Abstract: An improved process for the production of penicillic acid compounds, especially chloromethyl ester of penicillin G, penicillin V or sulbactam is disclosed.
Abstract: .beta.-Lactam antibiotics having an .alpha.-formamido substituent on the carbon atom adjacent to the carbonyl group of the .beta.-lactam ring and in particular bicyclic compounds having the partial structure: ##STR1## Intermediates and processes for the preparation of the compounds are further disclosed.