Abstract: Crosslinked biocompatible compositions comprising an ionically crosslinked component and a covalently crosslinked component for encapsulating biologics are disclosed. In accordance with the present invention, also disclosed are crosslinkable biocompatible mixtures comprising an ionically crosslinkable component and a covalently crosslinkable component. Methods for encapsulating biologics with the crosslinked and crosslinkable biocompatible compositions are provided. Also, retrievable macrocapsules for encapsulating microcapsules or biologics are disclosed.

Abstract: A molding based on finely divided organic and/or inorganic materials containing, as binder, the solid component of an aqueous polymer dispersion which is obtainable by polymerizing unsaturated monomers which can be polymerized by means of free radicals in the aqueous phase in the presence of a monosaccharide, oligosaccharide, polysaccharide, oxidatively, hydrolytically and/or enzymatically degraded polysaccharide, chemically modified monosaccharide, oligosaccharide or polysaccharide, or a mixture of the said compounds, by the process of free-radical aqueous emulsion polymerization.

Abstract: The invention relates to a process for the production of absorbers for water, aqueous solutions and body liquids, the absorbers consisting of at least two components A and B, whereby component A is at least a water-swellable synthetic polymer or copolymer, and component B is at least a natural or synthetic compound being present at normal temperature as a pourable powder which is highly or at least partially soluble, in water, or as a liquid. The present invention is characterized by the fact that component B is added in the form of a powder, a liquid or as a solution to component A during the end phase of the production process thereof after a polymer reaction degree of 90%, preferably 95% is attained, that is is mixed with the polymer gel of component A and, in order to obtain a powdery, pourable end product, is dried, if necessary, and ground.

Abstract: A binder for preparing an aqueous ceramics slurry, which contains a hydrophilic polymer such as a water-soluble (meth)acrylic polymer, a polysaccharide of natural origin such as pectin, pectinic acid, glucan, etc., and a polyvinyl compound such as poly(vinyl butyral). The aqueous ceramics slurry contains less than 25 parts by weight of the binder to 100 parts by weight of ceramics powder. The slurry is applied on a carrier film by a doctor blade method and dried to give a ceramics green sheet. A ceramics sheet can be produced by sintering the green sheet.

Abstract: A two phase adhesive matrix for use in an electrically powered iontophoretic delivery device is provided. The adhesive matrix comprises an adhesive hydrophobic polymer phase and about 15 to 60 wt % on a dry weight basis of a hydrophilic polymer phase distributed through the hydrophobic polymer phase. The hydrophilic phase forms upon hydration an interconnecting network of aqueous pathways for passage of the agent through the adhesive. The adhesive can be used to adhere an electrode assembly of an iontophoretic delivery device to a body surface such as skin or a mucosal membrane. Alternatively, the adhesive can be used to adhere together two or more elements of an iontophoretic delivery device.

Abstract: An adhesive composition suitable for use as an in-line contact adhesive for electrotransport drug delivery systems.

Abstract: Environmentally degradable blends comprising ethylene-carbon monoxide copolymers, polysaccharide, and optionally, unsaturated oil are disclosed. The invention polymer blends are both photodegradable and biodegradable.

Abstract: A lyophilized pharmaceutical composition comprised of a neocarzinostatin derivative having the formula (SMA)-(NCS)-(SMA), is made by a method including dissolving the neocarzinostatin derivative and stabilizing agent comprising at least one saccharide selected from the group consisting of monosaccharides, disaccharides and dextran in an aqueous buffer solution having a pH ranging from about 7.5 to about 9.5, the stabilizing agent being present in an amount by weight (titer) which is at least equal to that of the neocarzinostatin derivative, to provide a solution; adjusting the pH of the solution to provide a pH-adjusted solution having a pH of about 8.0.+-.0.5; sterilizing the pH-adjusted solution by filtration to provide a sterilized solution; and lyophilizing the sterilized solution.

Abstract: A method of stabilizing an aqueous dispersion of water-absorbent particles and at least one matrix-forming hydrophilic thickening agent comprises the steps of evacuating gas from said dispersion and subjecting the latter to compression by means of a relative pressure sufficient to irreversibly transform the dispersion into a stable particle-matrix system. A method of preparing a stable semi-solid preparation of dry, preferably bead-shaped water-absorbent particles comprises forming a homogenous dispersion comprising from 30 to 70% by weight of said beads, from 0.1% by weight of at least one hydrophilic thickening agent, capable of forming a matrix for said beads, and from 20 to 55% by weight of water, and stabilizing the dispersion formed as above. The water-absorbent particles may consist of cross-linked carbohydrates or polyacrylamide or derivatives thereof. The stable preparation may advantageously be packed in aerosol type containers and be used for the treatment of wounds and skin.

Abstract: Hydrocolloid adhesive compositions are disclosed comprising a rubbery elastomeric base having dispersed therein hydrocolloid particles, at least some of which are polycationic hydrocolloid particles. The compositions have enhanced resistance to breakdown by body fluids and are especially useful as wound dressings.

Abstract: A process for producing boron-containing ceramics such as boron carbide and boron nitride comprises pyrolyzing a blend of a precarbonaceous polymer such as polyacrylonitrile and a boron-containing polymer such as that formed by the reaction of a borane with a Lewis base. Pyrolyzation in an inert atmosphere yields boron carbide while pyrolyzation in a reactive gas burns away the precarbonaceous polymer and yields a ceramic comprising the reaction product of boron and the pyrolyzation gas. Boron nitride ceramics are formed by pyrolyzing the preceramic blend in ammonia.

Abstract: Swollen core/sheath polymeric particles are disclosed having one or more voids in the core formed by reaction with a base such as sodium hydroxide. The sheath contains styrene or similar monomer polymerized in an amount greater than 25 mole percent and the polymer is free of acid groups. The core contains acid groups. Swelling is effected at an elevated temperature and in the absence of an organic solvent.The swollen particles on drying in a paint or other composition have air in the voids and act then as opacifying agents.

Abstract: The present invention relates to a liquid suspension of a high molecular weight, water-soluble polymer or water-soluble salt prepared by admixing and water-soluble polymer with a hydrocarbon carrier fluid and a suspending agent comprising an aqueous emulsion of a copolymer comprising a water-insoluble and substantially hydrocarbon-insoluble polymer consisting of particles having a dry weight average particle size of below 10 .mu.m and which is formed from monomers of which 80% to 100% are hydrophobic, 30 to 100% are polar and 0% to 20% are hydrophilic. More particularly, the copolymer comprises from about 80% to about 100% C.sub.1-30 alkyl methacrylate monomers and from about 0% to about 20% hydrophilic monomers. Preferably, the copolymer comprises 90% to 100% 2-ethylhexylacrylate and from about 0.5% to about 10% acrylic acid. The liquid suspension is capable of supporting about 5 pounds of water-soluble polymer per gallon of suspension.

Abstract: A method of lyophilizing reagent-coated latex particles which results in a product easily reconstituted without agglutination, retains activity, and remains stable and active at storage at 4.degree. C.

Abstract: The process of preparing a formaldehyde-free, thermosetting resin which is especially useful for bonding lignocellulosic materials together to form plywood or particle board, which process comprises first reacting an aqueous preparation containing a carbohydrate raw material with a mineral acid to convert the carbohydrate to polymerizable reactants and second reacting the polymerizable reactants with ammonia to form the thermosetting resin. The resin can be further cross-linked to form an insoluble resinous material by heating.

Abstract: Medical grade pressure sensitive adhesive compositions comprising a homogeneous mixture of one or more polyisobutylenes or blends of one or more polyisobutylenes and butyl rubber, one or more styrene radial or block type copolymers, mineral oil, one or more water soluble hydrocolloid gums, and a tackifier. One or more water swellable cohesive strengthening agents, an antioxidant, and various other optional ingredients may be included within the adhesive composition.

Abstract: Compositions and methods are provided for forming a coated wood product having the appearance and texture of wood grain, which conceals joints on the wood surface and which is capable of accepting conventional wood stain.

Abstract: The present invention relates to new azulmic acids stabilized by condensation with carbonyl compounds, several processes for their preparation and their use for various purposes.

Abstract: Particles of active substance each comprising a core of a high molecular substance containing an aldehyde group and a coat applied to the aforementioned core and formed of the reaction product of the aforementioned aldehyde group-containing high molecular substance with a high molecular substance containing active hydrogen, which particles are manufactured by causing particles of the aforementioned aldehyde group-containing high molecular substance to assume a swelled state and allowing the swelled particles to be reacted upon by the aqueous solution of the aforementioned active hydrogen-containing high molecular substance.