Hetero Ring Is Six-membered Including Nitrogen Patents (Class 504/177)
-
Patent number: 10934270Abstract: Disclosed are new small molecules having a substituted quinazoline core structure and the uses thereof for modulating glucocerebrosidase activity. Also disclosed are pharmaceutical compositions comprising the small molecules or activated glucocerebrosidase conjugated to the small molecules, which compositions may be administered in methods of treating diseases or disorders associated with glucocerebrosidase activity, including neurological diseases and disorders such as Gaucher's disease and Parkinson's disease.Type: GrantFiled: November 7, 2019Date of Patent: March 2, 2021Assignee: Northwestern UniversityInventors: Dimitri Krainc, Richard B. Silverman, Jianbin Zheng
-
Patent number: 10501423Abstract: The present disclosure relates to substituted phenyl sulfonyl phenyl triazole thiones, pharmaceutical compositions containing them, and methods of using them.Type: GrantFiled: March 27, 2019Date of Patent: December 10, 2019Assignee: Neuropore Therapies, Inc.Inventors: Wolfgang J. Wrasidlo, Emily M. Stocking, Srinivasa Reddy Natala, Diana Luz Price
-
Patent number: 10477865Abstract: Antifungal compounds, an antifungal compound extracted from Epicoccum purpurascens, also known as Epicoccum nigrum, methods of producing the antifungal compounds, isolates and compositions comprising the antifungal compounds, and methods of using the antifungal compounds.Type: GrantFiled: January 4, 2016Date of Patent: November 19, 2019Assignee: Auckland UniServices LimitedInventor: Silas Granato Villas-Boas
-
Patent number: 10450279Abstract: 1. The present invention relates to compounds of the formula I wherein the variables are defined in the description and claims, their preparation and uses thereof.Type: GrantFiled: June 5, 2015Date of Patent: October 22, 2019Assignee: BASF SEInventors: Wassilios Grammenos, Nadege Boudet, Bernd Mueller, Maria Angelica Quintero Palomar, Ana Escribano Cuesta, Erica May Cambeis, Jan Klaas Lohmann, Thomas Grote, Manuel Kretschmer, Ian Robert Craig, Marcus Fehr
-
Patent number: 9091918Abstract: A sulfonium salt having formula (1a) is provided wherein R1 is H, F, CH3 or CF3, R1a to R1m are each independently H or a monovalent hydrocarbon group, L is a single bond or divalent hydrocarbon group, X is a divalent alkylene group optionally substituted with fluorine, and n is 0 or 1. The sulfonium salt having a polymerizable anion provides for efficient scission of acid labile groups in a chemically amplified resist composition, and it is a very useful monomer from which a base resin for resist use is prepared.Type: GrantFiled: February 4, 2014Date of Patent: July 28, 2015Assignee: SHIN-ETSU CHEMICAL CO., LTD.Inventors: Masahiro Fukushima, Jun Hatakeyama, Masaki Ohashi, Teppei Adachi
-
Patent number: 8916502Abstract: An agent for improving lawn grass quality, which is excellent in promoting dwarfing of lawn grass, making the stem sturdy, increasing the leaf count, and improving greenness, is provided. An agent for improving lawn grass quality containing, as active ingredients, 5-aminolevulinic acid represented by formula (1): R2R1NCH2COCH2CH2COR3??(1) wherein R1 and R2 each independently represent a hydrogen atom, an alkyl group, an acyl group, an alkoxycarbonyl group, an aryl group or an aralkyl group; and R3 represents a hydroxyl group, an alkoxy group, an acyloxy group, an alkoxycarbonyloxy group, an aryloxy group, an aralkyloxy group or an amino group, or a derivative thereof or a salt of the acid or the derivative, and a gibberellin biosynthesis inhibitor.Type: GrantFiled: March 26, 2009Date of Patent: December 23, 2014Assignee: Cosmo Oil Co., Ltd.Inventors: Yasutomo Takeuchi, Shigeyuki Funada
-
Publication number: 20140075604Abstract: Method for per to provide a turf for sports, ornamental or recreational use, comprising the steps of: selecting a stoloniferous and/or rhizomatous plant species; cultivating a plurality of mother plants belonging to said stoloniferous and/or rhizomatous species up to reach a predetermined vegetative development, said mother plants comprising stolons and/or rhizomes having a plurality of nodes, wherein two successive nodes are connected by plant portions, or internodes; preparing at least one cutting from each mother plant of said plurality of mother plants, said cutting comprising at least one node and an internode, wherein said internode has a length set between 1 mm and 10 mm; and carrying out a vegetative propagation of a plurality of said cuttings in a desired site then obtaining said turf.Type: ApplicationFiled: April 7, 2011Publication date: March 13, 2014Inventors: Marco Volterrani, Maurizio Pacini
-
Publication number: 20140031230Abstract: An object of the present invention is to provide an auxin biosynthesis inhibitor superior to L-AOPP. The object can be attained by a compound represented by general formula (I): wherein, R1 to R5 and X are the same as defined in the specification or a salt or solvate thereof.Type: ApplicationFiled: February 28, 2012Publication date: January 30, 2014Inventors: Yukihisa Shimada, Ko Kikuzato, Megumi Narukawa, Tadao Asami, Kazuo Soeno
-
Patent number: 6008159Abstract: Method for controlling the proliferation of annual grass weeds in an area by applying to the area a composition of one or more species of Pyrenophora fungi or anamorphs thereof, or a toxin or toxin-containing preparation derived from one or more species of Pyrenophora fungi or anamorphs thereof in association with an agriculturally acceptable carrier.Type: GrantFiled: June 17, 1997Date of Patent: December 28, 1999Assignee: Minister of Agriculture for the State of New South WalesInventors: Richard William Medd, Mathew Alexander Campbell
-
Patent number: 5935906Abstract: Provided are compositions and methods of improving a plant growth factor. The compositions and methods contain combinations of aminoethoxyvinylglycine and mepiquat chloride. The compositions provide an improvement in a plant growth factor, such as an increase in yield in cotton plant.Type: GrantFiled: December 20, 1996Date of Patent: August 10, 1999Assignee: BASF CorporationInventors: Mary Callan, Warren E. Shafer, Candace L. Black-Schafer
-
Patent number: 5856273Abstract: A compound of formula (I): ##STR1## where E is oxygen or sulphur; A is CR.sup.3 or N where R.sup.3 is hydrogen or hydrocarbyl; D completes a 5 or 6-membered non-aromatic heterocyclic ring which optionally contains additional heteroatoms selected from oxygen, nitrogen or sulphur and which is optionally substituted by an optionally substituted lower hydrocarbyl group, or an optionally substituted heteroaryl group; R.sup.1 and R.sup.2 are each independently hydrogen; optionally substituted lower hydrocarbyl, or optionally substituted heteroaryl, or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached, form a heterocyclic ring; Z represents halogen optionally substituted lower hydrocarbyl, optionally substituted lower hydocarbyloxy, optionally substituted lower hydrocarbylthio, hydrocarbylsulphinyl or hydrocarbylsulphonyl, cyano, nitro, CHO, NHOH, ONR.sup.7' R.sup.7", SF.sub.5 ; CO (optionally substituted lower hydrocarbyl), acylamino, COOR.sup.7, SO.sub.2 NR.sup.8 R.sup.9, CONR.sup.Type: GrantFiled: October 6, 1995Date of Patent: January 5, 1999Assignee: Zeneca LimitedInventors: Ian Trevor Kay, John Edward Duncan Barton, David John Collins, Bogdan Kowalczyk, Glynn Mitchell, John Martin Shribbs, John Micheal Cox, Nigel John Barnes, Stephen Christopher Smith
-
Patent number: 5773388Abstract: Novel pyrimidine derivatives of the formula (I): ##STR1## wherein R1 is a C.sub.1 -C.sub.6 haloalkyl group, a C.sub.1 -C.sub.6 alkyl group, a C.sub.3 -C.sub.6 cycloalkyl group or the like, R2 is a hydrogen atom, a C.sub.1 -C.sub.6 alkyl group, a C.sub.3 -C.sub.6 cycloalkyl group or the like, and X is a carbonyl group or --C(R3)OH (wherein R3 is a hydrogen atom, a C.sub.1 -C.sub.6 alkyl group or the like).Type: GrantFiled: February 9, 1996Date of Patent: June 30, 1998Assignee: Nissan Chemical Industries, Ltd.Inventors: Jun Satow, Yasuo Kondo, Yoshihiro Kudo, Takumi Mikashima, Tsutomu Nawamaki, Yoichi Ito, Kazuhisa Sudo, Kunimitsu Nakahira, Shigeomi Watanabe, Kimihiro Ishikawa
-
Patent number: 5654255Abstract: Plant growth regulator (PGR) compositions include a plant growth regulating effective mixture of (A) a N,N-dimethyl piperidinium salt (preferably, mepiquat chloride), (B) a hexitol (preferably, myo-inositol), and optionally (C) a compound which promotes cytokinesis in plant cells (i.e., a cytokinin). The hexitol and cytokinin are most preferably provided collectively in the composition by the presence of an effective amount of coconut milk. Synergistic results in terms of enhanced cotton lint yields are obtained by applying the PGR compositions of this invention to growing cotton plants.Type: GrantFiled: May 14, 1996Date of Patent: August 5, 1997Assignee: BASF CorporationInventors: Thomas D. O'Neal, David E. Millhouse, Wilhelm Rademacher
-
Patent number: 5627134Abstract: Plant growth regulator (PGR) compositions include a plant growth regulating effective mixture of (A) a N,N-dimethyl piperidinium salt (preferably, mepiquat chloride), (B) a hexitol (preferably, myo-inositol), and optionally (C) a compound which. promotes cytokinesis in plant cells (i.e., a cytokinin). The hexitol and cytokinin are most preferably provided collectively in the composition by the presence of an effective amount of coconut milk. Synergistic results in terms of enhanced cotton lint yields are obtained by applying the PGR compositions of this invention to growing cotton plants.Type: GrantFiled: June 5, 1995Date of Patent: May 6, 1997Assignee: BASF CorporationInventors: Thomas D. O'Neal, David E. Millhouse, Wilhelm Rademacher
-
Patent number: 5525576Abstract: The efficacy of plant growth regulating agents and systemic insecticides for plants are enhanced by applying the agent in combination with a product from the oxidation of a hull-free, pentose-containing extract from seed hulls.Type: GrantFiled: October 3, 1994Date of Patent: June 11, 1996Inventors: Luis R. Medina-Vega, Joseph A. Hickey, Lewis E. Dillon
-
Patent number: 5500404Abstract: The object of the present invention is to provide a method of lily bulb dwarfing treatment which can be performed before planting, be practiced easily and permit to obtain a uniform dwarfing effect without any special experience and to provide thus dwarfing treated lily bulbs.Namely, according to the present invention, lily bulbs are submitted to the sprouting treatment, then thus sprouted lily bulbs are soaked in a dwarfing agent.Type: GrantFiled: January 27, 1994Date of Patent: March 19, 1996Assignee: Japan Tobacco Inc.Inventors: Junko Daimon, Yasuo Takeda
-
Patent number: 5198014Abstract: This application discloses hebricidal B-pyrazolylacrylic acids, compositions containing them, methods of preparing them, and methods for controlling undesired plant growth by preemergent or postemergent application of the herbicidal compositions to the locus where control is desired. The herbicidal compounds have the formula ##STR1## in which the radicals are defined in the claims.Type: GrantFiled: November 20, 1991Date of Patent: March 30, 1993Assignee: FMC CorporationInventor: Lester L. Maravetz
-
Patent number: 5190574Abstract: A herbicidal compound of formula (I): ##STR1## in which the dotted line indicates the presence of two double bonds arranged so as to form a fused hetero-aromatic ring system;Py is an optionally substituted pyrazole ring;W is O or NR.sup.1 ; where R.sup.1 is hydrogen or lower alkyl;X is (CH.sub.2).sub.n, CH.dbd.CH, CH(OR.sup.5)CH.sub.2, COCH.sub.2 ;where n is 0, 1 or 2;R.sup.2 and R.sup.3 are independently selected from H, optionally substituted alkyl, alkenyl or alkynyl, halogen, NR.sup.6 R.sup.7, or R.sup.2 and R.sup.3 together with the carbon to which they are attached form an optionally substituted alkenyl or cycloalkyl group;R.sup.4 is CO.sub.2 R.sup.8, CN, COR.sup.8, CH.sub.2 OR.sup.8, CH(OH)R.sup.8, CH(OR.sup.8)R.sup.9, CSNH.sub.2, COSR.sup.8, CSOR.sup.8, CONHSO.sub.2 R.sup.8, CONR.sup.10 R.sup.11, CONHNR.sup.10 R.sup.11, CONHN.sup.+ R.sup.10 R.sup.11 R.sup.12 R.sup.14-, CO.sub.2.sup.- R.sup.15+ or COON.dbd.CR.sup.10 R.sup.11 ;R.sup.15+ is an agriculturally acceptable cation and R.sup.Type: GrantFiled: February 7, 1991Date of Patent: March 2, 1993Assignee: Imperial Chemical Industries plcInventors: David P. J. Pearson, John E. D. Barton, Christopher J. Mathews, David Cartwright, Susan P. Barnett
-
Patent number: 5180418Abstract: Cycloalkanecarboxylic acid derivatives of formula I ##STR1## wherein W is ##STR2## and A is CO--R.sub.3 or CN; R.sub.1 is hydrogen or fluorine; R.sub.2 is halogen or cyano; R.sub.3 is chlorine, X--R.sub.5, amino, C.sub.1 -C.sub.4 alkylamino, d-C.sub.1 -C.sub.4 alkylamino, C.sub.2 -C.sub.4 haloalkylamino, di-C.sub.2 -C.sub.4 haloalkylamino, C.sub.1 -C.sub.4 hydroxyalkylamino, di-C.sub.1 -C.sub.4 hydroxyalkylamino, C.sub.3 -C.sub.4 alkenylamino, diallylamino, --N-pyrrolidino, --N-piperidino, --N-morpholino, --N-thiomorpholino, --N-piperidazino, the group --O--N.dbd.C--(R.sub.9)R.sub.10 or the group --N--R.sub.6 (OR.sub.6); each of R.sub.4 and R.sub.14, independently of the other, is hydrogen, fluorine, chlorine, bromine, C.sub.1 -C.sub.4 alkyl or trifluoromethyl; R.sub.5 is hydrogen, C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.4 alkoxy-C.sub.1 -C.sub.4 alkyl, halo-C.sub.1 -C.sub.8 alkyl, C.sub.1 -C.sub.10 alkylthio-C.sub.1 -C.sub.4 alkyl, di-C.sub.1 -C.sub.4 alkylamino-C.sub.1 -C.sub.4 alkyl, cyano-C.sub.1 -C.sub.Type: GrantFiled: July 19, 1991Date of Patent: January 19, 1993Assignee: Ciba-Geigy CorporationInventors: Georg Pissiotas, Hans Moser, Hans-Georg Brunner, Eginhard Steiner