Process Patents (Class 494/37)
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Publication number: 20110118099Abstract: A Microtiter plate centrifuge is disclosed. The centrifuge includes a motor assembly, a rotor assembly attached to the motor assembly via a shaft, the rotor assembly including at least two slots, symmetrically positioned, with respect to the shaft and a channel corresponding to each of said slots. The channels extending from the rotor assembly are suitable for holding Microtiter plates in a vertical position. Also included is a bottom plate engaging a brake pad, which when engaged creates sufficient friction to halt rotation of the rotor assembly.Type: ApplicationFiled: September 9, 2010Publication date: May 19, 2011Inventors: Michael D. Rosenblum, H. Gerald Young
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Publication number: 20110105292Abstract: A dual feed centrifuge system for separating solids from fluids in a drilling mud, the centrifuge system including: a bowl; a screw conveyor rotatably mounted within the bowl; a first feed pipe mounted within the screw conveyor for feeding a drilling mud through a first feed port in a wall of the screw conveyor to a first annular space between the bowl and the wall of the screw conveyor; and a second feed pipe mounted within the screw conveyor for feeding a drilling mud through a second feed port in the wall of the screw conveyor to a second annular space between the bowl and the wall of the screw conveyor. The multiple feed ports may allow the centrifuge to operate more efficiently with both weighted and unweighted drilling fluids.Type: ApplicationFiled: June 5, 2009Publication date: May 5, 2011Applicant: M-I L.L.C.Inventors: Albert Walraven, Bradley N. Jones, Leonardo Renzo Vicentini
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Patent number: 7935042Abstract: A centrifugal separator includes a cylindrical bowl having a conical lower end with an opening through which feed liquid is injected during a feed mode of operation. During the feed mode, solids separate from the feed liquid and accumulate along the inner surface of the bowl as the bowl rotates at high speed. After accumulation of the solids, the rotation of the bowl is stopped and residual liquid is drained by gravity from the bowl. In a solids discharge mode of operation, a piston of a piston assembly is urged downward along a vertical axis in response to fluid such as compressed gas or hydraulic liquid. The downward movement of the piston forces accumulated solids from the bowl via the opening in the conical lower end thereof. The solids pass from the bowl and into a passage leading to an outlet port, where the solids exit the separator.Type: GrantFiled: October 13, 2009Date of Patent: May 3, 2011Assignee: Wagner Development, Inc.Inventor: Robert B. Carr
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Patent number: 7918350Abstract: A separation apparatus and method are employed using a separation channel for rotation about an axis. Such channel includes radially spaced apart inner and outer side wall portions and an end wall portion. An inlet conveys fluid into the channel. A barrier is located in the channel intermediate of the inner and outer side wall portions. A first flow path communicates between upstream and downstream sides of the barrier. A collection region may be located downstream of the barrier for communication with the first flow path. An outer side wall section of the channel may be positioned radially outward of an upstream section thereof. The barrier may join the outer side wall portion along a substantial portion of an axial length of the channel. First and second exit flow paths may allow communication with the channel either upstream or downstream of the barrier or both.Type: GrantFiled: March 6, 2009Date of Patent: April 5, 2011Assignee: Fenwal, Inc.Inventors: Kyungyoon Min, Richard I. Brown, Alp Akonur, Julie Moriarty
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Publication number: 20110077140Abstract: An apparatus for separating a volume of composite liquid into at least a first component and a second component comprising a centrifuge having a rotor with a turntable for supporting a separation bag; a central compartment for containing satellite bags, and fitted with a support member for supporting at least one satellite bag so that a liquid contained in the supported satellite bag drains from the supported satellite bag into the separation bag under centrifugation forces when the rotor is set in rotation.Type: ApplicationFiled: August 14, 2006Publication date: March 31, 2011Applicant: GAMBRO BCT, INC.Inventors: Brian M. Holmes, Johan-Petter Hagström
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Patent number: 7914477Abstract: The present invention provides an apparatus for separating components of a fluid having an outer housing containing a core and other components wherein three separate fluid pathways are provided to allow continuous separation of biological fluids; this apparatus is particularly useful for the administration of extracorporeal photopheresis in that it enhances the collection of the desired blood components, the return of the treated blood, and the speed with which the therapy is administered.Type: GrantFiled: April 19, 2006Date of Patent: March 29, 2011Assignee: Therakos, Inc.Inventors: Dennis Briggs, Steve Gara, Tom Watters, Mike Hutchinson
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Patent number: 7909751Abstract: A centrifugal separator includes a sample line and a rotating apparatus portion including a rotor that has a rotor chamber. The centrifugal separator centrifugally separates a sample by supplying the sample from the sample line into the rotor and driving to rotate the rotor in the rotor chamber and discharges the centrifugally separated sample from the rotor via the sample line. The centrifugal separator includes a sterilizing apparatus for sterilizing at least a portion with which the sample is brought into contact by making a sterilizing fluid flow through the sample line.Type: GrantFiled: October 8, 2010Date of Patent: March 22, 2011Assignee: Hitachi Koki Co., Ltd.Inventors: Yoshinori Tobita, Masaharu Aizawa, Katsunori Akatsu, Tomohiro Koizumi
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Publication number: 20110059834Abstract: The invention refers to a centrifuge for separating whole blood into its blood components and a method for extracting a highly enriched thrombocyte concentrate out of whole blood. For this purpose, the centrifuge comprises a closed loop and/or open-loop control unit as well as a drive unit coupled to the closed loop and/or open-loop control unit, a rotor (12) having at least two container receptacles (14a, 14b; 16a, 16) for removably holding containers (18, 20, 22, 24) being in fluid communication with each other, at least one sensor arranged between the container receptacles (14a, 14b; 16a, 16b) and coupled with the closed loop and/or open-loop control unit for detecting a separation layer. Herein, a motor/gear unit (30a, 30b, 32a, 32b) coupled to the closed loop and/or open-loop control unit is associated with each of the container receptacles (14a, 14b; 16a, 16b).Type: ApplicationFiled: September 3, 2010Publication date: March 10, 2011Applicant: ANDREAS HETTICH GMBH & CO. KGInventor: Klaus-Günter EBERLE
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Publication number: 20110053752Abstract: A centrifugal bowl (105) comprises a base (3) that can rotate about an axis of rotation. A filter sieve in the shape of a perforated peripheral side sieve wall (151) extends from an open end to the base, and a plurality of vanes (155a . . . 155f) is disposed in a predominantly radial direction on the inner surface of the perforated peripheral side sieve wall (151).Type: ApplicationFiled: December 17, 2008Publication date: March 3, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Michiel Allan Aurelius Schallig, Theodoor Stolk, Martinus Bernardus Stapelbroek, Arif Veendijk, Johannes Rogier de Vrind, Peter Christian Eshuis
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Patent number: 7897054Abstract: A flexible, disposable centrifuge bag for receiving and holding a fluid sample, comprising one or more tubes and upper and lower flexible sheets having doughnut shaped configurations. The upper and lower sheets are superimposed and completely sealed together at their outer perimeters to define an outer perimeter of the centrifuge bag. The inner perimeter of the bag defines a central core. The tubes are sandwiched between the upper and lower sheets and extend from the central core of the centrifuge bag. The upper and lower sheets are sealed together at their inner perimeters such that the tubes are sealed between said upper and lower sheets at the inner perimeter. The bag may be used to harvest platelet rich plasma from whole blood in either a batch method or while simultaneously infusing additional aliquots of whole blood into the bag during centrifugation.Type: GrantFiled: May 21, 2009Date of Patent: March 1, 2011Assignee: Arteriocyte Medical Systems, Inc.Inventors: Victor D. Dolecek, David Malcolm
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Publication number: 20110037033Abstract: The present teachings provide, in part, methods of separating two-dimensional nanomaterials by atomic layer thickness. In certain embodiments, the present teachings provide methods of generating graphene nanomaterials having a controlled number of atomic layer(s).Type: ApplicationFiled: August 13, 2010Publication date: February 17, 2011Inventors: Alexander A. Green, Mark C. Hersam
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Patent number: 7887862Abstract: An apparatus and method for separating joined components, purifying liquid, promoting interaction between two or more components and improving combustion. The apparatus has a housing, a rotor inside of the housing, a plurality of protrusions extending from the rotor, a shaft coupled with the rotor and a prime mover for rotating the shaft. Fluid within the housing cavitates as the rotor rotates and the protrusions move through the fluid. Cavitation causes joined components within the fluid to separate, kills undesirable organisms within the fluid, promotes interaction of components within the fluid and improves combustion of a liquid fuel. The fluid and components may also be subjected to abrasion and centrifugal and impact forces for separating the components, purifying the fluid, promoting interaction of the components and improving combustion.Type: GrantFiled: October 10, 2007Date of Patent: February 15, 2011Assignee: Industrias Centli S.A. de C.V.Inventors: Fernando Roberto Paz Briz, Fernando Roberto Paz Alcazar
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Publication number: 20110028297Abstract: A centrifugal separator includes a sample line and a rotating apparatus portion including a rotor that has a rotor chamber. The centrifugal separator centrifugally separates a sample by supplying the sample from the sample line into the rotor and driving to rotate the rotor in the rotor chamber and discharges the centrifugally separated sample from the rotor via the sample line. The centrifugal separator includes a sterilizing apparatus for sterilizing at least a portion with which the sample is brought into contact by making a sterilizing fluid flow through the sample line.Type: ApplicationFiled: October 8, 2010Publication date: February 3, 2011Applicant: HITACHI KOKI CO., LTD.Inventors: Yoshinori Tobita, Masaharu Aizawa, Katsunori Akatsu, Tomohiro Koizumi
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Publication number: 20110021334Abstract: A separator that uses centrifugation to fractionate a suspension such as blood comprises a separation container and a buoy. The buoy is carried in the separation container and has a tuned density that is configured to reach an equilibrium position in a suspension. The guide surface is carried on the buoy upper surface and is inclined to an accumulation position near a buoy perimeter. The buoy suspension fractionation system can be used in a method of isolating a fraction from a suspension, and in a method for re-suspending particulates for withdrawal.Type: ApplicationFiled: October 4, 2010Publication date: January 27, 2011Applicants: Biomet Biologics, LLC, Hanuman LLCInventors: Michael D. Leach, Randel Dorian, Jacy C. Hoeppner
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Publication number: 20110021332Abstract: A centrifuge comprises a rotor for holding a sample, a rotation chamber for housing the rotor, a motor for rotating the rotor, an oil diffusion pump for reducing a pressure within the rotation chamber, and a control unit for controlling the heater temperature of the oil diffusion pump for a target set temperature. The control unit changes the target set temperature from a first given temperature to a second given temperature that is lower than the first given temperature after a given period of time elapses since the start of control of the heater temperature.Type: ApplicationFiled: July 27, 2010Publication date: January 27, 2011Inventors: Kouichi AKATSU, Masahiro Inaniwa, Hisanobu Ooyama, Shinichi Haruki
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Publication number: 20110009253Abstract: The present invention describes a centrifuge system and method for improving the separation of entrained solids from a solution. The system and method introduces compressed gas to a fluid containing entrained solids to reduce the density and viscosity of the fluid to promote the settling of particles within the solution.Type: ApplicationFiled: January 30, 2009Publication date: January 13, 2011Inventor: Daniel Guy Pomerleau
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Publication number: 20110003677Abstract: A centrifuge for separating solid-liquid mixtures including: a rotating bowl having a head wall with at least one drain opening for clarified liquid, said bowl having a rotational axis; a weir plate fixed to the head wall of the bowl and rotating with bowl, wherein the weir plate is aligned with the at least one drain opening; a choke plate coupled to and rotating with the rotating bowl, the choke plate having surface axially aligned with the drain opening or the weir plate, wherein said choke plate is movable axially with respect to the head wall, and a gap having between the drain opening or the weir plate, wherein the gap has a radially inward inlet receiving the clarified liquid from the bowl and a radially outward outlet for discharging the clarified liquid from the bowl.Type: ApplicationFiled: June 3, 2010Publication date: January 6, 2011Applicant: ANDRITZ S.A.S.Inventors: Gernot Krammer, Laurentiu Pasol, Jean-Marc Huyghe
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Publication number: 20110003675Abstract: A method and apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component and automatically washing at least one component on a centrifuge rotor. The method comprises transferring a wash solution from a wash solution bag on the rotor into a separation bag; mixing the wash solution and a separated blood component; separating and then transferring the sedimented wash solution into a wash solution discard bag on the rotor. The separated blood component may be washed a plurality of times. A disposable set of tube-connected bags comprises a primary bag, initially containing whole blood, connected to at component bags for receiving plasma or platelets and also connected to a wash solution bag and a wash solution discard bag. The disposable set may further comprise a red blood cell collection bag connected through a filter.Type: ApplicationFiled: June 11, 2010Publication date: January 6, 2011Applicant: CARIDIANBCT, INC.Inventor: Victor D. DOLECEK
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Publication number: 20110003674Abstract: The invention provides a sequential centrifuge for centrifuging discrete samples. Methods of more efficiently centrifuging discrete samples sequentially are also provided. The apparatus and methods for sequentially centrifuging discrete samples provide improved operating efficiencies over conventional batch centrifuges. Such advantages include reducing dwell time, increasing system throughput, reducing sample processing system footprint, and improving precision of the analytical process. The sequential centrifuge further provides the capability of handling critical samples without compromising the operating efficiencies achieved in centrifuging discrete samples in a sequential manner.Type: ApplicationFiled: December 10, 2008Publication date: January 6, 2011Inventors: William Alan Fox, Charles L. Carrico
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Publication number: 20100331162Abstract: A fraction collector, sample drier that automatically re-fills sample contains is described. Profiles of RPM and/or back EMF decays as a rotating but unpowered rotor comes to a stop are generated. The profiles may be generated for rotors with full, partially filled and empty sample containers. During a drying operation as the non-volatile samples are collected by evaporating the liquids more sample may be loaded while the rotor is spinning. The operation is to unpower the mechanism and measure the decay profile of PPM and/or EMF over time. A threshold may be set so that the lighter rotor will stop more quickly, and if the threshold is crossed the mechanism will load more sample into the containers.Type: ApplicationFiled: June 28, 2010Publication date: December 30, 2010Inventor: Herbert J. Hedberg
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Publication number: 20100311560Abstract: A collection device that captures liquid sample that may spill or leak during the process of loading or unloading liquid sample while a centrifuge rotor is spinning. Such capture prevents the leaked liquid sample from coming into contact with sensitive components inside the centrifuge chamber, thereby protecting the centrifuge from damage.Type: ApplicationFiled: February 11, 2009Publication date: December 9, 2010Applicant: BECKMAN COULTER, INC.Inventor: Horst G. Krischer
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Publication number: 20100311559Abstract: The invention relates to a centrifuge for separating a sample into at least two components, comprising a chamber for receiving a sample to be centrifuged. According to the invention, the centrifuge further comprises a means for controlling the progress of the sample separation is located at the chamber.Type: ApplicationFiled: December 8, 2008Publication date: December 9, 2010Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschäfer, Martin Biehl, Eiad Kabaha, Jürgen Schulz
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Patent number: 7837608Abstract: A method of preventing blockages of flow paths of a separator, the separator processing a fat-containing product such as milk. The method steps include determining a concentration of the fat content of an outflowing product phase from the separator to detect an imminent clogging, and shifting a separation zone in a separator drum of the separator for a defined minimum time period by changing operating parameters.Type: GrantFiled: October 30, 2005Date of Patent: November 23, 2010Assignee: Westfalia Separator AGInventors: Siegfried Klapper, Ludger Bähner
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Patent number: 7837884Abstract: A platelet collection device comprising a centrifugal spin-separator container with a cavity having a longitudinal inner surface. A float in the cavity has a base, a platelet collection surface above the base, an outer surface. The float density is below the density of erythrocytes and above the density of plasma. The platelet collection surface has a position on the float which places it below the level of platelets when the float is suspended in separated blood. During centrifugation, a layer of platelets or buffy coat collects closely adjacent the platelet collection surface. Movement of a float having a density greater than whole blood through the sedimenting erythrocytes releases entrapped platelets, increasing the platelet yield.Type: GrantFiled: December 29, 2008Date of Patent: November 23, 2010Assignee: Hanuman, LLCInventors: Randel Dorian, Scott R. King, Richard Wood Storrs
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Patent number: 7828709Abstract: A density centrifuge blood processing system comprising a separation chamber rotating about a central rotation axis, the separation chamber being coupled to an elutriation chamber, a first detector for the separation chamber to detect light from an observation region, a computational apparatus distinguishing at least two regions in the observation region and distinguishing incipient spill over of cellular components out of the elutriation chamber as a function of light intensity received from the at least two regions in the separation chamber, and a controller regulating speed of at least one pump or of the separation chamber in response to signals from the computational apparatus to avoid spill over.Type: GrantFiled: September 30, 2008Date of Patent: November 9, 2010Assignee: CaridianBCT, Inc.Inventor: William Sweat
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Patent number: 7824502Abstract: Tubular labels and contaminants can be removed from containers and/or bottles of plastic material to be recycled, by subjecting the containers and/or bottles to a first weak mechanical washing and slow centrifugating action, followed by a separation step for separating the removed labels and contaminants from the containers. The containers are subsequently subjected to a second strong mechanical washing and fast centrifugating action for the removal from the containers and/or bottles of any residual labels and contaminants.Type: GrantFiled: September 2, 2008Date of Patent: November 2, 2010Assignee: Previero N. S.r.l.Inventor: Flavio Previero
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Patent number: 7824559Abstract: A PRP separator-concentrator comprising a housing, a separation assembly, and a concentration assembly. The concentration assembly has a concentration sump. An axially concentric rigid stationary outlet tube is secured to the housing and extends through the separation assembly to the sump. The separation assembly is attached to and positioned above the concentration assembly to form a combined separator-concentrator assemblage that is rotatable about the outlet tube. The separation assembly includes a separation chamber lined with a depth filter having pores and passageways that are sized to receive and entrap erythrocytes during centrifuging. The concentration chamber has a floor for supporting desiccated beads and a wall with at least one opening closed with a screen. The concentrator can have a distribution of upright screen supports, the upright screen supports having an inner surface and an outer surface, the cylindrical screen being supported on the outer surface of the upright screen supports.Type: GrantFiled: January 30, 2006Date of Patent: November 2, 2010Assignees: Hanumann, LLC, Biomet Biologics, LLCInventors: Randel Dorian, Michael D. Leach
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Publication number: 20100273627Abstract: A method for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising centrifuging at least two separation bags containing two discrete volumes of a composite liquid respectively, so as to separate therein the first and second components; transferring at least one fraction of a first separated component from the separation bags into satellite bags connected thereto respectively; detecting a characteristic of a component at determined location in each separation bag; and stopping transferring the at least one fraction of the first component from each separation bag into the first satellite bag connected thereto, upon detection of the characteristic of a component at the determined location.Type: ApplicationFiled: July 8, 2010Publication date: October 28, 2010Applicant: CARIDIANBCT, INC.Inventors: Darryl HUDOCK, Daniel A. JOSEPH, Victor DOLECEK
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Publication number: 20100267538Abstract: A centrifugal blood processing apparatus comprising a centrifuge rotor, a separation chamber, a tubing set for conducting blood components and fluids and having an inlet line, and an outlet line. Apparatus tests flow conditions using a red light-green light sensor to detect non-recoverable hemolysis during priming by identifying a high R/G ratio, preferably a ratio of greater than or equal to fifty (50), prior to the beginning of the first return of blood components to a donor followed by identifying a R/G ratio at least as great as one and one tenth (1.1) together with a green signal less than a predetermined value, preferably less than or equal to one thousand (1000) reflectance units. If these conditions are detected, an alarm is given and the apheresis procedure is discontinued.Type: ApplicationFiled: April 15, 2009Publication date: October 21, 2010Applicant: CARIDIANBCT, INC.Inventors: Todd Curtis GREEN, Bruce W. GIBBS
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Publication number: 20100261596Abstract: The presently disclosed subject matter proposes an apparatus (42) and a method for transferring energy and/or a substance from a non-rotating means of an apparatus to a rotating device (43)—or vice versa—through the intermediary of a suitable means (1, 1?).Type: ApplicationFiled: November 13, 2008Publication date: October 14, 2010Applicant: MILTENYI BIOTEC GMBHInventors: Winfried Schimmelpfennig, Holger Lantow, Juergen Schulz, Elmar Niklas Neuschaefer
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Publication number: 20100261595Abstract: A gripper unit for handling a vessel for receiving biological material is proposed, inter alia. The vessel has a lid which can assume an open position and a closed position. The gripper unit comprises a gripper for gripping and releasing the vessel, and a lid holder, for holding a lid in a defined position in relation to the vessel. The defined position is an open position of the lid.Type: ApplicationFiled: September 26, 2006Publication date: October 14, 2010Inventors: Andreas Schaefer, Thomas Voit, Walter Tschopp, Adrian Geiger, Markus Zbinden, Harald Hibbing, Andreas Karl, Frank Eigemeier, Volker Behrmann, Dietmar Kopp, Andreas Schmiede
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Patent number: 7811463Abstract: A rotatable rotor for separating components contained in a fluid, comprising an annular base having a first annular channel and an annular cover having a second annular channel for holding a flexible doughnut-shaped centrifuge bag therebetween. The cover has one or more radially spaced apart concentric indicator lines for monitoring the separation of the components. When the base and cover are superimposed, the first and second channels define an annular interior chamber having an off-centered figure eight configuration. The base and cover each comprise a grooved column axially centered and extending from the base top surface and the cover bottom surface, respectively. The flexible bag comprises inner and outer tubes extending from the core of the bag and which are seated in the column grooves to ensure that the bag is fixably rotatable with the rotor.Type: GrantFiled: March 24, 2008Date of Patent: October 12, 2010Assignee: Arteriocyte Medical Systems, Inc.Inventors: Victor D. Dolecek, David Malcolm
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Publication number: 20100255977Abstract: A method and apparatus for separating and concentrating a selected component from a multi-component material. The multi-component material may include a whole sample such as adipose tissue, whole blood, or the like. The apparatus generally includes a moveable piston positioned within a separation container and a withdrawal tube that is operable to interact with a distal end of the collection container past the piston. Material can be withdrawn through the withdrawal tube.Type: ApplicationFiled: June 17, 2010Publication date: October 7, 2010Applicant: Biomet Manufacturing Corp.Inventors: Michael D. Leach, James M. McKale
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Patent number: 7803101Abstract: A centrifuge includes: a plurality of centrifuge discs each disc having an attachment for attaching a container containing a liquid to be centrifuged; a disc driver positioned to engage and rotate the discs; a disc engager/disengager for individually moving each of said discs into and out of contact with the disc driver; and a controller for controlling which discs are engaged or disengaged from the disc driver and the amount of time each disc is centrifuged. In another embodiment, the centrifuge includes a plurality of disc drivers positioned to engage and rotate the discs, wherein the rotation of discs are controlled by the plurality of disc drivers; and a controller for controlling which discs are rotated by the plurality of disc drivers and the amount of time the discs are centrifuged by individually controlling each disc driver.Type: GrantFiled: January 30, 2007Date of Patent: September 28, 2010Assignee: Ortho-Clinical Diagnostics, Inc.Inventor: Johannes Porto
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Publication number: 20100240513Abstract: A centrifugal concentrator in which there is a common shaft for the drive motor and concentrator bowl. The cost of bearing assemblies is thereby minimized. The bowl is driven and suspended from above to keep the motor out of the slurry area and maximize the simplicity of the design. A fluidizing fluid is delivered through the common shaft.Type: ApplicationFiled: October 23, 2007Publication date: September 23, 2010Inventors: Steven A. McAlister, Mark Henry Vinchoff
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Patent number: 7789245Abstract: A blood separation chamber is provided for separating blood into its constituent parts by rotation about an axis. The chamber has a central hub coinciding with the axis and spaced apart high-G and low-G walls which define therebetween a separation channel. The chamber further includes a plurality of parallel radial walls extending outwardly from the central hub and defining a radial fluid flow passage between each adjacent pair of walls. Each fluid flow passage communicates between the central hub and the separation channel. One of the radial walls includes a radially outer end portion defining a barrier in the separation channel intermediate the low-G and high-G walls and having generally parallel upstream and downstream sides. The separation channel has a recessed portion located radially outward of the high-G wall and extending between the upstream and downstream sides of the barrier.Type: GrantFiled: August 3, 2009Date of Patent: September 7, 2010Assignee: Fenwal, Inc.Inventors: Tom Westberg, Kelly B Smith, Michel L. F. Joie
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Publication number: 20100222196Abstract: A separation container that can prevent the contamination with unnecessary components is provided. A separation container 1 for separating a separation subject from a sample by causing the separation subject to gather on the bottom thereof by centrifugation includes a container main body 11 and a dividing portion. The container main body 11 is a tubular container elongated in the axial direction with an upper end thereof being open and a lower end thereof being the bottom. The dividing portion has a partition 12 formed along the axial direction of the container main body, and an inner space of the container main body 11 is divided into a sample supply chamber 14 and a separation subject discharge chamber 15 by the partition 12. The sample supply chamber 14 and the separation subject discharge chamber 15 communicate with each other via a through hole 13 formed in a lower portion of the partition 12.Type: ApplicationFiled: October 23, 2008Publication date: September 2, 2010Applicant: JMS CO., LTD.Inventors: Keiko Ito, Satoshi Hirai, Osamu Okitsu, Yasunori Okamoto
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Publication number: 20100216215Abstract: A method for the simultaneous concentration of multiple toxins from large volumes of water. The method includes the steps of providing a disposable separation centrifuge bowl, the centrifuge bowl including a positively charged material at it's inner core. A large water sample contaminated with toxins from a group consisting of protozoa, bacteria, bacterial spores, and toxins is delivered to the centrifuge bowl. A centrifugal force is applied to the separation bowl. The water sample is concentrated to remove large particles of the toxins in the bowl due to the centrifugal forces. The concentrated water sample is passes through the positively charged inner core to capture any remaining concentrated targets by electrostatic forces and the concentrated targets are eluted.Type: ApplicationFiled: June 13, 2008Publication date: August 26, 2010Applicants: TRUSTEES OF TUFTS COLLEGE, HAEMONETICS CORPORATIONInventors: Udi Zukerman, Saul Tzipori, Gary Stacey
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Patent number: 7780861Abstract: Contemplated whole blood separators tubes include a curable composition with a density intermediate to the density of serum and the cell-containing fraction. After centrifugation, the curable composition is located between the serum and the cell-containing fraction and preferably irradiated with UV light to initiate a curing reaction in which the curable composition solidifies to a barrier that is immobilized and resistant to breakdown at freezing temperatures and extended storage.Type: GrantFiled: January 21, 2010Date of Patent: August 24, 2010Assignee: The Regents of University of CaliforniaInventor: Jane Emerson
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Publication number: 20100210441Abstract: An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component comprises a centrifuge, which comprising a rotor having a rotation axis, comprising at least one separation cell, for containing a separation bag containing a isolated volume of composite liquid; a satellite cell for containing a satellite bag, and a fluid path between the separation cell and the satellite cell, the path being radially closer to the rotation axis than both the separation cell and the satellite cell and axially above both the separation cell and the satellite cell.Type: ApplicationFiled: April 28, 2010Publication date: August 19, 2010Applicant: CARIDIANBCT, INC.Inventor: Victor D. DOLECEK
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Patent number: 7775962Abstract: Methods for using a centrifuge are presented. A vessel containing a sample and a separator substance is placed within a centrifuge. Upon sufficient centrifugation, the sample separates into two or more fractions separated by the separator substance. The centrifuge exposes the separator substance to a sufficient energy to polymerize the separator substance to produce a hardened barrier between the fractions.Type: GrantFiled: November 1, 2007Date of Patent: August 17, 2010Assignee: The Regents of the University of CaliforniaInventor: Jane Emerson
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Patent number: 7775961Abstract: Centrifuge samples may be exposed to microwave energy to heat the samples during centrifugation and to promote separation of the different components or constituents of the samples using a centrifuge device configured for generating microwave energy and directing the microwave energy at a sample located in the centrifuge.Type: GrantFiled: February 6, 2006Date of Patent: August 17, 2010Assignee: Battelle Energy Alliance, LLCInventor: David H. Meikrantz
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Patent number: 7758488Abstract: A method of operating a separator to disinfect raw milk or whey by operating the separator within a range of an optimal clarifying effect by recirculating a portion of a disinfected milk phase with an entraining liquid.Type: GrantFiled: May 14, 2005Date of Patent: July 20, 2010Assignee: West falia Separator AGInventors: Karl-Heinz Zettier, Arnold Uphus, Markus Hüllmann
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Patent number: 7758816Abstract: A cytocentrifuge sample chamber includes a sample receiving well to receive and hold a sample to be centrifuged and a sedimentation chamber adjacent a microscope slide upon which cells and/or other sediment material in the sample is to be deposited. A passage, such as a spillway, connects the sample receiving well and the sedimentation chamber, so that sample flows from the sample well under the influence of centrifugal force as centifugation begins into the sedimentation chamber where the sample is forced by centrifugal force against the microscope slide leaving a vacant space at the inner end of the sedimentation chamber. Sedimentation of the sample takes place against the microscope slide. When centrifugation ends, the liquid components of the sample flow back into the vacant space in the sedimentation chamber and can be removed from the vacant space at the inner end of the sedimentation chamber through a removal chamber.Type: GrantFiled: March 1, 2007Date of Patent: July 20, 2010Assignee: Wescor Inc.Inventors: Barry O. Stokes, Kevin M. Mullen, Patti A. Nelson, Randal P. Holman
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Publication number: 20100179043Abstract: The present invention relates to a rotor chamber for a centrifuge, in particular an air-cooled laboratory centrifuge, having a chamber wall, comprising an inner side facing toward the chamber interior, the chamber interior being implemented to receive a centrifuge rotor, and an outer side facing away from the chamber interior, and having a sound barrier which is implemented to reduce the sound emitted from the rotor chamber, which comprises a multilayer damping lining. The present invention also relates to a centrifuge having such a rotor chamber, and methods for reducing the sound emanating from the rotor chamber of a centrifuge, in particular an air-cooled laboratory centrifuge.Type: ApplicationFiled: January 11, 2010Publication date: July 15, 2010Applicant: THERMO ELECTRON LED GMBHInventor: Hans Janzen
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Publication number: 20100167899Abstract: A hermetically sealed solids discharge centrifugal separator exhibits low-shear filling, acceleration, and separation of feed material. The separator can be particularly useful for separation and recovery of sensitive solids such as chemical or biological substances. The separator accommodates disposable sample contacting elements to eliminate the need for clean-in-place and sterilize-in-place operations. Some embodiments of the separator feature dual solids discharge pistons, which fully optimize recovery of valuable solids.Type: ApplicationFiled: December 29, 2009Publication date: July 1, 2010Inventor: Robert B. Carr
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Publication number: 20100160137Abstract: A centrifuge for separating blood and blood components having a blood processing vessel mounted on a rotor of a centrifuge. A sensor in the outflow race of a return peristaltic pump detects air bubbles in the fluid within a return loop. The sensor may be a sonic sensor, a sonic pulse echo sensor, or capacitive plates. A pre-determined minimum bubble size or sizes or a cumulative volume may be selected, and the device operator may be warned only of the existence of bubbles that exceed a certain size or of a cumulative volume of bubbles, or the blood donation procedure may be stopped if a bubble exceeds a certain critical size or if a pre-determined volume of bubbles over a certain period or volume of fluid is exceeded.Type: ApplicationFiled: December 9, 2009Publication date: June 24, 2010Applicant: CARIDIANBCT, INC.Inventors: Joseph A. SCIBONA, David GIBBONS, John R. LINDNER, William PALSULICH
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Publication number: 20100160136Abstract: Centrifugal separators and related methods and devices are described. More particularly, centrifugal separators comprising a first fluid supply fitting configured to deliver fluid into a longitudinal fluid passage of a rotor shaft and a second fluid supply fitting sized and configured to sealingly couple with the first fluid supply fitting are described. Also, centrifugal separator systems comprising a manifold having a drain fitting and a cleaning fluid supply fitting are described, wherein the manifold is coupled to a movable member of a support assembly. Additionally, methods of cleaning centrifugal separators are described.Type: ApplicationFiled: December 18, 2008Publication date: June 24, 2010Applicant: Battelle Energy Alliance, LLCInventors: David H. Meikrantz, Jack D. Law, Troy G. Gam, Lawrence L. Macaluso, Terry A. Todd
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Publication number: 20100144508Abstract: A method for purifying a fluid from contaminating particles in a centrifugal separator by means of a separation aid which is of higher density than the fluid and which binds said particles, the centrifugal separator having a rotor body that rotates about an axis of rotation. The fluid to be purified is led via an inlet into a separation chamber delimited by the rotor body. Separated particles are discharged via a first outlet and clarified fluid cleared is discharged via a second outlet. The fluid being mixed with an amount of separation aid, supplied to the separation chamber. The pollutant particles are bound to the separation aid, which is forced out by the rotation of the rotor body to the periphery thereof. A small flow of separation aid and particles bound thereto are discharged from the separation chamber via the first outlet, and a flow of purified fluid is discharged from the separation chamber via the second outlet.Type: ApplicationFiled: May 9, 2008Publication date: June 10, 2010Applicant: ALFA LAVAL CORPORATE ABInventors: Rolf Ridderstrale, Claes Wase
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Publication number: 20100137120Abstract: A spinning force system and methods of operation are provided for measuring a characteristic of a sample. The system includes a detection module having a light source for illuminating the sample and an objective being aligned to the light source to define a light path for producing an image of the sample. A rotor is mechanically coupled to the detection module and configured to rotate the light path for applying a force to the sample. The force may include a centrifugal force and other forms of force (such as a viscous drag force) resulted from the rotation. In some examples, the force is applied in a direction that is not parallel to a surface of the sample.Type: ApplicationFiled: December 2, 2008Publication date: June 3, 2010Applicant: President and Fellows of Harvard CollegeInventors: Wesley P. Wong, Kenneth A. Halvorsen