Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
Type:
Grant
Filed:
June 7, 1977
Date of Patent:
December 26, 1978
Assignees:
Mitsubishi Chemical Industries, Limited, Shosuke Okamoto
Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
Type:
Grant
Filed:
October 21, 1977
Date of Patent:
September 26, 1978
Assignees:
Mitsubishi Chemical Industries Ltd., Shosuke Okamoto
Abstract: 2-Acyl-4-oxo-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives of the formula ##STR1## wherein COR is the acyl radical of an up to 26 carbon atom acid and their physiologically acceptable acid addition and quaternary ammonium salts, are anthelmintics and can be produced by reacting 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline with an acid or a reactive functional derivative thereof.
Type:
Grant
Filed:
November 15, 1976
Date of Patent:
September 12, 1978
Assignee:
Merck Patent Gesellschaft mit Beschrankter Haftung
Inventors:
Jurgen Seubert, Herbert Thomas, Peter Andrews
Abstract: N.sup.2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.
Type:
Grant
Filed:
January 19, 1977
Date of Patent:
June 6, 1978
Assignees:
Mitsubishi Chemical Industries Limited, Shosuke Okamoto