Eczema Patents (Class 514/861)
  • Patent number: 8906375
    Abstract: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-22 (IL-22) and methods of using those antibodies, for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, septic shock, infectious disorders, transplant rejection, cancer, and other immune system disorders.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: December 9, 2014
    Assignee: Wyeth LLC
    Inventors: Lynette A. Fouser, Martin Hegen, Deborah P. Luxenberg, Margot O'Toole
  • Patent number: 8784780
    Abstract: Described herein are high oil-content emulsions and compositions for the treatment of inflammatory skin disorders. The emulsions may be formulated as aerosol compositions. The aerosol propellant may be a hydrofluoroalkane propellant. The emulsions or compositions may comprise active agents, such as corticosteroids. Also described are methods of treating inflammatory skin disorders, comprising the step of applying to an affected area of a subject in need thereof a therapeutically-effective amount of an inventive emulsion or aerosol composition.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: July 22, 2014
    Assignee: Precision Dermatology, Inc.
    Inventors: Ronald M. Gurge, Mark W. Trumbore, Lisa Chin, Poonam S. Hirani
  • Patent number: 8709385
    Abstract: Pharmaceutical or cosmetic compositions and methods for their use are provided comprising water and a surfactant polymer system comprising a Poloxamer at a concentration of about 0.1% to about 15% by weight; wherein when the Poloxamer is between about 0.1% to about 5% Poloxamer. The composition can further comprise a supporting agent comprising a non-ionic surface active agent or a supporting agent comprising a non surfactant polymer or polysaccharide and an active agent, where the Poloxamer is capable of fixing the composition on delivery to a body surface. There are further provided therapeutic cell compositions and their uses.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: April 29, 2014
    Assignee: Foamix Ltd.
    Inventors: Dov Tamarkin, Alex Besonov, Tal Berman, David Schuz, Elana Gazal
  • Patent number: 8679512
    Abstract: Topically administering a propellant-free formulation as a spray in the form of aqueous suspension of drug particles, wherein said formulation consists essentially of: micronized particles of beclometasone dipropionate (BDP) suspended in an aqueous phase, said aqueous phase comprising: an emulsifying agent selected from the class of polysorbates in an amount of 0.1 to 0.2% w/v, based on the total volume of the formulation; a sugar or a sugar alcohol in an amount of 5.0 to 5.2% w/v, based on the total volume of the formulation; a mixture of microcrystalline cellulose and carboxymethylcellulose sodium in an amount of 0.5 to 1.0% w/v, based on the total volume of the formulation; one or more preservatives; and water up to 100%, is effective for the prophylaxis and/or treatment of a dermatological disease such as atopic dermatitis, acne and psoriasis.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: March 25, 2014
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventor: Salvatore Criscione
  • Patent number: 8609718
    Abstract: Disclosed is a novel use of phytosphingosine. More particularly, disclosed are a composition for preventing or treating hyper-proliferative skin diseases comprising pachastrissamine as an active ingredient, a use of pachastrissamine or a pharmaceutically acceptable salt thereof for preparing a preventing/therapeutic agent of hyper-proliferative skin diseases, and a method for treating hyper-proliferative skin diseases administering an effective amount of pachastrissamine or a pharmaceutically acceptable salt thereof to a subject in need thereof. The pachastrissamine inhibits the degradation of FoxO3a protein and increases the expression of FoxO3a protein. Thus, the inventive pharmaceutical composition has a preventing of treating effect on hyper-proliferative diseases by inducing apoptosis of hyper-proliferative cells and inhibiting the cell cycle.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: December 17, 2013
    Assignee: Catholic University Industry Academy Cooperation Foundation
    Inventors: Dong Heon Shin, Tae Yoon Kim
  • Patent number: 8529970
    Abstract: Materials with high levels of unsaponifiable matter, such as extracts from plants, produce hydrolysates with unique properties. Properties that are sought in traditional saponification of natural oils are a result of low levels of unsaponifiables. These properties include high levels of aqueous surfactant activity, water-solubility or ready water-dispersability, activity as foaming agents, and the like. An objective of traditional saponification processes is to increase the water-solubility and surfactant activity of naturally occurring materials. It has been found that the application of a hydrolysis process to materials, particularly materials with a high level of unsaponifiables (e.g., at least 6 weight percent of the material), produces a product with properties significantly different from those products resulting from the conventional saponification of materials with less than 6 weight percent of unsaponifiables.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: September 10, 2013
    Assignee: International Flora Technologies, Ltd.
    Inventors: James H. Brown, Lee Roy Copeland, Robert Kleiman, Melanie K. Cummings, Sambasivarao Koritala
  • Patent number: 8513249
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.4% to about 0.6% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: August 20, 2013
    Assignee: Galderma Laboratories, L.P.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-Sang Liu, Matthew J. Leoni
  • Patent number: 8513247
    Abstract: Improved methods and compositions for safe and effective treatment of erythema or a symptom associated with erythema in a subject are described. The methods involve topically applying to an affected skin area a topical composition comprising about 0.4% to about 0.6% by weight of brimonidine and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: August 20, 2013
    Assignee: Galderma Laboratories, L.P.
    Inventors: Michael Graeber, Christian Loesche, Philip Freidenreich, Yin-Sang Liu, Matthew J. Leoni
  • Patent number: 8512718
    Abstract: A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepared by mixing 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, by weight, wherein at least one of them has therapeutic or cosmetic benefits, in the presence or absence of a biologically active substance.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: August 20, 2013
    Assignee: Foamix Ltd.
    Inventors: Meir Eini, Dov Tamarkin
  • Patent number: 8501202
    Abstract: A topical composition for the treatment of mammalian skin dermatoses comprising a sulfacetamide or a derivative thereof and at least 1 sunscreen wherein the sunscreen is present in a sufficient amount to produce a sun protection factor of about 1.6 to about 20.6. Also provided is a method of treating mammalian dermatoses by administering a topical composition comprising a sulfacetamide or a derivative thereof and at least 1 sunscreen wherein the sunscreen is present in a sufficient amount to produce a sun protection factor of about 1.6 to about 20.6.
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: August 6, 2013
    Assignee: Aqua Pharmaceuticals, LLC
    Inventor: Charles W. Stiefel
  • Patent number: 8470887
    Abstract: Provided, among other things, is a delivery module for a non-greasy, water-based urea composition comprising: an aerosol delivery device; within the aerosol delivery device, the urea composition comprising 20% or more urea by weight, non-greasy lipophilic component(s), and a frothing agent, the urea composition having a viscosity low enough to support aerosol delivery, and the urea composition effective to form a foam upon propellant-driven aerosol delivery; and within the aerosol delivery device, a propellant.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: June 25, 2013
    Assignee: Quinnova Pharamaceuticals, Inc.
    Inventor: Mats Silvander
  • Patent number: 8466128
    Abstract: The present invention provides compositions suitable for topical administration to a mammalian subject including sodium hyaluronate and a pharmaceutically acceptable excipient. The present invention also provides methods for malting and using the same.
    Type: Grant
    Filed: January 29, 2008
    Date of Patent: June 18, 2013
    Assignee: Cypress Pharmaceuticals, Inc.
    Inventor: Robert Lewis
  • Patent number: 8440704
    Abstract: This invention relates to a composition containing quercetin, vitamin B3, and vitamin C. Also disclosed is a method of using the composition for enhancing physical or mental performance or treating various diseases or disorders.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: May 14, 2013
    Assignee: Quercegen Pharmaceuticals LLC
    Inventor: Thomas Christian Lines
  • Patent number: 8399694
    Abstract: An object of the present invention is to provide a more simplified and more efficient process for producing a highly purified orange roughy oil having high storage stability. The present invention provides a process for producing a highly purified orange roughy oil substantially free of a polyunsaturated fatty acid ester having 4 to 6 double bonds, and having a saponification value of 98 to 113 and an iodine value of 73 to 89, comprising washing with an alkaline aqueous solution to remove a free fatty acid; hydrogenating with a catalyst to reduce a polyunsaturated fatty acid ester; and purifying by treatment with an adsorbent.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: March 19, 2013
    Assignee: Nippon Suisan Kaisha, Ltd.
    Inventors: Kazuhiko Hata, Akito Yamabe, Tsuyoshi Koriyama
  • Patent number: 8338484
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: December 25, 2012
    Assignee: Panmira Pharmaceuticals, LLC
    Inventors: John Howard Hutchinson, Brian Andrew Stearns, Yen Pham Truong
  • Patent number: 8309074
    Abstract: The present invention relates to the field of probiotics. More particularly, the invention pertains to the use of a particular strain, Lactobacillus casei CNCM I-1518, which is present in Actimel®, for alleviating the symptoms of a delayed-type hypersensitivity reaction.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: November 13, 2012
    Assignee: Compagnie Gervais Danone
    Inventors: Jean François Nicolas, Catherine Goujon, Raphaëlle Bourdet-Sicard, Nathalie Rolf-Pedersen
  • Patent number: 8287846
    Abstract: The present invention relates to odour improved dermatological or cosmetic preparations comprising N-acetylcysteine and a polyol system containing one or more polyols as masking odour agents. The emulsions of the present invention are useful in the treatment of dermatological disorders or cosmetic skin conditions.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: October 16, 2012
    Assignee: ZAMBON S.p.A.
    Inventors: Luca Rampoldi, Alberto Moretto, Alessandro Grassano
  • Patent number: 8236836
    Abstract: The invention concerns a composition containing at least an oxazolin, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an alkanolamide, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such composition on the skin and/or mucosa.
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: August 7, 2012
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Nathalie Piccardi, Antoine Piccirilli
  • Patent number: 8227490
    Abstract: Compounds of the formula (I) are disclosed and are suitable for the treatment of seborrheic dermatitis.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: July 24, 2012
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Manfred Bohn, Karl Theodor Kraemer, Astrid Markus
  • Patent number: 8147883
    Abstract: The invention concerns the use of at least a vegetable oil product selected among the group consisting of vegetable oil oleic distillates, vegetable oil unsaponifiable matters, vegetable oil furan lipids and mixtures thereof, as agents for increasing skin lipid synthesis, in particular lipids of the epidermal skin barrier, in or for preparing a composition containing a pharmaceutically or dermatologically acceptable medium. The use enables to prevent and/or treat deterioration of the skin barrier (dry skin, skin subjected to actinic radiation, ichthyosis, acne, xerosis, atopic dermatitis, sensitive skin, chafing and reactive skin, itching and the like).
    Type: Grant
    Filed: September 20, 2000
    Date of Patent: April 3, 2012
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Antoine Piccirilli
  • Patent number: 8101664
    Abstract: Provided, among other things, is a delivery module for a non-greasy, water-based urea composition comprising: an aerosol delivery device; within the aerosol delivery device, the urea composition comprising 20% or more urea by weight, non-greasy lipophilic component(s), and a frothing agent, the urea composition having a viscosity low enough to support aerosol delivery, and the urea composition effective to form a foam upon propellant-driven aerosol delivery; and within the aerosol delivery device, a propellant.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: January 24, 2012
    Assignee: Quinnova Pharmaceuticals, Inc.
    Inventor: Mats Silvander
  • Patent number: 8053003
    Abstract: The present invention relates to the use of a plant oil product as an agent for increasing the synthesis of skin lipids, especially the lipids of the epidermal skin barrier, in or for the preparation of a cosmetic, pharmaceutical or dermatological composition. The invention also relates to a method for cosmetic treatment with a cosmetic, pharmaceutical or dermatological composition for increasing the synthesis of skin lipids, especially the lipids of the epidermal skin barrier, and to the use of the plant product as a food additive.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: November 8, 2011
    Assignee: Laboratoires Expanscience
    Inventors: Philippe Msika, Antoine Piccirilli
  • Patent number: 7981909
    Abstract: Compounds of the formula (I) are disclosed and are suitable for the treatment of seborrheic dermatitis.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: July 19, 2011
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Manfred Bohn, Karl Theodor Kraemer, Astrid Markus
  • Patent number: 7960430
    Abstract: The invention relates to complexes of certain flavonoid derivatives, of the formula I compositions which comprise such derivatives, corresponding processes for the preparation of the flavonoid derivatives or of compositions comprising same, and the use thereof, in particular for the care, preservation or improvement of the general state of the skin or hair. Formula (1), in which Z1 to Z4 and Z6 to Z10 each, independently of one another, denote H, OH, CH3COO, alkoxy, hydroxyalkoxy, mono- or oligoglycoside radicals and where the alkoxy and hydroxyalkoxy groups may be branched and unbranched and can have 1 to 18 C atoms. Formula (II) denotes, Z5 is a mono- or the oligoglycoside radical, where bonded to this glycoside radical, in each case via an —O— group, is at least one radical selected from certain benzo molecule.
    Type: Grant
    Filed: December 27, 2004
    Date of Patent: June 14, 2011
    Assignee: Merck Patent GmbH
    Inventors: Corinna Wirth, Ralf Rosskopf, Herwig Buchholz
  • Patent number: 7902173
    Abstract: The present invention provides a compound selected from sulfated cellulose and salts thereof which can be used as an active ingredient for a cutaneous external preparation produced intending to prevent, soften, improve or cure atopic cutaneous symptoms and the like and which are excellent in a hydrolytic resistance, and dermatitis therapeutic agents and cosmetics using the same.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: March 8, 2011
    Assignees: Chisso Corporation, Chisso Petrochemical Corporation
    Inventors: Naoyuki Yoshida, Kazushi Ishida, Shuji Sasaki, Takuo Ikeda, Jun Hiraki, Shigeyuki Aoyama
  • Patent number: 7829107
    Abstract: Novel compositions of matter comprising a foamable delivery system are provided. Novel methods for treating a disease, disorder, or condition using the novel compositions are further provided. Novel methods for making and delivering a foamable pharmaceutical composition are also provided. While the novel compositions and foamable drug delivery system may be utilized for administration of a wide variety of drugs to epithelial tissues, to treat a wide variety of diseases, disorders, or conditions, the inventive compositions and foamable drug delivery systems are particularly useful for the dermatological administration of corticosteroids and antifungal agents.
    Type: Grant
    Filed: November 13, 2006
    Date of Patent: November 9, 2010
    Assignee: Stiefel Laboratories, Inc.
    Inventors: Karl F. Popp, Edward R. Yuhas
  • Patent number: 7737182
    Abstract: A method for or treating xerosis by applying a prostaglandin D receptor selective agonist to a mammal.
    Type: Grant
    Filed: February 4, 2005
    Date of Patent: June 15, 2010
    Assignees: Taisho Pharmaceutical Co., Ltd., Fumie Sato
    Inventors: Iwao Arai, Nobuko Futaki, Yuki Hashimoto, Masanori Sugimoto
  • Patent number: 7718701
    Abstract: A method of treating atopy-evoked pruritic symptoms by administering a prostaglandin derivative.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: May 18, 2010
    Assignees: Taisho Pharmaceutical Co., Ltd., Fumi Sato
    Inventors: Fumie Sato, Iwao Arai, Norikazu Takano, Tohru Tanami, Makoto Yagi
  • Patent number: 7670620
    Abstract: Compositions and methods of use thereof for the treatment of psoriasis and related skin ailments are disclosed. The compositions include topical skin formulations of glucosamine in an emollient base such as moisturizing cream. In addition to glucosamine, the formulations may include keratolytic substances such as coal tar extract or salicylic acid. The formulations may also include glucosamine and antioxidant anti-inflammatory herbal extracts such as oleuropein and berberine in an emollient base.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: March 2, 2010
    Assignee: Bioderm, Inc.
    Inventor: Lorraine Faxon Meisner
  • Patent number: 7666451
    Abstract: A method of use for a topical herbal formulation alone or in combination with oral administration of niacin (preferably a flush preparation) to prevent and/or treat dyshidrosis (pompholyx) and related skin diseases. The formulation may also be used to treat contact dermatitis, eczema, palmoplantar pustulosis and skin infections incurred by invasive pathogens such as mold, fungus and bacteria. The formulation is comprised of plant extracts and niacin, that when combined yield an effective multi-faceted pharmaceutical approach to treating dry skin disorders.
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: February 23, 2010
    Inventors: Elizabeth Anne Mazzio, Karam F Soliman
  • Patent number: 7468361
    Abstract: Biologically active 19-nor vitamin D analogs substituted at C-2 in the A-ring with an ethylidene or an ethyl group. These compounds have preferential activity on mobilizing calcium from bone and either high or normal intestinal calcium transport activity which allows their in vivo administration for the treatment of metabolic bone diseases where bone loss is a major concern. These compounds are also characterized by high cell differentiation activity.
    Type: Grant
    Filed: August 16, 2007
    Date of Patent: December 23, 2008
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Hector F. DeLuca, Rafal R. Sicinski
  • Patent number: 7357938
    Abstract: A method for treating rosacea in a patient comprising administering to a patient suffering from rosacea a first topical composition comprising at least one sulfacetamide or a derivative thereof and at least one sunscreen, wherein the administration of said first composition provides a more effective treatment of said rosacea in comparison to treatment of rosacea achieved by administration of a second topical composition comprising metronidazole.
    Type: Grant
    Filed: September 10, 2004
    Date of Patent: April 15, 2008
    Assignee: Stiefel Laboratories, Inc.
    Inventor: Charles W. Stiefel
  • Patent number: 7341746
    Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: March 11, 2008
    Assignee: Phytotech Limited
    Inventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
  • Patent number: 7238676
    Abstract: The present invention relates to compounds of the formula and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as adenosine A2a receptor agonists.
    Type: Grant
    Filed: June 15, 2004
    Date of Patent: July 3, 2007
    Assignee: Pfizer Inc.
    Inventors: Simon John Mantell, Sandra Marina Monaghan, Peter Thomas Stephenson
  • Patent number: 7201925
    Abstract: The treatment of ungual and subungual diseases is disclosed.
    Type: Grant
    Filed: February 2, 2004
    Date of Patent: April 10, 2007
    Assignee: Nueryst Pharmaceuticals Corp.
    Inventor: Scott H. Gillis
  • Patent number: 7195781
    Abstract: This invention relates to a method for the natural topical treatment of portions of skin of a person afflicted with a skin disorder such as dry skin, eczema, itchy skin, red skin, itchy eczema, inflamed skin, and/or cracked skin for the removal of itch and the restoration of the affected areas of skin to a normal condition. The natural treatment of a skin disorder initially involves formation of a natural ointment from the ingredients identified as lard; Marigold flowers; and pure beeswax. The natural ointment is formed by combination of the ingredients which includes heating. The ointment is then applied twice daily to affected areas of skin until a natural cure of the skin disorder is obtained. In addition, a therapeutic compress is applied to the affected skin. The compress may include Colts Foot Leaf, White Oak Bark, Burdock Root, Horsetail Herb, and water.
    Type: Grant
    Filed: July 13, 2004
    Date of Patent: March 27, 2007
    Inventor: Bronhilda Miketin
  • Patent number: 7186754
    Abstract: The present invention relates to the use of creatine compounds such as, for example, creatine, creatine phosphate or analogs of creatine, such as creatine-pyruvate, creatine-ascorbate, cyclocreatine, 3 guanidinopropionic acid, guanidinoacetate, homocyclocreatine, guanidino benzoates as energy generating systems and antioxidants for preservation of skin against adverse aging effects and damage secondary to insults such as harmful sun radiations, stress and fatigue. The creatine compounds which can be used in the present method include (1) creatine, creatine phosphate and analogs of these compounds which can act as substrates or substrate analogs for creatine kinase; (2) molecules that mimic the biological activity of creatine (3) molecules that modulate the creatine kinase system.
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: March 6, 2007
    Assignee: Avicena Group, Inc.
    Inventor: Rima Kaddurah-Daouk
  • Patent number: 7166582
    Abstract: The present invention provides a sate and excellent antiallergic composition, and more particularly a preventive and therapeutic composition for atopic dermatitis, including an antiallergic composition blended with stachyose as an effective ingredient, and a medicine, food and beverage containing the composition.
    Type: Grant
    Filed: July 25, 2005
    Date of Patent: January 23, 2007
    Assignee: J-Oil Mills, Inc.
    Inventors: Toshiro Sato, Shuichi Kamo, Yutaka Ohtani, Yasushi Ueno
  • Patent number: 7132412
    Abstract: A new use of a suitable colloidal mixture of hyaluronic acids, of different molecular weights mixed together in a proper ratio in the treatment of the cutaneous diseases is described.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: November 7, 2006
    Inventors: Giuseppe Petrigni, Luigi Allegra
  • Patent number: 7109246
    Abstract: A formulation, for example an oil-in-water emulsion, comprising an amphoteric surfactant, alkoxylated cetyl alcohol and a polar drug. The drug may be sodium cromoglycate or nedocromil sodium. The formulation may be useful in the treatment of skin disease such as atopic dermatitis.
    Type: Grant
    Filed: May 20, 1999
    Date of Patent: September 19, 2006
    Assignee: Hewlett Healthcare Ltd
    Inventor: Brian Hawtin
  • Patent number: 7090871
    Abstract: Petasite preparations without hepatotoxic, carcinogenic, cytostatic and/or mutagenic effect with a rapid and/or improved action are provided. The petasite extract is recovered from a plant and/or plant parts of the genus Petasites, the petasite extract being free of pyrrolizidine alkaloids, and in which magnesium and/or other pharmacologically and/or physiologically active substances are optionally added. The extract is effective in treating a wide variety of indications, such as gastrointestinal diseases, asthmas, pollinosis, dysmenorrhea, eczemas, migraines, psoriasis and high blood pressure.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: August 15, 2006
    Assignee: Weber & Weber GmbH & Co. KG
    Inventors: Volkmar Koch, Reiner Rittinghausen
  • Patent number: 7029659
    Abstract: A topical mousse composition including an occlusive agent; an aqueous solvent; and an organic cosolvent, wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin.
    Type: Grant
    Filed: January 27, 2004
    Date of Patent: April 18, 2006
    Assignee: Connetics Australia Pty Ltd.
    Inventor: Albert Zorko Abram
  • Patent number: 7022332
    Abstract: The present invention provides improved sulfacetamide and sulfur formulations including sunscreens for the treatment of rosacea.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: April 4, 2006
    Assignee: Stiefel Laboratories, Inc.
    Inventor: Charles W. Stiefel
  • Patent number: 6979468
    Abstract: A method and composition for the treatment of acne vulgaris, acne rosacea, and other inflammatory skin conditions comprises the oral administration of a composition comprising a dose of nicotinamide delivered at levels substantially in excess of normal dietary levels, the nicotinamide being delivered in combination with zinc. The composition may also include quantities of copper and folic acid. In a most preferred embodiment, the nicotinamide and copper each are present in immediate release formats, while the zinc is present in a sustained release format.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: December 27, 2005
    Assignee: Sirius Laboratories
    Inventor: Frank Pollard
  • Patent number: 6958153
    Abstract: The present invention relates to a topical formulation for the treatment of a dermatological condition which comprises a macrocyclic lactone antibiotic, immunosuppresive macrolide or a biologically active analogue, derivative or pro-drug thereof; characterized in that it further comprises a permeation modulator and the permeation modulator and the macrocyclic lactone or macrolide or the biologically active analogue, derivative or pro-drug thereof are present in relative amounts such that when a therapeutic amount is applied to the skin a minimal systemic effect is produced. The immunosuppressive macrolide may be sirolimus.
    Type: Grant
    Filed: November 5, 1998
    Date of Patent: October 25, 2005
    Assignee: Wyeth
    Inventors: Anthony David Ormerod, Arthur Winfield
  • Patent number: 6939568
    Abstract: The invention relates to the use of one or more antimicrobial metals, most preferably silver, preferably formed with atomic disorder, and preferably in a nanocrystalline form, for the treatment of inflammatory skin conditions. The nanocrystalline antimicrobial metal of choice may be used in the form of a nanocrystalline coating of one or more antimicrobial metals, a nanocrystalline powder of one or more antimicrobial metals, or a solution containing dissolved species from a nanocrystalline powder or coating of one or more antimicrobial metals.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: September 6, 2005
    Assignee: Nucryst Pharmaceuticals Corp.
    Inventors: Robert Edward Burrell, Hua Qing Yin
  • Patent number: 6867238
    Abstract: Compositions are provided for the topical treatment of cancer consisting of lotions, creams, sprays, suppositories or slow-release transdermal patches containing lipid-soluble, skin-penetrating organic selenium compounds in combination with inert carriers in therapeutically effective amounts of selenium compound. The selenium compounds are medium linear chain dialkyl diselenides and precursors such as alkyl selenols. Preferred compositions employ R—Se—Se—R compounds where R is from 6 to 8 carbon atoms, and most specifically di-n-hexyl diselenide. Commonly used carriers may be purified hydrocarbon fractions, oils, with or without added fat-soluble vitamins, water and emulsifying agents.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: March 15, 2005
    Inventor: Gerhard N. Schrauzer
  • Patent number: 6863907
    Abstract: An allergy preventive or itching preventive food containing persimmon leaves or a persimmon leaf extract, a persimmon leaf extract-containing cosmetic composition having the action of improving allergic rough skin conditions or alleviating itching, an allergy or itching preventive or therapeutic composition.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: March 8, 2005
    Assignees: Sunstar, Inc., Uni-Sunstar B.V.
    Inventors: Mayumi Kotani, Akihito Fujita, Motonobu Matsumoto
  • Patent number: 6770635
    Abstract: Adverse inflammatory reactions can be treated by administrating to an organism a composition having diglucosylamine as the active ingredient. The preferred compound is di-Beta-D-glucopyranosylamine. A simple method for making diglucosylamine in high purity is obtained by reacting glucose, a nitrogen containing base, and either methanol or ethanol to form the diglucosylamine and then recovering the diglucosylamine preferably with the use of charcoal. The preferred diglucosylamine, di-Beta-D-glucopyranosylamine, has extraordinary anti-inflammatory activity. It can be formulated with a pharmaceutically acceptable carrier to make pharmaceutical compositions which are effective in treating inflammations. This pharmaceutical composition can also be used to treat adverse inflammatory reactions that are the result of the disruptions of a dynamic network of cellular mechanisms in organisms.
    Type: Grant
    Filed: December 4, 1997
    Date of Patent: August 3, 2004
    Assignee: Pharos Pharmaceuticals
    Inventor: Clairmont G. Drube
  • Patent number: 6756060
    Abstract: Compositions and methods for treating wounds to significantly reduce the healing time, reduce the incidence of scar formation, improve the success of skin grafts, reduce the inflammatory response and providing anti-bacterial treatments to a patient in need thereof, that include small non-interlinked particles of bioactive glass or highly porous bioactive glass, are disclosed. Anti-bacterial solutions derived from bioactive glass, and methods of preparation and use thereof, are also disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with anti-bacterial agents and/or anti-inflammatory agents. The compositions can include an appropriate carrier for topical administration. Anti-bacterial properties can be imparted to implanted materials, such as prosthetic implants, sutures, stents, screws, plates, tubes, and the like, by incorporating small bioactive glass particles or porous bioactive glass into or onto the implanted materials.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: June 29, 2004
    Assignee: USBiomaterials Corp.
    Inventors: David C. Greenspan, Jon K. West, Sean Lee, James L. Meyers, Mason Diamond