Z Contains An Unbroken Chain Of At Least Seven Carbon Atoms Bonded Directly To The C(=o) Group Patents (Class 514/552)
  • Publication number: 20120114725
    Abstract: The present invention relates to an information medium to be handled by a large number of users, such as a banknote, and having antiviral properties, and to a method for making same.
    Type: Application
    Filed: May 7, 2010
    Publication date: May 10, 2012
    Applicant: ARJOWIGGINS SECURITY
    Inventor: Henri Rosset
  • Publication number: 20120108658
    Abstract: Disclosed is an ophthalmic composition which is characterized by containing (A) a vitamin A, (B) a polyoxyethylene polyoxypropylene glycol, and (C) an oil component that is selected from the group consisting of castor oil, soybean oil, sesame oil, peanut oil, olive oil, almond oil, wheat germ oil, corn oil, rapeseed oil, sunflower oil, purified lanolin and gel hydrocarbon.
    Type: Application
    Filed: June 29, 2010
    Publication date: May 3, 2012
    Inventors: Akito Odaka, Chieko Inoue, Manabu Hattori, Nobuhito Tabuchi
  • Publication number: 20120108661
    Abstract: The emulsion composition of the present invention contains (A) 0.001 to 10 wt. % of an organic compound having two or more hydroxyl groups, an inorganic value of 220 to 450, and an organic value of 300 to 1,000; (B) 0.001 to 10 wt. % of an organic compound having one hydroxyl group, an inorganic value of 100 to 200, and an organic value of 280 to 700; (C) 0.001 to 10 wt. % of a compound represented by formula (2): wherein R1 is a C4 to C30 hydrocarbon group; Z is a methylene group, a methine group, or an oxygen atom; X1, X2, X3 is a hydrogen atom, a hydroxyl group, or an acetoxy group; X4 is a hydrogen atom, an acetyl group, or a glyceryl group; each of R2 and R3 a hydrogen atom, a hydroxyl group, a hydroxymethyl group, or an acetoxymethyl group; R4 is a C5 to C60 hydrocarbon group; and R5 is a hydrogen atom or a hydrocarbon group containing 1 to 30 carbon atoms in total; (D) 0.00012 to 10 wt.
    Type: Application
    Filed: July 6, 2010
    Publication date: May 3, 2012
    Applicant: KAO CORPORATION
    Inventors: Masanori Orita, Tomokazu Yoshida, Chihiro Ueyama
  • Publication number: 20120095097
    Abstract: Disclosed is an ophthalmic composition containing (A) not less than 50,000 units/100 mL of vitamin A, (B) not less than 0.4 W/V % of a polyoxyethylene polyoxypropylene glycol, and (C) trometamol.
    Type: Application
    Filed: June 25, 2009
    Publication date: April 19, 2012
    Inventors: Nobuhito Tabuchi, Chieko Inoue, Manabu Hattori, Miyuki Miyake, Hazuki Tsutsui
  • Patent number: 8158680
    Abstract: The present invention relates to the use of one or more esters of 2-hexyldeconal having fatty acids of the general formula (I) R1-COOH, wherein R1 is a linear or branched, saturated or unsaturated alkyl radical having 1 to 6 carbon atoms, in and/or for the production of cosmetic and/or pharmaceutical preparations.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: April 17, 2012
    Assignee: Cognis IP Management GmbH
    Inventors: Achim Ansmann, Markus Dierker
  • Publication number: 20120064171
    Abstract: Stable non-toxic pesticide composition having fungicidal and insecticidal properties including a pesticide that is nontoxic to mammals; one or more disinfectants; a vegetable oil; and one or more stabilizing agents. In one example, one or more stabilizing agents are selected and are present in an amount in combination with the selection and amount of a pesticide, one or more disinfectants, and a vegetable oil to provide the composition with a stability upon application to a substrate effective to allow lethality against one or more target pests.
    Type: Application
    Filed: November 21, 2011
    Publication date: March 15, 2012
    Applicant: BEDO HOLDING AG
    Inventor: Thomas Besendorfer
  • Publication number: 20120034176
    Abstract: The present invention relates to a compound of the general formula (I) where: X?S, SO or SO2; and one of the radicals R1 and R2 is a hydrogen atom and the other is a radical: a C1 to C18 linear or branched alkyl, optionally substituted by one or more halogen atom(s); a C2 to C18 linear or branched alkenyl, optionally substituted by one or more halogen atom(s); an aralkyl, optionally substituted by one or more C1 to C6alkoxy group(s); or a COR3 or CONHR3, but not simultaneously, where R3 is a radical: a C1 to C18 linear or branched alkyl, optionally substituted by one or more halogen atom(s); a C2 to C18 linear or branched alkenyl, optionally substituted by one or more halogen atom(s); an aralkyl, optionally substituted by one or more C1 to C6alkoxy group(s); an aralkenyl, optionally substituted by one or more C1 to C6 alkoxy groups and/or one or more OH group(s); or an aryl radical, optionally substituted by one or more C1 to C6 alkoxy group(s).
    Type: Application
    Filed: April 8, 2010
    Publication date: February 9, 2012
    Applicant: PIERRE FABRE DERMO-COSMETIQUE
    Inventor: Stéphane Poigny
  • Publication number: 20120029077
    Abstract: The invention is directed to an animal feed suitable for feeding mammals, birds and fish, comprising an alkyl ester of a fatty acid, wherein said fatty acid has a chain length of 5-12 carbon atoms, and wherein the dosage of said ester in said animal feed is 50 ppm by weight or higher, based on the total weight of said animal feed.
    Type: Application
    Filed: January 25, 2010
    Publication date: February 2, 2012
    Inventors: Yanming Han, Coenraad Henricus Maria Smits, John Brennan, Gregory Ian Page, Johannes Teunis Pieter Van Dam
  • Patent number: 8106093
    Abstract: A method for treating glycogen storage disease by administering an effective amount of a composition that includes ketogenic odd carbon fatty acids that ameliorate the symptoms of these diseases.
    Type: Grant
    Filed: July 1, 2005
    Date of Patent: January 31, 2012
    Assignee: Baylor Research Institute
    Inventor: Charles R. Roe
  • Patent number: 8101163
    Abstract: The present invention is directed to transdermal compositions and the uses thereof. These compositions include at least one of the following components: a C1-C6 dialkyl, C12-C30 dialkyl quaternary ammonium salt, a C12-C30 fatty acid, a nitrogenous organic base, C12-30 fatty alcohol, monoglyceride or the reaction products thereof.
    Type: Grant
    Filed: December 3, 2009
    Date of Patent: January 24, 2012
    Assignee: Microdermis Corporation
    Inventor: Griscom Bettle, III
  • Publication number: 20120015894
    Abstract: An aqueous hair cleansing agent contains a sulfate-type anionic surfactant having a specific structure, an ether carboxylate-type anionic surfactant having a specific structure, and an organic carboxylic acid or salt thereof, thereby has a pH of 1 to 5 at 25° C. when diluted 20-fold with water.
    Type: Application
    Filed: March 26, 2010
    Publication date: January 19, 2012
    Applicant: KAO CORPORATION
    Inventor: Eiji Terada
  • Publication number: 20120009285
    Abstract: A personal care composition comprising: at least a first phase and a second phase wherein said first phase comprises a) an aqueous structured surfactant phase comprising STnS where n is between about 0 and about 2.5; b) ; c) a structuring system comprising i. optionally, a non-ionic emulsifier; ii. optionally, from about 0.05% to about 5%, by weight of said personal care composition, of an associative polymer; iii. an electrolyte; and said second phase comprises a) a benefit phase comprising from 1% to about 50%, by weight of said personal care composition, of a hydrophobic benefit agent.
    Type: Application
    Filed: June 10, 2011
    Publication date: January 12, 2012
    Inventors: Karl Shiqing WEI, Edward Dewey Smith, III, Shawn Lynn Mansfield, Peter Herbert Koenig, Wei Ji, Yogesh Suradkar, Deepa Bagchi, Sujatha Logou, Stevan David Jones
  • Publication number: 20120003198
    Abstract: The invention relates to the improvement of visual performance, particularly of visual performance in the darkness, by administration of a colorant that is capable of being incorporated into eye tissue and/or causing yellowing of eye tissue, especially carotenoids, such as lutein and zeaxanthin.
    Type: Application
    Filed: September 8, 2011
    Publication date: January 5, 2012
    Applicant: DSM IP ASSETS B.V.
    Inventors: Felix Barker, Regina Goralczyk, Wolfgang Schalch
  • Publication number: 20110312917
    Abstract: The present invention relates to a cleaning composition for removing cellular components from tissue for transplantation derived from humans and animals. More particularly, the present invention relates to a cleaning composition for treating tissue for transplantation comprising a polyoxyethyleneglycol C14-C20alkyl ether as a first protein solubilizing component, a C6-C8alkylphenol polyethoxylate as a first lipid solubilizing component, a C10-C16alkyl glycoside as a second protein solubilizing component and a C9-C12 alkylphenoxy polyethoxy ethanol as a second lipid solubilizing component.
    Type: Application
    Filed: February 10, 2010
    Publication date: December 22, 2011
    Applicant: CG BIO CO., LTD.
    Inventors: Byoung Suck Kim, Seok Beom Song, Goo Won Jeong, Hyo Jung Kang, Jae Deuck Jung
  • Publication number: 20110305646
    Abstract: The present invention relates to a method of treating a fungal condition caused by T. rubrum, by administering a composition comprising a fatty acid monoester of glycerol. According to an embodiment, the fatty acid monoester of glycerol is 1-monocaprin. According to another embodiment, the fungal condition is onychomycosis.
    Type: Application
    Filed: March 19, 2010
    Publication date: December 15, 2011
    Inventors: Jon Lenn, Hans Hofland, Barry Hunt, Edward Hsia
  • Publication number: 20110301237
    Abstract: Methods of making a liquid crystal mixture essentially comprised of at least one fatty acid ester or fatty acid, at least one polyhydric solvent, and at least one alkali reactant. The resultant mixture includes at least one fatty acid ester or fatty acid, at least one polyhydric solvent, and at least one salt of said fatty acid ester or fatty acid. The resultant mixture exhibits enhanced stability and aqueous solubility of fatty acids and fatty acid esters. When medium chain fatty acid monoglycerides are used in the method, the resultant mixture exhibits antimicrobial efficacy.
    Type: Application
    Filed: October 18, 2010
    Publication date: December 8, 2011
    Applicant: COPPERHEAD CHEMICAL COMPANY
    Inventors: Richard Peter Curtis Calvert, Charles D. Cappuccino, James David Mosbaugh, Edmund L. Phelan
  • Publication number: 20110300095
    Abstract: Compositions comprising undecylenic acid or citric acid and certain esters are effective for reducing malodors. The esters are in the molecular weight range of between 150-200 when the acid is undecylenic acid and in the range of between 130-230 when the acid is citric acid. These compositions can be used in perfumed products, household products and personal care products.
    Type: Application
    Filed: December 21, 2010
    Publication date: December 8, 2011
    Inventors: STEPHEN V. DENTE, Ketrin Leka, Brian Fielder, Garry Johnson
  • Publication number: 20110294765
    Abstract: Processes for obtaining aqueous dispersions comprising alcohols and acids obtained by hydrolysis of jojoba oil. Hydrolyzed jojoba oil products are treated by a process comprising neutralization of jojoba fatty acids with aliphatic organic amines dissolved in a co-solvent followed by the dispersion of both the neutralized fatty acids together with jojoba alcohols in an aqueous medium. The products obtained, generically named hydrolyzed jojoba oil (HJO), promote transdermal absorption and are useful vehicles for carrying a wide range of pharmaceutical and cosmetic compositions, including pharmaceutical and cosmetic compositions comprising either lipophilic or hydrophilic active principles. The HJO can also be used to produce a semisolid, self-emulsified jojoba oil (SEJO), obtained by emulsifying the HJO in jojoba oil.
    Type: Application
    Filed: April 11, 2011
    Publication date: December 1, 2011
    Inventors: Rubén Hilario Manzo, Norma Graciela Maggia
  • Publication number: 20110288170
    Abstract: Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.
    Type: Application
    Filed: March 7, 2011
    Publication date: November 24, 2011
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Krzysztof Palczewski, Matthew Batten
  • Publication number: 20110281946
    Abstract: The present invention concerns polymeric-based compositions that are useful in the delivery and sustained release of hydrophobic therapeutic and/or cosmetic agents substantially at the point of injury, infection or, in the case of purely cosmetic applications, the point of treatment. Also provided are methods of preparing such compositions and methods of treatments involving the use of such compositions.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 17, 2011
    Applicant: NORTHERN HYDROGELS LTD
    Inventor: Alan John WADDON
  • Patent number: 8048920
    Abstract: Biodegradable personal care compositions comprising 1,3-propanediol are provided, and the 1,3-propanediol in the composition is biologically derived. The compositions exhibit a lower anthropogenic CO2 emission profile. Also provided are biodegradable personal care compositions comprising an ester of 1,3-propanediol. In these compositions, the ester can have at least 3% biobased carbon.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: November 1, 2011
    Assignee: DuPont Tate & Lyle Bio Products Company, LLC
    Inventors: Melissa Joerger, Gyorgyi Fenyvesi, Raja Hari Poladi, Ann Wehner, Irwin A. Palefsky
  • Publication number: 20110251277
    Abstract: One aspect of the invention is a new foam which includes a liquid having a plurality of bubbles therein and a plurality of particles suspended therein. The foam is made in a dispenser that suspends the bubbles in the liquid. The liquid may be a single liquid with particles therein or may be made from two liquids which are mixed together. The particles may be such that, prior to foaming the particles sink, float or are suspended in the liquid.
    Type: Application
    Filed: November 11, 2010
    Publication date: October 13, 2011
    Applicant: DEB IP LIMITED
    Inventors: Shaun Kerry MATTHEWS, Stewart BANKS, Kara Catherine STONEHOUSE
  • Publication number: 20110243863
    Abstract: The invention relates to cosmetic and/or pharmaceutical formulations, comprising n-octyl-n-octanoate.
    Type: Application
    Filed: October 12, 2009
    Publication date: October 6, 2011
    Inventors: Rolf Kawa, Bettina Jackwerth
  • Publication number: 20110224299
    Abstract: Compositions comprising high amounts of low melting point waxes are provided in self-supporting solid or semi-solid form. The low melting point waxes are stabilized in the compositions by the presence of small amounts of higher melting wax. The compositions may provide a cooling sensation when applied to the skin.
    Type: Application
    Filed: July 20, 2010
    Publication date: September 15, 2011
    Applicant: Avon Products, Inc.
    Inventors: William E. McNamara, Mark S. Garrison, Thi N. Do
  • Publication number: 20110218245
    Abstract: The object of the present invention is the use of compounds designed to inhibit the activity of the enzyme 5?-reductase. This is a novel use of compounds of general formula (I): CH3(—CH?CH)n—R??(I) where n=from 2 to 7, and R is chosen from among: CHO, CH2OH, CH2O—CO—R?, CO—O(?), where R? is chosen from among H, and the alky from C1 to C22, each compound of general formula (I) being used as such or in mixtures with other compounds, as the active principle in a pharmaceutical or cosmetic composition designed to inhibit the action of the enzyme 5?-reductase, and of the pharmaceutical or cosmetic compositions deriving therefrom.
    Type: Application
    Filed: November 10, 2009
    Publication date: September 8, 2011
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria Giuliani, Anna Benedusi, Sergio Baroni
  • Publication number: 20110218180
    Abstract: The present invention relates to the formulations of ester derivatives of capsaicin and ester derivatives of myristoleic acid. These derivatives are capable of reverting to the active parent compound following enzymatic or chemical hydrolysis. These derivatives have a higher lipophilicity, lipid solubility and less irritation to the skin than the parent compound, and hence are better able to be incorporated into certain pharmaceutical formulations, including cream and ointment pharmaceutical formulations. The pharmaceutical compositions of the present invention contain a compound of following formula (Ia): R—CO—CAP??(Ia) wherein CAP refers to collectively the capsaicins represented in FIG. 1 and a compound of formula (Ib): MCO—O—R??(Ib) wherein MCO refers to myristoleic acid.
    Type: Application
    Filed: May 16, 2011
    Publication date: September 8, 2011
    Applicant: Trinity Laboratiories, Inc.
    Inventors: Chandra Ulagaraj Singh, Jagaveerabhadra Rao Nulu
  • Publication number: 20110213031
    Abstract: The present invention aims to provide a novel type I natural ceramide derivative having a structure more similar to that of a type I natural ceramide composed of sphingosine and an ?-acyloxy long-chain carboxylic acid; and a method for producing the same. The derivative is provided by reacting an ?-acyloxy long-chain fatty acid derivative with dihydrosphingosine or a salt thereof. The thus produced novel type I natural ceramide derivative, when combined with other ceramides, can significantly improve the compatibility of ceramides, which facilitates preparation of a composition containing ceramides, such as a moisturizer or a cosmetic, and also increases the storage stability of the composition.
    Type: Application
    Filed: September 30, 2009
    Publication date: September 1, 2011
    Inventors: Tatsuyoshi Tanaka, Kazumi Okuro
  • Patent number: 7994219
    Abstract: Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. The BPI inducing agents include, for example, lipoxin compounds.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: August 9, 2011
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Charles N. Serhan, Sean P. Colgan
  • Patent number: 7994157
    Abstract: Disclosed are a method for dispersing plant sterol for beverage and a plant sterol-dispersed beverage, of which particle size is nanometer-scale in dispersed beverage. The dispersion of plant sterols starts with the admixing of plant sterol to at least one emulsifier selected from the group consisting of sucrose fatty acid ester, sorbitan fatty acid ester and polyglycerine fatty acid ester, followed by melting the admixture by heating at 60 to 200° C. Afterwards, the molten substance is mixed with an aqueous beverage alone or an emulsifier-containing aqueous beverage in state of its own molten type or power type. This resulting mixture is stirred at a high speed to give a dispersion of plant sterols in an aqueous beverage. The beverage is superior in bioavailability, having good mouth feel, transparent aspect and no influence on the characteristic taste, flavor and color of the beverages.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: August 9, 2011
    Assignee: KIP Biotech LLC
    Inventors: Won-Tae Yoon, Kab-Sig Kim, Bo-Chun Kim, Jung-Hee Han, Hyung-Pyo Hong
  • Publication number: 20110189257
    Abstract: There are provided compositions and methods to aggregate mucus using a plurality of positively charged nanoparticles. There are also provided compositions and methods for inducing contraception in the subject.
    Type: Application
    Filed: February 2, 2011
    Publication date: August 4, 2011
    Inventors: Wei-Chun Chin, Eric Yi-Tong Chen
  • Publication number: 20110159103
    Abstract: Hydrophobic liquids are microencapsulated by an enteric matrix in an environment substantially free of organic solvents. The process includes forming an emulsion of the enteric material and hydrophobic liquid in water, titrating the emulsion with an acid to form a particulate precipitate and optionally coating the particulate with a combination of enteric material and plasticizer.
    Type: Application
    Filed: December 22, 2010
    Publication date: June 30, 2011
    Applicant: KRAFT FOODS GLOBAL BRANDS LLC
    Inventors: Ahmad Akashe, Anilkumar Ganapati Gaonkar, Les Lawrence, Amado R. Lopez, George W. Haas, Dana Sebesta, Yan Wang
  • Publication number: 20110150944
    Abstract: The present invention relates to structured triglycerides, to parenteral nutrition emulsions of the same, and uses thereof. In particular, the invention relates to structured triglycerides that include at least one medium chain C6-C12 fatty acid and at least one fatty acid selected from long chain C14-C18 or very long chain C20-C22 fatty acids. Preferably, each fatty acid is present in a predetermined position of the glycerol backbone. The parenteral nutrition emulsions are particularly useful for nourishing preterm- and term-infants, children, critically ill patients, and cancer patients.
    Type: Application
    Filed: March 2, 2011
    Publication date: June 23, 2011
    Inventors: Geila Rozen, Irit Shochat
  • Publication number: 20110135764
    Abstract: Embodiments of the invention relate to a composition for controlling a target pest, wherein the composition includes at least two active ingredients selected from the group consisting of thymyl acetate, linalyl acetate, amyl butyrate, anise star oil, black seed oil, p-cymene, geraniol, isopropyl myristate, d-limonene, linalool, lilac flower oil, methyl salicylate, alpha-pinene, piperonal, piperonyl alcohol, tetrahydrolinalool, thyme oil white, thyme oil red, thymol, vanillin, and winter-green oil, wherein the composition causes synergistic control of the target pest.
    Type: Application
    Filed: March 19, 2009
    Publication date: June 9, 2011
    Applicant: TyraTech, Inc.
    Inventor: Essam Enan
  • Publication number: 20110136906
    Abstract: Use of hydroxyoleic acid and its analogous compounds in the manufacture of drugs. Describes the use of hydroxyoleic acid and its analogs of general formula I: COOH—CHR—(CH2)m—CH?CH—(CH2)n—CH3, in which m and n have, independently, a value of 0-15 and R can be any residue with molecular weight below 200 Da, in the manufacture of drugs that can be used in the treatment of cancer, hypertension, obesity or diseases mediated by alteration of the membrane structure and the consequent regulation of G-proteins or of the receptors coupled to them.
    Type: Application
    Filed: November 4, 2010
    Publication date: June 9, 2011
    Inventor: Pablo Vicente ESCRIBA-RUIZ
  • Publication number: 20110130704
    Abstract: The present invention relates to a cosmetic method intended in particular to improve the appearance of the skin and/or hair comprising the simultaneous and/or sequential administration: a) of at least one compound bioconvertible by lipase; and b) of at least one light radiation exhibiting at least one predominant wavelength which activates lipase. In particular, the said light radiation according to the invention exhibits (emits) at least one predominant wavelength which activates lipase ranging from 400 to 510 nm, preferably from 430 to 500 nm, and is preferably used at a dose ranging from 0.01 to 200 J/cm2, preferably from 0.1 to 30 J/cm2, more preferably from 1 to 30 J/cm2, indeed even from 5 to 30 J/cm2.
    Type: Application
    Filed: February 25, 2009
    Publication date: June 2, 2011
    Applicant: L'OREAL
    Inventors: Francine Baldo, Quang Lan Nguyen, Dang-Man Pham
  • Publication number: 20110130456
    Abstract: A hair growth regulating agent containing, as an active ingredient, a compound represented by the following formula (I): [wherein R1 represents a substituted or unsubstituted, linear or branched C2 to C25 alkyl group; a group represented by the following formula (II): (wherein R1? represents a substituted or unsubstituted, linear or branched C2 to C20 alkylene group, or —(CH2)n-{O—(CH2)m}o-O—(CH2)p- in which each of n, m, o, and p is an integer from 1 to 6; X? represents —CO—NH—, —O—CO—O—, —NH—CO—, —CO—O—, —O—CO—, or —O—; Y? represents a substituted or unsubstituted C1 to C4 alkylene group; R2? represents a hydrogen atom or a C1 to C4 alkyl group; R3? represents a C1 to C4 alkyl group; and when R2? and R3? each represent a C1 to C4 alkyl group, the two alkyl groups may be identical to or different from each other); or a group represented by the following formula (III): (wherein R1?, X?, and Y? have the same meanings as defined above; R4?, R5?, and R6?, which may be identical to or different from one another,
    Type: Application
    Filed: August 4, 2009
    Publication date: June 2, 2011
    Applicant: Kao Corporation
    Inventors: Yasuto Suzuki, Naoko Morisaki, Michiyo Sasajima
  • Publication number: 20110112010
    Abstract: The invention features pharmaceutical formulations containing octanoic acid or a salt or ester thereof. The pharmaceutical formulations are useful for the treatment of involuntary tremors.
    Type: Application
    Filed: February 12, 2009
    Publication date: May 12, 2011
    Applicants: The Government of the United States of America, as represented by The National Institutes of Health, Ariston Pharmaceuticals
    Inventors: Mark Hallett, John A. McLane, Fatta B. Nahab
  • Publication number: 20110098229
    Abstract: Provided herein are methods of improving one or more symptoms of a dermatological condition in a patient. The methods comprise topically administering a topical composition to the patient comprising a branched chain amino acid, and an enzyme activator. Also provided are kits comprising the topical composition and optionally a topical steroid.
    Type: Application
    Filed: October 28, 2009
    Publication date: April 28, 2011
    Inventor: Harbhajan S. Paul
  • Publication number: 20110087192
    Abstract: Devices and methods are provided for transmucosal drug delivery. The transmucosal drug delivery device may include a housing configured for intralumenal deployment, such as intravaginally, into a human or animal subject; a drug-dispensing portion which contains at least one drug, the drug-dispensing portion being configured to dispense the drug from the housing by positive displacement; and a permeability enhancer-dispensing portion configured to release or generate a permeability enhancing substance to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the permeability enhancing substance.
    Type: Application
    Filed: October 8, 2009
    Publication date: April 14, 2011
    Applicant: PALO ALTO RESEARCH CENTER INCORPORATED
    Inventors: Scott Uhland, Eric Peeters, Hussain Fatakdawala
  • Publication number: 20110081418
    Abstract: An object of the present invention is to provide a transdermal absorption enhancer by which various active ingredients are transdermally absorbed. In accordance with a transdermal absorption enhancer of the present invention which effective ingredient is lyotropic liquid crystal which has been utilized as a basic material for pharmaceutical preparations for external application and for cosmetics, transdermal absorption of a macromolecular substance and a water-soluble substance was able to be improved.
    Type: Application
    Filed: September 7, 2010
    Publication date: April 7, 2011
    Applicants: JAPAN SCIENCE AND TECHNOLOGY AGENCY, NANOEGG RESEARCH LABORATORIES, INC.
    Inventors: Yoko Yamaguchi, Rie Igarashi
  • Publication number: 20110077301
    Abstract: Mixture of fatty acids, their derivatives, ester or methyl ester derivates thereof, which may be administered to non-human mammals by diffusion in to ambient air during at least seven consecutive days, with a rapid kinetic of diffusion during the first three days of administration.
    Type: Application
    Filed: May 29, 2009
    Publication date: March 31, 2011
    Applicant: CEVA SANTE ANIMALE SA
    Inventors: Benedicte Deminiere, Sandrine Lacoste, Marie-Laure Loubiere
  • Patent number: 7915311
    Abstract: Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. The BPI inducing agents include, for example, lipoxin compounds.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: March 29, 2011
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Charles N. Serhan, Sean P. Colgan
  • Publication number: 20110065791
    Abstract: The invention concerns a process for preparing particles, which particles contain one or more spaces in which a gas phase is present which comprises at least one active ingredient, in particular at least one aroma, flavor or precursor for an aroma or flavor, and which space or spaces are at least substantially surrounded by an enveloping phase which at ambient temperature is at least substantially solid and at least substantially impermeable to the active ingredient, comprising allowing the gaseous active ingredient to migrate from or through the enveloping phase into the space or spaces at a temperature at which the enveloping phase is permeable to the gaseous active ingredient; and then cooling the particles to a temperature at which the enveloping phase of the particles is at least substantially impermeable to the active ingredient in the particles.
    Type: Application
    Filed: February 25, 2009
    Publication date: March 17, 2011
    Inventors: Albert Thijs Poortinga, Paul Bastiaan van Seeventer, Mathijs Hendrikus Johannes Martens, Derrick Adriaan Johannes Kirpestein
  • Publication number: 20110052729
    Abstract: The invention relates to a pharmaceutical or nutraceutical composition comprising an alkalized organic substance selected from the group comprising proteins, carbohydrates, lipids, amino acids, vitamins, therapeutic agents and mixtures thereof. Such compositions are useful for treating a range of diseases and conditions. They also give rise to beneficial physiological effects such as, for example, increasing physical strength, muscle mass and endurance.
    Type: Application
    Filed: August 26, 2010
    Publication date: March 3, 2011
    Inventor: Jeffrey M. Golini
  • Publication number: 20110039928
    Abstract: An anti-inflammatory composition for treatment of inflamed joints. This composition includes an alkali buffered creatine and a cetylated fatty acid. The composition can be used for treating inflammation either by oral ingestion or by topical treatment.
    Type: Application
    Filed: August 12, 2010
    Publication date: February 17, 2011
    Inventor: Jeffrey M. Golini
  • Publication number: 20110034556
    Abstract: Human skin is treated for cosmetic purposes, in particular for the management of skin irritation and/or inflammation as well as inhibiting ageing effects, which result therefrom by using a topical cream containing at least one transglutaminase inhibitor such as putrescine.
    Type: Application
    Filed: November 27, 2008
    Publication date: February 10, 2011
    Inventor: Kenneth Nicholis Dolynchuk
  • Publication number: 20110028547
    Abstract: The present invention relates to a new use of capsiate or dihydrocapsiate, more particularly to a composition for preventing and treating inflammatory disease, angiogenesis-related disease and autoimmune disease or for suppressing immunity comprising capsiate, dihydrocapsiate or a pharmaceutically acceptable salt thereof as an effective ingredient. The composition and immunosuppressant of the present invention may be used for preventing and treating inflammatory disease, angiogenesis-related disease and autoimmune disease, and for suppressing immunity.
    Type: Application
    Filed: May 27, 2008
    Publication date: February 3, 2011
    Applicant: Catholic University Industry Academic Cooperation
    Inventors: Dong Heun Shin, Young Guen Kwon, Bo Jeong Pyun, Tae-Yoon Kim
  • Publication number: 20110028424
    Abstract: An oil-in-water microemulsion is provided, which includes, on the basis of its total weight, the following components of A) 55-95 wt % of a water phase; B) 0.1-20 wt % of an oil phase, wherein the oil phase comprises at least one oil/fat component containing polyoxypropylene chains; and C) 1-25 wt % of an oil-in-water nonionic emulsifier, wherein the emulsifier is selected from the following group of: hydrophilic nonionic surfactants with polyoxyethylene chains as hydrophilic groups, polyglycerol fatty acid esters, polyglycerol fatty alcohol ethers, sucrose fatty acid esters, and hydrocarbyl polyglycosides. The oil-in-water microemulsion carries a large amount of oil. In addition, the use of an oil/fat containing polyoxypropylene chains is disclosed for increasing the amount of oil carried in an oil-in-water microemulsion.
    Type: Application
    Filed: July 27, 2010
    Publication date: February 3, 2011
    Applicant: EVONIK GOLDSCHMIDT GMBH
    Inventors: Haizhou Zhang, Jiali Zou, Jingya Dai, Zhiheng Gao
  • Publication number: 20110020228
    Abstract: A method for the treatment of cancer involves delivering a surface active agent to an organism, where the surface active agent selectively partitions to and kills cancer cells as opposed to healthy cells. The surface active agent can be an ionic or a non-ionic surfactant with a HLB of less than 29 or a mixture of surface active agents with a HLB of less than 40, where the hydrophobic portion is a lesser fraction of the surface active agent than the hydrophilic portion. A fluorescence method of detecting and locating cancer cells in an organism involves delivering a surface active agent, where the surface active agent includes a fluorescence moiety that upon selective partitioning of the surface active agent to the cancer cells and irradiation by a radiation source to excite the fluorescence moiety, a fluorescence emission is observed permitting the detection and location of the cancerous tissue by local volumes of relatively high intensity emission.
    Type: Application
    Filed: February 2, 2009
    Publication date: January 27, 2011
    Applicant: University of Florida Resarch Foundation, Inc.
    Inventors: Brij M. Moudgil, Manoj Varshney, Stephen R. Grobmyer
  • Publication number: 20110010817
    Abstract: The present invention relates to articles of manufacture having a formulation distributed therein, wherein the formulation comprises an active agent which manifests a desirable property when released from the articles of manufacture. The present invention also relates to methods for manufacturing these articles of manufacture, to vehicles for applying the formulation to these articles of manufacture, and to perception indicators indicating the presence and the amount of formulation comprising an active agent applied to an article of manufacture.
    Type: Application
    Filed: August 13, 2010
    Publication date: January 20, 2011
    Applicant: BIOMOD COLLECTION INC.
    Inventors: Karine Théberge, Isabelle Goudreault, François Quirion, Gérald Perron