Nitrogen Double Bonded Directly At The 1- Or 4- Positions Patents (Class 552/302)
  • Publication number: 20150027483
    Abstract: The present invention relates to azomethine-type direct dyes with a tri-aromatic unit having the following formula (I): and their use for colouring keratin fibres, particularly human keratin fibres such as the hair. The invention also relates to a composition for dyeing keratin fibres comprising, in a suitable medium for dyeing, such direct dyes. Another subject of the present invention is a method for dyeing keratin fibres using said dyeing composition. Finally the present invention also relates to precursors for these direct dyes.
    Type: Application
    Filed: December 13, 2012
    Publication date: January 29, 2015
    Applicant: L'OREAL
    Inventors: Stephane Sabelle, Madeline Leduc
  • Publication number: 20140243509
    Abstract: Tissue slices and whole organisms offer substantial challenges to fluorescence imaging. Autofluorescence and absorption via intrinsic chromophores, such as flavins, melanin, and hemoglobins, confound and degrade output from all fluorescent tags. An “optical window,” farther red than most autofluorescence sources and in a region of low hemoglobin and water absorbance, lies between 650 and 900 nm. This valley of relative optical clarity is an attractive target for fluorescence-based studies within tissues, intact organs, and living organisms. Novel fluorescent tags were developed herein, based upon a genetically targeted fluorogen activating protein and cognate fluorogenic dye that yields emission with a peak at 733 nm exclusively when complexed as a “fluoromodule”. This tool improves substantially over previously described far-red/NIR fluorescent proteins in terms of brightness, wavelength, and flexibility by leveraging the flexibility of synthetic chemistry to produce novel chromophores.
    Type: Application
    Filed: June 18, 2013
    Publication date: August 28, 2014
    Inventors: Subhasish K. Chakraborty, Mingrui Zhang, Alan S. Waggoner
  • Patent number: 8801808
    Abstract: One subject of the present invention is a dye composition comprising benzyl alcohol, at least one C1-C4 monoalcohol and at least one anthraquinone direct dye of formula (I) or azomethine direct dye of formula (II). The composition of the invention makes it possible to obtain colorings that are intense and resistant.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: August 12, 2014
    Assignee: L'oreal
    Inventors: Boris Lalleman, Alain Lagrange
  • Publication number: 20140148606
    Abstract: Disclosed is a methyl violet derivative having inhibitory activity against allosteric focal adhesion kinase (FAK) and is useful as an agent for preventing or treating cancer.
    Type: Application
    Filed: October 29, 2013
    Publication date: May 29, 2014
    Applicant: Korea Institute of Science and Technology
    Inventors: Tae Bo SIM, Hwan KIM
  • Patent number: 8083809
    Abstract: The invention relates to the dyeing of keratinous fibres using azomethine direct dyes of formula (I) or reduced precursors of azomethine direct dyes of formula (II) obtained from 2-chloro-3-amino-6-methylphenol. A subject-matter of the invention is a dyeing composition comprising at least one chlorinated azomethine direct dye or one reduced precursor of a chlorinated azomethine direct dye, a method for dyeing keratinous fibres which employs the said composition and their uses in the dyeing of keratinous fibres. This composition makes it possible to obtain a particularly stable and consistent colouring.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: December 27, 2011
    Assignee: L'Oreal S.A.
    Inventors: Madeleine Leduc, Stéphane Sabelle, Eric Metais, Christophe Rondot
  • Patent number: 7645304
    Abstract: The subject of the present invention is the use, for dyeing in particular human keratin materials, of a specific direct azomethine dye, by dry thermal transfer. Its subject is furthermore a method for dyeing keratin materials, in which at least one direct azomethine dye contained in a dry composition, is applied to or close to the keratin materials, and a source of heat is applied, causing the thermal transfer of the direct dye(s) at the surface and/or inside the keratin materials. It relates furthermore to the dry composition and a method for preparing it.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: January 12, 2010
    Assignee: L'Oreal S.A.
    Inventors: Grégory Plos, Luc Gourlaouen, Jean-Dominique Bazin De Bezons
  • Patent number: 7521006
    Abstract: Disclosed is a near-infrared absorbing compound which does not contain antimony or arsenic, and has excellent stability, especially excellent heat resistance, light resistance and moist heat resistance. Also disclosed are a near-infrared absorbing filter, which is produced by using the near-infrared absorbing compound, and has excellent resistance such as light resistance and heat resistance, an optical filter and an optical recording medium. Specifically disclosed are a diimmonium compound represented by the formula (1) below and a near-infrared absorbing filter obtained by using such a diimmonium compound. Further specifically disclosed are a near-infrared absorbing filter wherein an adhesive layer containing the diimmonium compound is arranged on a transparent supporting body, and an optical filter using such a near-infrared absorbing filter.
    Type: Grant
    Filed: September 2, 2005
    Date of Patent: April 21, 2009
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Masaaki Ikeda, Takaaki Kurata, Syouichi Kaneko, Junichi Segawa
  • Patent number: 7056349
    Abstract: The invention relates to an agent for colouring fibres (A). Said agent is produced by mixing two constituents (A1) and (A2), and is characterised in that the constituent (A1) contains at least one quinonimine derivative of formula (I), and the constituent (A2) contains at least one compound from the group consisting of aromatic amines and phenols. The invention also relates to a method for colouring keratin fibres using the inventive agent.
    Type: Grant
    Filed: February 23, 2002
    Date of Patent: June 6, 2006
    Assignee: Wella AG
    Inventors: Cécile Pasquier, Veronique Buclin-Charrière, Patrick Wyss
  • Publication number: 20040241749
    Abstract: The invention provides Zn-chelating compounds that are molecularly engineered to bind to a specific target sequence in a protein of interest. The Zn2+ ion is far less toxic and promiscuous than nickel and therefore provides an attractive alternative to Ni-based labeling systems. Invention Zn-chelating compounds also do not require oxidizable thiols and therefore can be used in non-reducing environments such as the surface of living cells. In addition, the target sequence is genetically encodable and requires incorporation of only a few amino acids, unlike fusions to fluorescent proteins such as GFP.
    Type: Application
    Filed: January 16, 2004
    Publication date: December 2, 2004
    Inventors: Roger Y. Tsien, Christina Hauser
  • Publication number: 20030050489
    Abstract: A method for purifying an electronic item material, which comprises dissolving an electronic item material or its intermediate product in an organic solvent and having the solution contacted with activated clay at a temperature of 65° C. to 200° C.
    Type: Application
    Filed: June 29, 2001
    Publication date: March 13, 2003
    Applicant: Hodogaya Chemical Co., Ltd.
    Inventors: Katsumi Abe, Tomonori Nishimura, Takanobu Watanabe, Susumu Suzuka
  • Publication number: 20020111501
    Abstract: A process for synthesizing 2-amino-5-dimethlyaminophenyl thiosulfonic acid comprises the step of oxidizing N,N′-dimethyl-&rgr;-phenylene-diamine in the presence of a source of thiosulfate ions, while maintaining the temperature of the reaction mixture not higher than about 10° C. This compound is useful as an intermediate in the synthesis of toluidine blue ∘.
    Type: Application
    Filed: March 11, 2002
    Publication date: August 15, 2002
    Inventor: Douglas D. Burkett
  • Publication number: 20020052519
    Abstract: The present invention provides a new charge transport agent for use in a photosensitive layer in a positive-electrification-type electrophotographic photoconductor that can be used with high speed copying machines. The electrophotographic photoconductor of the invention includes an electrically conductive substrate and a photosensitive layer on the substrate. The photosensitive layer contains a charge generation agent and an electron transport compound described by the following general formula (I).
    Type: Application
    Filed: June 18, 2001
    Publication date: May 2, 2002
    Inventor: Masami Kuroda
  • Patent number: 6187937
    Abstract: A hydroxydiphenylamine compound can be converted to an N-phenylquinoneimine by reacting the hydroxydiphenylamine with oxygen or an oxygen containing gas in the presence of a modified activated carbon catalyst, the catalyst having had surface oxides removed therefrom.
    Type: Grant
    Filed: December 23, 1998
    Date of Patent: February 13, 2001
    Assignee: Flexsys America L.P.
    Inventors: Donald L. Fields, Jr., Michael K. Stern, Jayant Shivji Lodaya
  • Patent number: 6114554
    Abstract: A phenylenediamine compound can be converted, with high selectivity, into its corresponding quinonediimine by reacting the phenylenediamine with a hypochlorite oxidation reactant.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: September 5, 2000
    Assignee: Flexsys America L.P.
    Inventors: Jayant Shivji Lodaya, Raymond Anton Lohr, Jr., Donald Lee Fields, Jr.
  • Patent number: 6072061
    Abstract: A hydroxyphenylamine compound can be converted, with high yield and high selectivity, into its corresponding quinoneimine by reacting the hydroxyphenylamine with a hypochlorite oxidation reactant.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: June 6, 2000
    Assignee: Flexsys America L.P.
    Inventors: Donald L. Fields, Jr., Jayant S. Lodaya
  • Patent number: 6043384
    Abstract: A hydroxyphenylamine compound can be converted, with high selectivity, into its corresponding quinoneimine by reacting the hydroxyphenylamine with hydrogen peroxide in the presence of a catalyst.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: March 28, 2000
    Assignee: Flexsys America L.P.
    Inventors: Donald L. Fields, Jr., Raymond Lohr, Jr., Jayant S. Lodaya
  • Patent number: 5959126
    Abstract: A phenylenediamine compound can be converted, with high selectivity, into its corresponding quinonediimine by reacting the phenylenediamine with oxygen in the presence of a modified activated carbon catalyst in an aqueous system.
    Type: Grant
    Filed: February 12, 1998
    Date of Patent: September 28, 1999
    Assignee: Flexsys America L. P.
    Inventors: Raymond Anton Lohr, Jr., Otto William Maender, Donald Lee Fields, Jr.
  • Patent number: 5919846
    Abstract: A novel colorant compound is provided which is the addition product of an organic chromophore having at least one reactive hydroxyl or amine substituent, a polyisocyanate, and a carboxylic acid, sulfonic acid, or salt of either thereof. The polyisocyanate, added in a molar excess relative to the number of such reactive substituents, reacts with the reactive hydroxyl or amine groups to provide terminal isocyanate groups. Subsequently, the carboxylic acid or salt thereof, also added in an amount excessive in relation to the number of terminal isocyanate groups, reacts therewith to from urethane moieties on the colorant. Such a compound provides excellent ink compositions upon dilution and are very soluble within all the standard ink diluents. Furthermore, such colorants provide good jettability, waterfastness, washfastness, and the like, within ink-jet applications on various types of printing substrates.
    Type: Grant
    Filed: February 19, 1998
    Date of Patent: July 6, 1999
    Assignee: Milliken Research Corporation
    Inventors: Raj Batlaw, John W. Miley
  • Patent number: 5811370
    Abstract: Azamethine dyes of the formula ##STR1## where W is oxygen, sulfur or a radical of the formula --NH--CO--, --NH--COO-- oder --NH--SO.sub.2 --,Z.sup.1 is C.sub.1 -C.sub.4 -alkyl with or without substitution, phenyl or C.sub.1 -C.sub.4 -alkoxy,Z.sup.2 and Z.sup.3 are each hydrogen or C.sub.1 -C.sub.4 -alkyl with or without substitution, provided --CZ.sup.1 Z.sup.2 Z.sup.3 is not linear and is not isopropyl,Z.sup.4 is hydrogen, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy,Z.sup.5 and Z.sup.6 are each C.sub.1 -C.sub.10 -alkyl with or without substitution, C.sub.3 -C.sub.4 -alkenyl, C.sub.5 -C.sub.7 -cycloalkyl, phenyl or tolyl, or together with the nitrogen atom joining them together a heterocyclic radical or Z.sup.4 and Z.sup.5 are together a bridge member, andT is a radical of a cyclic acidic--CH compound H.sub.2 T,are useful for thermal transfer.
    Type: Grant
    Filed: May 8, 1997
    Date of Patent: September 22, 1998
    Assignee: BASF Aktiengesellschaft
    Inventors: Rudiger Sens, Andreas Johann Schmidt, Stefan Beckmann, Karl-Heinz Etzbach
  • Patent number: 5514819
    Abstract: The present invention provides a dye-donor element for use according to thermal dye sublimation transfer, said dye-donor element comprising a support provided with a dye layer containing a dye and a polymeric binder, characterized in that said dye corresponds to the following formula: ##STR1## wherein R.sup.1 to R.sup.12 are as set out in the claims and the description.
    Type: Grant
    Filed: September 20, 1994
    Date of Patent: May 7, 1996
    Assignee: Agfa-Gevaert N.V.
    Inventor: Luc Vanmaele
  • Patent number: 5292905
    Abstract: A cyan dye of the formula: ##STR1## wherein X.sup.1 represents halogen; X.sup.2 represents hydrogen, alkyl, alkoxy, halogen, alkylcarbonylamino or perfluoroalkyl; R.sup.1 and R.sup.2 independently represent alkyl, phenyl, perfluoroalkyl, halogen-substituted alkyl, or halogen-substituted phenyl or alkyl-substituted phenyl; R.sub.3 represents alkyl; R.sup.4 represents alkyl, alkoxy or perfluoroalkyl; and n is an integer of 1 or more. A thermal transfer sheet comprising a substrate and an ink layer, the ink layer comprising a cyan dye of the formula described above, is also disclosed.
    Type: Grant
    Filed: March 13, 1992
    Date of Patent: March 8, 1994
    Assignee: Sony Corporation
    Inventors: Toshihisa Inoue, Tetsuya Abe, Yoshio Fujiwara
  • Patent number: 5273906
    Abstract: The present invention provides novel dyes for staining proteins, particularly those in electrophoretic gels. The dyes of the invention are derivatives of Coomassie.RTM. dyes. The invention also provides quantitative and qualitative methods for detecting proteins by staining the proteins with a dye of the invention.
    Type: Grant
    Filed: July 20, 1992
    Date of Patent: December 28, 1993
    Assignee: Promega Corporation
    Inventors: John W. Shultz, David L. Leland
  • Patent number: 5178637
    Abstract: The invention relates to the use of a 5,6-dihydroxyindoline corresponding to the formula (I): ##STR1## in which R represents a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group, as well as the acid addition salts of these compounds for dyeing keratinous materials, in particular human keratinous materials,and to the tinctorial compositions and methods employed.
    Type: Grant
    Filed: May 31, 1991
    Date of Patent: January 12, 1993
    Assignee: L'Oreal
    Inventors: Alain Lagrange, Bernadette Luppi, Alex Junino
  • Patent number: 5132438
    Abstract: Bichromophoric methine and azamethine transfer dyes have the formulaZ.sup.2 --Z.sup.1 --LY.sup.1 --Y.sup.2whereL is a bridge member which does not permit any conjugation of .pi.-electrons between Z.sup.1 and Y.sup.1,Y.sup.1 and Z.sup.1 are each independently of the other aminophenylene, which may be benzofused, or heterocyclyl andY.sup.2 and Z.sup.2 are each independently of the other benzoquinoeiminyl, which may be benzofused, or heterocyclyl.
    Type: Grant
    Filed: February 4, 1991
    Date of Patent: July 21, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Volker Bach, Karl-Heinz Etzbach, Ruediger Sens
  • Patent number: 5132439
    Abstract: The present invention provides novel dyes for staining protein, particularly those in elecrophoretic gels. The dyes of the invention are derivatives of Coomassie.RTM. dyes. The invention also provides quantitative and qualitative methods for detecting proteins which comprise staining the proteins with a dye of the invention.
    Type: Grant
    Filed: November 19, 1990
    Date of Patent: July 21, 1992
    Assignee: Promega Corporation
    Inventors: John W. Schultz, David L. Leland
  • Patent number: 5091545
    Abstract: The present invention relates to a process for the catalytic oxidation of hydroxy containing aromatic compounds to form the respective quinone compounds comprising contacting a hydroxy containing aromatic compound of the formula: ##STR1## with a molecular oxygen containing gas in the presence of: (a) a catalytic amount of a cobalt (II) compound,(b) a primary aliphatic amine having the nitrogen atom attached to a tertiary carbon, and(c) an alcohol selected from the group consisting of methyl alcohol, ethyl alcohol, isopropyl alcohol, butyl alcohol, 2,2,2-trifluoroethanol and benzyl alcohol,wherein X is of the formula ##STR2## wherein R is individually selected from the group of radicals consisting of hydrogen, an alkyl having from about 1 to about 18 carbon atoms, an alkoxy having from about 1 to 8 carbon atoms, a phenyl and an aralkyl having 7 to 12 carbon atoms.
    Type: Grant
    Filed: March 2, 1990
    Date of Patent: February 25, 1992
    Assignee: The Goodyear Tire & Rubber Company
    Inventor: Dane K. Parker
  • Patent number: 5013857
    Abstract: Process for the preparation of sulpho-free triphenylmethane dyestuffs of the formula ##STR1## in which R.sup.1 -R.sup.3 denote hydrogen, C.sub.1 -C.sub.6 -alkyl, preferably methyl, or halogen, preferably chlorine,Y denotes hydrogen or NX.sup.5 X.sup.6,X.sup.1 -X.sup.6 denote hydrogen, C.sub.1 -C.sub.6 -alkyl, preferably methyl, ethyl, benzyl or phenyl andZ.sup.
    Type: Grant
    Filed: December 11, 1989
    Date of Patent: May 7, 1991
    Assignee: Bayer Aktiengesellschaft
    Inventors: Horst Berneth, Roderich Raue