Two Or More Diverse Proteins Or Polypeptides Patents (Class 524/20)
  • Publication number: 20140085998
    Abstract: The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate.
    Type: Application
    Filed: August 23, 2013
    Publication date: March 27, 2014
    Applicant: Danisco US Inc.
    Inventors: Richard R. Bott, Rasmus B. Jensen, Bradley R. Kelemen, Donald E. Ward II, Gregory M. Whited
  • Patent number: 8546482
    Abstract: This invention provides stable aqueous compositions including stable coating compositions, and methods of their production. The stable aqueous compositions and stable aqueous coating compositions comprise one or more emulsion-polymerized addition polymer, one or more carboxylesterase enzyme, and one or more carboxylesterase deactivating agent, such that the ester hydrolysis activity in the composition is less than 0.010 micromole/minute, and wherein the aqueous composition has a headspace volatile organic compound (VOC) content, as measured by headspace gas chromatography-mass spectrometry (GC-MS) at 33° C., of less than 10 ppm of organic carboxylester with a normal boiling point of less than 150° C. and more than 50 ppm of mono-alcohol with a formula molecular weight of less than 76.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: October 1, 2013
    Assignee: Rohm and Haas Company
    Inventors: James Bohling, Paul F. Doll, David L. Frattarelli, Kathleen R. Manna, Alvin M. Maurice
  • Publication number: 20110166257
    Abstract: This invention provides stable aqueous compositions including stable coating compositions, and methods of their production. The stable aqueous compositions and stable aqueous coating compositions comprise i) an aqueous dispersion of one or more emulsion-polymerized addition polymer comprising polymerized units of one or more carboxylester monomer, wherein at least one carboxylester monomer is a vinyl ester monomer; ii) one or more carboxylesterase enzyme; iii) one or more mono-alcohol with a formula molecular weight of less than 76; iv) optionally, acetaldehyde; and v) optionally, one or more organic carboxylester with a normal boiling point of less than 150° C.; and wherein the aqueous composition has a headspace volatile organic compound (VOC) content, as measured by headspace gas chromatography-mass spectrometry (GC-MS) at 33° C.
    Type: Application
    Filed: December 10, 2010
    Publication date: July 7, 2011
    Inventors: James Bohling, Paul F. Doll, David E. Frattarelli, Kathleen R. Manna, Alvin M. Maurice
  • Publication number: 20110152406
    Abstract: This invention provides stable aqueous compositions including stable coating compositions, and methods of their production. The stable aqueous compositions and stable aqueous coating compositions comprise one or more emulsion-polymerized addition polymer, one or more carboxylesterase enzyme, and one or more carboxylesterase deactivating agent, such that the ester hydrolysis activity in the composition is less than 0.010 micromole/minute, and wherein the aqueous composition has a headspace volatile organic compound (VOC) content, as measured by headspace gas chromatography-mass spectrometry (GC-MS) at 33° C., of less than 10 ppm of organic carboxylester with a normal boiling point of less than 150° C. and more than 50 ppm of mono-alcohol with a formula molecular weight of less than 76.
    Type: Application
    Filed: December 10, 2010
    Publication date: June 23, 2011
    Inventors: James Bohling, Paul F. Doll, David L. Frattarelli, Kathleen R. Manna, Alvin M. Maurice
  • Patent number: 7829611
    Abstract: A curable binder composition comprising an emulsion polymer, an extender and a hydryoxyamide.
    Type: Grant
    Filed: June 19, 2007
    Date of Patent: November 9, 2010
    Assignee: Rohm and Haas Company
    Inventor: Michael D. Kelly
  • Patent number: 7649036
    Abstract: Blended compositions and methods for the production of thermoset compositions of soy meal, which has been treated to remove non-thermoplastic materials associated with soy beans, and natural rubber. Also provided is a method for the preparation of a prepared granular soy meal by blowing a gas through a stream of granular natural soy meal to remove hulls and cellulose fiber materials which are lighter than the granular soy meal to provide the prepared granular soy meal for the compositions. The compositions are elastic and can be used in place of rubber bands and the like.
    Type: Grant
    Filed: August 10, 2005
    Date of Patent: January 19, 2010
    Assignee: Board of Trustees of Michigan State University
    Inventors: Amar K. Mohanty, Qiangxian Wu, Susan Selke
  • Patent number: 7285580
    Abstract: The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the strength of the interface between the tissue and the adhesive matrix. The primer molecules described herein function to interact with a protein present in the tissue, thereby altering its characteristics to make it more amenable to bonding with the adhesive matrix. Primer molecules may be applied to the tissue independently from the tissue adhesive or sealant or may be mixed with the tissue adhesive or sealant prior to application to the tissue.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: October 23, 2007
    Assignee: Protein Polymer Technologies, Inc.
    Inventor: Erwin R. Stedronsky
  • Patent number: 6987138
    Abstract: This invention provides a novel rapidly biodegradable polylactide resin composition while maintaining the good mechanical strength and physical properties of polylactide. This biodegradable polylactide resin composition comprises at least one protein selected from silk, gelatin, keratin, elastin, gluten, zein, or soybean. This composition further comprises degraded mannan, and furthermore, a filler.
    Type: Grant
    Filed: June 16, 2003
    Date of Patent: January 17, 2006
    Assignee: National Institute of Advanced Industrial Science & Technology
    Inventors: Yutaka Tokiwa, Takao Raku
  • Patent number: 6984609
    Abstract: A water-soluble granular composition including at least 40% of at least one plant growth regulator, at least one binder, at least one disaccharide and at least one surfactant; as well as methods for making and using the composition are disclosed. The water-soluble granular composition advantageously improves preparation of a solid plant growth regulator formulation for spray application, as such composition swiftly dissolves, is easily metered for application, can be more highly concentrated and is dust-free. A presently preferred water-soluble granular composition includes at least 40% of at least one gibberellin as the plant growth regulator.
    Type: Grant
    Filed: April 11, 2002
    Date of Patent: January 10, 2006
    Assignee: Valent BioSciences Corporation
    Inventors: Bala N. Devisetty, Robert M. Beach, Ricardo A. Menendez, Prem Warrior
  • Patent number: 6875796
    Abstract: The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the strength of the interface between the tissue and the adhesive matrix. The primer molecules described herein function to interact with a protein present in the tissue, thereby altering its characteristics to make it more amenable to bonding with the adhesive matrix. Primer molecules may be applied to the tissue independently from the tissue adhesive or sealant or may be mixed with the tissue adhesive or sealant prior to application to the tissue.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: April 5, 2005
    Assignee: Protein Polymer Technologies, Inc.
    Inventor: Erwin R. Stedronsky
  • Patent number: 6576685
    Abstract: The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the strength of the interface between the tissue and the adhesive matrix. The primer molecules described herein function to interact with a protein present in the tissue, thereby altering its characteristics to make it more amenable to bonding with the adhesive matrix. Primer molecules may be applied to the tissue independently from the tissue adhesive or sealant or may be mixed with the tissue adhesive or sealant prior to application to the tissue.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: June 10, 2003
    Assignee: Protein Polymer Technologies, Inc.
    Inventor: Erwin R. Stedronsky
  • Patent number: 6545082
    Abstract: A coating material contains at least one substance selected from the group consisting of water-soluble resin such as water-soluble acryl resin, resin emulsion such as acryl emulsion and solvent resin such as solution of urethane resin into a solvent (A); resin beads such as polyethylene beads (B); and at least one substance selected from the group consisting of soluble protein such as collagen and resin emulsion incompatible with the (A) such as ethylene-acryl copolymer (C). (A) improves adhesion with a base member, (B) improves heat sealability and (C) improves surface lubricity and anti-blocking properties. Further, water-soluble amine additive (D) may be added to improve adhesion with olefin base member.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: April 8, 2003
    Assignee: Idemitsu Petrochemical Co., Ltd.
    Inventor: Takaharu Yasue
  • Patent number: 6335388
    Abstract: Prolamine-plant polar lipid compositions are provided, said compositions including a mixture of a prolamine, a plant polar lipid, at least one polyalcohol in a hydro-alcoholic solution, and an active agent, wherein the composition forms a substantially homogeneous dispersion with skin adhesive properties; wherein the dispersion forms a film and wherein the film contains a gradient of concentrations of the active agent.
    Type: Grant
    Filed: October 2, 1998
    Date of Patent: January 1, 2002
    Assignee: Lavipharm Laboratories Inc.
    Inventor: Spiros Fotinos
  • Patent number: 6291559
    Abstract: An improved vegetable protein adhesive binder which can be used in paper coating compositions at much lower levels than conventional vegetable protein adhesive binders while imparting to the paper coating composition rheological and other properties equivalent to conventional paper coating compositions containing higher levels of vegetable protein adhesive binders is prepared by forming an alkaline dispersion of a vegetable protein material and a polyacrylate, mixing the polyacrylate and the vegetable protein material at a temperature and for a time sufficient to achieve entanglement of the polyacrylate with the vegetable protein material, and co-precipitating the vegetable protein material and polyacrylate at the isoelectric point of the vegetable protein.
    Type: Grant
    Filed: May 19, 1999
    Date of Patent: September 18, 2001
    Assignee: Protein Technologies International
    Inventors: Thomas L. Krinski, K. C. Hou
  • Patent number: 6258872
    Abstract: The present invention concerns novel methods for enhancing the mechanical performance of tissue adhesives and sealants which comprises employing a primer molecule in association with a tissue adhesive or sealant, wherein the primer molecule serves to enhance the strength of the interface between the tissue and the adhesive matrix. The primer molecules described herein function to interact with a protein present in the tissue, thereby altering its characteristics to make it more amenable to bonding with the adhesive matrix. Primer molecules may be applied to the tissue independently from the tissue adhesive or sealant or may be mixed with the tissue adhesive or sealant prior to application to the tissue.
    Type: Grant
    Filed: June 22, 1998
    Date of Patent: July 10, 2001
    Assignee: Protein Polymer Technologies, Inc.
    Inventor: Erwin R. Stedronsky
  • Patent number: 6231879
    Abstract: This invention is directed to methods of manufacturing implantable biocompatible cell encapsulation devices, wherein the cell encapsulation devices have a jacket made of a permeable, biocompatible material that is loaded with a core made of a reticulate foam scaffold having interconnected pores, with cells that are dispersed in the interconnected pores.
    Type: Grant
    Filed: February 9, 1999
    Date of Patent: May 15, 2001
    Assignee: Neurotech S.A.
    Inventors: Rebecca Li, Tyrone F. Hazlett
  • Patent number: 5902844
    Abstract: Methods of forming solid pharmaceutical compositions comprise solubilizing water-soluble polymers and amino acid-based components having molecular weights ranging from about 100 daltons to about 200,000 daltons or pharmaceutically acceptable salts thereof in solvents; and separating the solvents from the water-soluble polymers and the amino acid-based components or pharmaceutically acceptable salts thereof to form solid pharmaceutical compositions comprising the water-soluble polymers and the amino acid-based components or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: May 11, 1999
    Assignee: Applied Analytical Industries, Inc.
    Inventor: Edward S. Wilson
  • Patent number: 5837755
    Abstract: A urea-resin composition comprising a urea-formaldehyde reaction product, cellulose material, and at least one substance selected from the group cosisting of .alpha.-amino acid, powdered collagen and gelatin. The present invention provides urea-resin compositions which, having a property to harden under heating, are themselves biodegradable and have sufficient physical properties to be applied for practical purposes.
    Type: Grant
    Filed: March 29, 1996
    Date of Patent: November 17, 1998
    Assignee: Showa Highpolymer Co., Ltd.
    Inventors: Eiichiro Takiyama, Yoshitaka Hatano
  • Patent number: 5733868
    Abstract: A composition and method for repairing damaged connective tissue is provided. The composition comprises pseudo-poly(amino acids) and/or classic poly(amino acids) that exhibit adhesiveness for connective tissues. The composition is formed into an adhesive tissue repair implant and pressed against the damaged tissue to adhere the adhesive composition to the tissue.
    Type: Grant
    Filed: April 16, 1996
    Date of Patent: March 31, 1998
    Assignee: DePuy Orthopaedics, Inc.
    Inventors: Dale R. Peterson, Samuel I. Stupp
  • Patent number: 5733538
    Abstract: A hemocompatible surface-modifying additive is provided for modifying polyurethane or polyurethane urea substrates. The additive has a polyurethane or polyurethane urea hard block or an alternative block which is miscible with the poly(urethane) or poly(urethane-urea) base polymer, a polysiloxane hydrophobic soft block, an optional hydrophilic spacer and a peptide selected from the group consisting of Arg-Gly-Asp, X-Arg-Gly-Asp, Arg-Gly-Asp-X and X-Arg-Gly-Asp-X', wherein X and X' are amino acids.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 31, 1998
    Assignee: Thoratec Laboratories, Inc.
    Inventor: Judy S. Riffle
  • Patent number: 5718954
    Abstract: Materials containing fine natural organic material particles are disclosed. As the fine particles, superfine silk fibroin particles are produced by a process comprising a first step of comminuting silk fibroin into coarse particles with dry mechanical comminuting means, a second step of comminuting the coarse silk fibroin particles into fine particles with dry mechanical comminuting means, and a third step of comminuting the fine silk fibroin particles into superfine particles with an average particle diameter of 10 .mu.m or below with dry mechanical comminuting means, the silk fibroin particles being beta-treated during or after at least one of the first to third comminuting steps. Specific examples of the material are films, sheets, paints, fiber treating materials, etc.
    Type: Grant
    Filed: July 17, 1995
    Date of Patent: February 17, 1998
    Assignee: Idemitsu Petrochemical Co., Ltd.
    Inventors: Masahiro Sano, Satoshi Mikami, Nobutaka Sasaki, Nobuo Kusamoto, Fumioki Fukatsu, Atsuhiko Ubara, Takaharu Yasue, Shigeru Ohyama
  • Patent number: 5587411
    Abstract: This invention presents a rubber composition wherein a determined amount of protein is mixed with unvulcanized rubber. Rubber products made of this rubber composition have sufficient strength for practical use and are harmless to human bodies. The rubber composition of the invention not requiring vulcanizing process is advantageous in eliminating the need of large-scale vulcanizing equipment. Combined use of a curing agent and protein will increase modulus higher than using the curing agent alone.
    Type: Grant
    Filed: November 30, 1993
    Date of Patent: December 24, 1996
    Assignee: Sumitomo Rubber Industries, Ltd.
    Inventors: Toshiaki Sakaki, Shinichi Nakade
  • Patent number: 5506285
    Abstract: To form a binder from naturally occurring products without extraction or purification steps, the binder utilizes proteins from the germ or endosperm of cereal grasses or from the seed of buckwheat, oil seed plants, Amaranthus or leguminous plants or from leaves. The protein has a thermoplastic microstructure with linear polymers of moleculer weight of at least 2,000 linked with peptide linkages of at least 50 in number. The naturally occurring product is ground or milled without further processing and thus includes carbohydrates, particularly as cellulose, and possibly fats, yeast or materials yielding ash upon burning, with the carbohydrates being at least 5 percent of the proteins by weight. The binder may include some initiators or catalysts to polymerize fats or other initiators or catalysts to polymerize proteins.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: April 9, 1996
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Delmar C. Timm, Ayodeji J. Ayorinde, Harold E. Egger
  • Patent number: 5385959
    Abstract: The present invention relates to a capsule for use in heavy duty liquid compositions which capsule comprises:(1) a component subject to degradative attack; and(2) a composite polymer which in turn comprises a hydrophilic portion and hydrophobic polymer core particle.
    Type: Grant
    Filed: March 25, 1993
    Date of Patent: January 31, 1995
    Assignee: Lever Brothers Company, Division of Conopco, Inc.
    Inventors: Liang S. Tsaur, Michael P. Aronson
  • Patent number: 5153242
    Abstract: To form a composition board from naturally occurring products without extraction or purification steps, the naturally occurring material is held together with a binder that is added or is already within the naturally occurring material. In one embodiment, the binder utilizes proteins from the germ or endosperm of cereal grasses or from the seed of buckwheat, oil seed plants, Amaranthus or leguminous plants or from leaves. The protein has a thermoplastic microstructure with linear polymers of molecular weight of at least 2,000 linked with peptide linkages of at least 50 in number. The naturally occurring product is ground or milled without further processing and thus includes carbohydrates, particularly as cellulose, and possibly fats, yeast or materials yielding ash upon burning, with the carbohydrates being at least 5 percent of the proteins by weight. The binder may include some initiators or catalysts to polymerize fats or other initiators or catalysts to polymerize proteins.
    Type: Grant
    Filed: February 21, 1991
    Date of Patent: October 6, 1992
    Assignee: The Board of Regents of the University of Nebraska
    Inventors: Delmar C. Timm, Ayodeji J. Ayorinde, Harold E. Egger
  • Patent number: 4963604
    Abstract: A polymeric or plastic pigment, useful as a partial replacement for the inorganic pigment conventionally employed in paper coating compositions is disclosed. The pigment comprises a copolymer of an animal or vegetable protein and a monomer havingh a glass transition temperature (Tg) greater than about 70.degree. C. polymerized in a surfactant free system. When employed in paper coating compositions the pigment provides a coating of improved gloss and ink holdout, as compared to a coating in which the pigment composition consists only of an inorganic material. Improved water resistance, improved water holding and a potential for reduction in the coating sticking to the calender during the paper finishing process are obtained as compared to conventional polymeric pigments.
    Type: Grant
    Filed: February 24, 1989
    Date of Patent: October 16, 1990
    Assignee: Protein Technologies International, Inc.
    Inventors: Charles E. Coco, Lawrence M. Scacciaferro
  • Patent number: 4675351
    Abstract: An adhesive formulation useful for applying a paper label to a glass bottle, having the tack and rheology making it suitable for use in modern labeling equipment, and imparting water immersion resistance in ice water for a period of at least 72 hours. Based on soy protein isolate; does not use casein.
    Type: Grant
    Filed: January 16, 1986
    Date of Patent: June 23, 1987
    Assignee: Borden, Inc.
    Inventor: Orville E. Brown
  • Patent number: 4632946
    Abstract: A halogen-free flameproofed thermoplastic molding material consists of a halogen-free thermoplastic resin (A) and one or more further halogen-free components.The thermoplastic resin (A) is present in an amount of from 30 to 90% by weight, based on the molding material. The latter contains, as further components, from 1 to 50% by weight of a phenol/aldehyde resin (B), from 1 to 50% by weight of a nitrogen-containing organic compound (C) and from 3 to 50% by weight of a phosphorus-containing organic compound (D), the percentages in each case being based on the molding material.The molding material is used for the production of flameproofed moldings.
    Type: Grant
    Filed: January 18, 1985
    Date of Patent: December 30, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Volker Muench, Juergen Hambrecht, Adolf Echte, Karl H. Illers, Johann Swoboda
  • Patent number: 4585797
    Abstract: A flexible continuous film is comprised of a physical admixture of a polypeptide, a plasticizer and a film-forming flexible polymer. When the film is moistened, the polypeptides exude therefrom.
    Type: Grant
    Filed: May 16, 1984
    Date of Patent: April 29, 1986
    Assignee: Seton Company
    Inventor: Gheorghe Cioca
  • Patent number: 4396733
    Abstract: The present invention relates to new azulmic acids stabilized by condensation with carbonyl compounds, several processes for their preparation and their use for various purposes.
    Type: Grant
    Filed: September 11, 1980
    Date of Patent: August 2, 1983
    Assignee: Bayer Aktiengesellschaft
    Inventors: Kuno Wagner, Kurt Findeisen
  • Patent number: 4351824
    Abstract: Methods of making and using a stable diagnostic reagent for use in serological testing procedures, and in particular, non-auto-agglutinating polystyrene latex particles with surfaces containing a protein, substantially methylated serum albumin, and a bound, negatively-charged polymeric compound. The particles may be sensitized with a number of negatively-charged compounds, including proteins, polysaccharides and various cell nuclear components. When the coated latex particles are adsorbed with native deoxyribonucleic acid, the resultant immunological reagent can be used to detect certain autoimmune diseases, particularly serum lupus erythematosus.
    Type: Grant
    Filed: February 5, 1981
    Date of Patent: September 28, 1982
    Assignee: ICL Scientific
    Inventor: Harris I. Lehrer