Hetero Ring Containing Antidote Patents (Class 504/104)
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Patent number: 10000765Abstract: To identify a cytochrome P450 involved in the detoxification and metabolism of a specific growth inhibitor. Provided is a gene encoding a cytochrome P450 classified into Indica rice-derived CYP72A31, comprising a polynucleotide encoding a protein comprising an amino acid sequence of SEQ ID NO: 2.Type: GrantFiled: October 12, 2012Date of Patent: June 19, 2018Assignees: NATIONAL INSITUTE OF AGROBIOLOGICAL SCIENCE, KUMIAI CHEMICAL INDUSTRY CO., LTDInventors: Hiroaki Saika, Fumio Taguchi, Kiyosumi Hori, Takashi Matsumoto, Tsuyoshi Tanaka, Junko Horita, Koichiro Kaku, Tsutomu Shimizu
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Patent number: 9856201Abstract: The present disclosure relates, in general, to 5-halo-3,6-dichlorosalicylic acid compounds, 5-halo-3,6-dichlorosalicyaldehyde compounds, processes for preparing 5-halo-3,6-dichlorosalicylic acid compounds, processes for preparing 5-halo-3,6-dichlorosalicyaldehyde compounds, processes for preparing 3,6-dichlorosalicylic acid compounds, and processes that employ such compounds as intermediates in the preparation of the herbicide dicamba.Type: GrantFiled: June 3, 2015Date of Patent: January 2, 2018Assignee: Monsanto Technology LLCInventors: Terri L. Boehm, Mangesh Bore, Jeffery N. Carroll, G. Davis Harris, Jr., Matthew D. McReynolds, Justin R. Struble, Daniel P. Walker
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Patent number: 9682966Abstract: The invention provides novel ligands of Kappa (?) opioid receptors, such as can be used to modulate a Kappa opioid receptor. Methods of synthesis and methods of use are also provided. Compounds of the invention can be used therapeutically in the treatment of dissociative disorders or pain, or to provide neuroprotection, or to induce diuresis, or to modulate the immune system, or for treatment of one or more of an affective disorders comprising depression or stress/anxiety; an addictive disorder; alcoholism, epilepsy; a cognition deficiency; schizophrenia; Alzheimer's disease; or pain.Type: GrantFiled: August 16, 2013Date of Patent: June 20, 2017Assignee: The Scripps Research InstituteInventors: Edward Roberts, Miguel A. Guerrero, Mariangela Urbano, Hugh Rosen
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Patent number: 9232791Abstract: The invention relates to the use of one or more acylsulfonamide safener compounds of formula (I): for modifying plant development of useful plants. The use provides an increase in root growth and/or a regulation in shoot growth of the plants.Type: GrantFiled: December 9, 2008Date of Patent: January 12, 2016Assignee: Bayer Intellectual Property GmbHInventors: Christopher Hugh Rosinger, Frank Ziemer
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Patent number: 8901036Abstract: The invention relates to combinations of sulfonylurea herbicides (A) and their salts in which R2 is H, OH, aliphatic hydrocarbon radical or hydrocarbon-oxy radical, and R1 is an acyl radical, and the other symbols are as defined in claim 1, and safeners of type (B1) and (B2) in which the symbols are as defined in claim 1.Type: GrantFiled: March 1, 2006Date of Patent: December 2, 2014Assignee: Bayer Cropscience AGInventors: Lothar Willms, Hermann Bieringer, Erwin Hacker, Gerhard Schnabel, Klaus Lorenz
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Publication number: 20130012384Abstract: The present invention relates to novel compounds of the formula (I), in which W, X, Y, Z, G, A and t have the meanings given above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides. Moreover, the invention relates to selective herbicidal compositions comprising, firstly, the spiroheterocyclic tetronic acid derivates and, secondly, a crop plant compatibility-improving compound. The present invention furthermore relates to increasing the activity of crop protection compositions comprising in particular phenyl-substituted bicyclooctane-1,3-dione derivates by adding ammonium salts or phosphonium salts and, if appropriate, penetrants, to the corresponding compositions, to processes for their preparation and to their use in crop protection as insecticides and/or acaricides and/or for preventing unwanted plant growth.Type: ApplicationFiled: September 14, 2012Publication date: January 10, 2013Applicant: Bayer CropScience AGInventors: Thomas BRETSCHNEIDER, Reiner Fischer, Stefan Lehr, Olga Malsam, Arnd Voerste
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Patent number: 8268747Abstract: Clomazone safens rice from the slight amounts of damage caused by penoxsulam at concentrations required to adequately control undesirable vegetation.Type: GrantFiled: April 26, 2010Date of Patent: September 18, 2012Assignee: Dow AgroSciences, LLC.Inventors: Richard K. Mann, Deborah G. Shatley
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Publication number: 20120088667Abstract: A compound selected from a composition comprising an auxin, an auxin precursor, an auxin metabolite or a derivative of said auxin, auxin precursor or auxin metabolite and acetaminophen or a derivative thereof for use as a plant safener.Type: ApplicationFiled: April 7, 2010Publication date: April 12, 2012Applicant: TAMINCO, NAAMLOZE VENNOOTSCHAPInventors: Richard Williams, Peter Roose, Johan Josef De Saegher
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Publication number: 20110130284Abstract: The invention relates to novel compounds of the formula (I) in which W, X, Y, Z, A and G have the meanings given above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides, and also to selective herbicidal compositions comprising, firstly, the cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives of the formula (I) and, secondly, at least one crop plant compatibility-improving compound. The invention relates furthermore to increasing the activity of crop protection compositions comprising compounds of the formula (I) by adding ammonium or phosphonium salts and, if appropriate, penetrants.Type: ApplicationFiled: November 22, 2007Publication date: June 2, 2011Applicant: Bayer CropScience AGInventors: Reiner Fischer, Christian Arnold, Olga Malsam, Jan Dittgen, Dieter Feucht, Ulrich Görgens, Martin Jeffrey Hills, Christopher Hugh Rosinger
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Publication number: 20100113270Abstract: Cyclohexanedione compounds of Formula (I) wherein R1 is methyl, ethyl, n-propyl, iso-propyl, cyclopropyl, halomethyl, haloethyl, halogen, vinyl, ethynyl, methoxy, ethoxy, halomethoxy or haloethoxy, R2 and R3 are, independently hydrogen, halogen, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy, C1-C6haloalkoxy, C2-C6alkenyl, C2-C6haloalkenyl, C2-C6alkynyl, C3-C6alkenyloxy, C3-C6haloalkenyloxy, C3-C6alkynyloxy, C3-C6cycloalkyl, C1-C6alkylthio, C1-C6alkylsulfinyl, C1-C6alkylsulfonyl, C1-C6alkylsulfonyloxy, C1-C6haloalkylsulfonyloxy, cyano, nitro, phenyl, phenyl substituted by C1-C4alkyl, C1-C3Cahaloalkyl, C1-C3alkoxy, C1-C3haloalkoxy, cyano, nitro, halogen, C1-C3alkylthio, C1-C3alkylsulfinyl or C1-C3alkylsulfonyl, or heteroaryl or heteroaryl substituted by C1-C3Calkyl, d.Type: ApplicationFiled: March 7, 2008Publication date: May 6, 2010Applicant: SYNGENTA CROP PROTECTION, INC.Inventors: Christopher John Mathews, John Finney, Louisa Robinson, Melloney Tyte, Michel Muehlebach, Jean Wenger
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Publication number: 20100062939Abstract: The present invention relates to a herbicide/safener combination comprising components (A) and (B), where (A) denotes one or more compounds or salts thereof from the group described by the general formula (I): in which R1 is halogen, preferably fluorine or chlorine, R2 is hydrogen and R3 is hydroxyl or R2 and R3 together with the carbon atom to which they are attached are a carbonyl group C?O and R4 is hydrogen or methyl; and (B) is one or more compounds from the group of the safeners.Type: ApplicationFiled: August 11, 2009Publication date: March 11, 2010Applicant: BAYER CROPSCIENCE AGInventors: Erwin Hacker, Christopher Hugh Rosinger, Chieko Ueno, Georg Bonfig-Picard, Frank Ziemer, Shinichi Shirakura
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Publication number: 20070238615Abstract: Liquid formulations in crop protection and their use Formulations with delayed release of agrochemical actives from the group of fatty acid synthetase inhibitors are suitable for reducing phytotoxicity in crop plants when said agrochemical actives are used to check unwanted detrimental organisms in the crops.Type: ApplicationFiled: April 2, 2007Publication date: October 11, 2007Applicant: Bayer CropScience GmbHInventors: Hans-Peter Krause, Gerhard Schnabel, Roland Deckwer, Udo Bickers
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Publication number: 20070167328Abstract: A herbicide composition for paddy field characterized by containing (a) a herbicidal difluoromethanesulfonamide derivative represented by the formula (I) and (b) at least one herbicidal compound selected from the group consisting of pretilachlor, butachlor, alachlor, metolachlor, acetochlor, clomeprop, bromobutide, benfuresate, indanofan, pyrazolate, benzofenap, pyrazoxyfen, pyraclonil, oxaziclomefone, bensulfuron-methyl, azimsulfuron, imazosulfuron, pyrazosulfuron-ethyl, cyclosulfamuron, ethoxysulfuron, halosulfuron-methyl, orthosulfamuron, cinosulfuron, metsulfuron-methyl, penoxsulam, thiobencarb, pyributycarb, molinate, dimethametryn, simetryn, cafenstrole, quinclorac, anilofos, mefenacet, fentrazamide, pentoxazone, oxadiargyl, oxadiazon, benzobicyclon, mesotrione, AVH301 (code no.Type: ApplicationFiled: January 12, 2007Publication date: July 19, 2007Applicant: Bayer CropScience GmbHInventors: Keiji Endo, Shinichi Shirakura, Shin Nakamura, Natsuko Minegishi
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Patent number: 7141531Abstract: The invention relates to combinations of sulfonylurea herbicides (A) and their salts in which R2 is H, OH, aliphatic hydrocarbon radical or hydrocarbon-oxy radical, and R1 is an acyl radical, and the other symbols are as defined in claim 1, and safeners of type (B1) and (B2) in which the symbols are as defined in claim 1.Type: GrantFiled: June 19, 2003Date of Patent: November 28, 2006Assignee: Hoechst Schering AgrEvo GmbHInventors: Lothar Willms, Hermann Bieringer, Erwin Hacker, Gerhard Schnabel, Klaus Lorenz
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Patent number: 6890885Abstract: A herbicidal composition that, in addition to comprising customary inert formulation adjuvants, comprises a) a compound of formula I ?wherein the substituents are as defined in claim 1, and b) a synergistically effective amount of one or more compounds of formulae 2.1 to 2.51. The compositions according to the invention may also comprise a safener.Type: GrantFiled: July 23, 2002Date of Patent: May 10, 2005Assignee: Syngenta Corp Protection, Inc.Inventor: Willy T. Rüegg
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Patent number: 6855667Abstract: The present invention relates to protection of plants from unintended phytotoxic injury due to application of a herbicide to reduce competition for the plant of interest. A preferred herbicide used in the context of the present invention is clomazone. The unintended phytotoxic injury is avoided by application of a safening-effective amount of one or more of the compounds described by formula (I) wherein T and T1 are independently selected from the group of hydrogen, alkyl, haloalkyl, alkoxyalkyl, alkenyl, and alkynyl; U is oxygen or sulfur, and; V, W, X, Y, and Z are independently selected from the group of hydrogen, halogen, alkyl, haloalkyl, and alkoxy. The present invention is preferably used for growing corn, wheat, and cotton in the presence of the otherwise phytoxic effects of clomazone, for example.Type: GrantFiled: January 5, 2001Date of Patent: February 15, 2005Assignee: FMC CorporationInventor: David W. Keifer
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Patent number: 6544927Abstract: The invention provides methods and compositions for reducing defoliation of plants and trees. Preferably, the methods and compositions of the invention reduce defoliation associated with the application of abscission agents or herbicides to plants and trees.Type: GrantFiled: June 29, 2001Date of Patent: April 8, 2003Assignee: University of FloridaInventor: Jacqueline Kay Burns
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Publication number: 20020183205Abstract: The invention provides methods and compositions for reducing defoliation of plants and trees. Preferably, the methods and compositions of the invention reduce defoliation associated with the application of abscission agents or herbicides to plants and trees.Type: ApplicationFiled: June 29, 2001Publication date: December 5, 2002Inventor: Jacqueline Kay Burns
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Publication number: 20020055435Abstract: The invention relates to a herbicidal composition comprising a herbicidally acceptable carrier and/or surface active agent and, as active ingredient, a synergistically effective amount ofType: ApplicationFiled: August 24, 2001Publication date: May 9, 2002Applicant: Intellectual Property DepartmentInventors: Helmut Siegfried Baltruschat, Astrid Brandt
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Patent number: 6197876Abstract: The present invention teaches heterocyclic amine modified siloxanes and their use, a preferred of which is as adjuvants for pesticides. The heterocyclic amine modified siloxanes have siloxane backbones with pendant, terminal or intermediate heterocyclic amine groups, which may contain one or more heteroatoms, i.e., nitrogen, sulfur or oxygen. The heterocyclic amine groups or the siloxane may be functionalized further with alkyl or alkyleneoxide groups.Type: GrantFiled: February 24, 1999Date of Patent: March 6, 2001Assignee: CK Witco CorporationInventors: George A. Policello, Gerald J. Murphy
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Patent number: 5880066Abstract: The disclosure herein relates to the use of a variety of antidotal compounds to safen crop plants from the phytotoxicity of azolopyrimidine sulfonamide herbicides.Type: GrantFiled: December 6, 1991Date of Patent: March 9, 1999Assignee: Monsanto CompanyInventors: Barbara Heard Wells, Harrison Ross Hakes, David James Mayonado, John Paul Chupp
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Patent number: 5739079Abstract: Substituted (hetero)aryl compounds, process for their preparation, agents containing them, and their use as safenersCompounds of the formula I and their salts, as defined in claim 1, are suitable as safeners for protecting crop plants against the phytotoxic side-effects of herbicides.Type: GrantFiled: May 15, 1995Date of Patent: April 14, 1998Assignee: Hoechst AktiengesellschaftInventors: Xenia Holdgrun, Lothar Willms, Klaus Bauer, Klaus Trinks, Hermann Bieringer
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Patent number: 5710100Abstract: The disclosure herein relates to the use of certain amides of dichloroacetic acid and other compounds as safener/antidotal compounds to reduce the phytotoxicity to crop plants, especially corn, of imidazolinone-type herbicides alone or in admixture with other co-herbicidal compounds, e.g., .alpha.-haloacetamides.Type: GrantFiled: December 29, 1994Date of Patent: January 20, 1998Assignee: Monsanto CompanyInventors: Brett Hayden Bussler, Ronald Joseph Brinker
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Patent number: 5696050Abstract: There is provided a method for safening herbicides in crop plants by using substituted benzopyran or tetrahydronaphthalene compounds of formula I ##STR1## Further provided are compounds of formula II and compositions comprising a herbicide and an antidotally effective amount of a substituted benzopyran or tetrahydronaphthalene compound of formula I.Type: GrantFiled: June 6, 1995Date of Patent: December 9, 1997Assignee: American Cyanamid CompanyInventors: Gail Ezra Cary, Nina Rose Quinn
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Patent number: 5565408Abstract: Cyanoquinoline compounds Ia or Ib ##STR1## where R.sup.1 is CH.dbd.C(CN).sub.2 ; CH.dbd.N--N.dbd.CH--(5-quinolyl); methylsulfonyl; CH.dbd.NOH; halogen; hydroxyl; nitro; cyano; unsubstituted or substituted C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or C.sub.1 -C.sub.4 -alkylthio, pyrrolidinyl; piperidinyl; morpholinyl; thiomorpholinyl; unsubstituted or substituted phenyl, phenoxy, phenylthio, phenyldithiolyl, phenylsulfonyl or pyrrolyl;m is 0, 1, 2 or 3;R.sup.2 is hydrogen; hydroxyl; halogen; C.sub.1 -C.sub.4 -alkoxy; --NR.sup.3 R.sup.4 ; --NR.sup.5 --CXR.sup.6 or --N.dbd.CR.sup.7 R.sup.8 ;R.sup.3 is hydrogen or unsubstituted or substituted C.sub.1 -C.sub.4 -alkyl;R.sup.4 is a radical R.sup.3 ; C.sub.1 -C.sub.4 -alkylamino; di-C.sub.1 -C.sub.4 -alkylamino; substituted C.sub.1 -C.sub.4 -alkyl; CH.dbd.N--(3-cyano-2-quinolinyl); or R.sup.3 and R.sup.4 together form C.sub.4 - or C.sub.3 -alkylene which may be interrupted by a hetero atom, or unsubstituted or substituted 1,3-butadienyl;R.sup.5 and R.sup.Type: GrantFiled: April 17, 1995Date of Patent: October 15, 1996Assignee: BASF AktiengesellschaftInventors: Helmut Hagen, Juergen Pfister, Gunter Brill, Gerhard Nilz, Bruno Wuerzer, Karl-Otto Westphalen
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Patent number: 5491123Abstract: Herbicides contain one or more antagonistic 3-aminobenzo[b]thiophenes I ##STR1## wherein the variables on the compound of formula I are defined in the specification.A) the group consisting of the cyclohexenone derivatives orB) the group consisting of the 4-hetaryloxyphenoxyacetic acid derivatives.Type: GrantFiled: February 4, 1994Date of Patent: February 13, 1996Assignee: BASF AktiengesellschaftInventors: Helmut Hagen, Gerhard Nilz, Thomas Roetsch, Helmut Walter, Andreas Landes
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Patent number: 5488027Abstract: The invention relates to herbicidal compositions which contain an effective amount ofA) one or more herbicides selected from the group comprising sulfonylureas and imidazolinones andB) one or more safeners selected from the group comprisingB1) phenyl-substituted imidazole-, imidazoline- and triazolecarboxylic acid derivatives and the benzyloxazolinecarboxylic acid derivatives and/orB2) quinolin-8-oxyalkanecarboxylic acid derivatives,with the exception of combinations of imidazolinones with compounds of the formula B2.The compositions are particularly suitable for protecting plants against phytotoxic secondary effects of sulfonylurea herbicides and imidazolinone herbicides. In the case of the imidazolinone herbicides, the invention also relates to a method of protecting corn plants, by applying post-emergence an effective amount of a quinolin-8-oxyalkanecarboxylic acid derivative together with the imidazolinone herbicide to the plants or the area under cultivation.Type: GrantFiled: December 19, 1991Date of Patent: January 30, 1996Assignee: Hoechst AktiengesellschaftInventors: Klaus Bauer, Hermann Bieringer
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Patent number: 5484760Abstract: The disclosure herein relates to means for combatting the adverse phytotoxic action to crops arising from the interaction of various herbicidal compounds and biocidal compounds, e.g., insecticidal and/or fungicidal compounds. The means employed to reduce said interaction involves the safening action of various antidotal compounds.Type: GrantFiled: December 20, 1991Date of Patent: January 16, 1996Assignee: Monsanto CompanyInventors: Brett H. Bussler, Harrison R. Hakes, David J. Mayonado
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Patent number: 5441922Abstract: Herbicide/safener combinations ofA) herbicides selected from the group of the 2-acylated 1,3-dicarbonyl compounds or salts thereof, andB) safeners B1 and/or B2 ##STR1## as they are defined in claim 1, are suitable for controlling harmful plants in crops such as cereals, maize and rice.Type: GrantFiled: December 29, 1992Date of Patent: August 15, 1995Assignee: Hoechst AktiengesellschaftInventors: Oswald Ort, Lothar Willms, Hans-Joachim Zeiss, Stephan Mller, Herbert Stark, Rainer Schutze, Klaus Bauer, Hermann Bieringer
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Patent number: 5428000Abstract: An antagonism caused by the use of a herbicide for narrowleaf weeds together with a herbicide for broadleaf weeds is inhibited by using together with hydrophilic polymeric compound containing a quaternary ammonium salt and having 10,000 to 1,000,000 of molcular weight.Type: GrantFiled: March 23, 1994Date of Patent: June 27, 1995Assignee: Toho Chemical Industry Co., Ltd.Inventors: Haruki Innami, Teruyuki Misumi, Makoto Konnai
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Patent number: 5422335Abstract: A herbicidal composition containing one or more substituted 2-aminothiophenes of the formula I ##STR1## where R.sup.1 and R.sup.2 together from a C.sub.4 -alkylene chain to which a benzene ring may be fused,R.sup.3 is --CN or CX--R.sup.6, where R.sup.6 is hydroxyl, C.sub.1 -C.sub.4 -alkoxy or amino,R.sup.4 is hydrogen or a phenyl group which may carry one or two nitro radicals,--PO(OR.sup.8).sub.2, --CX--R.sup.9, --SO.sub.2 R.sup.10, --CX--N(H) --CO--R.sup.8 or --CX--N(R.sup.7)--SO.sub.2 --R.sup.11,whereR.sup.8 is hydrogen, C.sub.1 -C.sub.4 -alkyl or phenyl groupR.sup.9 is C.sub.1 -C.sub.20 -alkyl, partially or completely halogenated C.sub.1 -C.sub.6 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.6 -cycloalkyl, or amino, C.sub.1 -C.sub.4 -alkylamino, C.sub.3 -C.sub.8 -cycloalkylamino, phenyl or phenylamino, where the aromatic moiety may carry at least one of nitro and halogen;R.sup.10 is C.sub.1 -C.sub.4 -alkyl or phenyl, which may carry one C.sub.1 -C.sub.4 -alkyl radical;R.sup.Type: GrantFiled: June 7, 1993Date of Patent: June 6, 1995Assignee: BASF AktiengesellschaftInventors: Helmut Hagen, Gerhard Nilz, Helmut Walter, Andreas Landes
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Patent number: 5407897Abstract: There is provided a method for safening herbicides in crop plants by using substituted benzopyran or tetrahydronaphthalene compounds of formula I ##STR1## Further provided are compounds of formula II and compositions comprising a herbicide and an antidotally effective amount of a substituted benzopyran or tetrahydronaphthalene compound of formula I.Type: GrantFiled: March 3, 1993Date of Patent: April 18, 1995Assignee: American Cyanamid CompanyInventors: Gail E. Cary, Nina R. Quinn
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Patent number: 5378677Abstract: Herbicidal agents containing at least one thiochromenone of the formula I ##STR1## where n is 1, 2, 3 or 4, and the radicals R.sup.3 may have different meanings when n is>1;R.sup.1 is hydrogen; cyano; halogen; substituted or unsubstituted alkyl, aryl or hetaryl;a group --XR.sup.4 or a group --COYR.sup.4, whereX is oxygen, sulfur and NR.sup.5,Y is oxygen and NR.sup.5,R.sup.4 is one of the following groups:hydrogen; formyl; alkyl; cycloalkyl; alkylcarbonyl; cycloalkylcarbonyl; alkylsulfonyl; cycloalkylsulfonyl;substituted or unsubstituted aryl, hetaryl, arylcarbonyl, hetarylcarbonyl, arylsulfonyl or hetarylsulfonyl;andR.sup.5 is hydrogen or substituted or unsubstituted alkyl, aryl or hetaryl;R.sup.2 is hydrogen; cyano; nitroso; nitro; halogen; substituted or unsubstituted alkyl, alkoxy, alkylthio, aryl or hetaryl;a group --NR.sup.4 R.sup.5 or a group --COYR.sup.4, whereY, R.sup.4 and R.sup.5 have the above meanings;R.sup.Type: GrantFiled: January 19, 1993Date of Patent: January 3, 1995Assignee: BASF AktiengesellschaftInventors: Helmut Hagen, Peter Raatz, Helmut Walter, Andreas Landes
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Herbicidal compositions safened by 5-heterocyclic-substituted oxazolidine dihaloacetamides compounds
Patent number: 5256626Abstract: The disclosure herein relates to a new family of haloalkyl oxazolidinyl derivatives as antidotal compounds to reduce injury to crop plants by a variety of herbicides. The antidotal compounds are characterized particularly by having heterocyclyl or spiroheterocyclyl radicals attached to the 5-position of haloalkyl oxazolidine compounds and are especially useful as in-can antidotes against injury by acetanilide and thiocarbamate herbicides to corn, sorghum, soybeans, wheat, rice and other crops.Type: GrantFiled: July 3, 1991Date of Patent: October 26, 1993Assignee: Monsanto CompanyInventors: Eric L. Williams, Steven M. Massey, Brett H. Bussler, Ronald J. Brinker -
Patent number: 5215570Abstract: The N-acylsulfamoylphenylureas of formula I below are suitable as counter-agents (antidotes or safeners) for protecting cultivated plants from the phytotoxic action of herbicides. Suitable crops are preferably cereals, soybeans, sorghum, maize and rice, and suitable herbicides are sulfonylureas, chloroacetanilides and aryloxyphenoxypropionic acid derivatives.The N-acylsulfamoylphenylureas have the formula I ##STR1## wherein A is a radical selected from the group ##STR2## R.sub.1 is C.sub.1 -C.sub.4 -alkoxy or each of R.sub.1 and R.sub.2, independently of the other, is hydrogen, C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.sub.6 alkenyl, C.sub.3 -C.sub.6 alkynyl, ##STR3## or C.sub.1 -C.sub.4 alkyl substituted by C.sub.1 -C.sub.4 alkoxy or by ##STR4## or R.sub.1 and R.sub.2 together form a C.sub.4 -C.sub.6 alkylene bridge, or a C.sub.4 -C.sub.6 alkylene bridge interrupted by oxygen, sulfur, SO, SO.sub.2, NH or by --N(C.sub.1 -C.sub.4 alkyl)-, R.sub.3 is hydrogen or C.sub.1 -C.sub.4 alkyl, R.Type: GrantFiled: January 3, 1991Date of Patent: June 1, 1993Assignee: Ciba-Geigy CorporationInventors: Urs Burckhardt, Raafat Soliman, Werner Topfl, Hans-Rudolf Waespe
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Patent number: 5201933Abstract: The disclosure herein relates to the use of certain amides of dichloroacetic acid and other compounds as safener/antidotal compounds to reduce the phytotoxicity to crop plants, especially corn, of benzoic acid-type herbicides alone or in admixture with other co-herbicidal compounds, e.g., .alpha.-haloacetamides.Type: GrantFiled: October 12, 1990Date of Patent: April 13, 1993Assignee: Monsanto CompanyInventors: Knudt J. Miller, Brett H. Bussler
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Patent number: 5087640Abstract: Compounds of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are independently fluorine, chlorine or bromine atom, and R.sup.3 is a C.sub.4 -C.sub.7 alkyl having at least a branch at the C.sub.1 position, exhibit K.sup.+ channel opening activity and are useful as hypotensive agents and coronary vasodilators.Type: GrantFiled: June 27, 1990Date of Patent: February 11, 1992Assignee: Kanebo, Ltd.Inventors: Tominori Morita, Kazuya Yoshiizumi, Noriyasu Nishimura, Katsumi Goto, Takayuki Sukamoto, Kohichiro Yoshino