Plural Ring Nitrogens In The Hetero Ring Patents (Class 504/197)
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Patent number: 11058090Abstract: Provided herein are hybrid True Potato Seeds (TPS). Also provided herein are potato plants grown from the present hybrid True Potato Seeds and the potato tubers produced by these plants. Also provided herein is use of the present potato tubers for vegetative propagation thereof and to the use of the present potato tubers as seed potato for producing potato tubers for consumption and the food processing industry. Specifically, provided herein are hybrid True Potato Seed (TPS), wherein the seed is tetraploid and is produced as an F1 of a cross between a tetraploid male potato line and a tetraploid female potato line and preferably to hybrid True Potato Seed (TPS) wherein said tetraploid male potato line and said tetraploid female potato line have a sufficient degree of genetic and phenotypic uniformity to yield, as F1, hybrid True Potato Seed (TPS).Type: GrantFiled: July 25, 2016Date of Patent: July 13, 2021Assignee: Bejo Zaden B.V.Inventors: Martinus Jacobus Theodorus Klaver, Albertus Johannes Maria Schrijver
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Patent number: 10336769Abstract: GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.Type: GrantFiled: February 28, 2017Date of Patent: July 2, 2019Assignee: Neurocrine Biosciences, Inc.Inventors: Graham Beaton, Mi Chen, Timothy Richard Coon, Todd Ewing, Wanlong Jiang, Willy Moree, Martin Rowbottom, Warren Wade, Liren Zhao, Richard Lowe, Nicole Smith, Neil Ashweek, Yun-Fei Zhu
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Patent number: 9567318Abstract: The present subject matter relates to a compound represented by the general formula (I) or (I?) or a pharmacologically acceptable salt thereof; pharmaceutical compositions containing at least one of these compounds; methods of making at least one of these compounds; methods of using at least one of these compounds for treating and/or preventing various cancers and/or proliferation disorders; methods of using at least one of these compounds for monitoring the effectiveness of an anticancer therapy against various cancers. In one embodiment, the subject matter relates to compounds that bind with a level of specificity to heat shock protein 70 (Hsp70). In another embodiment, the subject matter relates to compounds that bind with a level of specificity to inhibit both heat shock protein 70 (Hsp70) and heat shock cognate protein 70 (Hsc70).Type: GrantFiled: August 17, 2010Date of Patent: February 14, 2017Assignee: Memorial Sloan-Kettering Cancer CenterInventors: Gabriela Chiosis, Tony Taldone, Anna Rodina, Pallav Patel, Yanlong Kang
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Publication number: 20140113821Abstract: A method of preparing a hydrogel for delivery of an active agent. The method includes providing an aqueous solution that includes the active agent; dispersing or dissolving a gel-forming polymer in the aqueous solution to form a polymer solution; and cross-linking the polymer in the polymer solution to form the hydrogel which encapsulates the active agent.Type: ApplicationFiled: June 1, 2012Publication date: April 24, 2014Inventors: Frank Gu, Mohit Singh Verma, Drew William Davidson, Benjamin Charles Lehtovaara
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Publication number: 20140018241Abstract: This invention provides polynucleotide molecules and methods for regulating genes in plants, e.g., by providing RNA for systemic regulation of genes. Various aspects of the invention provide polynucleotide molecules and methods for regulating endogenous genes and transgenes in a plant cell and polynucleotide molecules.Type: ApplicationFiled: August 30, 2013Publication date: January 16, 2014Applicant: Monsanto Technology LLCInventors: Robert D Sammons, Sergey Ivashuta, Hong Liu, Dafu Wang, Paul C. C. Feng, Andrei Y. Kouranov, Scott E. Andersen
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Publication number: 20110296556Abstract: This invention provides polynucleotide molecules and methods for regulating genes in plants, e.g., by providing RNA for systemic regulation of genes. Various aspects of the invention provide polynucleotide molecules and methods for regulating endogenous genes and transgenes in a plant cell and polynucleotide molecules.Type: ApplicationFiled: March 8, 2011Publication date: December 1, 2011Inventors: ROBERT D. SAMMONS, SERGEY IVASHUTA, HONG LIU, DAFU WANG, PAUL C. C. FENG, ANDREI Y. KOURANOV, SCOTT E. ANDERSEN
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Publication number: 20110130286Abstract: Piperazine compounds of the formula I in which the variables are defined according to the description, their agriculturally suitable salts, processes and intermediates for preparing the piperazine compounds of the formula I, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidally effective amount of at least one piperazine compound of the formula I to act on plants, their seed and/or their habitat.Type: ApplicationFiled: July 23, 2009Publication date: June 2, 2011Applicant: BASF SEInventors: Liliana Parra Rapado, Eike Hupe, Matthias Witschel, Thomas Seitz, Anja Simon, Robert Reinhard, Bernd Sievernich, Klaus Grossmann, Thomas Ehrhardt, Trevor William Newton, Frank Stelzer, Tao Qu, William Karl Moberg, Dschun Song, Michael Rack, Timo Frassetto, Klaus Kreuz, Julia Major
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Publication number: 20110088106Abstract: Hypercellular nonhuman organisms have functionally inactivated expression of a cyclin inhibitor gene, especially p27. The growth rate of nonhuman organisms are increased such that a desired size is attained more quickly than as compared to nonvariant organisms. Inhibitors of the p27 cyclin dependent kinase inhibitor protein or sequences encoding the protein modulate vertebrate cell cycle progression and increase the proportion of dividing cells to non-dividing cells in a population of treated cells. As the proportion of dividing cells increases, the cell population, e.g., hematopoietic progenitor (stem) cells, is more efficiently used for gene therapy applications. Transgenic animals and plants, and knockout alleles are provided.Type: ApplicationFiled: July 14, 2009Publication date: April 14, 2011Applicant: Fred Hutchinson Cancer Research CenterInventors: James M. Roberts, Steven R. Coats, Matthew L. Fero
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Publication number: 20100113273Abstract: There are provided an antidesiccant containing a nucleic acid as an active ingredient which codes for a heat shock protein originating from a salt tolerant cyanobacteria, an antidesiccant containing a nucleic acid which codes for a protein selected from a protein/enzyme relating to a photonic synthesis control, a protein/enzyme controlling the size of a plant body, a protein/enzyme promoting extension of a root, a protein/enzyme promoting growth of a plant body, and a protein/enzyme improving the stability of an RNA, or containing the antisense sequence thereof, a method of using the antidesiccant for making photonic synthesis more efficient, and a transpiration suppression method for a plant.Type: ApplicationFiled: March 26, 2008Publication date: May 6, 2010Applicant: SCIVAX CORPORATIONInventors: Tetsuko Takabe, Teruhiro Takabe, Akio Uchida
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Publication number: 20100105557Abstract: The present invention relates to novel active substance combinations which comprise firstly a known herbicide selected from among glyphosate derivatives, cyclohexenone oximes, imidazolinone derivatives, dinitroaniline derivatives, amide derivatives and quaternary ammonium salts, and at least one fungicidal active substance, and which are suitable for controlling undesirable phytopathogenic fungi, in particular soybean rust.Type: ApplicationFiled: March 5, 2008Publication date: April 29, 2010Inventors: Christine Habicher, Michael Merk, Egon Haden
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Publication number: 20090209422Abstract: Certain substituted aminoalkyl heteroaryl and heterocyclyl derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula I: wherein R, R1, R2, R3 and R4 are folly described herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula I, and optionally, an effective amount of at least one of an additional compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.Type: ApplicationFiled: May 2, 2006Publication date: August 20, 2009Applicant: Bayer CropScience AGInventors: John A. Dixson, George Theodoridis, Zeinab M. Elshenawy, Benjamin J. Dugan, Manorama M. Patel, John W. Lyga, Stephen F. Donovan, Ping Ding
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Publication number: 20030148887Abstract: A process for the preparation of a solvent-free suspension of a low-melting point water-insoluble solid agrochemical active ingredient, which comprises suspending 1-40% by weight of a silica-based carrier in 40 to 97% by weight of water in the presence of 1-40% by weight of anionic dispersant, heating the suspension thus obtained to a temperature above that of the active ingredient, and adding, with stirring, 1-25% by weight of a molten active ingredient with a melting point of <80° C. or a mixture of at least two active ingredients each having a melting point of <80° C. The present invention furthermore relates to the preparation of suspension concentrates, water-dispersible powders and water-dispersible granules based on the suspensions prepared via the abovementioned process.Type: ApplicationFiled: December 16, 2002Publication date: August 7, 2003Inventors: Matthias Bratz, Karl-Friedrich Jager
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Publication number: 20020160916Abstract: The invention pertains to new composition and a method for increasing the solubility of various agricultural compounds in water at a low pH. The compounds included in this patent are typically not soluble at pH ranges less than 7 to produce commercially viable liquid concentrates. This method requires the use of amine-containing surfactants and organic acids to lower the pH of various compounds and also keep them soluble in water.Type: ApplicationFiled: February 20, 2002Publication date: October 31, 2002Inventors: Greg Volgas, Johnnie R. Roberts, Amanda Hayes
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Publication number: 20010044383Abstract: It consists of using a precursor compound of cyclic AMP, or an inhibitor compound of the enzymes of the Phosphodiesterases family, or a stimulating compound of the enzymes of the Adenyl-Cyclase family, or an agonist compound of the &bgr;-adrenergic receptors to which arachidonic acid or a prostaglandin is added. The composition object of the invention can be presented mixed with mineral fertilizers (such as amonic nitrate, monopotassium phosphate, etc.), with phytoregulators (such as cytoquinines, auxines, giberelines, polyamines, n-ethanolamines, sugars . . . ) or with any type of phytosanitary product (such as fungicides, herbicides etc.). The composition object of the invention can be formulated with tensoactive agents (such as Tween 80), moistening agents etc. The composition object of the invention can be applied to any species of plant and at any point in its life cycle.Type: ApplicationFiled: April 10, 2001Publication date: November 22, 2001Applicant: INABONOS S.A.Inventors: Josemaria Garcia-Mina Freire, Santiago Cenoz Imaz
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Patent number: 6297194Abstract: Pyrazole compounds with activity as chemical hybridizing agents and methods for synthesis of such compounds are disclosed. These compounds are useful in producing hybrid wheat (Triticum aesativum) and other crops.Type: GrantFiled: February 2, 2000Date of Patent: October 2, 2001Assignee: Monsanto Technology, LLCInventors: Paula C. Miller, Jane M. Curtis, John M. Molyneaux, Thomas J. Owen
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Patent number: 6060432Abstract: Compounds of Formula I, and their N-oxides and agriculturally suitable salts, are disclosed which are useful for controlling undesired vegetation ##STR1## wherein X, Y, J, R.sup.1, and R.sup.2 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and a method for controlling undesired vegetation which involves contacting the vegetation or its environment with an effective amount of a compound of Formula I.Type: GrantFiled: October 24, 1996Date of Patent: May 9, 2000Assignees: E. I. du Pont de Nemours and Company, Degussa AktiengesellschaftInventors: Edward John Adams, Karlheinz Drauz, Wonpyo Hong, Balreddy Kamireddy, Wallace Christian Petersen, Matthias Schaefer, Christoph Weckbecker
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Patent number: 5922644Abstract: A herbicidal compound of formula (I) ##STR1## or a salt, tautomer or cyclic derivative thereof; where R.sup.1 and R.sup.2 are hydrogen and A is an optionally substituted saturated or unsaturated chain or ring of three carbon atoms.Methods for preparing these compounds, intermediates used in the preparation and herbicidal compositions containing them are also described and claimed.Type: GrantFiled: September 28, 1994Date of Patent: July 13, 1999Assignee: Zeneca LimitedInventors: John Michael Cox, Peter Bellini, Roger Barrett, Russell Martin Ellis, Timothy Robert Hawkes
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Patent number: 5854179Abstract: Sulfur-substituted phenylsulfonylureas; processes for their preparation and their use as herbicides and plant growth regulatorsCompounds of the formula (I) and salts thereof ##STR1## in which R*, R.sup.1, R.sup.2, R.sup.3, X, Y, Z, W, n and m are defined as in claim 1, and specifically R* is a formyl equivalent of the formula CHO, --CH.dbd.NR or CH(X.sup.1 R')(X.sup.2 R"), are suitable as herbicides and plant growth regulators. They are prepared analogously to known methods, in some cases using novel intermediate products of the formula (XVII) ##STR2## in which U*.dbd.NH.sub.2, Cl or (substituted) amino.Type: GrantFiled: November 3, 1995Date of Patent: December 29, 1998Assignee: Hoechst Schering AgrEvo GmbHInventors: Gerhard Schnabel, Lothar Willms, Klaus Bauer, Hermann Bieringer, Christopher Rosinger
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Patent number: 5707930Abstract: Herbicidal 4-cycloalkyl-5-substituted pyrimidine compounds of the formula ##STR1## are described. Herbicidal compositions containing such substituted-pyrimidinyl compounds and methods of controlling undesirable vegetation employing these compounds are also disclosed. The compounds in which XR, is hydroxyl are also useful as intermediates for producing the disclosed substituted-pyrimidinyl derivatives.Type: GrantFiled: September 16, 1996Date of Patent: January 13, 1998Assignee: Zeneca LimitedInventors: Raymond A. Felix, Hsiao-Ling M. Chin, Frank X. Woolard, David L. Lee, David B. Kanne
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Patent number: 5693590Abstract: This invention pertains to compositions comprising herbicidal phosphosulfonates, having the general formula ##STR1## wherein Y is an optionally substituted phenyl, naphthyl, benzyl, a (C.sub.5 -C.sub.8)cycloalkyl, a 5-membered heteroaromatic ring, a 6-membered heteraromatic ring, a fused 5,6-membered heteroaromatic ring, or a fused 6,6-membered heteroaromatic ring;X is an oxygen or a sulfur atom; andR.sup.1 and R.sup.2 are each independently selected from substituted or unsubstituted alkyl, alkoxy, alkylthio, alkenyloxy, alkynyloxy, haloalkoxy, cyanoalkoxy, alkoxyalkoxy, cycloalkyloxy, cycloalkylalkoxy, alkylideneiminooxy, chloro, amino, phenyl or phenoxy; or R.sup.1 and R.sup.2 are both alkoxy, taken together with the phosphorus atom to form a 6-membered oxygen-containing ring; anddichloroacetamide safeners having the general formula ##STR2## wherein R.sup.a and R.sup.b are each independently selected from alkyl, alkenyl, or alkyl or alkenyl substituted with halo, or R.sup.a and R.sup.Type: GrantFiled: July 20, 1995Date of Patent: December 2, 1997Assignee: Rohm and Haas CompanyInventors: James Delbert Fisher, Ernest Leroy Burdge, Vincent Angelo Musco, Jr., Lori Ann Spangler
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Patent number: 5661107Abstract: Compounds of the formula ##STR1## wherein m represents 1 or 2, X represents O, S, CH.sub.2 or substituted CH.sub.2, R.sub.1 -R.sub.4 represent hydrogen or substituted or unsubstituted hydrocarbon groups, and Q represents a substituted phenyl group. These compounds are useful as herbicides and are active in small doses with high selectivity between useful plants and weeds.Type: GrantFiled: April 13, 1995Date of Patent: August 26, 1997Assignee: Degussa AktiengesellschaftInventors: Matthias Schafer, Karlheinz Drauz
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Patent number: 5622917Abstract: The invention relates to new 1H-3-aryl-pyrrolidine-2,4-dione derivatives of the formula (I) ##STR1## in which A, B, X, Y and G have the meanings given in the description, to a plurality of processes for their preparation, and to their use as pesticides.Type: GrantFiled: January 3, 1995Date of Patent: April 22, 1997Assignee: Bayer AktiengesellschaftInventors: Reiner Fischer, Thomas Bretschneider, Bernd-Wieland Kr uger, Michael Ruther, Christoph Erdelen, Ulrike Wachendorff-Neumann, Hans-Joachim Santel, Markus Dollinger
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Patent number: 5605877Abstract: Compounds of Formula I are disclosed which are useful for controlling undesired vegetation ##STR1## wherein Q is ##STR2## and W, R.sup.A.sub.m, R.sup.4 -R.sup.8 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula I and a method for controlling undesired vegetation which involves contacting the vegetation or its environment with an effective amount of a compound of Formula I.Type: GrantFiled: March 10, 1995Date of Patent: February 25, 1997Assignee: E. I. Du Pont de Nemours and CompanyInventors: Matthias Schafer, Karlheinz Drauz, Dieter Feit, Kofi S. Amuti
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Patent number: 5604181Abstract: Herbicidal compounds of formula (I) and salts thereof, where A is --N.dbd. or --CH.dbd.; X is --OH, --OR.sup.10, --SH, --SR.sup.10, --SCN, NH.sub.2, --NHacyl, --CH.sub.2 OH, --CH.sub.2 OR.sup.9 or --CN; R.sup.1 and R.sup.2, which may be the same or different, each represent alkyl, alkoxy, haloalkyl, haloalkoxy, halo, alkylamino or dialkylamino; R.sup.3 is --CN, --COOR.sup.5, --CONR.sup.6 R.sup.7, --CSNH.sub.2, --CHO, --CH.dbd.Z, --CH(Oalkyl).sub.2, --CH.sub.2 OH, --CH.sub.2 OR.sup.9, --COSR.sup.4a, --CS.sub.2 R.sup.4a, or a substituted or unsubstituted 5- or 6-membered heterocyclic group linked via a ring carbon atom which is between two ring heteroatoms; R.sup.4 and R.sup.4a, which may be the same or different, are each H, or a substituted or unsubstituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, aralkyl or heteroaryl group; R.sup.Type: GrantFiled: March 8, 1995Date of Patent: February 18, 1997Assignee: Agrevo UK LimitedInventors: Thomas L. Hough, Peter S. Gates
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Patent number: 5556840Abstract: Optically active compounds of the formula ##STR1## wherein n is 1 or 2 and m is 0, 1, 2 or 3 have antiviral activity. Compounds of the formula wherein at least one of the internecleotide phosphorothioate linkages is of the Sp configuration possess increased antiviral activity and/or metabolic stability.Type: GrantFiled: December 2, 1994Date of Patent: September 17, 1996Assignee: Temple University - Of The Commonwealth System of Higher EducationInventors: Robert J. Suhadolnik, Wolfgang Pfleiderer
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Patent number: 5552369Abstract: The invention relates to new sulphonylaminocarbonyltriazolinones of the formula (I) ##STR1## in which Q represents oxygen, sulphur or one of the following groups ##STR2## (in which the radicals R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meanings given in the description),as well as to salts of compounds of the formula (I), to processes and novel intermediates for the preparation of the novel compounds, and to their use as herbicides.Type: GrantFiled: April 7, 1995Date of Patent: September 3, 1996Assignee: Bayer AktiengesellschaftInventors: Kurt Findeisen, Karl-Heinz Linker, Joachim Kluth, Klaus-Helmut M uller, Hans-Jochem Riebel, Klaus K onig, Hans-Joachim Santel, Robert R. Schmidt
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Patent number: 5512535Abstract: This invention relates to herbicidal pyridinesulfonylureas which are highly active as preemergence and postemergence herbicides.Type: GrantFiled: December 8, 1994Date of Patent: April 30, 1996Assignee: E. I. Du Pont de Nemours and CompanyInventor: Paul Hsiao-Tseng Liang
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Patent number: 5500405Abstract: This invention pertains to phosphosulfonates, having the general formula ##STR1## wherein Y is phenyl, naphthyl, benzyl, a (C.sub.5 -C.sub.8)cycloalkyl, a 5-membered heteroaromatic ring, a 6-membered heteraromatic ring, a fused 5,6-membered heteroaromatic ring, or a fused 6,6-membered heteroaromatic ring; andX is oxygen or sulfur; andR.sup.1 and R.sup.2 are each independently selected from substituted or unsubstituted alkyl, alkoxy, alkylthio, alkenyloxy, alkynyloxy, haloalkoxy, cyanoalkoxy, alkoxyalkoxy, cycloalkyloxy, cycloalkylalkoxy, alkylideneiminooxy, chloro, amino, phenyl or phenoxy; or R.sup.1 and R.sup.2 are both alkoxy, taken together with the phosphorus atom to form a 6-membered oxygen-containing ring; compositions containing these compounds and their use as herbicides.Type: GrantFiled: September 22, 1993Date of Patent: March 19, 1996Assignee: Rohm and Haas CompanyInventors: Robert E. Rosen, Damian G. Weaver, Jane W. Cornille, Lori A. Spangler
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Patent number: 5482920Abstract: Pyrimidinyloxy- and triazinyloxy- and pyrimidinylthio- and triazinylthio-butyric acid derivatives of formula I ##STR1## wherein Q is ##STR2## A is hydroxy or a group ##STR3## and the other substituents are as described in patent claim 1, and salts of compounds of formula I, have herbicidal action and are suitable as active ingredients in weed control compositions.Type: GrantFiled: February 15, 1994Date of Patent: January 9, 1996Assignee: Ciba-Geigy CorporationInventor: Christoph Luthy
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Patent number: 5476946Abstract: The invention relates to new 1-aryltriazolin(ethi)ones of the general formula (I) ##STR1## in which R.sup.1 represents nitro or represents a radical --NR.sup.8 R.sup.9,R.sup.2 represents hydrogen, amino or cyano, or represents one of the radicals --R.sup.10, --O--R.sup.10, --S--R.sup.10, --NR.sup.10 R.sup.11, --N(R.sup.11)--CO--R.sup.10 or --N.dbd.CR.sup.10 R.sup.11,R.sup.3, R.sup.6 and R.sup.7 independently of one another each represent hydrogen, halogen or nitro,R.sup.4 represents hydrogen, halogen, cyano or nitro, or represents one of the radicals --R.sup.12, --O--R.sup.12, --S--R.sup.12, --S(O)--R.sup.12, --SO.sub.2 --R.sup.12, --SO--OR.sup.12, --SO--NR.sup.11 R.sup.12, --CO--OR.sup.12, --CO--NR.sup.11 R.sup.12, --O--SO.sub.2 --R.sup.12, --N(R.sup.11)--SO.sub.2 --R.sup.12, --NR.sup.11 R.sup.12, --NH--P(O)(R.sup.11)(OR.sup.12) or --NH--P(O)(OR.sup.11)(OR.sup.12),R.sup.5 represents nitro, cyano, halogen or halogenoalkyl, andX represents oxygen or sulphur, whereR.sup.8 and R.sup.Type: GrantFiled: February 2, 1994Date of Patent: December 19, 1995Assignee: Bayer AktiengesellschaftInventors: Karl-Heinz Linker, Kurt Findeisen, Wilhelm Haas, Otto Schallner, Markus Dollinger, Hans-Joachim Santel
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Patent number: 5474974Abstract: There are provided new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) ##STR1## The new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) have a particularly pronounced activity against animal pests, in particular against insects and arachnids, and against weeds.Type: GrantFiled: April 28, 1994Date of Patent: December 12, 1995Assignee: Bayer AktiengesellschaftInventors: Bernd-Wieland Kruger, Reiner Fischer, Heinz-Jurgen Bertram, Thomas Bretschneider, Stefan Bohm, Andreas Krebs, Thomas Schenke, Hans-Joachim Santel, Klaus Lurssen, Robert R. Schmidt, Christoph Erdelen, Ulrike Wachendorff-Neumann, Wilhelm Stendel
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Patent number: 5446013Abstract: Pyrimidinyl- or triazinyloxy- (or -thio)-carboxylic acid derivatives, processes for their preparation, and their use as herbicides or plant growth regulatorsCompounds of the formula (I) ##STR1## in which A is ##STR2## and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, X and Y are as defined in claim 1 are suitable as selective herbicides and plant growth regulators.Type: GrantFiled: December 17, 1993Date of Patent: August 29, 1995Assignee: Hoechst AktiengesellschaftInventors: Frank Zurmuhlen, Klaus Bauer, Hermann Bieringer
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Patent number: 5439874Abstract: The invention relates to novel substituted bicyclo[3.1.0]hexanes of the formula ##STR1## in which R.sup.1 represents, e. g., hydroxyl or alkoxy,R.sup.2 to R.sup.8 represent, e. g., hydrogen or alkyl,R.sup.9 and R.sup.10 represent, e.g., methyl or methoxy,X represents, e.g., oxygen,Y represents, e.g., oxygen or sulphur andZ represents, e.g., CH or N,as well as salts of the free acid (R.sup.1 =OH) and their further functional derivatives, and furthermore to processes and novel intermediates for their preparation, and to their use as herbicides.In addition, a novel process is described for preparing certain 2-keto-bicyclo[3.1.0]hexanes, which are required as intermediates, starting from correspondingly substituted .alpha.,.beta.-unsaturated carbonyl compounds (of the methacrolein type) and .beta.-keto acid esters (of the acetoacetic acid ester type).Type: GrantFiled: July 21, 1993Date of Patent: August 8, 1995Assignee: Bayer AktiengesellschaftInventors: Mark W. Drewes, Rolf Kirsten, Hans-Joachim Santel, Klaus Lurssen, Robert R. Schmidt
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Patent number: 5393732Abstract: A herbicidal compound of formula (I) ##STR1## or a salt, tautomer or cyclic derivative thereof; where R.sup.1 and R.sup.2 are hydrogen and A is an optionally substituted saturated or unsaturated chain or ring of three carbon atoms.Methods for preparing these compounds, intermediates used in the preparation and herbicidal compositions containing them are also described and claimed.Type: GrantFiled: January 21, 1993Date of Patent: February 28, 1995Assignee: Zeneca LimitedInventors: John M. Cox, Peter Bellini, Roger Barrett, Russell M. Ellis, Timothy R. Hawkes
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Patent number: 5393733Abstract: This invention relates to herbicidal pyridinesulfonylureas which are highly active as preemergence and postemergence herbicides.Type: GrantFiled: April 27, 1993Date of Patent: February 28, 1995Assignee: E. I. Du Pont de Nemours and CompanyInventor: Paul H. Liang
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Patent number: 5358924Abstract: There are provided new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) ##STR1## in which A and B are identical or different and independently of one another in each case represent hydrogen, alkyl, alkenyl, alkynyl, alkoxyalkyl, alkythioalkyl, cycloalkyl or optionally substituted aryl orA and B together represent the bivalent radical of a saturated or unsaturated, optionally substituted, mono-, bi-, tri- or polycyclic system,X represents alkyl, halogen or alkoxy,Y represents hydrogen, alkyl, halogen, alkoxy or halogenoalkyl,Z represents alkyl, halogen or alkoxy,n represents a number 0, 1, 2 or 3,G represents hydrogen (a) or the groups ##STR2## in which E represents a metal ion equivalent or an ammonium ion,L and M represents oxygen and/or sulphur,and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 have the meaning given in the text of the application.Type: GrantFiled: December 31, 1992Date of Patent: October 25, 1994Assignee: Bayer AktiengesellschaftInventors: Bernd-Wieland Kruger, Reiner Fischer, Heinz-Jurgen Bertram, Thomas Bretschneider, Stefan Bohm, Andreas Krebs, Thomas Schenke, Hans-Joachim Santel, Klaus Lurssen, Robert R. Schmidt, Christoph Erdelen, Ulrike Wachendorff-Neumann, Wilhelm Stendel
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Patent number: 5354727Abstract: 2-(1-Substituted-2-imidazolin-2-yl)benzoic and nicotinic acids, and derivatives thereof, which are effective in the control of undesirable plant species are described, Also described are a method for the herbicidal use of the compounds and a method for their preparation.Type: GrantFiled: January 26, 1993Date of Patent: October 11, 1994Assignee: American Cyanamid CompanyInventor: Michael A. Guaciaro
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Patent number: 5290755Abstract: Salicylic acid derivatives and sulfur analogs thereof of the formula I, ##STR1## wherein the substituents are herein below defined.Type: GrantFiled: August 4, 1992Date of Patent: March 1, 1994Assignee: BASF AktiengesellschaftInventors: Uwe J. Vogelbacher, Joachim Rheinheimer, Thomas Saupe, Norbert Meyer, Matthias Gerber, Karl-Otto Westphalen, Helmut Walter
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Patent number: 5272128Abstract: This invention pertains to phosphosulfonates, having the general formula ##STR1## wherein Y is phenyl, naphthyl, benzyl, a (C.sub.5 -C.sub.8)cycloalkyl, a 5-membered heteroaromatic ring, a 6-membered heteraromatic ring, a fused 5,6-membered heteroaromatic ring, or a fused 6,6-membered heteroaromatic ring; andX is oxygen or sulfur; andR.sup.1 and R.sup.2 are each independently selected from substituted or unsubstituted alkyl, alkoxy, alkylthio, alkenyloxy, alkynyloxy, haloalkoxy, cyanoalkoxy, alkoxyalkoxy, cycloalkyloxy, cycloalkylalkoxy, alkylideneiminooxy, chloro, amino, phenyl or phenoxy; or R.sup.1 and R.sup.2 are both alkoxy, taken together with the phosphorus atom to form a 6-membered oxygen-containing ring; compositions containing these compounds and their use as herbicides.Type: GrantFiled: April 1, 1992Date of Patent: December 21, 1993Assignee: Rohm and Haas CompanyInventors: Robert E. Rosen, Damian G. Weaver, Jane W. Cornille, Lori A. Spangler
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Patent number: 5248655Abstract: A triazole of the formula I ##STR1## in which the meanings of the radicals are described in claim 1, have a herbicidal and plant-growth regulating action. They are suitable as active substances in weed killers and in compositions for positively influencing the growth of crop plants.Type: GrantFiled: August 7, 1992Date of Patent: September 28, 1993Assignee: Japat Ltd.Inventors: Kenji Hayakawa, Ichiro Mori, Genji Iwasaki, Shin-Ichiro Matsunaga
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Patent number: 5246914Abstract: Salicyloyl(thio)ether derivatives of the formula I, ##STR1## where is oxygen or sulfur and Z is carbon or nitrogen, and the radicals R.sup.1 to R.sup.4 and A have the meanings given in the disclosure, and processes and intermediates for preparing compounds I.Type: GrantFiled: August 7, 1992Date of Patent: September 21, 1993Assignee: BASF AktiengesellschaftInventors: Uwe J. Vogelbacher, Joachim Rheinheimer, Thomas Saupe, Norbert Meyer, Matthias Gerber, Karl-Otto Westphalen, Helmut Walter
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Patent number: 5217523Abstract: Pyrazole-3-carboxamides of the general formula I ##STR1## where the substituents have the following meaning: R.sup.1 hydrogen;substituted or unsubstituted C.sub.3 -C.sub.8 -cycloalkyl or C.sub.1 C.sub.6 -alkyl;R.sup.2 hydroxy; amino; C.sub.1 -C.sub.4 -alkylamino; di-C.sub.1 -C.sub.4 -alkylamino, aminocarbonyl-C.sub.1 -C.sub.6 -alkyl; substituted or unsubstituted C.sub.1 -C.sub.4 -alkoxy, C.sub.3 -C.sub.6 -alkenyl, C.sub.3 -C.sub.6 -alkynyl, phenyl or naphthyl,a substituted or unsubstituted 5- to 6-membered heterocyclic ring;one of the groups mentioned for R.sup.1 orR.sup.1 and R.sup.2 together denote a 4- to 7-membered chain which may contain, in addition to methylene groups one of the following groups as ring member: oxygen, sulfur N-methyl or carbonyl;R.sup.3 a substituted or unsubstituted 5- to 6-membered heterocyclic ring.substituted or unsubstituted C.sub.3 -C.sub.6 -alkenyl, C.sub.3 -C.sub.6 alkynyl, 5,6,7,8-tetrahydronaphthyl or phenyl orone of the groups mentioned for R.sup.1 ;R.sup.Type: GrantFiled: May 4, 1992Date of Patent: June 8, 1993Assignee: BASF AktiengesellschaftInventors: Klaus Ditrich, Gerhard Hamprecht, Peter Plath, Bruno Wuerzer, Karl-Otto Westphalen
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Patent number: 5215569Abstract: Substituted pyridines of the formula ##STR1## in which A represents nitrogen or a C-X group where X represents hydrogen or halogen,Q represents oxygen or sulphur,R.sup.1 and R.sup.2 are identical or different and represent hydrogen, halogen, alkyl, halogenoalkyl, alkoxyalkyl, alkoxy, halogenoalkoxy, alkylthio, alkylamino or dialkylamino,R.sup.3 represents hydrogen, amino, nitro, hydroxyl, halogen, alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, alkylamino, dialkylamino, alkylcarbonylamino, alkoxycarbonylamino or alkysulphonylamino,R.sup.4 represents hydrogen or alkyl andZ represents oxygen or one of the groups below: ##STR2## where R.sup.5, R.sup.6 and R.sup.7 are defined herein and their use in herbicide compositions.Type: GrantFiled: July 31, 1991Date of Patent: June 1, 1993Assignee: Bayer AktiengesellschaftInventors: Mark W. Drewes, Peter Muller, Hans-Joachim Santel, Klaus Lurssen, Robert R. Schmidt
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Patent number: 5213607Abstract: 2-(1-Substituted-2-imidazolin-2-yl)benzoic and nicotinic acids, and derivatives thereof, which are effective in the control of undesirable plant species are described. Also described are a method for the herbicidal use of the compounds and a method for their preparation.Type: GrantFiled: September 19, 1991Date of Patent: May 25, 1993Assignee: American Cyanamid CompanyInventor: Michael A. Guaciaro
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Patent number: 5188642Abstract: This invention involves a cloning or expression vector comprising a gene which encodes 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) polypeptide which, when expressed in a plant cell contains a chloroplast transit peptide which allows the polypeptide, or an enzymatically active portion thereof, to be transported from the cytoplasm of the plant cell into a chloroplast in the plant cell, and confers a substantial degree of glyphosate resistance upon the plant cell and plants regenerated therefrom.The EPSPS coding sequence may be ligated to a strong promoter, such as the 35S promoter from cauliflower mosaic virus, to create a chimeric gene. Such genes can be inserted into plant transformation vectors, and subsequently introduced into plant cells. Plant cells transformed using such genes and plants regenerated therefrom have been shown to exhibit a substantial degree of glyphosate resistance.Type: GrantFiled: February 12, 1990Date of Patent: February 23, 1993Assignee: Monsanto CompanyInventors: Dilip M. Shah, Stephen G. Rogers, Robert B. Horsch, Robert T. Fraley
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Patent number: 5186734Abstract: Herbicidal bisazinyl compounds of the formula ##STR1## in which A.sup.1 and A.sup.2 are identical or different and represent nitrogen or a C--X group, X representing hydrogen, halogen, alkyl or alkoxy, andQ.sup.1 and Q.sup.2 are identical or different and represent oxygen, sulphur, NH or N-alkyl,(the substituents R, X.sup.1, X.sup.2, Y.sup.1, Y.sup.2 and Z representing a variety of organic radicals).The compounds of the formulas ##STR2## are also new.Type: GrantFiled: September 11, 1991Date of Patent: February 16, 1993Assignee: Bayer AktiengesellschaftInventors: Roland Andree, Mark W. Drewes, Hans-Joachim Santel, Klaus Lurssen, Robert R. Schmidt
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Patent number: 5185025Abstract: The present invention relates to certain novel substituted 3-phenoxypyrazoles and their use as herbicides.Type: GrantFiled: October 13, 1989Date of Patent: February 9, 1993Assignee: Monsanto CompanyInventors: Kurt Moedritzer, Michael D. Rogers
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Patent number: 5185026Abstract: Herbicidal naphthalene derivatives of the formula ##STR1## in which Q represents oxygen, sulphur or the group NR, where R represents hydrogen or alkyl,R.sup.1 represents hydrogen or alkylR.sup.2, R.sup.3 and R.sup.4 are identical or different and in each case represent hydrogen or another radical,R.sup.5 represents hydrogen or halogen, or represents in each case optionally substituted alkyl, alkoxy, alkylthio, alkylamino or dialkylamino,R.sup.6 represents hydrogen or halogen, or represents in each case optionally substituted alkyl or alkoxy, andR.sup.7 represents hydrogen or halogen, or represents in each case optionally substituted alkyl, alkoxy, alkylthio, alkylamino or dialkylamino, andZ represents N--R.sup.Type: GrantFiled: April 4, 1991Date of Patent: February 9, 1993Assignee: Bayer AktiengesellschaftInventors: Mark W. Drewes, Michael Haug, Klaus Lurssen, Hans-Joachim Santel, Robert R. Schmidt
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Patent number: 5183492Abstract: The invention is concerned with compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 have the significances given in the description, as well as enol ethers and salts thereof and their manufacture. The compounds have herbicidal properties and are accordingly suitable as active ingredients of weed control compositions. The invention is also concerned with weed control compositions containing one or more of such substances and with the use of the substances or compositions for the control of weeds.Type: GrantFiled: February 27, 1991Date of Patent: February 2, 1993Assignee: Ciba-Geigy CorporationInventors: Milos Suchy, Paul Winternitz, Martin Zeller
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Patent number: RE34779Abstract: A pyrazole derivative of the formula I ##STR1## wherein A is C.sub.1 -C.sub.4 alkyl, C.sub.2 -C.sub.4 alkenyl or C.sub.2 -C.sub.4 alkynyl; B is hydrogen, C.sub.1 -C.sub.3 alkyl, halogen, C.sub.1 -C.sub.3 haloalkyl, C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio, C.sub.2 -C.sub.4 alkoxyalkyl, C.sub.2 -C.sub.4 alkylthioalkyl or C.sub.2 -C.sub.4 alkoxycarbonyl; X is C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, halogen, nitro, cyano, etc.; Y is --OR.sup.1 (wherein R.sup.1 is C.sub.3 -C.sub.8 cycloalkyl, etc), --O--L--O--R.sup.1 (wherein L is C.sub.1 -C.sub.6 alkylene which may be substituted by C.sub.1 -C.sub.3 alkyl), --O--L--OH, --O--L--O--L--O--R.sup.2 (wherein R.sup.2 is hydrogen, C.sub.1 -C.sub.6 alkyl group, etc.), --O--L--R.sup.3 (wherein R.sup.3 is phenyl which may be substituted by C.sub.1 -C.sub.3 alkyl, etc.), --O--M (wherein M is a 3- to 6-membered alicyclic group), --O--L--M, --O--L--NR.sup.4 R.sup.5 (wherein each of R.sup.4 and R.sup.5 is hydrogen or C.sub.1 -C.sub.6 alkyl, or R.sup.Type: GrantFiled: September 18, 1992Date of Patent: November 8, 1994Assignee: Nissan Chemical Industries Ltd.Inventors: Eiichi Oya, Junichi Watanabe, Yasuo Kondo, Takuya Kakuta, Koichi Suzuki, Tsutomu Nawamaki, Shigeomi Watanabe