Quaternary Azo Group Containing Patents (Class 534/574)
  • Patent number: 8623846
    Abstract: A compound having the structure (I) or a pharmaceutically acceptable salt thereof, wherein R3 is hydrogen, deuterium, —OH, —OC1-6alkyl, or halogen; R8 is hydrogen, deuterium, or C1-6alkyl; R11 and R12 are independently hydrogen, —C1-6alkyl, —OH, —OC1-6alkyl, or halogen; R13 and R14 are independently —C1-6alkyl, —(CH2)1-2OH, or —OC1-6alkyl, or, together with the nitrogen atom to which they are attached, form a 4- to 7-membered heterocyclic ring containing one nitrogen atom and 0 or 1 oxygen atoms, wherein said ring is unsubstituted or mono-, di- or tri-substituted with halogen or —C1-6alkyl; R15 is —C(O)OH, —C(O)OCH2CH2N+CH3)3 wherein n is 0, 1 or 2, —C(O)NHCH(R17)OR16, or —C(O)NHCH(R17)C(O)NHCH(R18)C(O)OR16; R16 is hydrogen, C1-6alkyl, or (CH2)1-2N+R19R20R21; R1, R2, R4, R5, R6, R7, R9, R10, R17, R18, R19, R20, and R21 are independently hydrogen or —C1-6alkyl; and stereoisomers thereof, and pharmaceutically acceptable salts thereof, and pharmaceutically acceptable salts of stereoisomers thereof.
    Type: Grant
    Filed: May 16, 2011
    Date of Patent: January 7, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Amjad Ali, Lin Yan, Pei Huo, Ravi Nargund
  • Publication number: 20130059823
    Abstract: A compound having the structure (I) or a pharmaceutically acceptable salt thereof, wherein R3 is hydrogen, deuterium, —OH, —OC1-6alkyl, or halogen; R8 is hydrogen, deuterium, or C1-6alkyl; R11 and R12 are independently hydrogen, —C1-6alkyl, —OH, —OC1-6alkyl, or halogen; R13 and R14 are independently —C1-6alkyl, —(CH2)1-2OH, or —OC1-6alkyl, or, together with the nitrogen atom to which they are attached, form a 4- to 7-membered heterocyclic ring containing one nitrogen atom and 0 or 1 oxygen atoms, wherein said ring is unsubstituted or mono-, di- or tri-substituted with halogen or —C1-6alkyl; R15 is (CR1R2)nC(O)OR16, wherein n is 0, 1 or 2, —C(O)NHCH(R17)OR16, or —C(O)NHCH(R17)C(O)NHCH(R18)C(O)OR16; R16 is hydrogen, C1-6alkyl, or (CH2)1-2N+R19R20R21; R1, R2, R4, R5, R6, R7, R9, R10, R17, R18, R19, R20, and R21 are independently hydrogen or —C1-6alkyl; and stereoisomers thereof, and pharmaceutically acceptable salts thereof, and pharmaceutically acceptable salts of stereoisomers thereof.
    Type: Application
    Filed: May 16, 2011
    Publication date: March 7, 2013
    Inventors: Amjad Ali, Lin Yan, Pei Huo, Ravi Nargund
  • Publication number: 20100154145
    Abstract: Reactive dyes of formula wherein B is an aliphatic bridging member, R1 is C1-C4alkyl, halogen or an —SO2—Z radical, R2 and R3 are each independently of the other C1-C4alkoxy, R4, R5 and R6 are each independently of the others hydrogen or unsubstituted or substituted C1-C4alkyl, k and q are each independently of the other the number 0 or 1, p is the number 0, 1 or 2, X1 and X2 are each independently of the other halogen, and T is halogen, a non-fibre-reactive substituent or a fibre-reactive radical of formula wherein (R7)0-2 denotes from 0 to 2 identical or different substituents from the group halogen, C1-C4alkyl, C1-C4alkoxy and sulfo, Z is vinyl or a —CH2—CH2—U radical and U is a group that is removable under alkaline conditions, Q is a —CH(Hal)-CH2-Hal or —C(Hal)=CH2 group and Hal is halogen, or T is a radical of formula wherein R1, R2, R3, R4, k, p and q each have the definitions given above, are suitable especially for dyeing cotton and yield dyeings having good all-round fastness prop
    Type: Application
    Filed: August 2, 2006
    Publication date: June 24, 2010
    Applicant: HUNTSMAN INTERNATIONAL LLC
    Inventors: Hubert Jean Luc Christnacher, Athanassios Tzikas, Georg Roentgen
  • Publication number: 20080256726
    Abstract: Dye mixtures, comprising at least one dye of formula and at least one dye from the group of formulae wherein B1, B2 and B3 are each independently of the others an organic bridging member, Q1 is C1-C4alkyl, halogen or a radical —SO2-Z, Q2 and Q3 are each independently of the other C1-C4alkoxy, Q4 is C1-C4alkoxy, C1-C4alkyl, halogen or sulfo Q5 is C1-C4alkoxy, C1-C4alkyl, C1-C4alkanoylamino, ureido, halogen or sulfo, R1, R2, R3, R4, R5, R6, R7, R8 and R9 are each independently of the others hydrogen or unsubstituted or substituted C1-C4alkyl, k and q are each independently of the other the number 0 or 1, n and p are each independently of the other the number 0, 1 or 2, m is the number 0, 1, 2 or 3, t is the number 1, 2 or 3, X1, X2, X3, X4, X5 and X6 are each independently of the others halogen, and T1, T2 and T3 are each independently of the others a non-fibre-reactive substituent or a fibre-reactive radical of formula wherein (R10)0-2 denotes from 0 to 2 identical or different substi
    Type: Application
    Filed: November 6, 2006
    Publication date: October 23, 2008
    Inventors: Jean-Marie Sire, Athanassios Tzikas, Georg Roentgen
  • Patent number: 7060806
    Abstract: The cationic dyes of formula (1) specified in claim 1 are suitable especially for colouring keratin-containing fibres, more especially for colouring hair.
    Type: Grant
    Filed: December 8, 2004
    Date of Patent: June 13, 2006
    Assignee: Ciba Specialty Chemicals Corporation
    Inventor: Peter Möckli
  • Patent number: 6620920
    Abstract: The invention provides an optical method which permits, with the aid of 6 simple measurements, a conclusion regarding the suitability of antennas (groups which can absorb electromagnetic radiation) for incorporation into photoaddressable polymers.
    Type: Grant
    Filed: October 14, 1999
    Date of Patent: September 16, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Horst Berneth, Uwe Claussen, Serguei Kostromine, Ralf Neigl, Joachim Rübner, Ralf Ruhmann
  • Patent number: 5554731
    Abstract: Preparation of water-soluble reactive dyes containing vinylsulphonyl and .beta.-sulphatoethylsulphonyl groups by the oxidation of dyes containing .beta.-hydroxyethylmercapto radicals, and then sulphation and, if appropriate, conversion of the .beta.-sulphatoethylsulphonyl radical to the vinylsulphonyl radical with bases.
    Type: Grant
    Filed: September 22, 1994
    Date of Patent: September 10, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl-Josef Herd, Peter Roschger
  • Patent number: 5073634
    Abstract: Basic dyes of the formulaChr.sup..sym.[FeCl.sub.4 ].sup..crclbar.where Chr.sup.a is a dye cation are useful for dyeing acrylonitrile polymers or acid-modified polyesters.
    Type: Grant
    Filed: May 1, 1990
    Date of Patent: December 17, 1991
    Assignee: BASF Aktiengesellschaft
    Inventors: Johannes P. Dix, Guenter Hansen, Hellmut Kast
  • Patent number: 4760132
    Abstract: Cationic hydrazone dyestuffs of the general formula ##STR1## in which R.sub.1 stands for hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.1 - to C.sub.4 -alkoxy, nitro or halogen,R.sub.2 stands for hydrogen, C.sub.1 - to C.sub.4 -alkyl, C.sub.1 - to C.sub.4 -alkoxy, halogen or phenylazo,R.sub.3 stands for C.sub.1 - to C.sub.3 -alkyl andA.sup.- stands for an anion,are prepared by quaternarizing azo bases of the general formula ##STR2## wherein R.sub.1, R.sub.2 and R.sub.3 have the abovementioned meaning, with dialkyl sulphates of the general formula(R.sub.3 --O).sub.2 SO.sub.2 IIIin whichR.sub.3 has the abovementioned meaning,in the presence of water and alkali metal sulphate or alkaline earth metal sulphate and, where appropriate, by replacing the alkylsulphate anion by another anion.
    Type: Grant
    Filed: December 16, 1986
    Date of Patent: July 26, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Lothar Dorsch, Dietmar Kalz, Volker Huhne, Roderich Raue