Enzyme Component Of Specific Activity Or Source (e.g., Protease, Of Bacterial Origin, Etc.) Patents (Class 510/392)
  • Patent number: 10470997
    Abstract: The present invention relates to a liquid cosmetic composition for making up and/or caring for the skin and/or the lips, comprising, in a physiologically acceptable medium, —at least one non volatile oil, —at least hydrophobic silica aerogel particles, —at least one wax with a melting point of greater than or equal to 60° C., —the said composition comprising less than 5% by weight of water relative to the total weight of the composition, and preferably being anhydrous.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: November 12, 2019
    Assignee: L'OREAL
    Inventors: Nathalie Julien, Sylvie Guillard
  • Patent number: 10407650
    Abstract: A detergent composition comprising a polypeptide having protease activity is disclosed. The composition may be used in laundry or hard surface cleaning such as automated dish wash, and it has improved performance compared with a commercial protease.
    Type: Grant
    Filed: May 1, 2013
    Date of Patent: September 10, 2019
    Assignee: NOVOZYMES A/S
    Inventors: Benie Astrid, Jeppe Wegener Tams, Peter Rahbek Oestergaard, Morten Gjermansen, Martin Simon Borchert
  • Patent number: 10106761
    Abstract: The present invention relates to a new metalloprotease and the use thereof in cleaning processes, such as laundry and dish wash. The invention also relates to detergent compositions and cleaning compositions comprising a metalloprotease.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: October 23, 2018
    Assignee: Novozymes A/S
    Inventors: Morten Gjermansen, Soeren Nymand-Grarup, Peter Rahbek Oestergaard, Anna Verena Reiser, Jeannette Bjerre
  • Patent number: 10066192
    Abstract: A detergent composition comprising a subtilisin variant having the amino acid sequence set forth in SEQ ID NO: 1, and at least one additional ingredient selected from i) bleaches selected from percarbonates, persulphates and organic peracids, ii) aminocarboxylates, or iii) sulphonated polymers, or iv) organophosphoric acids or salts thereof and mixtures thereof is provided. Also provided is a detergent composition comprising a subtilisin variant having the amino acid sequence set forth in SEQ ID NO: 1, wherein the detergent composition is at least partially enveloped in a water soluble or water dispersible package. The compositions exhibit good performance on proteinaceous stains, even when formulated at alkaline pHs. A method of removing proteinaceous stains from surfaces comprising such stains is also provided.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: September 4, 2018
    Assignee: RECKITT BENCKISER FINISH B.V.
    Inventors: Lucia Krubasik, Frank Dierkes, Steffen Lingler, Jörg Pflug
  • Patent number: 9828591
    Abstract: Described are compositions and methods relating to the thermostable fungal cellulase enzyme, EGV, and Trichoderma host cells having a modification comprising or consisting essentially of disruption or deletion of nucleotide(s) for expression of this cellulose, whereby EGV expression is prevented.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: November 28, 2017
    Assignee: DANISCO US INC
    Inventors: Andrei Miasnikov, Michael Schelle, Michael Ward
  • Patent number: 9738857
    Abstract: The present disclosure relates to compositions and methods for cleaning medical and dental instruments. The disclosed compositions are preferably non-foaming or generate low foam to allow visual inspection of the cleaning process as well as safe handling of the instruments. The disclosed compositions preferably employ select proteases, a carbonate and a nonionic surfactant.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: August 22, 2017
    Assignee: Ecolab USA Inc.
    Inventors: Nathan R. Ortmann, Katherine Vetter, Thomas R. Mohs, Anthony W. Erickson
  • Patent number: 9719055
    Abstract: A liquid cleaning agent containing: a) 20 to 70 wt % water, b) at least one amylase preparation, c) at least one Ca2+-ion source, d) lactic acid or a lactic acid salt, is notable for elevated amylase stability and improved cleaning performance.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: August 1, 2017
    Assignee: Henkel AG & Co. KGaA
    Inventors: Thomas Eiting, Dorota Sendor-Mueller, Johannes Zipfel, Arnd Kessler, Thorsten Bastigkeit, Christian Nitsch, Sven Mueller
  • Patent number: 9668476
    Abstract: This invention relates to a method for controlling microorganisms comprising coating a surface with a removable, antimicrobial film-forming composition.
    Type: Grant
    Filed: February 23, 2007
    Date of Patent: June 6, 2017
    Assignee: LANXESS Corporation
    Inventors: Helen S. M. Lu, Christian Lenges, Barry Stieglitz, Lynn Leger, Christian Hoffman, Judith J. Vangorp, Shaun F. Malone
  • Patent number: 9550984
    Abstract: Novel fungal endoglucanases Cel5 and Cel12 are disclosed. The endoglucanases are conveniently produced by recombinant technology, and means for their production are described. The endoglucanases are used for treating cellulosic material, especially in textile industry, e.g. in biofinishing or biostoning. They may also be used in detergents, in animal feed and/or in pulp and paper industry, or in hydrolysis of lignocellulosic material for, e.g. bioethanol production.
    Type: Grant
    Filed: October 18, 2013
    Date of Patent: January 24, 2017
    Assignee: AB Enzymes Oy
    Inventors: Terhi Puranen, Leena Valtakari, Marika Alapuranen, George Szakacs, Pentti Ojapalo, Jari Vehmaanperä
  • Patent number: 9528114
    Abstract: Certain aspects of this disclosure relate to a method of amplifying a genomic locus. In certain embodiments, the method may comprise: a) contacting a population of bacterial host cells with an inhibitor of an essential enzyme, where the bacterial host cells comprise a genomic locus of the structure: A1-P-M-A2, where A1 and A2 are direct repeats, P comprises a coding sequence for a polypeptide, and M comprises a coding sequence for the essential enzyme; and b) selecting for cells that are resistant to the inhibitor; wherein cells that are resistant to the inhibitor have multiple copies of the amplification unit.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: December 27, 2016
    Assignee: DANISCO US INC.
    Inventors: Eugenio Ferrari, Caroline M. Peres
  • Patent number: 9517189
    Abstract: The present invention relates to a cosmetic composition for making up and/or caring for the skin and/or the lips, comprising, in a physiologically acceptable medium, at least one oil, which is preferably non-volatile, at least hydrophobic silica aerogel particles, at least one hydrocarbon-based resin having a number-average molecular weight of less than or equal to 10 000 g/mol, the said composition comprising less than 5% by weight of water relative to the total weight of the composition, and preferably being anhydrous.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: December 13, 2016
    Assignee: L'OREAL
    Inventors: Stephane Arditty, Frederic Auguste, Virginie Perez Nowak
  • Patent number: 9403897
    Abstract: An object of the present invention is to provide proteinaceous protease inhibitors with moderate inhibitory activity.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: August 2, 2016
    Assignee: Sanyo Chemical Industries, Ltd.
    Inventors: Miki Kusano, Fusamitsu Yanagihara
  • Patent number: 9321873
    Abstract: A personal care composition includes a hybrid copolymer including at least one ethylenically unsaturated monomer and a naturally derived hydroxyl containing chain transfer agent as an end group, a hybrid synthetic copolymer including one or more synthetic polymers derived from the at least one ethylenically unsaturated monomer with at least one initiator fragment as an end group and an effective amount of a cosmetic or personal care additive.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: April 26, 2016
    Assignee: AKZO NOBEL N.V.
    Inventors: John S. Thomaides, Klin A. Rodrigues, Samuel A. Vona, Jr., Gary T. Martino, Anthony J. Adamo
  • Patent number: 9315791
    Abstract: The present invention relates to new metalloproteases derived from Alicyclobacillus and the use thereof in cleaning processes, such as laundry and dish wash, and in particular to the use in low temperature wash and in removal of egg stains. The invention also relates to detergent compositions and cleaning compositions comprising Alicyclobacillus sp. metalloproteases.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: April 19, 2016
    Assignee: NOVOZYMES A/S
    Inventors: Astrid Benie, Peter Rahbek Oestergaard, Morten Gjermansen
  • Patent number: 9138600
    Abstract: An oral care composition comprising a dye polymer, for modifying the color of teeth.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: September 22, 2015
    Assignee: Conopco, Inc.
    Inventors: Stephen Norman Batchelor, Andrew Joiner, Sheng Meng, Carole Jane Philpotts, Qingsheng Tao, Jinfang Wang
  • Publication number: 20150141316
    Abstract: Described are variants of alpha-amylase enzymes for use in industrial processes, such as liquefaction of starch. The alpha-amylase variants have increased specific activity allowing the more rapidly reduction of peak viscosity during liquefaction processes. The alpha-amylase is modified by introducing into the amino sequence of a parent Family 13 alpha-amylase polypeptide a mutation at an amino acid residue in the starch-binding groove; wherein the starch-binding groove is formed by amino acid residues in the alpha-helix preceding the first beta-strand in the A domain, the loop between the sixth alpha-helix and the seventh beta-strand in the A domain, the loop between the seventh alpha-helix and the eighth beta-strand in the A domain, and the loop connecting the A domain and the C domain; and wherein the mutation alters the binding of starch to the variant alpha amylase polypeptide compared to the parental alpha amylase polypeptide.
    Type: Application
    Filed: May 24, 2013
    Publication date: May 21, 2015
    Applicant: DANISCO US INC.
    Inventors: Richard R. Bott, Luis G. Cascao-Pereira, David A. Estell, Marc Kolkman, David E. Wildes
  • Publication number: 20150140165
    Abstract: The present invention relates to the use of isolated polypeptides having protease activity in animal feed and detergents. It also relates to the use of isolated nucleic acid sequences encoding the proteases in the recombinant production of isolated polypeptides having protease activity and isolated nucleic acid sequences encoding the proteases. The invention also relates to nucleic acid constructs, vectors, and host cells, including plant and animal cells, comprising the nucleic acid sequences, as well as methods for producing and using the proteases, particularly using the proteases in animal feed and detergents.
    Type: Application
    Filed: June 19, 2013
    Publication date: May 21, 2015
    Inventors: Tine Hoff, Robert Piotr Olinski, Carsten Sjoeholm, Peter Rahbek Oestergaard, Katrine Fruergaard Pontoppidan, Astrid Benie, Morten Gjermansen
  • Publication number: 20150132825
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 14, 2015
    Applicant: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulose, Brian F. Schmidt
  • Publication number: 20150132832
    Abstract: Stabilized use solutions of low phosphorus, alkali metal carbonate detergents employing enzymes for cleaning compositions are disclosed. In particular, the present invention is a composition for, and method of, removing soils, preventing redeposition of protein soils and reducing foam, using stabilized enzyme cleaning compositions, namely use solutions of the same.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 14, 2015
    Inventors: Wendy Chan, Jennifer Stokes, Lyndal Jensen, Carter M. Silvernail, Terrence P. Everson, Graig Legatt, Nathan Richard Ortmann, Devon Beau Hammel
  • Publication number: 20150132823
    Abstract: The invention relates to a variant of a parent Termamyl-like alpha-amylase, comprising mutations in two, three, four, five or six regions/positions. The variants have increased stability at high temperatures (relative to the parent). The invention also relates to a DNA construct comprising a DNA sequence encoding an alpha-amylase variant of the invention, a recombinant expression vector which carries a DNA construct of the invention, a cell which is transformed with a DNA construct of the invention, the use of an alpha-amylase variant of the invention for washing and/or dishwashing, textile desizing, starch liquefaction, a detergent additive comprising an alpha-amylase variant of the invention, a manual or automatic dishwashing detergent composition comprising an alpha-amylase variant of the invention, a method for generating a variant of a parent Termamyl-like alpha-amylase, which variant exhibits increased.
    Type: Application
    Filed: January 21, 2015
    Publication date: May 14, 2015
    Inventors: Allan Svendsen, Soren Kjaerulff, Henrik Bisgaard-Frantzen, Carsten Andersen
  • Publication number: 20150132831
    Abstract: The invention relates to a cleaning composition comprising a lipase with at least 75% identity to SEQ ID NO: 2, and a surfactant, wherein said composition is more effective in removing lipid stains present at a surface in comparison with an equivalent composition lacking the lipase.
    Type: Application
    Filed: May 15, 2013
    Publication date: May 14, 2015
    Inventors: Robert Piotr Olinski, Kim Borch, Anna Verena Reiser, Lone Baunsgaard, Carsten Hoerslev Hansen, Kenneth Jensen
  • Publication number: 20150132824
    Abstract: The present invention relates to isolated polypeptides having xanthan degrading activity, catalytic domains and polynucleotides encoding the polypeptides and catalytic domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides and catalytic domains.
    Type: Application
    Filed: May 7, 2013
    Publication date: May 14, 2015
    Inventors: Dorotea Raventos Segura, Peter Fischer Halin, Anders Viksoe-Nielsen, Lars Anderson, Martin Simon Borchert, Leigh Murphy, Astrid Boisen, Lorena G. Palmén, Kenneth Jensen, Carsten Sjoeholm, Tine Hoff, Charlotte Blom
  • Publication number: 20150132833
    Abstract: Stabilized use solutions of low phosphorus, alkali metal carbonate detergents employing enzymes for cleaning compositions are disclosed. In particular, the present invention is a composition for, and method of, removing soils, preventing redeposition of protein soils and reducing foam, using stabilized enzyme cleaning compositions, namely use solutions of the same.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 14, 2015
    Inventors: Wendy Chan, Jennifer Stokes, Lyndal Jensen, Carter M. Silvernail, Terrence P. Everson, Graig Legatt, Nathan Richard Ortmann, Devon Beau Hammel
  • Publication number: 20150125925
    Abstract: The present invention provides consumer products comprising a serine protease variant, more specifically subtilisin variants produced there from. Specifically, the present invention provides consumer products comprising a serine protease variant, more specifically a subtilisin variant having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides methods of making such compositions and methods of treating surfaces, particularly fabric surfaces comprising contacting a surface with an aqueous liquor comprising a serine protease variant, more specifically subtilisin variants and an adjunct material.
    Type: Application
    Filed: November 5, 2013
    Publication date: May 7, 2015
    Applicant: The Procter & Gamble Company
    Inventors: Philip Frank SOUTER, Euan John MAGENNIS, Glenn Steven WARD, Neelam S. AMIN, Katherine AUGUSTYN, Joshua R. BASLER, Luis Gustavo CASCAO-PEREIRA, Katherine D. COLLIER, Edward M. CONCAR, David A. ESTELL, James T. KELLIS, JR., Alexander PISARCHIK, Ayrookaran Joseph POULOSE, Jian YAO
  • Patent number: 9023778
    Abstract: Liquid compositions for cleaning, in particular medical instruments and air conditioning surfaces, said composition excluding surfactants and comprising one or more enzymes including a protease and optionally a hydrolase, a solvent system including a water soluble glycol ether solvent, at least one anionic hydrotrope, and wherein the molar ratio of said at least one hydrotrope to said glycol ether in the composition is selected to preserve the activity of said one or more enzymes. The hydrotrope is advantageously an anionic hydrotrope selected from the group consisting of water soluble anionic hydrotropes of the formula (I) and having no alkyl side chain greater than six carbons in length, for example a xylene sulfonate or cumene sulfonate salt.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: May 5, 2015
    Assignee: Novapharm Research (Australia) Pty Ltd.
    Inventors: Steven Kritzler, Alex Sava
  • Patent number: 9023783
    Abstract: The present application relates to encapsulated, solid, water soluble benefit agents and products comprising such encapsulates, as well as processes for making and using such encapsulates and products comprising such encapsulates. In one aspect, the present application relates to a melamine formaldehyde and/or urea formaldehyde encapsulation process that offers as solution to the dissolution of solid, water soluble benefit agents during the process's emulsification step.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: May 5, 2015
    Assignee: The Procter & Gamble Company
    Inventors: Johan Smets, Susana Fernandez Prieto, Sandra Jacqueline Guinebretiere
  • Publication number: 20150105309
    Abstract: This disclosure relates to powdered automatic dishwashing detergents. More particularly, this disclosure relates to powdered automatic dishwashing detergent packets with superior environmental and human safety as well as superior cleaning efficacy and stability.
    Type: Application
    Filed: October 16, 2014
    Publication date: April 16, 2015
    Applicant: MELALEUCA, INC.
    Inventors: Daniel Smith, Merrill Judy
  • Publication number: 20150104856
    Abstract: A detergent composition comprising a polypeptide having protease activity is disclosed. The composition may be used in laundry or hard surface cleaning such as automated dish wash, and it has improved performance compared with a commercial protease.
    Type: Application
    Filed: May 1, 2013
    Publication date: April 16, 2015
    Inventors: Benie Astrid, Jeppe Wegener Tams, Peter Rahbek Oestergaard, Morten Gjermansen, Martin Simon Borchert
  • Publication number: 20150099284
    Abstract: The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered stability, in particular at high temperatures and/or at low pH relative, and/or low Ca2+ to the parent alpha-amylase.
    Type: Application
    Filed: December 16, 2014
    Publication date: April 9, 2015
    Inventors: Thomas Thisted, Soren Kjaerulff, Carsten Andersen, Claus Crone Fuglsang
  • Patent number: 8999912
    Abstract: This invention relates to laundry detergent compositions comprising bacterial alkaline enzymes exhibiting endo-beta-1,4-glucanase activity (E.C. 3.2.1.4) and fabric hueing agents.
    Type: Grant
    Filed: July 9, 2007
    Date of Patent: April 7, 2015
    Assignee: The Procter & Gamble Company
    Inventor: Neil Joseph Lant
  • Patent number: 8999911
    Abstract: A cleaning composition for treating a surface comprises a purified enzyme and an enzyme denaturant system. The enzyme denaturant system is configured to denature the purified enzyme such that any residue remaining on the surface after the treatment of the surface is virtually free of active purified enzymes.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: April 7, 2015
    Assignee: BISSELL Homecare, Inc.
    Inventors: Kathryn M. Armstrong, Kevin L. Haley, Eric J. Hansen, Joseph A. Fester
  • Publication number: 20150087573
    Abstract: Described are compositions and methods relating to variant alpha-amylasess having altered biochemical properties and advantageous performance characteristics as compared to a reference alpha-amylase. The variants are suitable for use in various industrial applications such as starch conversion, ethanol production, laundry, dishwashing, pulp and paper production, textile desizing, and/or sweetener production.
    Type: Application
    Filed: August 28, 2014
    Publication date: March 26, 2015
    Applicant: Danisco US Inc.
    Inventors: David A. Estell, Brian E. Jones, Marc Kolkman, Christian D. Adams, Edward M. Concar
  • Publication number: 20150082493
    Abstract: The present invention relates to GH61 polypeptide variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: April 26, 2013
    Publication date: March 19, 2015
    Inventors: Janine Lin, Doreen Bohan, Michelle Maranta, Leslie Beresford, Michael Lamsa, Matt Sweeney, Mark Wogulis, Elizabeth Znameroski, Frank Winther Rasmussen
  • Publication number: 20150080283
    Abstract: The present invention relates to variants of a parent ?-amylase, which parent ?-amylase (i) has an amino acid sequence selected from the amino acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, and SEQ ID No.
    Type: Application
    Filed: November 25, 2014
    Publication date: March 19, 2015
    Inventors: Henrik Bisgaard-Frantzen, Allan Svendsen, Torben Vedel Borchert
  • Publication number: 20150072913
    Abstract: The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.
    Type: Application
    Filed: September 11, 2014
    Publication date: March 12, 2015
    Applicant: DANISCO US INC.
    Inventors: Wolfgang Aehle, David A. Estell, Ronaldus W.J. Hommes, Brian E. Jones, Marc Kolkman, Chris Leeflang, Hiroshi Oh, Ayrookaran J. Poulose, Andrew Shaw, Wilhelmus A.H. Van der Kley, Leonardus P.M. Van Marrewijk
  • Publication number: 20150072397
    Abstract: Polynucleotide sequences are provided encoding a thermostable cellulase and directing its increased expression are provided, and the use of the thermostable cellulase in hydraulic fracturing methods and the treatment of flowback fluids.
    Type: Application
    Filed: March 12, 2013
    Publication date: March 12, 2015
    Inventors: Xuqiu Tan, Kenneth E. Barrett, Richard S. Lee
  • Publication number: 20150065412
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Application
    Filed: November 10, 2014
    Publication date: March 5, 2015
    Applicant: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
  • Publication number: 20150064767
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications.
    Type: Application
    Filed: November 10, 2014
    Publication date: March 5, 2015
    Applicant: DANISCO US INC.
    Inventors: Joshua R. Basler, Luis G. Cascao-Pereira, David A. Estell, James T. Kellis
  • Publication number: 20150057213
    Abstract: The present invention relates to compositions comprising water-soluble alkoxylated polyalkyleneimines with a low melting point. More specifically, the present invention relates to compositions comprising water-soluble alkoxylated polyalkyleneimines having an inner polyethylene oxide block comprising 5 to 18 polyethylene oxide units, a middle polyalkylene oxide block comprising 1 to 5 polyalkylene oxide units and an outer polyethylene oxide block comprising 2 to 14 polyethylene oxide units.
    Type: Application
    Filed: July 11, 2014
    Publication date: February 26, 2015
    Inventors: Frank HULSKOTTER, Brian Joseph LOUGHNANE, Sophia Rosa EBERT, Bjoern LUDOLPH
  • Publication number: 20150056682
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications.
    Type: Application
    Filed: November 10, 2014
    Publication date: February 26, 2015
    Applicant: DANISCO US INC.
    Inventors: Viktor Yuryevich Alekseyev, Luis G. Cascao-Pereira, James T. Kellis, JR., Alexander Pisarchik
  • Publication number: 20150056664
    Abstract: The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.
    Type: Application
    Filed: September 3, 2014
    Publication date: February 26, 2015
    Inventors: Sarah Teter, Connie Ward, Joel Cherry, Aubrey Jones, Paul Harris, Jung Yi
  • Publication number: 20150044732
    Abstract: The present invention relates to variants of a parent alpha-amylase, the variant having improved stability or activity at low calcium conditions or at low pH.
    Type: Application
    Filed: October 28, 2014
    Publication date: February 12, 2015
    Inventor: Carsten Andersen
  • Publication number: 20150044736
    Abstract: Described are compositions and methods relating to a fungal cutinase cloned from Magnaporthe grisea, polynucleotides encoding the cutinase, and methods of use thereof. The compositions and methods have particular application in detergent cleaning compositions and synthesis reactions.
    Type: Application
    Filed: July 23, 2014
    Publication date: February 12, 2015
    Applicant: DANISCO US INC.
    Inventors: Christian D. Adams, Andrei Miasnikov
  • Publication number: 20150031600
    Abstract: The present invention relates to designed polypeptide biosurfactants that may be prepared by recombinant technology in commercially useful amounts and purified by simple non-chromatographic methods. The designed polypeptide biosurfactants comprise at least one stimuli-responsive amino acid residue or at least one glutamine or asparagine residue and may be useful in modulating the stability of a foam, alone or in combination with an ?-helical peptide. The designed polypeptide biosurfactant may be useful in the formation and collapse of foams in foods, beverages, pharmaceuticals, personal care products, cosmetics, cleaning products, mineral recovery, bioremediation, oil recovery and laundry products. The designed biosurfactants may also be useful in recombinant production and purification of peptides, polypeptides and proteins.
    Type: Application
    Filed: December 14, 2011
    Publication date: January 29, 2015
    Applicant: The University of Queensland
    Inventors: Anton Peter Jacob Middelberg, Mirjana Dimitrijev-Dwyer, Michael Brech
  • Publication number: 20150031589
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: July 21, 2014
    Publication date: January 29, 2015
    Applicant: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulose, Brian F. Schmidt
  • Publication number: 20150024439
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: September 29, 2014
    Publication date: January 22, 2015
    Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
  • Publication number: 20150023945
    Abstract: The present invention is directed to lysozyme variants and nucleotide sequences encoding same. The lysozyme variants have antimicrobial and/or lysozyme activity and comprise an alteration of an amino acid sequence at one or more positions. The present invention is also directed to methods for producing and of using the Opisthocomus hoazin lysozyme and the lysozyme variants of the present invention as antimicrobial agents.
    Type: Application
    Filed: September 29, 2014
    Publication date: January 22, 2015
    Inventors: Mikkel Klausen, Marie Allesen Holm, Leonardo De Maria, Michael Skjoet
  • Publication number: 20150026843
    Abstract: The present invention relates to isolated polypeptides having proteaseactivity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptidesin e.g. animal feed and detergents.
    Type: Application
    Filed: December 20, 2012
    Publication date: January 22, 2015
    Inventors: Tine Hoff, Carsten Sjoeholm, Peter Rahbek Oestergaard, Katrine Pontoppidan
  • Publication number: 20150017700
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Application
    Filed: December 20, 2012
    Publication date: January 15, 2015
    Inventors: David A. Estell, Thomas P. Graycar, Lene Bojsen Jensen, Anja Hemmingsen Kellett-Smith, Karsten M. Kragh, Rie Mejldal, Sina Pricelius, Jian Yao
  • Patent number: 8927481
    Abstract: In a washing or cleaning agent that contains a solid enzyme formulation, the intention is to improve shelf stability in terms of enzymatic activity. This is achieved by a washing or cleaning agent comprising an enzyme granulate, the granulate comprising, besides the enzyme, the following components: (a) 68 to 90 wt % (w/w) sulfate, in particular alkali metal sulfate, particularly preferably sodium sulfate, (b) 0.1 to 10.5 wt % (w/w) polyethylene glycol, (c) 0.5 to 14.5 wt % (w/w) granulation adjuvant.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: January 6, 2015
    Assignee: Henkel AG & Co. KGaA
    Inventors: Timothy O'Connell, Susanne Tondera, Hendrik Hellmuth, Thomas Weber, Thomas Eiting, Johannes Bongaerts