The Polycyclo Ring System Has Five Of Six Cyclos Patents (Class 552/284)
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Patent number: 8759554Abstract: Compounds containing arylalkynyl groups with multiple ring bridging, the use of those compounds in electronic devices, and electronic devices containing the compounds.Type: GrantFiled: June 17, 2010Date of Patent: June 24, 2014Assignee: Merck Patent GmbHInventors: Rocco Fortte, Amir Hossain Parham, Teresa Mujica-Fernaud
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Publication number: 20120115819Abstract: The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I) and its therapeutic use.Type: ApplicationFiled: May 13, 2010Publication date: May 10, 2012Inventors: Roger B. Clark, Diana Katharine Hunt, Louis Plamondon, Cuixiang Sun, Xiao-Yi Xiao, Magnus P. Rönn
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Patent number: 8124799Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.Type: GrantFiled: April 20, 2009Date of Patent: February 28, 2012Assignee: Reata Pharmaceuticals, Inc.Inventors: Eric Anderson, Xin Jiang, Melean Visnick
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Patent number: 7935836Abstract: The present application discloses methods for the production of organic compounds comprising a linear series of five fused carbon rings. Such compounds are useful in the production of electronic components, devices and materials. For example the methods disclosed permit the production of 2,9- and 2,10-disubstituted pentacene compounds and 2,6,9,13- and 2,6,10,13-tetrasubstituted compounds that present particularly advantageous properties for the manufacture of semiconductor materials, and may be used in devices such as for example thin film transistors and solar cells. These features are enhanced by ?-? parallel stacking in the solid state. Also disclosed are compounds that are excellent candidates for use in the manufacture of semiconductor materials, and other components of electronic systems, by virtue of their solubility, crystal packing geometries, and electronic properties.Type: GrantFiled: August 6, 2009Date of Patent: May 3, 2011Inventor: Alexander Graham Fallis
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Publication number: 20100130451Abstract: The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The modular synthesis of tetracyclines and tetracycline analogs described provides an efficient and enantioselective route to a variety of tetracycline analogs and polycyclines previously inaccessible via earlier tetra-cycline syntheses and semi-synthetic methods. These analogs may be used as anti-microbial agents or anti-pro liferative agents in the treatment of diseases of humans or other animals.Type: ApplicationFiled: April 6, 2007Publication date: May 27, 2010Applicant: Presidents and Fellows of Harvard CollegeInventors: Andrew G. Myers, Jason D. Brubaker, Cuixiang Sun, Qiu Wang
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Patent number: 7655809Abstract: The present application discloses methods for the production of organic compounds comprising a linear series of five fused carbon rings. Such compounds are useful in the production of electronic components, devices and materials. For example the methods disclosed permit the production of 2,9- and 2,10-disubstituted pentacene compounds that present particularly advantageous properties for the manufacture of semiconductor materials, and may be used in devices such as for example thin film transistors and solar cells. Also disclosed are compounds that are excellent candidates for use in the manufacture of semiconductor materials, and other components of electronic systems, by virtue of their solubility, crystal packing geometries, and electronic properties.Type: GrantFiled: May 17, 2005Date of Patent: February 2, 2010Assignee: University of OttawaInventors: Alexander Graham Fallis, Matthew Allen Heuft, Christophe Bénard
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Patent number: 7479181Abstract: An inkjet ink composition consists essentially of a vehicle and an effective amount pigment red 168.Type: GrantFiled: July 31, 2006Date of Patent: January 20, 2009Assignee: Hewlett-Packard Development Company, L.P.Inventors: Howard A. Doumaux, Kathryn Nifong Burns, David M. Mahli
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Patent number: 7452385Abstract: The agent for coloring keratin fibers, especially human hair, contains at least one common cosmetic additive; an oxidant, such as hydrogen peroxide; and at least one naphthalene derivative of formula (I): wherein A1 and A2 are different from each other and, independently of each other, each denote a partial structure of formula (II), (IIIa), (IIIb), (IV), (V), or (VI): E is O or S; Y is N or a quaternary nitrogen atom substituted with a C1-C6-alkyl group, a C2-C4-hydroxyalkyl group, or a C4-C6-polyhydroxyalkyl group. New naphthalene derivatives are also described.Type: GrantFiled: October 20, 2004Date of Patent: November 18, 2008Assignee: Wella AGInventors: Markus Speckbacher, Hans-Juergen Braun
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Publication number: 20080022889Abstract: An inkjet ink composition consists essentially of a vehicle and an effective amount pigment red 168.Type: ApplicationFiled: July 31, 2006Publication date: January 31, 2008Inventors: Howard A. Doumaux, Kathryn Nifong Burns, David M. Mahli
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Patent number: 7270700Abstract: A composition comprising: (a) a compound of Formula (1) wherein: R1, R2, R3 and R4 independently are substituents; m and p independently are 0 to 3; and n and q independently are 0 to 2: provided that the compound of Formula (1) comprises at least one water solubilising group; and (b) a liquid media. Also novel compounds and ink-jet printer inks, processes and cartridges.Type: GrantFiled: December 2, 2005Date of Patent: September 18, 2007Assignee: Fujifilm Imaging Colorants LimitedInventor: Clive Edwin Foster
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Patent number: 7157477Abstract: The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these compositions are disclosed. The present invention relates to the field of photosensitizers possessing photodynamic activities. They possess high photodynamic activities and low dark toxicities, which makes them as more potent photodynamic agents than HPD against cancer and AIDS virus.Type: GrantFiled: October 24, 2001Date of Patent: January 2, 2007Assignees: Altachem Pharma Ltd., Institute of Photographic Chemistry Academia SinicaInventors: Manhua Zhang, Shangjie Xu, Tao Wu, Shen Chen, Tao Shen
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Patent number: 6891063Abstract: Salts of asiatic and madecassic acid with pharmaceutically acceptable organic bases, suitable for the preparation of pharmaceutical and cosmetic compositions for the topical and systemic treatment of erithema, varicose ulcers, venous insufficiency, bedsores, delayed cicatrization, ambustions, traumatic and surgery wounds, alloeosises of the cutaneous trophism, ophthalmic alloeosises and inflammatory processes.Type: GrantFiled: April 19, 2000Date of Patent: May 10, 2005Assignee: Euphar Group S.r.l.Inventors: Paolo Corvi Mora, Angelo Ranise
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Publication number: 20040092557Abstract: The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these compositions are disclosed. The present invention relates to the field of photosensitizers possessing photodynamic activities. They possess high photodynamic activities and low dark toxicities, which makes them as more potent photodynamic agents than HPD against cancer and AIDS virus.Type: ApplicationFiled: August 26, 2003Publication date: May 13, 2004Inventors: Manhua Zhang, Shangjie Xu, Tao Wu, Shen Chen, Tao Shen
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Patent number: 6562121Abstract: Organic pigments are conditioned by introducing a liquid prepigment suspension into a miniaturized continuous reactor and thermally treating therein.Type: GrantFiled: June 27, 2001Date of Patent: May 13, 2003Assignee: Clariant Finance (BVI) LimitedInventors: Uwe Nickel, Klaus Kund, Erwin Dietz, Joachim Weber, Olaf Schupp
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Patent number: 6344153Abstract: The present invention provides liquid crystal having a spiral coil structure and a dipole moment along its axis and a helical discotic switch using the same, wherein the helicene compound has the structure: wherein X is O, or S and Y is —O—C(═O)CH2—O—R5, wherein R5 is H, substituted or unsubstituted alkyl, alkenyl, cycloalkyl, aryl, or arylalkyl, wherein R1, R2, R3 and R4 are independently the same or different and are substituted or unsubstituted alkyl, alkenyl, cycloalkyl, aryl, or arylalkyl.Type: GrantFiled: August 27, 1999Date of Patent: February 5, 2002Assignee: The Trustees of Columbia University in the City of New YorkInventors: Thomas J. Katz, Colin P. Nuckolls
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Patent number: 5326867Abstract: The present invention relates to intermediates, pradimic acids and pradimic acid amides of the formula (II) ##STR1## wherein R is OH or NH.sub.2 ; R.sup.1 is hydrogen or a group of the formula ##STR2## with the proviso that when R is OH, R.sup.1 is not hydrogen; Y is OH or NR.sup.2 R.sup.3 ; R.sup.2 is hydrogen or methyl; R.sup.3 is hydrogen, C.sub.1-5 alkyl, or an amino protecting group; R.sup.4 is hydrogen, hydroxy protecting group, or .beta.-D-xylosyl. The invention relates also to novel processes for the preparation of pradimic acids and pradimic acid amides, as well as novel pradimicin derivatives prepared therefrom.Type: GrantFiled: July 16, 1992Date of Patent: July 5, 1994Assignee: Bristol-Myers Squibb CompanyInventors: Satsuki Okuyama, Takaaki Okita, Hajime Kamachi
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Patent number: 5035747Abstract: Mixed crystal pigments of the anthanthrone series and preparation and use thereof Mixed crystal pigments of the anthanthrone series formed from two or more compounds of the formula I ##STR1## where R.sub.1 and R.sub.2 are each hydrogen, chlorine, bromine, iodine, nitro, cyano, amino, hydroxyl, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, aryloxy, C.sub.1 -C.sub.4 -alkylsulfonyl, benzylsulfonyl, acetoxy, anilino, naphthindonylamino or phthalimido, wherein each component may be present in an amount of 1-99%, the preparation thereof by revatting, bead milling, dry milling, dissolving in inorganic acid and precipitating by pouring into water, and use thereof for pigmenting high molecular weight natural or synthetic organic materials.Type: GrantFiled: December 22, 1989Date of Patent: July 30, 1991Assignee: Hoechst AktiengesellschaftInventors: Erwin Dietz, Manfred Urban