Abstract: The invention provides a means of boosting the mechanical performance of shaped shaped medical devices comprising polymer hydrogels, such as stents, so that they may be more easily inserted into or removed from the body. In one aspect, the invention provides shaped medical devices having increased mechanical strength and comprising both ionic and covalent crosslinks. In another aspect, the invention provides a shaped medical device having a heterogeneous polymer composition and a variable dissolution or degradation rate along its length. The shaped medical devices according to the present invention retain their shape and stiffness during insertion into the body and can swell and soften inside the body to enhance patient comfort.
February 25, 2000
Date of Patent:
April 9, 2002
SciMed Life Systems, Inc.
Sheng Ping Zhong, Arthur R. Madenjian, Douglas E. Godshall, John M. Ronan, Samuel A. Thompson
Abstract: A patching compound for patching holes in drywall, cement, and the like, includes well known drywall mud material, water, and various other ingredients such as calcium carbonate, gypsum, perlite, mica, talc, clay, starch, cement, and a preservative, such as sorbic acid or a product sold as boroguard ZB. The various ingredients are mixed with water to provide a relatively soft and pliable filler compound. Silicone caulking may also be used for moisture retention, if desired. The compound is place in a dispenser for dispensing, and the dispenser may either be a relatively small dispenser for household use or a relatively large dispenser for commercial and industrial use. For the household use, the dispenser preferably includes a housing having an asymmetrical configuration in which is disposed a piston. The piston moves within the cylinder and is prevented from rotating by the asymmetrical configuration of the cylinder. Rotation of a threaded rod causes the piston to move the compound, as desired.