Polycyclo Heterocyclic Ring System In 6-position Substituent Patents (Class 540/329)
The polycyclo ring system is attached directly to a -c(=x)-nh- group, wherein x is chalcogen and substitution may be made for hydrogen only, which group is between the polycyclo ring system and the 1-thia-4-aza bicyclo(3.2.0)hep-tane (Class 540/330)
  • Compositions and methods for modification of biomolecules
    Patent number: 8431558
    Abstract: The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions. In general, the invention involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids).
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: April 30, 2013
    Assignee: The Regents of the University of California
    Inventors: Carolyn Ruth Bertozzi, Nicholas J. Agard, Jennifer A. Prescher, Jeremy Michael Baskin, Ellen May Sletten
  • Substituted pyridines/pyrimidines, their preparation, and their use as pesticides
    Patent number: 6207668
    Abstract: The present invention relates to novel substituted pyridines/pyrimidines of the formula I where A is CH or N; X is NH, oxygen or S(O)q where q is 0, 1 or 2; Y is a direct bond or CH2; Z is oxygen, NR7 or S(O)m is 0, 1 or 2, and the radicals R1, R2, R3, R4, R5, R6 and R7 are as defined in the description, to processes for their preparation, and to their use as pesticides, fungicides, ovicides or as veterinary medicaments.
    Type: Grant
    Filed: April 1, 1997
    Date of Patent: March 27, 2001
    Assignee: Hoechst Schering
    Inventors: Ralf Braun, Wolfgang Schaper, Werner Knauf, Ulrich Sanft, Manfred Kern, Werner Bonin
  • 2-(Allenyl)penicillins
    Patent number: 4769325
    Abstract: 2-(Allenyl)penicillins antibiotics and intermediates thereto are disclosed. A process for making the 2-(allenyl)penicillins and the starting materials for the process are also disclosed.
    Type: Grant
    Filed: July 28, 1986
    Date of Patent: September 6, 1988
    Inventors: Jack E. Baldwin, Amit Basak
  • Derivatives of .beta.-(4-isocyano-1,2,3,4-diepoxycyclopentyl) acrylic acid
    Patent number: 4684664
    Abstract: Disclosed herein are derivatives of .beta.-(4-isocyano-1,2,3,4-diepoxycyclopentyl)acrylic acid, the derivatives showing an antibacterial activity, an antifungal activity and an antimycoplasmal activity.
    Type: Grant
    Filed: January 16, 1985
    Date of Patent: August 4, 1987
    Assignee: Kureha Kagaku Kogyo Kabushiki Kaisha
    Inventors: Katsuhisa Osugi, Isao Ichinose, Eisaku Takahashi, Masato Arahira
  • Acylation of tirandamycic, streptolic and sorbic acids to cephalosporin and penicillin nuclei
    Patent number: 4623644
    Abstract: This invention relates to the hybridization of streptolydigin, tirandamycin and sorbic acid to penicillin and cephalosporin nuclei.
    Type: Grant
    Filed: August 7, 1985
    Date of Patent: November 18, 1986
    Assignee: The Upjohn Company
    Inventors: Fritz Reusser, Kenneth L. Rinehart, Jr.