Abstract: An aerosol composition which is prepared from a biliquid foam, an aqueous phase and a propellant, and wherein an oil soluble functional material is incorporated into the biliquid foam during preparation to enable this material to be more readily incorporated into the composition. The aerosol composition can be contained in a pressurized aerosol can and can be a polish, an air freshener, a repellant. a pre- or post-shave preparation, a shaving preparation or a follicle softener.

Abstract: Polyethylene glycol ethers of alkyl alcohols having the general formula CH3(CH2)xCH2(OCH2CH2)nOH wherein x is 8 to 20 (of which ceteareth-20, steareth-20 and steareth-100 are preferred), poloxamer 185, poloxamer 407, N,N-dimethyl dodecylamine N-oxide, and mixtures thereof, are employed to increase follicular delivery and/or follicular residence time of certain water soluble ornithine decarboxylase inhibitors of which 2(difluoromethyl)-2,5-diamino pentanoic acid and its pharmaceutically acceptable salts, hydrates, optical enantiomers and racemic mixture are preferred.

Abstract: Improved therapeutic sclerosing microfoams and methods and devices for making them are provided that have advantage in producing a consistent profile injectable foam with minimal input by the physician yet using high volume percentages of blood dispersible gases, thus avoiding use of potentially hazardous amounts of nitrogen.

Abstract: A self-reversible reverse microlatex composition comprising an oil phase, an aqueous phase, at least one W/O surfactant, at least one O/W surfactant, and a branched or a crosslinked polyelectrolyte, wherein the W/O surfactant and the O/W surfactant mixture have a HLB from about 9.5 to about 10, and the polyelectrolyte is either a homopolymer or copolymer or a combination thereof based on at least one monomer containing a strong or weak acid function. Further, the composition may be used in the cosmetic, dermopharmaceutical, pharmaceutical, textile, paper, and/or paint industries, or as a thickener for printing pastes based on pigments or dyes.

Abstract: The invention concerns the use in a cosmetic composition of at least a poly-aminoacid of general formula (I) in which X is —O—, —S— or —NR3; R1 represents in particular a hydrogen atom or a C1-C40 alkyl radical; R2 represents in particular a hydrogen atom or an optionally substituted alkyl radical; R3 represents a hydrogen atom or an alkyl radical; R4 represents a hydrogen atom or a radical such as NH2, OH, SH, —CHOHCH3, —CONH2; n is a number greater than 1 such that the poly-aminoacid derivative molecular weight ranges between 200 and 200000.

Abstract: Wound care devices having a topically applied silver-based antimicrobial finish are provided. The finish comprises at least one silver ion-containing compound and at least one binder compound. The finish may be applied to a target substrate, such as a fiber, fabric, film, foam, hydrogel, or hydrocolloid to provide a single layer antimicrobial wound care device. Alternatively, a silver-containing layer may be combined with one or more additional layers of target substrate to provide a composite antimicrobial wound care device. The device may also contain an odor-absorbing component capable of reducing or eliminating odors that are inherently associated with infectious wounds. Also provided is a method for making the wound care device and a composition of matter comprising the silver-based antimicrobial finish.

Abstract: The present patent describes a biocompatible composite made of a first fibrous layer attached to a three-dimensional inter-connected open cell porous foams that have a gradient in composition and/or microstructure through one or more directions. These composites can be made from blends of absorbable and biocompatible polymers. These biocompatible composites are particularly well suited to tissue engineering applications and can be designed to mimic tissue transition or interface zones.

Abstract: A system for delivering a chemical agent in the form of a spray or foam, which in a preferred embodiment involves the use of an aerosol dispenser to deliver a formulation containing both an anionic surface active agent such as sodium lauryl sulfate as a foaming agent and a chemical agent such as either hydrogen peroxide as a disinfecting chemical agent or natural sea water.

Abstract: An aerosol composition, which is prepared from a biliquid foam, an aqueous phase and a propellant. The incorporation of an oil soluble functional material into the biliquid foam during the preparation of the aerosol composition enables this material to be more readily incorporated into the composition.

Abstract: A topical mousse composition including an occlusive agent; an aqueous solvent; and an organic cosolvent, wherein the occlusive agent is present in an amount sufficient to form an occlusive layer on the skin.

Abstract: Improved therapeutic sclerosing microfoams are provided that have advantage in producing a consistent profile injectable foam with minimal input by the physician yet using high volume percentages of blood dispersible gases, thus avoiding use of potentially hazardous amounts of nitrogen.

Abstract: Stable aqueous dispersions of foaming surfactants are prepared by starting with a pre-formed substantially uniform surfactant composition which contains one or more foaming surfactants, and one or more fatty amphiphiles. The dispersion contains from 5 to 50 wt % of the surfactant composition and from 50 to 95 wt % water. A hydrocolloid is also preferably included in the dispersion. Emollients are also conveniently included in the aqueous dispersion.

Abstract: Disclosed are several preferred embodiments of hydrogen peroxide which are packaged with ease of use and extended shelf-life in mind. The embodiments include foam, mist, gel, and disposable towelette forms of H2O2. Optional ingredients of topical pain relievers and skin protectants are also disclosed, as are their methods of use.

Abstract: Improved therapeutic sclerosing microfoams and methods and devices for making them are provided that have advantage in producing a consistent profile injectable foam with minimal input by the physician yet using high volume percentages of blood dispersible gases, thus avoiding use of potentially hazardous amounts of nitrogen.

Abstract: The present invention relates to new silver-ion super-complex compositions. More particularly, the present invention describes silver-ion super-complex compositions comprising a silver-thiosulfate ion complex further complex with a primary, secondary or tertiary amine. These silver-ion super-complex compositions are stable in a saline environment and have improved solvent miscibility.

Abstract: An aqueous stable foam, suitable for use as a vaginal or hemorrhoidal wipe agent, containing at least one surfactant and at least one foam stabilizing agent can be dispensed to bathroom tissue or the like for application to the vaginal or anal area.

Abstract: The invention concerns a cosmetic composition comprising, in a cosmetically acceptable medium, at least a film-forming polymer (A) with particular characteristics and at least an additive (B), the latter being selected such that the film formed on the hair after the cosmetic composition has been applied retains its mechanical properties whatever the hygrometric condition. The invention also concerns a hair care or hair styling method using said composition and its use for the formulation of cosmetic products such as lacquers, sprays or foams, for hair care or hair styling.

Abstract: A pharmaceutical aerosol foam composition including an effective amount of a pharmaceutically active ingredient; an occlusive agent; an aqueous solvent; and an organic cosolvent, the pharmaceutically active ingredient being insoluble in both water and the occlusive agent; the occlusive agent being present in an amount sufficient to form an occlusive layer on the skin, in use.

Abstract: A cosmetic composition for slimming which includes, in combination with a cosmetically acceptable excipient, at least one compound having the formula (I) where R1 is a group bound by a peptidic bond and selected from the group consisting of a hydrogen atom, a hydroxyl group, an acyl group, acyloxy group and a substituted or unsubstituted aminoacid; R2 is a group bond by a peptidic bond and selected from the group consisting of a hydroxyl group, an amine group, an alkoxy group, an alkylamine group, a silyloxy group or a substituted or unsubstituted aminoacid; and n is 3 or 4.

Abstract: A carbon dioxide-containing viscous composition wherein carbon dioxide bubbles are retained in an aqueous viscous composition. Use of the composition makes it possible to treat or ameliorate itching accompanying mucocutaneous diseases or mucocutaneous disorders, mucocutaneous injury, dental diseases, skin ulcer, cryesthesia and numbness caused by peripheral circulatory disorders, musculoskeletal diseases, nervous system diseases, keratosis, constipation, unwanted hair re-growing after depilation, cosmetic troubles in the skin or hair, partial obesity, etc. while exerting little side effects.

Abstract: A method of conditioning and oxidatively dyeing human hair includes applying an oxidative hair dyeing composition to the human hair in order to dye the human hair and, simultaneously or subsequently to the applying of the oxidative hair dyeing composition, applying a particular hair conditioning composition to the hair. This hair conditioning composition has a pH value of from 3.4 to 3.9, which corresponds to an isoelectric point of the human hair, and contains from 0.001 to 2.5% by weight of a cationic polymer, an optional pH buffer and preferably additional conditioning ingredients, such as a cationic surfactant and/or a fatty alcohol.

Abstract: A foaming cosmetic product is provided packaged in a non-aerosol mechanical dispenser. The dispenser includes a container for holding a liquid composition, a dispensing head with a housing enclosing a pump mechanism and a screen material in the flow path to convert liquid composition into a foam, and a diptube for delivering liquid from the container to the dispensing head. The cosmetic composition is an opaque creamy, relatively non-viscous fluid, the creamy appearance imparted by a latex with suspended polymer particles compatible with the foaming mechanism.

Abstract: An absorbent foam material which comprises a solid, cross-linked form of an anionic polymer (e.g. an alginate) and fibers or other cation contributing polymeric particulates which have donated appropriate cations for effecting cross-linking of the anionic polymer. Methods of producing the foam material are also disclosed.

Abstract: Formulations have been developed for regional delivery of drugs, for example, into a cavity such as the pelvic region, peritoneal region, or directly on organs of interest. Regional delivery increases comfort and bioavailability of the drug, resulting in rapid and relatively high blood levels in the regions to be treated in the substantial absence of side effects due to the high levels required for efficacy following systemic delivery. In the preferred embodiment, these formulations consist of drug micro or nanoparticles, which may be formed of drug alone or in combination with an excipient or polymeric carrier. The excipient or polymer may be used to manipulate release rates and to increase adhesion to the affected region. The drug formulation can be applied as a dried powder, a liquid suspension or dispersion, or as a topical ointment, creme, lotion, foam or suppository.

Abstract: Disclosed are hair styling compositions which comprise from about 5% to about 90% by weight of a polyalkylene glycol styling agent that is substantially free of polyalkylene glyceryl ethers, and that has a number average molecular weight of from about 190 to about 1500 and from about 5 to about 35 repeating alkylene oxide radicals wherein each of the repeating alkylene oxide radicals has from 2 to 6 carbon atoms; from about 1% to about 90% by weight of a liquid carrier which can comprise water, an organic solvent, or combinations thereof; and, optionally, from about 5% to about 40% by weight of a propellant.

Abstract: Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thickeners has a viscosity of at least 4,000 centipoise at 23° C. and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.

Abstract: The wax product for treating or setting up a hairstyle or hairdo includes a composition containing at least one wax or wax-like substance, at least one non-volatile liquid hydrophobic oil and at least one volatile or easily volatilized hydrophobic substance that is a liquid or gas at room temperature. Because of the presence of the volatile substance in the composition a soft wax easily worked in the hair is obtained when the composition is applied to the hair. This soft wax hardens on the hair when the volatile ingredients evaporate. When the composition includes a propellant gas a wax with a larger surface area (wax snow) is produced, which is likewise easily worked into the hair and very effectively fixes or sets the hair.

Abstract: Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thickeners has a viscosity of at least 4,000 centipoise at 23 degrees C. and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.

Abstract: The present invention provides a method for preparing biodegradable porous polymer scaffolds for tissue engineering, comprising: a) fabricating a polymer sample from a polymer solution containing at least one biodegradable polymer and an effervescent mixture; b) effervescing the polymer sample in the presence of an effervescent medium such as an aqueous alcohol solution; and c) drying. The method for preparing biodegradable polymer scaffolds of the present invention has the advantages that the process is simple, that pore size can be easily controlled, that the problem caused by the secretion and existence of the toxic substance can be avoid by using a material harmless to human body, and that high efficiency can be achieved. In addition, biodegradable porous polymer scaffolds prepared by above method have the advantages that high porosity can be achieved and an open cell structure in which pores are interconnected is obtained.

Abstract: A pharmaceutical preparation for the treatment of wounds and ulcers in humans and animals and a method of preparation of the same are provided here. The composition consists of an alcoholic extract of Huangqin, Huanglian, Huangbai, Opuntia, Dilong, and &bgr;-sitosterol (from Soybean extract), in a vegetable oil-wax base, from where the alcohol is essentially removed by evaporation. The composition is used as a topical ointment for the treatment of wounds in its preferred embodiment. Wounds, in particular those occurring in the skin as second and third degree burns, stasis ulcers, trophic lesions, such as decubitus ulcers, diabetic ulcers, surgical wounds, severe cuts, diaper rash, cracked nipples and abrasions which are commonly resistant to the natural healing process, may be treated with this composition.

Abstract: 10-Hydroxy-2-decenoic acid compounds, particularly the 10-hydroxydec-2-enoates, are well suited for promoting desquamation of human skin and/or stimulating epidermal renewal and thus combating intrinsic and/or extrinsic cutaneous aging.

Abstract: The proliferation of uterine fibroid leiomyoma cells is inhibited by certain Fibroid Cell Growth Inhibitor (FGI) agents. The pharmacological doses of these FGI agents in the milieu of uterine fibroid cells can be made high enough to not only inhibit proliferation, but to also causes cell death. Non-invasive or minimally invasive, non-systemic delivery methods are used to deliver the FGI agent to the milieu of the target fibroid leiomyoma cell population, thereby avoiding the disadvantages and side effects of surgical and systemic hormonal therapy interventions in the treatment of uterine fibroids. The FGI agents are substrates that are normally present or are well tolerated in the human body. The efficacy of the FGI agents appears to be related to their ability to moderate the Protein Kinase C and Mitogen Activated Protein Kinase pathways. Specific FGI agents shown to be useful to inhibit growth or proliferation of uterine fibroid cells include: &agr;-tocopherol, &agr;-tocopherol succinate, and troglitazone.

Abstract: The present patent describes a three-dimensional inter-connected open cell porous foams that have a gradient in composition and/or microstructure through one or more directions. These foams can be made from a blend of absorbable and biocompatible polymers that are formed into foams having a compositional gradient transitioning from predominately one polymeric material to predominately a second polymeric material. These gradient foams are particularly well suited to tissue engineering applications and can be designed to mimic tissue transition or interface zones.

Abstract: A range of products and methods are based on a creamy base of cream, artificial cream, thickened cream, cream cheese, mixtures thereof and mixtures with compatible incidental ingredients, the creamy base being aerated while cold and intimately mixed with a hot aqueous gelatin solution typically around 80° C. and providing 1-3% gelatin in the mixed product and the overrun in the aeration being typically in the range of 10-40%. Various further components are included or introduced with further processing selected from methods including heating the product with a further component to boiling point whereby de-aeration and enhanced shelf life is found in the resultant product. An alternative method is where flavor components are added prior to de-aeration. Another application is as a carrier for a pharmaceutical agent which is incorporated into the creamy base and protected with the gelatin matrix, a powder being formed ready for packaging in pharmaceutical doses.

Abstract: Hair treatment compositions in the form of pump sprays and pump foams that are free from propellant gases comprise at least one cationic and at least one anionic polymer having methacrylic and ethyl units.

Abstract: The use of one or more cosurfactants (surfactant B) in a mixture with one or more surfactants different from surfactant B (surfactant A) for reducing the binding of surfactant A to the surface of the skin.

Abstract: A deodorant composition with active antibacterial constituents comprising on a weight basis the plant extracts of Myrtus from about 2% to about 8%, Laurus nobilis, from about 1% to 5% Drosera extract from about 1% to 7%, Myrrhis resin from about 3% to about 6%, and water 74% to 93%. Preferably, the composition is free of alcohol and aluminum.

Abstract: The present invention relates to a method for obtaining improved photostability of a sunscreen composition that contains at least two sunscreen active ingredients, which are photo-unstable when formulated together, by microencapsulating at least one of said active ingredients in an encapsulating material suitable for holding the encapsulated active ingredient material, thus reducing or preventing its leaching out of the capsules; and adding other acceptable components and additives needed for the preparation of said composition. The sunscreen active ingredients can be selected from UVA and UVB absorbers, preferably a combination thereof. In a preferred embodiment of the present invention said active ingredients are encapsulated in separate sol-gel microcapsules.

Abstract: Formulations have been developed for regional delivery of drugs, for example, into a cavity such as the pelvic region, peritoneal region, or directly on organs of interest. Regional delivery increases comfort and bioavailability of the drug, resulting in rapid and relatively high blood levels in the regions to be treated in the substantial absence of side effects due to the high levels required for efficacy following systemic delivery. In the preferred embodiment, these formulations consist of drug micro or nanoparticles, which may be formed of drug alone or in combination with an excipient or polymeric carrier. The excipient or polymer may be used to manipulate release rates and to increase adhesion to the affected region. The drug formulation can be applied as a dried powder, a liquid suspension or dispersion, or as a topical ointment, creme, lotion, foam or suppository.

Abstract: The invention relates to non-emulsion, topical gel compositions which comprise an aliphatic polyhydric alcohol, an alkali salt of a fatty acid ester, a carbohydrate-based or cholesterol-based surfactant/emulsifier, or combination thereof, water, and substantially no oil.

Abstract: A cleansing composition comprising:

Abstract: The present invention teaches liquid sunscreen compositions in which level of surfactant is higher than level at which the sunscreen component(s) are still soluble in the surfactant in which they are used; and which comprise minimal levels of cationic polymer. Combination of cationic polymer (especially preferred surfactants and at minimum levels) and minimal levels of sunscreen lead to compositions with minimal levels of deposition and minimal SPF. Further, the compositions also maintain good lather.

Abstract: An aqueous non-aerosol hair styling composition having 55% or less VOC content, said composition comprising (i) a water soluble or dispersable fixative polymer of about 10 to about 1000 Kilo Daltons and in an amount ranging from 1% to 40% by weight of the composition; (ii) a neutralizing agent in an amount ranging from 0.1 to 10% by weight and selected from the group consisting of 2-amino, 2-methyl, 1-propanol, dimethyl stearamine, sodium hydroxide, and potassium hydroxide; (iii) a surfactant in an amount ranging from 0.01% to 5% by weight and selected from the group consisting of sodium dioctyl sulfo succinate, sodium dodecyl sulfate, cocoamidopropyl betaine, and sodium laureth sulfate; (iv) a salt ranging from 0.01% to 10% by weight and selected from the group consisting of sodium benzoate, and magnesium acetate; (v) an alcohol ranging from 10% to 90% by weight; and (vi) water ranging from 10% to 90% by weight.

Abstract: A hair cosmetic composition having an excellent hair setting property, and which imparts to hair good flexibility and a good finish feeling. The hair cosmetic composition comprises (a) a water-soluble amine-oxide-containing polymer having a weight-average molecular weight of 10,000 to 500,000 and (b) a water-soluble polymer selected from the group consisting of nonionic, cationic, anionic and amphoteric polymers. The weight ratio of component (a) to component (b) falls within a range of from 1:10 to 10:1. Components (a) and (b) are incorporated in a total amount of from 0.1 to 10 wt. % based on the hair cosmetic composition.

Abstract: A method for improving the corrosion resistance of aerosol or foam hair spray formulations in metal containers is disclosed. In particular, the present invention involves the use of phosphate ester emulsifiers in the preparation of the emulsion polymer hair fixative resins to provide corrosion resistance of the hair styling composition in metal containers without negatively affecting the performance of the hair styling product itself. Use of the selected emulsifiers is particularly useful in non-corrosive aqueous hair styling compositions containing low (80% or less) volatile organic compound (VOC) concentrations.

Abstract: A water/oil/water triple emulsion comprising an aqueous external phase and a W/O primary emulsion comprising an oily phase and an aqueous internal phase, which comprises at least one partially or completely crosslinked organopolysiloxane elastomer comprising a polyoxyethylenated and/or polyoxypropylenated chain. The emulsion may be used, for example for cleansing and/or treating and/or protecting the skin and/or mucous membranes and/or keratinous fibers.

Abstract: Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thickeners has a viscosity of at least 4,000 centipoise at 23 degrees C. and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.

Abstract: An effective and gentle formulation for the treatment and prevention of pseudofolliculitis barbae and skin irritation and method for the application of same is provided herein. In its preferred embodiment, the formulation consisting essentially of a petroleum balance containing 10% to 20% camphor, 5% fragrance oil and 1% to 2% mineral oil. The formulation is designed to prevent the razor bumps associated with pseudofolliculitis barbae without the use of harsh chemical compounds while allowing the user to continue to use a traditional method of shaving. The formulation is applied through a method consisting of shaving normally with a razor, application of a thin veneer of the formulation to the shaved area and removal of the formulation by means of a wet washcloth or other means.

Abstract: A composition for use as a post-foaming shaving gel, for example, comprising about 3% to about 20% by weight of the composition of a surfactant system, about 0.05% to about 10% by weight of the composition of poly(ethylene oxide) and polyvinylpyrrolidone, in a combined amount, wherein the poly(ethylene oxide) and the polyvinylpyrrolidone are present in a weight ratio of about 1:10 to about 10:1, and about 0.1% to about 10% by weight of the composition of a post-foaming agent.

Abstract: An oil/water/oil triple emulsion is stabilized with at least one partially or completely crosslinked organopolysiloxane elastomer having at least one polyoxyethylenated and/or polyoxypropylenated chain. The stable triple emulsion can be used as a composition for topical application, in particular as a cosmetic or dermatological composition, and especially as a vehicle for active principles. The emulsion is particularly useful for cleansing and/or treating and/or protecting the skin and/or mucous membranes and/or keratinous fibers.