For Sealing Between Stationary And Moving Elements Patents (Class 494/41)
  • Patent number: 10953409
    Abstract: A centrifugal separator includes a casing which delimits a space which is sealed off from and having an under pressure in relation to the surroundings, by at least one seal. A rotor is arranged for rotation around a rotational axis and forms within itself a separation space. In the separation space, centrifugal separation of at least one higher density component and at least one lower density component from a fluid takes place during operation. At least one inlet extends into the rotor for introducing the fluid to the separation space. At least one first outlet extends from the rotor for discharge of at least one component separated from the fluid during operation. The rotor includes at least one second outlet extending from a portion of the separation space to the space for discharge of at least one higher density component separated from the fluid during operation.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: March 23, 2021
    Assignee: ALFA LAVAL CORPORATE AB
    Inventor: Jouko Pitkämäki
  • Patent number: 10683478
    Abstract: A device for processing a liquid sample containing cells is provided. The device includes a stationary part and a rotatable part. The stationary part includes a cap, a socket connected to the cap, and a tube located within the cap and the socket. The rotatable part includes a centrifugal processing chamber, and a flow guide located within the centrifugal processing chamber. The stationary part and the rotatable part are connected by a plurality of rotary dynamic seals allowing rotation of the rotatable part relative to the stationary part. The cap includes a first port connected to an inlet, and a second port connected to an outlet. The centrifugal processing chamber includes an upper wall, a neck extending from the upper wall, a sidewall and a bottom wall tilting downwardly.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: June 16, 2020
    Inventors: Mo Ma, Bofu Xue
  • Patent number: 10046337
    Abstract: A cleaning in place system for a centrifugal separator and a method of cleaning a centrifugal separator are disclosed. The centrifugal separator includes a rotor having a separation space, a separator inlet and a first separator outlet. The first separator outlet includes an outlet pump configured to provide a flow of fluid from the first separator outlet. The cleaning in place system further includes a container for cleaning fluid, a cleaning fluid pump for providing cleaning fluid from the container to the separator inlet, such as an eductor. The cleaning in place system is configured to receive a flow of fluid from the first separator outlet and that the cleaning fluid pump is configured to pump cleaning fluid from the container to the separator inlet by means of the received flow of fluid.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: August 14, 2018
    Assignee: ALFA LAVAL CORPORATE AB
    Inventor: Neil Whitehead
  • Patent number: 9308314
    Abstract: A continuous centrifugal blood separation device has a simple and reliable structure. The continuous blood centrifugal device includes an RBC (red blood cell) collector that is coaxial with a supernatant collector. The continuous blood centrifugal device includes an axial symmetric barrier disposed between the RBC collector and the supernatant collector in order to avoid turbulence that can otherwise be caused by the supernatant collector.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: April 12, 2016
    Assignee: Sorin Group Italia S.r.l.
    Inventors: Andrea Galavotti, Elisa Maculan, Gianpaolo Simonini
  • Publication number: 20140235422
    Abstract: A centrifugal separator includes a frame and a rotating part including a spindle and a centrifuge rotor enclosing a separation space. An inlet channel provides fluid communication into the separation space and includes a rotary channel part, a frame channel part, and a first seal at the interface between the rotary and frame channel parts. An outlet channel provides fluid communication out from the separation space and includes a rotary channel part, a frame channel part, and a second seal at the interface between the rotary and frame channel parts. The inlet and outlet channels are arranged concentrically with each other. A forcing device is provided to generate a leak flow through one of the first and second seals in a first direction from the outlet channel to the inlet channel and to counteract leakage in the opposite direction.
    Type: Application
    Filed: August 31, 2012
    Publication date: August 21, 2014
    Applicant: ALFA LAVAL CORPORATE AB
    Inventors: Roland Isaksson, Peter Thorwid
  • Patent number: 8758210
    Abstract: An apparatus for performing a centrifugal field-flow fractionation is disclosed. In an embodiment of the invention, radial rotary shaft seals are used for sealing the rotating parts of the shaft for carrying out the centrifugal field-flow fractionation and the stationary parts. Furthermore, a separate line is introduced for reducing the pressure differential across these seals. In such way, the driving force driving sample fluid across the seals is reduced, thereby reducing leakage.
    Type: Grant
    Filed: May 21, 2012
    Date of Patent: June 24, 2014
    Assignee: Postnova Analytics GmbH
    Inventor: Roland Welz
  • Patent number: 8652021
    Abstract: A decanter-type centrifugal separator equipped with a continuous lubricant supply device capable of preventing leakage of lubricating oil along supply pathways, and supplying and discharging lubricating oil. The continuous lubricant supply device has a lubricating oil supply channel formed inside a bowl hub, an annular introduction channel that introduces lubricating oil into the lubricating oil supply channel, a lubricating oil infusion channel formed inside a holder, and an oil collector installed on an outer surface of an outer shaft. The annular introduction channel has a first annular groove formed inside the holder such that the groove is occluded on the inside by the outer surface of the outer shaft. The oil collector can orbitally revolve in a predetermined direction inside the annular introduction channel, thereby moving lubricating oil radially inward in the annular introduction channel so as to flow into the lubricating oil supply channel.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: February 18, 2014
    Assignee: Tomoe Engineering Co., Ltd.
    Inventors: Takeo Yumoto, Toshio Tagami
  • Publication number: 20130345039
    Abstract: Described herein is a centrifuge separator for separating a mixture of an immiscible solid and liquid, particularly where the solid has a lower specific gravity (i.e. is lighter) than the liquid. Methods of use and a rotary seal are also described herein.
    Type: Application
    Filed: January 27, 2012
    Publication date: December 26, 2013
    Applicant: SCOTT SEPARATION TECHNOLOGY LIMITED
    Inventor: Ross Allan Ward
  • Patent number: 8574143
    Abstract: A horizontal solid-bowl centrifuge with cleaning-in-place jet nozzles for cleaning the bowl in a manner complying with good manufacturing procedure is provided. The bowl is cleaned by a defined arrangement of the cleaning jet nozzles, as the bowl rotates at a speed insufficient to produce a centrifugal force equal to gravitational acceleration, where gravitational acceleration is equal to 1.0 g. The cleaning liquids are then removed after the bowl stops rotating at the lowest point of the bowl.
    Type: Grant
    Filed: September 19, 2007
    Date of Patent: November 5, 2013
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Achim Astheimer, Peter Kraemer, Wolfgang Sittig, Bernhard Unger, Frank Zwilling
  • Patent number: 8540613
    Abstract: To enable centrifugal filtration of fluids which contain abrasive contaminant particles the rotor bearings (3) must be isolated from the fluid which passes into and through the rotor chamber (21). This is achieved by a design in which the spindle (4) is connected to the rotor so as to rotate in unison with the rotor (5, 6, 7) relative to the base (1). The bearings (3) for the spindle (4) are provided in a bearing housing (2) which is fixedly mounted to the base (1) and a sealing arrangement, preferably a spring-loaded axial seal (14, 15), is provided between the spindle (4) and the base (1) at a location below the bearings (3) in the bearing housing (2).
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: September 24, 2013
    Assignee: Mann +Hummel GmbH
    Inventors: Nigel Burford, Anthony W. Fell, Klemens Dworatzek, Nicholas Foulkes, John Lawrence Mills
  • Patent number: 8475351
    Abstract: The present invention provides a zonal centrifuge which has superior workability and functionality when a sample is filled and extracted. An oil bearing fitted to an outer circumference of a lower tube of a rotor is arranged on an internal face of a bearing housing fixed over a door adapter of the centrifuge. As the oil bearing and the lower tube are lubricated, a vacuum environment in a rotor rotating chamber is maintained. A rotating seal located at an upper leading end of the lower tube of the rotor and a fixing seal facing the rotating seal are arranged and provided in a sealed space formed by a mechanical seal member and the bearing housing, and the fixing seal is so manipulated as to be able to freely join and separate from the rotating seal.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: July 2, 2013
    Assignee: Hitachi Koki Co., Ltd.
    Inventor: Masaharu Aizawa
  • Patent number: 8348823
    Abstract: A disposable device for the continuous centrifugal separation of a physiological fluid includes: a fixed axial element; a centrifugation chamber that can rotate around the axis of the element; an inlet channel for the blood to be centrifuged, whose dispensing port is close to the base of the chamber; and an outlet passage for a separated constituent, whose inlet port is close to the other end of the chamber in a concentrated area of one of the separated constituents having the lowest mass density in order to remove it continuously. The chamber takes the form of a long tube. The fixed axial element includes a second outlet passage for a second separated constituent, whose inlet port is close to the end of the chamber opposite the base in a concentrated area of the second separated constituent having the highest mass density in order to remove it continuously.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: January 8, 2013
    Inventor: Jean-Denis Rochat
  • Publication number: 20130005559
    Abstract: To enable centrifugal filtration of fluids which contain abrasive contaminant particles the rotor bearings (3) must be isolated from the fluid which passes into and through the rotor chamber (21). This is achieved by a design in which the spindle (4) is connected to the rotor so as to rotate in unison with the rotor (5, 6, 7) relative to the base (1). The bearings (3) for the spindle (4) are provided in a bearing housing (2) which is fixedly mounted to the base (1) and a sealing arrangement, preferably a spring-loaded axial seal (14, 15), is provided between the spindle (4) and the base (1) at a location below the bearings (3) in the bearing housing (2).
    Type: Application
    Filed: September 11, 2012
    Publication date: January 3, 2013
    Applicant: MANN+HUMMEL GMBH
    Inventors: Nigel Burford, Anthony W. Fell, Klemens Dworatzek, Nicholas Foulkes, John Lawrence Mills
  • Publication number: 20120295782
    Abstract: A hermetic centrifugal separator for centrifuging components, contained in a liquid mixture and having different density, comprises a rotating centrifuge rotor, which is arranged to rotate around a centre axis and comprises a casing which defines an inner separation space, a set of separation discs which are provided in the inner separation space of the centrifuge rotor, at least two channels, which connect to the separation space and comprise at least one inlet channel for supply of the liquid mixture of components to be separated to the separation space and at least one outlet channel for discharge of a component separated during operation from the separation space, a torque transmitting part around the centre axis and fixedly connected to the centrifuge rotor adapted to be driven in such a way that the centrifuge rotor is brought to rotate, outlet sealing means arranged to seal between the outlet channel and the rotating centrifuge rotor preventing entrainment of unwanted substances.
    Type: Application
    Filed: November 3, 2010
    Publication date: November 22, 2012
    Applicant: ALFA LAVAL CORPORATE AB
    Inventors: Jouko Pitkämäki, Robert Sandblom
  • Publication number: 20120245013
    Abstract: The spinning disc centrifuge rotor includes a sample holder formed from a cylindrical disc body and a cover plate that are made from a transparent material, such as polycarbonate, preferably Lexan® (Lexan is a registered trademark of General Electric Company of Schenectady, N.Y.). The disc-shaped body has two concentric or coaxial recesses defined therein. The first recess forms a cylindrical well or sample chamber for receiving a generally cylindrical rock sample. The second recess has a larger diameter than the first recess, and is shallower, forming a fluid collection area above the sample well, the second recess forming an annular ring extending around the top edge or rim of the sample well. An O-ring snugly within the outer wall of the second recess and forms a seal between the cover plate and the floor of the second recess, preventing fluid leakage. A rotor shaft extends from the bottom face of the cylindrical disc.
    Type: Application
    Filed: March 21, 2011
    Publication date: September 27, 2012
    Applicant: KUWAIT UNIVERSITY
    Inventor: OSAMAH ALI ALOMAIR
  • Publication number: 20120220441
    Abstract: A continuous flow centrifuge system is provided. The system includes a rotor, a stator, a stator housing, upper and lower bearing plates, upper and lower bearings, first and second snap rings, and lip seal. The upper bearing rotatably secures a shaft of the rotor in the upper bearing plate. The first snap ring secures the upper bearing to the rotor shaft. The lip seal is over the upper bearing and forms a rotatable seal with the upper bearing plate. The second snap ring secures the lip seal to an inner diameter of the upper bearing plate. The upper and lower bearing plates are secured to the stator housing so that the rotor is operatively aligned with the stator.
    Type: Application
    Filed: May 3, 2012
    Publication date: August 30, 2012
    Applicant: ALFA WASSERMANN, INC.
    Inventors: Kurt Spiegel, Sorin Weissman, Bill Lepse, Blaine J. Marsh
  • Publication number: 20120100980
    Abstract: A centrifuge opening tool has a frame that securely holds a centrifuge drum therein. An upright tube is mounted to the frame and a brake band is rotatably secured to the upright tube. When the brake band is tightened, the centrifuge drum is securely held in place. A ring gear is secured to a lock ring. The lock ring is part of the centrifuge drum and is removable to allow access to the interior therein. A drive gear meshes with the ring gear and increases the mechanical advantage allowing a user to apply the force needed to open the lock ring even when it has been extremely compressed. A spanner wrench is placed on a drive shaft that is connected to the drive gear. Engagement pins are used to mechanically couple the gear ring and lock ring together.
    Type: Application
    Filed: October 21, 2011
    Publication date: April 26, 2012
    Inventor: Thomas Lahmann
  • Publication number: 20120040816
    Abstract: The invention relates to a centrifugal separator comprising a casing which delimits and seals off a space in which a rotor is arranged. The rotor forms a separation space which is sealed or isolated from the space, and in which separation space centrifugal separation of a higher density and a lower density component from a fluid takes place. An inlet extends into the rotor for introducing fluid to the separation space, and a first outlet extends from the rotor for discharge of a component separated from the fluid. The space is connected to a pump device which is arranged to remove gas, thereby maintaining negative pressure in said space. The rotor comprises at least one second outlet extending from the separation space to the space for discharge of at least one higher density component separated from the fluid. The invention also relates to a method in such a centrifugal separator.
    Type: Application
    Filed: March 5, 2010
    Publication date: February 16, 2012
    Applicant: ALFA LAVAL CORPORATE AB
    Inventors: Peter Thorwid, Roland Isaksson, Peter Hagqvist, Carl Häggmark, Lars Hillström
  • Patent number: 8096933
    Abstract: A centrifuge with an electric motor (46), composed of a centrifuge outer frame (47), a heavy liquid collecting tank (18), a lower hollow shaft (22), centrifugal units, an upper hollow shaft (38), and a light liquid collecting tank (41). The heavy liquid collecting tank, the lower hollow shaft, the upper hollow shaft, and the light liquid collecting tank are all fixed to the centrifuge outer frame, the centrifugal units are fixed between the upper hollow shaft and the lower hollow shaft, the motor is connected to the upper hollow shaft and drives the upper hollow shaft to rotate, the upper hollow shaft is fixed to two or more centrifugal units connected in series and drives the centrifugal units to rotate, a hollow portion of the upper hollow shaft communicates with the light liquid collecting tank, centrifugal units are fixed to the lower hollow shaft and drive the lower hollow shaft to rotate, the heavy liquid collecting tank is a casing formed between the centrifuge outer frame and the centrifugal units.
    Type: Grant
    Filed: October 20, 2006
    Date of Patent: January 17, 2012
    Inventor: Shujiang Song
  • Patent number: 8070664
    Abstract: The invention relates to disposable device for the continuous centrifugal separation of a physiological fluid. The inventive device comprises: a fixed axial element; a centrifugation chamber which is mounted such that it can rotate around the axis of said element; an inlet channel for the blood to be centrifuged, the dispensing port of which is located close to the base of the chamber; and an outlet passage for a separated constituent, the inlet port of which is located close to the other end of the chamber in a concentrated area of one of the separated constituents having the lowest mass density in order for same to be removed continuously. The above-mentioned chamber takes the form of a long tube.
    Type: Grant
    Filed: January 23, 2006
    Date of Patent: December 6, 2011
    Inventor: Jean-Denis Rochat
  • Patent number: 8070667
    Abstract: The invention relates to a centrifugation enclosure (1) made of rigid plastic that comprises a member (1b) adapted to engage with the driving organ of a centrifugation machine (M) and a communication member (5) between the enclosure (1) and the outside, made of rigid plastic and comprising un first duct (5a) extending therethrough for supplying said enclosure (1) as well as two ducts (5b, 5c) extending therethrough for discharging the separated components. A holder (3) made of rigid plastic and having a network of channels (4a, 4b, 4c) formed therein connects the ducts (5a, 5b, 5c), respectively, to supply (P1) and reception (P2, P3) tanks, with side sealing members (6) of said channel network (4a, 4b, 4c). The ends of the ducts (5a, 5b, 5c) are adjacent to the respective ends of the channels (4a, 4b, 4c), and the ends of the ducts (5a, 5b, 5c) have surfaces mating with the end surfaces of the respective channels (4a, 4b, 4c), said mating surfaces being connected to one another.
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: December 6, 2011
    Inventor: Jean-Denis Rochat
  • Patent number: 8070666
    Abstract: A disposable device for centrifugation of blood is used for separating or also washing constituents of the blood includes a centrifugation chamber with a revolving shaft and an opening through which the shaft passes, a rotational guide, a rotational driver, and at least one static member for admission/evacuation engaged in the centrifugation chamber. This member includes at least one channel for intake of the blood and at least one outlet channel for one of its constituents, and at least one admission channel for a pressurized gaseous fluid which opens out inside the centrifugation chamber. A gap is formed in the opening between the centrifugation chamber and the static member and allows the gaseous fluid to escape from the centrifugation chamber.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: December 6, 2011
    Inventor: Jean-Denis Rochat
  • Publication number: 20110287920
    Abstract: A vertical separator has a bowl which is supported for rotation about a vertical axis and from beneath, providing an unobstructed inlet to the bowl. Conveyor fighting, located concentrically for independent co-rotation within the bowl, directs solids to the bottom of the bowl while the liquids flow along an annular clearance along the bowl wall to an upper end of the bowl. A feedstream, such as drilling mud shaker solids, which may otherwise require augers or the like to feed the feedstream through a conventional horizontal centrifuge, can be received at the inlet by gravity feed and residual liquids stripped therefrom.
    Type: Application
    Filed: May 19, 2011
    Publication date: November 24, 2011
    Applicant: KAYDEN INDUSTRIES INC.
    Inventors: Russ FISHER, Darcy SMITH
  • Patent number: 8038592
    Abstract: A centrifuge includes a rotor, a rotation shaft which has a through-hole communicated with an interior of the rotor, a face seal which slidingly contacts an end of the rotation shaft and has a path communicated with the through-hole of the rotation shaft, a wall member which accommodates the face seal, a sample transfer unit which transfers a sample through the rotor, and a coolant circulation unit which circulates a coolant to the wall member. The sample transfer unit transfers the sample by pressure so that a pressure of the sample flowing through a portion where the rotation shaft and the face seal slidingly contact with each other is higher than a pressure of the coolant flowing through the wall member.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: October 18, 2011
    Assignee: Hitachi Koki Co., Ltd.
    Inventors: Hiroatsu Toi, Eiichi Fukuhara
  • Publication number: 20110224062
    Abstract: The invention relates to a method and a device for separating blood using a centrifuge in order to obtain different blood fractions. The aim of the invention is to eliminate the risk of contamination during the supply of blood and the removal of blood fractions. To achieve this, the separation container is filled with blood via a feed connection that can be aseptically connected to the container, the relevant blood fraction is removed from the separation container via a removal connection that can be aseptically connected to the container and both the feed device and the removal device form a respective closed system during the sterile connection to the separation container. The separation container (4) has at least one feed connection (5, 6) that can be aseptically connected to the container and at least one removal connection (7) that can be aseptically connected to the container, to which hermetically sealed feed and removal devices (8, 9, 10) can be aseptically attached in a sterile manner.
    Type: Application
    Filed: September 13, 2009
    Publication date: September 15, 2011
    Inventor: Walter Pobitschka
  • Patent number: 7998051
    Abstract: In a centrifugal separator comprising a first and second separator part having a centrifuge rotor and rotates during operation relative to the first separator part. A space connecting the first and second separator parts houses a rotating liquid body during operation. A mechanical sealing device is provided at the space and includes a first sealing element on the first separator part having a first contact surface, and a second sealing element on the second separator part having a second contact surface. The liquid body on the first sealing element or the second sealing element and displaces the same axially so that the first and second contact surfaces are pressed against each other. A pre-tensioning element exerts force on the sealing element which acts to displace the first contact away from the second contact surfaces so that a gap is formed, forming a throttling.
    Type: Grant
    Filed: June 12, 2007
    Date of Patent: August 16, 2011
    Assignee: Alfa Laval Corporate AB
    Inventor: Kjell Klintenstedt
  • Patent number: 7998052
    Abstract: A rotor having variable volumes adapted for collecting and centrifuging biological fluids including an impermeable flexible body having a cylindrical shape with stretchable vertical walls and semi pliant base and a rigid circular member seamlessly joined to the top of the flexible body.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: August 16, 2011
    Inventor: Jacques Chammas
  • Publication number: 20110183830
    Abstract: A centrifuge for separating solids from a liquid including a centrifuge rotor with a rotor shaft, partially formed as a hollow shaft, and a centrifuging drum, being rotatable with the rotor shaft, wherein the liquid to be separated can be supplied via the cavity of the hollow shaft. To ease emptying of the drum, the centrifuging drum includes a drum lower part and a drum upper part, which bears loosely against the drum lower part. The upper part is guided in an axially movable manner on the shaft and is movable by means of a disengagement mechanism parallel to the rotor axis into an open position in which, for self-emptying of the interior space, the drum parts are spaced apart from one another while they still rotate with the rotor shaft.
    Type: Application
    Filed: August 17, 2009
    Publication date: July 28, 2011
    Applicant: BOLL & KIRCH FILTERBAU GMBH
    Inventors: Carsten Tietze, Gerd Stahl
  • Publication number: 20100081553
    Abstract: The present invention provides a zonal centrifuge which has superior workability and functionality when a sample is filled and extracted. An oil bearing fitted to an outer circumference of a lower tube of a rotor is arranged on an internal face of a bearing housing fixed over a door adapter of the centrifuge. As the oil bearing and the lower tube are lubricated, a vacuum environment in a rotor rotating chamber is maintained. A rotating seal located at an upper leading end of the lower tube of the rotor and a fixing seal facing the rotating seal are arranged and provided in a sealed space formed by a mechanical seal member and the bearing housing, and the fixing seal is so manipulated as to be able to freely join and separate from the rotating seal.
    Type: Application
    Filed: September 21, 2009
    Publication date: April 1, 2010
    Inventor: Masaharu AIZAWA
  • Publication number: 20100048373
    Abstract: The invention relates to a centrifugation enclosure (1) made of rigid plastic that comprises a member (1b) adapted to engage with the driving organ of a centrifugation machine (M) and a communication member (5) between the enclosure (1) and the outside, made of rigid plastic and comprising an first duct (5a) extending therethrough for supplying said enclosure (1) as well as two ducts (5b, 5c) extending therethrough for discharging the separated components. A holder (3) made of rigid plastic and having a network of channels (4a, 4b, 4c) formed therein connects the ducts (5a, 5b, 5c), respectively, to supply (P1) and reception (P2, P3) tanks, with side sealing members (6) of said channel network (4a, 4b, 4c). The ends of the ducts (5a, 5b, 5c) are adjacent to the respective ends of the channels (4a, 4b, 4c), and the ends of the ducts (5a, 5b, 5c) have surfaces mating with the end surfaces of the respective channels (4a, 4b, 4c), said mating surfaces being connected to one another.
    Type: Application
    Filed: October 4, 2007
    Publication date: February 25, 2010
    Inventor: Jean-Denis Rochat
  • Publication number: 20090280974
    Abstract: In a centrifugal separator comprising a first and second separator part having a centrifuge rotor and rotates during operation relative to the first separator part. A space connecting the first and second separator parts houses a rotating liquid body during operation. A mechanical sealing device is provided at the space and includes a first sealing element on the first separator part having a first contact surface, and a second sealing element on the second separator part having a second contact surface. The liquid body on the first sealing element or the second sealing element and displaces the same axially so that the first and second contact surfaces are pressed against each other. A pre-tensioning element exerts force on the sealing element which acts to displace the first contact away from the second contact surfaces so that a gap is formed, forming a throttling.
    Type: Application
    Filed: June 12, 2007
    Publication date: November 12, 2009
    Applicant: ALFA LAVAL CORPORATE AB
    Inventor: Kjell Klintentedt
  • Patent number: 7503889
    Abstract: The present invention provides an apparatus for separating components of a fluid having an outer housing containing a core wherein three separate fluid pathways are provided to allow continuous separation of biological fluids.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: March 17, 2009
    Inventors: Dennis Briggs, Steve Gara, Tom Watters, Mike Hutchinson
  • Patent number: 7452322
    Abstract: A rotor for collecting and centrifuging biological fluids in a range of volumes. The rotor includes an elastic impermeable diaphragm which defines at least a portion of a variable-volume processing chamber, where the fluid is centrifuged. The rotor includes a rigid mounting member, to which the diaphragm is mounted and which is held and spun by a chuck. Preferably, this rigid mounting member includes a boundary wall which together with the elastic diaphragm defines the chamber. The boundary wall may be a substantially imperforate circular wall which extends to the periphery of the processing chamber but defining one opening, preferably near the axis of rotation, permitting a conduit or conduits to pass therethrough so as to be in fluid communication with the processing chamber. The rotor may include a separate structure for controlling the flow of liquid out of the chamber into the conduit.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: November 18, 2008
    Assignee: Haemonetics Corporation
    Inventors: Thomas D. Headley, Edward T. Powers
  • Publication number: 20080128367
    Abstract: The inventive method for centrifugal separation of a determined volume of physiological liquid, in particular blood, at initial process step, consists in forming a flow of said liquid whose thickness is close to the size of largest particles (L3) contained therein at a volume ratio of <1%, in decelerating said liquid flow in order to increase the thickness thereof and to transfer said largest particles (L3) to the surface of the liquid phase (L1) which is nearest to a centrifugation axis and whose density is the greatest, in arranging, outside of said surface, a dead volume whose capacity is substantially equal to the volume of said largest particles (L3) and in removing a phase (L2) whose density is the lowest.
    Type: Application
    Filed: February 1, 2006
    Publication date: June 5, 2008
    Inventor: Jean-Denis Rochat
  • Patent number: 7331919
    Abstract: A centrifugal drum for a separator having a vertical axis of rotation, including a drum bottom part and a drum cover fastened to the drum bottom part by a locking ring. Also included is a centering ring arranged between the drum bottom part and the drum cover such that while the centering ring is being pretensioned, it sealingly and centeringly braces the drum bottom part and the drum cover relative to one another.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: February 19, 2008
    Assignee: Westfalia Separator AG
    Inventor: Willi Niemerg
  • Patent number: 7074173
    Abstract: A centrifuge including a centrifugal drum that includes a centrifugal chamber and a centrifugal chamber bottom part displaceable relative to the centrifugal drum. Also included is a piston slide axially displaceably arranged to be in and/or on the centrifugal drum. At least one seal is arranged in a surrounding groove on an outer circumference of the centrifugal drum bottom part and further arranged between the piston slide and the outer circumference of the centrifugal chamber bottom part to seal off a gap between the piston slide and the centrifugal chamber bottom part. The groove is configured to be constructed at least in sections and axially open toward the centrifugal chamber.
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: July 11, 2006
    Assignee: Westfalia Separator AG
    Inventors: Werner Kohlstette, Willi Niemerg, Thomas Kleimann
  • Patent number: 7060018
    Abstract: A centrifuge apparatus for processing blood comprising a bottom spring-loaded support plate; a top support plate; an axial inlet/outlet for blood to be processed and processed components of the blood, the axial inlet/outlet being attached to the top support plate by a rotating seal assembly; a variable volume separation chamber mounted between the bottom support plate and the top support plate, the variable volume separation chamber being fluidly connected to the axial inlet/outlet; a pump fluidly connected to the axial inlet/outlet; and a rotary drive unit attached to the bottom support plate. The top support plate is fixed vertically and the bottom spring-loaded support plate is mounted on springs that maintain pressure on the variable volume separation chamber and allow the bottom support plate to move vertically.
    Type: Grant
    Filed: September 11, 2003
    Date of Patent: June 13, 2006
    Assignee: COBE Cardiovascular, Inc.
    Inventors: David W. Skinkle, Stephen W. Berch
  • Patent number: 6986733
    Abstract: A solid bowl helical conveyor centrifuge. The centrifuge includes a rotating drum, having a centrifuge space with a screw that can also rotate. An inlet tube for supplying a material for centrifugation into the centrifuge space, and at least one liquid discharge and at least one solids discharge, wherein the liquid discharge and/or the solid discharge is/are designed as at least one or more openings in a rotating part of the solid bowl helical conveyor centrifuge, in particular through openings in the drum wall. At least one of the openings is covered by a housing which encloses the drum of the solid bowl helical conveyor centrifuge in only some sections, between the at least one housing and the drum and/or other rotating elements of the solid bowl helical conveyor centrifuge (drum heads, hubs) at least one or more gaskets are provided.
    Type: Grant
    Filed: April 1, 2004
    Date of Patent: January 17, 2006
    Assignee: Westfalia Separator Industry GmbH
    Inventors: Hans-Joachim Beyer, Alfons Monkenbusch, Michael Reichenbach, Michael Müller
  • Patent number: 6955637
    Abstract: In a separation device for separating particles from a liquid, which is present in a container, a centrifugal rotor is rotatable around a vertical rotational axis. The centrifugal rotor has a tubular inlet member, which extends down into liquid to be treated and which upon rotation of the centrifugal rotor forms a pumping member adapted to pump liquid upwardly and into the centrifugal rotor. The rotatable inlet member is surrounded by a non-rotatable wall, a sealing device being adapted to seal between the rotatable inlet member and the non-rotatable wall. Thereby is avoided that liquid is pumped upwardly on the outside of the inlet member. Furthermore, a smallest possible part of the outside of the inlet member can be in contact with liquid, independent of the level of the liquid surface in the container.
    Type: Grant
    Filed: March 21, 2000
    Date of Patent: October 18, 2005
    Assignee: Alfa Laval AB
    Inventors: Jesus Montano, Rolf Ridderstrale, Klaus Hans Dieter Stroucken
  • Patent number: 6824506
    Abstract: A shaped diaphragm as a part of a fluid processing disposable set acting as a centrifuge system rotor. The fluid processing disposable set has a variable-volume chamber and a fluid port. The shaped diaphragm defines a wall of the variable-volume chamber. The chamber is in fluid communication with the fluid port and is defined by a fixed wall and an elastic wall. The elastic wall is formed by the shaped diaphragm. The disposable set may also have a rotary seal coupled to the fluid port and fluidly coupled to the variable-volume chamber. The shaped diaphragm may be convoluted. The convolution may be a single fold and may have a plurality of folds located symmetrically about an axis. The shaped diaphragm may, alternatively, be essentially planar in an unstretched position while varying in thickness along a diaphragm dimension. Centrifuge rotors, systems, and methods for selective harvest of fluid constituents from a whole fluid are detailed.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: November 30, 2004
    Assignee: Haemonetics Corporation
    Inventors: David G. Lamphere, Thomas D. Headley
  • Patent number: 6802804
    Abstract: To clean a relatively heavy liquid from small amounts of relatively light liquid the liquids are first introduced into a container, in which the light liquid is allowed to collect on the surface of the heavy liquid. A surface layer of the liquid body in the container, constituting a mixture of the two liquids, is caused to flow over an overflow outlet member into a collecting chamber. From the collecting chamber the liquid mixture is pumped further into a centrifugal separator, wherein the relatively light liquid is separated from the relatively heavy liquid. According to the invention the liquid mixture is pumped from the collecting chamber to the centrifugal separator through a pumping member, which is connected with a rotor of the centrifugal separator and, thus, rotates therewith.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: October 12, 2004
    Assignee: Alfa Laval AB
    Inventor: Klaus Hans Dieter Stroucken
  • Patent number: 6632191
    Abstract: A system for collecting red blood cells (RBCs) and other blood components that reduces the need for human intervention. A disposable set is provided having a port, an RBC container, a centrifuge rotor having a variable total volume, and a filter, along with tubing connecting the port, the container, the rotor and the filter. A control unit is also provided and includes a spinner in which the rotor may be held, a flow-control arrangement for controlling flow among the various components of the disposable set, and an electronic controller. The whole blood is directed by the flow-control arrangement from the port through the tubing to the rotor. The rotor includes an elastic diaphragm, and the control unit's flow-control arrangement includes a pump or other device for applying a positive and negative pressure to the rotor's elastic diaphragm. The spinner rotates the rotor so as to separate the whole blood into plasma and RBCs.
    Type: Grant
    Filed: March 17, 1999
    Date of Patent: October 14, 2003
    Assignee: Haemonetics Corporation
    Inventors: Thomas D. Headley, Edward T. Powers
  • Patent number: 6626814
    Abstract: A drive unit for a centrifuge rotor of a centrifugal separator is provided that includes a drive shaft, arranged to support the centrifuge rotor and rotatably journalled around an axis (z) of rotation, a casing, which forms an inner space for the drive shaft, a drive motor shaft which is provided outside the casing and connected to the drive shaft by means of a transferring member extending through a passage in the casing, at least one shielding member, which is provided inside the casing in such a manner that the part of the transferring member which is located inside the casing is shielded from the inner space, and wherein the shielding member forms a channel, which extends through the casing and is shielded from the inner space of the casing.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: September 30, 2003
    Assignee: Alfa Laval AB
    Inventor: Jan Setterberg
  • Patent number: 6602179
    Abstract: A rotor for collecting and centrifuging biological fluids in a range of volumes. The rotor includes an elastic impermeable diaphragm which defines at least a portion of a variable-volume processing chamber, where the fluid is centrifuged. The rotor includes a rigid mounting member, to which the diaphragm is mounted and which is held and spun by a chuck. Preferably, this rigid mounting member includes a boundary wall which together with the elastic diaphragm defines the chamber. The boundary wall may be a substantially imperforate circular wall which extends to the periphery of the processing chamber but defining one opening, preferably near the axis of rotation, permitting a conduit or conduits to pass therethrough so as to be in fluid communication with the processing chamber. The rotor may include a separate structure for controlling the flow of liquid out of the chamber into the conduit.
    Type: Grant
    Filed: June 12, 2000
    Date of Patent: August 5, 2003
    Assignee: Haemonetics Corporation
    Inventors: Thomas D. Headley, Edward T. Powers
  • Publication number: 20030125182
    Abstract: A rotor for collecting and centrifuging biological fluids in a range of volumes. The rotor includes an elastic impermeable diaphragm which defines at least a portion of a variable-volume processing chamber, where the fluid is centrifuged. The rotor includes a rigid mounting member, to which the diaphragm is mounted and which is held and spun by a chuck. Preferably, this rigid mounting member includes a boundary wall which together with the elastic diaphragm defines the chamber. The boundary wall may be a substantially imperforate circular wall which extends to the periphery of the processing chamber but defining one opening, preferably near the axis of rotation, permitting a conduit or conduits to pass therethrough so as to be in fluid communication with the processing chamber. The rotor may include a separate structure for controlling the flow of liquid out of the chamber into the conduit.
    Type: Application
    Filed: January 9, 2003
    Publication date: July 3, 2003
    Inventors: Thomas D. Headley, Edward T. Powers
  • Patent number: 6464624
    Abstract: The invention is directed to blood processing method and apparatus utilizing a centrifugation bowl with a filter core disposed within the bowl. The centrifugation bowl includes a rotating bowl body defining an enclosed separation chamber. A generally cylindrical filter core is disposed inside the separation chamber. The filter core includes a filter membrane that is sized to block at least white blood cells, but to allow plasma to pass through. The filter core is generally arranged within the separation chamber such that plasma is forced to pass through the filter core before being removed from the centrifugation bowl. The addition of the filter core provides an efficient, low-cost method for recovering a “purer” plasma fraction from a donor.
    Type: Grant
    Filed: June 12, 2001
    Date of Patent: October 15, 2002
    Assignee: Haemonetics Corporation
    Inventor: Etienne Pages
  • Publication number: 20020142909
    Abstract: A novel centrifuge bowl for processing particles suspended in a fluid is disclosed. The centrifuge bowl includes an annular cavity concentrically located about the rotation axis for suitably separating particles of similar densities but of different diameters. The cavity is preferably configured to have an annular cross sectional area, which is parallel to the rotation axis, that increases from a centrifugal side of the cavity toward a centripetal side of the cavity. This configuration allows to generate an almost rigidly rotating field upon rotation of the centrifuge bowl, which field helps to uniformly disperse Coriolis force throughout the circumference of the cavity to avoid turbulent mixing of the particles. In an alternative embodiment, the cavity is surrounded by an outer cavity for separating particles according to density before processing them through the inner cavity.
    Type: Application
    Filed: March 28, 2001
    Publication date: October 3, 2002
    Inventor: Koichiro Sakota
  • Patent number: 6302836
    Abstract: An ordinary vacuum blood collection tube assembly is rotated about its longitudinal axis to partition a blood sample into serum and formed elements by centrifugation. While still rotating a higher density, immiscible inert liquid is pumped into the vacuum blood collection tube assembly thereby displacing lower density serum towards the axis of rotation and thence out of the vacuum blood collection tube assembly to a serum receiver vessel. A contaminant detector located on the serum delivery conduit controls a 3 way valve to divert contaminants from the removed serum to a waste vessel so only clean serum is delivered to the serum receiver vessel. The serum delivery conduits, serum cannula, and contaminant detector are washed and dried between successive samples to limit sample carryover effects to acceptably low levels.
    Type: Grant
    Filed: September 22, 1999
    Date of Patent: October 16, 2001
    Inventor: Howard L. North, Jr.
  • Patent number: 6228016
    Abstract: A simple but still effective sealing device to separate two openings (4, 5), which are arranged at a distance from each other in the outer casing (3) of a shaft suspension unit (1), which supports a shaft (2) of a centrifugal separator in a bearing (8, 9), the shaft extending axially through at least one opening (4) into a space surrounding the shaft (2) in the outer casing (3). The sealing device is provided with sealing elements (12, 13), one connected to the outer casing (3) and one connected to the shaft (2), which surround the shaft (2) and divide the space in two departments (15, 16) connected to one opening each (4, 5, respectively). The sealing elements form between themselves a narrow gap (14) surrounding the shaft (2), which prevents the flow of gas between the departments (15, 16).
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: May 8, 2001
    Assignee: Alfa Laval AB
    Inventors: Aksel Kristensen, Sven-&angst;ke Nilsson, Jouko Pitkämäki, Carl Peder Öhlander, Robert Sandblom
  • Patent number: 6074335
    Abstract: A rotor for collecting and centrifuging biological fluids in a range of volumes. The rotor includes an elastic impermeable diaphragm which defines at least a portion of a variable-volume processing chamber, where the fluid is centrifuged. The rotor includes a rigid mounting member, to which the diaphragm is mounted and which is held and spun by a chuck. Preferably, this rigid mounting member includes a boundary wall which together with the elastic diaphragm defines the chamber. The boundary wall may be a substantially imperforate circular wall which extends to the periphery of the processing chamber but defining one opening, preferably near the axis of rotation, permitting a conduit or conduits to pass therethrough so as to be in fluid communication with the processing chamber. The rotor may include a separate structure for controlling the flow of liquid out of the chamber into the conduit.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: June 13, 2000
    Assignee: Transfusion Technologies Corporation
    Inventors: Thomas D. Headley, Edward T. Powers