Solid Candy Type Patents (Class 514/948)
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Patent number: 4882155Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882159Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkylenglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882151Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lenghts of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant maerial selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882158Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882152Abstract: A chewable delivery system for actives comprising:(a) an active pre-coatd with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and p1 (b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882160Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 13, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882154Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons of less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 13, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882157Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882156Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4882153Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 13, 1988Date of Patent: November 21, 1989Assignee: Warner Lambert Co.Inventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4879108Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: October 14, 1988Date of Patent: November 7, 1989Assignee: Warner-Lambert CompanyInventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4851392Abstract: The present invention relates to an ingestible aggregate comprising a pre-swelled substantially anhydrous hydrocolloid and a substrate. More particularly this invention relates to an aggregate having as a substrate a dietary fiber and/or drug wherein the composition can be administered in a therapeutically effective amount. Hydrocolloids useful include natural and modified gums, celluloses, modified celluloses, pectins, mucillages, modified starches, noncellulose polysaccharides, algal polysaccharides and mixtures thereof. The aggregate should be in the size range of about 4 to about 70 U.S. mesh. The unpleasant taste and mouthfeel of the fiber and/or drug is effectively masked and substantial hydration is delayed until the composition reaches the stomach. The compositions are substantially more platable, devoid of graininess, bitterness or fibrous texture. The pleasant taste of the composition encourages patient compliance with their fiber or drug therapy.Type: GrantFiled: February 29, 1988Date of Patent: July 25, 1989Assignee: Warner-Lambert CompanyInventors: James J. Shaw, Shri C. Sharma
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Patent number: 4832994Abstract: Anti-smoking oral preparations are provided containing a silver compound as the anti-smoking agent and a sweetener in which the silver compound is present in amounts of from 0.1 mg. to 2.5 mg. and the ratio of sweetness intensity based on sucrose to silver compound content is from 100:1 to 2500:1.Type: GrantFiled: September 2, 1987Date of Patent: May 23, 1989Inventor: Michael S. Fey
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Patent number: 4829056Abstract: Pharmaceutical compositions in the form of a buccal tablet comprising etorphine or a salt thereof, at least one monosaccharide, disaccharide or a mixture thereof, and a mixture of xanthan gum and locust bean gum in a weight ratio 3:1 to 1:1, wherein the total weight of the mono- and/or di-saccharides relative to the combined weight of the xanthan and locust bean gums is in the ratio of 20:1 to 3:1. The tablet affords improved bioavailability.Type: GrantFiled: April 10, 1987Date of Patent: May 9, 1989Assignee: Reckitt & Colman Products LimitedInventor: Keith Sugden
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Patent number: 4808410Abstract: Novel pharmaceutical compositions of matter are disclosed for use in eliciting a topical anesthetic and antimicrobial response, preferably for oral health care purposes, said compositions comprising dyclonine hydrochloride and phenol. When used in combination, dyclonine hydrochloride and phenol provide an improved antimicrobial response.Type: GrantFiled: December 16, 1987Date of Patent: February 28, 1989Assignee: Richardson-Vicks Inc.Inventors: James V. Sorrentino, William J. Kelleher, Jeanne O. Moye
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Patent number: 4806356Abstract: There is disclosed a nicotine containing lozenge prepared from a mixture of inert filler material, a binder and either pure nicotine or a nicotine containing substance by a technique not involving any application of heat. Cold compression in a conventional tablet making machine is preferred.Type: GrantFiled: April 3, 1987Date of Patent: February 21, 1989Inventor: Alec S. W. Shaw
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Patent number: 4781920Abstract: The invention provides physically stable anthelmintic paste compositions containing resinates of d1-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole and other anthelmintic compounds in combination with a wide variety of therapeutic agents such as antibiotics, vitamins, vaccines, or mineral supplements.Type: GrantFiled: September 3, 1985Date of Patent: November 1, 1988Assignee: American Cyanamid CompanyInventor: James M. Quinlan
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Patent number: 4778676Abstract: A chewable delivery system for actives comprising:(a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lengths of about 4 carbons or less, glycerides having a melting point of 100.degree. C. or less, polyalkyleneglycols having a molecular weight of 3,700 or less, synthetic and natural waxes and mixtures thereof; and(b) a confectionery matrix comprising a binder system comprising gelatin and a humectant material selected from the group consisting of glycerin and its lower alkyl (C.sub.2-7) ester derivatives; a sweetener; and about 1% to about 30% by weight water.Type: GrantFiled: December 20, 1985Date of Patent: October 18, 1988Assignee: Warner-Lambert CompanyInventors: Robert K. Yang, Shri C. Sharma, Shan-Shan Sheu, James J. Shaw
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Patent number: 4762719Abstract: A cough drop is provided comprising a hard candy outer shell and a powdered centerfill containing a rapidly-dissolving powder such as dextrose monohydrate and an active ingredient such as menthol and eucalyptus which is preferably in the form of a liquid blend and a spray-dried powder. The hard candy outer shell also contains menthol and eucalyptus as a liquid blend.When the outer shell is dissolved in the mouth or the centerfill is bitten into, the rapidly-dissolving powder acts to enhance the active-ingredient's activity in the mouth so that a discernible vaporization of active-ingredient is felt.Type: GrantFiled: August 7, 1986Date of Patent: August 9, 1988Inventor: Mark Forester
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Patent number: 4761274Abstract: A medicament adsorbate of analgesics and process for making same. The medicament adsorbate comprises a complex magnesium aluminum silicate having sorbed therein an analgesic. The complex magnesium aluminum silicate has the following typical chemical analysis:______________________________________ Ratio to Percent by Weight Aluminum Oxide ______________________________________ Silicon dioxide 56 to 59 14.0 to 29.5 Magnesium oxide 21 to 24 5.2 to 12.0 Aluminum oxide 2.0 to 4.0 1 Ferric oxide 0.4 to 0.6 Calcium oxide 1.1 to 1.5 Sodium oxide 2.5 to 3.5 Potassium oxide 0.5 to 1.0 Ignition Loss 5.5 to 12.Type: GrantFiled: October 16, 1987Date of Patent: August 2, 1988Assignee: Warner-Lambert CompanyInventors: John Denick, Jr., David Peters, Anil K. Talwar, Wei C. Liao
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Patent number: 4761407Abstract: New solid galenical form for oral administration, consisting of a mixture of one or more active products and two or more excipients which can be liquefied at a temperature compatible with the active product or products, and which are solid at ambient temperature.Type: GrantFiled: October 22, 1985Date of Patent: August 2, 1988Assignee: Rhone-Poulenc SanteInventors: Jean-Jacques Campan, Roberto Lombardi
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Patent number: 4758424Abstract: A medicament adsorbate of decongestants and process for making same. The medicament adsorbate comprises a complex magnesium aluminum silicate having sorbed therein a decongestant. The complex magnesium aluminum silicate has the following typical chemical analysis:______________________________________ Ratio to Percent by Weight Aluminum Oxide ______________________________________ Silicon dioxide 56 to 59 14.0 to 29.5 Magnesium oxide 21 to 24 5.2 to 12.0 Aluminum oxide 2.0 to 4.0 1 Ferric oxide 0.4 to 0.6 Calcium oxide 1.1 to 1.5 Sodium oxide 2.5 to 3.5 Potassium oxide 0.5 to 1.0 Ignition Loss 5.5 to 12.Type: GrantFiled: October 16, 1987Date of Patent: July 19, 1988Assignee: Warner-Lambert CompanyInventors: John Denick, Jr., David Peters, Anil K. Talwar, Wei C. Liao
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Patent number: 4758425Abstract: A medicament adsorbate of antiasthmatics and process for making same. The medicament adsorbate comprises a complex magnesium aluminum silicate having sorbed therein an antiasthmatic. The complex magnesium aluminum silicate has the following typical chemical analysis:______________________________________ Ratio to Percent by Weight Aluminum Oxide ______________________________________ Silicon dioxide 56 to 59 14.0 to 29.5 Magnesium oxide 21 to 24 5.2 to 12.0 Aluminum oxide 2.0 to 4.0 1 Ferric oxide 0.4 to 0.6 Calcium oxide 1.1 to 1.5 Sodium oxide 2.5 to 3.5 Potassium oxide 0.5 to 1.0 Ignition Loss 5.5 to 12.Type: GrantFiled: October 16, 1987Date of Patent: July 19, 1988Assignee: Warner-Lambert CompanyInventors: John Denick, Jr., David Peters, Anil K. Talwar, Wei C. Liao
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Patent number: 4716033Abstract: A medicament adsorbate and process for making same. The medicament adsorbate comprises a complex magnesium aluminum, silicate having sorbed therein a medicament drug and a surfactant.Type: GrantFiled: March 27, 1986Date of Patent: December 29, 1987Assignee: Warner-Lambert CompanyInventor: John Denick, Jr.
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Patent number: 4671953Abstract: The present invention is directed to methods and compositions for noninvasively administering drugs having a sedative, analgesic, or anesthetic effect. A drug capable of absorption through mucosal tissues in incorporated into a candy matrix, which is then advantageously formed into a lollipop. A patient is put at ease when given the lollipop, and the drug rapidly enters the patient's bloodstream as the lollipop is sucked. When sedating or anesthetizing the patient, the physician can observe the patient's condition and remove the lollipop when it has had a desired effect on the patient. Alternatively, the physican can alter placement of the lollipop to slow the rate of the drug release for absorption into the patient's system. An analgesic-containing lollipop can be self-administrated by a patient in response to his own subjective experience of pain and to the patient's susceptibility to the particular drug utilized.Type: GrantFiled: May 1, 1985Date of Patent: June 9, 1987Assignee: University of Utah Research FoundationInventors: Theodore H. Stanley, Brian Haque
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Patent number: 4659571Abstract: A compressed powder formulation which consists essentially of an organophilic clay and at least one topical agent. The formulation maintains its physical integrity upon handling thereby permitting the preparation of the formulation in the form of self-supporting sticks and exhibits an acceptable level of payout. Additionally, the formulation retains an acceptable level of payout even when contacted with water. A process of making the formulation by compressing a powderous mixture is also set forth.Type: GrantFiled: March 20, 1985Date of Patent: April 21, 1987Assignee: NL Industries, Inc.Inventor: Dennis Laba
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Patent number: 4647448Abstract: The invention describes a pharmaceutical dosage unit suitable for oral administration with at least one face having a recess, which recess extends from one edge across and into the face; the recess being so shaped as to accommodate at least the tip of the user's tongue.Type: GrantFiled: December 21, 1984Date of Patent: March 3, 1987Assignee: Smith Kline & French Laboratories LimitedInventor: Geoffrey D. Tovey
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Patent number: 4642231Abstract: A medicament adsorbate containing a magnesium trisilicate having a surface area of at least 400 m.sup.2 /g and having a flake-like structure with multiple interstitial spaces, and having adsorbed therein from about 1% to about 20% by weight of the adsorbate of a medicament drug, wherein the medicament drug is an antihistamine.Type: GrantFiled: December 19, 1985Date of Patent: February 10, 1987Assignee: Warner-Lambert CompanyInventors: David Peters, John Denick, Jr., Anil K. Talwar
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Patent number: 4610871Abstract: Dentifrice formulations containing monoalkyl and dialkyl ethers of dianhydrohexitols in the form of toothpaste, mouthwash, chewing gums, confections, toothpicks and dental floss are effective in the treatment of oral surfaces and cavities to reduce irritation and plaque accumulation caused by the action of bacteria.Type: GrantFiled: December 27, 1985Date of Patent: September 9, 1986Assignee: ICI Americas Inc.Inventor: Matthew J. Lynch