Enzyme Component Of Specific Activity Or Source (e.g., Protease, Of Bacterial Origin, Etc.) Patents (Class 510/392)
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Publication number: 20120142074Abstract: Disclosed herein are compositions comprising an alpha-amylase enzyme obtained from Bacillus sp. no. 195, and methods of using the enzyme to clean surfaces and textiles. Also disclosed are variants of the enzyme with different signal sequences.Type: ApplicationFiled: December 6, 2011Publication date: June 7, 2012Applicant: Danisco US Inc.Inventors: Neelam S. Amin, Melodie Estabrook, Brian E. Jones, Marc Kolkman, Casper Vroemen, Walter Weyler
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Publication number: 20120141453Abstract: A thermostable glycosidase enzymes derived from various Thermococcus, Staphylothermus and Pyrococcus organisms is disclosed. The enzymes are produced from native or recombinant host cells and can be utilized in the food processing industry, pharmaceutical industry and in the textile industry, detergent industry and in the baking industry.Type: ApplicationFiled: February 15, 2012Publication date: June 7, 2012Applicant: BP Corporation North America Inc.Inventors: Edward J. Bylina, Ronald Swanson, Eric Mathur, David E. Lam
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Patent number: 8193142Abstract: A cleaning composition comprises a dispersion. The dispersion includes an acidic aqueous phase and a suspended particle. The particle is coated with an acid stable coating.Type: GrantFiled: August 31, 2009Date of Patent: June 5, 2012Assignee: Battelle Memorial InstituteInventors: Ramanathan S Lalgudi, Rob J Cain
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Patent number: 8188028Abstract: Surfactant-containing compositions are described which include a protein component that has the effect of improving the surface-active properties of the surfactants contained in the compositions. The surfactant-containing compositions having the protein component demonstrate significantly lower critical micelle concentrations (CMC), reduced surface tensions, and reduced interfacial tensions than do comparable compositions having no protein component. In addition, the surfactant-containing compositions having the protein component has the effect of converting greasy waste contaminants to surface active materials.Type: GrantFiled: January 11, 2010Date of Patent: May 29, 2012Assignee: Advanced BioCatalytics CorporationInventors: John W. Baldridge, Carl W. Podella
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Publication number: 20120128614Abstract: A cleaning composition can comprise aqueous, nonaqueous liquid, or solid formulations The formulations can contain a surfactant and a solvent The solvent has been shown to have utility in promoting removal, solubilizing or cleaning undesirable soil residues from a number of substrates The solvent materials can be used as a component of an aqueous solution, can be combined in a solid or powdered formulation as an encapsulated solvent or can be combined in a solid or powdered formulation as a solvent absorbed on a solid earner The aqueous formulations can be made in the form of a concentrate The cleaner can be combined with water to form an active cleaning solution that can be applied in a variety of cleaning processes The cleaner can contain additional ingredients including surfactants, builders, sequestrates, bleaches, biocides, to be found in cleaners of general and specific applications Personal care cleaning products are also described.Type: ApplicationFiled: May 28, 2010Publication date: May 24, 2012Applicant: SEGETIS, INC.Inventors: Lee R. Rieth, Dorie J. Yontz, Cora M. Leibig, Matthew J. Tjosaas, Benjamin Sean Murrin
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Patent number: 8183024Abstract: The present invention provides a subtilisin variant that is particularly well suited to cleaning applications. In particular, the present invention provides a Bacillus sp. subtilisin variant and cleaning compositions comprising this variant.Type: GrantFiled: November 10, 2009Date of Patent: May 22, 2012Assignee: Danisco US Inc.Inventors: Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, Jr., Ayrookaran J. Poulise
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Publication number: 20120122754Abstract: The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase.Type: ApplicationFiled: January 20, 2012Publication date: May 17, 2012Applicant: NOVOZYMES A/SInventors: Carsten Andersen, Christel Thea Jørgensen, Henrik Bisgård-Frantzen, Allan Svendsen, Søren Kjærulff
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Publication number: 20120122184Abstract: A new strain Bacillus sp. P203 (Bacillus plakortiensis) is disclosed. Isolated mature functional polypeptide which is obtainable from the bacterium strain Bacillus sp. P203 deposited under accession number DSM 17419 are disclosed.Type: ApplicationFiled: January 26, 2012Publication date: May 17, 2012Applicant: NOVOZYMES A/SInventors: Preben Nielsen, Reinhard Wilting, Martin Borchert
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Publication number: 20120107905Abstract: The present invention relates to fungal serine protease variants, which comprise an amino acid substitution of valine at position 208 of the parent Fusarium equiseti Fe_RF6318 serine protease, wherein the position of the substitution corresponds to the amino acid sequence of the mature Fe_RF6318 enzyme defined in SEQ ID NO:2. The variants have improved thermal stability and/or detergent stability compared to the parent Fe_RF6318 enzyme. Preferably the substitution is V208I and more preferably the variants comprise additional amino acid changes which further increase the stability. Also disclosed are nucleic acid sequences encoding said protease variants as well as recombinant vectors and host cells for the production of the variants.Type: ApplicationFiled: October 28, 2011Publication date: May 3, 2012Applicant: AB ENZYMES OYInventors: Kari Juntunen, Leena Valtakari, Nina Hakulinen, Marja Paloheimo
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Publication number: 20120108488Abstract: This invention relates to compositions comprising certain fungal serine proteases and processes for making and using such compositions including the use of such compositions to clean and/or treat a situs.Type: ApplicationFiled: October 21, 2011Publication date: May 3, 2012Inventor: Neil Joseph LANT
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Publication number: 20120107907Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.Type: ApplicationFiled: January 6, 2012Publication date: May 3, 2012Inventors: Andrew Shaw, Louise Wallace, David A. Estell, Ronald W. J. Hommes, Sang-Kyu Lee, Hiroshi Oh, Eugene S. Sadlowski
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Publication number: 20120101019Abstract: The present invention relates to novel JP170 like subtilases from wild-type bacteria, hybrids thereof and to methods of construction and production of these proteases. Further, the present invention relates to use of the claimed subtilases in detergents, such as a laundry or an automatic dishwashing detergent.Type: ApplicationFiled: January 5, 2012Publication date: April 26, 2012Applicant: NOVOZYMES A/SInventors: Preben Nielsen, Poul Erik Pedersen, Helle Outtrup
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Patent number: 8153574Abstract: Fluid detergent compositions comprising an external structurant comprising dibenzylidene polyol acetal derivatives for providing desired rheological benefits such as product thickening, shear thinning behavior, as well as particle suspension capabilities, and a detersive enzyme such as lipase.Type: GrantFiled: March 16, 2010Date of Patent: April 10, 2012Assignee: The Procter & Gamble CompanyInventors: Jean-Pol Boutique, James Charles Theophile Roger Burckett St. Laurent, Myriam Bouilliche, Dennis Allen Beckholt, Sohan Rajpanth Murthy, Mario Elmen Tremblay
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Patent number: 8153412Abstract: Variants of Bacillus sp. TS-23 strain alpha-amylases exhibit improved enzymatic performance, including increased themostability, reduced calcium dependence, increased washing/cleaning performance, and baking ability. Compositions comprising these variants are useful in methods of starch processing, starch liquefaction, fermatation, starch saccharification, cleaning, laundrying, textile desizing, baking, and biofilm removal.Type: GrantFiled: November 3, 2008Date of Patent: April 10, 2012Assignee: Danisco US Inc.Inventors: Claudine Y. Chang, Clement Choy, Melodie Estabrook, Mansi Goyal, Thomas P. Graycar, Victoria E. Huang, Brian E. Jones, Marc Kolkman, Karsten M. Kragh, Chris Leeflang, Scott D. Power, Sandra W. Ramer, Andrew Shaw, Casper Vroemen, Walter Weyler
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Patent number: 8137658Abstract: A liquid, substantially anhydrous tooth whitener composition for delivery of a tooth-whitening amount of active whitening ingredient onto teeth, with effective bioadhesion and retention thereof, and, thereupon, sufficient penetration of the ingredient through the tooth enamel, providing efficacious bleaching of stained teeth.Type: GrantFiled: June 28, 2005Date of Patent: March 20, 2012Assignee: ISP Investments Inc.Inventor: William E. Prosise
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Publication number: 20120058930Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.Type: ApplicationFiled: November 10, 2011Publication date: March 8, 2012Applicants: NOVOZYMES A/S, NOVOZYMES, INC.Inventors: Debbie Yaver, Suzanne Otani, Janine Lin, Christopher Amolo, Kim Borch, Shamkant Anant Patkar, Michael Lamsa, Barbara Cherry
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Publication number: 20120045822Abstract: Described are compositions and methods involving a Bacillus alpha-amylase and a protease. The compositions and methods are especially effective for cold water cleaning applications.Type: ApplicationFiled: April 1, 2010Publication date: February 23, 2012Applicant: DANISCO US INC.Inventors: Edward M. Concar, Christian D. Adams, David A. Estell, Brian E. Jones, Marc Kolkman
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Patent number: 8114656Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.Type: GrantFiled: May 28, 2009Date of Patent: February 14, 2012Assignee: Danisco US Inc.Inventors: Andrew Shaw, Louise Wallace, David A. Estell, Ronaldus W. J. Hommes, Sang-Kyu Lee, Hiroshi Oh, Eugene S. Sadlowski
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Publication number: 20120036599Abstract: This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and methods of use are described. The invention also relates to a method to convert lignocellulosic biomass to fermentable sugars with enzymes that degrade the lignocellulosic material and novel combinations of enzymes, including those that provide a synergistic release of sugars from plant biomass. The invention also relates to methods to use the novel enzymes and compositions of such enzymes in a variety of other processes, including washing of clothing, detergent processes, deinking and biobleaching of paper and pulp, and treatment of waste streams.Type: ApplicationFiled: April 5, 2011Publication date: February 9, 2012Applicant: DYADIC INTERNATIONAL , INC.Inventors: Alexander Vasilievich Gusakov, Peter J. Punt, Jan Cornelis Verdoes, Arkady Panteleimonovich Sinitsyn, Elena Vlasenko, Sandra Wilhelmina Agnes Hinz, Mark Gosink, Zhijie Jiang, Jacoba Van der Meij
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Patent number: 8110539Abstract: A method is disclosed for stabilizing liquid enzyme-containing liquid formulations by adding at least one boron compound and at least one alpha-hydroxy-mono-carboxylic acid or the salt of an alpha-hydroxy-mono-carboxylic acid capable of forming an enzyme-stabilizing compound. An enzyme-stabilized formulation is disclosed comprising an alpha-hydroxy-mono-carboxylic acid or the salt of an alpha-hydroxy-mono-carboxylic acid, a boron containing compound capable complexing with an alpha-hydroxy-mono-carboxylic acid, the complex formed by the boron compound and the an alpha-hydroxy-mono-carboxylic acid, and an enzyme. The invention applies to both enzyme concentrate raw materials, and to useful product formulations.Type: GrantFiled: March 10, 2011Date of Patent: February 7, 2012Assignee: Dow Global Technologies LLCInventor: Pierre Marie Lenoir
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Publication number: 20120030838Abstract: This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and methods of use are described. The invention also relates to a method to convert lignocellulosic biomass to fermentable sugars with enzymes that degrade the lignocellulosic material and novel combinations of enzymes, including those that provide a synergistic release of sugars from plant biomass. The invention also relates to methods to use the novel enzymes and compositions of such enzymes in a variety of other processes, including washing of clothing, detergent processes, deinking and biobleaching of paper and pulp, and treatment of waste streams.Type: ApplicationFiled: April 5, 2011Publication date: February 2, 2012Applicant: DYADIC INTERNATIONAL, INC.Inventors: Alexander Vasilievich Gusakov, Peter J. Punt, Jan Cornelis Verdoes, Arkady Panteleimonovich Sinitsyn, Elena Vlasenko, Sandra Wilhelmina Agnes Hinz, Mark Gosink, Zhijie Jiang, Jacobs Van der Meij
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Publication number: 20120028874Abstract: The present application relates to particles comprising a benefit agent encapsulated by a first layer that is in turn encapsulated by a second material, and products comprising such particles, as well as processes for making and using such particles and products comprising such particles. The process of making such particles does not unduly degrade the benefit agent and when such particles are employed in a product, they are stable, yet they release the desired amount of benefit agent when such product is used as intended.Type: ApplicationFiled: July 20, 2011Publication date: February 2, 2012Inventors: Susana FERNANDEZ PRIETO, Johan Smets, Yousef Georges Aouad, Jean Wevers, Piero Baglioni, Moira Ambrosi, Chiara Vannucci
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Publication number: 20120021489Abstract: Provided in part herein are compositions that include isolated microbial enzymes, such as amylases, lipases, and proteases that are useful as detergent additives. Also provided are methods of isolating amylases, lipases, and proteases from microbes, as well as methods of using these enzymes as detergent additives, and for stain removal.Type: ApplicationFiled: July 24, 2010Publication date: January 26, 2012Inventor: Shaon Ray Chaudhuri
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Publication number: 20120017947Abstract: The present application relates to delivery particles comprising benefit agents, and products comprising such delivery particles, as well as processes for making and using such delivery particles and products comprising such delivery particles. The process of making such particles does not unduly degrade the benefit agent and when such particles are employed in a product, they are stable, yet they release the desired amount of benefit agent when such product is used as intended.Type: ApplicationFiled: July 20, 2011Publication date: January 26, 2012Inventors: Susana FERNANDEZ PRIETO, Alberto Simoncelli, Jose Luis Vega, Johan Smets
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Patent number: 8101562Abstract: Water-soluble detergents and enzymes are used for mechanically cleaning textiles or crockery. According to the invention, enzymes with a catalytic effect on typical stains are added to the washing or cleaning process, only for as long as their catalytic effect is desired. This avoids superfluous removal of the enzymes that have been used in a washing or cleaning process.Type: GrantFiled: March 2, 2007Date of Patent: January 24, 2012Assignee: BSH Bosch und Siemens Hausgeraete GmbHInventor: Egbert Classen
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Publication number: 20120009640Abstract: The present disclosure provides methods useful for producing fatty alcohol compositions from recombinant host cells. The disclosure further provides variant fatty acyl-CoA reductase (FAR) enzymes, polynucleotides encoding the variant FAR enzymes, and vectors and host cells comprising the same.Type: ApplicationFiled: June 28, 2011Publication date: January 12, 2012Applicant: Codexis, Inc.Inventors: Behnaz Behrouzian, Louis Clark, Yihui Zhu, Michael Clay, Kristian Karlshoej
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Publication number: 20120009651Abstract: The present invention provides methods and compositions comprising at least one thermolysin-like neutral protease enzyme with improved storage stability and/or catalytic activity. In some embodiments, the thermolysin finds use in cleaning and other applications comprising detergent. In some particularly preferred embodiments, the present invention provides methods and compositions comprising thermolysin formulated and/or engineered to resist detergent-induced inactivation.Type: ApplicationFiled: October 28, 2008Publication date: January 12, 2012Applicant: DANISCO US INC.Inventors: David A. Estell, Ronaldus W.J. Hommes, Amy D. Liu, Andrew Shaw
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Publication number: 20120003718Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.Type: ApplicationFiled: November 10, 2009Publication date: January 5, 2012Applicant: Danisco US Inc.Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
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Patent number: 8080510Abstract: A detergent composition comprising i) 1-70% of an anionic or nonionic surfactant, ii) 1-75% of a builder, iii) 0.001-5% of at least one compound of Formula (1) wherein R represents a C1-C4alkyl residue and M represents hydrogen or an alkali metal cation, optionally with further FWA's, iv) 0-30% of a peroxide, v) 0-10% of a peroxide activator, vi) 0-5% of a bleaching catalyst and vii) 0-5% of an enzyme, each component by weight, based on the total weight of the detergent composition, use thereof for domestic washing of textile fibre materials and a process for the fluorescent whitening of textile materials.Type: GrantFiled: May 14, 2007Date of Patent: December 20, 2011Assignee: BASF SEInventors: Oliver Becherer, Robert Hochberg, Gerhard Merkle, Bernard Schultz, Purushottam Jugalkishor Chandak
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Publication number: 20110294715Abstract: The present application relates to encapsulated, solid, water soluble benefit agents and products comprising such encapsulates, as well as processes for making and using such encapsulates and products comprising such encapsulates. In one aspect, the present application relates to a melamine formaldehyde and/or urea formaldehyde encapsulation process that offers a solution to the current encapsulation technologies issues.Type: ApplicationFiled: May 26, 2011Publication date: December 1, 2011Inventors: Johan SMETS, Susana Fernandez Prieto, Nianxi Yan
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Publication number: 20110296557Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.Type: ApplicationFiled: December 9, 2009Publication date: December 1, 2011Applicant: Novozymes, Inc.Inventor: Michael Rey
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Publication number: 20110281328Abstract: The present invention provides a Bacillus sp. subtilisin variant. In addition, the present invention provides compositions comprising this serine protease variant. In some embodiments, the present invention provides laundry and other non-automatic (i.e., hand) dishwashing cleaning compositions comprising this serine protease variant.Type: ApplicationFiled: November 10, 2009Publication date: November 17, 2011Applicant: Danisco US Inc.Inventors: David A. Estell, Frits Goedegebuur, Ayrookaran Joseph Poulose
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Publication number: 20110283421Abstract: The present invention relates to isolated polypeptides having amylolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.Type: ApplicationFiled: November 2, 2009Publication date: November 17, 2011Applicant: Novozymes, Inc.Inventors: Paul Harris, Mark Wogulis
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Publication number: 20110277046Abstract: Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. Further provided are polypeptides, e.g., enzymes, having a hydrolase activity, e.g., lipases, saturases, palmitases and/or stearatases and methods for preparing low saturate or low trans fat oils, such as low saturate or low trans fat animal or vegetable oils, e.g., soy or canola oils.Type: ApplicationFiled: August 28, 2009Publication date: November 10, 2011Inventors: Nelson R. Barton, Analia Bueno, Joslin G Cuenca, Tim S. Hitchman, Katie A. Kline, Jonathan D. Lyon, Mark L. Miller, Mark A. Wall, Christopher L.G. Dayton
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Patent number: 8053401Abstract: A detergent and disinfectant in which water-soluble permanganates are used in an alkaline solution in order to initiate the oxidation of organic substances and simultaneously a chemical oxidant, preferably a peroxodisulfate, is used which is capable of producing radical reactions with catalytic support by manganates originating from the supplied permanganate, which reactions produce the oxidation of organic substances. All components are present in powder form and a respective powder mixture can be dissolved rapidly and free from residues in water. It thus represents a universally applicable, highly effective detergent and disinfectant.Type: GrantFiled: December 18, 2009Date of Patent: November 8, 2011Assignee: Thonhauser GmbHInventors: Manfred Thonhauser, Christian Thonhauser
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Publication number: 20110269210Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and that exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions generally comprise at least one of an additional enzyme, a detergent,.a surfactant, a chelator, an oxidizing agent, an acidulant, an alkalizing agent, a source of peroxide, a source of hardness, a salt, a detergent complexing agent, a polymer, a stabilizing agent, or a fabric conditioner. Also disclosed are detergent formulations comprising the variants. Methods of using the compositions for desizing woven material and washing or cleaning items, such as dishes or laundry, are disclosed. Kits related thereto are also provided.Type: ApplicationFiled: June 2, 2011Publication date: November 3, 2011Applicant: Danisco US Inc.Inventor: Mee-Young Yoon
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Patent number: 8048841Abstract: The present invention is a spray mold remover, prepared by filling a bleaching composition in a container having a spraying means, the bleaching composition containing (a) an alkali metal hypochlorite, (b) a cationic surfactant and (c) a compound represented by the formula (1): X1—O(AO)n—X2??(1) wherein, AO represents an alkyleneoxy group having 2 to 4 carbon atoms; n represents an average addition mole number of the alkyleneoxy group ranging from 5 to 150; X1 and X2 each represent a hydrogen atom, —SO3M, —CH2COOM (M represents an alkali metal atom), or an alkyl group having 1 to 6 carbon atoms, with the proviso that X1 and X2 do not represent hydrogen atoms or alkyl groups at the same time.Type: GrantFiled: June 26, 2008Date of Patent: November 1, 2011Assignee: Kao CorporationInventors: Shin Aihara, Yoshiyuki Watanabe, Yosuke Komatsu, Masafumi Shioji
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Publication number: 20110256609Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications.Type: ApplicationFiled: June 3, 2009Publication date: October 20, 2011Inventors: Joshua R. Basler, Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
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Publication number: 20110256610Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications.Type: ApplicationFiled: June 3, 2009Publication date: October 20, 2011Inventors: Viktor Yuryevich Alekseyev, Luis G. Cascao-Pereira, James T. Kellis, JR., Alexander Pisarchik
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Publication number: 20110251116Abstract: The present invention provides novel Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.Type: ApplicationFiled: June 16, 2011Publication date: October 13, 2011Applicant: Danisco US Inc.Inventors: Wolfgang Aehle, David A. Estell, Ronaldus W.J. Hommes, Brian E. Jones, Marc Kolkman, Chris Leeflang, Hiroshi Oh, Ayrookaran J. Poulose, Andrew Shaw, Wilhelmus A.H. Van der Kley, Leonardus P.M. Van Marrewijk
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Publication number: 20110251117Abstract: The present invention relates to a method of constructing a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and at least one altered property as compared to the parent alpha-amylase, comprises i) analyzing the structure of the parent Termamyl-like alpha-amylase to identify at least one amino acid residue or at least one structural part of the Termamyl-like alpha-amylase structure, which amino acid residue or structural part is believed to be of relevance for altering the property of the parent Termamyl-like alpha-amylase (as evaluated on the basis of structural or functional considerations), ii) constructing a Termamyl-like alpha-amylase variant, which as compared to the parent Termamyl-like alpha-amylase, has been modified in the amino acid residue or structural part identified in i) so as to alter the property, and, optionally, iii) testing the resulting Termamyl-like alpha-amylase variant with respect to the property in question.Type: ApplicationFiled: June 16, 2011Publication date: October 13, 2011Applicant: Novozymes A/SInventors: Allan Svendsen, Henrik Bisgard-Frantzen, Torben Vedel Borchert
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Publication number: 20110245134Abstract: The present application relates to encapsulated, solid, water soluble benefit agents and products comprising such encapsulates, as well as processes for making and using such encapsulates and products comprising such encapsulates. In one aspect, the present application relates to a melamine formaldehyde and/or urea formaldehyde encapsulation process that offers as solution to the dissolution of solid, water soluble benefit agents during the process's emulsification step.Type: ApplicationFiled: April 5, 2011Publication date: October 6, 2011Inventors: Johan SMETS, Susana Fernandez Prieto, Sandra Jacqueline Guinebretiere
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Publication number: 20110237487Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.Type: ApplicationFiled: December 9, 2010Publication date: September 29, 2011Inventors: Philip Frank Souter, Glenn Steven Ward, Viktor Yuryevich Alekseyev, Joshua Roy Basler, Luis Gustavo Cascão-Pereira, David A. Estell, Ayrookaran J. Poulose, James T. Kellis, JR., Alexander Pisarchik, Daniel Esteban Torres-Pazmino
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Publication number: 20110230386Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved stability and/or improved wash performance in any detergent in comparison to their wild type parent enzymes. The enzymes are well-suited for use in any detergent and for some in especially liquid or solid shaped detergent compositions.Type: ApplicationFiled: May 25, 2011Publication date: September 22, 2011Applicants: Novozymes A/S, Unilever PLCInventors: Laurens Nicolaas Sierkstra, Jan Klugkist, Peter Markvardsen, Claus Von der Osten, Peter Bauditz
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Publication number: 20110229956Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.Type: ApplicationFiled: May 13, 2011Publication date: September 22, 2011Applicants: Danisco US Inc., Genencor International, Inc.Inventors: Anthony Day, Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe, Mats Sandgren, Andrew Shaw, Jerry Stahlberg
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Publication number: 20110230384Abstract: Detergents and cleaning agents containing a protease having an amino acid sequence being at least 97.5% identical to the amino acid sequence given in SEQ ID NO. 3. The detergents and cleaning agents exhibit an excellent cleaning action on protease-sensitive soiling.Type: ApplicationFiled: May 27, 2011Publication date: September 22, 2011Inventors: Petra Siegert, Astrid Spitz, Karl-Heinz Maurer
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Patent number: 8022027Abstract: The present invention relates to a composition comprising: (i) a lipase; and (ii) a bleach catalyst that is capable of accepting an oxygen atom from a peroxyacid and transferring the oxygen atom to an oxidizeable substrate.Type: GrantFiled: January 22, 2007Date of Patent: September 20, 2011Assignee: The Procter & Gamble CompanyInventors: Philip Frank Souter, Neil Joseph Lant, Alan Thomas Brooker, Gregory Scot Miracle, Nicola Jane Binney, David Lee Daugherty
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Publication number: 20110224123Abstract: The present invention relates to isolated polypeptides having lipase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.Type: ApplicationFiled: May 24, 2011Publication date: September 15, 2011Applicants: Novozymes, Inc., Novozymes A/SInventors: Debbie Yaver, Suzanne Otani, Janine Lin, Chritopher Amolo, Kim Borch, Shamkant Anant, Michael Lamsa, Barbara Cherry
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Patent number: 8012267Abstract: A method of machine cleaning dishes in a dishwasher, wherein over the course of a cleaning program, having a pre-rinsing operation and a cleaning operation, two liquid cleansers A and B having the following composition: A:—10 to 75 wt % of builder(s); ?0.1 to 10 wt % of enzyme(s); ?24.9 to 89.9 wt % of solvent; and B: ?10 to 74.9 wt % of builder(s); ?25 to 89.9 wt % of solvent; are metered into the wash bath at two successive times t1 and t2. The liquid cleanser A has a pH value (20° C.) of between 6 and 9 and is metered in at time t1, while the liquid cleanser B has a pH value (20° C.) of between 9 and 14 and is metered in at time t2.Type: GrantFiled: December 19, 2008Date of Patent: September 6, 2011Assignee: Henkel AG & Co. KGaAInventors: Maren Jekel, Johannes Zipfel, Arnd Kessler
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Publication number: 20110212876Abstract: The present invention relates to cleaning compositions comprising variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme and cleaning processes comprising such compositions.Type: ApplicationFiled: February 10, 2011Publication date: September 1, 2011Inventors: Michelle MEEK, Philip Frank Souter, Lindsay Suzanne Bewick, Allan Svendsen, Annette Helle Johansen, Mads Eskelund Bjoernvad, Frank Winther Rasmussen, Michael Skjoet, Signe Eskildsen Larsen, Jens Oebro, Svend Kaasgaard, Lars Beier