The Polycyclo Ring System Has Five Of Six Cyclos Patents (Class 552/284)
  • Patent number: 8759554
    Abstract: Compounds containing arylalkynyl groups with multiple ring bridging, the use of those compounds in electronic devices, and electronic devices containing the compounds.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: June 24, 2014
    Assignee: Merck Patent GmbH
    Inventors: Rocco Fortte, Amir Hossain Parham, Teresa Mujica-Fernaud
  • Publication number: 20120115819
    Abstract: The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I) and its therapeutic use.
    Type: Application
    Filed: May 13, 2010
    Publication date: May 10, 2012
    Inventors: Roger B. Clark, Diana Katharine Hunt, Louis Plamondon, Cuixiang Sun, Xiao-Yi Xiao, Magnus P. Rönn
  • Patent number: 8124799
    Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: February 28, 2012
    Assignee: Reata Pharmaceuticals, Inc.
    Inventors: Eric Anderson, Xin Jiang, Melean Visnick
  • Patent number: 7935836
    Abstract: The present application discloses methods for the production of organic compounds comprising a linear series of five fused carbon rings. Such compounds are useful in the production of electronic components, devices and materials. For example the methods disclosed permit the production of 2,9- and 2,10-disubstituted pentacene compounds and 2,6,9,13- and 2,6,10,13-tetrasubstituted compounds that present particularly advantageous properties for the manufacture of semiconductor materials, and may be used in devices such as for example thin film transistors and solar cells. These features are enhanced by ?-? parallel stacking in the solid state. Also disclosed are compounds that are excellent candidates for use in the manufacture of semiconductor materials, and other components of electronic systems, by virtue of their solubility, crystal packing geometries, and electronic properties.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: May 3, 2011
    Inventor: Alexander Graham Fallis
  • Publication number: 20100130451
    Abstract: The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The modular synthesis of tetracyclines and tetracycline analogs described provides an efficient and enantioselective route to a variety of tetracycline analogs and polycyclines previously inaccessible via earlier tetra-cycline syntheses and semi-synthetic methods. These analogs may be used as anti-microbial agents or anti-pro liferative agents in the treatment of diseases of humans or other animals.
    Type: Application
    Filed: April 6, 2007
    Publication date: May 27, 2010
    Applicant: Presidents and Fellows of Harvard College
    Inventors: Andrew G. Myers, Jason D. Brubaker, Cuixiang Sun, Qiu Wang
  • Patent number: 7655809
    Abstract: The present application discloses methods for the production of organic compounds comprising a linear series of five fused carbon rings. Such compounds are useful in the production of electronic components, devices and materials. For example the methods disclosed permit the production of 2,9- and 2,10-disubstituted pentacene compounds that present particularly advantageous properties for the manufacture of semiconductor materials, and may be used in devices such as for example thin film transistors and solar cells. Also disclosed are compounds that are excellent candidates for use in the manufacture of semiconductor materials, and other components of electronic systems, by virtue of their solubility, crystal packing geometries, and electronic properties.
    Type: Grant
    Filed: May 17, 2005
    Date of Patent: February 2, 2010
    Assignee: University of Ottawa
    Inventors: Alexander Graham Fallis, Matthew Allen Heuft, Christophe Bénard
  • Patent number: 7479181
    Abstract: An inkjet ink composition consists essentially of a vehicle and an effective amount pigment red 168.
    Type: Grant
    Filed: July 31, 2006
    Date of Patent: January 20, 2009
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Howard A. Doumaux, Kathryn Nifong Burns, David M. Mahli
  • Patent number: 7452385
    Abstract: The agent for coloring keratin fibers, especially human hair, contains at least one common cosmetic additive; an oxidant, such as hydrogen peroxide; and at least one naphthalene derivative of formula (I): wherein A1 and A2 are different from each other and, independently of each other, each denote a partial structure of formula (II), (IIIa), (IIIb), (IV), (V), or (VI): E is O or S; Y is N or a quaternary nitrogen atom substituted with a C1-C6-alkyl group, a C2-C4-hydroxyalkyl group, or a C4-C6-polyhydroxyalkyl group. New naphthalene derivatives are also described.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: November 18, 2008
    Assignee: Wella AG
    Inventors: Markus Speckbacher, Hans-Juergen Braun
  • Publication number: 20080022889
    Abstract: An inkjet ink composition consists essentially of a vehicle and an effective amount pigment red 168.
    Type: Application
    Filed: July 31, 2006
    Publication date: January 31, 2008
    Inventors: Howard A. Doumaux, Kathryn Nifong Burns, David M. Mahli
  • Patent number: 7270700
    Abstract: A composition comprising: (a) a compound of Formula (1) wherein: R1, R2, R3 and R4 independently are substituents; m and p independently are 0 to 3; and n and q independently are 0 to 2: provided that the compound of Formula (1) comprises at least one water solubilising group; and (b) a liquid media. Also novel compounds and ink-jet printer inks, processes and cartridges.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: September 18, 2007
    Assignee: Fujifilm Imaging Colorants Limited
    Inventor: Clive Edwin Foster
  • Patent number: 7157477
    Abstract: The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these compositions are disclosed. The present invention relates to the field of photosensitizers possessing photodynamic activities. They possess high photodynamic activities and low dark toxicities, which makes them as more potent photodynamic agents than HPD against cancer and AIDS virus.
    Type: Grant
    Filed: October 24, 2001
    Date of Patent: January 2, 2007
    Assignees: Altachem Pharma Ltd., Institute of Photographic Chemistry Academia Sinica
    Inventors: Manhua Zhang, Shangjie Xu, Tao Wu, Shen Chen, Tao Shen
  • Patent number: 6891063
    Abstract: Salts of asiatic and madecassic acid with pharmaceutically acceptable organic bases, suitable for the preparation of pharmaceutical and cosmetic compositions for the topical and systemic treatment of erithema, varicose ulcers, venous insufficiency, bedsores, delayed cicatrization, ambustions, traumatic and surgery wounds, alloeosises of the cutaneous trophism, ophthalmic alloeosises and inflammatory processes.
    Type: Grant
    Filed: April 19, 2000
    Date of Patent: May 10, 2005
    Assignee: Euphar Group S.r.l.
    Inventors: Paolo Corvi Mora, Angelo Ranise
  • Publication number: 20040092557
    Abstract: The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these compositions are disclosed. The present invention relates to the field of photosensitizers possessing photodynamic activities. They possess high photodynamic activities and low dark toxicities, which makes them as more potent photodynamic agents than HPD against cancer and AIDS virus.
    Type: Application
    Filed: August 26, 2003
    Publication date: May 13, 2004
    Inventors: Manhua Zhang, Shangjie Xu, Tao Wu, Shen Chen, Tao Shen
  • Patent number: 6562121
    Abstract: Organic pigments are conditioned by introducing a liquid prepigment suspension into a miniaturized continuous reactor and thermally treating therein.
    Type: Grant
    Filed: June 27, 2001
    Date of Patent: May 13, 2003
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Uwe Nickel, Klaus Kund, Erwin Dietz, Joachim Weber, Olaf Schupp
  • Patent number: 6344153
    Abstract: The present invention provides liquid crystal having a spiral coil structure and a dipole moment along its axis and a helical discotic switch using the same, wherein the helicene compound has the structure: wherein X is O, or S and Y is —O—C(═O)CH2—O—R5, wherein R5 is H, substituted or unsubstituted alkyl, alkenyl, cycloalkyl, aryl, or arylalkyl, wherein R1, R2, R3 and R4 are independently the same or different and are substituted or unsubstituted alkyl, alkenyl, cycloalkyl, aryl, or arylalkyl.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: February 5, 2002
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Thomas J. Katz, Colin P. Nuckolls
  • Patent number: 5326867
    Abstract: The present invention relates to intermediates, pradimic acids and pradimic acid amides of the formula (II) ##STR1## wherein R is OH or NH.sub.2 ; R.sup.1 is hydrogen or a group of the formula ##STR2## with the proviso that when R is OH, R.sup.1 is not hydrogen; Y is OH or NR.sup.2 R.sup.3 ; R.sup.2 is hydrogen or methyl; R.sup.3 is hydrogen, C.sub.1-5 alkyl, or an amino protecting group; R.sup.4 is hydrogen, hydroxy protecting group, or .beta.-D-xylosyl. The invention relates also to novel processes for the preparation of pradimic acids and pradimic acid amides, as well as novel pradimicin derivatives prepared therefrom.
    Type: Grant
    Filed: July 16, 1992
    Date of Patent: July 5, 1994
    Assignee: Bristol-Myers Squibb Company
    Inventors: Satsuki Okuyama, Takaaki Okita, Hajime Kamachi
  • Patent number: 5035747
    Abstract: Mixed crystal pigments of the anthanthrone series and preparation and use thereof Mixed crystal pigments of the anthanthrone series formed from two or more compounds of the formula I ##STR1## where R.sub.1 and R.sub.2 are each hydrogen, chlorine, bromine, iodine, nitro, cyano, amino, hydroxyl, C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, aryloxy, C.sub.1 -C.sub.4 -alkylsulfonyl, benzylsulfonyl, acetoxy, anilino, naphthindonylamino or phthalimido, wherein each component may be present in an amount of 1-99%, the preparation thereof by revatting, bead milling, dry milling, dissolving in inorganic acid and precipitating by pouring into water, and use thereof for pigmenting high molecular weight natural or synthetic organic materials.
    Type: Grant
    Filed: December 22, 1989
    Date of Patent: July 30, 1991
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Erwin Dietz, Manfred Urban