Diaper Rash Patents (Class 514/865)
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Patent number: 5762945Abstract: A topical composition for the treatment of the symptoms of diaper rash is disclosed comprising the combination of equal rations of nystatin powder, zinc oxide, and AQUAPHOR (.TM.), and mixed with a larger volume of U.S.P. cold cream.Type: GrantFiled: April 5, 1996Date of Patent: June 9, 1998Inventor: Eline Ashley
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Patent number: 5744469Abstract: The invention provides a method for treating fungal dermatitis comprising administering an effective amount of 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno?2,3-b!?1,5!benzodiazepine to a patient in need thereof.Type: GrantFiled: November 26, 1996Date of Patent: April 28, 1998Assignee: Eli Lilly and CompanyInventor: Pierre V. Tran
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Patent number: 5645826Abstract: A method of treating damaged tissue by applying a composition to the damaged tissue in an amount effective to treat the damaged tissue. The composition includes a semi-occlusive ointment base and salicylic acid in an amount effective to produce keratoplasticity.Type: GrantFiled: May 31, 1996Date of Patent: July 8, 1997Assignee: Abbe Cosmetic Group International, Inc.Inventor: Robert M. Posner
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Patent number: 5618850Abstract: A method for alleviating the symptoms of a cosmetic or dermatologic skin condition is described. An effective amount of a poly(hydroxy acid)/polymer conjugate in a pharmaceutically or cosmetically acceptable vehicle is provided. Topical compositions of the conjugates with another cosmetic or dermatological agent, and compounds of the conjugates having attached physiologically active functional groups, are also provided.Type: GrantFiled: March 9, 1995Date of Patent: April 8, 1997Assignee: Focal, Inc.Inventors: Arthur J. Coury, Luis Z. Avila, Chandrashekhar P. Pathak, Shikha P. Barman
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Patent number: 5618529Abstract: An improved method of treating diaper rash in both infants and adults is described. The method entails coating the affected area with a composition containing a copolymer of a lower alkyl vinyl ether and maleic acid, or a derivative of the copolymer.Type: GrantFiled: October 11, 1994Date of Patent: April 8, 1997Inventor: Virgil F. Pichierri
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Patent number: 5512200Abstract: Low pH acidic compositions for uses related generally to chemical, pharmaceutical and cosmetic agents and more particularly, but not limited to, used as bactericides, fungicides, germicides and virucides; all having pH values of less than about 2.0 in their final form. These low pH acidic compositions generally comprise two phases in solution. Phase I comprises from about 2 to about 98 weight percent of varying percentages of several chemical, pharmaceutical and cosmetic substances.Phase II comprises from about 2 to about 99 weight percent of an active aqueous acidic component having a pH value of less than about 1.Type: GrantFiled: April 18, 1994Date of Patent: April 30, 1996Assignee: Thomas G. BongardInventor: Silverio M. Garcia
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Patent number: 5466452Abstract: A process is provided which is suitable for the preparation of herbal compositions for the treatment of skin disorders such as eczema and psoriasis. The process comprises preparing an extract or extracts of herbs which provide an anti-inflammatory agent, an adrenocortical stimulant and a cortisol protecting agent by steam distillation and decoction and then treating the extracts to reduce the polysaccharide and/or sugar content. This is achieved by fermentation or enzymic action or by extraction with a solvent having a polarity in the range E.degree. 0.4 to 0.95 or by precipitation with an inorganic compound and/or colloid or by a combination of two or more of the above. As a final concentration step, the material is further purified by extraction with a solvent having a polarity in the range mentioned above. The reduction of the sugar/polysaccharide content greatly improves the handling characteristics of the extract which can be dried to a free flowing powder.Type: GrantFiled: August 26, 1993Date of Patent: November 14, 1995Assignee: Phytopharm Ltd.Inventor: Brian A. Whittle
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Patent number: 5455232Abstract: The invention relates to a pharmaceutical preparation comprising as an active ingredient at least one rhamnolipid or a pharmaceutically acceptable salt thereof, and a carrier and/or diluent, preferably comprising a rhamnolipid of the general formula: ##STR1## wherein R.sub.1 =H, alpha-L-rhamnopyranosyl; ##STR2## R.sub.3 =(C.sub.5 -C.sub.20)-saturated, -mono- of poly-unsaturated alkyl; R.sub.4 =(C.sub.5 -C.sub.Type: GrantFiled: April 7, 1994Date of Patent: October 3, 1995Inventors: Goran Piljac, Visnja Piljac
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Patent number: 5420114Abstract: A dermatological pharmaceutical composition for stimulating hair growth and for the treatment of conditions of the skin selected from the group consisting of(a) benign moles, papillomas and seborrheic keratoses;(b) unsightly freckles, pimples and blemishes;(c) stasis dermatitis;(d) dermal ulcers; and(e) fungal nail infections; and(f) gingival and mucous membrane inflammations;the composition comprising an effective amount of tannic acid, a debriding agent and a pharmaceutically acceptable carrier therefore.Type: GrantFiled: July 7, 1993Date of Patent: May 30, 1995Inventors: Percy B. Clodman, Ossie Clodman
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Patent number: 5409691Abstract: Solution comprising a mixture of aluminum acetate topical solution and glycerin useful as a skin moisturizer and/or a food particulate repellant for preventing chewed food particles from sticking to the teeth. When combined with a flavoring agent, the solution of aluminum acetate topical solution and glycerin is also effective as a saliva substitute for relieving the symptoms of xerostomia or "dry mouth syndrome.Type: GrantFiled: October 18, 1993Date of Patent: April 25, 1995Inventor: Dan E. Swain
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Patent number: 5409903Abstract: A method of treating a mammal for the presence or the activity of H. pylori in the gastrointestinal tract is disclosed. The method encompasses orally administering to said mammal a sufficient amount of a scavenging, reacting or inactivating compound to remove bicarbonate ions, ammonium ions or urea which are present in combination with the microorganisms which colonize and infect the gastric mucosa. Such microorganisms have been implicated in gastritis, gastric ulcer disease and as a risk factor in gastric carcinoma.Also, the invention encompasses a method, utilizing similar compounds, for the treatment or prevention of dermatitis such as diaper rash wherein these compounds are preapplied to the skin or used to treat the diaper prior to use.Also included are compositions which are used for the methods described above.Type: GrantFiled: February 18, 1992Date of Patent: April 25, 1995Assignee: Urecap CorporationInventors: Robert B. Polak, Attallah Kappas
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Patent number: 5362488Abstract: A buffered skin cream containing a linear polydimethylsiloxane polymer, a non-ionic emulsifier, aloe vera, mineral oil, sodium citrate, citric acid, a blend of propylene glycol, diazolidinyl urea, methyl paraben and propyl paraben, and water. The buffering capacity of the cream is provided through the incorporation of citric acid and sodium citrate in the composition. The buffering system results in the cream having a preferred pH in the range of about 4.5 to 6.0, and most preferably a pH of about 5.2 which neutralizes acidic and basic by-products of urine and fecal matter. The cream has a preferred viscosity in the range of 100,000-2,000,000 centipoise and a most preferred viscosity of about 250,000 to 1,000,000 centipoise. The cream is easily washed off with soap and water and is useful in the protection and treatment of diaper rash.Type: GrantFiled: October 6, 1993Date of Patent: November 8, 1994Assignee: Abbott LaboratoriesInventors: Murray J. Sibley, Donald E. Hartung, Rosalyn Ruland
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Patent number: 5340579Abstract: A method is provided for treating dermatological conditions by binding and blocking 5-a-dihydrotestosterone receptors comprising applying to the skin an effective amount of composition comprising:(a) from about 0.1% to about 2.0% by weight of mucopolysaccharides free of proteins and having a pH ranging from about 5 to 7.5 in aqueous solution, a rotary power between about to +15, and a sulfur content greater than 6%;(b) from about 1% to about 3% by weight of an aqueous extract of human umbilical cord free from sulfur and having a DH of from about 5 to about 7, a viscosity of 30.degree. C. of from 10 to 25 centistokes, a hyaluronic acid titre of from about 500 to about 700 mg/dl, and an ash content of less than about 0.5%;(c) from about 0.05 to about 0.08% by weight of tetrahydrofurfuryl nicotinate; and(d) pharmaceutically and cosmetically acceptable vehicles and excipients.Type: GrantFiled: June 20, 1990Date of Patent: August 23, 1994Assignee: Farmaka S.r.l.Inventor: Riccardo Casero, deceased
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Patent number: 5338535Abstract: This invention discloses a liquid body powder which is applied as a lotion or a cream and which then evaporates to a powder. By applying it as a lotion or cream, the cracks and pores of the skin are filled. By virtue of the volatility of the cyclic silicone fluid containing delivery vehicle and its evaporation, a powder results which leaves no greasy residue on the skin. The liquid powder according to the present invention comprises a purified starch powder mixed with a volatile cyclomethicone silicone fluid, preferably in equal amounts by weight.Type: GrantFiled: December 23, 1992Date of Patent: August 16, 1994Assignee: The Safe & Dry Company, Inc.Inventor: Dieter R. Berndt
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Patent number: 5300286Abstract: A silicone oil-in-water emulsion composition and a method of topically treating human skin with the composition. The emulsion constitutes water, a silicone oil, and at least two nonionic emulsifiers. Each nonionic emulsifier is a solid at room temperature. One nonionic emulsifier has an HLB value less than 8.0, while the other nonionic emulsifiers has an HLB value greater than 15.0.Type: GrantFiled: July 14, 1992Date of Patent: April 5, 1994Assignee: Dow Corning CorporationInventor: Ronald P. Gee
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Patent number: 5262161Abstract: A medicine for skin diseases contains a fermented and condensed extract from the stems of Stevia Rebaudiana Bertoni as an active ingredient. The medicine is prepared by condensing and fermenting an extract from the ripened stems of Stevia Rebaudiana Bertoni by multi-stage condensation followed by fermentation and ripening of the condensed extract. It is effective for various skin diseases and other diseases caused by blood circulation insufficiency.Type: GrantFiled: September 30, 1991Date of Patent: November 16, 1993Assignees: Fumio Dozono, Naohiko SatoInventor: Fumio Dozono
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Patent number: 5256403Abstract: Solubilized melanin based compositions supply melanin to skin, scalp and/or hair. The compositions consist of melanin, as an active ingredient, and a substance to solubilize the melanin blended together in a vehicle suitable for topical application. A melanin-based composition applied to the skin provides photoprotection of the human epidermis from exposure to ultraviolet rays. A melanin-based composition applied to wounds in the skin accelerates healing of the wounds. A melanin-based composition applied to the hair and scalp strengthens the hair.Type: GrantFiled: January 8, 1991Date of Patent: October 26, 1993Inventor: Frances C. Gaskin
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Patent number: 5229105Abstract: A skin preparation offering protection against a variety of irritants (including allergens) is prepared from an oil-in-water emulsion of the cationic type, with a fatty acid mono-ester or di-ester of triethanolamine, or a fatty acid amide of hydroxyethyl-ethylenediamine, as the cation and active barrier ingredient. The resulting emulsion binds strongly to the skin through electrostatic bonding and forms an invisible yet effective barrier that isolates the skin from adversely charged irritants, small organic compounds, irritants of high molecular weight, and irritants of alkaline pH. The skin preparation may incorporate additional active agents, such as sunscreens, antibiotics and other therapeutics, for application of these agents to the skin.Type: GrantFiled: April 6, 1992Date of Patent: July 20, 1993Assignee: Donald BasiliereInventor: Hermann Wilmsmann
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Patent number: 5194261Abstract: An improved method of treating diaper rash in both infants and adults is described. The method entails coating the affected area with a composition containing a copolymer of a lower alkyl vinyl ether and maleic acid, or a derivative of the copolymer.Type: GrantFiled: May 4, 1992Date of Patent: March 16, 1993Inventor: Virgil Pichierri
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Patent number: 5110593Abstract: A method and compositions for the irradication and treatment of diaper dermatitis and related skin disorders whereby the skin is first cleansed with a non-irritating agent. The cleansed area is then treated with a specially formulated topical ointment which contains at a minimum, but is not limited to, a skin conditioning agent, a barrier agent, and an antimicrobial agent combined with other vehicles which are chemically capable of ensuring delivery of the above agents in, at least minimum inhibitory concentration.Type: GrantFiled: November 13, 1990Date of Patent: May 5, 1992Inventor: M. Sue Benford
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Patent number: 5091379Abstract: Topical polyethylene glycol based formulations for the delivery of 2-substituted-1-naphthols and indoles and particularly, 2-phenylmethyl-1-naphthol are provided. Said topical formulations exert excellent localized antiinflammatory activity while demonstrating low levels of skin penetration in vitro and in vivo thereby reducing unwanted side effects and reducing systemic toxicity associated with the active drug compounds.Type: GrantFiled: August 31, 1989Date of Patent: February 25, 1992Assignee: Du Pont Merck Pharmaceutical CompanyInventor: Bruce J. Aungst
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Patent number: 5091193Abstract: A composition for preventing or treating diaper rash comprising an effective amount of zinc oxide and at least one antienzyme sufficient to treat or prevent diaper rash and an inert pharmaceutical carrier and a method of treating or preventing diaper rash on new-born babies.Type: GrantFiled: August 21, 1990Date of Patent: February 25, 1992Assignee: Roussel UclafInventors: Odile Enjolras, Hugues Noel
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Patent number: 5011689Abstract: The invention comprises a method of reducing rash formation and itching of skin caused by poison ivy. The method comprises breaking up a plant of the genus Plantago, preferably broadleaf Plantain, to release the sap therein and to form a fibrous pulp containing sap and applying an effective amount of the sap-containing pulp to the affected area of the skin.Type: GrantFiled: December 11, 1989Date of Patent: April 30, 1991Assignee: T. Paul MisenkoInventor: T. Paul Misenko
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Patent number: 5006337Abstract: Medicinal and cosmetic compositions for the treatment of skin disorders and for care of dry and/or irritated skin and of dry scalp with dandruff are prepared using brewers' grains extract(s)--especially a brewers' grains extract obtained using liquid or above-critical CO.sub.2 or N.sub.2 O.Type: GrantFiled: April 14, 1988Date of Patent: April 9, 1991Assignee: Marbert GmbHInventors: Lothar Motitschke, Hagen Tronnier
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Patent number: 4996238Abstract: A skin protective composition for exhibiting enhanced water repellency and conditioning effects containing aliphatic waxes and hydrophobic silicones in a nonallergenic, non-toxic, cosmetically acceptable carrier. The composition is useful to protect mammals from solar radiation and in the treatment of diaper rash.Type: GrantFiled: June 25, 1990Date of Patent: February 26, 1991Assignee: Neutrogena CorporationInventor: Peter Matravers
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Patent number: 4963591Abstract: Skin care cosmetic formulations which include a cellulosic polymer/solvent system capable of dispersing thin, substantive films on the skin are disclosed.Type: GrantFiled: December 16, 1985Date of Patent: October 16, 1990Assignee: Carter-Wallace Inc.Inventors: Robert G. Fourman, Richard P. Dixon, Hans Breuer
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Patent number: 4937234Abstract: A soluble mineral in bioavailable form is formed from a mineral salt of a carboxylic acid derivative of a pentose or hexose such as zinc gluconate and an amino acid having the ability of stabilize the mineral salt when the mixture id neutralized in the zone of intracellular pH. Methods of treating an organism with the above-mentioned minerals are disclosed.Type: GrantFiled: August 10, 1988Date of Patent: June 26, 1990Inventor: Mostafa S. Fahim
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Patent number: 4933177Abstract: A cosmetic composition for the treatment of the hair and skin comprises at least 5 weight percent of pulverized particles of at least one plant. The particles have a granulometry lower than 125 microns. The compositions also includes a cohesion agent in an amount to maintain the homogeneity of the composition.Type: GrantFiled: June 15, 1988Date of Patent: June 12, 1990Assignee: Societe Anonyme dite: L'OREALInventors: Jean-Francois Grollier, Josiane Allec, Chantal Fourcadier, Georges Rosenbaum, Patrick Darmenton
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Patent number: 4921874Abstract: There is described a medicinal bath oil containing about 68-95 percent by weight of one or more physiologically acceptable oil and about 30-5 percent by weight of one or more physiologically acceptable emulsifiers, at least one of which is a fatty alcohol polygolyol ether.Type: GrantFiled: August 17, 1987Date of Patent: May 1, 1990Assignee: Merck Patent Gesellschaft mit Beschrankter HaftungInventors: Rolf Franke, Peter Schmersahl
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Patent number: 4913896Abstract: A talc-base body powder composition having an unique composition of desirable characteristics including moisture absorbency, anti-ammonia, anti-bacterial and anti-fungal effects making it specially useful for infant skin care purposes consisting essentially of talc, cornstarch, calcium undeclyenate and citric or ascorbic acid in critical proportions.Type: GrantFiled: February 22, 1988Date of Patent: April 3, 1990Inventor: Norman A. Harvey
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Patent number: 4857321Abstract: A skin ointment, comprising about twelve (12%) percent by volume mink oil; about nine (9%) percent by volume lanolin; about four (4%) percent by volume zinc stearate; about four (4%) percent by volume octylmethoxycinnamate; about four (4%) percent by volume methylgluceth--10; about four (4%) by volume peg 100 stearate; about three (3%) percent by volume cetal; about three (3%) percent by volume peanut oil; about two (2%) percent glyceral monostrearate; about two (2%) percent acetylated lanolin alcohol; about one (1%) percent spermaceti; about one (1%) percent propylene glycol; about one (1%) percent panthenol; less than one (1%) percent tocopheryl acetate; and, about forty-seven (47%) percent by volume water.Type: GrantFiled: August 26, 1988Date of Patent: August 15, 1989Inventor: William C. Thomas
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Patent number: 4816254Abstract: The invention provides an ointment composition for treating skin irritations such as diaper rash and decubitus. The composition includes zinc oxide, boric acid, karaya gum, peruvian balsam, cod liver oil and an appropriate solvent and pharmaceutical carrier.Type: GrantFiled: July 29, 1987Date of Patent: March 28, 1989Inventor: Thomas D. Moss
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Patent number: 4738956Abstract: A new and improved topically applied pharmaceutical preparation for the treatment of itching, rash, eczema, insect bites, poison ivy and the like and an improved vehicle for delivering the active ingredients thereof to the human skin in a manner whereby the bioavailability and percutaneous absorption of the active ingredient is remarkably enhanced. The vehicle comprises a volatile silicone, a fatty alcohol having from 12-22 carbon atoms, hydrocortisone; and such preservatives or emulsifying agents as may be warranted.Type: GrantFiled: December 15, 1986Date of Patent: April 19, 1988Assignee: Neutrogena CorporationInventors: Richard A. Scott, Mitchell S. Wortzman, Eric Jungermann
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Patent number: 4556560Abstract: Methods for the treatment and prevention of diaper rash and diaper dermatitis caused by the prolonged contact of human skin with body waste are disclosed. The methods of the present invention employ the topical application of a minimum inhibitory concentration of a pharmaceutically-acceptable lipase-inhibiting agent to the area in need of such treatment, or the area where prevention is desired. The lipase-inhibiting agent is preferably a water-soluble metallic salt, such as ZnCl.sub.2, and is preferably applied in combination with a barrier-like vehicle. The effectiveness of these methods is surprising in light of the present confusion and controversy surrounding the actual causes of diaper rash, and the heretofore unrecognized role of lipase as a factor in the cause of diaper rash and diaper dermatitis.Type: GrantFiled: January 24, 1983Date of Patent: December 3, 1985Assignee: The Procter & Gamble CompanyInventor: Kent W. Buckingham