Enzyme Composition Patents (Class 510/530)
  • Patent number: 5866407
    Abstract: A method, and a specific enzyme mixture, for depilling cotton-containing goods, either as unfinished fabric or as finished garments, to create a smooth surface while minimizing the loss of fabric strength. The method consists essentially of removing less than approximately 3.0% of the initial fabric weight with a Trichoderma cellulase enzyme mixture comprising less than naturally-occuring amounts of CBHI, CBHII, EGI and EGIII protein components, and further consisting essentially of at least 80% endoglucanase II (EGII) as the protein component.
    Type: Grant
    Filed: March 18, 1997
    Date of Patent: February 2, 1999
    Assignee: Iogen Corporation
    Inventors: Brian Foody, Jeffrey S. Tolan
  • Patent number: 5866526
    Abstract: An enzyme preparation comprising a modified enzyme selected from the group consisting of an amylase, lipase, oxidorcductase, pectinace or hemicellulase, the modified enzyme having an improved performance due to an alkaline pI and/or increased surface activity obtained by chemical modification or amino acid substitution, is useful e.g., in detergents, in baking flour, in animal feed, in the manufacture of cellulosic fabrics and for the treatment of lignocellulosic fibers.
    Type: Grant
    Filed: May 2, 1996
    Date of Patent: February 2, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Arne Agerlin Olsen, Allan Svendsen, Kim Borch, Henrik Lund, Marianne Thellersen, Peter Rosholm, Niels Munk
  • Patent number: 5858948
    Abstract: Liquid laundry detergent compositions comprising water soluble and/or dispersible, modified polyamines having functionalized backbone moieties which provide cotton soil release benefits (optionally in combination with non-cotton soil release agents) and protease enzymes.
    Type: Grant
    Filed: April 22, 1997
    Date of Patent: January 12, 1999
    Assignee: Procter & Gamble Company
    Inventors: Chanchal Kumar Ghosh, Sanjeev Krishnadas Manohar, Eugene Paul Gosselink, Randall Alan Watson
  • Patent number: 5858299
    Abstract: A bed of particulate solids including some hydrated materials can be converted by controlled irradiation with subinfrared electromagnetic radiation into a unitary porous solid that is mechanically strong enough for easy handling. When the particulate solids include typical acid to alkaline cleaner materials, a block or tablet especially suitable for automatic cleaning machinery, with a very fast dissolution rate in water, can readily be obtained.
    Type: Grant
    Filed: February 7, 1997
    Date of Patent: January 12, 1999
    Assignee: Ecolab, Inc.
    Inventors: Peter J. Fernholz, Sandra Witt, Hans-Peter Koehler, Wolfgang Preibsch, Horst Pruehs, Karl-Heinz Rogmann
  • Patent number: 5858952
    Abstract: The present invention provides an enzyme-containing granulated product containing, in a uniformly dispersed state, an enzyme and one or more stabilizers selected from the group consisting of reducing agents and antioxidants. The invention also discloses a method for the production of the granulated product, as well as bleaching agents and detergent compositions containing the granulated product. The granulated product loses only a minimal level of enzyme activity even in the copresence of a bleaching agent, and exhibits excellent solubility. Therefore, bleach compositions and detergent compositions prepared by incorporating the granulated product fully exhibit the enzyme activity and bleaching activity.
    Type: Grant
    Filed: November 27, 1996
    Date of Patent: January 12, 1999
    Assignee: Kao Corporation
    Inventors: Yoshifumi Izawa, Takaaki Watanabe, Nobuharu Kotani
  • Patent number: 5855621
    Abstract: The transfer of a textile dye from a dyed fabric to another fabric during washing or rinsing is inhibited by adding an enzyme exhibiting peroxidase activity or an enzyme exhibiting a suitable oxidase activity to the wash liquor in which said fabrics are washed and/or rinsed. Peroxidase is produced extracellularly by some strains of Bacillus pumilus. The novel peroxidase preparation from B. pumilus is a microperoxidase, i.e. it contains hemopeptide as an active component. The preparation has improved stability at high temperature, at high pH and at high concentrations of hydrogen peroxide. It can be produced without undesired catalase activity.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: January 5, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Ture Damhus, Ole Kirk, Gitte Pedersen, Manuel Garcia Venegas
  • Patent number: 5855625
    Abstract: A laundry detergent for washing fabrics composed of proteinogenic fibers is comprised of at least one surfactant and a proteolytically active amount of a protease having a keratinase/caseinase activity ratio of less than about 0.80.
    Type: Grant
    Filed: August 14, 1997
    Date of Patent: January 5, 1999
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Karl-Heinz Maurer, Winfried Pochandke, Beatrix Kottwitz, Jorg Poethkow, Albrecht Weiss, Irmgard Schmidt, Horst Upadek
  • Patent number: 5851973
    Abstract: This invention is a manual dishwashing composition which comprises surfactant, calcium or magnesium ions, amylase enzymes, lipase enzymes, and polycarboyxlic polymer thickeners. An additional agent includes a calcium stabilizing agent such as malic acid or malic acid salt, maleic acid or maleic acid salt.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: December 22, 1998
    Assignee: The Procter & Gamble Company
    Inventor: Peter Robert Foley
  • Patent number: 5851975
    Abstract: The present invention relates to an enzyme-containing granulated substance comprising an enzyme-containing particulate substance and a coating layer which is formed on the particulate substance and comprises (a) water-insoluble or hardly water-soluble inorganic particles having an average particle diameter of 1 to 100 .mu.m, (b) water-insoluble or hardly water-soluble inorganic particles having an average particle diameter of 0.01 to 0.8 .mu.m and (c) a binder, and a preparation process thereof. The enzyme-containing granulated substance is not only high in productivity but also low in dusting characteristics and high in storage stability, and is hence useful as a formulation ingredient for detergents, in particular, bleacher-containing detergents.
    Type: Grant
    Filed: January 28, 1997
    Date of Patent: December 22, 1998
    Assignee: Kao Corporation
    Inventors: Toshihiro Kiuchi, Kohtaro Sano, Manabu Sato, Jyo Kawamura, Naoto Yamada
  • Patent number: 5846927
    Abstract: The present invention relates to improved matrix or core shell enzyme capsule compositions comprising certain density modifying solids and defined core structural ingredients. Using these capsule compositions, much better active stability is obtained. In addition, higher active retention is accomplished during capsule formation. Release characteristics are not compromised. In a second embodiment of the invention, the invention relates to structured heavy duty liquid compositions comprising these capsules.
    Type: Grant
    Filed: April 8, 1996
    Date of Patent: December 8, 1998
    Assignee: Lever Brothers Company, Division of Conopco, Inc.
    Inventor: Tirucherai Varahan Vasudevan
  • Patent number: 5840678
    Abstract: Aqueous liquid detergent compositions are described which comprise a proteolytic enzyme wherein the proteolytic activity is reversibly inhibited by a peptide trifluoromethyl ketone.
    Type: Grant
    Filed: September 25, 1996
    Date of Patent: November 24, 1998
    Assignee: Procter & Gamble Company
    Inventors: Regine Labeque, John McMillan McIver, Christiaan Arthur J.K. Thoen
  • Patent number: 5840677
    Abstract: The invention relates to a detergent composition comprising an enzyme and a boronic acid or borinic acid derivative which acts as a stabilizer for the enzyme in detergent compositions. Specific boronic acid inhibiters include benzofuran substituted boronic acids.
    Type: Grant
    Filed: January 25, 1996
    Date of Patent: November 24, 1998
    Assignees: Novo Nordisk A/S, Borax Consolidated Ltd.
    Inventors: Lone Kierstein Nielsen, Allison Deane-Wray
  • Patent number: 5837010
    Abstract: The invention concerns detergent compositions comprising lipase variant D96L of the native lipase derived from Humicola lanuginosa present at a level of from 50 LU to 8500 LU per liter wash solution.Using these levels of lipase delivers an improved whiteness maintenance on fabrics.
    Type: Grant
    Filed: October 11, 1996
    Date of Patent: November 17, 1998
    Assignee: Procter & Gamble Company
    Inventors: Andre Baeck, Chandrika Kasturi
  • Patent number: 5834415
    Abstract: A liquid detergent composition comprising a surfactant, an enzyme and a naphthalene boronic acid derivative enzyme stabilizer.
    Type: Grant
    Filed: October 21, 1996
    Date of Patent: November 10, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Lone Kierstein Nielsen, Allison Deane-Wray
  • Patent number: 5830840
    Abstract: The invention relates to a detergent composition which is a liquid detergent composition which comprises a surfactant, a proteolytic enzyme, and an enzyme inhibitor which is a peptide aldehyde. Said peptide aldehyde inhibitor contain 4 or 5 amino acids. Said peptide aldehydes are used to enhance the stability of proteolytic enzymes in liquid detergent environments.
    Type: Grant
    Filed: September 25, 1996
    Date of Patent: November 3, 1998
    Assignee: The Procter & Gamble Company
    Inventors: James Pyott Johnston, Regine Labeque, Pierre Marie Alain Lenoir, Christiaan Arthur J. K. Thoen, John McMillan McIver
  • Patent number: 5820696
    Abstract: A method of simultaneously cleaning and disinfecting a contact lens is disclosed, which method comprises the steps of: (a) preparing a cleaning solution for the contact lens comprising an effective amount of a proteolytic enzyme, 15-60 w/v % (percent by weight/volume) of propylene glycol, 10-60 w/v % of glycerine, and water, a total content of the propylene glycol and glycerine being in a range of 30-80 w/v %; (b) diluting the cleaning solution with a disinfecting or storing liquid for the contact lens which contains an ionic antimicrobial agent, so as to provide a dilution; and (c) immersing the contact lens in the dilution.
    Type: Grant
    Filed: July 31, 1996
    Date of Patent: October 13, 1998
    Assignee: Tomey Technology Corporation
    Inventors: Norio Kimura, Akira Nakagawa, Hiroyasu Satoh
  • Patent number: 5821215
    Abstract: Compositions including one or more enzymes and as the compatible chelating surfactant, salts of N-acyl ethylenediaminetriacetic acid ("ED3A"). Salts of N-acyl ED3A do not readily denature various enzymes, and thus are highly compatible with such enzymes, and enhance their detergent effectiveness to an unexpected degree.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: October 13, 1998
    Assignee: Hampshire Chemical Corp.
    Inventors: Joseph J. Crudden, Joseph Lazzaro, Brian A. Parker
  • Patent number: 5814501
    Abstract: Substantially dust-free enzyme-containing particles are prepared by spray-coating solid particulate cores with a fermentation broth containing enzymes. Fermentation broths containing from 5% to 100% total enzyme solids and 4%-55% total solids content in the broth may be used. For broths containing 4%-31% total solids, enzyme and coating agents may be spray-coated so as to achieve a weight gain of 1%-24% w/w over the initial weight of the cores. For broths with 31%-55% total solids, a corresponding weight gain of 1%-100% may be achieved. The enzyme coated cores may be further coated with coating agents. The total dry weight added to the cores ranges from 1% to 19% in the absence of coating agents and 1% to 24% in the presence of coating agents when the lower range of total solids content is used. The total dry weight added to the cores ranges from 1% to 100% when the higher range of total solids content is used.
    Type: Grant
    Filed: February 15, 1995
    Date of Patent: September 29, 1998
    Assignee: Genencor International, Inc.
    Inventors: Nathaniel T. Becker, Richard P. Crowley
  • Patent number: 5811382
    Abstract: The invention relates to a detergent additive and a detergent composition which comprises a protease enzyme derived from Nocardiopsis, a surfactant, and either/or an enzyme which exhibits peroxidase activity and hydrogen peroxide or precursor thereof or an oxidase enzyme which acts on an aromatic compound.
    Type: Grant
    Filed: April 24, 1994
    Date of Patent: September 22, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Ture Damhus, Egon Nielsen, Dorrit Anita Aaslyng
  • Patent number: 5803986
    Abstract: There is provided a detergent composition comprising detergent components characterized in that it contains polygalacturanase enzymes substantially free of other pectic enzyme. The polygalacturanase enzyme is preferably incorporated into the compositions at a level of from 0.0001% to 2% active enzyme by weight of the composition.
    Type: Grant
    Filed: March 17, 1997
    Date of Patent: September 8, 1998
    Assignee: The Procter & Gamble Company
    Inventors: Andre Baeck, Linda Anne Jones, Chandrika Kasturi, Michael Stanford Showell, Ann Margaret Wolff
  • Patent number: 5801140
    Abstract: A process for the production of stable fluid enzyme dispersions having a content of at least 0.5% by weight enzyme, in which the enzyme is present in the form of anhydrous particles of a diameter less than 30 .mu.m, comprising emulsifying an enzyme composition into a water immiscible liquid in the presence of a polymeric dispersion stabilizer to form a stable dispersion of aqueous enzyme particles having a dry size below 30 .mu.m dispersed in the liquid, and dehydrating the dispersed particles by azeotropic distillation, wherein before, during or after dehydrating the particles the process comprises adding an organic liquid which is less volatile than the water immiscible liquid and which is selected from surfactants and water miscible liquids to the dispersion and distilling the water immiscible liquid from the dispersion until the amount of the initial water immiscible liquid remaining in the dispersion is below 20% by weight of the liquid phase in the dispersion.
    Type: Grant
    Filed: February 7, 1996
    Date of Patent: September 1, 1998
    Assignee: Allied Colloids Limited
    Inventors: John Graham Langley, Kenneth Charles Symes, Kishor Kumar Mistry
  • Patent number: 5798327
    Abstract: There is provided an enzymatic detergent composition comprising a surfactant and an endoglucanase producible from Thermomonospora fusca, preferably E5, or mutants or variants thereof.
    Type: Grant
    Filed: November 20, 1996
    Date of Patent: August 25, 1998
    Assignee: Lever Brothers Company
    Inventors: Eric Casteleijn, Willem R. van Dijk, Jan Klugkist, Pieter Dirk van Wassenaar
  • Patent number: 5792736
    Abstract: The invention discloses stabilized enzymes suitable for use in a contact lens cleansing composition. Specific stabilizers for the protease enzyme include sodium lauroyl sarcosinate, lauroyl-L-glutamic triethanolamine, sodium myristyl sarcosinate, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, hydrochloric alkyldiaminoglycine, polyoxyethylene sorbitan monooleate, polyoxyethylene castor oil 60, polyoxyl 40 stearate, and polyoxyethylene lauryl ether. The invention further discloses that the enzyme and surfactant mixture are lyophilized.
    Type: Grant
    Filed: November 3, 1997
    Date of Patent: August 11, 1998
    Assignee: Senju Pharmaceutical Co., Ltd.
    Inventors: Hisayuki Nakayama, Akihiro Kimoto, Kuniko Tsuchino
  • Patent number: 5789364
    Abstract: The invention provides a high water liquid enzyme prewash composition essentially free of hydrotropes, solvents, dispersants and surfactants, other than nonionic surfactants, combining: a hydrolase enzyme stabilized with a first enzyme stabilizer, wherein the first enzyme stabilizer is a soluble alkaline earth salt; a more hydrophilic, first nonionic surfactant having an HLB of greater than about 11; a more hydrophobic, second nonionic surfactant having an HLB of less than or equal to about 11; and at least about 80-99% water; wherein the difference in HLB between the first and the second nonionic surfactants is at least 2; the nonionic surfactants interact with the water to form an opalescent, structured liquid; the first and the second nonionic surfactants are selected from the group consisting of alkoxylated alcohols and alkoxylated alkylphenols; the structured liquid both suspends the hydrolase and protects the hydrolase against deactivation with water.
    Type: Grant
    Filed: June 13, 1996
    Date of Patent: August 4, 1998
    Assignee: The Clorox Company
    Inventors: Todd Douglas Sells, David Lawrence DeLeeuw, Michael Koerner
  • Patent number: 5786316
    Abstract: The invention concerns compositions comprising xylanolytic activity. Specfically, the invention relates to detergent compositions havin xylanase activity. Specific compositions show an excellent boost on cleaning performanc on fruit, vegetables and/or mud and clay compounds containing said soil.
    Type: Grant
    Filed: April 16, 1997
    Date of Patent: July 28, 1998
    Assignee: The Procter & Gamble Company
    Inventors: Andre Cesar Baeck, Alfred Busch, Ann Katrien Marie Agnes Verschuere
  • Patent number: 5785767
    Abstract: It is an object of the present invention to provide a cleaning and disinfecting solution for a contact lens to be cleaned and disinfected simultaneously in a simplified manner with high efficiency. It is also an object of the present invention to provide a method of cleaning and disinfecting the contact lens wherein the cleaning and disinfection of the contact lens can be effected simultaneously in a short period of time by using the above-indicated cleaning and disinfecting solution. The above objects may be obtained according to one aspect of the present invention which provided a cleaning and disinfecting solution for a contact lens comprising an effective amount of proteolytic enzyme, 60-80% w/v % of propylene glycol, 10-35% w/v % of glycerine, and water, a total content of propylene glycol and glycerine being in the range of 70% to 95 w/v %.
    Type: Grant
    Filed: October 3, 1996
    Date of Patent: July 28, 1998
    Assignee: Tomey Technology Corporation
    Inventors: Norio Kimura, Akira Nakagawa
  • Patent number: 5782932
    Abstract: Enzymatic compositions with improved storage stability of the enzymes contained therein are obtained by including an enzyme stabiliser, preferably by way of a particular process.
    Type: Grant
    Filed: June 18, 1996
    Date of Patent: July 21, 1998
    Assignee: Lever Brothers Company, Division of Conopco, Inc.
    Inventors: Willem Robert van Dijk, Marja Ouwendijk, Peter John Hall
  • Patent number: 5783546
    Abstract: A detergent composition comprising an amylase enzyme which shows CMCase activity and/or is an amylase showing a positive immunological cross reaction with the antibody of the Fungamyl amylase, or an amylase produced by a host organism in which the gene encoding the Fungamyl has been cloned.
    Type: Grant
    Filed: October 18, 1996
    Date of Patent: July 21, 1998
    Assignee: Procter & Gamble Company
    Inventors: Jean-Luc Philippe Bettiol, Michael Alan John Moss, Christiaan Arthur Jacques Kamiel Thoen, Stanton Lane Boyer, Michael Stanford Showell, Janice Jeffrey
  • Patent number: 5783532
    Abstract: Enzyme compositions and methods employing enzyme compositions are disclosed which are useful for cleaning contact lenses. In one embodiment, a composition in accordance with the present invention comprises an enzyme component effective when released in a liquid medium to remove debris from a contact lens located in the liquid medium; and an activity regulating component effective when released in the liquid medium to deactivate the enzyme component located in the liquid medium. This composition is preferably structured so that the enzyme component is released in the liquid medium before the activity regulating component is so released. The period of time between the release of the enzyme component and the activity regulating component is sufficient to allow the enzyme component to effectively remove debris from a contact lens which is introduced into the liquid medium before or at the same time the enzyme component is released in the liquid medium.
    Type: Grant
    Filed: August 14, 1996
    Date of Patent: July 21, 1998
    Assignee: Allergan
    Inventor: Stanley W. Huth
  • Patent number: 5783547
    Abstract: The present invention is concerned with granular components comprising an enzyme, specified polymeric binding material, and a mixture of coating components. The granular components are particularly suitable for use in detergent compositions.
    Type: Grant
    Filed: September 24, 1996
    Date of Patent: July 21, 1998
    Assignee: The Procter & Gamble Company
    Inventor: Carole Patricia Denise Wilkinson
  • Patent number: 5780422
    Abstract: Bacteria which produce large amounts of a cellulase-containing cell-free fermentate have been identified. The original bacterium (ATCC 55703) was genetically altered using nitrosoguanidine (MNNG) treatment to produce the enhanced cellulase producing bacterium (ATCC 55702), which was identified through replicate plating. ATCC 55702 has improved characteristics and qualities for the degradation of cellulosic waste materials for fuel production, food processing, textile processing, and other industrial applications. ATCC 55702 is an improved bacterial host for genetic manipulations using recombinant DNA techniques, and is less likely to destroy genetic manipulations using standard mutagenesis techniques.
    Type: Grant
    Filed: October 8, 1996
    Date of Patent: July 14, 1998
    Assignee: Lockheed Martin Energy Systems, Inc.
    Inventor: H. Craig Dees
  • Patent number: 5780283
    Abstract: A method for stabilizing an enzyme against decomposition at elevated temperatures or by water is described which comprises combining the enzyme with stabilizing amounts of a non-ionic polyether-polyol block-copolymer surfactant. Stabilized compositions based on the enzyme and surfactant are also described.
    Type: Grant
    Filed: September 15, 1995
    Date of Patent: July 14, 1998
    Assignee: Buckman Laboratories International, Inc.
    Inventor: James C. Lee
  • Patent number: 5763383
    Abstract: A highly alkaline, positionally non-specific lipase can be obtained from the strains of streptomyces, cluster 1. Strains of cluster 1 of Streptomyces were not previously known to produce lipase. The lipase preparation has more than 50% of its optimum activity at pH 10 and is useful, e.g. in detergents.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: June 9, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Miyoko Hashida, Naoko Ikegami, Masanobu Abo, Yukiko Takamura
  • Patent number: 5759984
    Abstract: Methods for stabilizing enzymes in liquid compositions, including those liquid compositions having a high water content and those stabilized enzyme liquid compositions formed thereby. The method involves forming the enzyme, so that it is in an insoluble form thereof and then adding thereto an agent for maintaining the enzyme in the insoluble form thereof. Examples of such insoluble forms are crystal forms of the enzyme. Enzymes which are stabilized in this manner are useful for combining with liquid compositions, including liquid compositions having a high water content. The method is particularly useful for the preparation of stable enzyme-containing liquid detergent compositions.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: June 2, 1998
    Inventors: Jayarama K. Shetty, Chimanbhai P. Patel
  • Patent number: 5736499
    Abstract: Novel .alpha.-amylase enzymes are disclosed in which one or more asparagine residues are substituted with a different amino acid or deleted. The disclosed .alpha.-amylase enzymes show altered or improved low pH starch hydrolysis performance, stability and activity profiles.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 7, 1998
    Assignee: Genencor International, Inc.
    Inventors: Colin Mitchinson, Carol Ann Requadt, Traci Helen Ropp, Leif P. Solheim
  • Patent number: 5733763
    Abstract: An enzyme-containing granulate is prepared containing a core and a shell wherein the core and/or shell contain an enzyme and the shell contains artificial or cellulose fibers in an amount of 1.5-40%. The core may also contain the fibers in an amount of 1.5-40%. In a preferred embodiment, the core contains a primary enzyme, the fibers, a coating of a sustained release agent, and the shell contains a secondary enzyme and the fibers. The sustained release coating causes the primary enzyme to be released more slowly than the secondary enzyme in a washing solution. In another embodiment, the core contains a primary detergent additive, a coating of a protective agent, and the shell contains a secondary detergent additive and the fibers. The protective coating separates the primary and secondary detergent additives so they do not harm each other during storage. Preferably, the core and shell also contain a binder, a filler and a granulating agent.
    Type: Grant
    Filed: May 1, 1996
    Date of Patent: March 31, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Erik Kj.ae butted.r Markussen, Per Falholt
  • Patent number: 5731280
    Abstract: The present invention relates to lipase and .alpha.-amylase variants, stabilized towards the inactiviation caused by peroxidase systems, in which variants a naturally occurring tryosine residue has been deleted, substituted with a different amino acid residue at one or more positions. The invention also relates to a method of stabilizing a lipase or an .alpha.-amylase towards the inactivation caused by the preoxidase systems, and detergent compositions comprising a lipase and/or .alpha.-amylase variant of the invention.
    Type: Grant
    Filed: June 15, 1995
    Date of Patent: March 24, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Egon Nielsen, Grethe Rasmussen, Torben Halkier
  • Patent number: 5723421
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: October 18, 1995
    Date of Patent: March 3, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood A. Chowhan, Ronald P. Quintana, Bahram Asgharian, Bor-Shyue Hong, Thierry Bilbault, Ruth Ann Rosenthal
  • Patent number: 5721205
    Abstract: Fabric softening compositions comprising fabric softening active(s), cellulase and an antioxidant effective amount of free radical scavenging antioxidant material and/or chelant.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: February 24, 1998
    Assignee: The Procter & Gamble Company
    Inventors: Mary Vijayarani Barnabas, Kimberley Suzanne Severin, Scott William Waite
  • Patent number: 5719115
    Abstract: Enzyme granules containing an enzyme, an inorganic or organic carrier material and a uniform outer pigment-containing coating layer on the granules, wherein the outer coating layer contains 30 to 50% by weight of fine-particle inorganic pigment, 45 to 60% by weight of an alcohol or alcohol mixture having a melting point of from 45.degree. C. to 65.degree. C., up to 15% by weight of an emulsifier for the alcohol or alcohol mixture, up to 5% by weight of a dispersant for the pigment and up to 3% by weight of water, based on the weight of the outer coating layer.
    Type: Grant
    Filed: March 5, 1996
    Date of Patent: February 17, 1998
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Kathleen Paatz, Wilfried Raehse, Werner Pichler, Norbert Kuehne, Horst Upadek
  • Patent number: 5707950
    Abstract: The invention concerns laundry detergent compositions comprising lipase (especially the variant D96L of the native lipase derived from Humicola lanuginosa), protease, and surfactant, wherein said compositions comprise levels of lipase enzyme and protease enzyme such that the whitening performance of said compositions is increased. These compositions deliver an improved whiteness maintenance and/or dingy clean-up on fabrics.
    Type: Grant
    Filed: October 11, 1996
    Date of Patent: January 13, 1998
    Assignee: The Procter & Gamble Company
    Inventors: Chandrika Kasturi, Andre Baeck, Ann Margaret Wolff
  • Patent number: 5705469
    Abstract: A process is disclosed for the manufacture of a liquid detergent composition comprising a sulphiting agent and an enzyme system. Said enzyme system and said sulphiting agent interact together so as to generate odors which result in an odor deviation in said detergent composition. In the process of the invention, said enzyme system and said sulphiting agent are intimately mixed together separately from the remainder of the detergent composition so as to generate said odors outside the remainder of said detergent composition. Also disclosed is an enzyme premix consisting essentially of said enzyme system and said sulphiting agent.
    Type: Grant
    Filed: April 20, 1995
    Date of Patent: January 6, 1998
    Assignee: The Procter & Gamble Company
    Inventors: Alan David Blake, Jozef Philemona R. Geudens, Paul Andrew Hardy, Fabrice Francois J. Questel
  • Patent number: 5703032
    Abstract: The present invention relates to a specific ternary enzyme stabilization system which unexpectedly enhances stability of a specific cellulase enzyme in isotropic liquid detergent compositions.
    Type: Grant
    Filed: March 6, 1996
    Date of Patent: December 30, 1997
    Assignee: Lever Brothers Company, Division of Conopco, Inc.
    Inventors: Myongsuk Bae-Lee, Nancy Falk, Tirucherai Varahan Vasudevan
  • Patent number: 5700770
    Abstract: The transfer of a textile dye from a dyed fabric to another fabric during washing or rinsing is inhibited by adding an enzyme exhibiting peroxidase activity or an enzyme exhibiting a suitable oxidase activity to the wash liquor in which said fabrics are washed and/or rinsed. Peroxidase is produced extracellularly by some strains of Bacillus pumilus. The novel peroxidase preparation from B. pumilus is a microperoxidase, i.e. it contains hemopeptide as an active component. The preparation has improved stability at high temperature, at high pH and at high concentrations of hydrogen peroxide. It can be produced without undesired catalase activity.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: December 23, 1997
    Assignee: Novo Nordisk A/S
    Inventors: Ture Damhus, Ole Kirk, Gitte Pedersen, Manuel Garcia Venegas
  • Patent number: 5700769
    Abstract: This invention relates to activation of enzymes. More specifically, the invention relates to peroxidase enhancing agents. The invention also relates to methods of oxidizing a substrate with a source of hydrogen peroxide in the presence of a peroxidase enzyme and a peroxidase enhancing agent More specifically, the invention relates to a method of bleaching of dye in solutions, to a method of inhibiting the transfer of a textile dye from a dyed fabric to another fabric when said fabrics are washed together in a wash liquor, to a method of bleaching of lignin-containing material in particular bleaching of pulp for paper production, to a method of treatment of waste water from pulp manufacturing, and to a method of enzymatic polymerization and/or modification of lignin or lignin containing material.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: December 23, 1997
    Assignee: Novo Nordisk A/S
    Inventors: Palle Schneider, Lars Sparre Conrad, S.o slashed.ren Ebdrup, Birgitte Yde
  • Patent number: 5696068
    Abstract: The present invention relates to novel microorganisms, novel enzymes obtainable herefrom, and to a method of producing the novel enzymes. More specifically, the invention relates to novel enzymes obtainable from strains of the novel alkalophilic species Bacillus sp. AC13. Moreover, the invention relates to a method for producing the enzymes of the invention, and to the use of the enzymes in detergents or in the paper pulp industry.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 9, 1997
    Assignee: Novo Nordisk A/S
    Inventors: Helle Outtrup, Claus Dambmann, Arne Agerlin Olsen, Henrik Bisg.ang.rd-Frantzen, Martin Schulein
  • Patent number: 5693602
    Abstract: A phosphate-free powdered dishwashing composition containing a mixture of a protease enzyme and an amylase enzymes have been found to be very useful in the cleaning of dishware. The compositions contain nonionic surfactants and a alkali metal silicate and bleaching agent.
    Type: Grant
    Filed: November 9, 1993
    Date of Patent: December 2, 1997
    Assignee: Colgate-Palmolive Co.
    Inventors: Julien Draiper, Fahim U. Ahmed, Patrick Durbut
  • Patent number: 5691178
    Abstract: A cellulase preparation useful for reducing the harshness of cotton-containing fabrics and for reducing the rate at which such fabrics become harsh comprises about 40% or more (based on the total protein content) of an endoglucanase component with a pH optimum of about 7.5-10.0 with a high CMC-endoase activity and affinity towards cellulose and essentially no cellobiohydrolase activity. The cellulase composition is endogenous to a strain of Humicola, Myceliophthora, or Fusarium.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 25, 1997
    Assignee: Novo Nordisk A/S
    Inventors: Martin Schulein, Kirsten B.o slashed.egh Levring
  • Patent number: 5691295
    Abstract: A laundry detergent for washing fabrics composed of proteinogenic fibers is comprised of at least one surfactant and a proteolytically active amount of a protease having a keratinase/caseinase activity ratio of less than about 0.80.
    Type: Grant
    Filed: January 17, 1995
    Date of Patent: November 25, 1997
    Assignee: Cognis Gesellschaft fuer Biotechnologie mbH
    Inventors: Karl-Heinz Maurer, Winfried Pochandke, Beatrix Kottwitz, Jorg Poethkow, Albrecht Weiss, Irmgard Schmidt, Horst Upadek
  • Patent number: H1776
    Abstract: A heavy duty, enzyme-containing, aqueous liquid detergent. The detergent includes surfactants, enzymes and an enzyme-stabilizing system. The detergent has a neat liquid pH of 9.5 or greater, a solution pH or 8.5 or greater at 0.2% weight use level and a titratable alkalinity of at least 0.5% weight per gram of product when expressed as % Na.sub.2 O as measured to pH 7.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: January 5, 1999
    Inventors: Jack E. Linard, Daniel J. Fox