Abstract: Chemical agents, such as disulfonamide derivatives of fluorene, anthracene, xanthene, dibenzosuberone and acridine, and similar heterocyclic ring structures, including salts thereof, that act as anti-cancer and anti-tumor agents, especially where such agents modulate the activity of the Wnt/?-catenin signaling pathway, and serve to reduce ?-catenin levels present in cells, such as cancer cells, or where the agents modulate levels of gene expression in cellular systems, including cancer cells, are disclosed, along with methods for preparing such agents, as well as pharmaceutical compositions containing such agents as active ingredients and methods of using these as therapeutic agents.

Abstract: The present invention relates to a method for the production of a dye preparation from madder root, comprising extraction of madder root in water at a temperature below 70-75° C., preferably below 65° C., while providing oxygen to the reaction mixture of madder root in water to obtain the dye preparation and to the dye preparation thus obtained.

Abstract: Dye salts which are free from fiber-reactive radicals and have the formula where Chr is an (m+n)-valent radical of a chromophore from the series of the metal-free or metal-containing phthalocyanines, of the quinacridones, of the mono-, dis- or polyazo dyes, of the anthraquinones or copper formazans, Ar is phenyl or naphthyl each of which is unsubstituted or substituted, x⊕ is a metal cation or ammonium ion, y⊕ is a proton, metal cation or ammonium ion, m is 1 to 6 and n is 1 to 6, the sum of m and n being not more than 7, are used in methods of dyeing or printing polymeric material and in dye preparations.

Abstract: Anthraquinone compounds inhibit methane production by methanogenic bacteria in the rumen of ruminant animals, increasing production of volatile fatty acids and feed utilization efficiency. Preferred anthraquinones are unsubstituted anthraquinone, 1-aminoanthraquinone, 1-chloroanthraquinone, 2-chloroanthraquinone, 2-chloro-3-carboxyanthraquinone, 1-hydroxyanthraquinone, and 9,10-dihydroanthraquinone.

Abstract: p-Dihydroxylated aromatic compounds are prepared via the oxidation of p-fuchsones, the latter advantageously being synthesized by reacting a phenolic compound having at least one hydrogen atom in the para-position to the hydroxyl function with a non-enolizable ketonic compound, in the presence of a catalytically effective amount of an acid catalyst and, optionally, a cocatalytically effective amount of an ionizable sulfur-containing compound.

Abstract: The present invention relates to a process for producing an aromatic nitro compound by introducing a nitrogen oxide gas and ozone-containing oxygen or air into a halogenated organic solvent dissolving or suspending therein an aromatic compound, thereby subjecting the aromatic compound to nitration. By the use of a system comprising the nitrogen oxide and ozone-containing oxygen or air as the nitrating agent, the aromatic nitro compound can be produced under mild conditions without using any mineral acid. In addition, the various disadvantages due to the use of mineral acid in the conventional process can be avoided by the process of the present invention.

Abstract: A novel tetracyanoanthraquinodimethane derivative and a process for producing it are disclosed, the tetracyanoanthraquinodimethane derivative being represented by formula: ##STR1## wherein R, m, and n are as defined in the specification. A solid charge transfer complex of the tetracyanoanthraquinodimethane derivative with an electron donating compound and a process for producing it are also disclosed.

Abstract: A novel tetracyanoanthraquinodimethane derivative and a process for producing it are disclosed, the tetracyanoanthraquinodimethane derivative being represented by formula: ##STR1## wherein R, m, and n are as defined in the specification. A solid charge transfer complex of the tetracyanoanthraquinodimethane derivative with an electron donating compound and a process for producing it are also disclosed.