The Hetero Ring Or A Polycyclo Ring System Which Contains The Hetero Ring As One Of The Cyclos Is Bonded Directly To An Alkylene Chain, Which Chain Is Between The Hetero Ring And The Carbocyclic Ring Patents (Class 534/804)
  • Publication number: 20140073609
    Abstract: Compositions and methods are disclosed in embodiments relating to induction of cell death such as in cancer cells. Compounds and related methods for synthesis and use thereof, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells are disclosed. Compounds are disclosed in connection with modification of procaspases such as procaspase-3. In embodiments, compositions are capable of activation of procaspase-3.
    Type: Application
    Filed: May 14, 2013
    Publication date: March 13, 2014
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Paul J. HERGENROTHER, Karson S. PUTT, Quinn P. PETERSON, Valerie FAKO
  • Patent number: 6297362
    Abstract: Compound of the formula (I) wherein R is hydrogen or optionally substituted C1-C6-alkyl, R1 is hydrogen or C1-C6-alkyl, R2 is hydrogen, optionally substituted C1-C6-alkyl or optionally substituted phenyl, the ring D is optionally substituted by one or more identical or different substituents selected from the group consisting of C1-C6-alkyl, C1-C6-alkoxy, halogen, especially F, Cl and Br, and SO3H, m is 0 or 1, n is 1, 2 or 3 and as a function of n X is a mono-, di- or trivalent acyl radical, pyrimidine or 1,3,5-triazine radical which is not fiber-reactive.
    Type: Grant
    Filed: October 1, 1999
    Date of Patent: October 2, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Kunde, Michael-Thomas Jörss, Peter Wild
  • Patent number: 5827332
    Abstract: Azo dyes of the formula ##STR1## where the ring A may be benzofused,n is 0 or 1, and R.sup.1 -R.sup.8 are as defined,as pH-dependent markers for hydrocarbons, hydrocarbons containing the above-mentioned azo dyes, and a method for detecting these azo dyes in hydrocarbons.
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: October 27, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Georg Zeidler, Gerhard Scholz, Claudia Krah, Karin Heidrun Beck, Udo Mayer
  • Patent number: 5723586
    Abstract: Disperse dyes of the general formula I ##STR1## wherein D signifies a diazo component which is usual with disperse dyes,K signifies an aromatic radical of formula ##STR2## Y signifies ##STR3## and the other symbols have the meanings as defined in claim 1, are useful for dyeing or printing hydrophobic, fully or half-synthetic organic fiber materials.
    Type: Grant
    Filed: June 14, 1996
    Date of Patent: March 3, 1998
    Assignee: Clariant Finance (BVI) Limited
    Inventor: Ruedi Altermatt
  • Patent number: 5710258
    Abstract: The invention relates to compounds of formula ##STR1## The compounds of formula (1) are suitable as dye for dyeing or printing hydroxyl group-containing or nitrogen-containing fibre materials and give dyeings of prints having good allround fastness properties.
    Type: Grant
    Filed: February 5, 1996
    Date of Patent: January 20, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Jean-Marie Adam, Peter Sutter
  • Patent number: 5633355
    Abstract: The disperse dyes of formula I ##STR1## wherein the symbols D, K, R.sub.3-5, R.sub.10, m, z, n and Y possess the significances given in claim 1, are eminently suitable for dyeing or printing hydrophobic, fully or semi-synthetic, organic fiber materials.
    Type: Grant
    Filed: November 7, 1995
    Date of Patent: May 27, 1997
    Assignee: Sandoz Ltd.
    Inventor: Ruedi Altermatt
  • Patent number: 5466282
    Abstract: Disclosed herein is a monoazo dye compound having a structural unit represented by the following formula in its molecule:--X--Y--(R.sub.1)(R.sub.2)(R.sub.3).sub.k [I]wherein Y is a 6-membered ring containing 2 or 3 nitrogen atoms, X is a linking group for bonding a main body of the dye molecule to Y, R.sub.1 is the first amino acid residue, R.sub.2 is an atomic group selected from the following group A, R.sub.3 is another atomic group selected from the following group BB, and k is a number of 0 or 1:Group A: H, OH, NH.sub.2, CN, .dbd.O and the second amino acid residue;Group BB: H, OH, NH.sub.2, CN and .dbd.O,the first and second amino acid residues being identical with or different from each other.
    Type: Grant
    Filed: May 12, 1994
    Date of Patent: November 14, 1995
    Assignee: Canon Kabushiki Kaisha
    Inventors: Tsuyoshi Eida, Osamu Nishiwaki, Takao Yamamoto, Kumiko Mafune
  • Patent number: 4962190
    Abstract: Polyethyleneimine-containing azo dyes of the formula[(D-N=N-K-).sub.y X-].sub.m PwhereD is the radical of a diazo component which is derived from an isocyclic aromatic amine or from a heteroaromatic amine and is free of hydroxysulfonyl groups,K is the radical of a coupling component of the hydroxynaphthalene, aminopyridine or pyrazolone series which has at most one hydroxysulfonyl group, or is the radical of a coupling component derived from acetoacetic acid,y is 1 or 2,X is a covalent bond or a bridge member if y is 1 or a bridge member if y is 2, andP is the radical of a polyethyleneimine whose degree of polymerization n is from 5 to 25000,and the number m of chromophore radicals is dependent upon the degree of polymerization n and is defined by the ratio m:n=from 1:1 to 1:35, with the proviso that when K is substituted by hydroxysulfonyl the ratio m:n is from 1:2 to 1:35, are useful for dyeing or printing fiber materials and for preparing inks for the ink jet process.
    Type: Grant
    Filed: November 21, 1988
    Date of Patent: October 9, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Udo Mayer, Friedrich-Wilhelm Raulfs
  • Patent number: 4935499
    Abstract: Paper is colored by a process in which a compound which, in the form of the free acid, is of the formula I ##STR1## where, in each case independently of one another, A is unsubstituted or methyl substituted C.sub.1 -C.sub.6 -alkylene or vinylene,R is each hydrogen or C.sub.1 -C.sub.4 -alkyl,X is each --CO-- or --SO.sub.2 --,K is each a cationic group andY is hydrogen, chlorine or bromine.
    Type: Grant
    Filed: September 27, 1988
    Date of Patent: June 19, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Manfred Ruske, Hans-Juergen Degen
  • Patent number: 4913997
    Abstract: This provides an electrophotographic photoreceptor high in durability and sensitivity which comprises an electroconductive support and, provided thereon, a photosensitive layer containing an azo pigment represented by the formula [I]: ##STR1## wherein A represents an aryl group, a heterocyclic group or an alkyl group, Z represents a hydrogen atom, --B or --CH.dbd.CH--B wherein B represents an aryl group, a heterocyclic group or an alkyl group and Cp represents a coupler residue.
    Type: Grant
    Filed: January 12, 1989
    Date of Patent: April 3, 1990
    Assignee: Mitsubishi Paper Mills Limited
    Inventors: Kazuhiro Emoto, Kozo Haino
  • Patent number: 4810783
    Abstract: An azo dyestuff of the formula ##STR1## wherein D=a diazo component,R.sub.1 and R.sub.2 =alkyl or aralkyl,R.sub.3 =H, R or OR.sub.1 andR.sub.4 =a hydrocarbon radical or acyl,which are prepared in a simple manner by aminolysis with ammonia or an amine of the formula ##STR2## of an azo compound of the formula ##STR3## these dyestuffs dye polyester fibres in blue-green to green shades with good fastness to light.
    Type: Grant
    Filed: March 3, 1987
    Date of Patent: March 7, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventor: Klaus Leverenz
  • Patent number: 4769448
    Abstract: An electrically conductive liquid crystalline substance represented by the general formula L-S.sub.1 -C.sub.T or L-C.sub.T, wherein L is a residue of a liquid crystalline substance, S.sub.1 is an atom or atomic grouping which becomes a spacer and C.sub.T is a charge-transfer complex, is disclosed. An electrically conductive liquid crystalline polymer having an electrically conductive liquid crystalline substance portion in its side chain is also provided. These electrically conductive liquid crystalline materials are useful in the conventional applications of liquid crystals and in other applications which utilize their electrical conductivity.
    Type: Grant
    Filed: December 2, 1986
    Date of Patent: September 6, 1988
    Assignee: Showa Denko Kabushiki Kaisha
    Inventors: Alan J. Heeger, Haruo Yoshida, Kazumi Naito, Yukio Kobayashi
  • Patent number: 4769447
    Abstract: The present invention provides gamma-glutamyl-4-azoanilides, processes for their preparation and their use as substrates for gamma-glutamyl transferase determination, of the formula ##STR1## wherein X is alkyl, --(CH.sub.2).sub.m --COOH or --O--(CH.sub.2).sub.n --COOH wherein m is 0-4 and n is 1-4; R is optionally substituted p-nitrophenyl; an optionally substituted thiophene residue; an optionally substituted thiazole residue; an optionally substituted benzothiazole residue; an optionally substituted benzoisothiazole residue; an N-alkylthiazole residue; or an optionally substituted 1,3,5-thiodiazole residue; as well as the alkali metal, alkaline earth metal and ammonium salts thereof.
    Type: Grant
    Filed: January 27, 1987
    Date of Patent: September 6, 1988
    Assignee: Boehringer Mannheim GmbH
    Inventors: Elli Rauscher, John Griffiths, Leonard F. Dixon