Miscellaneous Patents (Class 494/85)
  • Patent number: 8795143
    Abstract: A spinning force system and methods of operation are provided for measuring a characteristic of a sample. The system includes a detection module having a light source for illuminating the sample and an objective being aligned to the light source to define a light path for producing an image of the sample. A rotor is mechanically coupled to the detection module and configured to rotate the light path for applying a force to the sample. The force may include a centrifugal force and other forms of force (such as a viscous drag force) resulted from the rotation. In some examples, the force is applied in a direction that is not parallel to a surface of the sample.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: August 5, 2014
    Assignee: President and Fellows of Harvard College
    Inventors: Wesley Philip Wong, Kenneth Anders Halvorsen
  • Publication number: 20140148325
    Abstract: According to one exemplary embodiment of the present invention, a method of centrifuging a mixture using a syringe which has a nozzle at one end, comprises the steps of taking the mixture in the syringe, first centrifuging the mixture in the syringe, discharging one part of the mixture which is adjacent to the nozzle after the first centrifuging, second centrifuging the mixture in the syringe after reversing the syringe, and discharging another part of the mixture which is adjacent to the nozzle after the second centrifuging.
    Type: Application
    Filed: October 12, 2011
    Publication date: May 29, 2014
    Applicant: SNU R & DB FOUNDATION
    Inventors: Chris Hyunchul Jo, Sue Shin, Kang Sup Yoon
  • Patent number: 8678988
    Abstract: A centrifuge opening tool has a frame that securely holds a centrifuge drum therein. An upright tube is mounted to the frame and a brake band is rotatably secured to the upright tube. When the brake band is tightened, the centrifuge drum is securely held in place. A ring gear is secured to a lock ring. The lock ring is part of the centrifuge drum and is removable to allow access to the interior therein. A drive gear meshes with the ring gear and increases the mechanical advantage allowing a user to apply the force needed to open the lock ring even when it has been extremely compressed. A spanner wrench is placed on a drive shaft that is connected to the drive gear. Engagement pins are used to mechanically couple the gear ring and lock ring together.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: March 25, 2014
    Inventor: Thomas Lahmann
  • Patent number: 8491454
    Abstract: A spinning force system and methods of operation are provided for measuring a characteristic of a sample. The system includes a detection module having a light source for illuminating the sample and an objective being aligned to the light source to define a light path for producing an image of the sample. A rotor is mechanically coupled to the detection module and configured to rotate the light path for applying a force to the sample. The force may include a centrifugal force and other forms of force (such as a viscous drag force) resulted from the rotation. In some examples, the force is applied in a direction that is not parallel to a surface of the sample.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: July 23, 2013
    Assignee: President and Fellows of Harvard College
    Inventors: Wesley P. Wong, Kenneth A. Halvorsen
  • Patent number: 8226826
    Abstract: Disclosed is a disk based system for separating at least two types of particulates contained in a sample fluid. The system includes a disk-like carrier board and a magnetic attraction unit. The disk-like carrier board forms at least one flow channel structure, which includes an inner reservoir, at least one separation chamber, and at least one outer reservoir arranged in sequence from a geometric center of the disk-like carrier board to an outer circumferential rim of the disk-like carrier board. A method of separation carried out with the system includes introducing the sample fluid into the inner reservoir and then rotating the disk-like carrier board to induce a centrifugal force. The sample fluid contains particulates that are labeled with immunomagnetic beads and the labeled particulates are attracted by the magnetic force generated by the magnetic attraction unit to retain in the inner reservoir or the separation chamber.
    Type: Grant
    Filed: June 25, 2009
    Date of Patent: July 24, 2012
    Assignee: National Taiwan University
    Inventors: Andrew M. Wo, Chen-Lin Chen, Ken-Chao Chen, Yu-Cheng Pan
  • Patent number: 8177072
    Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: May 15, 2012
    Assignee: ThermoGenesis Corp.
    Inventors: John R. Chapman, Vijay Kumar, Brian K. Cinquini, Phillip D. Kingsley
  • Patent number: 8101138
    Abstract: A centrifugal micro fluidic system and a centrifugal magnetic position control device used in the centrifugal micro fluidic system for controlling the position of magnetic beads are provided. The centrifugal micro fluidic system comprising, a rotatable platform; a micro fluidic structure which is disposed in the platform; and a plurality of objects which include functional groups on surfaces thereof so as to capture a target material from the fluid and carry the target material while being suspended in and separated from the fluid in the micro fluidic structure, wherein the movements of the objects are controlled by a force affecting the objects differently compared to the force's effect on the fluid. When the objects are made of a magnetic material, the force may be a magnetic force applied by the centrifugal magnetic position control device.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: January 24, 2012
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jeong-gun Lee, Yoon-kyoung Cho, Beom-seok Lee, Jong-myeon Park
  • Patent number: 7954646
    Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: June 7, 2011
    Assignee: Biomet Biologics, LLC
    Inventors: Michael D. Leach, Jennifer E. Woodell-May, Joel C. Higgins, Brandon Miller
  • Patent number: 7914753
    Abstract: An analytical system includes a working fluid, a uniform dividing unit and a separating unit. The working fluid includes a first component and a second component with different characteristics. The uniform dividing unit is utilized to uniformly divide the working fluid and relatively rotated with respect to a reference axis. Under a capillarity force as well as the result of Coriolis force and siphon force, the first component can be separated from the second component by the separating unit.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: March 29, 2011
    Assignee: Industrial Technology Research Institute
    Inventors: Chung-Hsien Tsai, Chin-Tai Tseng, Chien-Chih Huang, Wen-Pin Hsieh, Hsiao-Chung Tsai, Cheng-Yu Ko
  • Patent number: 7867159
    Abstract: A centrifugal method, and corresponding system, for processing blood to collect platelet rich plasma. A separation chamber is filled with blood from a fill syringe by rotating the separation chamber at a fill rotation rate and pumping the blood from the fill syringe. A soft spin is used to initially separate red blood cells from platelets by spinning the separation chamber at a soft spin rate. A percentage of the blood is drawn from the separation chamber back into the fill syringe to remove separated red blood cells. A second portion of the separated blood is drawn from the separation chamber until a red blood cell/platelet interface is detected. A hard spin is performed by spinning the separation chamber at a higher rate and connecting tubing is cleared of red blood cells by drawing a predetermined clearing volume. The platelet rich plasma is then collected in the collection syringe.
    Type: Grant
    Filed: June 4, 2007
    Date of Patent: January 11, 2011
    Assignee: Arteriocyte Medical Systems, Inc.
    Inventors: Victor D. Dolecek, Gary L. Berg, Kenneth E. Merte, David Malcolm, Kevin D. McIntosh, Vitaly G. Sitko
  • Publication number: 20100323870
    Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Application
    Filed: August 11, 2010
    Publication date: December 23, 2010
    Applicant: Biomet Biologics, LLC
    Inventors: Michael D. Leach, Jennifer E. Woodell-May, Joel C. Higgins, Brandon Miller
  • Patent number: 7645377
    Abstract: A system for transferring blood product between a blood storage bag and a processing bag. The system includes an airtight containment chamber for supporting therein one or more blood storage bags. A door is provided for access to the chamber and there is included an airtight fixture that allows tubing from the blood storage bag to exit the chamber. A fluid pump is coupled to the containment chamber for establishing either pressure or vacuum within the containment chamber. A controller controls the air pump to, in turn, control the transfer of a blood product.
    Type: Grant
    Filed: January 6, 2006
    Date of Patent: January 12, 2010
    Assignee: ZymeQuest, Inc.
    Inventor: Keith Rosiello
  • Patent number: 7547272
    Abstract: A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: June 16, 2009
    Assignee: Harvest Technologies Corporation
    Inventors: James R. Ellsworth, Steven F. Levesque
  • Patent number: 7531148
    Abstract: A two-tube centrifuge separates light material and heavy material from an input mixture. A hollow drive shaft rotates a central body member about an axis of rotation. Two hollow arm assemblies, each having circular cross-section, are mounted on diametrically opposite sides of the central body. Each arm assembly includes an outer housing tube, an intermediate tube, and an inner tube that is longer than the intermediate tube. An end cap having a removable plug is mounted on the outer end of the housing-tube of each arm assembly. The inner ends of all three tubes are mechanically interlocked in a manner to cantilever mount the inner and intermediate tubes to the central-body with their outer ends spaced from the internal surface of the end cap. An input-mixture path extends through the hollow drive shaft, through the central-body, and into a cylindrical space between the inner and intermediate tubes of each arm assembly.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: May 12, 2009
    Assignee: ERTH Technologies, Inc.
    Inventors: Paul J. Cornay, Ernest Peter Tovani, Gary Matzen
  • Patent number: 7442315
    Abstract: The present invention relates to a separation device notably for a flow-force fractionation of suspended substances in a liquid carrier, said separation device comprising a separation channel and a counter-channel. The object of the present invention is mainly the separation of living cells, preferably of human origin, in particular cells which are found in body fluids.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: October 28, 2008
    Assignee: Universite de Limoges
    Inventors: Philippe Cardot, Serge Battu, Robert Sarrazin
  • Patent number: 7189331
    Abstract: An adapter for use with a centrifuge. Features of the adapter allow for less friction during extraction of the adapter and separation efficiency by preventing disturbances to the separated materials. In addition, the adapter includes features that support the walls of a sample container and prevent force from damaging the sample container during a centrifuge separation procedure.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: March 13, 2007
    Assignee: Beckman Coulter, Inc.
    Inventors: Patrick Q. Moore, Christopher L. Stewart
  • Patent number: 7118522
    Abstract: An adapter for use with a centrifuge. Features of the adapter allow for less friction during extraction of the adapter and separation efficiency by preventing disturbances to the separated materials. In addition, the adapter includes features that support the walls of a sample container and prevent force from damaging the sample container during a centrifuge separation procedure.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: October 10, 2006
    Assignee: Beckman Coulter, Inc.
    Inventors: Patrick Q. Moore, Christopher L. Stewart, TenLin S. Tsai
  • Patent number: 7077273
    Abstract: A separator disk (4) for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: July 18, 2006
    Assignee: Harvest Technologies Corporation
    Inventors: James R. Ellsworth, Steven F. Levesque
  • Patent number: 7011742
    Abstract: A system for transferring blood product between a blood storage bag and a processing bag. The system includes an airtight containment chamber for supporting therein one or more blood storage bags. A door is provided for access to the chamber and there is included an airtight fixture that allows tubing from the blood storage bag to exit the chamber. A fluid pump is coupled to the containment chamber for establishing either pressure or vacuum within the containment chamber. A controller controls the air pump to, in turn, control the transfer of a blood product.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: March 14, 2006
    Assignee: ZymeQuest, Inc.
    Inventor: Keith Rosiello
  • Patent number: 6936122
    Abstract: An assembly for supporting a fiber optic termination or connector in a centrifuge and comprising a cylindrical body member having a top portion adapted to receive the ferrule body portion of a fiber optic termination or connector and a bottom portion for receiving a cylindrical piston/sealing unit. The piston portion of the piston/sealing unit includes a compressible tip which is adapted to a butt up against the outer end of the ferrule body portion of the fiber optic termination or connector. A cylindrical end cap fits over the upper end of the body member for holding the fiber optic termination in place on the body member and causing a seal to be formed between the termination or connector and the upper portion of the body member adjacent the compressible tip of the plunger. The parts, when fitted together, are placed in a centrifuge which is operated for a predetermined spin cycle, so as to cause any bubbles in the uncured liquid adhesive to be vented outwardly from the termination through the end cap.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: August 30, 2005
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventor: John R. Kolasinski
  • Patent number: 6709412
    Abstract: Systems and methods separate blood cells from whole blood and pump the separated blood cells through an in-line leukofilter to a blood cell storage container. The leukofilter has a filtration medium enclosed within a flexile housing. The systems and methods employ a fixture to restrain expansion of the flexible filter housing during operation of the pump. The fixture has a bracket to enable its releasable attachment to the blood processing device employed to carry out the separation process.
    Type: Grant
    Filed: October 13, 2001
    Date of Patent: March 23, 2004
    Assignee: Baxter International Inc.
    Inventors: Mark Vandlik, Michael J Kast, Kelly B Smith
  • Patent number: 6432034
    Abstract: A locking ring for joining a first and second of a rotor in a centrifugal separator, the first rotor part having a cylindrical end portion, and the second part having an annular flange. A locking ring is arranged to be positioned into a recess and via two radially outer contact surfaces to abut against the end portion and via inner contact surfaces to abut against the flange. The locking ring extends substantially a complete revolution around the rotational axis with two end surfaces turned towards one another and being so formed out of a single piece of resilient material that in an unloaded condition is substantially annular with an outer diameter, is at least as large as the outer radius of the recess, the contact surfaces being are so located that they in every axial section around the rotational axis have a middle point, in which the contact surface have a direction of normalcy, which is the for all contact surfaces.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: August 13, 2002
    Assignee: Alfa Laval AB
    Inventors: Sven Hedin, Kjell Lintenstedt, Toini Salmi
  • Patent number: 6428700
    Abstract: A centrifuge filter for removing soot from engine oil. The centrifuge filter includes a rotor adapted to be rotated inside a centrifuge housing by an electric motor or other means. The rotor preferably includes a reusable aluminum support casing and a disposable plastic cartridge. The plastic cartridge includes a trap with partition walls to prevent wave formation in the rotating liquid contained in the trap. The cartridge includes an annular inlet through its top end, a winding flow path through the cartridge and an outlet at the bottom enc. The centrifuge housing includes an isolated sealed rotor chamber. Using the venturi effect, air is evacuated from the rotor chamber to provide a partial vacuum to reduce air drag on the rotor. Resilient rubber vibration isolators are used to reduce vibrations and engine induced shock loads from reaching the rotating element. A side oil inlet is provided in the cartridge to receive unfiltered oil at a location offset from the axis of rotation.
    Type: Grant
    Filed: September 6, 2000
    Date of Patent: August 6, 2002
    Assignee: Baldwin Filters, Inc.
    Inventors: Gene W. Brown, Steven J. Merritt
  • Patent number: 6398705
    Abstract: The method of rapidly separating plasma or serum from red blood cells comprising the steps of mounting a pair of spaced apart tubes coaxially related to one another head-to-head with a sharp-ended hollow needle disposed generally along the tube axes and between them, arranging the tubes in a vertical position one above the other in a centrifuge with the tubes closed with self-sealing stoppers, providing a partial vacuum in the upper tube, rotating the tubes at high speed about an axis parallel to and spaced from the axis of the tubes and needle, after separation of the red blood cells from the plasma and serum causing the tubes while still being rotated to be moved relative to one another such as to cause the needle to enter both tubes through the stoppers, separating the tubes while still being rotated by the centrifuge whereby to remove the needle from both tubes.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: June 4, 2002
    Inventors: Manfred Grumberg, Oren Zinder, James W. Winkelman, Jacob Schreibman
  • Publication number: 20020061807
    Abstract: A float is used for preparing a density gradient in a parallel-walled vessel. The float has an outer peripheral surface that has a diameter smaller than an inner diameter of an inner surface of the vessel. With the float placed inside the vessel a liquid is introduced onto the float such that the liquid flows around the float between the float and the inner wall of the vessel. The shape and configuration of the float slows the velocity of the liquid such that there is only laminar flow as the liquid contacts other liquid below the float. Elimination of turbulent flow prevents mixing of different liquid introduced into the same vessel thereby forming layers of fluid. Preferably, the vessel is a centrifuge tube. In one embodiment, the outer diameter of the float is large enough to cause capillary action between the float and the inner surface of the centrifuge tube to force liquid to remain between the float and the inner surface of the centrifuge tube.
    Type: Application
    Filed: January 11, 2002
    Publication date: May 23, 2002
    Inventor: Norman G. Anderson
  • Publication number: 20020042335
    Abstract: A float is used for preparing a density gradient in a parallel-walled vessel. The float has an outer peripheral surface that has a diameter smaller than an inner diameter of an inner surface of the vessel. With the float placed inside the vessel, a liquid is introduced onto the float such that the liquid flows around the float, between the float and the inner wall of the vessel. The shape and configuration of the float slows the velocity of the liquid such that there is only laminar flow as the liquid contacts other liquid below the float. Elimination of turbulent flow prevents mixing of different liquid introduced into the same vessel, thereby forming layers of fluid. Preferably, the vessel is a centrifuge tube. In one embodiment, the outer diameter of the float is large enough to cause capillary action between the float and the inner surface of the centrifuge tube to force liquid to remain between the float and the inner surface of the centrifuge tube.
    Type: Application
    Filed: April 18, 2001
    Publication date: April 11, 2002
    Inventor: Norman G. Anderson
  • Publication number: 20020007895
    Abstract: An assembly for supporting a fiber optic termination or connector in a centrifuge and comprising a cylindrical body member having a top portion adapted to receive the ferrule body portion of a fiber optic termination or connector and a bottom portion for receiving a cylindrical piston/sealing unit. The piston portion of the piston/sealing unit includes a compressible tip which is adapted to a butt up against the outer end of the ferrule body portion of the fiber optic termination or connector. A cylindrical end cap fits over the upper end of the body member for holding the fiber optic termination in place on the body member and causing a seal to be formed between the termination or connector and the upper portion of the body member adjacent the compressible tip of the plunger. The parts, when fitted together, are placed in a centrifuge which is operated for a predetermined spin cycle, so as to cause any bubbles in the uncured liquid adhesive to be vented outwardly from the termination through the end cap.
    Type: Application
    Filed: August 31, 2001
    Publication date: January 24, 2002
    Inventor: John R. Kolasinski
  • Publication number: 20010031689
    Abstract: A float is used for preparing a density gradient in a parallel-walled vessel. The float has an outer peripheral surface that has a diameter smaller than an inner diameter of an inner surface of the vessel. With the float placed inside the vessel a liquid is introduced onto the float such that the liquid flows around the float between the float and the inner wall of the vessel. The shape and configuration of the float slows the velocity of the liquid such that there is only laminar flow as the liquid contacts other liquid below the float. Elimination of turbulent flow prevents mixing of different liquid introduced into the same vessel thereby forming layers of fluid. Preferably, the vessel is a centrifuge tube. In one embodiment, the outer diameter of the float is large enough to cause capillary action between the float and the inner surface of the centrifuge tube to force liquid to remain between the float and the inner surface of the centrifuge tube.
    Type: Application
    Filed: April 18, 2001
    Publication date: October 18, 2001
    Inventor: Norman G. Anderson
  • Publication number: 20010031688
    Abstract: A float is used for preparing a density gradient in a parallel-walled vessel. The float has an outer peripheral surface that has a diameter smaller than an inner diameter of an inner surface of the vessel. With the float placed inside the vessel a liquid is introduced onto the float such that the liquid flows around the float between the float and the inner wall of the vessel. The shape and configuration of the float slows the velocity of the liquid such that there is only laminar flow as the liquid contacts other liquid below the float. Elimination of turbulent flow prevents mixing of different liquid introduced into the same vessel thereby forming layers of fluid. Preferably, the vessel is a centrifuge tube. In one embodiment, the outer diameter of the float is large enough to cause capillary action between the float and the inner surface of the centrifuge tube to force liquid to remain between the float and the inner surface of the centrifuge tube.
    Type: Application
    Filed: April 18, 2001
    Publication date: October 18, 2001
    Inventor: Norman G. Anderson
  • Patent number: 6287404
    Abstract: An assembly for supporting a fiber optic termination or connector in a centrifuge and comprising a cylindrical body member having a top portion adapted to receive the ferrule body portion of a fiber optic termination or connector and a bottom portion for receiving a cylindrical piston/sealing unit. The piston portion of the piston/sealing unit includes a compressible tip which is adapted to a butt up against the outer end of the ferrule body portion of the fiber optic termination or connector. A cylindrical end cap fits over the upper end of the body member for holding the fiber optic termination in place on the body member and causing a seal to be formed between the termination or connector and the upper portion of the body member adjacent the compressible tip of the plunger. The parts, when fitted together, are placed in a centrifuge which is operated for a predetermined spin cycle, so as to cause any bubbles in the uncured liquid adhesive to be vented outwardly from the termination through the end cap.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: September 11, 2001
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventor: John R. Kolasinski
  • Patent number: 6132353
    Abstract: Red cells are separated from plasma or serum of whole blood by arranging an evacuated tube sealed by a self-sealing stopper above and preferably coaxial with a tube containing a blood sample and sealed by a self-sealing stopper. A hollow double ended needle is held by a fixture and is disposed between and coaxial with the tubes and the tubes are placed in the fixture in a vertical position in a centrifuge and rotated about and spaced from an axis parallel to the axis of the tubes and needle. After the red cells are separated from the serum and/or plasma the tubes are pushed toward one another so that the needle penetrates both stoppers and the serum and/or plasma is drawn into the upper tube. The tubes and needle are separated while still being rotated so that the whole blood components are separated as required.
    Type: Grant
    Filed: July 21, 1997
    Date of Patent: October 17, 2000
    Inventors: James W. Winkelman, Oren Zinder, Manfred Grumberg, Jacob Schreibman
  • Patent number: 6001310
    Abstract: A pliable centrifuge tube array includes a number of tubes having collars which are interconnected by flexible tethers that permit the tubes to diverge when they are placed into holes in a centrifuge rotor. The tubes have a noncircular cross section providing grooves or apexes in which pellets of dense material preferentially collect. In some embodiments, the tethers or tubes have a latching mechanism such as mating projections and sockets which, when engaged, hold the tubes together in close array. The tubes may have individual lids which can be opened and closed simultaneously with a prying tool specially designed for the purpose.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: December 14, 1999
    Inventors: John V. Shaffer, Richard Braverman
  • Patent number: 5833908
    Abstract: In the compression molding of a fixed angle centrifuge rotor utilizing discontinuous fibers, sample tube apertures cores present in the net-shape mold are covered with pre-cured sample tube aperture inserts. The sample tube aperture inserts have a constant and unchanging inside diameter and are formed from composite fiber. This composite fiber extends from the closed bottom of the inserts, upwardly along the sides of the inserts to the open top of the inserts to provide tensile strength longitudinally of the sample tube aperture inserts. The sample tube aperture inserts have a regular and smooth inside for first accommodating the sample tube aperture cores when the rotor is compression molded and later the sample tubes themselves when the rotor is fully fabricated. These inserts have an irregular outside for forming an interference fit with the subsequently formed compression molded rotor body.
    Type: Grant
    Filed: November 21, 1995
    Date of Patent: November 10, 1998
    Assignee: Piramoon Technologies, Inc.
    Inventors: Alireza Piramoon, Robert Wedemeyer, Guillaume Crete
  • Patent number: 5527258
    Abstract: A feed accelerator system for use in a centrifuge, the system comprising a conveyor hub rotatably mounted substantially concentrically within a rotating bowl, and an accelerator including a cone-shaped inside surface disposed between an accelerator base and an accelerator small diameter section. The accelerator is secured proximately to its base within the conveyor hub so that the accelerator rotates with the conveyor hub. A distributor including a distributor surface having no sharp bends or junctions is secured to the small diameter section. A plurality of accelerator vanes are disposed on the cone-shaped inside surface and extend proximately from the small diameter section and terminate at a location on the cone-shaped inside surface proximate to the accelerator base so that an unvaned portion of the cone-shaped inside surface forms a smoothener section.
    Type: Grant
    Filed: September 16, 1994
    Date of Patent: June 18, 1996
    Assignee: Baker Hughes Incorporated
    Inventors: Woon F. Leung, Ascher H. Shapiro
  • Patent number: 5494579
    Abstract: A continuous decanter assembly suitable for processing nuclear materials comprises a mechanical assembly for driving a decanter bowl and an Archimedean screw. Sealing structure is provided to enable the decanter bowl and screw to be disconnected from the mechanical assembly and accessed by an operator without risk of nuclear contamination.
    Type: Grant
    Filed: May 26, 1994
    Date of Patent: February 27, 1996
    Assignee: Robatel
    Inventors: Michel Robatel, Alain Fraux, Jean-Pierre Davier
  • Patent number: 5477021
    Abstract: Spacers are roller welded or laser welded to a disk, welding the interstices between the spacers and the disk liquid tight. Nothing can accordingly accumulate in the interstices to contaminate the centrifugate.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: December 19, 1995
    Assignee: Westfalia Separator
    Inventors: Werner Kohlstette, Walter Tohermes, Alfons G. Beikel
  • Patent number: 5399144
    Abstract: A centrifuge tube adapter for supporting a closed tube in a cavity of a vertical angle centrifuge rotor includes an inboard and an outboard adapter segment. A hinge connects the segments and supports relative pivotal movement of one segment with respect to the other. The hinge comprises a pair of axles formed at the lower end of one segment and a pair of trunnions formed at a corresponding location on the other segment. The inboard segment has a flange and the outboard segment has a channel therein sized to receive the flange. The flange has serrations thereon.
    Type: Grant
    Filed: November 4, 1993
    Date of Patent: March 21, 1995
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: William A. Romanauskas, Edward T. Sheeran, Jr.
  • Patent number: 5382220
    Abstract: An adapter for a centrifuge tube comprises two segments that may be hinged along a hinge axis that extends perpendicular to the axis of the adapter.
    Type: Grant
    Filed: April 12, 1994
    Date of Patent: January 17, 1995
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: William A. Romanauskas, Edward T. Sheeran, Jr.
  • Patent number: 5308309
    Abstract: An improved apparatus for automatically retaining a removable chamber during operation, in a system for separating and irradiating multi-component fluids. A clamp arm that having two ends is provided: the first acts as a securing means, the second contains the clamp arm center of mass. The clamp arm is pivoted on the rotating chuck near the interface of the rotating chuck interior and the removable chamber exterior. The pivot allows for rotation of the clamp arm about the pivot, the pivot being located between the first end with the securing means and the second end containing the center of mass. When the chuck is rotating, the end of the clamp arm containing the center of mass rotates outward, causing the clamp arm securing means to pivot above the removable chamber thereby securing it in place.
    Type: Grant
    Filed: December 23, 1992
    Date of Patent: May 3, 1994
    Assignee: Therakos, Inc.
    Inventor: Livingston B. Morris
  • Patent number: 5236409
    Abstract: An adapter having a body and a cooperating cover with a seal therebetween is characterized by a stop surface provided on the exterior surface the body. The body and the cover are held together by a clamping bail that is either separate from or, more preferably, pivotally mounted to, the body. The bail is slidably movable over the body and the cover from an open to a clamping position. In the clamping position the bail abuts against the stop surface with the major axis of the bail being most preferably collinear with the major axis of the adapter. With the bail in the clamping position the cover is held to the body in a manner that compresses the seal therebetween. The bail is formed of a material having sufficient strength to withstand a vertical force created by the pressure of a liquid carried in the tube under centrifugation.
    Type: Grant
    Filed: October 31, 1991
    Date of Patent: August 17, 1993
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: William A. Romanauskas
  • Patent number: 5186709
    Abstract: In the cuvette rotor (20) having circularly arranged and radially extending individual cuvettes (10) which are closed on all sides, each of the cuvettes (10) has two chambers (1, 2) which are separated from one another by a barrier (11). Each chamber (1, 2) is provided with an orifice (3, 4) for filling. Vessels (9) which are closed on all sides are arranged between the individual cuvettes (10), the bottom part (15) of each vessel having a barrier (13) which divides the vessel into two chambers (5, 6), and the upper part (14) being provided with an orifice (22) in the area of the chamber (5) arranged close to the axis of rotation and with a guard (12), which protrudes into the peripherally arranged chamber (6), in the area of the peripherally arranged chamber (6).
    Type: Grant
    Filed: October 26, 1990
    Date of Patent: February 16, 1993
    Assignee: Behringwerke Aktiengesellschaft
    Inventor: Alfred R. Hissung
  • Patent number: 5156818
    Abstract: Hazardous radioactive waste is compacted and cast into safely handled monolithic castings having a radiation barrier wall completely enclosing the radioactive waste by centrifugal casting processes in which the barrier wall may be either a pre-formed shell transported to the jobsite or it may be formed by biaxial centrifugal casting and curing of the barrier wall in a mold. When a pre-formed shell is used, means are provided for thickening the radiation barrier if necessary by biaxial casting of additional barrier material inside of the shell. Castable radioactive material is cast inside the barrier wall before removal of the casting mold from the finished cast monolith. The cast monolith is supported for rotation as the mold is removed therefrom so that additional impact resisting and radiation barrier material can also easily be applied to the exterior surface monolith if radiation leakage exceeds tolerance levels.
    Type: Grant
    Filed: June 19, 1991
    Date of Patent: October 20, 1992
    Assignee: Alternative Technologies for Waste, Inc.
    Inventors: Frank Manchak, Jr., Frank Manchak, III
  • Patent number: 5067938
    Abstract: In a centrifugal separator which has in the top panel of its case an opening communicating with a rotor chamber and a control panel disposed behind the opening, a lid for covering the opening has a cutaway made in its lower portion for receiving the control panel and the pivot of the lid is extended laterally to the rear of the control panel. The lid is spring biased toward its open position and is opened by depression of a foot pedal that is connected to a lid lock mechanism. The control panel includes an indicator of rotor rotational frequency and rotor chamber temperature, the indicator being supplied with electrical signals produced by sensors within the case of the centrifugal separator.
    Type: Grant
    Filed: March 18, 1988
    Date of Patent: November 26, 1991
    Assignee: Kabushiki Kaisha Kubota Seisakusho
    Inventors: Tadahiro Uchida, Kuniyuki Shimamura, Hayabu Nogawa, Keikichi Saito, Minoru Hara
  • Patent number: 5062826
    Abstract: The invention provides a device for locking the base of a blood centrifugation cell on a rotatable generally disc shaped chuck plate. The chuck plate encloses a plurality of elastic locators which extend radially a slight distance from the periphery of the plate. The plate further encloses a plurality of locking means which are biased to remain within the dimensions of the plate at rest and which are radially extendable by centrifugal force to extend beyond the periphery of the plate. An annular locking ring engages the base of the cell and extends around the periphery of the chuck plate. The locking ring has a plurality of internal recesses for initially receiving the elastic locators, and the locking means during centrifugation to secure the cell to the chuck plate.
    Type: Grant
    Filed: July 6, 1990
    Date of Patent: November 5, 1991
    Inventors: Marco Mantovani, Giorgio Rossetto
  • Patent number: 5043103
    Abstract: A casting containing toxic waste is made by centrifugally casting toxic waste in a pre-formed cage having heat conducting means therein. The casting is formed with suitable shielding materials selected as a function of the waste being cast. The finished casting contains passageways through which heat is removed. These passageways are oriented such that when two or more castings are stacked in abutment, the passageways of adjacent castings interconnect.
    Type: Grant
    Filed: March 23, 1989
    Date of Patent: August 27, 1991
    Inventors: Frank Manchak, Jr., Frank E. Manchak, II, Michael E. Manchak, Peter J. Manchak
  • Patent number: 5024647
    Abstract: The invention is directed to a centrifugal contactor for solvent extraction systems. The centrifugal contactor is provided with an annular vertically oriented mixing chamber between the rotor housing and the rotor for mixing process liquids such as the aqueous and organic phases of the solvent extraction process used for nuclear fuel reprocessing. A set of stationary helically disposed vanes carried by the housing is in the lower region of the mixing chamber at a location below the process-liquid inlets for the purpose of urging the liquids in an upward direction toward the inlets and enhancing the mixing of the liquids and mass transfer between the liquids. The upper region of the mixing vessel above the inlets for the process liquids is also provided with a set helically disposed vanes carried by the housing for urging the process liquids in a downward direction when the liquid flow rates through the inlets are relatively high and the liquids contact the vane set in the upper region.
    Type: Grant
    Filed: June 13, 1989
    Date of Patent: June 18, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Robert T. Jubin, John D. Randolph
  • Patent number: 5024649
    Abstract: A centrifuge bowl head including a bowl head plate, a bowl spoke attached to an outer circumference of the bowl plate, and a bowl spoke plow attached to the bowl spoke, the bowl spoke plow impinging upon a wearing material at an angle less than seventy-five degrees.A bowl head further including a bowl head plow connected to the bowl head plate, the bowl spoke plow having an additional directing angle, the bowl spoke plow being of unitary construction and the bowl spokes defining discharge ports, the area of the bowl spokes forming a ratio with the area of the discharge ports to allow material under the bowl spokes to have an included angle of 120 degrees or less.
    Type: Grant
    Filed: August 30, 1988
    Date of Patent: June 18, 1991
    Assignee: Bird Machine Company
    Inventor: Clement V. Smith
  • Patent number: 5008045
    Abstract: A casting containing toxic waste is made by centrifugally casting toxic waste in a pre-formed cage having heat conducting means therein. The casting is formed with suitable shielding materials selected as a function of the waste being cast. The finished casting may contain passageways through which heat is removed. These passageways are oriented such that when two or more castings are stacked in abutment, the passageways of adjacent castings interconnect. Also disclosed is a method and apparatus for forming castings of polygonal exterior cross section having a contaminant barrier wall of substantially uniform thickness so that the waste storage volume of the castings is maximized and so that the castings may be stacked and stored in honeycomb fashion in a respository to minimize dead storage space.
    Type: Grant
    Filed: July 21, 1989
    Date of Patent: April 16, 1991
    Assignee: Alternative Technologies for Waste, Inc.
    Inventors: Frank Manchak, Jr., Frank E. Manchak, II, Michael E. Manchak, Peter J. Manchak
  • Patent number: 4997417
    Abstract: A seal system for mounting a centrifuge within an opening between an area which is sterile and a contiguous area wherein the rotating basket of the centrifuge and its enclosure are accessible within the sterile area and are hermetically sealed with respect to the contiguous area.
    Type: Grant
    Filed: January 18, 1990
    Date of Patent: March 5, 1991
    Assignee: Robatel
    Inventor: Michel Martin
  • Patent number: RE43547
    Abstract: A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: July 24, 2012
    Assignee: Harvest Technologies Corporation
    Inventors: James R. Ellsworth, Steven F. Levesque