C(=o)o Attached Directly Through The Carbon To A Benzene Ring Patents (Class 514/544)
-
Patent number: 8673971Abstract: The present invention discloses 4-nerolidylcatechol and its derivatives isolated from South American/Amazon plants (Pothomorphe species) and their potential use as therapeutical agent for treatment of malarial symptoms, including malarial patients resistant to traditional drugs. The present invention also discloses a method for producing 4-nerolidylcatechol and their derivatives.Type: GrantFiled: December 28, 2007Date of Patent: March 18, 2014Assignee: Instituto Nacional de Pesquisa de Amazonia INPAInventors: Ana Cristina Da Silva Pinto, Márcia Rúbia Silva Melo, Valter Ferreira De Andrade Neto, Francisco Célio Maia Chaves, Pedro Paulo Ribeiro Vieira, Adrian Martin Pohlit
-
Publication number: 20140057979Abstract: The present invention provides substances that can be used in a broad range of applications and effectively regulate clock gene expression. Provided is a clock gene expression regulating agent comprising, as an active ingredient, one or more selected from the group consisting of caryophyllene oxide and compounds represented by the following structural formula: wherein X is CH3, NH2 or NHCH3.Type: ApplicationFiled: October 15, 2013Publication date: February 27, 2014Applicant: Shiseido Company, Ltd.Inventors: Yoko Gozu, Shinichiro Haze
-
Patent number: 8642532Abstract: This invention is a method of using a class of excipients for protein formulation to reduce and/or eliminate protein aggregation in solutions or solids. This class of compounds contains carbonyl group(s) to form Schiff base(s) with amino groups of proteins and also contains moieties to keep protein molecules spatially separated. This method has never been disclosed anywhere in the literature.Type: GrantFiled: November 17, 2008Date of Patent: February 4, 2014Inventor: Guohan Yang
-
Publication number: 20140031304Abstract: The present invention provides novel compounds with hypocholesteremic activity from crude Embilica officinialis (EO) extracts and methods of use. The invention also provides nutraceuticals.Type: ApplicationFiled: July 19, 2013Publication date: January 30, 2014Inventors: Subroto Chatterjee, Mark S. Butler, Brinda Somanadhan
-
Patent number: 8633244Abstract: The invention relates to the use of esters of 2-propylheptanol with benzoic acid and/or benzoic acid derivatives in cosmetic and/or pharmaceutical preparations. The compounds are distinguished by their particularly light sensory impression.Type: GrantFiled: September 12, 2012Date of Patent: January 21, 2014Assignee: Cognis IP Management GmbHInventor: Markus Dierker
-
Publication number: 20130324597Abstract: This invention pertains to an anti-microbial, in particular anti-bacterial, more particularly against Gram?bacteria, and/or anti-fungal composition comprising as active blend trans-cinnamaldehyde and a potentiating agent, and to the potentiating agent. In particular this composition is intended for preventing and/or treating microbial infection in an animal.Type: ApplicationFiled: December 9, 2011Publication date: December 5, 2013Applicant: SEPTEOSInventor: Nicolas Tesse
-
Publication number: 20130316985Abstract: A pharmaceutical composition including at least one compound of the Formulas (I), (II), or (III), or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, as defined herein. Also disclosed is a method of treatment of diseases which are pathophysiologically related to GPR35, the GPR35-hERG signaling complex, or both, as defined herein.Type: ApplicationFiled: May 20, 2013Publication date: November 28, 2013Applicant: Corning IncorporatedInventors: Huayun Deng, Ye Fang
-
Publication number: 20130296323Abstract: This invention relates to geranylgeranyl acetone (GGA) derivatives and the use of GGA, its isomers, and GGA derivatives in methods for inhibiting neural death, increasing neural activity, increasing axon growth and cell viability, and increasing the survival rate of subjects administered the GGA or GGA derivatives.Type: ApplicationFiled: February 27, 2013Publication date: November 7, 2013Applicant: COYOTE PHARMACEUTICALS, INC.Inventors: Hiroaki Serizawa, Ankush B. Argade, Akash Datwani, Natalie Spencer, Yonghua Pan, Florian Ermini
-
Patent number: 8575215Abstract: A method of treating a neurodegenerative or cardiovascular disorder with a compound of the following formula: in which X, Y, A1, A2, R1, and R2 are defined herein.Type: GrantFiled: February 18, 2010Date of Patent: November 5, 2013Inventors: Yangsheng Du, Martin R. Farlow, Ruyu Du
-
Patent number: 8563535Abstract: An aqueous gel composition of the present invention comprising about 0.1 to 0.3 wt % adapalene and about 2.5 to 5.0 wt % benzoyl peroxide, as active ingredients, wherein both the active ingredients are stabilized in hydrophilic gelling matrix of pH dependent gelling agent comprising crosslinked, acrylic acid-based polymer(s).Type: GrantFiled: March 23, 2012Date of Patent: October 22, 2013Inventors: Kamal Mehta, Lalatendu Panigrahi, Uday Kumar Nayak, Balakrishna Patro
-
Publication number: 20130178527Abstract: The present invention relates to a method for the prevention or treatment of degenerative neurological brain disorders and, more specifically, relates to a method for the prevention or treatment of degenerative neurological brain disorders, such as Parkinson's disease, Alzheimer's dementia (senile dementia), stroke, Lou Gehrig's disease, Pick's disease, Creutzfeldt-Jakob disease, Huntington's disease, progressive supranuclear palsy, spinocerebellar degeneration, cerebellar atrophy, multiple sclerosis, post-traumatic stress disorder, and amnesia. The method includes administering to a subject in need thereof a therapeutically effective amount of a composition, wherein the composition contains a paraben compound as an active ingredient having effects that are useful in combating oxidation to remove active oxygen, suppressing cell-death, improving impaired movement, and enhancing declining memory.Type: ApplicationFiled: May 18, 2011Publication date: July 11, 2013Applicant: BRAINTROPIA CO., LTD.Inventors: Yoo-Hun Suh, Sushruta Koppula, Su-Jin Noh
-
Publication number: 20130178526Abstract: This invention relates to compositions, methods, devices and kits relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock solution provided by the invention includes citrate and a paraben. The solution preferably has a density suitable for retention of the solution in a catheter during the lock period. Another lock solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.Type: ApplicationFiled: February 27, 2013Publication date: July 11, 2013Applicant: Ash Access Technology Inc.Inventors: Stephen R. Ash, Janusz Steczko, Gary L. Swanson
-
Patent number: 8481519Abstract: A method for isolating atraric acid from biological material, atraric acid derivatives, the chemical synthesis thereof, and the use of atraric acid and the derivatives thereof for treating or producing a medicament for treating benign prostate hyperplasia, prostate carcinoma or spinobulbar muscular atrophy is provided. In addition, a basic substance for the development of other agents used for treating benign prostate hyperplasia, prostate carcinoma, or spinobulbar muscular atrophy is provided.Type: GrantFiled: January 28, 2006Date of Patent: July 9, 2013Assignee: LTS Lohmann Therapie-Systeme AGInventors: Hans-Rainer Hoffmann, Rudolf Matusch, Aria Baniahmad
-
Publication number: 20130172355Abstract: The invention relates to a sulfur-containing compound and the preparation thereof. The invention also relates to the uses of the sulfur-containing compound in inhibiting inducible nitric oxide synthase and/or cyclooxygenase-2 and in treating the diseases associated with inducible nitric oxide synthase and/or cyclooxygenase-2. This invention also describes a series of chemical analogues of the said sulfur-containing compound and the preparation of these compounds.Type: ApplicationFiled: February 6, 2013Publication date: July 4, 2013Applicant: NATIONAL SUN YAT-SEN UNIVERSITYInventor: NATIONAL SUN YAT-SEN UNIVERSITY
-
Publication number: 20130143964Abstract: Disclosed are a sympathetic inhibitor allowing more effective inhibition of activity of a sympathetic nerve, as well as a cosmetic composition, a food, and a sundry article containing the same. Ethyl 4-methoxybenzoate is efficacious for quieting down the activity of the sympathetic nerve. The sympathetic inhibitor, the cosmetic composition, the food and the sundry article containing the same enable more effective inhibition of the activity of the sympathetic nerve.Type: ApplicationFiled: May 26, 2011Publication date: June 6, 2013Inventors: Keiko Mori, Shinichiro Haze, Yoko Gozu, Atsushi Joichi
-
Publication number: 20130108564Abstract: The present invention relates to compounds having general formula (I): CH3—(CH?CH)n—R??(I) where: n=3, 5, 7; R is chosen from —CH2—O—CO—R?, —CO—OR? or —CO—O(?), R? is chosen from H, C1-C22 alkyl or alkenyl, aryl or aralkyl, or sugars; and their pharmaceutically acceptable salts, such as sodium, potassium and lysine salts, for use as the active ingredient in pharmaceutical or cosmetic compositions for improving the pigmentation of the human skin, treating pigmentation disorders and/or improve both the photoprotective capacity of the skin and the intensity of its suntan.Type: ApplicationFiled: July 15, 2011Publication date: May 2, 2013Applicant: GIULIANI S.P.A.Inventors: Giammaria Giuliani, Ralf Paus, Yuval Ramot, Astrid Becker, Sergio Baroni
-
Publication number: 20130090355Abstract: The present invention provides methods of preventing or inhibiting tumor metastasis in a subject by administering a therapeutically effective amount of (1) a compound from a group of enumerated compounds, or a pharmaceutically acceptable salt thereof; (2) an agent that covalently modifies at least one cysteine residue of S100A4 protein; or (3) an agent that inhibits the interaction between S100A4 and myosin-IIA.Type: ApplicationFiled: April 28, 2011Publication date: April 11, 2013Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITYInventor: Anne R. Bresnick
-
Publication number: 20130085179Abstract: The present disclosure provides methods for evaluating daily ammonia exposure based on a single fasting ammonia blood level measurement, as well as methods that utilize this technique to adjust the dosage of a nitrogen scavenging drug, determine whether to administer a nitrogen scavenging drug, and treat nitrogen retention disorders.Type: ApplicationFiled: March 9, 2012Publication date: April 4, 2013Inventors: Bruce SCHARSCHMIDT, Masoud Mokhtarani
-
Publication number: 20130071412Abstract: The invention features a powdered composition including a pharmaceutically active compound and a protein or a hydrolyzed protein. In particular, the powdered composition forms a stable solution or dispersion suitable for oral administration in which the protein or the hydrolyzed protein is bound to the pharmaceutically active compound. The invention also provides a method of administering the composition, such as to a patient with dysphasia; liquid or semi-solid formulations of the composition; methods for preparing the composition; and kits including the composition.Type: ApplicationFiled: December 17, 2010Publication date: March 21, 2013Applicant: Exodos Life Sciences Limited PartnershipInventors: Harry J. Leighton, Crist J. Frangakis
-
Publication number: 20130053354Abstract: Provided is a bone-transplant or bone-filling composition, which comprises a dihydroxybenzoic acid derivative which has been newly demonstrated to increase the activity of osteoblasts and so induce bone formation.Type: ApplicationFiled: April 25, 2011Publication date: February 28, 2013Inventor: Jae-Jin Han
-
Patent number: 8362076Abstract: Ascorbic acid esters of resveratrol and topical compositions containing same.Type: GrantFiled: November 11, 2011Date of Patent: January 29, 2013Assignee: ELC Management LLCInventors: Daniel H. Maes, Fatemeh Mohammadi, Lisa Qu, Anna Czarnota, Thomas Mammone, Lieve Declercq, Julius R. Zecchino
-
Patent number: 8357398Abstract: Oral dosage forms of benzonatate useful for anti-tussive and anti-tussive/combination applications.Type: GrantFiled: October 20, 2010Date of Patent: January 22, 2013Assignee: Alitair Pharmaceuticals Inc.Inventors: William Wayne Howard, Russell Francis Somma, Doreen Marie Frank
-
Publication number: 20130004555Abstract: The invention relates to the use of esters of 2-propylheptanol with benzoic acid and/or benzoic acid derivatives in cosmetic and/or pharmaceutical preparations. The compounds are distinguished by their particularly light sensory impression.Type: ApplicationFiled: September 12, 2012Publication date: January 3, 2013Applicant: Cognis IP Management GmbHInventor: Markus Dierker
-
Publication number: 20120328541Abstract: Compounds of the formulae and selected hindered nitroxyl, hydroxylamine and hydroxylamine salt compounds such as the compound of the formula wherein G1 is hydrogen; C1-C22alkyl; C1-C22alkylthio; C2-C22alkylthioalkyl; C5-C7cycloalkyl; phenyl; C7-C9-phenylalkyl; or SO3M; G2 is C1-C22alkyl; C5-C7cycloalkyl; phenyl; or C7-C9-phenylalkyl; E is oxyl or hydroxyl; V is —O—; or —NH—; a is 0 or 1 or 2; b, c and d and g are each independently of one another 0 or 1; e is an integer from 1 to 4; f, m, n and p are each independently of one another an integer from 1 to 3; q is 0 or an integer from 1 to 3; Q, T and G3 are as defined in claim 1; G4 and G5 are each independently of the other hydrogen; or C1-C22alkyl; exhibit marked antiinflammatory action.Type: ApplicationFiled: September 5, 2012Publication date: December 27, 2012Inventors: Werner Baschong, Oliver Reich, Sébastien Mongiat
-
Publication number: 20120329649Abstract: This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.Type: ApplicationFiled: June 21, 2012Publication date: December 27, 2012Inventors: James E. Hunter, William C. Lo, Gerald B. Watson, Akshay Patny, Gary D. Gustafson, Dan Pernich, William K. Brewster, Debra L. Camper, Beth Lorsbach, Michael R. Loso, Thomas C. Sparks, Hemant Joshi, Adiraj Mandaleswaran, Ramadevi Sanam, Rambabu Gundla, Pravin S. Iyer
-
Publication number: 20120321571Abstract: The present invention provides paraben compositions and associated methods and reagents, particularly useful for the treatment of dermatologic conditions. In some embodiments, provided compositions are formulated for and achieve transdermal delivery, for example by topical administration.Type: ApplicationFiled: January 23, 2012Publication date: December 20, 2012Applicant: ANTERIOS, INC.Inventors: Jonathan EDELSON, Timothy KOTYLA, Klaus THEOBALD
-
Publication number: 20120322717Abstract: The present invention relates to the field of therapeutic methods to screen for compounds on the basis of their ability to influence Wnt activity. The screening process is applied to both a physical library of a series of compounds and a virtual library of compounds that affect Wnt activity. In one aspect, the virtual screening process could be carried out where a permutational library of small peptides is substituted for the small organic molecules. The inventive methods may be used to empirically test for effects on Wnt activity and may also be applied to any pair of proteins involved in protein-protein interactions.Type: ApplicationFiled: May 22, 2009Publication date: December 20, 2012Inventors: Dakai Liu, Xiaofeng Li, Richard Jin, Yuaxin Liang, Wei Cheng, Riddhi Bhattacharyya, Guangrong Zhang
-
Publication number: 20120277314Abstract: This invention relates to compositions, methods, devices and kits relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock solution provided by the invention includes citrate and a paraben. The solution preferably has a density suitable for retention of the solution in a catheter during the lock period. Another lock solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.Type: ApplicationFiled: July 11, 2012Publication date: November 1, 2012Applicant: Ash Access Technology Inc.Inventors: Stephen R. Ash, Janusz Steczko, Gary L. Swanson
-
Publication number: 20120277312Abstract: The use of ethyl gallate methyl gallate or 3,4-dihydroxybenzoate for treatment of septic shock Said compounds may also prophylactically treat septic shock via administration to a subject before the development of a fall in blood pressure.Type: ApplicationFiled: February 24, 2010Publication date: November 1, 2012Inventors: Steven N. Mink, Hans Jacobs
-
Publication number: 20120277313Abstract: The present invention relates to a cosmetic composition having a high content of a stable oil phase, and more particularly to a cosmetic composition, which combines advantages of spreadability and softness of an oil-in-water type with emollient effect and water resistance of a water-in-oil type as a resulting of stabilizing, based on the total weight of the composition, 30-56 wt % of an oily component by multiple emulsification of W/O/W, and which provides skin moisturizing and softening ef-fects by a large amount of oil components, and also which allows irritations caused by active ingredients to be relieved by a high content of the oily component.Type: ApplicationFiled: November 26, 2010Publication date: November 1, 2012Inventors: Lee Kyoung Kwon, Go Un Han, Jun Oh Kim, Jeong Cheol Ha, Youn Joon Kim, Sang Hoon Han
-
Publication number: 20120270938Abstract: A family of covalent kinetic stabilizer compounds that selectively and covalently react with the prominent plasma protein transthyretin in preference to more than 4000 other human plasma proteins is disclosed. A contemplated compound corresponds in structure to Formula I, below, where the various substituents are defined within, and reacts chemoselectively with one or two of four Lys-15 ?-amino groups within the transthyretin tetramer. The crystal structure confirms the binding orientation of the compound substructure and the conjugating amide bond. A covalent transthyretin kinetic stabilizer exhibits superior amyloid inhibition potency, compared to a non-covalent counterpart, and inhibits cytotoxicity associated with amyloidogenesis.Type: ApplicationFiled: October 14, 2010Publication date: October 25, 2012Inventors: Jeffery W. Kelly, Sungwook Choi
-
Patent number: 8288436Abstract: The invention relates to the use of esters of 2-propylheptanol with benzoic acid and/or benzoic acid derivatives in cosmetic and/or pharmaceutical preparations. The compounds are distinguished by their particularly light sensory impression.Type: GrantFiled: April 17, 2008Date of Patent: October 16, 2012Assignee: Cognis IP Management GmbHInventor: Markus Dierker
-
Publication number: 20120238624Abstract: Formulations and methods are provided for the treatment of pain, and neuropathic pain in particular. The formulations are eutectic mixtures of a capsaicinoid and a local anesthetic agent and/or an anti-pruritic agent.Type: ApplicationFiled: September 14, 2011Publication date: September 20, 2012Inventor: Manoj Maniar
-
Publication number: 20120220654Abstract: A concentrated poly(ethylene glycol) solution that has good stability for extended storage is provided for use as a laxative. The concentrated solution comprises water, sodium benzoate, poly(ethylene glycol), and enough acid to yield a solution having a pH at 25° C. in the range 3.0-5.0. It is prepared and packaged to minimize the accumulation of degradation products.Type: ApplicationFiled: October 24, 2011Publication date: August 30, 2012Inventors: Joseph P. Reo, Kevin C. Fowler, Mohammed A. Kabir, Michael P. Tune, Dennis Nelson, Anna W. Tai, Nanhye Kim
-
Patent number: 8226971Abstract: This invention relates to compositions, methods, devices and kits relating to the infusion of a catheter lock solution into an indwelling catheter. Inventive compositions, methods, devices and kits aid in diminishing the effects of microbial infection in catheters and occlusion of the catheters. A lock solution provided by the invention includes citrate and a paraben. The solution preferably has a density suitable for retention of the solution in a catheter during the lock period. Another lock solution provided by the invention includes citrate, a paraben and a photo-oxidant, such as, for example, methylene blue.Type: GrantFiled: June 2, 2010Date of Patent: July 24, 2012Assignee: Ash Access Technology, Inc.Inventors: Stephen R. Ash, Janusz Steczko, Gary L. Swanson
-
Publication number: 20120184513Abstract: The invention relates to organic compounds having the ability to reduce or suppress the onset of skin irritation induced by extraneous cause selected from the group of 2-heptylcyclopentanone, 2-ethoxynaphthalene; 2-methoxynaphthalene; 1-methoxy-4-(prop-1-enyl)benzene; 1-(cyclopropylmethyl)-4-methoxybenzene; wherein X, Y, and R1 to R11 have the same meaning as given in the description. Furthermore the invention refers to compositions for topical application to the skin comprising them. It further relates to a method of reducing or suppressing the formation of skin irritation.Type: ApplicationFiled: January 14, 2011Publication date: July 19, 2012Applicant: Givaudan SAInventors: Andreas NATSCH, Michael WASESCHA
-
Publication number: 20120178704Abstract: Stilbene compounds for the prevention and treatment of colon cancer or colon inflammation and methods of using same are provided.Type: ApplicationFiled: December 7, 2007Publication date: July 12, 2012Inventors: Agnes M. Rimando, Nanjoo Suh, Cassia Mizuno, Bandaru s. Reddy, Sada L. Reddy
-
Publication number: 20120172340Abstract: Methods for identifying selective activators of SIRT5 and/or SIRT1 and methods for using these selective activators in the modulation of SIRT5 and/or SIRT1 are provided.Type: ApplicationFiled: October 7, 2010Publication date: July 5, 2012Applicant: BIOMOL International L.P.Inventors: Konrad T. Howitz, Robert E. Zipkin
-
Patent number: 8198323Abstract: The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.Type: GrantFiled: April 12, 2010Date of Patent: June 12, 2012Assignees: The University of North Carolina at Chapel Hill, The University of Rochester Medical Center, Androscience CorporationInventors: Kuo-Hsiung Lee, Li Lin, Charles C-Y Shih, Ching-Yuan Su, Junko Ishida, Hironori Ohtsu, Hui-Kang Wang, Hideji Itokawa, Chawnshang Chang
-
Publication number: 20120107428Abstract: Provided herein are essential oils and synthetic compounds, and combinations thereof, as repellent compositions for repelling insects, such as vespid social wasps (Vespidae), including yellowjackets, paper wasps, and hornets. Controlled release devices comprising these repellent compositions are also provided.Type: ApplicationFiled: August 9, 2011Publication date: May 3, 2012Applicant: Sterling International Inc.Inventors: Rodney G. Schneidmiller, Qing-He Zhang, Doreen R. Hoover
-
Publication number: 20120095094Abstract: The invention relates to a process for cosmetic treatment, including the reduction of superficial and deep wrinkles, using ferutinine from Ferula spp extracts.Type: ApplicationFiled: December 13, 2011Publication date: April 19, 2012Applicant: INDENA S.P.A.Inventors: Ezio BOMBARDELLI, Gabriele Fontana, Aldo Cristoni, Enrico Mercalli
-
Publication number: 20120087871Abstract: Methods for killing insects and a nest are disclosed. The methods may be used to disrupt a colony of nestdwelling insects. The insects may include wasps, hornets, and yellowjackets.Type: ApplicationFiled: September 30, 2011Publication date: April 12, 2012Applicant: STERLING INTERNATIONAL INC.Inventors: Rodney G. Schneidmiller, Qing-He Zhang, Guiji Zhou, Doreen R. Hoover
-
Publication number: 20120082722Abstract: Disclosed are oral dosage forms containing a Ras antagonist including FTS and structural analogs thereof, and at least one pharmaceutically acceptable excipient other than a cyclodextrin, and methods of orally administering same to treat diseases and disorders responsive to the Ras antagonists.Type: ApplicationFiled: December 15, 2011Publication date: April 5, 2012Applicant: CONCORDIA PHARMACEUTICALS, INC.Inventor: Victor J. Bauer
-
Publication number: 20120077875Abstract: The present invention relates to a composition, in particular an antibacterial drug, including trans-cinnamaldehyde, a pharmaceutical composition including trans-cinnamaldehyde for treatment or prevention, in particular, of a nosocomial infection, specifically caused by a bacteria resistant to anti-bacterial drugs, the use of trans-cinnamaldehyde as an anti-bacterial agent and a method for preparing a surface including the application of a composition according to the invention.Type: ApplicationFiled: June 7, 2010Publication date: March 29, 2012Applicant: SEPTEOSInventor: Nicolas Tesse
-
Patent number: 8129362Abstract: Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).Type: GrantFiled: July 13, 2007Date of Patent: March 6, 2012Assignee: Galderma Research & DevelopmentInventors: Marie-Line Abou Chacra Vernet, Denis Gross, Christian Loesche, Michel Poncet
-
Publication number: 20120053133Abstract: A novel antiseptic agent composition which has a wide antimicrobial spectrum and excellent antiseptic properties is provided. An antiseptic agent composition A contains a glycerin hydroxy fatty acid monoester that is an ester of glycerin and a hydroxy fatty acid having 8 to 18 carbon atoms, and a specific antiseptic agent such as an alkanediol. An antiseptic agent composition B contains the glycerin hydroxy fatty acid monoester and an aromatic antiseptic agent. An antiseptic agent composition C contains the glycerin hydroxy fatty acid monoester and a chelating agent.Type: ApplicationFiled: January 18, 2010Publication date: March 1, 2012Applicant: TAIYO CORPORATIONInventors: Shuji Kanatani, Soota Iwamoto
-
Publication number: 20120029075Abstract: Described are antibacterial and anti-mould compositions containing high amounts of C1 to C7 organic acid mono-glycerides and glycerol, their preparation and their use in animal feedstuffs.Type: ApplicationFiled: March 16, 2010Publication date: February 2, 2012Inventor: Fernando Cantini
-
Patent number: 8106233Abstract: The present invention relates to the use of compounds of the formula (I), with radicals defined in the description, as antioxidants, to corresponding novel compounds and compositions, and to corresponding processes for the preparation of compounds and compositions.Type: GrantFiled: March 21, 2006Date of Patent: January 31, 2012Assignee: Merck Patent GmbHInventors: Thomas Rudolph, Herwig Buchholz
-
Patent number: 8080537Abstract: Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO.Type: GrantFiled: May 28, 2009Date of Patent: December 20, 2011Assignee: Galderma Research & DevelopmentInventors: Marie-line Abou-Chacra Vernet, Denis Gross, Christian Loesche, Michel Poncet
-
Publication number: 20110300083Abstract: Personal care formulations containing alkyl ketal esters having the structure wherein a is 0 or an integer of 1 to 12; b is 0 or 1; R2 is a divalent C1-8 group optionally substituted with up to 5 hydroxyl groups; and R1 is C1-6 alkyl.Type: ApplicationFiled: May 10, 2011Publication date: December 8, 2011Applicant: SEGETIS, INC.Inventors: Dorie J. YONTZ, Lee Richard RIETH, Nicholas MORANTE, Irwin PALEFSKY