Binds Virus Or Component Or Product Thereof (e.g., Virus-associated Antigen, Etc.) Patents (Class 530/388.3)
Binds retrovirus or component or product thereof (e.g., hiv, lav, htlv, etc.) (Class 530/388.35)
  • Method and kit for detection of dengue virus
    Patent number: 6190859
    Abstract: An inactivated dengue virus vaccine to immunize and protect humans against dengue fever is described. The vaccine is based on dengue viruses which have been propagated to high titers in suitable cells, purified and inactivated under conditions which destroy infectivity but preserve immunogenicity, a high level of which is demonstrated in animal models. Uses of the inactivated dengue virus for detecting antibodies to dengue and kits therefor are also described.
    Type: Grant
    Filed: April 17, 1995
    Date of Patent: February 20, 2001
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: J. Robert Putnak, Kenneth Eckels, Doria R. Dubois, Kevin Cassidy
  • Anticytomegalovirus monoclonal antibodies and processes for the in vitro diagnosis of infections by human cytomegaloviruses and a protein-kinase inducible by cytomegaloviruses and recognizable by aforesaid monoclonal antibodies
    Patent number: 6183754
    Abstract: The invention relates to a process for in vitro diagnosis of an infection by human cytomegaloviruses. The process consists of contacting cells, possibly carrying the infection, with a monoclonal antibody reacting with a polypeptide of molecular weight 68,000, induced by human cytomagalovirus and which possesses a protein-kinase activity. The detection of the reaction is preferably carried out by immunofluorescence.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 6, 2001
    Assignee: Institut Pasteur
    Inventors: Florian Horaud, Susan Michelson, Octavian Barzu, Andre Boue, Clairo Amadei