Nitrogen Containing Hetero Ring As One Of The Cyclos Of The Polycyclo Ring System Patents (Class 540/9)
  • Preparation and application of propargyl ether-containing benzoxazine with high-TG characteristic
    Patent number: 8802846
    Abstract: The present invention provides benzoxazine containing propargyl group as formula (I): wherein and The present invention provides a method of preparing a compound of formula (I). The present invention also provides a flame resistant resin.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: August 12, 2014
    Assignee: Chung Shan Institute of Science and Technology, Armaments Bureau, M.N.D
    Inventors: Wen-Chiung Su, Ching-Hsuann Lin, Chu-Ming Huang
  • DNA minor groove binding compounds
    Patent number: 7700765
    Abstract: There is provided an oligopeptide compound comprising: (a) at least one nitrogen-containing basic group attached to at least one end of the oligopeptide; and (b) two or more heterocyclic monomers, at least one of which is substituted in the heterocyclic part by a branched, cyclic or part cyclic C3-5 alkyl group, or a pharmaceutically acceptable salt or solvate thereof; which compound, salt or solvate binds to the minor groove of DNA.
    Type: Grant
    Filed: December 24, 2002
    Date of Patent: April 20, 2010
    Assignee: University of Strathclyde
    Inventors: Abedawn Khalaf, Roger Waigh, Colin Suckling
  • 17-spiromethylene steroids
    Patent number: 5854235
    Abstract: The invention relates to a steroid derivative which steroidal skeleton is bound at carbon atom 17 to a spiromethylene ring of the formula: ##STR1## wherein R.sub.a and R.sub.b are independently selected from the group consisting of hydrogen, methyl, and halogen; m is 1 or 2; and the asterisk denotes carbon atom 2 of the spiromethylene ring which is carbon atom 17 (or carbon atom 17.alpha. of a homosteroid skeleton) of the steroid. The steroids have progestational or antiprogestational activity.
    Type: Grant
    Filed: November 3, 1997
    Date of Patent: December 29, 1998
    Assignee: Akzo Nobel N.V.
    Inventors: Johannes Antonius Maria Hamersma, Everardus Otto Maria Orlemans, Johannes Bernardus Maria Rewinkel
  • Cephalostatin analogues
    Patent number: 5708164
    Abstract: Synthetically produced cephalostatin analogues of the formula I described in the disclosure, synthetic methods for preparing the cephalostatin analogues, pharmaceutical compositions containing the analogues and methods for using the analogues as active agent in pharmaceutical uses, particularly due to their cytotoxic activity.
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: January 13, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Ekkehard Winterfeldt, Andreas Kramer, Ulrike Ullmann, Henry Laurent
  • .DELTA..sup.9(11) -angiostatic steroids
    Patent number: 4975537
    Abstract: Disclosed are .DELTA..sup.9(11) -steroids of the formula ##STR1## which have been found to be angiostatic and therefore are useful in the control of embryogenesis, inflammatory conditions, tumor growth as well as other abnormalities.
    Type: Grant
    Filed: May 15, 1989
    Date of Patent: December 4, 1990
    Assignee: The Upjohn Company
    Inventors: Paul A. Aristoff, Harvey I. Skulnick, Wendell Wierenga