Abstract: An apparatus for removing impurities from a fluid stream includes a support structure, a separator unit rotatably mounted on the support structure, and a motor and/or an array of vanes for rotating the separator unit on the support structure. The separator unit has a longitudinal axis of rotation extending through a longitudinal tube disposed centrally within the separator unit. The longitudinal tube is connected or connectable to a pressurized source of fluid requiring separation, the longitudinal tube having one or more openings for receiving fluid under pressure from the said source and one or more lateral openings for introducing the fluid into the separator unit.

Abstract: A plant for treating drilling muds, which can be installed in building sites for performing excavations or foundations, includes a main mud storage tank containing clean mud ready to be conveyed to the same excavation, a first grizzly screen, a mud processing hopper, at least one cyclone stage provided with at least an inlet in which entering mud to be treated is introduced and with at least a first outlet from which lightened mud (Fa) exits having a lower density than the entering mud, and with at least a second outlet from which a high density mud (Fd) exits, such high density mud having a higher density than the entering mud, and a dewatering screen. Said devices are connected together through pipes in such a way that a mud filled with detritus coming from the excavation is treated in order to be able to be reused once it is returned to the excavation.

Abstract: The invention provides a drilling system for drilling subsea wells from a floating mobile offshore drilling unit (MODU), the system comprising a subsea BOP. The system is distinctive in that the subsea BOP has relative small weight and size, the system includes no marine riser but the system comprises: flexible choke and kill lines arranged between the subsea BOP and the MODU, means for drill string guidance and cleaning, for guiding when inserting or taking out a drill string from the BOP and for drill string cleaning when pulling the drill string out from the BOP, means for controlled leakage of seawater into a recovery funnel arranged below the means for drill string cleaning but above the BOP, and means for return from the recovery funnel to the MODU of drilling fluid and seawater leaked into the recovery funnel.

Abstract: Methods and systems for obtaining platelets are disclosed. Platelets are collected in a pre-determined volume of plasma and a determined amount of a combined storage medium including the pre-determined amount of plasma and a volume of a synthetic additive solution.

Abstract: An oil centrifuge has an integral, rotatably mounted centrifuge rotor and a feed tube connected to the centrifuge rotor. A flow path is provided that supplies oil to the centrifuge rotor. The feed tube is a section of the flow path. The flow path has a throttle point having a reduced throttle cross section that is reduced relative to an upstream flow path cross section of the flow path upstream of the throttle point.

Abstract: A centrifugal rotor includes a support disk and a centrifugal carrier. The centrifugal carrier is assembled within the support disk. The centrifugal carrier includes an arc-shaped body, a sample application chamber, a sample metering chamber, a diluent chamber, a diluent metering chamber, a metering control member and a mixing chamber. The sample metering chamber is communicated with the sample application chamber. The sample metering chamber is positioned radially outward from the sample application chamber. The diluent metering chamber is communicated with the diluent chamber. The diluent metering chamber is positioned radially outward from diluent chamber. The metering control member is slidingly connected within or detachably fixed to the sample metering, chamber or the diluent metering chamber. The mixing chamber is communicated with the diluent metering chamber and the sample metering chamber respectively.

Abstract: Disclosed is a sludge processing system having a centrifugal separator concentrating the sludge and a furnace heat-treating the concentrated sludge. It allows automatic control in which the operational condition of the centrifugal separator operates under optimal conditions according to the operational state of the furnace. The control device sets a variable range of a differential speed between the bowl and screw conveyor of the centrifugal separator, and variably controls the differential speed so concentrated sludge convey torque of the screw conveyor achieves a torque corresponding to a moisture content requested by the furnace within the variable range, when the differential speed varies within a certain previously set range and the concentrated sludge convey torque of the screw conveyor maintains the torque corresponding to the moisture content requested by the furnace for a certain period of time being previously set, changes a control value of the centrifugal force and the torque.

Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: A method of washing blood mixed with undesirable elements not normally found in healthy whole blood to remove the undesirable elements, the method comprising: separating the blood into components according to relative densities of the components with a rotating centrifuge bowl; providing a port through which fluid exits the bowl, the exiting fluid having a concentration of undesirable elements; flowing washing solution into the centrifuge bowl at an initial flow rate; monitoring the fluid exiting the bowl with an optical sensor having an output signal indicative of the composition of the exiting fluid; and increasing and decreasing the flow rate of the wash solution as a function of the output signal.

Abstract: A cleaning apparatus for polluted scrubber fluid from an exhaust gas scrubber fluid loop includes means for bleeding off part of the polluted scrubber fluid from the scrubber fluid loop, a disc stack centrifugal separator for separating a pollutant phase and a cleaned scrubber fluid from said part. The separator includes a rotor enclosing a separation space with a stack of separating discs, a separator inlet extends into the separating space, a first separator outlet for cleaned scrubber fluid extending from said separating space, and a second separator outlet for the pollutant phase extending from the separating space. The cleaning apparatus includes means for conducting the part to the separator inlet, and means for discharging the cleaned scrubber fluid from the first separator outlet, and means for collecting the pollutant phase from the second separator outlet.

Abstract: Device for monitoring and adjusting, in particular for fixing and securing, the radial position of an interface layer in a nozzle centrifuge for separating a light phase having a relatively low density and a heavy phase having a relatively high density from a mixture containing these two liquids and a solid, the nozzle centrifuge including a rotor 1-3 which is rotatable around a rotational axis R and which forms an inlet 9 for said mixture, a separating chamber 7 communicating with said inlet 9 and having a radially inner part 7a and a radially outer part 7b, nozzles 12 at the separating chamber distributed around the rotational axis R for throwing out the heavy phase and the solid, an outlet 13a, 13b, 14 for discharging the light phase, an overflow outlet 19 being radially delimited by a cover or level ring 20 for discharging the heavy phase, and an inlet 9; 25, 26 for supplying additional heavy phase to the centrifuge, characterized in that a sensor 24 is arranged in the flow path of the heavy phase 23 leav

Abstract: An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising a valve design that facilitates loading and unloading of blood bags and associated tubing and bag sets. The valves comprise a rotating head, mounted on a shaft, which assumes a “load” position. The head pivots to an “open” position, which secures the tube in its designated location, but which maintains an open lumen through the tube. When the head is in a “closed” position, blood components cannot flow through the tube. The valve apparatus comprises means for maintaining a constant pressure on the tube and contact with the tube as the tube is melted and sealed.

Abstract: The invention describes a self-powered centrifugal separator comprising a base, a rotor mounted on an operably substantially vertical axis for rotation thereabout by reaction to fluid emission from rotor nozzles therein, a housing mounted on the base and enclosing the rotor, a sump formed in the base below the rotor, a fluid passageway through the base extending from an inlet port to an outlet port and including a diversion port to supply fluid to the interior of the rotor by way of the rotation axis, a drain passage in the base for draining fluid from the sump to the fluid passageway, and a venturi arrangement provided in the fluid passageway in the base to develop suction pressure to draw fluid from the drainage passage into the fluid passageway, whereas a spring loaded valve body is provided in the fluid passageway, said body being configured and arranged to shut off supply of fluid to the interior of the rotor when pressure of fluid entering the inlet port falls below a predetermined minimum pressure valu

Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Abstract: The present invention relates to methods, devices and systems for separation and concentration of particles from liquid and fluid samples. In some embodiments, the separation/concentration is achieved by sequential centrifugation steps. In particular, one aspect of the invention relates to a separation/concentration device which comprises at least a first chamber (101) and a second chamber (103) connected by a first valve (111), whereby operation of the first valve controls the material transfer from the first chamber to the second chamber. In some embodiments, valve operation can be manually, semi-manually or automatically. Other aspects of the invention relate to single- or multi-chambered separation/concentrator devices, and methods and systems for use. Other aspects of the invention relate to devices for operation of the valves, e.g., semi-manual actuation devices, and automatic inertial activation devices and mechanical actuation devices present in purpose-built centrifuges.

Abstract: A system for separating a sample and collecting the separated sample. The system includes an ultracentrifuge having a cylindrical rotor. The system includes a gradient delivery assembly for delivering a gradient solution to the ultracentrifuge rotor, and a sample delivery assembly for delivering the solution containing the sample to the ultracentrifuge rotor. The system includes a fraction collection assembly for collecting discrete volumes of the separated sample. The system includes a processor for controlling operation of the ultracentrifuge, as well as the gradient delivery assembly, the sample delivery assembly, and/or the fraction collection assembly.

Abstract: The invention describes a self-powered centrifugal separator comprising a base, a rotor mounted on an operably substantially vertical axis for rotation thereabout by reaction to fluid emission from rotor nozzles therein, a housing mounted on the base and enclosing the rotor, a sump formed in the base below the rotor, a fluid passageway through the base extending from an inlet port to an outlet port and including a diversion port to supply fluid to the interior of the rotor by way of the rotation axis, a drain passage in the base for draining fluid from the sump to the fluid passageway, and a venturi arrangement provided in the fluid passageway in the base to develop suction pressure to draw fluid from the drainage passage into the fluid passageway, whereas a spring loaded valve body is provided in the fluid passageway, said body being configured and arranged to shut off supply of fluid to the interior of the rotor when pressure of fluid entering the inlet port falls below a predetermined minimum pressure valu

Abstract: A centrifuge includes a rotational mechanism, a housing, a rotating feed pipe and a basket. The housing includes at least one side and defines an interior volume. The basket is positioned in the interior volume of the housing and is operatively coupled to the rotational mechanism such that rotation of the rotational mechanism is imparted to the basket. The rotating feed pipe extends into the basket through a pipe support positioned over the basket. The rotating feed pipe includes a nozzle operable to direct a flow of liquids, solids or combinations thereof onto a sidewall of the basket. The rotating feed pipe is operable to rotate from a first position towards a second position thereby increasing the distance between the nozzle and the sidewall and varying an angular orientation of the nozzle with respect to a normal to the sidewall.

Abstract: The invention relates to a method and a device for separating blood using a centrifuge in order to obtain different blood fractions. The aim of the invention is to eliminate the risk of contamination during the supply of blood and the removal of blood fractions. To achieve this, the separation container is filled with blood via a feed connection that can be aseptically connected to the container, the relevant blood fraction is removed from the separation container via a removal connection that can be aseptically connected to the container and both the feed device and the removal device form a respective closed system during the sterile connection to the separation container. The separation container (4) has at least one feed connection (5, 6) that can be aseptically connected to the container and at least one removal connection (7) that can be aseptically connected to the container, to which hermetically sealed feed and removal devices (8, 9, 10) can be aseptically attached in a sterile manner.

Abstract: An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising an asymmetrical junction or manifold in the blood bag and tubing set inhibits errors when the bags and tubes are loaded into the device.

Abstract: An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising a valve design that facilitates loading and unloading of blood bags and associated tubing and bag sets. The valves comprise a rotating head, mounted on a shaft, which assumes a “load” position. The head pivots to an “open” position, which secures the tube in its designated location, but which maintains an open lumen through the tube. When the head is in a “closed” position, blood components cannot flow through the tube. The valve apparatus comprises means for maintaining a constant pressure on the tube and contact with the tube as the tube is melted and sealed.

Abstract: A dual feed centrifuge system for separating solids from fluids in a drilling mud, the centrifuge system including: a bowl; a screw conveyor rotatably mounted within the bowl; a first feed pipe mounted within the screw conveyor for feeding a drilling mud through a first feed port in a wall of the screw conveyor to a first annular space between the bowl and the wall of the screw conveyor; and a second feed pipe mounted within the screw conveyor for feeding a drilling mud through a second feed port in the wall of the screw conveyor to a second annular space between the bowl and the wall of the screw conveyor. The multiple feed ports may allow the centrifuge to operate more efficiently with both weighted and unweighted drilling fluids.

Abstract: Method for supervising a centrifugal separator with a separating chamber, a radially inner outlet connected to the separating chamber and to an outlet conduit, with a flow detector disposed in the outlet conduit and adapted to detecting a flow in the outlet conduit, and an intermittently openable radially outer outlet connected to the separating chamber. In order reliably and easily to supervise the intermittent discharge of the centrifugal separator, the pressure is measured by a sensor disposed in a portion of the centrifugal separator which is pressure-transmittingly connected to a central portion of the interior of the rotor. If the supervision unit does not detect a pressure drop pulse from the sensor within a predetermined period of time from when an intermittent discharge is initiated, an alarm signal is emitted.

Abstract: A solid-bowl screw centrifuge includes a rotatable drum having a horizontal axis of rotation, which drum surrounds a centrifuging space. Further included is a screw which is arranged within the drum, the screw being rotatable at a different speed relative to the drum. Further included is at least one liquid discharge sealed from its surroundings and at least one solid discharge in a tapering region of the drum. Also included is an immersion disk on the screw which disk lies between a liquid feed and the solid discharge and divides the centrifuging space into a discharge space between the immersion disk and the solid discharge, and a separation space between the immersion disk and the liquid discharge. The centrifuge includes a device for charging the separation space with a gas. A process for operating for the solid-bowl centrifuge is also disclosed.

Abstract: The present invention relates to an apparatus for separating a fluid flow, the fluid flow comprising lighter and heavier fractions to be separated from each other, the apparatus comprising at least one inlet (22) and at least two outlets (5, 23), the apparatus further comprising a rotary centrifuge device (1), the lighter fractions being carried further on through one of the outlets (23) and the heavier fractions being carried through the other one of the outlets (5). The invention is characterized in that a spin-up assembly (17) is arranged upstream of the rotary centrifuge device (1), the spin-up assembly (17) being configured in such a manner that the fluid flow entering the rotating cylinder (1) is imparted a rotational movement, the rotational velocity of the cylinder (1) being adjustable so that the relative velocity difference between the rotating movement of the fluid flow and the rotational velocity of the centrifuge device (1) is optimal in terms of separation.

Abstract: A centrifuge includes a housing that defines a fluid inlet port to supply fluid to the centrifuge and an axle cavity fluidly coupled to the fluid inlet port. A bearing is received in the axle cavity. A check valve is disposed in the axle cavity to minimize tampering, and the check valve is configured to control flow of the fluid from the inlet port. A rotor is configured to separate particulate matter from the fluid. The rotor includes an axle rotatably received in the bearing, and the axle defines a fluid passage to supply the fluid to the rotor. The check valve is normally biased towards a closed position where the flow of the fluid is shutoff. The axle is configured to open the check valve when the axle is received in the bearing.

Abstract: A centrifuge apparatus for processing blood comprising a bottom spring-loaded support plate; a top support plate; an axial inlet/outlet for blood to be processed and processed components of the blood, the axial inlet/outlet being attached to the top support plate by a rotating seal assembly; a variable volume separation chamber mounted between the bottom support plate and the top support plate, the variable volume separation chamber being fluidly connected to the axial inlet/outlet; a pump fluidly connected to the axial inlet/outlet; and a rotary drive unit attached to the bottom support plate. The top support plate is fixed vertically and the bottom spring-loaded support plate is mounted on springs that maintain pressure on the variable volume separation chamber and allow the bottom support plate to move vertically.

Abstract: An apparatus comprises an inlet to convey a first fluid comprising first and second components having different density into a rotating chamber such that an interface forms between at least portions of such components at a first location. At least one outlet removes at least one of the first and second components. A controller is adapted to introduce the first fluid and is operable to move the interface from the first location to a second location and to move the interface from the second location in a direction toward the first location and to return the interface to the second location. The controller is operable to determine a flow rate of the first or second component based, at least in part, on the time interval between when the interface moves from and returns to the second location. At least one sensing assembly is adapted to sense the location of the interface.

Abstract: The present disclosure relates to a centrifuge having a vertical axis of rotation, and including a centrifugal drum having a feeding tube for material to be centrifuged, outlet nozzles, and an emergency off system connected in front of the centrifugal drum. The emergency off system includes a feeding system feeding particles into the centrifugal drum. The present disclosure also relates to a method of implementing an emergency off system of the centrifuge. The method steps include: providing an emergency off signal; feeding the particles into the centrifugal drum in response to the emergency off signal; and, wherein the particles plug the outlet nozzles.

Abstract: A centrifuge for the purification of lubricating oil of an internal-combustion engine is provided which includes a housing with a removable cover, a housing-fixed shaft arranged in the housing and a centrifuge rotor which is rotatably mounted on the shaft and is replaceable. The shaft is hollow at least in its lower part and forms in its hollow inside a section of a lubricating oil supply canal, which canal is in flow connection with an inside of the centrifuge rotor mounted on the shaft over at least one orifice opening. The centrifuge also includes an adjustable valve plug arranged at the shaft and arranged to be held in an open position by the centrifuge rotor. The valve plug releases the orifice opening in the open position. The valve plug is also arranged to be transferred into a closing position and held in the closing position by a force created by at least one of a pressure of the lubricating oil and by a preloading component if the centrifuge rotor is missing.

Abstract: The invention disclosed is control equipment for use with a nozzle centrifuge for separating a light phase liquid, a heavy phase liquid, and/or solids from a mixture thereof wherein the separated heavy phase and solids are continuously removed through nozzles that are arranged at the periphery of the rotor of the nozzle centrifuge. Separated light phase liquid is discharged through a central outlet in the rotor. Through a space in the rotor, which communicates with the radially outer part of the rotor separating chamber, liquid may either be supplied under pressure to the rotor or be discharged from the rotor far maintaining an interface layer formed in the separating chamber between separated light and heavy phases. A supply device and a discharge device are adapted to supply to the rotor and discharge from the rotor, respectively, only so much liquid as is required for the purpose.

Abstract: An indication device indicates an undesired operation condition of a centrifugal separator and comprises an inlet valve situated in a supply conduit to the separator, and an outlet valve situated in an outlet conduit from the separator. During normal operation of the separator the valves are adjusted in open normal valve positions for passing normal flows through the supply and outlet conduits. A control unit is adapted to activate a signal generator to generate an error signal in response to a pressure sensor if the pressure sensor during a predetermined period of time during operation of the separator senses a course of pressure change in the outlet conduit different from an expected normal course of pressure change, when the inlet and outlet valves during predetermined period of time are adjusted in valve positions which at least substantially decreases the flows in the supply and outlet conduits from the normal flows.

Abstract: A centrifuge for separating particulate matter from a fluid includes a housing having a base portion defining a fluid inlet, a rotor subassembly in the housing and including a centertube and a shaft. The shaft defines a plurality of fluid outlet ports and a fluid passageway in flow communication therewith. The fluid passageway communicates with the fluid inlet such that oil delivered to the centrifuge flows through a portion of the centrifuge shaft and exits from the fluid outlet ports. Press fit into the centertube is a baffle sleeve which is initially positioned so as to cover the fluid outlet ports when the baffle sleeve is in a first position. The baffle sleeve is movable with the rotor subassembly to a second position where the plurality of fluid outlet ports are uncovered.

Abstract: A centrifuge, particularly a separator (1) with a vertical axis of rotation, having a centrifugal drum (2) which is equipped with a feeding tube (4) for material to be centrifuged as well as with outlet nozzles, an emergency off system being connected in front of the centrifugal drum (2), is characterized in that the emergency off system has a feeding system (17) for particles, particularly balls (16), into the centrifugal drum. In the case of a method of implementing an emergency off function of a centrifuge, balls (16), which plug the outlet nozzles, are correspondingly guided into the centrifugal drum (2) in an emergency off case.

Abstract: Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Abstract: An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into container adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the container to control the operation of valves directing the collection of each component. Each component may then be separated into its own storage container.

Abstract: Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Abstract: The claimed invention relates to a method and a device for processing blood concentrate products before they are exposed to a continued process for extracting those remaining medicinally interesting sub-components. The appropriate pre-processing, in relation to the invention, primarily entails a mechanically powered resolution of the viscous flowing concentrate products in a diluting solution for the adaptation of the total products for a renewed centrifuging.

Abstract: A fluid mixture containing a heavy component and a light component is separated by feeding the fluid mixture into a vessel. The vessel includes a light component outlet regulated by a first valve and a heavy component outlet regulated by a second valve. The vessel is rotated about a rotational axis extending through the vessel as the liquid-liquid mixture is feed into the chamber such that the heavy component collects toward at least a portion of the peripheral wall of the vessel radially outward from the rotational axis and the lighter component collects toward the rotational axis. The first valve is set such that the light component exits therethrough at a first pressure. The second valve is set such that the heavy component exits therethrough at a second pressure, the second pressure being different than the first pressure.

Abstract: An apparatus and method are provided for separating components of a fluid or particles. A separation vessel having a barrier dam is provided to initially separate an intermediate density components of a fluid, and a fluid chamber is provided to further separate these intermediate density components by forming an elutriative field or saturated fluidized particle bed. The separation vessel includes a shield for limiting flow into the fluid chamber of relatively high density substances, such as red blood cells. The separation vessel also includes a trap dam with a smooth, gradually sloped downstream section for reducing mixing of substances. Structure is also provided for adding additional plasma to platelets and plasma flowing from the fluid chamber. The system reduces clumping of platelets by limiting contact between the platelets and walls of the separation vessel.

Abstract: A system and method for controlling a centrifuge which receives a mixture of liquid and solid particles and separates the liquid from the solid particles. A bowl, along with a conveyor extending inside the bowl, are rotated and the speed of, and the torque applied to, the bowl and the conveyor are detected and corresponding output signals are generated. A variable speed drive pump is provided for pumping the flow of the mixture to the centrifuge. A computer responds to the output signals and controls the speed of the bowl and the conveyor as well as the operation of the pump to attain predetermined optimum operating conditions of the centrifuge.

Abstract: Apparatus for separating a biological component from a biological fluid are disclosed. The apparatus includes a chamber for receiving a biological fluid including a biological component, and a rotor for creating a centrifugal field within the chamber. A source of particles may be included wherein the particles have a binding site for selectively binding to the biological component. The particles may be aseptically introduced into the chamber. The apparatus may withdraw whole blood from a donor, separate the whole blood to obtain a target cell population and return a selected one of either the target cell population or at least a portion of the whole blood remainder to the donor or patient. A disposable separation inset for use in conjunction with a rotatable separation device such as the apparatus described above may also be provided.

Abstract: An apparatus and method are disclosed for filtering or separating particles. The apparatus has a centrifuge rotor rotatable about an axis of rotation. A fluid chamber rotates with the rotor. A substance is supplied to the inlet of the chamber. A saturated fluidized bed of first particles forms within the fluid chamber and obstructs flow of second particles through the chamber. Additive substances alter sedimentation velocity of the first particles to modify the filtration characteristics of the saturated fluidized bed.

Abstract: Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Abstract: An apparatus and method are disclosed for filtering or separating particles. The apparatus has a motor coupled to a centrifuge rotor rotatable about an axis of rotation. A fluid chamber rotates with the rotor. A substance is supplied to the inlet of the chamber. At least one of the motor and the substance supply are controlled to maintain a saturated fluidized bed of first particles within the fluid chamber while causing second particles to be retained in the chamber.

Abstract: A liquid cleaning system, which includes a barrier type filter having a back-flush arrangement for recovering filter contaminants from the back-flushed liquid which is available only at a low, not necessarily consistent, rate, includes a fluid-powered centrifugal cleaner which, in addition to the normal shaft-mounted rotor through which liquid is passed to separate contaminants centrifugally due to rotor speed, includes fluid drive means in the form of fluid reaction drive nozzles supplied with pumped liquid from the system as a drive fluid to rotate the rotor at a speed above the minimum to effect centrifugal separation of the contaminants from the back-flushed liquid in the rotor and accumulation of the outlet of the rotor. The spent drive fluid mixes with the cleaned back-flushed liquid in a discharge region and both may be re-used in the system.

Abstract: A system, method and computer program for controlling a centrifuge which receives a mixture of liquid and solid particles and separates the liquid from the solid particles. A bowl, along with a conveyor extending inside the bowl, are rotated at different speeds and the speed of, and the torque applied to, the bowl and the conveyor are detected and corresponding output signals are generated. A meter is provided for metering the flow of the mixture to the centrifuge and generating corresponding output signals. A computer responds to instructions from computer programs and controls the speed of the bowl and the conveyor as well as the flow of the mixture and a diluting agent to the centrifuge in response to the output signals in a manner to attain predetermined predetermined optimum operating conditions of the centrifuge.