Abstract: Novel pharmaceutical solutions and particularly novel pharmaceutical solutions comprising dimethyl sulfoxide (DMSO).

Abstract: The invention concerns a composition, i.e., a multifunctional medically active agent for rational therapy of malignant (cancerous) diseases based on cause-and-effect relationship. The new composition according to the invention contains dimethylsulfoxide, DMSO, or sulfolan, preferably DMSO, in combination with a therapeutically effective amount of at least one cytostatic agent. The invention also concerns a method for treatment of malignant (cancerous) conditions in man comprising local or systemic administration thereto of an effective dosage of the composition according to the invention.The invention surprisingly provides a composition, as well as a method of treatment, allowing rational specific or selective carcinostatic-carcinocidic therapy. This therapy-form aims at the intracytoplasmic 3-dimensional cytoskeleton (differentiation organelle) that is specifically changed in the malignant cells, as well as at the targets responsible for karyokinesis and cytokinesis.

Abstract: A synthetic resin wound dressing (e.g., a burn wound dressing) is disclosed consisting essentially of a polymer, such as poly(2-hydroxyethylmethacrylate), referred to as PHEMA, an organic solvent, such as polyethylene glycol (PEG), and a hydrogen binding plasticizer, such as dimethylsulfoxide (DMSO). The plasticizer regulates the set-up time of the synthetic resin so that the more plasticizer present, the shorter the set-up time. The dressing may be applied to the wound site in the form of a paste for the in situ curing or setting thereof, or the dressing may be preformed and then applied to the wound site. A variety of drug agents (e.g., silver sulfadiazine) may be incorporated in the synthetic resin so as to result in the time released administration of the drug agent to the area of the skin (e.g., a burn wound site or the like) covered by the wound dressing. A method of treatment using this dressing is also disclosed.

Abstract: A microencapsulated agricultural chemical comprises an agricultural chemical as an active ingredient having a solubility of not more than 1 g in 100 ml of water at 20.degree. C. and vapor pressure of not more than 760 mmHg at 60.degree. C. and a microcapsule wall enclosing the agricultural chemical therein and the microcapsule wall comprises a water-soluble cationic urea resin and at least one of prepolymer composed of formaldehyde and at least one compound selected from the group consisting of urea, melamine and thiourea. The microcapsule is prepared by dispersing the agricultural chemical in an aqueous medium containing the water-soluble cationic urea resin, an anionic surfactant and at least one of the prepolymer and maintaining pH of the obtained dispersion within an acidic range to polycondense the water-soluble cationic urea resin and at least one of the prepolymers.