Conversion Of Amine Salts To Metal Salts Patents (Class 540/321)
  • Publication number: 20020137926
    Abstract: A novel process for preparing a crystalline alkali metal salt of amoxycillin is dislcosed.
    Type: Application
    Filed: February 13, 2002
    Publication date: September 26, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Esin F. Kosal, Paul G. Butterly
  • Patent number: 4737585
    Abstract: Sodium amoxycillin, of use for example by parenteral administration, is prepared by:(a) suspending amoxycillin trihydrate in a mixture comprising an aprotic organic solvent and a lower alcohol;(b) solubilizing the amoxycillin trihydrate by the addition of a low molecular weight amine of the group of cyclic or heterocyclic aliphatics;(c) adding to such solution the sodium salt of diethyloxalacetic acid, agitating the reaction mixture at a temperature of from -10.degree. C. to ambient temperature and finally isolating the sodium amoxycillin by filtration after its precipitation in the reaction medium by the addition of an aprotic organic solvent.
    Type: Grant
    Filed: October 21, 1986
    Date of Patent: April 12, 1988
    Assignee: Antibioticos S.A.
    Inventors: Augustin Perez-Aranda Ortega, Santiago C. Ruzafa, Fernando R. Serra
  • Patent number: 4510485
    Abstract: A sound generating device for a jogger has a generator circuit for generating pace signals the frequencies of which are different from each other in correspondence with different tempos and for generating reference clock pulses, a time counter for receiving and counting the reference clock pulses, and circuits for selectively supplying pace signals the frequencies of which are different from each other and which are supplied from the generator circuit. In response to an instruction signal generated by a switching operation, the time counter starts counting. Simultaneously, based on a selected pace signal from the generator circuit, a desired pace sound can be produced.
    Type: Grant
    Filed: August 21, 1984
    Date of Patent: April 9, 1985
    Assignee: Casio Computer Co., Ltd.
    Inventor: Iwao Tahara