediary of a suitable means (1, 1?).
    Type: Application
    Filed: November 13, 2008
    Publication date: October 14, 2010
    Applicant: MILTENYI BIOTEC GMBH
    Inventors: Winfried Schimmelpfennig, Holger Lantow, Juergen Schulz, Elmar Niklas Neuschaefer
  • Publication number: 20100261595
    Abstract: A gripper unit for handling a vessel for receiving biological material is proposed, inter alia. The vessel has a lid which can assume an open position and a closed position. The gripper unit comprises a gripper for gripping and releasing the vessel, and a lid holder, for holding a lid in a defined position in relation to the vessel. The defined position is an open position of the lid.
    Type: Application
    Filed: September 26, 2006
    Publication date: October 14, 2010
    Inventors: Andreas Schaefer, Thomas Voit, Walter Tschopp, Adrian Geiger, Markus Zbinden, Harald Hibbing, Andreas Karl, Frank Eigemeier, Volker Behrmann, Dietmar Kopp, Andreas Schmiede
  • Patent number: 7811463
    Abstract: A rotatable rotor for separating components contained in a fluid, comprising an annular base having a first annular channel and an annular cover having a second annular channel for holding a flexible doughnut-shaped centrifuge bag therebetween. The cover has one or more radially spaced apart concentric indicator lines for monitoring the separation of the components. When the base and cover are superimposed, the first and second channels define an annular interior chamber having an off-centered figure eight configuration. The base and cover each comprise a grooved column axially centered and extending from the base top surface and the cover bottom surface, respectively. The flexible bag comprises inner and outer tubes extending from the core of the bag and which are seated in the column grooves to ensure that the bag is fixably rotatable with the rotor.
    Type: Grant
    Filed: March 24, 2008
    Date of Patent: October 12, 2010
    Assignee: Arteriocyte Medical Systems, Inc.
    Inventors: Victor D. Dolecek, David Malcolm
  • Publication number: 20100255977
    Abstract: A method and apparatus for separating and concentrating a selected component from a multi-component material. The multi-component material may include a whole sample such as adipose tissue, whole blood, or the like. The apparatus generally includes a moveable piston positioned within a separation container and a withdrawal tube that is operable to interact with a distal end of the collection container past the piston. Material can be withdrawn through the withdrawal tube.
    Type: Application
    Filed: June 17, 2010
    Publication date: October 7, 2010
    Applicant: Biomet Manufacturing Corp.
    Inventors: Michael D. Leach, James M. McKale
  • Patent number: 7803101
    Abstract: A centrifuge includes: a plurality of centrifuge discs each disc having an attachment for attaching a container containing a liquid to be centrifuged; a disc driver positioned to engage and rotate the discs; a disc engager/disengager for individually moving each of said discs into and out of contact with the disc driver; and a controller for controlling which discs are engaged or disengaged from the disc driver and the amount of time each disc is centrifuged. In another embodiment, the centrifuge includes a plurality of disc drivers positioned to engage and rotate the discs, wherein the rotation of discs are controlled by the plurality of disc drivers; and a controller for controlling which discs are rotated by the plurality of disc drivers and the amount of time the discs are centrifuged by individually controlling each disc driver.
    Type: Grant
    Filed: January 30, 2007
    Date of Patent: September 28, 2010
    Assignee: Ortho-Clinical Diagnostics, Inc.
    Inventor: Johannes Porto
  • Publication number: 20100240513
    Abstract: A centrifugal concentrator in which there is a common shaft for the drive motor and concentrator bowl. The cost of bearing assemblies is thereby minimized. The bowl is driven and suspended from above to keep the motor out of the slurry area and maximize the simplicity of the design. A fluidizing fluid is delivered through the common shaft.
    Type: Application
    Filed: October 23, 2007
    Publication date: September 23, 2010
    Inventors: Steven A. McAlister, Mark Henry Vinchoff
  • Patent number: 7789245
    Abstract: A blood separation chamber is provided for separating blood into its constituent parts by rotation about an axis. The chamber has a central hub coinciding with the axis and spaced apart high-G and low-G walls which define therebetween a separation channel. The chamber further includes a plurality of parallel radial walls extending outwardly from the central hub and defining a radial fluid flow passage between each adjacent pair of walls. Each fluid flow passage communicates between the central hub and the separation channel. One of the radial walls includes a radially outer end portion defining a barrier in the separation channel intermediate the low-G and high-G walls and having generally parallel upstream and downstream sides. The separation channel has a recessed portion located radially outward of the high-G wall and extending between the upstream and downstream sides of the barrier.
    Type: Grant
    Filed: August 3, 2009
    Date of Patent: September 7, 2010
    Assignee: Fenwal, Inc.
    Inventors: Tom Westberg, Kelly B Smith, Michel L. F. Joie
  • Publication number: 20100222196
    Abstract: A separation container that can prevent the contamination with unnecessary components is provided. A separation container 1 for separating a separation subject from a sample by causing the separation subject to gather on the bottom thereof by centrifugation includes a container main body 11 and a dividing portion. The container main body 11 is a tubular container elongated in the axial direction with an upper end thereof being open and a lower end thereof being the bottom. The dividing portion has a partition 12 formed along the axial direction of the container main body, and an inner space of the container main body 11 is divided into a sample supply chamber 14 and a separation subject discharge chamber 15 by the partition 12. The sample supply chamber 14 and the separation subject discharge chamber 15 communicate with each other via a through hole 13 formed in a lower portion of the partition 12.
    Type: Application
    Filed: October 23, 2008
    Publication date: September 2, 2010
    Applicant: JMS CO., LTD.
    Inventors: Keiko Ito, Satoshi Hirai, Osamu Okitsu, Yasunori Okamoto
  • Publication number: 20100216215
    Abstract: A method for the simultaneous concentration of multiple toxins from large volumes of water. The method includes the steps of providing a disposable separation centrifuge bowl, the centrifuge bowl including a positively charged material at it's inner core. A large water sample contaminated with toxins from a group consisting of protozoa, bacteria, bacterial spores, and toxins is delivered to the centrifuge bowl. A centrifugal force is applied to the separation bowl. The water sample is concentrated to remove large particles of the toxins in the bowl due to the centrifugal forces. The concentrated water sample is passes through the positively charged inner core to capture any remaining concentrated targets by electrostatic forces and the concentrated targets are eluted.
    Type: Application
    Filed: June 13, 2008
    Publication date: August 26, 2010
    Applicants: TRUSTEES OF TUFTS COLLEGE, HAEMONETICS CORPORATION
    Inventors: Udi Zukerman, Saul Tzipori, Gary Stacey
  • Patent number: 7780861
    Abstract: Contemplated whole blood separators tubes include a curable composition with a density intermediate to the density of serum and the cell-containing fraction. After centrifugation, the curable composition is located between the serum and the cell-containing fraction and preferably irradiated with UV light to initiate a curing reaction in which the curable composition solidifies to a barrier that is immobilized and resistant to breakdown at freezing temperatures and extended storage.
    Type: Grant
    Filed: January 21, 2010
    Date of Patent: August 24, 2010
    Assignee: The Regents of University of California
    Inventor: Jane Emerson
  • Publication number: 20100210441
    Abstract: An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component comprises a centrifuge, which comprising a rotor having a rotation axis, comprising at least one separation cell, for containing a separation bag containing a isolated volume of composite liquid; a satellite cell for containing a satellite bag, and a fluid path between the separation cell and the satellite cell, the path being radially closer to the rotation axis than both the separation cell and the satellite cell and axially above both the separation cell and the satellite cell.
    Type: Application
    Filed: April 28, 2010
    Publication date: August 19, 2010
    Applicant: CARIDIANBCT, INC.
    Inventor: Victor D. DOLECEK
  • Patent number: 7775962
    Abstract: Methods for using a centrifuge are presented. A vessel containing a sample and a separator substance is placed within a centrifuge. Upon sufficient centrifugation, the sample separates into two or more fractions separated by the separator substance. The centrifuge exposes the separator substance to a sufficient energy to polymerize the separator substance to produce a hardened barrier between the fractions.
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: August 17, 2010
    Assignee: The Regents of the University of California
    Inventor: Jane Emerson
  • Patent number: 7775961
    Abstract: Centrifuge samples may be exposed to microwave energy to heat the samples during centrifugation and to promote separation of the different components or constituents of the samples using a centrifuge device configured for generating microwave energy and directing the microwave energy at a sample located in the centrifuge.
    Type: Grant
    Filed: February 6, 2006
    Date of Patent: August 17, 2010
    Assignee: Battelle Energy Alliance, LLC
    Inventor: David H. Meikrantz
  • Patent number: 7758488
    Abstract: A method of operating a separator to disinfect raw milk or whey by operating the separator within a range of an optimal clarifying effect by recirculating a portion of a disinfected milk phase with an entraining liquid.
    Type: Grant
    Filed: May 14, 2005
    Date of Patent: July 20, 2010
    Assignee: West falia Separator AG
    Inventors: Karl-Heinz Zettier, Arnold Uphus, Markus Hüllmann
  • Patent number: 7758816
    Abstract: A cytocentrifuge sample chamber includes a sample receiving well to receive and hold a sample to be centrifuged and a sedimentation chamber adjacent a microscope slide upon which cells and/or other sediment material in the sample is to be deposited. A passage, such as a spillway, connects the sample receiving well and the sedimentation chamber, so that sample flows from the sample well under the influence of centrifugal force as centifugation begins into the sedimentation chamber where the sample is forced by centrifugal force against the microscope slide leaving a vacant space at the inner end of the sedimentation chamber. Sedimentation of the sample takes place against the microscope slide. When centrifugation ends, the liquid components of the sample flow back into the vacant space in the sedimentation chamber and can be removed from the vacant space at the inner end of the sedimentation chamber through a removal chamber.
    Type: Grant
    Filed: March 1, 2007
    Date of Patent: July 20, 2010
    Assignee: Wescor Inc.
    Inventors: Barry O. Stokes, Kevin M. Mullen, Patti A. Nelson, Randal P. Holman
  • Publication number: 20100179043
    Abstract: The present invention relates to a rotor chamber for a centrifuge, in particular an air-cooled laboratory centrifuge, having a chamber wall, comprising an inner side facing toward the chamber interior, the chamber interior being implemented to receive a centrifuge rotor, and an outer side facing away from the chamber interior, and having a sound barrier which is implemented to reduce the sound emitted from the rotor chamber, which comprises a multilayer damping lining. The present invention also relates to a centrifuge having such a rotor chamber, and methods for reducing the sound emanating from the rotor chamber of a centrifuge, in particular an air-cooled laboratory centrifuge.
    Type: Application
    Filed: January 11, 2010
    Publication date: July 15, 2010
    Applicant: THERMO ELECTRON LED GMBH
    Inventor: Hans Janzen
  • Publication number: 20100167899
    Abstract: A hermetically sealed solids discharge centrifugal separator exhibits low-shear filling, acceleration, and separation of feed material. The separator can be particularly useful for separation and recovery of sensitive solids such as chemical or biological substances. The separator accommodates disposable sample contacting elements to eliminate the need for clean-in-place and sterilize-in-place operations. Some embodiments of the separator feature dual solids discharge pistons, which fully optimize recovery of valuable solids.
    Type: Application
    Filed: December 29, 2009
    Publication date: July 1, 2010
    Inventor: Robert B. Carr
  • Publication number: 20100160137
    Abstract: A centrifuge for separating blood and blood components having a blood processing vessel mounted on a rotor of a centrifuge. A sensor in the outflow race of a return peristaltic pump detects air bubbles in the fluid within a return loop. The sensor may be a sonic sensor, a sonic pulse echo sensor, or capacitive plates. A pre-determined minimum bubble size or sizes or a cumulative volume may be selected, and the device operator may be warned only of the existence of bubbles that exceed a certain size or of a cumulative volume of bubbles, or the blood donation procedure may be stopped if a bubble exceeds a certain critical size or if a pre-determined volume of bubbles over a certain period or volume of fluid is exceeded.
    Type: Application
    Filed: December 9, 2009
    Publication date: June 24, 2010
    Applicant: CARIDIANBCT, INC.
    Inventors: Joseph A. SCIBONA, David GIBBONS, John R. LINDNER, William PALSULICH
  • Publication number: 20100160136
    Abstract: Centrifugal separators and related methods and devices are described. More particularly, centrifugal separators comprising a first fluid supply fitting configured to deliver fluid into a longitudinal fluid passage of a rotor shaft and a second fluid supply fitting sized and configured to sealingly couple with the first fluid supply fitting are described. Also, centrifugal separator systems comprising a manifold having a drain fitting and a cleaning fluid supply fitting are described, wherein the manifold is coupled to a movable member of a support assembly. Additionally, methods of cleaning centrifugal separators are described.
    Type: Application
    Filed: December 18, 2008
    Publication date: June 24, 2010
    Applicant: Battelle Energy Alliance, LLC
    Inventors: David H. Meikrantz, Jack D. Law, Troy G. Gam, Lawrence L. Macaluso, Terry A. Todd
  • Publication number: 20100144508
    Abstract: A method for purifying a fluid from contaminating particles in a centrifugal separator by means of a separation aid which is of higher density than the fluid and which binds said particles, the centrifugal separator having a rotor body that rotates about an axis of rotation. The fluid to be purified is led via an inlet into a separation chamber delimited by the rotor body. Separated particles are discharged via a first outlet and clarified fluid cleared is discharged via a second outlet. The fluid being mixed with an amount of separation aid, supplied to the separation chamber. The pollutant particles are bound to the separation aid, which is forced out by the rotation of the rotor body to the periphery thereof. A small flow of separation aid and particles bound thereto are discharged from the separation chamber via the first outlet, and a flow of purified fluid is discharged from the separation chamber via the second outlet.
    Type: Application
    Filed: May 9, 2008
    Publication date: June 10, 2010
    Applicant: ALFA LAVAL CORPORATE AB
    Inventors: Rolf Ridderstrale, Claes Wase
  • Publication number: 20100137120
    Abstract: A spinning force system and methods of operation are provided for measuring a characteristic of a sample. The system includes a detection module having a light source for illuminating the sample and an objective being aligned to the light source to define a light path for producing an image of the sample. A rotor is mechanically coupled to the detection module and configured to rotate the light path for applying a force to the sample. The force may include a centrifugal force and other forms of force (such as a viscous drag force) resulted from the rotation. In some examples, the force is applied in a direction that is not parallel to a surface of the sample.
    Type: Application
    Filed: December 2, 2008
    Publication date: June 3, 2010
    Applicant: President and Fellows of Harvard College
    Inventors: Wesley P. Wong, Kenneth A. Halvorsen