Mixed With Carboxylic Acid Or Derivative Reactant Or Polymer Therefrom Patents (Class 525/411)
  • Publication number: 20080233169
    Abstract: N-substituted 4-aza-caprolactone biodegradable polymers, including derivatives thereof, useful for making implantable medical devices and coatings therefore are provided. The medical devices and coatings of the present invention can also be used for in situ controlled release drug delivery and are useful for treating or preventing medical conditions such as restenosis, aneurisms and vulnerable plaque.
    Type: Application
    Filed: August 9, 2006
    Publication date: September 25, 2008
    Applicant: Medtronic Vasular, Inc.
    Inventors: Mingfei Chen, Peiwen Cheng, Kishore Udipi
  • Patent number: 7419703
    Abstract: The invention provides heat-curable thixotropic mixtures containing carbamate and/or allophanate groups, including at least one oligomer and/or polymer containing at least one of carbamate and allophanate groups, and at least one thixotropic agent that is a urea derivative preparable by reacting at least one amine and/or water with at least one isocyanate in the presence of at least one amino resin. The invention further provides processes for preparing the mixtures and coating materials, adhesives and sealing compounds prepared from the mixtures.
    Type: Grant
    Filed: August 26, 2005
    Date of Patent: September 2, 2008
    Assignee: BASF Coatings AG
    Inventors: Hubert Baumgart, Michael A Gessner, Bruce Oermann, Paul J Harris
  • Publication number: 20080194770
    Abstract: Biodegradable aliphatic/aromatic copolyester comprising 49 to 66 mol % of an aromatic polyfunctional acid; 51 to 34 mol % of an aliphatic acid, at least 70% of which is sebacic acid; and butandiol; and blends containing such copolyester.
    Type: Application
    Filed: March 17, 2006
    Publication date: August 14, 2008
    Applicant: Novamont S.p.A.
    Inventors: Catia Bastioli, Tiziana Milizia, Giovanni Floridi, Andrea Scaffidi Lallaro, Giandomenico Cella, Maurizio Tosin
  • Publication number: 20080125550
    Abstract: In a cured product having a thickness of 60 ?m obtained from an actinic energy ray-curable composition of the present invention, when a scratch mark is made at a vertical load of 235 mN using a diamond indenter with a tip diameter of 15 ?m, the scratch mark is repaired by a self-repairing ability under an atmosphere at 25° C. and at a relative humidity of 50%. Therefore, the actinic energy ray-curable composition is useful as coating agents or paints for products where scratch resistance is required.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 29, 2008
    Applicant: NATOCO CO., LTD.
    Inventors: Masahiro Hara, Tomihisa Ohno, Susumu Kawakami
  • Patent number: 7368511
    Abstract: This invention relates to a blend of biodegradable polymers comprising: (A) about 15% to about 60% by weight of at least one flexible biodegradable polymer (A) having a glass transition less than about 0° C., (B) about 85% to about 40% by weight of at least one rigid biodegradable polymer (B) having a glass transition greater than about 10° C.; said percentages being based on the total weight of the polymer blend; wherein said polymer blend has a unnotched Izod impact strength according to ASTM D256 of at least 9 ft-lbs/in at 23° C. In one embodiment, the polymer blend has a unnotched Izod impact strength according to ASTM D256 at least 20 ft-lbs/in at 23° C.
    Type: Grant
    Filed: December 6, 2004
    Date of Patent: May 6, 2008
    Assignee: Eastman Chemical Company
    Inventors: Wesley Raymond Hale, Candace Michele Tanner
  • Publication number: 20080102649
    Abstract: There is provided an underlayer coating forming composition for lithography that is used in lithography process of the manufacture of semiconductor devices and that has a high dry etching rate in comparison to photoresists, does not intermix with photoresists, and is capable of flattening the surface of a semi conductor substrate having holes of a high aspect ratio. The underlayer coating forming composition for lithography comprises, a compound having two or more protected carboxylic groups, a compound having two or more epoxy groups, and a solvent.
    Type: Application
    Filed: January 6, 2006
    Publication date: May 1, 2008
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Satoshi Takei, Tetsuya Shinjo, Keisuke Hashimoto, Yasushi Sakaida
  • Patent number: 7354531
    Abstract: A composition for use as a polymer electrolyte, wherein said composition includes one or more polar materials and one or more polyesters of formula III, wherein each unit A may be identical or different and is of the structure IV, wherein each unit B may be identical or different and is of the structure V, wherein R and R1 are each, independently, hydrogen, optionally substituted hydrocarbyl or an inert functional group; a process for preparing said composition; the use of said composition as a polymer electrolyte in coulometers, displays, smart windows, cells or batteries; and a cell and/or battery having said composition.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: April 8, 2008
    Assignee: Shell Oil Company
    Inventors: Wynham Henry Boon, Thomas Clayton Forschner, David Eric Gwyn, James R. MacCallum, Christopher John Smith, Michael John Smith
  • Patent number: 7335699
    Abstract: A description is given of water-soluble aminoplast ether copolymers of the following structural type: wherein Z is a glycoluril central unit, B is a radical of an essentially water-insoluble polymer and R1 is a radical of a hydrophilic organic compound. The ratio R1:B is selected within a range of about 1.5 to 4:1 and the overall mass of the water-soluble aminoplast ether copolymer is from about 2000 to 50 000 g/mol such that the copolymer is soluble in water and may be used as a dispersant for e.g. pigments in polar solvents, e.g. water.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: February 26, 2008
    Assignee: Sud-Chemie AG
    Inventors: Klaus Dziwok, Inge Krämer, Norbert Schall, Helmut Coutelle, Sabine Huth, Alan Steinmetz, Thadeus Schauer, Heinz Greisiger, Mark Entenmann
  • Patent number: 7288603
    Abstract: An object of the present invention is to obtain a novel polymeric material capable of forming a solid polymer electrolyte excellent not only in processability, solvent resistance and durability/stability but also in ion conductivity by introducing sulfonic acid group or phosphonic acid group into a polybenzazole compound having excellent properties in view of heat resistance, solvent resistance, mechanical characteristics and the like. Means attaining the object of the present invention is a polybenzazole compound including an aromatic dicarboxylic acid bond unit having sulfonic acid group and/or phosphonic acid group and satisfying either a condition that inherent viscosity measured in concentrated sulfuric acid is in the range of 0.25 to 10 dl/g or a condition that inherent viscosity measured in a methanesulfonic acid solution is in the range of 0.1 to 50 dl/g.
    Type: Grant
    Filed: November 12, 2001
    Date of Patent: October 30, 2007
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Yoshimitsu Sakaguchi, Kota Kitamura, Hiroaki Taguchi, Junko Nakao, Shiro Hamamoto, Hiroshi Tachimori, Satoshi Takase
  • Patent number: 7279534
    Abstract: The present invention provides block copolymers containing at least one block of a poly(heteroaromatic) polymer and at least two blocks of a non-conjugated polymer. The chemically different blocks of the copolymer are covalently bonded to each other in an alternating fashion through an appropriate linkage group. The poly(heteroaromatic) block may exist in its neutral or oxidized form, and when in the oxidized form, it associates with organic or inorganic counter-anions to balance the charge. The poly(heteroaromatic) polymer is an intrinsically conducting polymer (ICP), and when in the oxidized form it is electrically conducting. When the ICP block or blocks of the block copolymer are in the doped form, the block copolymer is electrically conducting. Preferably the conducting block copolymers have conductivities in the range 10?6-103 S/cm. Block copolymers of this invention are soluble or dispersible in water, one or more organic solvents, or in a mixture thereof at a level of at least about 0.1 g/liter.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: October 9, 2007
    Assignee: TDA Research, Inc.
    Inventors: Silvia DeVito Luebben, Brian Elliott, Carolina Wilson
  • Patent number: 7273910
    Abstract: Process for the preparation of a functionalized polymer containing an additive, in which process there is formed a compound that contains, besides at least one blocked isocyanate group, a free amino, hydroxy or carboxy group; this compound is linked to an additive via the free amino, hydroxy or carboxy group in the additive; this additive linked to the compound mentioned is contacted with a polymer that contains at least one free amino or hydroxyl group, at a temperature above the polymer's melting point and at least above 150° C., such that the blocked isocyanate group reacts with the free amino or hydroxy group of the polymer to form the functionalized polymer. The invention also relates to the intermediate products formed in the process and in the preparation thereof. Lastly, the invention relates to functionalized polymers and polymer compositions containing the functionalized polymer.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: September 25, 2007
    Assignee: DSM IP Assets B.V.
    Inventors: Jacobus Antonius Loontjens, Bartholomeus Johannes Margretha Plum, Albert Arnold Van Geenen, Weihua Ming
  • Patent number: 7268205
    Abstract: Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including interference screws), bone plates and bone plating systems, surgical mesh, repair patches, slings, cardiovascular patches, orthopedic pins (including bone filling augmentation material), adhesion barriers, stents, guided tissue repair/regeneration devices, articular cartilage repair devices, nerve guides, tendon repair devices, atrial septal defect repair devices, pericardial patches, bulking and filling agents, vein valves, bone marrow scaffolds, meniscus regeneration devices, ligament and tendon grafts, ocular cell implants, spinal fusion cages, skin substitutes, dural substitutes, bone graft substitutes, bone dowels, wound dressings, and hemostats.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: September 11, 2007
    Assignee: Metabolix, Inc.
    Inventors: Simon F. Williams, David P. Martin, Frank A. Skraly
  • Patent number: 7268182
    Abstract: A coating composition comprising a film forming binder of a. at least one polymer that has pendant groups, such as, hydroxyl, carboxyl, glycidyl, amine, amide, silane and mixtures thereof that are reactive with a crosslinking component and the polymer has a glass transition temperature (Tg) of 10 to 80° C.; b. a polytrimethylene ether diol having a Mn (number average molecular weight) of 500 to 5,000; and c. a crosslinking component, such as, organic polyisocyanates, melamine formaldehydes, alkylated melamine formaldehydes, benzoquanamine formaldehyde, urea formaldehyde, polyepoxides, silane resin and any mixtures thereof; wherein the coating composition can be used as a clear coating composition and can contain pigments and may be used as a pigmented top coating, a pigmented base coating, a primer or primer surfacer coating and is useful for coating automobile and truck bodies and parts, industrial equipment, appliances and exterior structures.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: September 11, 2007
    Assignee: E. I. du Pont de Nemours & Company
    Inventors: Hari Babu Sunkara, Patricia Mary Ellen Sormani, James William O'Neil, Joseph V. Kurian
  • Patent number: 7241832
    Abstract: Biodegradable polymer blends suitable for laminate coatings, wraps and other packaging materials are manufactured from at least one “hard” biopolymer and at least one “soft” biopolymer. “Hard” biopolymers tend to be more brittle and rigid and typically have a glass transition temperature greater than about 10° C. “Soft” biopolymers tend to be more flexible and pliable and typically have a glass transition temperature less than about 0° C. While hard and soft polymers each possess certain intrinsic benefits, certain blends of hard and soft polymers have been discovered which possess synergistic properties superior to those of either hard or soft polymers by themselves. Biodegradable polymers include polyesters, polyesteramides, polyesterurethanes, thermoplastic starch, and other natural polymers. The polymer blends may optionally include an inorganic filler. Films and sheets made from the polymer blends may be textured so as to increase the bulk hand feel.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: July 10, 2007
    Assignee: bio-tec Biologische Naturverpackungen GmbH & Co., KG
    Inventors: Kishan Khemani, Harald Schmidt, Simon K. Hodson
  • Patent number: 7214414
    Abstract: Biodegradable polymer blends suitable for laminate coatings, wraps and other packaging materials are manufactured from a blend of suitable biodegradable polymers, such as at least one “hard” biopolymer and at least one “soft” biopolymer. “Hard” biopolymers tend to be more brittle and rigid and typically have a glass transition temperature greater than about 10° C. “Soft” biopolymers tend to be more flexible and pliable and typically have a glass transition temperature less than about 0° C. While hard and soft polymers each possess certain intrinsic benefits, certain blends of hard and soft polymers have been discovered which possess synergistic properties superior to those of either hard or soft polymers by themselves. Biodegradable polymers include polyesters, polyesteramides, polyesterurethanes, thermoplastic starch, and other natural polymers. The polymer blends may optionally include an inorganic filler. Films and sheets made from the polymer blends may be textured so as to increase the bulk hand feel.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: May 8, 2007
    Assignee: biotec Biologische Naturverpackungen Gmb
    Inventors: Kishan Khemani, Harald Schmidt, Simon Hodson
  • Patent number: 7179883
    Abstract: Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices include sutures, suture fasteners, meniscus repair devices, rivets, tacks, staples, screws (including interference screws), bone plates and bone plating systems, surgical mesh, repair patches, slings, cardiovascular patches, orthopedic pins (including bone filling augmentation material), adhesion barriers, stents, guided tissue repair/regeneration devices, articular cartilage repair devices, nerve guides, tendon repair devices, atrial septal defect repair devices, pericardial patches, bulking and filling agents, vein valves, bone marrow scaffolds, meniscus regeneration devices, ligament and tendon grafts, ocular cell implants, spinal fusion cages, skin substitutes, dural substitutes, bone graft substitutes, bone dowels, wound dressings, and hemostats.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: February 20, 2007
    Assignee: Metabolix, Inc.
    Inventors: Simon F. Williams, David P. Martin, Frank A. Skraly
  • Patent number: 7175917
    Abstract: The present invention provides a biaxially oriented film of a polylactic acid resin that is suitable for films for bags and packaging films for various windows, particularly films for outlook window envelopes. The film is biodegradable and, as films for outlook window envelopes, is superior in the coating adaptability for an antistatic agent, a lubricant and an antiblocking agent or the like and in the high-speed cutting property. The present invention discloses a biaxially oriented film of a polylactic acid resin comprising not less than 50% by weight of a polylactic acid resin, which has a storage modulus E?at 80° C. within the range from 10 MPa to 3,000 MPa, as determined by the test method for temperature dependency of dynamic viscoelasticity, in accordance with JIS K7198 (method A); a heat shrinkage of not higher than 10%, upon heating at 80° C. for 10 seconds; and a tear strength in the width direction (TD direction) of the film of 10 to 200 mN, as determined in accordance with JIS K7128 (method B).
    Type: Grant
    Filed: October 29, 2002
    Date of Patent: February 13, 2007
    Assignee: Asahi Kasei Life & Living Corporation
    Inventors: Masayuki Sukigara, Mitsuyoshi Itada, Hisao Koike, Michihiro Yatsuzuka, Yoshiaki Hamada
  • Patent number: 7151142
    Abstract: The present invention is directed to a poly(ethylene glycol)-grafted aliphatic polyester represented by Formula 1: wherein X is an aliphatic ester, R is hydrogen or C1-5 alkyl, Z is the binding moiety of an initiator or a chain transfer agent, m/l is from 0.1 to 50, n is from 2 to 50, w is 1 or greater, and y is from 1 to 200. Further disclosed is a method for preparing the poly(ethylene glycol)-grafted aliphatic polyester of the present invention.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: December 19, 2006
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: Jung Ki Park, Seong-Nam Lee, Shi-Joon Sung, Ki-Yun Cho
  • Patent number: 7148315
    Abstract: Monomer addition methodology is provided to adjust monomer addition rates to a polymerization reactor. Advantages of the invention include control of bioabsorbable copolymer structure, improvement of monomer conversion, control of reaction temperature, and reduced reaction time. The overall result is an improved process and enhanced product performance. The technology is particularly useful in the copolymerization of monomers with different reactivity ratios, such as glycolide/lactide copolymers and glycolide/caprolactone copolymers. Monomer reactivity ratios and reaction kinetics are utilized to adjust monomer addition rates.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: December 12, 2006
    Assignee: Ethicon, Inc.
    Inventors: Modesto Erneta, Terry E. Lawler
  • Patent number: 7144976
    Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: December 5, 2006
    Assignee: Ethicon, Inc.
    Inventors: Takehisa Matsuda, Manabu Mizutani, Steven Arnold
  • Patent number: 7141643
    Abstract: A block copolymer is disclosed, which comprises a first block comprising polymerized units of an alkylene oxide and a second block comprising polymerized units of an alkylene oxide and a lactone, said copolymer being obtainable by polymerizing an alkylene oxide in the presence of an organic initiator to form said first block, and reacting the first block with a mixture of an alkylene oxide and a lactone. Such copolymers are found to have improved foam inhibition characteristics while maintaining their biodegradable properties.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: November 28, 2006
    Assignee: Cognis Performance Chemicals UK Ltd.
    Inventors: Elizabeth Dixon, John Robert Moxey
  • Patent number: 7138464
    Abstract: Absorbable heterochain polymers carrying acid or basic groups, capable of ionic conjugation with basic or acidic bioactive agents, respectively, are produced by free-radical addition of unsaturated functional monomers onto absorbable liquid polymers and subsequent generation of reactive functionality or by direct copolymerization of a carboxylic initiator with cyclic monomers to produce liquid carboxyl-bearing copolyesters or polyester carbonates.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: November 21, 2006
    Assignee: Poly Med, Inc
    Inventor: Shalaby W. Shalaby
  • Patent number: 7129319
    Abstract: An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible component is disclosed along with the use of such copolymer in medical devices which may contain a bioactive agent. The present invention also relates to a suture, stents, stent mantles and sealing devices made from the polyaxial copolymer.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: October 31, 2006
    Assignee: Poly Med Inc.
    Inventor: Shalaby W. Shalaby
  • Patent number: 7105629
    Abstract: The present invention includes photocurable, liquid polymers incorporating coumarin ester endgroups into their molecular structure, which polymers are crosslinked upon irradiation with ultraviolet light by photochemically allowed [2+2] cycloaddition reactions among the chain ends, and which crosslinked polymers are useful in the preparation of medical devices, tissue engineering scaffolds, drug delivery systems and, in particular, in vivo preparation of implants in an open surgical procedure or laproscopically.
    Type: Grant
    Filed: May 8, 2002
    Date of Patent: September 12, 2006
    Inventors: Takehisa Matsuda, Manabu Mizutani, Steven Arnold
  • Patent number: 7094864
    Abstract: The present invention uses a reactor that combines devices having a special portion structure to solve the difficulty of uniform blending due to the reactants becoming highly viscous, the difficulty of heat removal, and the increase in pressure loss, thus leading to continuous production of a polyester-based polymer stably having excellent quality.
    Type: Grant
    Filed: January 8, 2003
    Date of Patent: August 22, 2006
    Assignee: Daicel Chemical Industries, Ltd.
    Inventor: Jun Watanabe
  • Patent number: 7074883
    Abstract: Copolymers of lactide and glycolide with high glycolide content. The average glycolate block length is less then about 3, which allows the copolymer to be soluble in slightly polar solvents such as methylene chloride.
    Type: Grant
    Filed: December 1, 2003
    Date of Patent: July 11, 2006
    Assignee: Alkermes Controlled Therapeutics, Inc. II
    Inventor: Chiem V. Pham
  • Patent number: 7071288
    Abstract: The present invention is generally directed to a process for producing lactide-based polymers and the polymers produced by this process. The polymers of the present invention are terpolymers formed by the copolymerization of a lactide monomer, a linking monomer and an epoxy-terminated monomer. In one embodiment of the invention, the polymers may be formed from fluorine-containing monomers or aromatic ring-containing monomers. The disclosed materials may display improved hydrolytic and thermal characteristics as compared to previously known lactide-based materials. For example, the lactide based terpolymers may have a glass transition temperature over 60° C. For instance, lactide-based thermoplastic terpolymers of the present invention can have a glass transition temperatures of about 80° C. or higher. Lactide-based thermoset networks of the invention can have glass transition temperatures of up to about 200° C.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: July 4, 2006
    Assignee: Clemson University
    Inventors: Dennis W. Smith, Nilmini Abayasinghe
  • Patent number: 7070858
    Abstract: An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible component is disclosed along with the use of such copolymer in medical devices which may contain a bioactive agent. The present invention also relates to a suture, stents, stent mantles and sealing devices made from the polyaxial copolymer.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: July 4, 2006
    Assignee: Poly Med Inc
    Inventors: Shalaby W. Shalaby, Torbjorn Mathisen
  • Patent number: 7067596
    Abstract: The invention relates to a mixture of biodegradable polyesters which includes an aromatic-aliphatic polyester (A), an aliphatic polyester (B) and a polylactic acid polymer (C) in which the concentration of A varies, with respect to (A+B) in the range between 40 and 70% by weight, and the concentration of C with respect of (A+B+C) is of between 6 and 30% by weight.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: June 27, 2006
    Assignee: Novamont S.p.A
    Inventors: Catia Bastioli, Gianfranco Del Tredici, Italo Guanella, Tiziana Milizia, Roberto Ponti
  • Patent number: 7041417
    Abstract: This invention relates to an image receiving layer (22) of a receiver element (20) for laser-induced thermal transfer imaging processes. The image receiving layer (22) is made from a formulation containing a caprolactone polymer and a cellulose ester. The invention is, typically, useful in proofing and color filter applications.
    Type: Grant
    Filed: May 9, 2003
    Date of Patent: May 9, 2006
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Harvey Walter Taylor, Jr.
  • Patent number: 7026437
    Abstract: An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible component is disclosed along with the use of such copolymer in medical devices which may contain a bioactive agent. The present invention also relates to a suture, stents, stent mantles and sealing devices made from the polyaxial copolymer.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: April 11, 2006
    Assignee: Poly-Med, INC
    Inventors: Shalaby W. Shalaby, Dan Åkerfeldt, Fredrik Preiniz, Per Egnelöv, Torbjörn Mathisen
  • Patent number: 7019106
    Abstract: A process for producing a lactic acid polymer of 15,000 to 50,000 in weight-average molecular weight, the content of polymeric materials having not more than about 5,000 in weight-average molecular weight therein being not more than about 5% by weight, characterized by hydrolyzing a high molecular weight lactic acid polymer, placing the resultant solution comprising the hydrolyzed product under a condition capable of precipitating the objective lactic acid polymer, separating the precipitated lactic acid polymer and collecting them. The lactic acid polymer is useful as a matrix for sustained-release preparations. The sustained-release microcapsule preparation encapsulating a physiologically active substance can fully prevent the initial excessive release of the physiologically active substance from the microcapsules and keep a stable release rate over a long period of time.
    Type: Grant
    Filed: August 6, 2001
    Date of Patent: March 28, 2006
    Assignees: Wako Pure Chemical Industries, Ltd., Takeda Pharmaceutical Company Limited
    Inventors: Kohei Yamamoto, Tsutomu Tani, Takashi Aoki, Yoshio Hata
  • Patent number: 6911522
    Abstract: Compositions based on ?-caprolactone polymer, comprising at least one ?-caprolactone polymer and calcium carbonate. Process for preparing these compositions, which are used for manufacturing articles, in particular films, preferably obtained by extrusion blow-moulding or by flat-die extrusion.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: June 28, 2005
    Assignee: SOLVAY (Societe Anonyme)
    Inventors: Dino Manfredi, Ivan Claeys
  • Patent number: 6905987
    Abstract: Environmentally degradable melt spun fibers comprising a polyhydroxyalkanoate copolymer and a polylactic acid polymer or copolymer are disclosed. A preferred configuration of the present invention is directed to environmentally degradable fibers comprising a sheath/core structure where the core comprises a biodegradable polyhydroxyalkanoate copolymer and the sheath comprises a polymer or copolymer of polylactic acid. Nonwoven webs and disposable articles comprising the environmentally degradable fibers are also disclosed.
    Type: Grant
    Filed: January 17, 2002
    Date of Patent: June 14, 2005
    Assignee: The Procter & Gamble Company
    Inventors: Isao Noda, Eric Bryan Bond, David Harry Melik
  • Patent number: 6906148
    Abstract: The present invention relates to compositions comprising reaction products of a polyisocyanate with a polyester block copolymer and a process for the preparation thereof. These are suitable as a moisture-curing hot melt adhesive. The hot melt adhesive composition may optionally also comprise a reaction product of a polyisocyanate with a polyester polyol and/or a reaction product of a polyisocyanate with a polyether polyol. Such polyurethane hot melt adhesive compositions have good creep resistance and interfacial adhesion values on plastics and show very high strength values.
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: June 14, 2005
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Michael Krebs, Christoph Lohr, Andreas Brenger, Ingolf Scheffler
  • Patent number: 6903151
    Abstract: A wet-stick pressure-sensitive adhesive is provided wherein the pressure-sensitive adhesive comprises: at least one copolymerized monoethylenically unsaturated (meth)acrylic acid ester monomer, wherein the (meth)acrylic acid ester monomer, when homopolymerized, has a Tg of less than about 10° C.; at least one copolymerized hydrophilic acidic comonomer; and at least one nonreactive copolymer comprising at least two copolymerized alkylene oxides, at least one of which is hydrophobic and at least one of which is hydrophilic.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: June 7, 2005
    Assignee: 3M Innovative Properties Company
    Inventors: Donald H. Lucast, Dong-Wei Zhu
  • Patent number: 6861479
    Abstract: Production of a porous layer includes using a composition which includes a first polymer component and a second polymer component, the first polymer component being polyhydroxyamide and/or polybenzoxazole and stable at a temperature at which the second polymer component decomposes and volatilizes. If the composition is heated to the decomposition temperature of the second polymer component, the second component volatilizes and a porous layer that contains the first component remains.
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: March 1, 2005
    Assignee: Infineon Technologies AG
    Inventor: Recai Sezi
  • Patent number: 6831149
    Abstract: The present invention is directed to a process for making an absorbable polylactone copolymer prepared in part from about 2 to about 80 mole percent glycolide, which process utilizes a combination of a monofunctional polymerization initiator and a di-functional polymerization initiator, to achieve rates of crystallization of the copolymer of at least about 2 times faster than the rate of crystallization of a copolymer made by a similar process utilizing either the mono-functional or the di-functional polymerization initiator alone. Absorbable polylactone copolymers prepared by such processes and medical devices containing such copolymers are also disclosed.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: December 14, 2004
    Assignee: Ethicon, Inc.
    Inventors: Hugh D. Newman, Jr., Sasa Andjelic, Brian M. Kelly, Dennis D. Jamiolkowski, Rao S. Bezwada
  • Patent number: 6830747
    Abstract: Biocompatible biodegradable polymer or copolymer is capped at one end and has free hydroxyl at the other end. The free hydroxyl can be reacted to link a plurality of functional groups some or each of which can be reacted to attach directly or via a spacer molecule a moiety containing an aminoxyl-containing radical or to a moiety comprising other drug molecule residue or a moiety comprising other biologically active agent residue.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: December 14, 2004
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Meidong Lang, Chih-Chang Chu
  • Patent number: 6828412
    Abstract: A polymer comprising: a polymeric backbone comprising at least one unit having the structure (I), wherein R-R4 comprise groups selected from the group consisting of H, C1-C12 alkyl, C6-C18 aryl, C7-C18 aralkyl, C6-C18 cycloalkyl or any of the group consisting of C1-C12 alkyl, C6-C18 aryl, C7-C18 aralkyl, C6-C18 cycloalkyl substituted, within the carbon chain or appended thereto, with one or more heteroatoms; R and R2 or R and R4 or R and R1 or R2 and R3 may be joined so that with the carbon atom(s) to which they are attached they together form a saturated, partially unsaturated or unsaturated ring system respectively, may have a pendent group which may incorporate a linker unit, (for example a peptide linkage) or a unit having the structure (I); A comprises a proton donating moiety selected from the group consisting of formula (1).
    Type: Grant
    Filed: July 19, 2002
    Date of Patent: December 7, 2004
    Assignee: School of Pharmacy, University of London
    Inventors: Stephen James Brocchini, Marie-Claude Dubois Clochard
  • Patent number: 6828355
    Abstract: This invention relates to resin-reinforced silicone compositions curable upon exposure to radiation in the electromagnetic spectrum, which compositions when cured demonstrate improved elastomeric properties, such as tensile strength, modulus and elongation. The inventive resin-reinforced silicone compositions may alternatively be rendered curable by exposure to moisture. In addition, the inventive composition may be rendered curable by exposure to radiation in the electromagnetic spectrum, and exposure to moisture. The inventive silicone compositions are particularly well suited for use in electronic conformal coating and potting applications, as well as in automotive gasketing applications, pressure sensitive adhesive applications and the like.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: December 7, 2004
    Assignee: Henkel Corporation
    Inventor: Hsien-Kun Chu
  • Patent number: 6825314
    Abstract: The object of the present invention is to provide a novel method for effectively producing a cyclic lactic acid oligomer, and a cyclic lactic acid oligomer produced by the method.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: November 30, 2004
    Assignee: Amato Pharmaceutical Products, Ltd.
    Inventors: Mikio Watanabe, Jiro Takano, Yoshimi Ishihara, Masahiro Murakami
  • Patent number: 6797788
    Abstract: The invention concerns thermoplastic aliphatic polyester compositions characterized by a melt flow index (RMFI) ranging between 1.1 and 2.5. The invention also concerns a method for preparing said compositions which are used for making films, foams, flasks or thermoformed products. The resulting films obtained from said compositions are used for making litter bags, films for agricultural use, packaging films, shrouds, diaper drawers and adhesive films.
    Type: Grant
    Filed: April 30, 2002
    Date of Patent: September 28, 2004
    Assignee: SOLVAY (Societe Anonyme)
    Inventors: Ivan Claeys, Henri Wautier, Dino Manfredi
  • Patent number: 6794485
    Abstract: An absorbable crystalline, monocentric polyaxial copolymer comprising a central carbon or nitrogen atom and at least three axes, each of which includes an amorphous flexible component adjacent and originating from the central atom and a rigid, crystallizable component extending outwardly from the amorphous, flexible component is disclosed along with the use of such copolymer in medical devices which may contain a bioactive agent. The present invention also relates to a suture, stents, stent mantles and sealing devices made from the polyaxial copolymer.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: September 21, 2004
    Assignee: Poly-Med, Inc.
    Inventors: Shalaby W. Shalaby, Torbjorn Mathisen
  • Patent number: 6794484
    Abstract: The present invention is directed to absorbable polylactone copolymers prepared in part from about 2 to about 80 mole percent glycolide, utilizing a combination of a monofunctional polymerization initiator and a di-functional polymerization initiator, to achieve rates of crystallization of the copolymer of at least about 2 times faster than the rate of crystallization of a copolymer made by a similar process utilizing either the mono-functional or the di-functional polymerization initiator alone. Medical devices containing such copolymers are also disclosed.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: September 21, 2004
    Assignee: Ethicon, Inc.
    Inventors: Hugh D. Newman, Jr., Sasa Andjelic, Brian M. Kelly, Dennis D. Jamiolkowski, Rao S. Bezwada
  • Patent number: 6794462
    Abstract: A composition comprises a solid-stated block copolymer of an aromatic polyester and a caprolactone, wherein the copolymer has been solid state polymerized such that intrinsic viscosity increases at least 20%, the caprolactone content decreases no more than 1.2% absolute and the transesterification increases no more than 3.5% absolute, and wherein the solid-stated copolymer has an intrinsic viscosity of at least 0.82. Particularly preferred chain extension reactions are performed at a temperature of less than 175° C., and even more preferably at less than 165° C. In further aspects of the inventive subject matter, yarns and methods of producing a fiber include contemplated solid-stated block copolymers.
    Type: Grant
    Filed: October 8, 2002
    Date of Patent: September 21, 2004
    Assignee: Honeywell International Inc.
    Inventors: Srinivasan Sridharan, John Armstrong Young, Donald James Arthur, Thomas Yiu-Tai Tam
  • Patent number: 6787613
    Abstract: The invention relates to a mixture of biodegradable polyesters which includes an aromatic-aliphatic polyester (A), an aliphatic polyester (B) and a polyactic acid polymer (C) in which the concentration of A varies, with respect to (A+B) in the range between 40 and 70% by weight, and the concentration of C with respect to (A+B+C) is of between 6 and 30% by weight.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: September 7, 2004
    Assignee: Novamont S.p.A.
    Inventors: Catia Bastioli, Gianfranco Del Tredici, Italo Guanella, Roberto Ponti
  • Patent number: 6774206
    Abstract: The present invention relates to polyaspartates corresponding to the formula wherein X1 represents the residue obtained by removing the amino groups from a polyether polyamine having a functionality of n and a number average molecular weight of less than 600, wherein the amino groups are attached to primary carbon atoms and the ether groups are separated by at least two carbon atoms, R1 and R2 are identical or different and represent organic groups which are inert to isocyanate groups at a temperature of 100° C. or less, R3 and R4 are identical or different and represent hydrogen or organic groups which are inert towards isocyanate groups at a temperature of 100° C. or less and n is 2 to 4. The present invention also relates to polyureas prepared by reacting the polyaspartates and optionally other isocyanate-reactive compounds with polyisocyanates.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: August 10, 2004
    Assignees: Bayer Polymers LLC, Bayer Aktiengesellschaft
    Inventors: Karsten Danielmeier, Catherine M. Britsch, Rolf Gertzmann, Michele E. Vargo, Terrell D. Wayt, Edward P. Squiller
  • Patent number: 6774207
    Abstract: The present invention relates to polyaspartate mixtures containing a) 5 to 70 equiv. %, based on the total equivalents of aspartate groups, of a cyclic polyaspartate corresponding to the formula wherein X1 represents the residue obtained by removing the amino groups from a cyclic polyamine having a functionality of n, R1 and R2 are identical or different and represent organic groups which are inert to isocyanate groups at a temperature of 100° C. or less, R3 and R4 are identical or different and represent hydrogen or organic groups which are inert towards isocyanate groups at a temperature of 100° C. or less and n is 2 to 4, and b) 30 to 95 equiv.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: August 10, 2004
    Assignees: Bayer Polymers LLC, Bayer Aktiengesellschaft
    Inventors: Karsten Danielmeier, Catherine M. Britsch, Rolf Gertzmann, Michele E. Vargo, Terrell Dean Wayt, Edward P. Squiller, Richard R. Roesler
  • Patent number: 6770717
    Abstract: Disclosed is a sequentially ordered biodegradable lactide (or glycolide or lactide/glycolide)/&egr;-caprolactone multi-block copolymers having proper degradation properties and enhanced mechanical properties such as flexibility and elasticity and a process for the preparation thereof.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: August 3, 2004
    Assignee: Korea Institute of Science and Technology
    Inventors: Young Ha Kim, Soo Hyun Kim, Soo-Hong Lee, Oju Jeon