Abstract: This application provides a method for the use of select quaternary ammonium antagonists to alpha-7 nAChR for the treatment of cancer and HIV and AIDS.
Type:
Application
Filed:
October 13, 2009
Publication date:
July 15, 2010
Applicant:
University of Kentucky Research Foundation
Inventors:
Roger L. PAPKE, Peter A. CROOKS, Linda P. DWOSKIN, Gretchen Lopez HERNANDEZ, Zhenfa ZHANG, Jeffrey S. THINSCHMIDT, Guangrong ZHENG
Abstract: The present invention provides pH-sensitive micro-capsules, compositions containing them, methods for their preparation and methods for their use.
Type:
Grant
Filed:
August 13, 1999
Date of Patent:
December 31, 2002
Assignee:
BASF Aktiengesellschaft
Inventors:
Robin William Dexter, Brian Eric Benoff
Abstract: One can impart outstanding resistance against collapse under pressure to gas-filled microvesicle used as contrast agents in ultrasonic echography by using as fillers gases whose solubility in water, expressed in liter of gas by liter of water under standard conditions, divided by the square root of the molecular weight does not exceed 0.003.
Abstract: A method for the acceleration of tissue growth using continuous fluorocarbon liquid-based positive pressure is disclosed, whereby significant increase in tissue growth is achieved.
Abstract: One can impart outstanding resistance against collapse under pressure to gas-filled microvesicle used as contrast agents in ultrasonic echography by using as fillers gases whose solubility in water, expressed in liter of gas by liter of water under standard conditions, divided by the square root of the molecular weight does not exceed 0.003.
Abstract: Disclosed herein are agents for enhancing the contrast in an ultrasound image. These agents are extremely small bubbles, or "microbubbles," comprised of specially selected gases. The microbubbles described herein exhibit long life spans in solution and may be produced at a size small enough to traverse the lungs, thus enabling improved ultrasound imaging of the cardiovascular system and other vital organs. Also disclosed herein is a method for selecting gases from which contrast agents may be produced. The method is based on calculations using inherent physical properties of gases and describes a means to associate the properties of a gas with the time for dissolution of a microbubble comprised of the gas.
Abstract: Disclosed herein are agents for enhancing the contrast in an ultrasound image. These agents are extremely small bubbles, or "microbubbles," comprised of specially selected gases. The microbubbles described herein exhibit long life spans in solution and may be produced at a size small enough to traverse the lungs, thus enabling improved ultrasound imaging of the cardiovascular system and other vital organs. Also disclosed herein is a method for selecting gases from which contrast agents may be produced. The method is based on calculations using inherent physical properties of gases and describes a means to associate the properties of a gas with the time for dissolution of a microbubble comprised of the gas.
Abstract: Novel diarylacetylenes of the formula I ##STR1## where A, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 have the meanings stated in the description, are useful for the treatment of disorders.
Type:
Grant
Filed:
August 20, 1990
Date of Patent:
June 30, 1992
Assignee:
BASF Akteingesellschaft
Inventors:
Hans-Heiner Wuest, Fritz-Frieder Frickel, Axel Nuerrenbach