Gel Patents (Class 514/944)
  • Patent number: 10660945
    Abstract: A flowable hemostatic gel composition is provided for use at a site of a defect within a biological tissue. The flowable hemostatic gel composition includes a flowable gel solution that includes a biopolymer dissolved in a first solvent. The biopolymer is configured to cross-link with red blood cells at the site to facilitate clot formation at the site. The flowable hemostatic gel composition also includes at least one additional active agent.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: May 26, 2020
    Inventor: Victor Matthew Phillips
  • Patent number: 9180146
    Abstract: The subject patent application relates to a skin salve which is comprised of (1) petrolatum, (2) beeswax, and (3) peppermint oil, wherein the beeswax is present in said salve at a level of at least 11 weight percent. The present invention also discloses a method for treating irritated skin which comprises topically applying a skin salve to the irritated skin, wherein the skin salve is comprised of (1) petrolatum, (2) beeswax, and (3) peppermint oil, wherein the beeswax is present in said salve at a level of at least 11 weight percent.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: November 10, 2015
    Inventor: Teresa D. Carter
  • Patent number: 9012521
    Abstract: An object of the present invention is to provide a gel containing pyrroloquinoline quinone that is capable of easily forming a gel near room temperature and is useful even in the food sector, and a method for producing the gel. According to the present invention, there is provided a gel containing pyrroloquinoline quinone that uses pyrroloquinoline quinone itself as a gelling agent and a method for producing the gel by adding a salt of pyrroloquinoline quinone to water and subsequently adjusting the temperature or the pH to reduce solubility.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: April 21, 2015
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Tsuyoshi Mikekado, Kazuto Ikemoto, Hajime Shimizu
  • Patent number: 8952057
    Abstract: Compositions containing polymetal complexes are useful in treating anorectal disorders.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: February 10, 2015
    Assignee: JR Chem, LLC
    Inventor: José E. Ramirez
  • Patent number: 8951553
    Abstract: A composition for topical application to a part of the body comprises a vasodilator, for example glyceryl trinitrate, as active ingredient dissolved in a blend of volatile and non-volatile solvents of different solvating capacities for the vasodilator. The vasoldator is present in the composition at a concentration at or slightly below saturation, whereby evaporation of the volatile solvent in use will maintain the vasodilator at saturated or super-saturated concentrations in the residue, whereby the vasodilator will become saturated or supersaturated in the solvent remaining and, as the active ingredient passes through the skin and is absorbed in the bloodstream, and thus becomes depleted in the residual composition, continuing evaporation of volatile solvent will maintain the active ingredient substantially at saturation or supersaturation level in the residual composition throughout the major part of the absorption phase, thereby maximising absorption levels but at a moderate dosage level.
    Type: Grant
    Filed: August 8, 2005
    Date of Patent: February 10, 2015
    Assignee: Futura Medical Developments Limited Surrey Technology Centre
    Inventor: Adrian Francis Davis
  • Patent number: 8936778
    Abstract: Composition and methods include a dental bleaching agent, potassium nitrate a fluoride salt for enhanced whitening and reduced tooth sensitivity. The potassium nitrate and fluoride salt both reduce or eliminate tooth sensitivity that may otherwise be caused by the bleaching agent. For prolonged treatment of teeth, lower quantities of potassium nitrate (e.g., 0.5%) have actually been found to work better than larger quantities (e.g., 3%). The dental compositions may be applied directly to the person's teeth, or they may be loaded into a comfortable fitting, flexible, thin-walled dental tray and placed over the person's teeth. In that case, the dental compositions will include a tackifying agent, such as carboxypolymethylene, which assists the composition in retaining the dental tray over the person's teeth as a result of the adhesive properties of the dental composition rather than due to mechanical interlocking of the tray over the person's teeth.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: January 20, 2015
    Assignee: Ultradent Products, Inc.
    Inventor: Dan E. Fischer
  • Patent number: 8883767
    Abstract: A low ether gel composition for application to skin comprising a keratolytic agent, in particular salicylic acid, and comprising a nitrocellulose and one or more volatile ingredients, which forms a film on contact with skin adequate to form a protective barrier for the keratolytic agent for a period of time necessary to provide treatment to the skin; methods of treating using such compositions, and dispensers containing such compositions.
    Type: Grant
    Filed: October 4, 2010
    Date of Patent: November 11, 2014
    Assignee: MSD Consumer Care, Inc.
    Inventors: Gerald R. Dever, Eric Chen-nan Su, William Scott Rogersr, Robert C. Johnson
  • Patent number: 8846646
    Abstract: The invention relates to an unexpected discovery that propylene glycol is highly effective at killing or inhibiting Propionibacterium acnes in a mammalian skin disorder, as well as to the use of propylene glycol and salicylic acid in a skin-disorder treatment. This invention also relates to compositions containing propylene glycol alone or in combination with salicylic acid for use in killing or inhibiting Propionibacterium acnes.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: September 30, 2014
    Assignee: Winlind Skincare, LLC
    Inventor: Win L Chiou
  • Patent number: 8802626
    Abstract: Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with enhanced stability using less osteogenic protein than devices in the art. Defects susceptible to repair with the instant invention include, but are not limited to: critical size defects, non-critical size defects, non-union fractures, fractures, osteochondral defects, subchondral defects, and detects resulting from degenerative diseases such as osteochondritis dessicans.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: August 12, 2014
    Assignee: Stryker Corporation
    Inventors: David C. Rueger, Marjorie M. Tucker, An-Cheng Chang
  • Patent number: 8747821
    Abstract: The invention relates to a clear, cosmetic and dermatological formulation having reduced stickiness, comprising at least one antiperspirant active ingredient and/or deodorant active ingredient, at least one ?-hydroxycarboxylic acid and water.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: June 10, 2014
    Assignee: Beiersdorf AG
    Inventors: Ulrike Schulz, Gordon Christ
  • Patent number: 8735393
    Abstract: The present invention provides anhydrous compositions for topical delivery of a medicament comprising (A) a penetration enhancer/solvent selected from the group consisting of alcohol, propylene glycol, or a combination thereof; (B) a humectant/solvent selected from the group consisting of polyethylene glycol, glycerin, sorbitol, xylitol, or any combination of any of the foregoing; and (C) an anhydrous vehicle. In an alternate embodiment, the present invention provides anhydrous compositions for topical delivery of a medicament which comprise (A) a penetration enhancer/solvent selected from the group consisting of alcohol, propylene glycol, or a combination thereof; (B) a humectant/solvent selected from the group consisting of polyethylene glycol, glycerin, sorbitol, xylitol or any combination of any of the foregoing; (C) an anhydrous vehicle; and (D) a medicament. Also provided are methods for topically delivering a medicament to an animal.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: May 27, 2014
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Katherine M. Burnett, Ellen S. Kurtz
  • Patent number: 8729235
    Abstract: The invention provides an isolated major ampullate spidroin protein, which consists of from 150 to 420 amino acid residues and is defined by the formula REP-CT. REP is a repetitive, N-terminally derived protein fragment having from 80 to 300 amino acid residues. CT is a C-terminally derived protein fragment having from 70 to 120 amino acid residues. The invention further provides an isolated fusion protein consisting of a first protein fragment, which is a major ampullate spidroin protein, and a second protein fragment comprising a fusion partner and a cleavage agent recognition site. The first protein fragment is coupled via said cleavage agent recognition site to the fusion partner. The invention also provides a method of producing a major ampullate spidroin protein and polymers thereof.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: May 20, 2014
    Assignee: Spiber Technologies AB
    Inventors: Jan Johansson, Gäran Hjäm, Margareta Stark, Anna Rising, Stefan Grip, Wilhelm Engsträm, My Hedhammar
  • Patent number: 8722024
    Abstract: Gels of isopropyl esters of fatty alcohols that include a dimethyl/methylhydrogensiloxane copolymer, a silanol-terminated PDMS or an ethenyl-terminated PDMS, and a hydride functional siloxane. Also provided are methods for making the gels and articles containing them.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: May 13, 2014
    Assignee: Jeen International Corporation
    Inventors: Juan Mateu, Adam Perle
  • Patent number: 8709454
    Abstract: At least one phytosphingosine salicylate derivative and at least one lysate of at least one microorganism of the genus Bifidobacterium. Composition, combination. Use, including cosmetic use for reinforcing the repair and regeneration capacity of an epithelium, especially an epidermis, in particular an aged epidermis.
    Type: Grant
    Filed: January 12, 2010
    Date of Patent: April 29, 2014
    Assignee: L'Oreal
    Inventors: David Amar, Bruno Bernard, Dominique Bernard, Isabelle Castiel
  • Patent number: 8709385
    Abstract: Pharmaceutical or cosmetic compositions and methods for their use are provided comprising water and a surfactant polymer system comprising a Poloxamer at a concentration of about 0.1% to about 15% by weight; wherein when the Poloxamer is between about 0.1% to about 5% Poloxamer. The composition can further comprise a supporting agent comprising a non-ionic surface active agent or a supporting agent comprising a non surfactant polymer or polysaccharide and an active agent, where the Poloxamer is capable of fixing the composition on delivery to a body surface. There are further provided therapeutic cell compositions and their uses.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: April 29, 2014
    Assignee: Foamix Ltd.
    Inventors: Dov Tamarkin, Alex Besonov, Tal Berman, David Schuz, Elana Gazal
  • Patent number: 8703195
    Abstract: Disclosed is a method in which poloxamer, a resin, and/or a tocopherol is/are fused, and the material that is to be treated is intimately dispersed with said melt. After being introduced into the melt, the material that is to be treated is coated with water to prevent hardening, and the spontaneously forming gel is homogenized. The obtained product is composed of a transparent gel that is based on at least one poloxamer, a resin or a tocopherol, and an active substance which is solubilized, dispersed, and stabilized therein and whose consistency ranges from solid, semisolid, i.e. aspic-like, to liquid. The micelles of said solubilized matter remain stable even when the same is diluted well below the CMC of poloxamer.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: April 22, 2014
    Assignee: Biorem AG
    Inventor: Hanspeter Strobel
  • Patent number: 8632823
    Abstract: Super-oxidized water based on hypochlorous acid, such as is obtained by the electrochemical treatment of a saline solution, may be used in the treatment of leg ulcers or other open wounds. Preferably, the pH of the super-oxidized water is in a range of 4 to 7, and the water has a redox potential of >950 mV. Medicaments based on the super-oxidized water may be in liquid or gel form. The super-oxidized water is able to control the microbial population within the wound and at the same time permit cell proliferation.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: January 21, 2014
    Assignee: Puricore, Inc.
    Inventor: Joe B. Selkon
  • Patent number: 8617524
    Abstract: A cosmetic regime or regimen for depigmenting, lightening and/or bleaching keratin materials, especially the skin, entails topically applying thereon a cosmetic composition containing a dithiolane compound of formula (I): in which: Y is O, NR1 or S R1 is a hydrogen atom; a C1-C20 alkyl radical or an optionally substituted phenyl radical; R is a hydrogen atom; or a C1-C20 alkyl radical, or an optionally substituted phenyl radical, or a C1-C8 alkyl radical containing an optionally substituted phenyl substituent; n=0 or 1 or 2; and also the salts, chelates, solvates and optical isomers thereof.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: December 31, 2013
    Assignee: L'Oreal
    Inventors: Xavier Marat, Karine Lucet-Levannier, Laurent Marrot
  • Patent number: 8618175
    Abstract: Ultrasound medical gel composition, the compositions comprising: (a) a gelling agent comprising etherified hydroxyethylcellulose; (b) an antimicrobial agent, specifically the quaternary ammonium compound benzalkonium chloride; (c) a solvent, 1,3-propanediol being preferred; and (d) water.
    Type: Grant
    Filed: July 18, 2011
    Date of Patent: December 31, 2013
    Assignee: Brussels Ventures Corp.
    Inventor: Thomas Heinar
  • Patent number: 8551504
    Abstract: Topically applicable compositions in the form of oil-in-water emulsions contain a pro-penetrating system including at least one glycol and at least one additional pro-penetrating agent, a suitable gelling agent and at least one active agent of the family of steroidal anti-inflammatory agents and are useful, e.g., for the treatment of psoriasis.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: October 8, 2013
    Assignee: Galderma S.A.
    Inventors: Sandrine Segura-Orsoni, Sophie Roumec
  • Patent number: 8545832
    Abstract: The present invention relates to pre-formulations comprising low viscosity, non-liquid crystalline, mixtures of: a) at least one neutral diacyl lipid and/or at least one tocopherol; b) at least one phospholipid; c) at least one biocompatible, oxygen containing, low viscosity organic solvent; wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The preformulations are suitable for generating parenteral, non-parenteral and topical depot compositions for sustained release of active agents. The invention additionally relates to a method of delivery of an active agent comprising administration of a preformulation of the invention, a method of treatment comprising administration of a preformulation of the invention and the use of a preformulation of the invention in a method for the manufacture of a medicament.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: October 1, 2013
    Assignee: Camarus AB
    Inventors: Krister Thuresson, Fredrik Tiberg, Markus Johansson, Ian Harwigsson, Fredrik Joabsson, Markus Johnsson
  • Patent number: 8535653
    Abstract: An article for sequential dispensing of vapors, notably evaporable fragrances, comprises separated first and second liquids (22, 24). Liquid (22) issues first. Its evaporation may be assisted by a wick (26). The simultaneous evaporation of the second liquid is prevented by an intermediate liquid phase (20). As liquid (22) issues the liquid levels change and there comes a point at which the intermediate phase can no longer prevent the second liquid (24) from flowing past it, to the region from which it can be evaporated. Solids, especially gels, may be employed instead of liquids (22, 24).
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: September 17, 2013
    Assignee: Reckitt Benckiser (UK) Limited
    Inventor: Malcolm Tom McKechnie
  • Patent number: 8524271
    Abstract: A skin wound dressing is disclosed. The skin wound dressing comprises Tremella polysaccharide and alginate and is used to cover on a skin wound to accelerate wound healing. The Tremella polysaccharide is isolated from a hot water extract of Tremella fuciformis. The skin wound dressing is a Tremella polysaccharide composite fiber, a Tremella polysaccharide sponge or a Tremella polysaccharide hydrogel.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: September 3, 2013
    Assignee: Agricultural Research Institute
    Inventor: Shu-Hui Yang
  • Patent number: 8513225
    Abstract: Disclosed herein is a composition containing a high concentration of PG is unexpectedly capable of quickly killing other bacteria, fungi, and/or virus in vitro that is indicative of its potential high efficacy in treating various skin infection. Embodiments disclosed herein relate to a composition and method for effective topical treatment of inflammatory skin lesions in mammals, comprising of a high concentration of propylene glycol alone, or in combination with an astringent. The PG at high concentrations can be regarded as an extremely effective, safe, topical, universal, microbicide.
    Type: Grant
    Filed: April 5, 2011
    Date of Patent: August 20, 2013
    Assignee: Winlind Skincare, LLC
    Inventor: Win L Chiou
  • Patent number: 8492366
    Abstract: The solubility in solvent media, notably alcoholic media, of the beta-hydroxy acids (“BHAs”), notably the chemical skin peeling agent salicylic acid, is markedly enhanced by solubilizing same in the presence of at least one alpha-hydroxy acid (“AHA”); higher potency, more concentrated BHA skin peel products are thus formulated.
    Type: Grant
    Filed: February 26, 2003
    Date of Patent: July 23, 2013
    Assignee: Societe L'Oreal S.A.
    Inventors: Marc Cornell, Hani Fares, Sidney Peter Foltis, Isabelle Hansenne
  • Patent number: 8486377
    Abstract: A composition of matter and a method are disclosed including mixing pieces of solid beeswax and liquid jojoba wax at a predetermined temperature within a predetermined range of temperatures, filtering the mixture, and cooling the mixture to form a colloidal gel.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: July 16, 2013
    Inventor: Michael Joseph Wrenn
  • Patent number: 8475770
    Abstract: The present subject matter provides foamable suspension gels that foam after release from a container. The foamable suspension gels contain at least one pharmaceutically active agent that is sparingly soluble to insoluble in water, a second pharmaceutically active agent, and optionally a third active agent.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: July 2, 2013
    Assignee: Stiefel Research Australia Pty Ltd
    Inventors: Albert Zorko Abram, Lilian Fuchshuber
  • Patent number: 8470881
    Abstract: The present application discloses a system for trapping flying insects, a first chemical lure such as lactic acid, a salt of lactic acid, or combinations thereof, and a second chemical lure comprising a source of ammonia. The lures may be employed in particular geometric shapes contained in specifically designed housing to ensure an effective release rate over extended periods of time.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: June 25, 2013
    Assignee: Woodstream Corporation
    Inventors: Emma A Durand, Miaoyong Cao, Cuixia Liu, Richard B. Dunne
  • Patent number: 8465763
    Abstract: The present invention relates to the use of 3?-hydroxychlormadinone acetate (17?-acetoxychloropregna-4,6-dien-3?-ol-20-one) and/or 3?-hydroxychlormadinone acetate (17?-acetoxychloropregna-4,6-dien-3?-ol-20-one) for producing a medicament for treating skin, preferably human skin by means of topical application, and to a pharmaceutical or cosmetic composition containing 3?-hydroxychlormadinone acetate and/or 3?-hydroxychlormadinone acetate.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: June 18, 2013
    Assignee: Richter Gedeon Nyrt.
    Inventors: Georg Schramm, Christa Kneip
  • Patent number: 8436050
    Abstract: Antimicrobial compositions having synergistic combinations of octoxyglycerin and at least one other antimicrobial agent in formulations which are more effective than prior art compositions without causing increased irritation to the skin of the average user. In certain embodiments, skin irritation may be minimized by low concentrations of antimicrobials and/or the presence of soothing compounds such as zinc. Preferred embodiments include combinations of octoxyglycerin, a quaternary compound, and at least one other antimicrobial agent. Without being bound to any particular theory, it is hypothesized that the unexpected antimicrobial effectiveness of combinations of octoxyglycerin may result from an enhancement of the permeability of microbes to antimicrobials caused by octoxyglycerin. Hydroalcoholic gel composition containing alcohol, water, hydrogel, and emollient or emulsifier, wherein the composition has a viscosity of below 2000 centipoises at between 20 and 40° C.
    Type: Grant
    Filed: February 24, 2004
    Date of Patent: May 7, 2013
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Shanta Modak, Trupti A. Gaonkar, Lauser Caraos, Lester Sampath
  • Patent number: 8388978
    Abstract: A topical skin care composition and method for its use comprising water, Chlorella vulgaris extract, an algae extract, a phospholipid or lecithin, glycerin, retinyl palmitate, tocopheryl acetate, and magnesium ascorbyl phosphate.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: March 5, 2013
    Assignee: Mary Kay Inc.
    Inventor: Gopa Majmudar
  • Patent number: 8372805
    Abstract: Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with enhanced stability using less osteogenic protein than devices in the art. Defects susceptible to repair with the instant invention include, but are not limited to: critical size defects, non-critical size defects, non-union fractures, fractures, osteochondral defects, subchondral defects, and defects resulting from degenerative diseases such as osteochondritis dessicans.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: February 12, 2013
    Assignee: Stryker Corporation
    Inventors: David C. Rueger, Marjorie M. Tucker, An-Cheng Chang
  • Patent number: 8323629
    Abstract: An external preparation for skin has a pH value of 2.0-5.0 and comprises: (a) 1.0-7.0 mass % of at least one of the members selected from ?-hydroxy acids, (b) 0.1-3.0 mass % of a crosslinked type N,N-dimethylacrylamide-2-acrylamido-2-methylpropanesulfonic acid sodium salt copolymer, and (c) 0.1-3.0 mass % of an associating thickener constituted of a compound of the formula (1): R1—{(O—R2)k—OCONH—R3[—NHCOO—(R4—O)n—R5]h}m (1) wherein R1 represents a hydrocarbon group, R2 and R4 represent alkylene groups having 2-4 carbon atoms, which may be identical or different, or a phenylethylene group, R3 represents a hydrocarbon group, which may have a urethane bond, R5 represents a branched chain or secondary hydrocarbon group, m is a number of at least 2, h is a number of at least 1, k is a number within the range of 1-500, and n is a number within the range of 1-200.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: December 4, 2012
    Assignee: Shiseido Company, Ltd.
    Inventor: Naoki Tominaga
  • Patent number: 8252308
    Abstract: The present invention provides a substantially clear gel designed to reduce itching discomfort when applied to the vulvar tissue. The gel includes at least one anesthetic, protectant, emulsifier, and pH modifier, such as a base. The gel has a pH adapted to vulvar use and may be applied to the vulvar tissues.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: August 28, 2012
    Assignee: C.B. Fleet Company Inc.
    Inventors: Nelson Ayala, Michael L. Caswell
  • Patent number: 8241612
    Abstract: A composition of matter and a method are disclosed including mixing pieces of solid beeswax and liquid jojoba wax at a predetermined temperature within a predetermined range of temperatures, filtering the mixture, and cooling the mixture to form a colloidal gel.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: August 14, 2012
    Inventor: Michael Joseph Wrenn
  • Patent number: 8236864
    Abstract: Fluids viscosified with viscoelastic surfactants (VESs) may have their viscosities affected (increased or reduced, e.g. gels broken) by the indirect or direct action of a composition that contains at least one fatty acid that has been affected, modified or reacted with an alkali metal base, an alkali earth metal base, ammonium base, and/or organic base compound, optionally with an alkali metal halide salt, an alkali earth metal halide salt, and/or an ammonium halide salt. The composition containing the resulting saponification product is believed to either act as a co-surfactant with the VES itself to increase viscosity and/or possibly by disaggregating or otherwise affecting the micellar structure of the VES-gelled fluid. In a specific, non-limiting instance, a brine fluid gelled with an amine oxide surfactant may have its viscosity broken with a composition containing naturally-occurring fatty acids in canola oil or corn oil affected with CaOH, MgOH, NaOH and the like.
    Type: Grant
    Filed: May 28, 2010
    Date of Patent: August 7, 2012
    Assignee: Baker Hughes Incorporated
    Inventor: James B. Crews
  • Patent number: 8232276
    Abstract: The present invention provides anhydrous compositions for topical delivery of a medicament comprising (A) a penetration enhancer/solvent selected from the group consisting of alcohol, propylene glycol, or a combination thereof; (B) a humectant/solvent selected from the group consisting of polyethylene glycol, glycerin, sorbitol, xylitol, or any combination of any of the foregoing; and (C) an anhydrous vehicle. In an alternate embodiment, the present invention provides anhydrous compositions for topical delivery of a medicament which comprise (A) a penetration enhancer/solvent selected from the group consisting of alcohol, propylene glycol, or a combination thereof; (B) a humectant/solvent selected from the group consisting of polyethylene glycol, glycerin, sorbitol, xylitol or any combination of any of the foregoing; (C) an anhydrous vehicle; and (D) a medicament.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: July 31, 2012
    Assignee: Johnson & Johnson Comsumer Companies, Inc.
    Inventors: Katherine M. Burnett, Ellen S. Kurtz
  • Patent number: 8221802
    Abstract: A unique, synergistic formulation for the treatment of first-degree skin burns is provided for topical use and alleviates the full spectrum of symptoms and concerns associated with epidermal burns, including pain, blistering, redness, swelling, compromised skin integrity, risk of infection and scarring. The formulation contains natural homeopathic extracts combined with a pharmaceutically acceptable carrier suitable for topical administration. The formulation may include three or more of the following homeopathic extracts: Cantharis Vesicatoria, Echinacea Angustifolia, Calendula Officinalis and Hypericum Perforatum.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: July 17, 2012
    Assignee: The Akshay Wellness Group, Inc.
    Inventor: Sai S. Manickam
  • Patent number: 8202548
    Abstract: A method of making a composition having the property of being able to store chlorine dioxide includes mixing an aqueous chlorine dioxide solution with a superabsorbent, water-soluble polymer that is substantially unreactive with chlorine dioxide and permitting a mixture formed thereby to form one of a gel and a solid composition. A method of delivering chlorine dioxide includes providing a gel or solid composition as described and degelling the gel or dissolving the solid composition to dispense the chlorine dioxide therefrom. A method of disinfecting a target such as water, wastewater, or a surface comprises delivering chlorine dioxide as above and permitting the polymer to precipitate out of the mixture. Aqueous chlorine dioxide is then recovered and applied to the target.
    Type: Grant
    Filed: July 19, 2007
    Date of Patent: June 19, 2012
    Assignee: Dharma IP, LLC
    Inventors: Sunggyu Lee, Patricia Roberts
  • Patent number: 8192751
    Abstract: A bone grafting material composite is provided. The bone grafting material composite includes a demineralized bone matrix (DBM) and a carboxymethyl cellulose (CMC)/glycerol gel carrier. Due to the CMC/glycerol gel carrier, the implantation ability thereof is better than that of the DBM. Therefore, the bone grafting material composite can be easily used, so that a curative effect can be greatly improved. In addition, since the CMC/glycerol gel is used as a carrier, the composite with a mobility maintained is washed out by water after surgery, so that the composite can be fixed on a damaged portion of a bone.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: June 5, 2012
    Assignee: Hans Biomed.Cor
    Inventors: Jin-Young Kim, Jae-Hyoung Ahn, Seok-Beam Song, Ji-Hwa Chae, Seog-Jin Seo, Ke-Won Kang, Ho-Chan Hwang, Jung-Suk Lee
  • Patent number: 8178115
    Abstract: A multi-component medicament composition for the treatment of scars comprising a combination of a steroid and silicone.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: May 15, 2012
    Inventor: Joel R. Studin
  • Patent number: 8142808
    Abstract: Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment between biomaterials and living tissues are provided. Also provided are implants suitable for load-bearing surfaces in hard tissue repair, replacement, or augmentation, and to methods of their use. One embodiment of the invention relates to an implantable spinal disc prosthesis.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: March 27, 2012
    Assignee: Georgia Tech Research Corporation
    Inventors: Barbara D. Boyan, Stephen J. Kennedy, Zvi Schwartz
  • Patent number: 8114855
    Abstract: Low density cosmetic formulations which comprise: (a) a cosmetic mixture; and (b) a gas incorporated in the cosmetic mixture; wherein the cosmetic mixture comprises (i) an alk(en)ylpolyglycoside, (ii) a quaternary ammonium polymer, and (iii) a thickener, are described along with suitable cosmetic mixtures for forming such low density formulations, methods of forming such formulations and methods of treating skin, hair, nails and/or combinations thereof by contacting the skin, hair and/or nails with such formulations and/or products containing such formulations.
    Type: Grant
    Filed: November 21, 2007
    Date of Patent: February 14, 2012
    Assignee: L'Oreal
    Inventors: Jim M. Singer, Jolene A. Morris
  • Patent number: 8101196
    Abstract: The invention includes a medical hydrogel made from polymerized polysaccharide macromers. The macromers are preferably polysaccharides decorated with polymerizable groups, for example, methacrylates. The macromers may also be made into polymers of at least two macromers polymerized together. These polymers are preferably multi-armed or high-molecular weight and used for medical uses, for example, making coatings on medical devices. Macromers of N-vinylpyrrolidone are also disclosed herein.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: January 24, 2012
    Assignee: BioInteractions, Ltd.
    Inventors: Ajay K. Luthra, Shivpal S. Sandhu, John O. Hudson
  • Patent number: 8097262
    Abstract: An enteral nutrient gel that is excellent at maintaining its solid matter (gel) form in the stomach, does not readily disintegrate or dissolve with a change in pH, is stable in its physical properties even during long-term storage, and can be passed through a feeding tube. The enteral nutrient gel contains agar, alginic acid and/or a salt thereof, soybean protein or a hydrolysate thereof, calcium, magnesium, dextrin, and, optionally, an oligosaccharide, a disaccharide and/or a monosaccharide. A solid composition containing 8 to 30 wt % protein, 2 to 25 wt % fats, and 40 to 70 wt % dextrin is used in preparing the enteral nutrient gel.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: January 17, 2012
    Assignee: En Otsuka Pharmaceutical Co., Ltd.
    Inventors: Minoru Kuribayashi, Yasunori Kogami
  • Patent number: 8067469
    Abstract: The present application discloses a system for trapping flying insects, a first chemical lure such as lactic acid, a salt of lactic acid, or combinations thereof, and a second chemical lure comprising a source of ammonia. The lures may be employed in particular geometric shapes contained in specifically designed housing to ensure an effective release rate over extended periods of time.
    Type: Grant
    Filed: June 8, 2004
    Date of Patent: November 29, 2011
    Assignee: Woodstream Corporation
    Inventors: Emma A Durand, Miao-Yong Cao, Cuixia Liu, Richard B. Dunne
  • Patent number: 8052984
    Abstract: The invention is an increased effectiveness of allylamine drug compounds for topical treatment of fungal infections of skin and skin appendages. The allylamine active ingredient is prepared in an acidic environment; the acidic environment altering the physiochemical properties of the active ingredient resulting in the active ingredient having a positive charge. The positive charge and enhancers used in the formula allow for increased penetration of the active ingredient through skin and skin appendages. The positively charged active ingredients are either dissolved in the vehicle directly or dissolved in a plurality of beads suspended in the vehicle.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: November 8, 2011
    Assignee: Biophile Corporation, Ltd.
    Inventors: Pichit Suvanprakorn, Panida Vayumhasuwan, Nardo Zaias
  • Patent number: 8025651
    Abstract: A urinary anti-backflow device is provided which prevents urine from flowing back into the patient's bladder from a urine collection bag. The device comprises a flow tube having an upstream section connectable to an external urinary device secured to a patient and a downstream section connectable to a urine collection bag, a rod within the flow tube, and a stopper which moves along the rod between the downstream and upstream ends of the flow tube. When the upstream section of the flow tube is elevated relative to the downstream section, urine from the patient is free to flow through the flow tube. When the downstream section of the flow tube is elevated relative to the upstream section, urine forces the stopper against the upstream section to prevent backflow.
    Type: Grant
    Filed: March 17, 2009
    Date of Patent: September 27, 2011
    Inventor: Carl Hart
  • Patent number: 8021683
    Abstract: A composition comprising a non-volatile silicone fluid in admixture with fumed silica, a volatile diluent and a silicone elastomer.
    Type: Grant
    Filed: July 16, 2003
    Date of Patent: September 20, 2011
    Assignee: Advanced Bio-Technologies, Inc.
    Inventor: Alvin Berlat
  • Patent number: 7989003
    Abstract: A viscous gel for delivering minor effective amounts of active substances through the nasal membrane into the body.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: August 2, 2011
    Assignee: Zicam, LLC
    Inventors: Charles Hensley, Robert Steven Davidson