Pteridines (including Hydrogenated) Patents (Class 544/257)
Nitrogen bonded directly to the pteridine ring system (Class 544/258)
  • Radioassay of folates
    Patent number: 4136159
    Abstract: Novel folic acid derivatives useful in processes for analysis of biological fluids for folic acid or its metabolites comprising components of the formula: ##STR1## wherein R is hydrogen or radioactive iodine.
    Type: Grant
    Filed: February 28, 1977
    Date of Patent: January 23, 1979
    Assignee: New England Nuclear Corporation
    Inventor: Marcia J. Stone
  • 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for the preparation thereof
    Patent number: 4113867
    Abstract: 2-Acyl-4-oxo-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives of the formula ##STR1## wherein COR is the acyl radical of an up to 26 carbon atom acid and their physiologically acceptable acid addition and quaternary ammonium salts, are anthelmintics and can be produced by reacting 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline with an acid or a reactive functional derivative thereof.
    Type: Grant
    Filed: November 15, 1976
    Date of Patent: September 12, 1978
    Assignee: Merck Patent Gesellschaft mit Beschrankter Haftung
    Inventors: Jurgen Seubert, Herbert Thomas, Peter Andrews