Carbon To Carbon Unsaturated Patents (Class 514/739)
  • Patent number: 9955695
    Abstract: The present invention relates to a pediculicide/ovicide composition and method of use thereof. In particular, the present invention relates to a pediculicide/ovicide composition comprising a sesquiterpene alcohol and a suitable carrier.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: May 1, 2018
    Assignee: Wild Child
    Inventor: John Found
  • Patent number: 9814911
    Abstract: Linalool and other materials which are skin penetrating vasodilators or which can be made to have such properties are applied, either by themselves or in skin treatment compositions, to the skin of the head and especially the back of the neck to prevent or alleviate the effects of migraine headaches or applied to sore muscles or ligaments to aid in minimizing the soreness, or are applied to wrinkled and/or old looking skin on the face, neck, torso, or extremities, other than on the hands, to minimize wrinkles and/or improve the skin's appearance and/or are applied to the head to grow hair on the head or prevent hair loss.
    Type: Grant
    Filed: July 14, 2012
    Date of Patent: November 14, 2017
    Inventors: Robert Benson Aylor, Leigh Heather Makover
  • Patent number: 9737493
    Abstract: Some aspects of the invention include attenuating DNMT1 inhibitor activity in an animal comprising administering an antioxidant. Other aspects of the invention include methods comprising administering a composition comprising a DNMT1 inhibitor and an antioxidant. In some instances in the methods, the animal is undergoing a treatment for cancer. Additional aspects of the invention include compositions comprising a DNMT1 inhibitor and an antioxidant.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: August 22, 2017
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Francesca R. Salipur, Paula J. Bates, Elsa Merit Reyes-Reyes, Bo Xu, Gerald B. Hammond
  • Patent number: 9730901
    Abstract: The invention relates to the area of the chemical-pharmaceutical industry and medicine, in particular, to an agent for treatment of dependence on ethyl alcohol and/or drugs, treatment of psychosomatic and neurological complications in such patients; to pharmaceutical compositions containing this agent; and to treatment methods for psychosomatic and neurological complications with this agent. The aim of the invention is to develop a new pharmaceutical agent with minimal side effects. The proposed therapeutic substance, for treatment of addiction to ethanol and/or drugs, for treatment of psychosomatic and neurological complications in such patients, which is presented by polyprenols of formula (1) where n=8-20. Therapeutic composition for treatment of addiction to ethanol and/or drugs, for treatment of psychosomatic and neurological complications in patients is suggested, which includes an effective amount of polyprenols of formula (1) where n=8-20.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: August 15, 2017
    Inventors: Viktor Ivanovich Roschin, Vagif Sultanovich Sultanov
  • Patent number: 9622478
    Abstract: Embodiments of the invention relate to compositions for topical administration to dogs and cats comprising the active components dinotefuran and flumethrin, and methods for the treatment and prevention of flea and tick infestation comprising topical administration of such compositions.
    Type: Grant
    Filed: October 16, 2013
    Date of Patent: April 18, 2017
    Assignee: SOLANO S.P. LTD.
    Inventors: Amnon Vardi, Nimrod Vardi, Fabian Trumper
  • Publication number: 20150098910
    Abstract: In certain embodiments, the present invention relates to compounds, compositions, and methods for disrupting biofilms. In some embodiments, the compounds and compositions comprise unsaturated long chain alcohols and/or aldehydes, or combinations of such compounds. In further embodiments, the present invention contains therapeutic actives to help reduce and/or eradicate the bacteria in the biofilm once the film is disrupted.
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventors: Carolyn J. Mordas, Robert J. Gambogi
  • Patent number: 9000030
    Abstract: A method of inhibiting excitotoxicity by indirectly activating ?4?2 nicotinic acetylcholine receptors (nAChRs) which indirectly activate synaptic AMPA and NMDA receptors is disclosed Inhibitors of ?7 nACHRs, such as macrocyclic diterpenoids, more specifically cembranoids or methyllycaconitine (MLA), indirectly activate ?4?2 nAChRs and can be used to treat neurodegenerative diseases, including, but not limited to, Alzheimer's Disease, Parkinson Disease, AIDS related dementia and the delayed effects of stroke. They can also be used to treat diseases associated with neuronal impairment, including, but not limited to glaucoma caused by optical nerve damage, delayed effects of epilepsy; and multiple sclerosis.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: April 7, 2015
    Inventors: Peter Andrew Ferchmin, Vesna Ana Eterovic De Ferchmin, Hector Manuel Maldonado, Khalid El Sayed
  • Publication number: 20150093354
    Abstract: In various embodiments, the present disclosure provides a method and enzyme for forming various compounds, such as monoterpenes and monoterpenoid compounds. In a specific example, the present disclosure provides a method for producing one or more of (?)-ipsdienol, (?)-ipsenol, ipsenone, and ipsdienone. The present disclosure also provides methods of using compounds formed from the disclosed method and enzyme.
    Type: Application
    Filed: December 8, 2014
    Publication date: April 2, 2015
    Applicant: Board of Regents of the Nevada System of Higher Education, on Behalf of the University of Nevada
    Inventors: Claus Tittiger, Rubi Figueroa-Teran, Gary J. Blomquist
  • Patent number: 8987262
    Abstract: The present technology relates the use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas, for example of infantile hemangiomas. The beta blocker may be a non-selective beta-blocker, for example propranolol. The present technology provides an alternative to the known compounds, e.g. corticosteroïds, interferon or vincristine, generally used for the treatment of hemangiomas.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: March 24, 2015
    Assignees: Universite de Bordeaux, Centre Hospitalier Universitaire de Bordeaux
    Inventors: Christine Leaute-Labreze, Eric Dumas De La Roque, Alain Taieb, Jean-Benoit Thambo
  • Patent number: 8987263
    Abstract: Basic esters of fatty alcohols of the general formula: R1-O—CO-A or pharmaceutically acceptable salts thereof, wherein R1 is C12-C24 alkyl or C10-C24 alkenyl, and A is a residue containing at least one acyclic or cyclic amino group and/or at least one heteroaromatic ring containing a tertiary or quaternary nitrogen atom, are anti-inflammatory and immunomodulatory agents, useful in the treatment of immunologically-mediated inflammation, as adjuvants for antigens involved in both cellular and humoral responses.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: March 24, 2015
    Inventors: Meir Shinitzky, Irun R. Cohen, Raanan Margalit, Yaacov Herzig, Jeffrey Sterling, Gyorgy Toth, Istvan Miskolczi, Ferenc Rantal, Tivadar Tamas
  • Patent number: 8987338
    Abstract: The invention relates to an area of the chemical-pharmaceutical industry and medicine, particularly to an agent for treatment of dementias, including Alzheimer's disease (AD), as well as to a method of treatment and pharmaceutical composition, which is effective for both treatment of dementias, including AD or dementias of Alzheimer type, and during manifestations of the first symptoms of memory disorder. The given invention consists of the development of a new therapeutic substance with minimal side effects that currently is a topical issue for treatment of the corresponding diseases. Attached is the use of polyprenols of formula (1) where n=8-20 as an active ingredient for the production of the therapeutic agent for the treatment of patients with dementia syndrome, including those who suffer from Alzheimer's disease. It is proposed to use a therapeutic agent for the treatment of patients with dementia syndrome, including those suffering from Alzheimer's disease, being polyprenols of formula (1).
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: March 24, 2015
    Inventors: Viktor Ivanovich Roschin, Vagif Sultanovich Sultanov
  • Publication number: 20150072953
    Abstract: The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.
    Type: Application
    Filed: June 16, 2014
    Publication date: March 12, 2015
    Inventors: Lidia Alfaro Brownell, Min Chu, Mei-Feng Hong, Eu-Jin Hyun, Qi Jia, Ping Jiao, Hyun-Jin Kim, Mi-Ran Kim, Tae-Woo Kim, Bo-Su Lee, Young-Chul Lee, Breanna Moore, Jeong-Bum Nam, Mi-Sun Oh, Mi-Hye Park, Mesfin Yimam, Qian Zhang
  • Patent number: 8952074
    Abstract: The invention relates to the chemical and pharmaceutical industry and to medicine, in particular, to medicinal agents based on a mixture of natural oligomers of isoprenol (Ropren), which inhibits monoamine oxidase (MAO) activity; and to a method for treatment of patients suffering from diseases associated with the excessive activity of monoamine oxidase. The given invention consists of the development of a new therapeutic substance with minimal side effects that is currently a topical issue for treatment of the corresponding diseases. The proposed: Therapeutic substance consisted of polyprenols of formula (1) for treatment of patients with diseases associated with excessive activity of monoamine oxidase. with content of polyprenols of formula (1) in the given therapeutic substance from 0.1 to 80%.
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: February 10, 2015
    Inventors: Viktor Ivanovich Roschin, Vagif Sultanovich Sultanov
  • Publication number: 20150025077
    Abstract: This invention relates to geranylgeranyl acetone (GGA) derivatives and the use of GGA, its isomers, and GGA derivatives in methods for inhibiting neural death, increasing neural activity, increasing axon growth and cell viability, and increasing the survival rate of subjects administered the GGA or GGA derivatives.
    Type: Application
    Filed: February 27, 2013
    Publication date: January 22, 2015
    Applicant: COYOTE PHARMACEUTICALS, INC.
    Inventors: Hiroaki Serizawa, Ankush B. Argade, Akash Datwani, Natalie Spencer, Yonghua Pan, Florian Ermini
  • Patent number: 8912230
    Abstract: The invention relates to the use of a molecule selected from the group which consists of geranyl acetate, geraniol, isomenthone, limonene or a mixture of at least two of the above, for preparing a drug for treating or preventing vascular endothelial cell senescence and subjacent tissue degeneration induced by repeated inflammatory episodes. Specifically, the drug is useful for treating vascular endothelial cell senescence and tissue degeneration induced by repeated inflammatory episodes resulting from the presence of cancer cells.
    Type: Grant
    Filed: October 23, 2006
    Date of Patent: December 16, 2014
    Assignee: Aisa Therapeutics
    Inventor: Patrizia D'Alessio
  • Publication number: 20140348959
    Abstract: Compositions and methods for treatment of conditions such as ear pain are disclosed.
    Type: Application
    Filed: August 12, 2014
    Publication date: November 27, 2014
    Inventors: Mark A. Mitchnick, Garry Gwozdz
  • Patent number: 8883221
    Abstract: Micronutrient combination product, wherein the micronutrient combination product comprises zeaxanthin, lutein, zinc and copper.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: November 11, 2014
    Assignee: Bausch & Lomb Incorporated
    Inventors: Guenter Bellmann, Gudrun Claus-Herz
  • Publication number: 20140329911
    Abstract: Provided herein are methods for predicting efficacy of a DNA (cytosine-5)-methyltransferase 1 (DNMT1) inhibitor treatment in a subject having a cancer, methods of identifying a subject having a cancer that is more likely to respond to a DNMT1 inhibitor treatment, and methods of selecting a treatment for a subject having a cancer that include determining a level of SOX9 in a sample containing cells from a subject having a cancer. Also provided are methods of treating a subject having a cancer that include selectively administering a DNMT1 inhibitor to a subject having cancer determined to have an elevated level of SOX9 in a sample containing cells from the subject compared to a reference level. Also provided are antibodies and antigen-binding antibody fragments that specifically bind to SOX9, and nucleic acid sequences that contain at least 10 nucleotides complementary to a contiguous sequence present in a SOX9 nucleic acid for use in these methods.
    Type: Application
    Filed: March 7, 2012
    Publication date: November 6, 2014
    Applicant: University of Louisville Research Foundation, Inc.
    Inventors: Paula J. Bates, Mohammad Tariq Malik, Francesca R. Salipur
  • Publication number: 20140302146
    Abstract: The present invention provides an ophthalmic aqueous composition having an oil-in-water emulsion including a vegetable oil, a non-ionic surfactant, and a terpenoid, wherein an average particle diameter of emulsion particles is within the range of 30 nm to 300 nm.
    Type: Application
    Filed: July 5, 2012
    Publication date: October 9, 2014
    Applicant: ROHTO PHARMACEUTICAL CO.,LTD.
    Inventors: Takahiro Kurose, Takayuki Miyano, Toru Okubo, Mariyo Kato
  • Patent number: 8853272
    Abstract: A method for treating an inflammation or lesion caused by herpes virus, comprising topically applying to said inflammation or lesion a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C2 to C4 diol and a sufficient amount of an acid to adjust the pH of the composition to below 4.6. Topical administration of the composition is preferred and is effective in treating lesions associated infections by viruses such as Herpes simplex. Nasal deliverable forms are effective in treating symptoms due to viruses that cause the common cold. Pharmaceutical compositions for use in the present method are provided.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: October 7, 2014
    Assignee: Topical Remedy, LLC
    Inventors: Thomas W. Konowalchuk, Jack Konowalchuk
  • Publication number: 20140296348
    Abstract: The present invention provides an aqueous ophthalmic composition having a pH of 7 or more, containing a terpenoid and zinc chloride. According to the present invention, an aqueous ophthalmic composition is provided in which adsorption of the terpenoid to a container can be inhibited, thereby making it possible to inhibit the reduction in the terpenoid content for a long period of time, the aqueous ophthalmic composition having some excellent actions such as an inhibitory action for histamine release, and an inhibitory action for discharges from the eyes.
    Type: Application
    Filed: October 31, 2012
    Publication date: October 2, 2014
    Inventors: Yasuko Matsumura, Chinatsu Furumiya, Masashi Itoh
  • Publication number: 20140274683
    Abstract: Compositions including (a) a pollinating insect repelling, controlling, or directing compound or composition and (b) a compound or composition capable of protecting seeds, plant parts, or plants against insect and/or nematode infestation are provided. The disclosure also provides for methods of repelling, controlling, or directing a pollinating insect, for example a bee, while protecting seeds, plant parts, and/or plants against insect and/or nematode infestation. Seeds, plants, and plant parts treated with compositions described herein are also provided for by the disclosure.
    Type: Application
    Filed: March 5, 2014
    Publication date: September 18, 2014
    Applicant: Bayer CropScience LP
    Inventors: Tai-Teh WU, Dick ROGERS, Jian ZHANG, Robert CROFT, Chi Yu Roy CHEN
  • Publication number: 20140259191
    Abstract: This invention relates to a method of sedating, anaesthetising or euthanising an aquatic organism comprising the step of contacting said organism with linalool, a compositions, a body of water containing thereof and a method of transporting an aquatic organism.
    Type: Application
    Filed: August 22, 2012
    Publication date: September 11, 2014
    Applicant: AQUA-MOR TECHNOLOGIES LTD.
    Inventor: Dani Neifeld
  • Publication number: 20140228448
    Abstract: The present invention relates to the use of R—OH alcohols as phagodeterrents, and to a method for treating plants infested with aphids which comprises the administration of these R—OH alcohols.
    Type: Application
    Filed: May 14, 2012
    Publication date: August 14, 2014
    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Maria Agnese Sabatini, Sonia Ganassi, Claudio Altomare, Mara Favilla, Antonio Evidente, Anna Andolfi
  • Patent number: 8795699
    Abstract: A method of repelling wasps, which method comprises using a preparation comprising (a) one or more of ethyl 3-(N-n-butyl-N-acetylamino)propionate, dihydronepetalactone, and extract of catmint, and (b) at least one compound selected from certain perfume ingredients. This abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: August 5, 2014
    Assignee: Beiersdorf AG
    Inventors: Rainer Kroepke, Jens Schulz, Jens Nielsen, Stephanie Von Der Fecht
  • Patent number: 8765819
    Abstract: The present invention relates to the use of low content of benzoic acid and/or sodium salt thereof in combination with one or more organic acid preservatives as active ingredients in the manufacture of a vaginal composition, wherein the composition has weak inhibition effect on normal vaginal lactobacilli while has strong inhibition effect on vaginal fungi and/or pathogenic vaginal lactobacilli, the organic acid preservatives are selected from the group consisting of dehydroacetic acid and/or sodium salt thereof, propionic acid and/or a salt thereof, sorbic acid and/or a salt thereof. The composition of the present invention is particularly useful in inhibiting vaginal fungi, and/or inhibiting pathogenic vaginal lactobacilli, and/or promoting normal vaginal lactobacilli, and/or maintaining normal vaginal acidity, and/or modulating vaginal microecosystem, and/or modulating vaginal microbials, and/or selectively decontaminating vagina.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: July 1, 2014
    Inventors: Zhongming Zeng, Ruyun Zhou
  • Patent number: 8758787
    Abstract: An insect repellent material includes a carrier such as a polyethylene, a molecular sieve or zeolite material, and a repellent such as geraniol. The molecular sieve/zeolite material provides the insect repellent material with a slow-release quality and also permits the carrier to hold more insect repellent than it would otherwise if so desired.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: June 24, 2014
    Assignee: Fasst Products, LLC.
    Inventors: Herman L. Friend, E. Cole Nelson, Jr.
  • Patent number: 8703829
    Abstract: The invention provides compounds of Formula (I): R1?R2??(I) wherein R1 and R2 have any of the values or specific values defined herein, as well as compositions comprising such compounds and therapeutic methods comprising the administration of such compounds.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: April 22, 2014
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Gerald B. Hammond, Bo Xu, Paula J. Bates
  • Patent number: 8697043
    Abstract: Disclosed are odor suppressing analgesic compositions comprising: a) from about 0.1% to about 20%, by weight, of farnesol or other suitable deodorizing bacteriostatic agent; and b) from about 0.1% to about 60%, by weight, volatile organic compound wherein said volatile organic compound may be encapsulated and is chosen from the following (menthol, camphor, methyl salicylate, methyl nicotiniate, or combination of thereof); and c) a water-in-oil or oil-in-water emulsion, gel, patch, plaster, ointment, solution or spray carrier. An optimized odor suppressing analgesic composition can provide a combination of antimicrobial properties, odor suppression properties, skin cooling or heating properties, topical analgesic properties, low irritation and stability.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: April 15, 2014
    Assignee: Chattem, Inc.
    Inventors: Vardan Ter-Antonyan, Jason Sondgeroth, David Jaeger, Shane Smith, Elisa Barnes
  • Patent number: 8691256
    Abstract: Embodiments of the present invention provide compositions for controlling a target pest including a first agent and a second agent comprising a pest control product or a signal cascade modulator, wherein the first agent and the second agent act synergistically to control the target pest. The first agent can be capable of interacting with a receptor in the target pest. The pest control product can have a first activity against the target pest when applied without the active agent and the compositions can have a second activity against the target pest; and the second activity can be greater than the first activity. Embodiments of the invention can include compositions that modulate the signal cascade initiated by the binding of ligands to, for example, cell surface receptors. Methods of screening such compositions are also disclosed.
    Type: Grant
    Filed: March 19, 2009
    Date of Patent: April 8, 2014
    Assignee: Tyratech, Inc.
    Inventor: Essam Enan
  • Publication number: 20140088185
    Abstract: A buccally administered dosage for assisting with the relief of common digestive complaints where the dosage formed into a hard candy dosage drop, where the dosage is a sugar base infused with a botanical derivative that has concentrated active compositions in sufficient concentration to provide a soothing effect of digestive upset, and where the drop has favorable organoleptic properties.
    Type: Application
    Filed: November 27, 2013
    Publication date: March 27, 2014
    Inventors: Dustin Garth James, Helen Kim-James
  • Publication number: 20140080919
    Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.
    Type: Application
    Filed: November 20, 2013
    Publication date: March 20, 2014
    Applicant: ECOLAB USA INC.
    Inventors: Joseph R. Wegner, Cheryl A. Littau
  • Publication number: 20140073703
    Abstract: Phytol (3,7,11,15-Tetramethyl-2-hexadecen-1-ol),orderivates thereof, of natural or synthetic origin are used as active ingredient in formulations to lower serum levels of triglycerides and/or cholesterol. Phytol can be administered to patients with disease conditions related to increased levels of cholesterol or triglycerides such as type II diabetes, obesity or other patients in risk of cardiovascular diseases due to elevated cholesterol levels. Phytol can also be administered to healthy individuals to maintain normal levels of serum cholesterol.
    Type: Application
    Filed: December 26, 2012
    Publication date: March 13, 2014
    Inventors: Peter Olofsson, Malin Hultqvist, Rikard Holmdahl
  • Publication number: 20140024603
    Abstract: New fibroblast growth factor receptor 1 (FGFR1) inhibitors have been identified which are useful for promoting the retention and/or growth of keratin fibers, such as hair of the scalp, hair of the face (moustache, beard, etc.), eyebrows, eyelashes, and the like. The FGFR1 inhibitors may be formulated in effective amounts in a variety of cosmetic and personal care products.
    Type: Application
    Filed: September 25, 2013
    Publication date: January 23, 2014
    Applicant: Avon Products, Inc.
    Inventors: Michele C. Duggan, Satish Parimoo, Cheng S. Hwang
  • Patent number: 8632795
    Abstract: The present invention relates to a device in the form of a container made of a polymer material, which container has one or more sealed chambers, each of which comprise a liquid pheromone comprising 2-ethyl-1,6-dioxaspiro[4,4]nonane, methyl 2,4-decadiene-carboxylate and at least one alcohol selected among 2-methylbut-3-en-2-ol and 2-methylbut-3-yn-2-ol, where at least 50% of the area of the walls forming the chambers have a wall thickness in the range of from 0.1 to 1 mm and the polymer material which forms the chamber is at least in those areas an uncoated vinyl acetate/ethylene copolymer with a vinyl acetate content in the range of from 10 to 17% by weight. The invention also relates to a method of combating and for monitoring the swarming behavior of the species Pityogenes chalcographus, generally also referred to as spruce wood engraver or six-dentated bark beetle.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: January 21, 2014
    Assignee: BASF SE
    Inventors: Thomas Zühlke, Jürgen Jentzsch, Ulf Baier, Hansjochen Schroeter
  • Publication number: 20130331422
    Abstract: The present invention provides for a method of treating a disease such as cancer, comprising the step of administering to a patient a therapeutically effective amount of an isomer or analog of monoterpene or sesquiterpene (or its derivative), such as an isoperillyl alcohol. The present invention also provides for a method of treating a disease comprising the step of administering to a patient a therapeutically effective amount of a derivative of an isomer or analog of monoterpene or sesquiterpene, such as an isoperillyl alcohol carbamate. The derivative may be an isoperillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The route of administration may vary, including inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection.
    Type: Application
    Filed: December 16, 2011
    Publication date: December 12, 2013
    Applicant: NEONC Technologies Inc.
    Inventors: Thomas Chen, Daniel Levin, Satish Puppali, Daniel Anthony Dickman
  • Publication number: 20130324613
    Abstract: Psoriasis is a common, chronic, inflammatory skin disorder. This invention provides the use of a compound of formula (I) R—CO—X (Wherein R is a C16-24 unsaturated hydrocarbon group optionally interrupted by ?, ?, ?, or ? to the carbonyl group by a heteroatom or group of heteroatoms selected from S, O, N, SO, SO2 said hydrocarbon group comprising at least 5 non-conjugated double bonds; and X is an electron withdrawing group) in the manufacture of a medicament for the treatment of psoriasis.
    Type: Application
    Filed: August 2, 2013
    Publication date: December 5, 2013
    Applicant: Avexxin AS
    Inventors: Berit Johansen, Marit Anthonsen, Wenche Sjursen, Anne Kristen Holmeide, Lars Skattebol
  • Publication number: 20130261191
    Abstract: Essential oil compounds, such as p-cymene, thymol, salicylaldehyde, tea tree oil, peppermint oil, cuminaldehyde, cinnamic acid, cinnamic alcohol, farnesal and farnesylacetone, especially 2-decenal and nerolidol when added to feed or drinking water to combat histomonas, a single cell protozoan organism that is an intestinal parasite infecting both vertebrates and invertebrates.
    Type: Application
    Filed: May 16, 2013
    Publication date: October 3, 2013
    Applicant: DSM IP ASSETS B.V.
    Inventors: Marco FREHNER, Riccardo Losa, Didier Archain
  • Patent number: 8529928
    Abstract: Biodegradable polymers incorporating biomolecules and methods of their use are provided. Certain aspects provide biomolecules crosslinked with diglycidyl esters. The disclosed compositions have numerous applications including cellular regeneration, wound healing, and cellular differentiation.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: September 10, 2013
    Assignee: Georgia Tech Research Corporation
    Inventors: Yadong Wang, Blaine Zern, Christiane Gumera
  • Patent number: 8512723
    Abstract: Antimicrobial compositions, especially those useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes), including, in particular, an antimicrobial lipid component, such as a fatty acid ester, fatty ether, or alkoxide derivative thereof. The compositions can also include an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component. Such compositions provide effective topical antimicrobial activity and are accordingly useful in the treatment and/or prevention of conditions that are caused, or aggravated by, microorganisms (including viruses).
    Type: Grant
    Filed: September 8, 2004
    Date of Patent: August 20, 2013
    Assignee: 3M Innovative Properties Company
    Inventors: Matthew T. Scholz, Dianne L. Gibbs, John T. Capecchi, Jeffrey F. Andrews
  • Publication number: 20130165495
    Abstract: A method of inhibiting excitotoxicity by indirectly activating ?4?2 nicotinic acetylcholine receptors (nAChRs) which indirectly activate synaptic AMPA and NMDA receptors is disclosed Inhibitors of ?7 nACHRs, such as macrocyclic diterpenoids, more specifically cembranoids or methyllycaconitine (MLA), indirectly activate ?4?2 nAChRs and can be used to treat neurodegenerative diseases, including, but not limited to, Alzheimer's Disease, Parkinson Disease, AIDS related dementia and the delayed effects of stroke. They can also be used to treat diseases associated with neuronal impairment, including, but not limited to glaucoma caused by optical nerve damage, delayed effects of epilepsy; and multiple sclerosis.
    Type: Application
    Filed: November 9, 2012
    Publication date: June 27, 2013
    Inventors: Peter Andrew Ferchmin, Vesna Ana Eterovic De Ferchmin, Hector Manuel Maldonado, Khalid El Sayed
  • Publication number: 20130156839
    Abstract: The present invention provides compositions and methods for the control and management of wildlife populations (including domesticated animals) and pests such as birds including geese, deer and other herbivore such as rabbits, ground hogs, raccoons, moose and elk, tunneling animals such as moles, voles and gophers and insects, carnivores and other organisms. Specifically provided are geraniol oil-based formulations which may be applied to natural or artificial surfaces. Also provided are pest control systems incorporating the use of repellent or attractant formulations.
    Type: Application
    Filed: April 11, 2011
    Publication date: June 20, 2013
    Inventors: James J. Messina, James D. Messina
  • Publication number: 20130149399
    Abstract: An object of the present invention is to provide a skin temperature elevating agent that can further effectively raise a skin temperature. Another object is to provide a cosmetic composition, a food and a sundry article having a skin temperature elevating effect. A skin temperature elevating agent of the present invention is selected from one or more selected from a group consisting of: an extract of Japanese peppermint; an extract of clary sage; dihydro-?-ionol; and geraniol, and thus it can raise a skin temperature of a cheek. The skin temperature elevating agent according to the present invention is also selected from one or more selected from a group consisting of: an extract of Japanese peppermint; an extract of juniper berry; and 4-methoxystyrene, and thus it can raise a skin temperature of a hand fingertip. Hence, the skin temperature elevating agent according to the present invention can further effectively raise a skin temperature.
    Type: Application
    Filed: May 26, 2011
    Publication date: June 13, 2013
    Inventors: Keiko Mori, Shinichiro Haze, Yoko Gozu, Atsushi Joichi
  • Publication number: 20130150443
    Abstract: The present invention relates to a novel use of compounds having the general formula (I): CH3(—CH?CH)n—R??(I) where n=from 2 to 7, and R is chosen from among: CHO, CH2OH, CH2O—CO—R?, CO—OR?, CO—O(-), where R? is chosen from among H, the alkyl from C1 to C22, each compound of general formula (I) being used as such or in a mixture, as an active principle in a pharmaceutical or cosmetic composition to improve the human epidermal cell repair activity by means of the production of keratin mediated by the cytokeratins cK-19.
    Type: Application
    Filed: February 6, 2013
    Publication date: June 13, 2013
    Applicant: GIULIANI S.P.A.
    Inventors: Giammaria GIULIANI, Anna BENEDUSI, Sergio BARONI
  • Publication number: 20130101687
    Abstract: Insecticidal compositions have at least one active agent and at least one insecticide. The active agent can include perilla oil, a component found in perilla oil, or a perillaldehyde or carvone analog. The insecticide can include a pyrethrum, pyrethrin, pyrethroid, neonicotinoid, chlofenapyr, ethiprole, sulfoxoflor, carbamate, organophosphate, or organochlorine. Methods for controlling insects include contacting an insect with an effective amount of a composition described in this specification. Modified plants that produce an active agent can be contacted with an insecticide.
    Type: Application
    Filed: July 13, 2012
    Publication date: April 25, 2013
    Inventors: Michael Dean Willis, Marie Elizabeth Saunders, Darryl Ramoutar, Joanna Maria Szymczyk, Frances Nita Krenick, Andrea Rohrbacher
  • Publication number: 20130059921
    Abstract: The present invention concerns various compositions comprising the essential oil of Origanum compactum or of Aniba rosaeodora or one of their constituents, preferably a major constituent, for use in the targeted treatment and prevention of keratoses in the transformation phase and of carcinomas originating from these keratoses, and more particularly of keratoses induced by solar radiation on the skin of a subject. More particularly, the present invention concerns compositions based on the essential oil of oregano or of rosewood, or on linalool, thymol or carvacrol.
    Type: Application
    Filed: February 28, 2011
    Publication date: March 7, 2013
    Applicants: L'Oreal, Centre National De La Recherche Scientifique, Institut Curie
    Inventors: Laurent Marrot, Jérémie Soeur, Meng-Er Huang
  • Publication number: 20130058878
    Abstract: Geranylgeranyl-2-propanol compound (GGP) having the following formula (I) is proposed for use according to the present invention as a cosmetic active compound for the prevention and treatment of aging of skin and its appendages. The GGP has a protective action against oxidative stress and free radical, on telomeres and on mitochondria and its activity. In particular, GGP can be used for the treatment of wrinkles, fine lines and visible discontinuities of skin, for the treatment pigmentation disorders.
    Type: Application
    Filed: April 7, 2011
    Publication date: March 7, 2013
    Applicant: SEDERMA
    Inventors: Arnaud Fournial, Philippe Mondon, Olivier Peschard
  • Patent number: 8388949
    Abstract: The invention relates to the field of food compositions and their use. In particular compositions comprising at least 15 En % protein and pantothenic acid, or equivalents thereof, are provided, which are suitable for stimulating appetite.
    Type: Grant
    Filed: December 24, 2004
    Date of Patent: March 5, 2013
    Assignee: N.V. Nutricia
    Inventor: Robert Johan Joseph Hageman
  • Patent number: 8362077
    Abstract: The present invention provides preservative compositions suitable for replacing, partially or in totality, conventional preservatives in skin care emulsions and heavy duty hand cleansers comprised of alternative molecular compounds than found in conventional preservative formulations. The preservative formulation for skin care formulations includes a fatty acid and/or ester of fatty acid present in a concentration from about 0.01 wt./wt. % to about 90 wt./wt. % of the formulation, one or more alcohols in a concentration from about 0.01 to about 60 wt./wt. % of the formulation, and a chelating agent present in a concentration from about 0.01 to about 20 wt./wt. % of the blend.
    Type: Grant
    Filed: August 15, 2008
    Date of Patent: January 29, 2013
    Assignee: Pibed Limited
    Inventors: Pierre Bruno Grascha, Mylene Battut
  • Publication number: 20130018109
    Abstract: Linalool and other materials which are skin penetrating vasodilators or which can be made to have such properties are applied, either by themselves or in skin treatment compositions, to the skin of the head and especially the back of the neck to prevent or alleviate the effects of migraine headaches or applied to sore muscles or ligaments to aid in minimizing the soreness, or are applied to wrinkled and/or old looking skin on the face, neck, torso, or extremities, other than on the hands, to minimize wrinkles and/or improve the skin's appearance and/or are applied to the head to grow hair on the head or prevent hair loss.
    Type: Application
    Filed: July 14, 2012
    Publication date: January 17, 2013
    Inventors: Robert Benson Aylor, Leigh Heather Makover