Abstract: The present invention relates to shark cartilage extracts and to a method of producing the same, these extracts having anti-angiogenic properties (reduction of the area of blood vessels observed in vivo on experimentally induced tumors), tumor regressive activity in vivo as well as demonstrating a direct inhibitory effect on tumor cell lines. This process does not involve any denaturing solvent or product and does not involve the use of any enzymes. It consists of obtaining a blend of whole cartilage in an aqueous solution of neutral pH, preferably pure water, this blend being centrifuged and the pellet and supernatant kept for further processing. The pellet is lyophilized and tested for anti-tumor and anti-angiogenic activities in vivo and in vitro, with or without supernatant. The supernatant has been shown to have anti-angiogenic and tumor regressive activities in vivo. The composition of the supernatant has then been investigated by different ways.

Abstract: The method of skin care includes applying a skin care preparation to the skin of an individual in an amount sufficient to moisturize the skin or to cause a reduction of skin wrinkling and a smoothing of the skin. The skin care preparation has a pH value of 1 to 7 and contains from 0.1 to 20 percent by weight of at least one betaine ester of formula (I)R.sub.1 --O--CO--CH.sub.2 --N.sup.+ (CH.sub.3).sub.3 A.sup.-(I),wherein R.sub.1 is a branched or straight chain alkyl group having from 10 to 30 carbon atoms and A- is a cosmetically acceptable anion; andfrom 0.05 to 20 percent by weight of at least one .alpha.-hydroxy acid present as a free acid, or in a lactone form thereof, or as a skin-compatible salt thereof with an organic base or an inorganic alkali, and/or as stereoisomers thereof, as D, L, and/or DL form. The at least one .alpha.-hydroxy acid is selected from the group consisting of alkyl .alpha.-hydroxy acids, aralkyl .alpha.-hydroxy acids, aryl .alpha.-hydroxy acids, polyhydroxy .alpha.

Abstract: A non-stinging styptic composition in the form of a water soluble resin coated cast pencil, for stopping bleeding from cuts and nicks received during shaving. The composition comprises aluminum sulfate, aloe, glycerine, lidocaine and polyethylene glycol 400.

Abstract: Compositions containing hydroxy acids and/or retinoids and further containing Trichodesma lanicum seed extract as an anti-irritant/anti-sting agent.

Abstract: A method of increasing the bulk density and improving the water-dispersibility, oil sorption capacity, and body dirt and oil removability by compacting and/or shearing a magnesium rich calcium montmorillonite clay. In an optional embodiment of the present invention, silica gel, sodium silicate, acrylic polymers and copolymers, carboxy methyl cellulose, or other materials capable of providing lubricity to the surface of the clay crystals is added to the clay, prior to shearing, to enhance the compaction and/or shearing process and further increase the bulk density of the clay. The clay is sheared in an extruder, pug mill or California-type pellet mill when the clay includes about 20% to about 45%, preferably about 25% to about 40% by weight water, based on the dry weight of the clay.

Abstract: A method and medicant for the inhibition of activation of the nuclear transcription NF-.kappa.B comprising administering an effective amount of a compound of the formula: ##STR1## where R=ethylene, R'=C.sub.4 to C.sub.14 straight chain or branched alkyl, x is greater than 1, and y=8 to 18 is provided. The medicant is preferably administered by aerosolization into the mammalian respiratory system. The medicant may also be applied to the mammalian skin. Preferably the medicant includes a physiologically acceptable carrier which may be selected from buffered saline, isotonic saline, normal saline, petroleum-based ointments and U.S.P. cold cream. There is further provided a method wherein said medicant includes an anti-inflammatory steroid. In addition a method and medicant for treating cutaneous inflammatory disorders, inhibiting the secretion of the pro-inflammatory cytokines TNF, IL-1, IL-6, IL-8 and the growth factor GM-CSF is provided.

Abstract: The use of ginsenoside R.sub.0 or a plant extract containing same to prepare a cosmetic or pharmaceutical composition, particularly a skin care composition, for promoting collagen synthesis, particularly collagen I and/or collagen III synthesis. Said cosmetic or pharmaceutical composition is administered to a mammal, particularly a human being, in order to promote collagen synthesis. A method for promoting collagen synthesis in fibroblast growth media is also disclosed.

Abstract: The present invention relates to the use of phosphate esters for the improvement of water solubility of salicylic acid and stability of peroxide compounds in an aqueous cleanser.

Abstract: A composition and method are described for the treatment of allergic contact dermatitis, such as poison ivy, poison oak, and poison sumac. The composition includes linseed oil, an astringent such as alum powder, a starch such as cornstarch, an essential oil such as eucalyptus oil, and a citrus oil such as orange oil. The method includes applying the treatment composition to an affected area of skin, preferably once to twice per day.

Abstract: The invention concerns a composition containing ingredients of the herb of the equisetum species and ingredients of the herb and/or of the flower of the lavandula species and used in the external prevention and control of dermatomycoses, in particular dermatophytoses, of skin ailments with the clinical appearance of tinea pedis and skin ailments caused by their pathogens at other body locations. The invention further relates to a composition as described above for the treatment and control of bromidrosis, other perspiration and unpleasant body odor, and to control dermatomycosis pathogens and pathogens able to cause the clinical appearance of tinea pedis in textiles, other wear and sanitary articles in contact with the skin, and to deodorize same, and to methods to achieve these effects and a method to prepare the composition of the invention.

Abstract: Novel pharmaceutically/cosmetically-active adamantyl-substituted polycyclic acetylene compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formulae (a)-(f): ##STR2## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular, bone and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Abstract: Aqueous dispersions of polymers which have a high glass transition temperature and a low average molecular weight and contain a specific amount of methacrylic acid as polymerized units are suitable, in liquid or dried form, as additives for improving the flow behavior of cement-containing mineral building materials having binding properties.

Abstract: An isopropyl alcohol gel having use as a rubbing composition and having antiseptic properties. The isopropyl alcohol gel of the present invention comprises a polymer, water, isopropyl alcohol and a polymer neutralizing agent. The polymer is dispersed in water to create a thick phase. The preferred polymer is a carbomer resin that forms a slightly gelatinous mass through hydration of the polymer. The selected amount of isopropyl alcohol is added by dispersion to the polymer-water phase. The mixture is allowed enough time to fully hydrate. A neutralizing agent is thereafter added to neutralize the activity of the polymer. The neutralizing agent is preferably tetrahydroxypropyl ethylenediamine. The resulting product is in homogenous heavy clear gel form.

Abstract: A method and medicament for the inhibition of oxidants comprising administering a treatment effective amount of alkylaryl polyether alcohol polymers to a chemical or biologic system in need thereof. The medicament is preferably administered by aerosolization into the mammalian respiratory system. The medicament may also be applied to the mammalian skin. Preferably, the medicament includes a physiologically acceptable carrier which may be selected from the group consisting of physiologically buffered saline, isotonic saline, normal saline, petrolatum based ointments and U.S.P. cold cream.

Abstract: A method of treating skin or hair for promoting pigmentation wherein a xanthine component, in an amount effective to promote pigmentation, is incorporated in liposomes or hydrated lipidic lamellar phases.

Abstract: A topical agent and method for the treatment and prevention of pseudofolliculitis barbae, related secondary bacterial infections and other skin conditions associated with shaving result from a combination of three ingredients, namely benzoyl peroxide, camphor oil and aloe vera present in 15:4:1 parts by volume of the composition, respectively.

Abstract: An anti-peroxide external preparation for skin comprising: decomposition product of shell membrane: and tocopherol and/or derivatives thereof. It is possible to suppress formation of peroxide and remove it.

Abstract: Solution comprising a mixture of aluminum acetate topical solution and glycerin useful as a skin moisturizer and/or a food particulate repellant for preventing chewed food particles from sticking to the teeth. When combined with a flavoring agent, the solution of aluminum acetate topical solution and glycerin is also effective as a saliva substitute for relieving the symptoms of xerostomia or "dry mouth syndrome.

Abstract: A method is provided for improving skin condition through a system whose steps include applying to the skin separately on a plurality of days a first composition that incorporates a retinoid which is either retinol or retinoic acid in a pharmaceutically acceptable carrier. Once the skin has acclimated to any irritation induced by the first composition, a second composition is applied to the skin daily for a subsequent period of time. The second composition will also include retinoid but at a level at least about 10% higher than that employed in the first composition. Once the skin has acclimated to the second composition, subsequent progressive increases of the active retinoid can be applied over subsequent periods of time. Finally, a maintenance level composition is utilized with the highest level of retinoid in the progressive program to minimize potential irritation.

Abstract: A therapeutic preparation for topical application to the skin for treating skin disorders such as minor burns, abrasions and the like, which contains myrrh oil.

Abstract: The instant invention is directed to a process for enhancing the efficacy of alcohol-based skin antiseptics comprising adding at least one alcohol-soluble viscosifying agent to an alcohol-based disinfectant, thereby lowering its alcohol evaporation rate and markedly increasing the exposure time that disinfecting concentrations of alcohol are present on skin. The improved alcohol-based antiseptics thus obtained are also claimed.

Abstract: The cosmetic composition of this is an ultraviolet ray-absorbing cosmetic composition containing particles of cyclic imino ester which is excellent in ultraviolet ray absorbability, stable against water, sparingly soluble in organic solvents, fats and oils, sebum, etc., and further has only a low skin-irritating property. When this cosmetic composition is applied onto the skin, erythema is not formed on/in the skin even if it is exposed to sunlight for a long period, and further aging of the skin can be prevented.

Abstract: Cell-stimulating composition having hair-growing effect and skin-vivifying effect. The composition comprising as an effective ingredient an aliphatic alcohol having odd number of carbon atoms or a derivative thereof in a cosmetically acceptable carrier.

Abstract: A cosmetic product is disclosed in the form of a gelatin walled capsule encompassing a cosmetic composition that includes a carrier which is a silicone polymer and an antioxidant. The antioxidant operates to inhibit degradation of the gelatin wall to prevent malodors from being generated. Retinoic acid derivatives such as retinyl palmitate are especially effective as antioxidants.

Abstract: A method for preventing frostbite of body portions is disclosed. The method includes applying an antiperspirant composition to the body portion and covering the body portion with a thermally insulating material.

Abstract: Feet and pedal portions of the human body are efficaciously conditioned against, and to circumvent and at least substantially preclude or alleviate, the discomfort and distress of offensive and frequently intolerable or at least disagreeable (including, without limitation thereto, the odiferous aspects thereof) sweating and perspiration by a particularized and carefully confined treatment with critically-concentrated aqueous solution(s) of formaldehyde (which, chemically, is CH.sub.2 O); consequentially followed by a uniquely-sensitive drying procedure to attain satisfactory, longeval cure or remedy of and relief and respite from possible sweaty conditions and circumstances and resultants thereof.

Abstract: A stable soothing hydroalcoholic skin preparation for shaving purposes employing alcohol as a carrier or solvent for the remainder of the composition comprising a combined allantoin-boric acid hydrolyzed solution in combination with glycerine, menthol, ethyl alchohol and fragrance.

Abstract: Skin care cosmetic formulations which include a cellulosic polymer/solvent system capable of dispersing thin, substantive films on the skin are disclosed.

Abstract: A cosmetic composition for the treatment of the hair and skin comprises at least 5 weight percent of pulverized particles of at least one plant. The particles have a granulometry lower than 125 microns. The compositions also includes a cohesion agent in an amount to maintain the homogeneity of the composition.

Abstract: Disclosed are antiperspirant gel stick compositions substantially free of unbound water comprising from about 5 to about 50% of a solubilized antiperspirant active, from about 7% to about 35% of intermediate polarity emollients, from about 1% to about 5% of a benzylidene sorbitol, from about 15% to about 75% of a polar solvent, from about 1% to about 20% of a coupling agent and from about 0.5% to about 10% of a bufferieng agent. These antiperspirant gel sticks provide very stable antiperspirant compositions with good efficacy as well as excellent cosmetic anesthetics which are further characterized by their ease of manufacture. Also disclosed is a method for the manufacture of these gel sticks as well as a method for treating or preventing perspiraton and malodor associated with human underarm perspiration.

Abstract: A topical antiperspirant composition containing an antihistamine selected from the group consisting of antazoline, pyrilamine, tripelennamine, diphenhydramine, phenindamine and their corresponding pharmaceutically acceptable salts and an enhancer for said antihistamine selected from the group consisting of sodium sulfate, glutamic acid; octyl palmitate and propylene glycol methyl ether.