Abstract: Novel pharmaceutical solutions and particularly novel pharmaceutical solutions comprising dimethyl sulfoxide (DMSO).

Abstract: The invention concerns a composition, i.e., a multifunctional medically active agent for rational therapy of malignant (cancerous) diseases based on cause-and-effect relationship. The new composition according to the invention contains dimethylsulfoxide, DMSO, or sulfolan, preferably DMSO, in combination with a therapeutically effective amount of at least one cytostatic agent. The invention also concerns a method for treatment of malignant (cancerous) conditions in man comprising local or systemic administration thereto of an effective dosage of the composition according to the invention.The invention surprisingly provides a composition, as well as a method of treatment, allowing rational specific or selective carcinostatic-carcinocidic therapy. This therapy-form aims at the intracytoplasmic 3-dimensional cytoskeleton (differentiation organelle) that is specifically changed in the malignant cells, as well as at the targets responsible for karyokinesis and cytokinesis.

Abstract: Methylsulfonylmethane (CH.sub.3 SO.sub.2 CH.sub.3) administered orally is effective in ameliorating the symptoms of gastrointestinal upset, e.g., produced by the ingestion of aspirin and other pharmaceuticals, and of allergic reactions. Oral compositions containing a mixture of such a pharmaceutical and methylsulfonylmethane are useful in avoiding the gastrointestinal upset which otherwise occurs when ingesting the former.