Chalcogen In The Chain Between The Ring And The -c(=x)- Group Patents (Class 540/341)
  • Beta-lactamase inhibitor prodrug
    Publication number: 20040110740
    Abstract: Prodrugs of 6-&bgr;-hydroxymethylpenicillanic acid sulfone having the structure 1
    Type: Application
    Filed: August 25, 2003
    Publication date: June 10, 2004
    Applicant: Pfizer Inc
    Inventors: Anthony Marfat, Dale G. McLeod
  • Naphthalene derivatives, processes for preparing the same, and synthetic intermediates therefor
    Patent number: 5342941
    Abstract: Naphthalene derivative of the formula [I]: ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are hydrogen atom, hydroxy group, cyclo-lower alkyloxy group, substituted or unsubstituted lower alkoxy group, or both combine each other to form lower alkylenedioxy group, R.sup.3 is substituted or unsubstituted nitrogen-containing 6-membered heterocyclic group, and groups of the formulae: --OR.sup.4 and --OR.sup.5 are the same or different and are protected or unprotected hydroxy group, processes for preparing thereof, and synthetic intermediates therefor, these compounds have excellent bronchodilating activity, and are useful in the prophylaxis and treatment of asthma.
    Type: Grant
    Filed: February 19, 1993
    Date of Patent: August 30, 1994
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Tameo Iwasaki, Kazuhiko Kondo, Katsuo Ikezawa, Hideo Kikkawa, Shinsuke Yamagata
  • Methods of using .beta.-lactam antibacterial agents
    Patent number: 4609652
    Abstract: .beta.-Lactam antibiotics having an .alpha.-formamido substituent on the carbon atom adjacent to the carbonyl group of the .beta.-lactam ring and in particular bicyclic compounds having the partial structure: ##STR1## Intermediates and processes for the preparation of the compounds are further disclosed.
    Type: Grant
    Filed: January 24, 1985
    Date of Patent: September 2, 1986
    Assignee: Beecham Group p.l.c.
    Inventor: Peter H. Milner